In this paper, we characterize lower semi-continuous pseudo-convex functions f : X → R ∪ {+ ∞} on convex subset of real Banach spaces K ⊂ X with respect to the pseudo-monotonicity of its Clarke-Rockafellar Su...In this paper, we characterize lower semi-continuous pseudo-convex functions f : X → R ∪ {+ ∞} on convex subset of real Banach spaces K ⊂ X with respect to the pseudo-monotonicity of its Clarke-Rockafellar Sub-differential. We extend the results on the characterizations of non-smooth convex functions f : X → R ∪ {+ ∞} on convex subset of real Banach spaces K ⊂ X with respect to the monotonicity of its sub-differentials to the lower semi-continuous pseudo-convex functions on real Banach spaces.展开更多
Objective:To evaluate the effect of task-oriented training combined with a lower limb rehabilitation robot on improving motor function and ankle joint function in stroke patients with hemiplegia.Methods:Sixty-three st...Objective:To evaluate the effect of task-oriented training combined with a lower limb rehabilitation robot on improving motor function and ankle joint function in stroke patients with hemiplegia.Methods:Sixty-three stroke patients with hemiplegia admitted to our hospital from January 2022 to June 2024 were randomly divided into observation group(32 cases)and control group(31 cases)using the envelope method.The control group received task-oriented training,while the observation group received additional lower limb rehabilitation robot training.The motor function(Fugl-Meyer Assessment of Lower Extremity,FMA-LE)and ankle joint function(Active Dorsiflexion Range of Motion,DF AROM)were compared between the two groups.Results:After treatment,the levels of FMA-LE and DF AROM in both groups increased significantly,and the improvement in each index in the observation group was better than that in the control group(P<0.05).Conclusion:The combination of task-oriented training and lower limb rehabilitation robot training can more effectively improve the overall motor function of the lower limbs and the active dorsiflexion ability of the ankle joint in stroke patients with hemiplegia.展开更多
The purpose of this paper is to make a further study on the abstract economy. Here, for the constraint correspondences we assume that they are almost lower semi-continuous (n-lower semi-continuous), which is weaken th...The purpose of this paper is to make a further study on the abstract economy. Here, for the constraint correspondences we assume that they are almost lower semi-continuous (n-lower semi-continuous), which is weaken than that they are lower semi-continuous. Several equilibria existence theorems are proved.展开更多
Transcranial magnetic stimulation,a type of noninvasive brain stimulation,has become an ancillary therapy for motor function rehabilitation.Most previous studies have focused on the effects of repetitive transcranial ...Transcranial magnetic stimulation,a type of noninvasive brain stimulation,has become an ancillary therapy for motor function rehabilitation.Most previous studies have focused on the effects of repetitive transcranial magnetic stimulation(rTMS)on motor function in stroke patients.There have been relatively few studies on the effects of different modalities of rTMS on lower extremity motor function and corticospinal excitability in patients with stroke.The MEDLINE,Embase,Cochrane Library,ISI Science Citation Index,Physiotherapy Evidence Database,China National Knowledge Infrastructure Library,and ClinicalTrials.gov databases were searched.Parallel or crossover randomized controlled trials that addressed the effectiveness of rTMS in patients with stroke,published from inception to November 28,2019,were included.Standard pairwise meta-analysis was conducted using R version 3.6.1 with the“meta”package.Bayesian network analysis using the Markov chain Monte Carlo algorithm was conducted to investigate the effectiveness of different rTMS protocol interventions.Network meta-analysis results of 18 randomized controlled trials regarding lower extremity motor function recovery revealed that low-frequency rTMS had better efficacy in promoting lower extremity motor function recovery than sham stimulation.Network meta-analysis results of five randomized controlled trials demonstrated that highfrequency rTMS led to higher amplitudes of motor evoked potentials than low-frequency rTMS or sham stimulation.These findings suggest that rTMS can improve motor function in patients with stroke,and that low-frequency rTMS mainly affects motor function,whereas high-frequency rTMS increases the amplitudes of motor evoked potentials.More highquality randomized controlled trials are needed to validate this conclusion.The work was registered in PROSPERO(registration No.CRD42020147055)on April 28,2020.展开更多
The main objective is to derive a lower bound from an upper one for harmonic functions in the half space, which extends a result of B. Y. Levin from dimension 2 to dimension n 〉 2. To this end, we first generalize th...The main objective is to derive a lower bound from an upper one for harmonic functions in the half space, which extends a result of B. Y. Levin from dimension 2 to dimension n 〉 2. To this end, we first generalize the Carleman＇s formula for harmonic functions in the half plane to higher dimensional half space, and then establish a Nevanlinna＇s representation for harmonic functions in the half sphere by using HSrmander＇s theorem.展开更多
This study investigated the correlation between periprostatic fat thickness(PPFT)measured on magnetic resonance imaging and lower urinary tract symptoms,erectile function,and benign prostatic hyperplasia(BPH)progressi...This study investigated the correlation between periprostatic fat thickness(PPFT)measured on magnetic resonance imaging and lower urinary tract symptoms,erectile function,and benign prostatic hyperplasia(BPH)progression.A total of 286 treatment-naive men diagnosed with BPH in our department between March 2017 and February 2019 were included.Patients were divided into two groups according to the median value of PPFT:high(PPFT>4.35 mm)PPFT group and low(PPFT<4.35 mm)PPFT group.After the initial evaluation,all patients received a combination drug treatment of tamsulosin and finasteride for 12 months.Of the 286 enrolled patients,244 completed the drug treatment course.Patients with high PPFT had larger prostate volume(PV;P=0.013),higher International Prostate Symptom Score(IPSS;P-0.008),and lower five-item version of the International Index of Erectile Function(IIEF-5)score(P=0.002)than those with low PPFT.Both high and low PPFT groups showed significant improvements in PV,maximum flow rate,IPSS,and quality of life score and a decrease of IIEF-5 score after the combination drug treatment.The decrease of IIEF-5 score was more obvious in the high PPFT group than that in the low PPFT group.In addition,more patients in the high PPFT group underwent prostate surgery than those in the low PPFT group.Moreover,Pearson’s correlation coefficient analysis indicated that PPFT was positively correlated with age,PV,and IPSS and negatively correlated with IIEF-5 score;however,body mass index was only negatively correlated with IIEF-5 score.展开更多
The relationship between acute high altitude response (AHAR), cardiac function injury, and high altitude de-adaptation response (HADAR) was assessed. Cardiac function indicators were assessed for 96 men (18 - 35 years...The relationship between acute high altitude response (AHAR), cardiac function injury, and high altitude de-adaptation response (HADAR) was assessed. Cardiac function indicators were assessed for 96 men (18 - 35 years old) deployed into a high altitude (3700 - 4800 m) environment requiring intense physical activity. The subjects were divided into 3 groups based on AHAR at high altitude: severe AHAR (n = 24), mild to moderate AHAR (Group B, n = 47) and non-AHAR (Group C, 25);and based on HADAR: severe HADAR (Group E, n = 19), mild to moderate HADAR (Group F, n = 40) and non-HADAR (Group G, n = 37) after return to lower altitude (1,500 m). Cardiac function indicators were measured after 50 days at high altitude and at 12 h, 15 days, and 30 days after return to lower altitude. Controls were 50 healthy volunteers (Group D, n = 50) at 1500 m. Significant differences were observed in cardiac function indicators among groups A, B, C, and D. AHAR score was positively correlated with HADAR score (r = 0.863, P < 0.001). Significant differ- ences were also observed in cardiac function indicators among groups D, E, F, and G, 12 h and15 days after return to lower altitude. There were no significant differences in cardiac function indicators among the groups, 30 days after return to lower altitude, compared to group D. The results indicated that the severity of HADAR is associated with the severity of AHAR and cardiac injury, and prolonged recovery.展开更多
Functional electrical stimulation is a method of repairing a dysfunctional limb in a stroke patient by using low-intensity electrical stimulation.Currently,it is widely used in smart medical treatment for limb rehabil...Functional electrical stimulation is a method of repairing a dysfunctional limb in a stroke patient by using low-intensity electrical stimulation.Currently,it is widely used in smart medical treatment for limb rehabilitation in stroke patients.In this paper,the development of FES systems is sorted out and analyzed in a time order.Then,the progress of functional electrical stimulation in the field of rehabilitation is reviewed in details in two aspects,i.e.,system development and algorithm progress.In the system aspect,the development of the first FES control and stimulation system,the core of the lower limb-based neuroprosthesis system and the system based on brain-computer interface are introduced.The algorithm optimization for control strategy is introduced in the algorithm.Asynchronous stimulation to prolong the function time of the lower limbs and a method to improve the robustness of knee joint modeling using neural networks.Representative applications in each of these aspects have been investigated and analyzed.展开更多
In this study,precise control over the thickness and termination of Ti3C2TX MXene flakes is achieved to enhance their electrical properties,environmental stability,and gas-sensing performance.Utilizing a hybrid method...In this study,precise control over the thickness and termination of Ti3C2TX MXene flakes is achieved to enhance their electrical properties,environmental stability,and gas-sensing performance.Utilizing a hybrid method involving high-pressure processing,stirring,and immiscible solutions,sub-100 nm MXene flake thickness is achieved within the MXene film on the Si-wafer.Functionalization control is achieved by defunctionalizing MXene at 650℃ under vacuum and H2 gas in a CVD furnace,followed by refunctionalization with iodine and bromine vaporization from a bubbler attached to the CVD.Notably,the introduction of iodine,which has a larger atomic size,lower electronegativity,reduce shielding effect,and lower hydrophilicity(contact angle:99°),profoundly affecting MXene.It improves the surface area(36.2 cm^(2) g^(-1)),oxidation stability in aqueous/ambient environments(21 days/80 days),and film conductivity(749 S m^(-1)).Additionally,it significantly enhances the gas-sensing performance,including the sensitivity(0.1119Ωppm^(-1)),response(0.2% and 23%to 50 ppb and 200 ppm NO_(2)),and response/recovery times(90/100 s).The reduced shielding effect of the–I-terminals and the metallic characteristics of MXene enhance the selectivity of I-MXene toward NO2.This approach paves the way for the development of stable and high-performance gas-sensing two-dimensional materials with promising prospects for future studies.展开更多
In this paper lower semicontinuity of the functional I(u)=∫_Ωf(x,u,Δ~ _Hu)dx is investigated for f being a Carathéodory function defined on Hn×R×R^2n and for u∈SBV_H(Ω),where Hn is the Heisenberg g...In this paper lower semicontinuity of the functional I(u)=∫_Ωf(x,u,Δ~ _Hu)dx is investigated for f being a Carathéodory function defined on Hn×R×R^2n and for u∈SBV_H(Ω),where Hn is the Heisenberg group with dimension 2n+1,ΩHn is an open set and Δ~ _Hu denotes the approximate derivative of the absolute continuous part Da_Hu with respect to D_Hu.In addition,a Lusin type approximation theorem for a SBV_H function is proved.展开更多
Treatment of skeletal Cl II includes functional orthopedic treatment, head-gears, extraction of the upper premolars and orthognathic surgery. To treat any patient with functional appliances (bite jumping) an adequate ...Treatment of skeletal Cl II includes functional orthopedic treatment, head-gears, extraction of the upper premolars and orthognathic surgery. To treat any patient with functional appliances (bite jumping) an adequate overjet is necessary. In this case an 11 years old female patient has skeletal CLII due to mandibular deficiency with ANB angle 8 degrees, overbite: 3 mm, overjet: 1 mm, extremely convex profile and underdeveloped chin due to the hyper muscle contraction of the lower lip to obtain oral seal. To obtain an adequate overjet lower first premolars were extracted and maximum retraction using mini screws (for maximum anchorage) was applied. Afterwards Rahhal functional appliance was used by the patient 16 hours a day for 6 months and 10 hours a day for another 6 months for retention. After that fixed orthodontic treatment was completed. Lateral cephalometrics were taken, traced and analyzed. In the result Skeletal CLI was obtained (ANB 4 degree), straight facial profile, normal over bite overjet and particular chin development were noticed. As a conclusion, in skeletal CLII malocclusions, lower incisor protrusion will cause a contraindication for functional treatment. Extraction of the lower premolars and retraction of the lower incisors followed by functional orthopedic treatment is an efficient method to treat these cases instead of waiting for orthognathic surgery, also reducing the muscle pressure on the chin will change the development characteristics of it.展开更多
Background: Water weight-loss walking training is an emerging physical therapy technique, which provides new ideas for improving the motor function of stroke patients and improving the quality of life of patients. How...Background: Water weight-loss walking training is an emerging physical therapy technique, which provides new ideas for improving the motor function of stroke patients and improving the quality of life of patients. However, the rehabilitation effect of water weight-loss training in stroke patients is currently unclear. Objective: To analyze the effect of water weight loss walking training in stroke patients. Methods: A total of 180 stroke patients admitted to our hospital from January 2019 to December 2021 were selected and randomly divided into two groups. The control group received routine walking training, and the research group performed weight loss walking training in water on this basis. The lower limb motor function, muscle tone grade, daily living ability, gait and balance ability were compared between the two groups before and after treatment. Results: Compared with the control group, the FMA-LE score (Fugl-Meyer motor assessment of Lower Extremity), MBI score (Modified Barthel Index) and BBS score (berg balance scale) of the study group were higher after treatment, and the muscle tone was lower (P Conclusion: Water weight loss walking training can enhance patients’ muscle tension, correct patients’ abnormal gait, improve patients’ balance and walking ability, and contribute to patients’ motor function recovery and self-care ability improvement.展开更多
The primary goal of this work is to characterize the impact of weighting selection strategy and multistatic geometry on the multistatic radar performance. With the relationship between the multistatic ambiguity functi...The primary goal of this work is to characterize the impact of weighting selection strategy and multistatic geometry on the multistatic radar performance. With the relationship between the multistatic ambiguity function （AF） and the multistatie Cram6r-Rao lower bound （CRLB）, the problem of calculating the multistatic AF and the multistatic CRLB as a performance metric for multistatic radar system is studied. Exactly, based on the proper selection of the system parameters, the multistatic radar performance can be significantly improved. The simulation results illustrate that the multistatic AF and the multistatic CRLB can serve as guidelines for future multistatic fusion rule development and multistatic radars deployment.展开更多
In this paper,the kernel of the cubic spline interpolation is given.An optimal error bound for the cu- bic spline interpolation of lower smooth functions is obtained.
[Objectives]To observe the effect of motor relearning combined with transcranial direct current stimulation on the motor function of lower extremities in patients with cerebral infarction,and to observe its effect on ...[Objectives]To observe the effect of motor relearning combined with transcranial direct current stimulation on the motor function of lower extremities in patients with cerebral infarction,and to observe its effect on gait by 3D gait analysis.[Methods]60 patients with cerebral infarction who met the inclusion criteria were randomly divided into 3 groups according to the order of treatment(n=20).Group A received motor relearning treatment,group B received transcranial direct current stimulation treatment,group C received motor relearning combined with transcranial direct current stimulation,and the curative effect was observed after 5 courses of treatment.[Results]Before treatment,FMA,MBI,spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,stride length,gait speed,stride length deviation,double support)and lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,maximum knee extension,stance phase,swing phase)were compared among the three groups.After treatment,the FMA and MBI of the three groups increased,and the spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,gait speed,double support)and the lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,swing phase)were all improved,while the spatio-temporal parameters(stride length and stride length deviation)and the lower limb joint motion parameters(maximum knee extension and stance phase)decreased.Compared with those before treatment,there were significant differences among the three groups(P<0.05).Through the comparison between groups,it was found that the FMA,MBI,spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,gait speed,double support)and lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,swing phase)in group C were significantly higher than those in group A and B,while the spatio-temporal parameters(stride length and stride length deviation)and lower limb joint motion parameters(maximum knee extension and stance phase)in group C were significantly lower than those in group A and group B,and the difference was statistically significant(P<0.05).[Conclusions]Motor relearning combined with transcranial direct current stimulation could increase MBI and FMA,improve gait spatio-temporal parameters and lower limb joint motion parameters,and correct abnormal gait in patients with cerebral infarction.展开更多
In this paper,the authors employ the splitting method to address support vector machine within a reproducing kernel Banach space framework,where a lower semi-continuous loss function is utilized.They translate support...In this paper,the authors employ the splitting method to address support vector machine within a reproducing kernel Banach space framework,where a lower semi-continuous loss function is utilized.They translate support vector machine in reproducing kernel Banach space with such a loss function to a finite-dimensional tensor optimization problem and propose a splitting method based on the alternating direction method of mul-tipliers.Leveraging Kurdyka-Lojasiewicz property of the augmented Lagrangian function,the authors demonstrate that the sequence derived from this splitting method is globally convergent to a stationary point if the loss function is lower semi-continuous and subana-lytic.Through several numerical examples,they illustrate the effectiveness of the proposed splitting algorithm.展开更多
This study aimed to comprehensively investigate the essential considerations in designing adaptive clothing for women with lower limb prostheses in Saudi Arabia. Employing a qualitative methodology, the research entai...This study aimed to comprehensively investigate the essential considerations in designing adaptive clothing for women with lower limb prostheses in Saudi Arabia. Employing a qualitative methodology, the research entailed semi-structured, in-depth interviews with women utilizing lower limb prostheses and prosthetic specialists. This approach was selected to unearth pivotal design prerequisites and comprehend the specific challenges these women encounter within the realm of clothing. The utilization of selective sampling facilitated the collection of intricate and valuable insights. A Functional, Expressive, and Aesthetic (FEA) User Needs model was utilized to scrutinize participant feedback. Functional requisites encompass ease of dressing and undressing, accessibility to the prosthetic limb, comfort, mobility with the prosthesis, and appropriate fit. Additionally, participants highlighted various expressive needs, including privacy preservation, modesty, camouflaging disability appearances, maintaining alignment with non-disabled women’s fashion, and considerations about the aesthetic aspects of garments.展开更多
Objective: to analyze the clinical value of biofeedback training in elderly stroke patients to promote the recovery of their lower extremity motor dysfunction. Methods: from January 2021 to January 2022, 76 cases of s...Objective: to analyze the clinical value of biofeedback training in elderly stroke patients to promote the recovery of their lower extremity motor dysfunction. Methods: from January 2021 to January 2022, 76 cases of senile stroke were diagnosed in our hospital. They were divided into two groups: control group and observation group. There were 38 cases in each group. The control group was treated with conventional drugs and rehabilitation training. The observation group further increased biofeedback training Lower limb motor dysfunction and daily living ability were evaluated and compared. Results: the difference of Fugl-Meyer scale score between the two groups before treatment was small (P>0.05), and the score of Fugl-Meyer scale in the observation group was higher than that in the control group after treatment (P<0.05);The difference of Barthel index between the two groups before treatment was small (P>0.05), and the Barthel index in the observation group was higher than that in the control group after treatment (P<0.05);The difference of NIHSS scores between the two groups before treatment was small (P>0.05), and the NIHSS scores in the observation group were lower than those in the control group after treatment (P<0.05). Conclusion: the combined use of biofeedback training for elderly stroke patients can effectively promote the rehabilitation of patients, improve their neurological function, enhance the motor function of lower limbs and the ability of self-care in life.展开更多
Objective: to use early rehabilitation treatment for the patients with acute stroke hemiplegia, to observe and analyze its impact on the upper and lower limb function recovery and daily life ability. Methods: in June ...Objective: to use early rehabilitation treatment for the patients with acute stroke hemiplegia, to observe and analyze its impact on the upper and lower limb function recovery and daily life ability. Methods: in June 2021-June 2022 for intercept research time interval, a total of 60 cases of acute stroke hemiplegia, random principle specification grouping, control group received 30 cases of routine treatment, observation group received 30 cases of early rehabilitation treatment, around the upper and lower limb function assessment score, daily life ability evaluation score, balance function, cognitive function scale evaluation score and complication rate data line to compare. Results: before the treatment work, the evaluation results, daily life ability, balance function, and cognitive function evaluation results showed no difference (P> 0.05), and the results were higher (P <0.05);for the complication rate, the observation group showed lower results (P <0.05). Conclusion: for acute stroke cases, early rehabilitation treatment, which can improve the function of upper and lower limbs, strengthen their living ability, balance function and cognitive function, and prevent complications in patients, which is worthy of clinical application.展开更多
文摘In this paper, we characterize lower semi-continuous pseudo-convex functions f : X → R ∪ {+ ∞} on convex subset of real Banach spaces K ⊂ X with respect to the pseudo-monotonicity of its Clarke-Rockafellar Sub-differential. We extend the results on the characterizations of non-smooth convex functions f : X → R ∪ {+ ∞} on convex subset of real Banach spaces K ⊂ X with respect to the monotonicity of its sub-differentials to the lower semi-continuous pseudo-convex functions on real Banach spaces.
文摘Objective:To evaluate the effect of task-oriented training combined with a lower limb rehabilitation robot on improving motor function and ankle joint function in stroke patients with hemiplegia.Methods:Sixty-three stroke patients with hemiplegia admitted to our hospital from January 2022 to June 2024 were randomly divided into observation group(32 cases)and control group(31 cases)using the envelope method.The control group received task-oriented training,while the observation group received additional lower limb rehabilitation robot training.The motor function(Fugl-Meyer Assessment of Lower Extremity,FMA-LE)and ankle joint function(Active Dorsiflexion Range of Motion,DF AROM)were compared between the two groups.Results:After treatment,the levels of FMA-LE and DF AROM in both groups increased significantly,and the improvement in each index in the observation group was better than that in the control group(P<0.05).Conclusion:The combination of task-oriented training and lower limb rehabilitation robot training can more effectively improve the overall motor function of the lower limbs and the active dorsiflexion ability of the ankle joint in stroke patients with hemiplegia.
文摘The purpose of this paper is to make a further study on the abstract economy. Here, for the constraint correspondences we assume that they are almost lower semi-continuous (n-lower semi-continuous), which is weaken than that they are lower semi-continuous. Several equilibria existence theorems are proved.
基金supported by the 1·3·5 project for disciplines of excellence-Clinical Research Incubation Project,West China Hospital,Sichuan University,China,No.2020HXFH051(to QG).
文摘Transcranial magnetic stimulation,a type of noninvasive brain stimulation,has become an ancillary therapy for motor function rehabilitation.Most previous studies have focused on the effects of repetitive transcranial magnetic stimulation(rTMS)on motor function in stroke patients.There have been relatively few studies on the effects of different modalities of rTMS on lower extremity motor function and corticospinal excitability in patients with stroke.The MEDLINE,Embase,Cochrane Library,ISI Science Citation Index,Physiotherapy Evidence Database,China National Knowledge Infrastructure Library,and ClinicalTrials.gov databases were searched.Parallel or crossover randomized controlled trials that addressed the effectiveness of rTMS in patients with stroke,published from inception to November 28,2019,were included.Standard pairwise meta-analysis was conducted using R version 3.6.1 with the“meta”package.Bayesian network analysis using the Markov chain Monte Carlo algorithm was conducted to investigate the effectiveness of different rTMS protocol interventions.Network meta-analysis results of 18 randomized controlled trials regarding lower extremity motor function recovery revealed that low-frequency rTMS had better efficacy in promoting lower extremity motor function recovery than sham stimulation.Network meta-analysis results of five randomized controlled trials demonstrated that highfrequency rTMS led to higher amplitudes of motor evoked potentials than low-frequency rTMS or sham stimulation.These findings suggest that rTMS can improve motor function in patients with stroke,and that low-frequency rTMS mainly affects motor function,whereas high-frequency rTMS increases the amplitudes of motor evoked potentials.More highquality randomized controlled trials are needed to validate this conclusion.The work was registered in PROSPERO(registration No.CRD42020147055)on April 28,2020.
基金Project supported by the Academic Human Resources Development in Institutions of Higher Learning under the Jurisdiction of Beijing Municipality (IHLB201008257)Scientific Research Common Program of Beijing Municipal Commission of Education (KM200810011005)+1 种基金PHR (IHLB 201102)research grant of University of Macao MYRG142(Y1-L2)-FST111-KKI
文摘The main objective is to derive a lower bound from an upper one for harmonic functions in the half space, which extends a result of B. Y. Levin from dimension 2 to dimension n 〉 2. To this end, we first generalize the Carleman＇s formula for harmonic functions in the half plane to higher dimensional half space, and then establish a Nevanlinna＇s representation for harmonic functions in the half sphere by using HSrmander＇s theorem.
文摘This study investigated the correlation between periprostatic fat thickness(PPFT)measured on magnetic resonance imaging and lower urinary tract symptoms,erectile function,and benign prostatic hyperplasia(BPH)progression.A total of 286 treatment-naive men diagnosed with BPH in our department between March 2017 and February 2019 were included.Patients were divided into two groups according to the median value of PPFT:high(PPFT>4.35 mm)PPFT group and low(PPFT<4.35 mm)PPFT group.After the initial evaluation,all patients received a combination drug treatment of tamsulosin and finasteride for 12 months.Of the 286 enrolled patients,244 completed the drug treatment course.Patients with high PPFT had larger prostate volume(PV;P=0.013),higher International Prostate Symptom Score(IPSS;P-0.008),and lower five-item version of the International Index of Erectile Function(IIEF-5)score(P=0.002)than those with low PPFT.Both high and low PPFT groups showed significant improvements in PV,maximum flow rate,IPSS,and quality of life score and a decrease of IIEF-5 score after the combination drug treatment.The decrease of IIEF-5 score was more obvious in the high PPFT group than that in the low PPFT group.In addition,more patients in the high PPFT group underwent prostate surgery than those in the low PPFT group.Moreover,Pearson’s correlation coefficient analysis indicated that PPFT was positively correlated with age,PV,and IPSS and negatively correlated with IIEF-5 score;however,body mass index was only negatively correlated with IIEF-5 score.
文摘The relationship between acute high altitude response (AHAR), cardiac function injury, and high altitude de-adaptation response (HADAR) was assessed. Cardiac function indicators were assessed for 96 men (18 - 35 years old) deployed into a high altitude (3700 - 4800 m) environment requiring intense physical activity. The subjects were divided into 3 groups based on AHAR at high altitude: severe AHAR (n = 24), mild to moderate AHAR (Group B, n = 47) and non-AHAR (Group C, 25);and based on HADAR: severe HADAR (Group E, n = 19), mild to moderate HADAR (Group F, n = 40) and non-HADAR (Group G, n = 37) after return to lower altitude (1,500 m). Cardiac function indicators were measured after 50 days at high altitude and at 12 h, 15 days, and 30 days after return to lower altitude. Controls were 50 healthy volunteers (Group D, n = 50) at 1500 m. Significant differences were observed in cardiac function indicators among groups A, B, C, and D. AHAR score was positively correlated with HADAR score (r = 0.863, P < 0.001). Significant differ- ences were also observed in cardiac function indicators among groups D, E, F, and G, 12 h and15 days after return to lower altitude. There were no significant differences in cardiac function indicators among the groups, 30 days after return to lower altitude, compared to group D. The results indicated that the severity of HADAR is associated with the severity of AHAR and cardiac injury, and prolonged recovery.
基金This work has received funding from the European Union Horizon 2020 research and innovation programmer under the Marie Sklodowska-Curie grant agreement No.701697,Major Program of the National Social Science Fund of China(Grant No.17ZDA092)Basic Research Programs(Natural Science Foundation)of Jiangsu Province(BK20180794)+1 种基金333 High-Level Talent Cultivation Project of Jiangsu Province(BRA2018332)the PAPD fund.
文摘Functional electrical stimulation is a method of repairing a dysfunctional limb in a stroke patient by using low-intensity electrical stimulation.Currently,it is widely used in smart medical treatment for limb rehabilitation in stroke patients.In this paper,the development of FES systems is sorted out and analyzed in a time order.Then,the progress of functional electrical stimulation in the field of rehabilitation is reviewed in details in two aspects,i.e.,system development and algorithm progress.In the system aspect,the development of the first FES control and stimulation system,the core of the lower limb-based neuroprosthesis system and the system based on brain-computer interface are introduced.The algorithm optimization for control strategy is introduced in the algorithm.Asynchronous stimulation to prolong the function time of the lower limbs and a method to improve the robustness of knee joint modeling using neural networks.Representative applications in each of these aspects have been investigated and analyzed.
基金supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT)(No. 2021R1I1A1A0105621313, No. 2022R1F1A1074441, No. 2022K1A3A1A20014496, and No. 2022R1F1A1074083)supported by the Ministry of Education Funding (No. RIS 2021-004)supported by the Brain Pool program funded by the Ministry of Science and ICT through the National Research Foundation of Korea (RS-2023-00284318).
文摘In this study,precise control over the thickness and termination of Ti3C2TX MXene flakes is achieved to enhance their electrical properties,environmental stability,and gas-sensing performance.Utilizing a hybrid method involving high-pressure processing,stirring,and immiscible solutions,sub-100 nm MXene flake thickness is achieved within the MXene film on the Si-wafer.Functionalization control is achieved by defunctionalizing MXene at 650℃ under vacuum and H2 gas in a CVD furnace,followed by refunctionalization with iodine and bromine vaporization from a bubbler attached to the CVD.Notably,the introduction of iodine,which has a larger atomic size,lower electronegativity,reduce shielding effect,and lower hydrophilicity(contact angle:99°),profoundly affecting MXene.It improves the surface area(36.2 cm^(2) g^(-1)),oxidation stability in aqueous/ambient environments(21 days/80 days),and film conductivity(749 S m^(-1)).Additionally,it significantly enhances the gas-sensing performance,including the sensitivity(0.1119Ωppm^(-1)),response(0.2% and 23%to 50 ppb and 200 ppm NO_(2)),and response/recovery times(90/100 s).The reduced shielding effect of the–I-terminals and the metallic characteristics of MXene enhance the selectivity of I-MXene toward NO2.This approach paves the way for the development of stable and high-performance gas-sensing two-dimensional materials with promising prospects for future studies.
文摘In this paper lower semicontinuity of the functional I(u)=∫_Ωf(x,u,Δ~ _Hu)dx is investigated for f being a Carathéodory function defined on Hn×R×R^2n and for u∈SBV_H(Ω),where Hn is the Heisenberg group with dimension 2n+1,ΩHn is an open set and Δ~ _Hu denotes the approximate derivative of the absolute continuous part Da_Hu with respect to D_Hu.In addition,a Lusin type approximation theorem for a SBV_H function is proved.
文摘Treatment of skeletal Cl II includes functional orthopedic treatment, head-gears, extraction of the upper premolars and orthognathic surgery. To treat any patient with functional appliances (bite jumping) an adequate overjet is necessary. In this case an 11 years old female patient has skeletal CLII due to mandibular deficiency with ANB angle 8 degrees, overbite: 3 mm, overjet: 1 mm, extremely convex profile and underdeveloped chin due to the hyper muscle contraction of the lower lip to obtain oral seal. To obtain an adequate overjet lower first premolars were extracted and maximum retraction using mini screws (for maximum anchorage) was applied. Afterwards Rahhal functional appliance was used by the patient 16 hours a day for 6 months and 10 hours a day for another 6 months for retention. After that fixed orthodontic treatment was completed. Lateral cephalometrics were taken, traced and analyzed. In the result Skeletal CLI was obtained (ANB 4 degree), straight facial profile, normal over bite overjet and particular chin development were noticed. As a conclusion, in skeletal CLII malocclusions, lower incisor protrusion will cause a contraindication for functional treatment. Extraction of the lower premolars and retraction of the lower incisors followed by functional orthopedic treatment is an efficient method to treat these cases instead of waiting for orthognathic surgery, also reducing the muscle pressure on the chin will change the development characteristics of it.
文摘Background: Water weight-loss walking training is an emerging physical therapy technique, which provides new ideas for improving the motor function of stroke patients and improving the quality of life of patients. However, the rehabilitation effect of water weight-loss training in stroke patients is currently unclear. Objective: To analyze the effect of water weight loss walking training in stroke patients. Methods: A total of 180 stroke patients admitted to our hospital from January 2019 to December 2021 were selected and randomly divided into two groups. The control group received routine walking training, and the research group performed weight loss walking training in water on this basis. The lower limb motor function, muscle tone grade, daily living ability, gait and balance ability were compared between the two groups before and after treatment. Results: Compared with the control group, the FMA-LE score (Fugl-Meyer motor assessment of Lower Extremity), MBI score (Modified Barthel Index) and BBS score (berg balance scale) of the study group were higher after treatment, and the muscle tone was lower (P Conclusion: Water weight loss walking training can enhance patients’ muscle tension, correct patients’ abnormal gait, improve patients’ balance and walking ability, and contribute to patients’ motor function recovery and self-care ability improvement.
基金Project(61271441)supported by the National Natural Science Foundation of ChinaProject(NCET-10-0895)supported by the Program for New Century Excellent Talents in Universities of China
文摘The primary goal of this work is to characterize the impact of weighting selection strategy and multistatic geometry on the multistatic radar performance. With the relationship between the multistatic ambiguity function （AF） and the multistatie Cram6r-Rao lower bound （CRLB）, the problem of calculating the multistatic AF and the multistatic CRLB as a performance metric for multistatic radar system is studied. Exactly, based on the proper selection of the system parameters, the multistatic radar performance can be significantly improved. The simulation results illustrate that the multistatic AF and the multistatic CRLB can serve as guidelines for future multistatic fusion rule development and multistatic radars deployment.
文摘In this paper,the kernel of the cubic spline interpolation is given.An optimal error bound for the cu- bic spline interpolation of lower smooth functions is obtained.
基金Supported by Scientific Research Project of Chinese Medicine of Hubei Provincial Health Commission(ZY2021Q015)Project of Taihe Hospital(2021JJXM077,2019JJXM099,2016JJXM023)。
文摘[Objectives]To observe the effect of motor relearning combined with transcranial direct current stimulation on the motor function of lower extremities in patients with cerebral infarction,and to observe its effect on gait by 3D gait analysis.[Methods]60 patients with cerebral infarction who met the inclusion criteria were randomly divided into 3 groups according to the order of treatment(n=20).Group A received motor relearning treatment,group B received transcranial direct current stimulation treatment,group C received motor relearning combined with transcranial direct current stimulation,and the curative effect was observed after 5 courses of treatment.[Results]Before treatment,FMA,MBI,spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,stride length,gait speed,stride length deviation,double support)and lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,maximum knee extension,stance phase,swing phase)were compared among the three groups.After treatment,the FMA and MBI of the three groups increased,and the spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,gait speed,double support)and the lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,swing phase)were all improved,while the spatio-temporal parameters(stride length and stride length deviation)and the lower limb joint motion parameters(maximum knee extension and stance phase)decreased.Compared with those before treatment,there were significant differences among the three groups(P<0.05).Through the comparison between groups,it was found that the FMA,MBI,spatio-temporal parameters for 3D gait analysis(gait frequency,gait cycle,gait speed,double support)and lower limb joint motion parameters(affected side stride length,maximum hip flexion,maximum hip extension,maximum knee flexion,swing phase)in group C were significantly higher than those in group A and B,while the spatio-temporal parameters(stride length and stride length deviation)and lower limb joint motion parameters(maximum knee extension and stance phase)in group C were significantly lower than those in group A and group B,and the difference was statistically significant(P<0.05).[Conclusions]Motor relearning combined with transcranial direct current stimulation could increase MBI and FMA,improve gait spatio-temporal parameters and lower limb joint motion parameters,and correct abnormal gait in patients with cerebral infarction.
基金supported by the National Natural Science Foundation of China(Nos.12026602,12071157,12271108)the Natural Science Foundation of Guangdong Provience(No.2024A1515012288)+1 种基金the Science and Technology Commission of Shanghai Municipality(No.23JC1400501)the Ministry of Science and Technology of China(No.G2023132005L).
文摘In this paper,the authors employ the splitting method to address support vector machine within a reproducing kernel Banach space framework,where a lower semi-continuous loss function is utilized.They translate support vector machine in reproducing kernel Banach space with such a loss function to a finite-dimensional tensor optimization problem and propose a splitting method based on the alternating direction method of mul-tipliers.Leveraging Kurdyka-Lojasiewicz property of the augmented Lagrangian function,the authors demonstrate that the sequence derived from this splitting method is globally convergent to a stationary point if the loss function is lower semi-continuous and subana-lytic.Through several numerical examples,they illustrate the effectiveness of the proposed splitting algorithm.
文摘This study aimed to comprehensively investigate the essential considerations in designing adaptive clothing for women with lower limb prostheses in Saudi Arabia. Employing a qualitative methodology, the research entailed semi-structured, in-depth interviews with women utilizing lower limb prostheses and prosthetic specialists. This approach was selected to unearth pivotal design prerequisites and comprehend the specific challenges these women encounter within the realm of clothing. The utilization of selective sampling facilitated the collection of intricate and valuable insights. A Functional, Expressive, and Aesthetic (FEA) User Needs model was utilized to scrutinize participant feedback. Functional requisites encompass ease of dressing and undressing, accessibility to the prosthetic limb, comfort, mobility with the prosthesis, and appropriate fit. Additionally, participants highlighted various expressive needs, including privacy preservation, modesty, camouflaging disability appearances, maintaining alignment with non-disabled women’s fashion, and considerations about the aesthetic aspects of garments.
文摘Objective: to analyze the clinical value of biofeedback training in elderly stroke patients to promote the recovery of their lower extremity motor dysfunction. Methods: from January 2021 to January 2022, 76 cases of senile stroke were diagnosed in our hospital. They were divided into two groups: control group and observation group. There were 38 cases in each group. The control group was treated with conventional drugs and rehabilitation training. The observation group further increased biofeedback training Lower limb motor dysfunction and daily living ability were evaluated and compared. Results: the difference of Fugl-Meyer scale score between the two groups before treatment was small (P>0.05), and the score of Fugl-Meyer scale in the observation group was higher than that in the control group after treatment (P<0.05);The difference of Barthel index between the two groups before treatment was small (P>0.05), and the Barthel index in the observation group was higher than that in the control group after treatment (P<0.05);The difference of NIHSS scores between the two groups before treatment was small (P>0.05), and the NIHSS scores in the observation group were lower than those in the control group after treatment (P<0.05). Conclusion: the combined use of biofeedback training for elderly stroke patients can effectively promote the rehabilitation of patients, improve their neurological function, enhance the motor function of lower limbs and the ability of self-care in life.
文摘Objective: to use early rehabilitation treatment for the patients with acute stroke hemiplegia, to observe and analyze its impact on the upper and lower limb function recovery and daily life ability. Methods: in June 2021-June 2022 for intercept research time interval, a total of 60 cases of acute stroke hemiplegia, random principle specification grouping, control group received 30 cases of routine treatment, observation group received 30 cases of early rehabilitation treatment, around the upper and lower limb function assessment score, daily life ability evaluation score, balance function, cognitive function scale evaluation score and complication rate data line to compare. Results: before the treatment work, the evaluation results, daily life ability, balance function, and cognitive function evaluation results showed no difference (P> 0.05), and the results were higher (P <0.05);for the complication rate, the observation group showed lower results (P <0.05). Conclusion: for acute stroke cases, early rehabilitation treatment, which can improve the function of upper and lower limbs, strengthen their living ability, balance function and cognitive function, and prevent complications in patients, which is worthy of clinical application.
