The harmony of a relationship between teachers and students is a powerful promotion to the students＇ mental health. A ＂shared＂ relationship between teachers and students is advocated now. In the construction of a h...The harmony of a relationship between teachers and students is a powerful promotion to the students＇ mental health. A ＂shared＂ relationship between teachers and students is advocated now. In the construction of a harmonious relationship between teachers and students, the positions of the teachers and students in teaching should be first made clear, and then an effective mental communication between teachers and students is necessarily available.展开更多
Family education is the earliest education that a person receives after birth, and also the enlightenment education. It plays an irreplaceable role in the three aspects of individual acquiring knowledge, cultivating a...Family education is the earliest education that a person receives after birth, and also the enlightenment education. It plays an irreplaceable role in the three aspects of individual acquiring knowledge, cultivating ability and forming personality. In reality, there are different problems in different family structures, that is, the "left-behind family", "single-parent family" and "core family" all have various and different degrees of family problems, which have different effects on the physical and mental development of teenagers. Now I talk about the impact of family education on the physical and mental development of teenagers. I hope that family education plays an negligible role in the mental health of teenagers, which is related to the healthy growth of teenagers.展开更多
Background Recombinant human growth hormone(rhGH)therapy has shown to improve height and body composition in children with Prader–Willi syndrome(PWS),the evidence of early rhGH treatment on motor and mental developme...Background Recombinant human growth hormone(rhGH)therapy has shown to improve height and body composition in children with Prader–Willi syndrome(PWS),the evidence of early rhGH treatment on motor and mental development is still accumulating.This study explored the time effect on psychomotor development,anthropometric indexes,and safety for infants and young children with PWS.Methods A phase 3,single-arm,multicenter,self-controlled study was conducted in six sites.Patients received rhGH at 0.5 mg/m2/day for first four weeks,and 1 mg/m2/day thereafter for up to 52 weeks.Motor development was measured using Peabody Developmental Motor Scales-second edition,mental development using Griffiths Development Scales-Chinese(GDS-C).Height standard deviation score(SDS),body weight SDS,and body mass index(BMI)SDS were also assessed.Results Thirty-five patients were enrolled totally.Significant improvements were observed in height,body weight,and BMI SDS at week 52;GDS-C score showed significant improvement in general quotient(GQ)and sub-quotients.In a linear regression analysis,total motor quotient(TMQ),gross motor quotient(GMQ),and fine motor quotient were negatively correlated with age;however,treatment may attenuate deterioration of TMQ and GMQ.Changes in GQ and locomotor sub-quotient in<9-month group were significantly higher than≥9-month group.Mild to moderate severity adverse drug reactions were reported in six patients.Conclusion Fifty-two-week treatment with rhGH improved growth,BMI,mental development,and lessened the deterioration of motor function in infants and young children with PWS.Improved mental development was more pronounced when instituted in patients<9 months old.展开更多
The proposed universal psychological mechanism for developmental psychology is the mental protective system whose different parts emerge and mature in the eight different stages of psychosocial protective development ...The proposed universal psychological mechanism for developmental psychology is the mental protective system whose different parts emerge and mature in the eight different stages of psychosocial protective development under different social interactions. The proposed eight stages of psychosocial protective development are childhood (infancy, toddlerhood, pre-juvenile age, and juvenile age), adolescence, early young adulthood, late young adulthood, early middle adulthood, late middle adulthood, early late adulthood, and late late adulthood. The mental protection system consists of four socialities (collectivistic, individualistic, interdependent, and generativity), three worldviews (territorial, competitive, and cooperative), and the mental immune system for four regulated and unregulated countermeasures (hyperactivity, phobia, comforter, and rationality) against adversities. During childhood, dependent children have collectivistic sociality under the protection of committed parents and territorial worldview with the boundary of family. Children start with the unregulated mental immune system without delayed gratification due to mental immaturity, and gradually acquire the regulated mental immune system with delayed gratification through mental maturity. Adolescents transit to adulthood. Independent adults have the regulated metal immune system, individualistic sociality with reciprocity, and competitive-cooperative worldviews without boundary. After the age of 50, older people as elder leaders-mentors develop generativity sociality to protect next generation. The paper shows that the mental protective system as the universal psychological mechanism for developmental psychology explains clearly psychosocial protective development, the human evolution, the Piaget’s cognitive development, the Erikson’s psychosocial (ego-social) development, the Confucius’ (educated person’s) six milestones of life, and parent-child relation in the Abrahamic religions (Judaism, Christianity, and Islam) and Confucianism.展开更多
Purpose: The purpose of this study was to clarify the relationship and experiences of occupational health nurses (OHNs) and related departments in project development of mental health care for primary treatment in the...Purpose: The purpose of this study was to clarify the relationship and experiences of occupational health nurses (OHNs) and related departments in project development of mental health care for primary treatment in the Japanese occupational health setting. Method: A total of 235 OHNs who are members of the Japan Academy of Occupational Health Nursing were sent an anonymous self-administered questionnaire survey. The questionnaire included items on the following: the OHN’s background, whether the OHN had experience in project development, the communication between the associated departments, the Japanese version of the Work Engagement Scale (UWES-J), occupational assessments, workplace assessments, and the Transtheoretical Model (TTM) for health promotion in companies and the OHN’s working environment. We performed logistic regression analysis to examine the relationship between experience and these harmonious relationships with other associated departments. Result: Responses from 61 OHNs (valid response rate: 25.9%) were analyzed. The mean number of years of service as an OHN was 18.9, and 82% of respondents had experience in project development. The logistic analysis further revealed that OHNs who had experience in project development of mental health care usually had a harmonious relationship with other associated departments. Conclusion: To promote mental health care for workers, OHNs have the capability to create individual and workplace assessments, enhance their work engagement, and make further improvements to their working environment. .展开更多
This article aims to investigate the public's sustainability mental model(SMM), which can reveal the sustainability dilemma from the public respective, other than enterprise or government. In this article, SMM is ...This article aims to investigate the public's sustainability mental model(SMM), which can reveal the sustainability dilemma from the public respective, other than enterprise or government. In this article, SMM is defined as one's cognitive structure, thinking mode, and behavior tendency when someone deals with sustainability issues. After theoretical analysis, the authors developed reliable and valid measures systematically and conducted a typical survey with 581 participants from college students' families in Guangdong province in China. Based on those samples, the author used the exploratory factor analysis and confirmatory factor analysis to construct a measurement model of SMM, which includes three dimensions, i.e. sustainable cognition, sustainable thinking, and sustainable behavior intention. According to SMM survey and clustering analysis, the results indicate that SMM of those participants is inactive. Even though those samples do not represent the whole country comprehensively, but this survey was sampled typically and they came from around China. So, the authors consider the SMM scores can reflect Chinese people to some extent, leading to the assumption that SMM of Chinese people is not active presently.展开更多
目的探讨Ⅰ型神经纤维瘤病(NF1)基因变异合并细胞周期蛋白依赖性激酶13(CDK13)基因变异患儿的临床特征和遗传学特点。方法收集1例NF1合并CDK13相关疾病患儿的临床资料,对患儿及其父母进行全外显子组测序,采用Sanger测序验证可疑变异,并...目的探讨Ⅰ型神经纤维瘤病(NF1)基因变异合并细胞周期蛋白依赖性激酶13(CDK13)基因变异患儿的临床特征和遗传学特点。方法收集1例NF1合并CDK13相关疾病患儿的临床资料,对患儿及其父母进行全外显子组测序,采用Sanger测序验证可疑变异,并进行家系分析。以“CDK13基因和NF1基因”或“CDK13 gene and NF1 gene”为检索词分别检索中国知网、万方数据知识服务平台和PubMed数据库建库至2024年2月的相关文献,总结同患NF1和CDK13相关疾病患者的临床表型和遗传学特征。结果患儿,男,13岁,主要临床表现为皮肤牛奶咖啡斑,矮小身材,特殊面容(上眼睑外斜、宽眼距、内眦赘皮、鼻梁宽),智力障碍。患儿存在NF1基因杂合变异c.3610C>G(p.Arg1204Gly)和CDK13基因移码突变c.484dupG(p.Ala162Glyfs*108)(杂合)。Sanger测序验证结果显示,患儿母亲携带NF1基因杂合变异,未携带CDK13基因移码突变;父亲均未携带。未检索到关于同患NF1和CDK13相关疾病的患者的文献。共检索到CDK13相关疾病文献11篇,文献复习结果显示,97例患者主要临床表现为智力障碍或发育迟缓、特殊面容、先天性心脏缺陷,致病变异以错义突变为主。结论NF1基因变异可导致NF1。当发现有特殊面容的NF1患儿出现无法解释的现有表型或症状时,应注意2种遗传病同时存在的可能性。展开更多
目的应用高分辨微阵列比较基因组杂交技术（array—comparative genomic hybridization，aCGH）对55例不明原阂的智力低下或发育迟缓（mental retardation or developmental delay，MR／DD）患儿进行拷贝数变异（copy number variations...目的应用高分辨微阵列比较基因组杂交技术（array—comparative genomic hybridization，aCGH）对55例不明原阂的智力低下或发育迟缓（mental retardation or developmental delay，MR／DD）患儿进行拷贝数变异（copy number variations，CNVs）检测，寻求与遗传学相关的致病因素，探讨aCGH对不明原因MR／DD患儿可能的分子病因诊断的作用。方法收集2013年6月-2013年12月到本院儿科初步诊断为MR／DD的患儿55例，应用25～50K CytoScanHD芯片检测全基因组CNVs，联合生物信息学分析手段分析致病性CNVs。结果在55例不明原因MR／DD患者中共检测到21例存在罕见CNVs。通过比对数据库，21处CNVs确认为致病性CNVs。19例患者携带与MR／DD相关的CNVs。2例为已知综合征患者，其中1例为Turner综合征，1例为1p36缺失综合征。结论基因组CNVs相关的微缺失或微重复是不明原因MR／DD的病因之一，这些片段均无法被常规染色体G带检查所识别。aCGH可以提高对不明原因MR／DD患儿的分子病因诊断水平，对深入研究MR／DD病因机制有重要意义，为患儿预后和家庭再发风险评估提供指导。展开更多
文摘The harmony of a relationship between teachers and students is a powerful promotion to the students＇ mental health. A ＂shared＂ relationship between teachers and students is advocated now. In the construction of a harmonious relationship between teachers and students, the positions of the teachers and students in teaching should be first made clear, and then an effective mental communication between teachers and students is necessarily available.
文摘Family education is the earliest education that a person receives after birth, and also the enlightenment education. It plays an irreplaceable role in the three aspects of individual acquiring knowledge, cultivating ability and forming personality. In reality, there are different problems in different family structures, that is, the "left-behind family", "single-parent family" and "core family" all have various and different degrees of family problems, which have different effects on the physical and mental development of teenagers. Now I talk about the impact of family education on the physical and mental development of teenagers. I hope that family education plays an negligible role in the mental health of teenagers, which is related to the healthy growth of teenagers.
文摘Background Recombinant human growth hormone(rhGH)therapy has shown to improve height and body composition in children with Prader–Willi syndrome(PWS),the evidence of early rhGH treatment on motor and mental development is still accumulating.This study explored the time effect on psychomotor development,anthropometric indexes,and safety for infants and young children with PWS.Methods A phase 3,single-arm,multicenter,self-controlled study was conducted in six sites.Patients received rhGH at 0.5 mg/m2/day for first four weeks,and 1 mg/m2/day thereafter for up to 52 weeks.Motor development was measured using Peabody Developmental Motor Scales-second edition,mental development using Griffiths Development Scales-Chinese(GDS-C).Height standard deviation score(SDS),body weight SDS,and body mass index(BMI)SDS were also assessed.Results Thirty-five patients were enrolled totally.Significant improvements were observed in height,body weight,and BMI SDS at week 52;GDS-C score showed significant improvement in general quotient(GQ)and sub-quotients.In a linear regression analysis,total motor quotient(TMQ),gross motor quotient(GMQ),and fine motor quotient were negatively correlated with age;however,treatment may attenuate deterioration of TMQ and GMQ.Changes in GQ and locomotor sub-quotient in<9-month group were significantly higher than≥9-month group.Mild to moderate severity adverse drug reactions were reported in six patients.Conclusion Fifty-two-week treatment with rhGH improved growth,BMI,mental development,and lessened the deterioration of motor function in infants and young children with PWS.Improved mental development was more pronounced when instituted in patients<9 months old.
文摘The proposed universal psychological mechanism for developmental psychology is the mental protective system whose different parts emerge and mature in the eight different stages of psychosocial protective development under different social interactions. The proposed eight stages of psychosocial protective development are childhood (infancy, toddlerhood, pre-juvenile age, and juvenile age), adolescence, early young adulthood, late young adulthood, early middle adulthood, late middle adulthood, early late adulthood, and late late adulthood. The mental protection system consists of four socialities (collectivistic, individualistic, interdependent, and generativity), three worldviews (territorial, competitive, and cooperative), and the mental immune system for four regulated and unregulated countermeasures (hyperactivity, phobia, comforter, and rationality) against adversities. During childhood, dependent children have collectivistic sociality under the protection of committed parents and territorial worldview with the boundary of family. Children start with the unregulated mental immune system without delayed gratification due to mental immaturity, and gradually acquire the regulated mental immune system with delayed gratification through mental maturity. Adolescents transit to adulthood. Independent adults have the regulated metal immune system, individualistic sociality with reciprocity, and competitive-cooperative worldviews without boundary. After the age of 50, older people as elder leaders-mentors develop generativity sociality to protect next generation. The paper shows that the mental protective system as the universal psychological mechanism for developmental psychology explains clearly psychosocial protective development, the human evolution, the Piaget’s cognitive development, the Erikson’s psychosocial (ego-social) development, the Confucius’ (educated person’s) six milestones of life, and parent-child relation in the Abrahamic religions (Judaism, Christianity, and Islam) and Confucianism.
文摘Purpose: The purpose of this study was to clarify the relationship and experiences of occupational health nurses (OHNs) and related departments in project development of mental health care for primary treatment in the Japanese occupational health setting. Method: A total of 235 OHNs who are members of the Japan Academy of Occupational Health Nursing were sent an anonymous self-administered questionnaire survey. The questionnaire included items on the following: the OHN’s background, whether the OHN had experience in project development, the communication between the associated departments, the Japanese version of the Work Engagement Scale (UWES-J), occupational assessments, workplace assessments, and the Transtheoretical Model (TTM) for health promotion in companies and the OHN’s working environment. We performed logistic regression analysis to examine the relationship between experience and these harmonious relationships with other associated departments. Result: Responses from 61 OHNs (valid response rate: 25.9%) were analyzed. The mean number of years of service as an OHN was 18.9, and 82% of respondents had experience in project development. The logistic analysis further revealed that OHNs who had experience in project development of mental health care usually had a harmonious relationship with other associated departments. Conclusion: To promote mental health care for workers, OHNs have the capability to create individual and workplace assessments, enhance their work engagement, and make further improvements to their working environment. .
基金supported by Guangdong Higher Educational Promoting Program of"The Study on Emerging Mechanism of Brand Sustainability":[Grant Number 2014WTSCX120]Guangdong Natural Science Fund Program of"Research on the Complicated System of Brand Sustainability":[Grant Number 2015A030313703]
文摘This article aims to investigate the public's sustainability mental model(SMM), which can reveal the sustainability dilemma from the public respective, other than enterprise or government. In this article, SMM is defined as one's cognitive structure, thinking mode, and behavior tendency when someone deals with sustainability issues. After theoretical analysis, the authors developed reliable and valid measures systematically and conducted a typical survey with 581 participants from college students' families in Guangdong province in China. Based on those samples, the author used the exploratory factor analysis and confirmatory factor analysis to construct a measurement model of SMM, which includes three dimensions, i.e. sustainable cognition, sustainable thinking, and sustainable behavior intention. According to SMM survey and clustering analysis, the results indicate that SMM of those participants is inactive. Even though those samples do not represent the whole country comprehensively, but this survey was sampled typically and they came from around China. So, the authors consider the SMM scores can reflect Chinese people to some extent, leading to the assumption that SMM of Chinese people is not active presently.
文摘目的探讨Ⅰ型神经纤维瘤病(NF1)基因变异合并细胞周期蛋白依赖性激酶13(CDK13)基因变异患儿的临床特征和遗传学特点。方法收集1例NF1合并CDK13相关疾病患儿的临床资料,对患儿及其父母进行全外显子组测序,采用Sanger测序验证可疑变异,并进行家系分析。以“CDK13基因和NF1基因”或“CDK13 gene and NF1 gene”为检索词分别检索中国知网、万方数据知识服务平台和PubMed数据库建库至2024年2月的相关文献,总结同患NF1和CDK13相关疾病患者的临床表型和遗传学特征。结果患儿,男,13岁,主要临床表现为皮肤牛奶咖啡斑,矮小身材,特殊面容(上眼睑外斜、宽眼距、内眦赘皮、鼻梁宽),智力障碍。患儿存在NF1基因杂合变异c.3610C>G(p.Arg1204Gly)和CDK13基因移码突变c.484dupG(p.Ala162Glyfs*108)(杂合)。Sanger测序验证结果显示,患儿母亲携带NF1基因杂合变异,未携带CDK13基因移码突变;父亲均未携带。未检索到关于同患NF1和CDK13相关疾病的患者的文献。共检索到CDK13相关疾病文献11篇,文献复习结果显示,97例患者主要临床表现为智力障碍或发育迟缓、特殊面容、先天性心脏缺陷,致病变异以错义突变为主。结论NF1基因变异可导致NF1。当发现有特殊面容的NF1患儿出现无法解释的现有表型或症状时,应注意2种遗传病同时存在的可能性。
文摘目的应用高分辨微阵列比较基因组杂交技术（array—comparative genomic hybridization，aCGH）对55例不明原阂的智力低下或发育迟缓（mental retardation or developmental delay，MR／DD）患儿进行拷贝数变异（copy number variations，CNVs）检测，寻求与遗传学相关的致病因素，探讨aCGH对不明原因MR／DD患儿可能的分子病因诊断的作用。方法收集2013年6月-2013年12月到本院儿科初步诊断为MR／DD的患儿55例，应用25～50K CytoScanHD芯片检测全基因组CNVs，联合生物信息学分析手段分析致病性CNVs。结果在55例不明原因MR／DD患者中共检测到21例存在罕见CNVs。通过比对数据库，21处CNVs确认为致病性CNVs。19例患者携带与MR／DD相关的CNVs。2例为已知综合征患者，其中1例为Turner综合征，1例为1p36缺失综合征。结论基因组CNVs相关的微缺失或微重复是不明原因MR／DD的病因之一，这些片段均无法被常规染色体G带检查所识别。aCGH可以提高对不明原因MR／DD患儿的分子病因诊断水平，对深入研究MR／DD病因机制有重要意义，为患儿预后和家庭再发风险评估提供指导。
