为解决业务运营支撑系统(business operating support system,BOSS)系统中排重的性能问题,提出了优化方案。在研究了传统排重和其它排重的基础上,根据排重的业务特点,提出放弃使用商业数据库而采用文件加内存的优化方案。运用数据分割...为解决业务运营支撑系统(business operating support system,BOSS)系统中排重的性能问题,提出了优化方案。在研究了传统排重和其它排重的基础上,根据排重的业务特点,提出放弃使用商业数据库而采用文件加内存的优化方案。运用数据分割思想提高并行处理度,采用B树批量插入方式维护历史信息,对其进行了性能分析;内存中采用节点信息表建立索引,实现了指针压缩,减少了缓存失配和TLB失配;采用独特的事务一致检查点技术简化实现了事务机制。模拟数据测试结果表明,在不占用更多内存的情况下,在一个进程中优化方案性能较传统方案提高了56%。展开更多
Flexible intracerebral probes for neural recording and electrical stimulation have been the focus of many research works to achieve better compliance with the surrounding tissue while minimizing rejection.Strategies h...Flexible intracerebral probes for neural recording and electrical stimulation have been the focus of many research works to achieve better compliance with the surrounding tissue while minimizing rejection.Strategies have been explored to find the best way to insert flexible probes into the brain while maintaining their flexibility once positioned.Here,we present a novel and versatile scalable batch fabrication approach to deliver ultrathin and flexible probes consisting of a silk-parylene bilayer.The biodegradable silk layer,whose degradation time is programmable,provides a temporary and programmable stiffener to allow the insertion of ultrathin parylene-based flexible devices.Our innovative and robust batch fabrication technology allows complete freedom over probe design in terms of materials,size,shape,and thickness.We demonstrate successful ex vivo insertion of the probe with acute high-fidelity recordings of epileptic seizures in field potentials as well as single-unit action potentials in mouse brain slices.Our novel technological solution for implanting ultraflexible devices in the brain while minimizing rejection risks shows high potential for use in both brain research and clinical therapies.展开更多
文摘为解决业务运营支撑系统(business operating support system,BOSS)系统中排重的性能问题,提出了优化方案。在研究了传统排重和其它排重的基础上,根据排重的业务特点,提出放弃使用商业数据库而采用文件加内存的优化方案。运用数据分割思想提高并行处理度,采用B树批量插入方式维护历史信息,对其进行了性能分析;内存中采用节点信息表建立索引,实现了指针压缩,减少了缓存失配和TLB失配;采用独特的事务一致检查点技术简化实现了事务机制。模拟数据测试结果表明,在不占用更多内存的情况下,在一个进程中优化方案性能较传统方案提高了56%。
基金The authors acknowledge funding from the Agence Nationale de la Recherche(ANR-19-CE19-0002-01 and ANR ANR-15-CE19-0006)This work was supported by the French RENATECH network。
文摘Flexible intracerebral probes for neural recording and electrical stimulation have been the focus of many research works to achieve better compliance with the surrounding tissue while minimizing rejection.Strategies have been explored to find the best way to insert flexible probes into the brain while maintaining their flexibility once positioned.Here,we present a novel and versatile scalable batch fabrication approach to deliver ultrathin and flexible probes consisting of a silk-parylene bilayer.The biodegradable silk layer,whose degradation time is programmable,provides a temporary and programmable stiffener to allow the insertion of ultrathin parylene-based flexible devices.Our innovative and robust batch fabrication technology allows complete freedom over probe design in terms of materials,size,shape,and thickness.We demonstrate successful ex vivo insertion of the probe with acute high-fidelity recordings of epileptic seizures in field potentials as well as single-unit action potentials in mouse brain slices.Our novel technological solution for implanting ultraflexible devices in the brain while minimizing rejection risks shows high potential for use in both brain research and clinical therapies.
