Previous studies have revealed the miR164 family and the miR164-targeted NAC transcription factor genes in rice(Oryza sativa)and Arabidopsis that play versatile roles in developmental processes and stress responses.In...Previous studies have revealed the miR164 family and the miR164-targeted NAC transcription factor genes in rice(Oryza sativa)and Arabidopsis that play versatile roles in developmental processes and stress responses.In wheat(Triticum aestivum L.),we found nine genetic loci of tae-miR164(tae-MIR164 a to i)producing two mature sequences that downregulate the expression of three newly identified target genes of TaNACs(TaNAC1,TaNAC11,and TaNAC14)by the cleavage of the respective mRNAs.Overexpression of tae-miR164 or one of its target genes(TaNAC14)demonstrated that the miR164-TaNAC14 module greatly affects root growth and development and stress(drought and salinity)tolerance in wheat seedlings,and TaNAC14 promotes root growth and development in wheat seedlings and enhances drought tolerance,while tae-miR164 inhibits root development and reduces drought and salinity tolerance by downregulating the expression of TaNAC14.These findings identify the miR164-TaNAC14 module as well as other taemiR164-regulated genes which can serve as new genetic resources for stress-resistance wheat breeding.展开更多
DBC substrates are the standard circuit boardsfor power modules. Using the DBC technologythick copper foils (0.125mm - 0.Tmm) arecladded to Alumina or Aluminum Nitride,The strong adhesion of the copper to ceramicbond ...DBC substrates are the standard circuit boardsfor power modules. Using the DBC technologythick copper foils (0.125mm - 0.Tmm) arecladded to Alumina or Aluminum Nitride,The strong adhesion of the copper to ceramicbond reduces the thermal expansion coefficientin horizontal direction only slightly above theTEC of the ceramic itself. This allows directsilicon attach of large dies without using TECcontrolling layers.As DBC technology is using copper foils,integralleads overhanging the ceramic can be realized...展开更多
There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical archit...There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical architecture is selected to design and develop the POB plan management module applicable to offshore platform facilities. The main functions of this module include task management, facility management, area management, sea-going unit management, plan management, report management, authority control, and comprehensive query. It can efficiently solve on-site business problems and improve the efficiency of POB plan management for various professionals on land and at sea. In actual use, the module can well assist in completing POB plan management tasks and improve work efficiency.展开更多
Sulfadiazine(SD)is a common antibiotic administered to treat bacterial infections in livestock,and its fate andmigration are greatly affected by dissolved organicmatter(DOM).The soil infiltration system[a typical low-...Sulfadiazine(SD)is a common antibiotic administered to treat bacterial infections in livestock,and its fate andmigration are greatly affected by dissolved organicmatter(DOM).The soil infiltration system[a typical low-impact development(LID)facility]can significantly alterDOMproperties during runoff pollution,thus affecting the complexation of SDwithDOM.Here,the binding characteristics of different DOM components and SD in the soil infiltration system were explored using spectroscopic techniques(excitation–emission matrices,parallel factor analysis,and synchronous fluorescence spectroscopy).Combined with the weakening of DOM fluorescence intensity and 78.63%reduction in mean SD concentration following treatment,synchronous degradation may have occurred.The binding sequence of SD and DOM fluorophores was further explored using two-dimensional correlation spectroscopy.Effluent DOM showed greater sensitivity to SD and more binding sites than influent DOM.Moreover,hydrophobic protein-like substances exhibited higher log K_(M) values than other fluorescent components,indicating that protein-like components play significant roles in SD complexation.The soil percolation system improved the complexation stability and binding sequence of fulvic-like substances.Thus,SD–DOM can be intercepted and degraded using LID facilities to reduce the risk of SD in aquatic environments.展开更多
Low-impact development (LID) technologies have a great potential to reduce water usage and stormwa- ter runoff and are therefore seen as sustainable improvements that can be made to traditional water infrastructure,...Low-impact development (LID) technologies have a great potential to reduce water usage and stormwa- ter runoff and are therefore seen as sustainable improvements that can be made to traditional water infrastructure, These technologies include bioretention areas, rainwater capturing, and xeriscaping, all of which can be used in residential zones, Within the City of Atlanta, residential water usage accounts for 53% of the total water consumption; therefore, residential zones offer significant impact potential for the implementation of LID, This study analyzes the use of LID strategies within the different residen- tial zones of the City of Atlanta from an ecological perspective by drawing analogies to natural ecosys- tems, The analysis shows that these technologies, especially with the addition of a graywater system, work to improve the conventional residential water network based upon these ecological metrics, The higher metric values suggest greater parity with healthy, natural ecosystems.展开更多
Modules enable students to engage with content at their own pace,fostering autonomy and deeper understanding.The modular approach ensures clarity in presenting objectives,instructions,and concepts,while having illustr...Modules enable students to engage with content at their own pace,fostering autonomy and deeper understanding.The modular approach ensures clarity in presenting objectives,instructions,and concepts,while having illustrations,activities,and assessments could enhance comprehension and retention.This paper was a developmental study on STS module for college students using the ADDIE Model(Analysis,Design,Development,Implementation,and Evaluation).Sampled 673 first-year students from Northwest Samar State University participated in the study,with 299 participating in a test try-out and 374 in the students’performance evaluation.Three expert evaluators with backgrounds in science,English,and psychology,each with over four years of experience,assessed the modules to ensure alignment with the study’s constructivist learning goals and instructional integrity.The findings revealed that both students and experts had rated the instructional module positively,indicating its effectiveness in facilitating learning and completing lessons.Key aspects such as the style of illustrations and written expressions,the usefulness of learning activities,and the guidance provided by illustrations and captions were especially well-received.The module was praised for its clear objectives,understandable instructions,and engaging tasks like trivia and puzzles.Expert evaluations highlighted relevance,simplicity,and balanced emphasis on topics in the module content.Furthermore,students in test group demonstrated significant improvement in performance,with post-test scores notably higher than pre-test scores,confirming the module’s effectiveness in enhancing learning outcomes.Consequently,this paper provides an opportunity to integrate science learning with initiatives aimed at promoting environmental preservation and driving social change.展开更多
Interpretation of primary growth markers (modules) is neglected in sustainable resource management processes, yet it opens up prospects for long time series on tree crown development, necessary for their characterizat...Interpretation of primary growth markers (modules) is neglected in sustainable resource management processes, yet it opens up prospects for long time series on tree crown development, necessary for their characterization in the current context of climate change. This study aimed to assess the morphological variation of crown shoots in <i><span style="font-family:Verdana;">Parkia biglobosa</span></i><span style="font-family:Verdana;"> in the face of a changing environment. Axis growth modules of 420 individuals of different ages were retrospectively analyzed in the presence or absence of shading during the wet and dry seasons in seven localities in Cote d’Ivoire. The results showed that the developmental environment of individuals did not influence the growth modules dimensions (P > 0.05). However, module size remained significantly different between locations (P < 0.05). The southern part of the gradient is still favourable and has priority for the establishment of permanent plots. The modules morphology differs from the youngest to the oldest individuals (P < 0.05). The rainy season remains the ideal period for the implementation of agroforestry reforestation programmes based on this species (P < 0.05). </span><i><span style="font-family:Verdana;">Parkia biglobosa</span></i><span style="font-family:Verdana;"> is a monochasial sympod (Pseudo-monopod) with a relay axis that follows the Paul Champagnat architectural model in the young stage, and transits to the Wilhelm Troll model later in the adult and old stage. This information contributes to the understanding of the functioning of crown and the adaptation of this species to a varying environment. It could guide choice of suitable environment and ideal genotype for the implementation of a reforestation or agroforestry programme based on </span><i><span style="font-family:Verdana;">Parkia biglobosa</span></i><span style="font-family:Verdana;">.</span>展开更多
Haptoglobin,a protein primarily recognized for its role in sequestering free hemoglobin,has been identified as a molecule with diverse and underexplored functions in the pathophysiology of various diseases.This editor...Haptoglobin,a protein primarily recognized for its role in sequestering free hemoglobin,has been identified as a molecule with diverse and underexplored functions in the pathophysiology of various diseases.This editorial explores the multifaceted roles of haptoglobin,highlighting its involvement in inflammatory responses and immune regulation and its potential implications in chronic diseases such as diabetes,cardiovascular disorders,and cancer.Through a synthesis of recent research findings,this editorial reveals the importance of haptoglobin in disease mechanisms and underscores the need for further investigation to fully elucidate its therapeutic potential.A comprehensive understanding of haptoglobin’s novel functions may catalyze the development of innovative diagnostic and therapeutic modalities in clinical practice.展开更多
Linux-based Platform for Open Architecture Controller ( POAC ), a new open architecture controller and its modular developing method are discussed. POAC divides the application software of controller into the developi...Linux-based Platform for Open Architecture Controller ( POAC ), a new open architecture controller and its modular developing method are discussed. POAC divides the application software of controller into the developing system and the application system. In the developing system, PAOC abstracts a series of function modules with unified data interface and function interface. In the application system, POAC defines the model of the architecture module, realizing the interoperability and interchangeability between the architecture modules. The modular developing method entities the users to make up an application system with some architecture modules, which consist of a set of function modules. The modular developing method decreases the developing time from the standard of controller architecture to the product.展开更多
The dismantling and recycling of junction boxes,which is an important part of the photovoltaic module recycling process,was tested and designed scientifically.The equipment framework was built by three-dimensional sim...The dismantling and recycling of junction boxes,which is an important part of the photovoltaic module recycling process,was tested and designed scientifically.The equipment framework was built by three-dimensional simulation,and then the design of dismantling and recycling equipment for junction boxes of waste crystal silicon photovoltaic modules was completed through the experimental test and data analysis.The experimental results show that the initial idea of the dismantling scheme is correct,and the structure is feasible.However,some problems were not considered.This study provides reliable data support for the subsequent equipment development and ensures the smooth development of the subsequent design work.展开更多
Enhancing crop productivity and quality remains a paramount breeding objective to address the dual challenges of global population growth and escalating demand.Cereal endosperms,particularly in staple crops such as ri...Enhancing crop productivity and quality remains a paramount breeding objective to address the dual challenges of global population growth and escalating demand.Cereal endosperms,particularly in staple crops such as rice,wheat,and maize,constitute the world's primary source of human nutrition and animal feed.展开更多
Putrescine plays a role in superficial scald development during the cold storage of pear fruit.However,the molecular mechanism behind this phenomenon has not been un-fully clarified until recently.In this study,a conj...Putrescine plays a role in superficial scald development during the cold storage of pear fruit.However,the molecular mechanism behind this phenomenon has not been un-fully clarified until recently.In this study,a conjoint analysis of metabolites and gene expression profiles in the putrescine-metabolic pathway of P.bretschneideri Rehd.fruit followed by experimental validation revealed that PbrADC1,forming a homodimer in the chloroplast,was involved in putrescine biosynthesis and thus fruit chilling resistance.Additionally,the substrate-binding residue Cys^(546)in PbrADC1,whose activity was modified by H_(2)O_(2),played a crucial role in arginine decarboxylation into agmatine.Through a combined analysis of the distribution of cis-acting elements in the PbrADC1 promoter as well as the expression profiles of related transcription factors(TFs),several TFs were identified as upstream regulators of PbrADC1 gene.Further investigation revealed that the nuclear PbrWRKY62 could directly bind to the W-box elements in the PbrADC1 promoter,activate its expression,enhance putrescine accumulation,and thus increase fruit chilling tolerance.In conclusion,our results suggest that the PbrWRKY62-PbrADC1 module is involved in the development of superficial scald in P.bretschneideri Rehd.fruit via regulating putrescine biosynthesis.Consequently,these findings could serve as valuable genetic resources for breeding scald-resistant pear fruit.展开更多
基金financially supported by the National Natural Science Foundation of China(32072003and 32072059)the Key Research and Development Program of Shaanxi Province,China(2021NY-079)。
文摘Previous studies have revealed the miR164 family and the miR164-targeted NAC transcription factor genes in rice(Oryza sativa)and Arabidopsis that play versatile roles in developmental processes and stress responses.In wheat(Triticum aestivum L.),we found nine genetic loci of tae-miR164(tae-MIR164 a to i)producing two mature sequences that downregulate the expression of three newly identified target genes of TaNACs(TaNAC1,TaNAC11,and TaNAC14)by the cleavage of the respective mRNAs.Overexpression of tae-miR164 or one of its target genes(TaNAC14)demonstrated that the miR164-TaNAC14 module greatly affects root growth and development and stress(drought and salinity)tolerance in wheat seedlings,and TaNAC14 promotes root growth and development in wheat seedlings and enhances drought tolerance,while tae-miR164 inhibits root development and reduces drought and salinity tolerance by downregulating the expression of TaNAC14.These findings identify the miR164-TaNAC14 module as well as other taemiR164-regulated genes which can serve as new genetic resources for stress-resistance wheat breeding.
文摘DBC substrates are the standard circuit boardsfor power modules. Using the DBC technologythick copper foils (0.125mm - 0.Tmm) arecladded to Alumina or Aluminum Nitride,The strong adhesion of the copper to ceramicbond reduces the thermal expansion coefficientin horizontal direction only slightly above theTEC of the ceramic itself. This allows directsilicon attach of large dies without using TECcontrolling layers.As DBC technology is using copper foils,integralleads overhanging the ceramic can be realized...
文摘There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical architecture is selected to design and develop the POB plan management module applicable to offshore platform facilities. The main functions of this module include task management, facility management, area management, sea-going unit management, plan management, report management, authority control, and comprehensive query. It can efficiently solve on-site business problems and improve the efficiency of POB plan management for various professionals on land and at sea. In actual use, the module can well assist in completing POB plan management tasks and improve work efficiency.
基金supported by the National Water Pollution Control and Management Technology Major Project(No.2018ZX07110005)the National Natural Science Foundation of China(No.52170097)+1 种基金the Fundamental Research Funds for Beijing University of Civil Engineering and Architecture(No.X20137)BUCEA Post Graduate Innovation Project(No.2022).
文摘Sulfadiazine(SD)is a common antibiotic administered to treat bacterial infections in livestock,and its fate andmigration are greatly affected by dissolved organicmatter(DOM).The soil infiltration system[a typical low-impact development(LID)facility]can significantly alterDOMproperties during runoff pollution,thus affecting the complexation of SDwithDOM.Here,the binding characteristics of different DOM components and SD in the soil infiltration system were explored using spectroscopic techniques(excitation–emission matrices,parallel factor analysis,and synchronous fluorescence spectroscopy).Combined with the weakening of DOM fluorescence intensity and 78.63%reduction in mean SD concentration following treatment,synchronous degradation may have occurred.The binding sequence of SD and DOM fluorophores was further explored using two-dimensional correlation spectroscopy.Effluent DOM showed greater sensitivity to SD and more binding sites than influent DOM.Moreover,hydrophobic protein-like substances exhibited higher log K_(M) values than other fluorescent components,indicating that protein-like components play significant roles in SD complexation.The soil percolation system improved the complexation stability and binding sequence of fulvic-like substances.Thus,SD–DOM can be intercepted and degraded using LID facilities to reduce the risk of SD in aquatic environments.
基金This work was supported by a grant for "Resilient Interdependent Infrastructure Processes and Systems (RIPS) Type 2: Participatory Modeling of Complex Urban Infrastructure Systems (Model Urban SysTems)" (#0836046) from the National Science Foundation, Division of Emerging Frontiers in Research and Innovations (EFRI). Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation. The authors acknowledge the work of Jeong et al. for the use of data and support in this analysis.
文摘Low-impact development (LID) technologies have a great potential to reduce water usage and stormwa- ter runoff and are therefore seen as sustainable improvements that can be made to traditional water infrastructure, These technologies include bioretention areas, rainwater capturing, and xeriscaping, all of which can be used in residential zones, Within the City of Atlanta, residential water usage accounts for 53% of the total water consumption; therefore, residential zones offer significant impact potential for the implementation of LID, This study analyzes the use of LID strategies within the different residen- tial zones of the City of Atlanta from an ecological perspective by drawing analogies to natural ecosys- tems, The analysis shows that these technologies, especially with the addition of a graywater system, work to improve the conventional residential water network based upon these ecological metrics, The higher metric values suggest greater parity with healthy, natural ecosystems.
文摘Modules enable students to engage with content at their own pace,fostering autonomy and deeper understanding.The modular approach ensures clarity in presenting objectives,instructions,and concepts,while having illustrations,activities,and assessments could enhance comprehension and retention.This paper was a developmental study on STS module for college students using the ADDIE Model(Analysis,Design,Development,Implementation,and Evaluation).Sampled 673 first-year students from Northwest Samar State University participated in the study,with 299 participating in a test try-out and 374 in the students’performance evaluation.Three expert evaluators with backgrounds in science,English,and psychology,each with over four years of experience,assessed the modules to ensure alignment with the study’s constructivist learning goals and instructional integrity.The findings revealed that both students and experts had rated the instructional module positively,indicating its effectiveness in facilitating learning and completing lessons.Key aspects such as the style of illustrations and written expressions,the usefulness of learning activities,and the guidance provided by illustrations and captions were especially well-received.The module was praised for its clear objectives,understandable instructions,and engaging tasks like trivia and puzzles.Expert evaluations highlighted relevance,simplicity,and balanced emphasis on topics in the module content.Furthermore,students in test group demonstrated significant improvement in performance,with post-test scores notably higher than pre-test scores,confirming the module’s effectiveness in enhancing learning outcomes.Consequently,this paper provides an opportunity to integrate science learning with initiatives aimed at promoting environmental preservation and driving social change.
文摘Interpretation of primary growth markers (modules) is neglected in sustainable resource management processes, yet it opens up prospects for long time series on tree crown development, necessary for their characterization in the current context of climate change. This study aimed to assess the morphological variation of crown shoots in <i><span style="font-family:Verdana;">Parkia biglobosa</span></i><span style="font-family:Verdana;"> in the face of a changing environment. Axis growth modules of 420 individuals of different ages were retrospectively analyzed in the presence or absence of shading during the wet and dry seasons in seven localities in Cote d’Ivoire. The results showed that the developmental environment of individuals did not influence the growth modules dimensions (P > 0.05). However, module size remained significantly different between locations (P < 0.05). The southern part of the gradient is still favourable and has priority for the establishment of permanent plots. The modules morphology differs from the youngest to the oldest individuals (P < 0.05). The rainy season remains the ideal period for the implementation of agroforestry reforestation programmes based on this species (P < 0.05). </span><i><span style="font-family:Verdana;">Parkia biglobosa</span></i><span style="font-family:Verdana;"> is a monochasial sympod (Pseudo-monopod) with a relay axis that follows the Paul Champagnat architectural model in the young stage, and transits to the Wilhelm Troll model later in the adult and old stage. This information contributes to the understanding of the functioning of crown and the adaptation of this species to a varying environment. It could guide choice of suitable environment and ideal genotype for the implementation of a reforestation or agroforestry programme based on </span><i><span style="font-family:Verdana;">Parkia biglobosa</span></i><span style="font-family:Verdana;">.</span>
文摘Haptoglobin,a protein primarily recognized for its role in sequestering free hemoglobin,has been identified as a molecule with diverse and underexplored functions in the pathophysiology of various diseases.This editorial explores the multifaceted roles of haptoglobin,highlighting its involvement in inflammatory responses and immune regulation and its potential implications in chronic diseases such as diabetes,cardiovascular disorders,and cancer.Through a synthesis of recent research findings,this editorial reveals the importance of haptoglobin in disease mechanisms and underscores the need for further investigation to fully elucidate its therapeutic potential.A comprehensive understanding of haptoglobin’s novel functions may catalyze the development of innovative diagnostic and therapeutic modalities in clinical practice.
基金Shanghai Science and Technology Development Foundation (995107017)
文摘Linux-based Platform for Open Architecture Controller ( POAC ), a new open architecture controller and its modular developing method are discussed. POAC divides the application software of controller into the developing system and the application system. In the developing system, PAOC abstracts a series of function modules with unified data interface and function interface. In the application system, POAC defines the model of the architecture module, realizing the interoperability and interchangeability between the architecture modules. The modular developing method entities the users to make up an application system with some architecture modules, which consist of a set of function modules. The modular developing method decreases the developing time from the standard of controller architecture to the product.
文摘The dismantling and recycling of junction boxes,which is an important part of the photovoltaic module recycling process,was tested and designed scientifically.The equipment framework was built by three-dimensional simulation,and then the design of dismantling and recycling equipment for junction boxes of waste crystal silicon photovoltaic modules was completed through the experimental test and data analysis.The experimental results show that the initial idea of the dismantling scheme is correct,and the structure is feasible.However,some problems were not considered.This study provides reliable data support for the subsequent equipment development and ensures the smooth development of the subsequent design work.
基金supported by the Biological Breeding-National Science and Technology Major Project(2023ZD04069)the National Natural Science Foundation of China(32230074 and 32470264)。
文摘Enhancing crop productivity and quality remains a paramount breeding objective to address the dual challenges of global population growth and escalating demand.Cereal endosperms,particularly in staple crops such as rice,wheat,and maize,constitute the world's primary source of human nutrition and animal feed.
基金supported by the National Natural Science Foundation of China(32302615,31872070,31830081&31701868)the Natural Science Foundation of Guangxi(2022JJA130045)+5 种基金the Municipal Science and Technology Project of Alar(Xinjiang)in 2022(2022XX5)the Fundamental Research Funds for the Central Universities(JCQY201901)the Seed Industry Promotion Project of Jiangsu(JBGS(2021)022)the Guidance Foundation of the Hainan Institute of Nanjing Agricultural University(NAUSYMS08)the Jiangsu Agriculture Science and Technology Innovation Fund(CX(22)2025)the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions,and the Earmarked Fund for China Agriculture Research System(CARS-28).
文摘Putrescine plays a role in superficial scald development during the cold storage of pear fruit.However,the molecular mechanism behind this phenomenon has not been un-fully clarified until recently.In this study,a conjoint analysis of metabolites and gene expression profiles in the putrescine-metabolic pathway of P.bretschneideri Rehd.fruit followed by experimental validation revealed that PbrADC1,forming a homodimer in the chloroplast,was involved in putrescine biosynthesis and thus fruit chilling resistance.Additionally,the substrate-binding residue Cys^(546)in PbrADC1,whose activity was modified by H_(2)O_(2),played a crucial role in arginine decarboxylation into agmatine.Through a combined analysis of the distribution of cis-acting elements in the PbrADC1 promoter as well as the expression profiles of related transcription factors(TFs),several TFs were identified as upstream regulators of PbrADC1 gene.Further investigation revealed that the nuclear PbrWRKY62 could directly bind to the W-box elements in the PbrADC1 promoter,activate its expression,enhance putrescine accumulation,and thus increase fruit chilling tolerance.In conclusion,our results suggest that the PbrWRKY62-PbrADC1 module is involved in the development of superficial scald in P.bretschneideri Rehd.fruit via regulating putrescine biosynthesis.Consequently,these findings could serve as valuable genetic resources for breeding scald-resistant pear fruit.