This study introduces a comprehensive theoretical framework for accurately calculating the electronic band-structure of strained long-wavelength InAs/GaSb type-Ⅱsuperlattices.Utilizing an eight-band k·p Hamilto⁃...This study introduces a comprehensive theoretical framework for accurately calculating the electronic band-structure of strained long-wavelength InAs/GaSb type-Ⅱsuperlattices.Utilizing an eight-band k·p Hamilto⁃nian in conjunction with a scattering matrix method,the model effectively incorporates quantum confinement,strain effects,and interface states.This robust and numerically stable approach achieves exceptional agreement with experimental data,offering a reliable tool for analyzing and engineering the band structure of complex multi⁃layer systems.展开更多
Hetero-deformation induced(HDI) strengthening generally yields a weak effect on the mechanical property improvement of particle-reinforced metal matrix composites(MMCs). In the present work, a novel strategy was repor...Hetero-deformation induced(HDI) strengthening generally yields a weak effect on the mechanical property improvement of particle-reinforced metal matrix composites(MMCs). In the present work, a novel strategy was reported to induce remarkable HDI strengthening in MMCs by selecting a reinforcing material with excellent geometrically necessary dislocation(GND) storage ability. The viability of the proposed strategy was tested on additively manufactured nickel matrix composites consisting of Inconel 625 alloy(IN625) as the matrix and high-entropy alloy VNbMoTa as the reinforcing material. It was found that the average grain size and dislocation density of the additively manufactured MMCs gradually decreased with the increase in the additional amount of VNbMoTa. All the samples possessed a similar two-layer VNbMoTa-matrix interface structure containing a high-entropy alloy layer and a Laves phase layer;however, the interface width varied. This two-layer interface could hold GND pile-ups without breaking to ensure a good load transfer effect, and ductile VNbMoTa particles demonstrated excellent GND storage capacity to induce significant HDI stress. The HDI stress for the IN625-(10 wt%)VNbMoTa sample was approximately 200 MPa higher than that for the pure IN625 alloy, resulting in an excellent strength-ductility synergy. The yield strength and elongation of the IN625-(10 wt%)VNbMoTa sample reached(1 032.5 ± 18.8)MPa and(11.8 ± 1.2)%, respectively. In addition, the IN625-(10 wt%)VNbMoTa composite also demonstrated superior mechanical properties at 650℃ that were comparable to those at room temperature, implying that VNbMoTa addition remarkably limited strength reduction caused by temperature. Deformable VNbMoTa particles effectively alleviated the stress concentration, delayed the crack initiation, generated more dislocations and pile-ups, and, in turn, improved the overall high-temperature strength of composites.展开更多
A polarized bidirectional reflectance distribution function(pBRDF)matrix is developed from two-scale roughness theory with the aim of providing more accurate simulations of microwave emissions and scattering required ...A polarized bidirectional reflectance distribution function(pBRDF)matrix is developed from two-scale roughness theory with the aim of providing more accurate simulations of microwave emissions and scattering required for ocean-atmosphere coupled radiative transfer models.The potential of the pBRDF matrix is explored for simu-lating the ocean backscatter at Ku-band.The effects of ocean wave spectra including the modified Durden and Vesecky(DV2),Elfouhaily,and Kudryavtsev spectra on the pBRDF matrix backscatter simulations are investi-gated.Additionally,the differences in backscattering normalized radar cross-section(NRCS)simulations between the Ku-band geophysical model function and pBRDF matrix are analyzed.The results show that the pBRDF matrix can reasonably reproduce the spatial distribution of ocean surface backscattering energy,but the distribution pat-tern and numerical values are influenced by ocean wave spectra.The DV2 spectrum is the best one for the pBRDF matrix to simulate horizontally polarized NRCSs,with the exception of scenarios where the incidence angle is below 35°,the wind speed is less than 10 m s^(−1),and in the cross-wind direction.Also,the DV2 spectrum effec-tively characterizes the wind speed and relative azimuth angle dependence for vertically polarized NRCSs.The Elfouhaily spectrum is suitable for simulating vertically polarized NRCSs under conditions of low wind speed(be-low 5 m s^(−1))and incidence angles under 40°.The Kudryavtsev spectrum excels in simulating vertically polarized NRCSs at high incidence angles(>40°)and horizontally polarized NRCSs at low incidence angles(<35°).展开更多
In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to ...In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.展开更多
Driven by advancements in mobile internet technology,images have become a crucial data medium.Ensuring the security of image information during transmission has thus emerged as an urgent challenge.This study proposes ...Driven by advancements in mobile internet technology,images have become a crucial data medium.Ensuring the security of image information during transmission has thus emerged as an urgent challenge.This study proposes a novel image encryption algorithm specifically designed for grayscale image security.This research introduces a new Cantor diagonal matrix permutation method.The proposed permutation method uses row and column index sequences to control the Cantor diagonal matrix,where the row and column index sequences are generated by a spatiotemporal chaotic system named coupled map lattice(CML).The high initial value sensitivity of the CML system makes the permutation method highly sensitive and secure.Additionally,leveraging fractal theory,this study introduces a chaotic fractal matrix and applies this matrix in the diffusion process.This chaotic fractal matrix exhibits selfsimilarity and irregularity.Using the Cantor diagonal matrix and chaotic fractal matrix,this paper introduces a fast image encryption algorithm involving two diffusion steps and one permutation step.Moreover,the algorithm achieves robust security with only a single encryption round,ensuring high operational efficiency.Experimental results show that the proposed algorithm features an expansive key space,robust security,high sensitivity,high efficiency,and superior statistical properties for the ciphered images.Thus,the proposed algorithm not only provides a practical solution for secure image transmission but also bridges fractal theory with image encryption techniques,thereby opening new research avenues in chaotic cryptography and advancing the development of information security technology.展开更多
We read with the great interest the study by Ababneh et al in which inducedmesenchymal stem cell-derived exosomes were shown to exhibit a stronger andmore sustained anti-proliferative effect by inducing a senescence-l...We read with the great interest the study by Ababneh et al in which inducedmesenchymal stem cell-derived exosomes were shown to exhibit a stronger andmore sustained anti-proliferative effect by inducing a senescence-like state withoutapoptosis.The results obtained by the authors highlight the features of theeffects of senescent drift induction in surrounding tissues.In the light of thesefindings,the role of the properties of extracellular matrix and cellular glycocalyxin responses of human tumors to therapy remain uninvestigated.These extracellularbarriers appear to be significant obstacles to effective cancer therapy,especiallyin relation to the use of unique properties of tumor microenvironment forthe immunotherapy-resistant cancer treatment.展开更多
A nonfused ring electron acceptor(NFREA),designated as TT-Ph-C6,has been synthesized with the aim of enhancing the power conversion efficiency(PCE)of organic solar cells(OSCs).By integrating asymmetric phenylalkylamin...A nonfused ring electron acceptor(NFREA),designated as TT-Ph-C6,has been synthesized with the aim of enhancing the power conversion efficiency(PCE)of organic solar cells(OSCs).By integrating asymmetric phenylalkylamino side groups,TT-Ph-C6 demonstrates excellent solubility and its crystal structure exhibits compact packing structures with a three-dimensional molecular stacking network.These structural attributes markedly promote exciton diffusion and charge carrier mobility,particularly advantageous for the fabrication of thick-film devices.TT-Ph-C6-based devices have attained a PCE of 18.01%at a film thickness of 100 nm,and even at a film thickness of 300 nm,the PCE remains at 14.64%,surpassing that of devices based on 2BTh-2F.These remarkable properties position TT-Ph-C6 as a highly promising NFREA material for boosting the efficiency of OSCs.展开更多
Peripheral nerve injury causes severe neuroinflammation and has become a global medical challenge.Previous research has demonstrated that porcine decellularized nerve matrix hydrogel exhibits excellent biological prop...Peripheral nerve injury causes severe neuroinflammation and has become a global medical challenge.Previous research has demonstrated that porcine decellularized nerve matrix hydrogel exhibits excellent biological properties and tissue specificity,highlighting its potential as a biomedical material for the repair of severe peripheral nerve injury;however,its role in modulating neuroinflammation post-peripheral nerve injury remains unknown.Here,we aimed to characterize the anti-inflammatory properties of porcine decellularized nerve matrix hydrogel and their underlying molecular mechanisms.Using peripheral nerve injury model rats treated with porcine decellularized nerve matrix hydrogel,we evaluated structural and functional recovery,macrophage phenotype alteration,specific cytokine expression,and changes in related signaling molecules in vivo.Similar parameters were evaluated in vitro using monocyte/macrophage cell lines stimulated with lipopolysaccharide and cultured on porcine decellularized nerve matrix hydrogel-coated plates in complete medium.These comprehensive analyses revealed that porcine decellularized nerve matrix hydrogel attenuated the activation of excessive inflammation at the early stage of peripheral nerve injury and increased the proportion of the M2 subtype in monocytes/macrophages.Additionally,porcine decellularized nerve matrix hydrogel negatively regulated the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB axis both in vivo and in vitro.Our findings suggest that the efficacious anti-inflammatory properties of porcine decellularized nerve matrix hydrogel induce M2 macrophage polarization via suppression of the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway,providing new insights into the therapeutic mechanism of porcine decellularized nerve matrix hydrogel in peripheral nerve injury.展开更多
Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protei...Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protein 4(HE4),a key diagnostic biomarker for ovarian cancer,is involved in fibrotic processes in several non-malignant diseases.Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis,this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC.Methods:A total of 126 patients with gynecological conditions were included and divided into normal,benign,and EOC groups.Tissue stiffness was quantitatively measured and analyzed for its correlation with clinicopathological features.We further investigated the correlation between tumor stiffness and the expression levels of HE4 and fibroblast activation markers(α-smooth muscle actin(α-SMA)and fibroblast activation protein(FAP))in tumor tissues from 22 HGSOC patients.In vitro,primary fibroblasts were treated with recombinant HE4(rHE4)or conditioned media from HE4-knockdown ovarian cancer cells to assess fibroblasts activation and matrix contractility(Collagen gel contraction assays).In vivo,a subcutaneous xenograft model using HE4-knockdown cells was established to evaluate the effects of HE4 suppression on tumor growth and extensive extracellular matrix(ECM)remodeling.Results:Ovarian cancer tissues showed significantly increased stiffness compared to benign/normal groups,showing positive correlation with serum HE4 levels.High-stiffness HGSOC tumors exhibited upregulated expression of HE4,α-SMA,FAP,and collagen I.rHE4 stimulated fibroblast activation and enhanced matrix contractility,whereas HE4 knockdown in cancer cells abrogated these pro-fibrotic effects.In vivo,HE4-silenced xenografts displayed restricted tumor growth accompanied by reduced stromal expression ofα-SMA,FAP,and collagen I.Conclusion:Our findings suggest that HE4 may facilitate ECM remodeling in HGSOC through promoting fibroblast activation and increasing collagen deposition.展开更多
We consider the sufficient and necessary conditions for the formal triangular matrix ring being right minsymmetric, right DS, semicommutative, respectively.
An element a of a ring R is called uniquely strongly clean if it is the sum of an idempotent and a unit that commute, and in addition, this expression is unique. R is called uniquely strongly clean if every element of...An element a of a ring R is called uniquely strongly clean if it is the sum of an idempotent and a unit that commute, and in addition, this expression is unique. R is called uniquely strongly clean if every element of R is uniquely strongly clean. The uniquely strong cleanness of the triangular matrix ring is studied. Let R be a local ring. It is shown that any n × n upper triangular matrix ring over R is uniquely strongly clean if and only if R is uniquely bleached and R/J（R） ≈Z2.展开更多
In this paper we study Gorenstein(semiheredity)heredity,finite presentedness and F P-injectivity of modules over a formal triangular matrix ring.We provide necessary and sufficient conditions for such rings to be Gore...In this paper we study Gorenstein(semiheredity)heredity,finite presentedness and F P-injectivity of modules over a formal triangular matrix ring.We provide necessary and sufficient conditions for such rings to be Gorenstein(semihereditary)hereditary and investigate when a triangular matrix ring is an n-FC ring.展开更多
The main pathophysiology of cerebral ischemia is the structural alteration in the neurovascular unit, coinciding with neurovascular matrix degradation. Resveratrol has been reported to be one of the most potent chemop...The main pathophysiology of cerebral ischemia is the structural alteration in the neurovascular unit, coinciding with neurovascular matrix degradation. Resveratrol has been reported to be one of the most potent chemopreventive agents that can inhibit cellular processes associated with ischemic stroke. Matrix metalloproteinases （MMPs） has been considered as a potential drug target for the treatment of cerebral ischemia. To explore this, we tried to investigate the inter-action of resveratrol with MMPs through molecular docking studies. At 30 minutes before and 2 hours after cerebral ischemia/reperfusion induced by occlusion of the middle cerebral artery, 40 mg/kg resveratrol was intraperitoneally administered. After resveratrol administration, neu-rological function and brain edema were significantly alleviated, cerebral infarct volume was signiifcantly reduced, and nitrite and malondialdehyde levels in the cortical and striatal regions were signiifcantly decreased. The molecular docking study of resveratrol and MMPs revealed that resveratrol occupied the active site of MMP-2 and MMP-9. The binding energy of the complexes was –37.848672 kJ/mol and –36.6345 kJ/mol for MMP-2 and MMP-9, respectively. In case of MMP-2, Leu 164, Ala 165 and Thr 227 were engaged in H-Bonding with resveratrol and in case of MMP-9, H-bonding was found with Glu 402, Ala 417 and Arg 424 residues. These ifndings collectively reveal that resveratrol exhibits neuroprotective effects on cerebral ischemia through inhibiting MMP-2 and MMP-9 activity.展开更多
In this paper we study the formal triangular matrix ring T =and give some necessary and sufficient conditions for T to be (strongly) separative, m-fold stable and unit 1-stable. Moreover, a condition for finitely gene...In this paper we study the formal triangular matrix ring T =and give some necessary and sufficient conditions for T to be (strongly) separative, m-fold stable and unit 1-stable. Moreover, a condition for finitely generated projec-tive T-modules to have n in the stable range is given under the assumption that A and B are exchange rings.展开更多
Let R and S be rings with identity, M be a unitary（R, S）-bimodule and T =（R M0 S）be the upper triangular matrix ring determined by R, S and M. In this paper we prove that under certain conditions a Jordan bideriva...Let R and S be rings with identity, M be a unitary（R, S）-bimodule and T =（R M0 S）be the upper triangular matrix ring determined by R, S and M. In this paper we prove that under certain conditions a Jordan biderivation of an upper triangular matrix ring T is a biderivation of T.展开更多
Due to the non-stationary characteristics of vibration signals acquired from rolling element bearing fault, thc time-frequency analysis is often applied to describe the local information of these unstable signals smar...Due to the non-stationary characteristics of vibration signals acquired from rolling element bearing fault, thc time-frequency analysis is often applied to describe the local information of these unstable signals smartly. However, it is difficult to classitythe high dimensional feature matrix directly because of too large dimensions for many classifiers. This paper combines the concepts of time-frequency distribution（TFD） with non-negative matrix factorization（NMF）, and proposes a novel TFD matrix factorization method to enhance representation and identification of bearing fault. Throughout this method, the TFD of a vibration signal is firstly accomplished to describe the localized faults with short-time Fourier transform（STFT）. Then, the supervised NMF mapping is adopted to extract the fault features from TFD. Meanwhile, the fault samples can be clustered and recognized automatically by using the clustering property of NMF. The proposed method takes advantages of the NMF in the parts-based representation and the adaptive clustering. The localized fault features of interest can be extracted as well. To evaluate the performance of the proposed method, the 9 kinds of the bearing fault on a test bench is performed. The proposed method can effectively identify the fault severity and different fault types. Moreover, in comparison with the artificial neural network（ANN）, NMF yields 99.3% mean accuracy which is much superior to ANN. This research presents a simple and practical resolution for the fault diagnosis problem of rolling element bearing in high dimensional feature space.展开更多
Pseudopolar rings are closely related to strongly -regular rings, uniquelystrongly clean rings and semiregular rings. In this paper, we investigate pseudopolar-ity of generalized matrix rings Ks（R） over a local ring...Pseudopolar rings are closely related to strongly -regular rings, uniquelystrongly clean rings and semiregular rings. In this paper, we investigate pseudopolar-ity of generalized matrix rings Ks（R） over a local ring R. We determine the conditionsunder which elements of Ks（R） are pseudopolar. Assume that R is a local ring. It isshown that A ∈ Ks（R） is pseudopolar if and only if A is invertible or A^2 ∈ J（Ks（R））or A is similar to a diagonal matrix [ u 0 0 j ]; where lu -rj and lj-ru are injectiveand u 2 U（R） and j ∈ J（R）. Furthermore, several equivalent conditions for Ks（R）over a local ring R to be pseudopolar are obtained.展开更多
Hybrid aluminum matrix composite powders reinforced with bimodal-sized Al2O3 particles were synthesized by mechanical milling.Two different approaches were investigated for the addition of submicron-and nano-sized Al2...Hybrid aluminum matrix composite powders reinforced with bimodal-sized Al2O3 particles were synthesized by mechanical milling.Two different approaches were investigated for the addition of submicron-and nano-sized Al2O3 particles to the aluminum powders,It was observed that the simultaneous addition of bimodal-sized Al2O3 particles to the aluminum powders resulted in an equiaxed morphology of the composite powders and the average particle size stabilized after 5 h of milling,indicating that the presence of bimodal-sized particles has greater effect on accelerating milling process as compared to nano-sized particles;the grain size of the aluminum matrix in composite powders was reduced to under 40 nm,approximate to the value obtained in the separate addition case,while a lower rate of refining was observed due to hindrance of submicron-sized particles on the interactions between nano-sized particles and the aluminum matrix.展开更多
文摘This study introduces a comprehensive theoretical framework for accurately calculating the electronic band-structure of strained long-wavelength InAs/GaSb type-Ⅱsuperlattices.Utilizing an eight-band k·p Hamilto⁃nian in conjunction with a scattering matrix method,the model effectively incorporates quantum confinement,strain effects,and interface states.This robust and numerically stable approach achieves exceptional agreement with experimental data,offering a reliable tool for analyzing and engineering the band structure of complex multi⁃layer systems.
基金supported by National Natural Science Foundation of China(Grant No.52305419)Aeronautical Science Foundation Funded by Chinese Aeronautical Establishment(Grant No.2022Z0490T6001)+5 种基金Research Start-up Project of Xi’an University of Technology(Grant No.101-256082204)Technology Foundation for Selected Overseas Chinese Scholar(Grant No.2023-010)International Science and Technology Cooperation Program of Shaanxi Province(Grant No.2023-GHZD-50)Projects of Major Innovation Platforms for Scientific and Technological and Local Transformation of Scientific and Technological Achievements of Xi’an(Grant No.20GXSF0003)Higher Education Institution Discipline Innovation and Intelligence Base of Shaanxi Provincial(Grant No.S2021-ZCGXYZ-0011)Natural Science Basic Research Program of Shaanxi(Grant No.2023-JC-YB-412).
文摘Hetero-deformation induced(HDI) strengthening generally yields a weak effect on the mechanical property improvement of particle-reinforced metal matrix composites(MMCs). In the present work, a novel strategy was reported to induce remarkable HDI strengthening in MMCs by selecting a reinforcing material with excellent geometrically necessary dislocation(GND) storage ability. The viability of the proposed strategy was tested on additively manufactured nickel matrix composites consisting of Inconel 625 alloy(IN625) as the matrix and high-entropy alloy VNbMoTa as the reinforcing material. It was found that the average grain size and dislocation density of the additively manufactured MMCs gradually decreased with the increase in the additional amount of VNbMoTa. All the samples possessed a similar two-layer VNbMoTa-matrix interface structure containing a high-entropy alloy layer and a Laves phase layer;however, the interface width varied. This two-layer interface could hold GND pile-ups without breaking to ensure a good load transfer effect, and ductile VNbMoTa particles demonstrated excellent GND storage capacity to induce significant HDI stress. The HDI stress for the IN625-(10 wt%)VNbMoTa sample was approximately 200 MPa higher than that for the pure IN625 alloy, resulting in an excellent strength-ductility synergy. The yield strength and elongation of the IN625-(10 wt%)VNbMoTa sample reached(1 032.5 ± 18.8)MPa and(11.8 ± 1.2)%, respectively. In addition, the IN625-(10 wt%)VNbMoTa composite also demonstrated superior mechanical properties at 650℃ that were comparable to those at room temperature, implying that VNbMoTa addition remarkably limited strength reduction caused by temperature. Deformable VNbMoTa particles effectively alleviated the stress concentration, delayed the crack initiation, generated more dislocations and pile-ups, and, in turn, improved the overall high-temperature strength of composites.
基金funded by the National Key Research and Development Program[grant number 2022YFC3004200]the National Natural Science Foundation of China[grant number U2142212]the Hunan Provincial Natural Science Foundation of China[grant number 2021JC0009]。
文摘A polarized bidirectional reflectance distribution function(pBRDF)matrix is developed from two-scale roughness theory with the aim of providing more accurate simulations of microwave emissions and scattering required for ocean-atmosphere coupled radiative transfer models.The potential of the pBRDF matrix is explored for simu-lating the ocean backscatter at Ku-band.The effects of ocean wave spectra including the modified Durden and Vesecky(DV2),Elfouhaily,and Kudryavtsev spectra on the pBRDF matrix backscatter simulations are investi-gated.Additionally,the differences in backscattering normalized radar cross-section(NRCS)simulations between the Ku-band geophysical model function and pBRDF matrix are analyzed.The results show that the pBRDF matrix can reasonably reproduce the spatial distribution of ocean surface backscattering energy,but the distribution pat-tern and numerical values are influenced by ocean wave spectra.The DV2 spectrum is the best one for the pBRDF matrix to simulate horizontally polarized NRCSs,with the exception of scenarios where the incidence angle is below 35°,the wind speed is less than 10 m s^(−1),and in the cross-wind direction.Also,the DV2 spectrum effec-tively characterizes the wind speed and relative azimuth angle dependence for vertically polarized NRCSs.The Elfouhaily spectrum is suitable for simulating vertically polarized NRCSs under conditions of low wind speed(be-low 5 m s^(−1))and incidence angles under 40°.The Kudryavtsev spectrum excels in simulating vertically polarized NRCSs at high incidence angles(>40°)and horizontally polarized NRCSs at low incidence angles(<35°).
基金Supported in part by Natural Science Foundation of Guangxi(2023GXNSFAA026246)in part by the Central Government's Guide to Local Science and Technology Development Fund(GuikeZY23055044)in part by the National Natural Science Foundation of China(62363003)。
文摘In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.
基金supported by the National Natural Science Foundation of China(62376106)The Science and Technology Development Plan of Jilin Province(20250102212JC).
文摘Driven by advancements in mobile internet technology,images have become a crucial data medium.Ensuring the security of image information during transmission has thus emerged as an urgent challenge.This study proposes a novel image encryption algorithm specifically designed for grayscale image security.This research introduces a new Cantor diagonal matrix permutation method.The proposed permutation method uses row and column index sequences to control the Cantor diagonal matrix,where the row and column index sequences are generated by a spatiotemporal chaotic system named coupled map lattice(CML).The high initial value sensitivity of the CML system makes the permutation method highly sensitive and secure.Additionally,leveraging fractal theory,this study introduces a chaotic fractal matrix and applies this matrix in the diffusion process.This chaotic fractal matrix exhibits selfsimilarity and irregularity.Using the Cantor diagonal matrix and chaotic fractal matrix,this paper introduces a fast image encryption algorithm involving two diffusion steps and one permutation step.Moreover,the algorithm achieves robust security with only a single encryption round,ensuring high operational efficiency.Experimental results show that the proposed algorithm features an expansive key space,robust security,high sensitivity,high efficiency,and superior statistical properties for the ciphered images.Thus,the proposed algorithm not only provides a practical solution for secure image transmission but also bridges fractal theory with image encryption techniques,thereby opening new research avenues in chaotic cryptography and advancing the development of information security technology.
文摘We read with the great interest the study by Ababneh et al in which inducedmesenchymal stem cell-derived exosomes were shown to exhibit a stronger andmore sustained anti-proliferative effect by inducing a senescence-like state withoutapoptosis.The results obtained by the authors highlight the features of theeffects of senescent drift induction in surrounding tissues.In the light of thesefindings,the role of the properties of extracellular matrix and cellular glycocalyxin responses of human tumors to therapy remain uninvestigated.These extracellularbarriers appear to be significant obstacles to effective cancer therapy,especiallyin relation to the use of unique properties of tumor microenvironment forthe immunotherapy-resistant cancer treatment.
基金Financial support from the National Natural Science Foundation of China(22375024,21975031,21734009,51933001,22109080,and 52173174)the Natural Science Foundation of Shandong Province(No.ZR2022YQ45)+2 种基金the Taishan Scholars Program(Nos.tstp20221121 and tsqnz20221134)The Beijing Natural Science Foundation(No.2244073)supported by State Key Laboratory of Bio-Fibers and Eco-Textiles(Qingdao University)(RZ2200002821)is acknowledged.
文摘A nonfused ring electron acceptor(NFREA),designated as TT-Ph-C6,has been synthesized with the aim of enhancing the power conversion efficiency(PCE)of organic solar cells(OSCs).By integrating asymmetric phenylalkylamino side groups,TT-Ph-C6 demonstrates excellent solubility and its crystal structure exhibits compact packing structures with a three-dimensional molecular stacking network.These structural attributes markedly promote exciton diffusion and charge carrier mobility,particularly advantageous for the fabrication of thick-film devices.TT-Ph-C6-based devices have attained a PCE of 18.01%at a film thickness of 100 nm,and even at a film thickness of 300 nm,the PCE remains at 14.64%,surpassing that of devices based on 2BTh-2F.These remarkable properties position TT-Ph-C6 as a highly promising NFREA material for boosting the efficiency of OSCs.
基金supported by the Shenzhen Hong Kong Joint Funding Project,No.SGDX20230116093645007(to LY)the Shenzhen Science and Technology Innovation Committee International Cooperation Project,No.GJHZ20200731095608025(to LY)+7 种基金Shenzhen Development and Reform Commission’s Intelligent Diagnosis,Treatment and Prevention of Adolescent Spinal Health Public Service Platform,No.S2002Q84500835(to LY)Shenzhen Medical Research Fund,No.B2303005(to LY)Team-based Medical Science Research Program,No.2024YZZ02(to LY)Zhejiang Provincial Natural Science Foundation of China,No.LWQ20H170001(to RL)Basic Research Project of Shenzhen Science and Technology from Shenzhen Science and Technology Innovation Commission,No.JCYJ20210324103010029(to BY)Shenzhen Second People’s Hospital Clinical Research Fund of Guangdong Province High-level Hospital Construction Project,Nos.2023yjlcyj029(to BY),2023yjlcyj021(to LL)Guangdong Basic and Applied Basic Research Foundation,No.2022A1515110679(to LL)China Postdoctoral Science Foundation,No.2022M722203(to GL).
文摘Peripheral nerve injury causes severe neuroinflammation and has become a global medical challenge.Previous research has demonstrated that porcine decellularized nerve matrix hydrogel exhibits excellent biological properties and tissue specificity,highlighting its potential as a biomedical material for the repair of severe peripheral nerve injury;however,its role in modulating neuroinflammation post-peripheral nerve injury remains unknown.Here,we aimed to characterize the anti-inflammatory properties of porcine decellularized nerve matrix hydrogel and their underlying molecular mechanisms.Using peripheral nerve injury model rats treated with porcine decellularized nerve matrix hydrogel,we evaluated structural and functional recovery,macrophage phenotype alteration,specific cytokine expression,and changes in related signaling molecules in vivo.Similar parameters were evaluated in vitro using monocyte/macrophage cell lines stimulated with lipopolysaccharide and cultured on porcine decellularized nerve matrix hydrogel-coated plates in complete medium.These comprehensive analyses revealed that porcine decellularized nerve matrix hydrogel attenuated the activation of excessive inflammation at the early stage of peripheral nerve injury and increased the proportion of the M2 subtype in monocytes/macrophages.Additionally,porcine decellularized nerve matrix hydrogel negatively regulated the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB axis both in vivo and in vitro.Our findings suggest that the efficacious anti-inflammatory properties of porcine decellularized nerve matrix hydrogel induce M2 macrophage polarization via suppression of the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway,providing new insights into the therapeutic mechanism of porcine decellularized nerve matrix hydrogel in peripheral nerve injury.
文摘Objectives:High-grade serous ovarian cancer(HGSOC),the most common subtype of epithelial ovarian cancer(EOC),exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis.Human epididymis protein 4(HE4),a key diagnostic biomarker for ovarian cancer,is involved in fibrotic processes in several non-malignant diseases.Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis,this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC.Methods:A total of 126 patients with gynecological conditions were included and divided into normal,benign,and EOC groups.Tissue stiffness was quantitatively measured and analyzed for its correlation with clinicopathological features.We further investigated the correlation between tumor stiffness and the expression levels of HE4 and fibroblast activation markers(α-smooth muscle actin(α-SMA)and fibroblast activation protein(FAP))in tumor tissues from 22 HGSOC patients.In vitro,primary fibroblasts were treated with recombinant HE4(rHE4)or conditioned media from HE4-knockdown ovarian cancer cells to assess fibroblasts activation and matrix contractility(Collagen gel contraction assays).In vivo,a subcutaneous xenograft model using HE4-knockdown cells was established to evaluate the effects of HE4 suppression on tumor growth and extensive extracellular matrix(ECM)remodeling.Results:Ovarian cancer tissues showed significantly increased stiffness compared to benign/normal groups,showing positive correlation with serum HE4 levels.High-stiffness HGSOC tumors exhibited upregulated expression of HE4,α-SMA,FAP,and collagen I.rHE4 stimulated fibroblast activation and enhanced matrix contractility,whereas HE4 knockdown in cancer cells abrogated these pro-fibrotic effects.In vivo,HE4-silenced xenografts displayed restricted tumor growth accompanied by reduced stromal expression ofα-SMA,FAP,and collagen I.Conclusion:Our findings suggest that HE4 may facilitate ECM remodeling in HGSOC through promoting fibroblast activation and increasing collagen deposition.
基金Foundation item： Supported by the Fund of Beijing Education Committee（KM200610005024） Supported by the National Natural Science Foundation of China（10671061）
文摘We consider the sufficient and necessary conditions for the formal triangular matrix ring being right minsymmetric, right DS, semicommutative, respectively.
基金The National Natural Science Foundation of China(No.10971024)the Specialized Research Fund for the Doctoral Program of Higher Education(No.200802860024)the Natural Science Foundation of Jiangsu Province(No.BK2010393)
文摘An element a of a ring R is called uniquely strongly clean if it is the sum of an idempotent and a unit that commute, and in addition, this expression is unique. R is called uniquely strongly clean if every element of R is uniquely strongly clean. The uniquely strong cleanness of the triangular matrix ring is studied. Let R be a local ring. It is shown that any n × n upper triangular matrix ring over R is uniquely strongly clean if and only if R is uniquely bleached and R/J（R） ≈Z2.
基金Supported by the National Natural Science Foundation of China(Grant No.11671126)。
文摘In this paper we study Gorenstein(semiheredity)heredity,finite presentedness and F P-injectivity of modules over a formal triangular matrix ring.We provide necessary and sufficient conditions for such rings to be Gorenstein(semihereditary)hereditary and investigate when a triangular matrix ring is an n-FC ring.
文摘The main pathophysiology of cerebral ischemia is the structural alteration in the neurovascular unit, coinciding with neurovascular matrix degradation. Resveratrol has been reported to be one of the most potent chemopreventive agents that can inhibit cellular processes associated with ischemic stroke. Matrix metalloproteinases （MMPs） has been considered as a potential drug target for the treatment of cerebral ischemia. To explore this, we tried to investigate the inter-action of resveratrol with MMPs through molecular docking studies. At 30 minutes before and 2 hours after cerebral ischemia/reperfusion induced by occlusion of the middle cerebral artery, 40 mg/kg resveratrol was intraperitoneally administered. After resveratrol administration, neu-rological function and brain edema were significantly alleviated, cerebral infarct volume was signiifcantly reduced, and nitrite and malondialdehyde levels in the cortical and striatal regions were signiifcantly decreased. The molecular docking study of resveratrol and MMPs revealed that resveratrol occupied the active site of MMP-2 and MMP-9. The binding energy of the complexes was –37.848672 kJ/mol and –36.6345 kJ/mol for MMP-2 and MMP-9, respectively. In case of MMP-2, Leu 164, Ala 165 and Thr 227 were engaged in H-Bonding with resveratrol and in case of MMP-9, H-bonding was found with Glu 402, Ala 417 and Arg 424 residues. These ifndings collectively reveal that resveratrol exhibits neuroprotective effects on cerebral ischemia through inhibiting MMP-2 and MMP-9 activity.
文摘In this paper we study the formal triangular matrix ring T =and give some necessary and sufficient conditions for T to be (strongly) separative, m-fold stable and unit 1-stable. Moreover, a condition for finitely generated projec-tive T-modules to have n in the stable range is given under the assumption that A and B are exchange rings.
文摘Let R and S be rings with identity, M be a unitary（R, S）-bimodule and T =（R M0 S）be the upper triangular matrix ring determined by R, S and M. In this paper we prove that under certain conditions a Jordan biderivation of an upper triangular matrix ring T is a biderivation of T.
基金Supported by Shaanxi Provincial Overall Innovation Project of Science and Technology,China(Grant No.2013KTCQ01-06)
文摘Due to the non-stationary characteristics of vibration signals acquired from rolling element bearing fault, thc time-frequency analysis is often applied to describe the local information of these unstable signals smartly. However, it is difficult to classitythe high dimensional feature matrix directly because of too large dimensions for many classifiers. This paper combines the concepts of time-frequency distribution（TFD） with non-negative matrix factorization（NMF）, and proposes a novel TFD matrix factorization method to enhance representation and identification of bearing fault. Throughout this method, the TFD of a vibration signal is firstly accomplished to describe the localized faults with short-time Fourier transform（STFT）. Then, the supervised NMF mapping is adopted to extract the fault features from TFD. Meanwhile, the fault samples can be clustered and recognized automatically by using the clustering property of NMF. The proposed method takes advantages of the NMF in the parts-based representation and the adaptive clustering. The localized fault features of interest can be extracted as well. To evaluate the performance of the proposed method, the 9 kinds of the bearing fault on a test bench is performed. The proposed method can effectively identify the fault severity and different fault types. Moreover, in comparison with the artificial neural network（ANN）, NMF yields 99.3% mean accuracy which is much superior to ANN. This research presents a simple and practical resolution for the fault diagnosis problem of rolling element bearing in high dimensional feature space.
文摘Pseudopolar rings are closely related to strongly -regular rings, uniquelystrongly clean rings and semiregular rings. In this paper, we investigate pseudopolar-ity of generalized matrix rings Ks（R） over a local ring R. We determine the conditionsunder which elements of Ks（R） are pseudopolar. Assume that R is a local ring. It isshown that A ∈ Ks（R） is pseudopolar if and only if A is invertible or A^2 ∈ J（Ks（R））or A is similar to a diagonal matrix [ u 0 0 j ]; where lu -rj and lj-ru are injectiveand u 2 U（R） and j ∈ J（R）. Furthermore, several equivalent conditions for Ks（R）over a local ring R to be pseudopolar are obtained.
基金the financial support from the State Key Laboratory of Traction Power(Grant No.2015TPL_Z01)the State Key Laboratory of Solidification Processing(Grant Nos.82-TZ-2013 and SKLSP201609)+1 种基金the Fundamental Research Funds for the Central Universities(Grant No.2682017CX090)the‘‘111’’Project(B08040)
文摘Hybrid aluminum matrix composite powders reinforced with bimodal-sized Al2O3 particles were synthesized by mechanical milling.Two different approaches were investigated for the addition of submicron-and nano-sized Al2O3 particles to the aluminum powders,It was observed that the simultaneous addition of bimodal-sized Al2O3 particles to the aluminum powders resulted in an equiaxed morphology of the composite powders and the average particle size stabilized after 5 h of milling,indicating that the presence of bimodal-sized particles has greater effect on accelerating milling process as compared to nano-sized particles;the grain size of the aluminum matrix in composite powders was reduced to under 40 nm,approximate to the value obtained in the separate addition case,while a lower rate of refining was observed due to hindrance of submicron-sized particles on the interactions between nano-sized particles and the aluminum matrix.
