To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were ran...To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were randomized to receive rapid-acting or sustained-release gliclazide therapy for 12 weeks.展开更多
We propose a scheme to implement a two-qubit conditional quantum phase gate for the intracavity field via a single three-level ∧-type atom driven by two modes in a high-Q cavity. The quantum inforraation is encoded o...We propose a scheme to implement a two-qubit conditional quantum phase gate for the intracavity field via a single three-level ∧-type atom driven by two modes in a high-Q cavity. The quantum inforraation is encoded on the Fock states of the bimodal cavity. The gate＇s averaged fidelity is expected to reach 99.8%.展开更多
The evolution of a system state is derived based on the nonresonant interaction of a three-level ＂Λ＂ type atom with two cavity modes at a pair coherent state and two classic fields,and a cavity field state is analy...The evolution of a system state is derived based on the nonresonant interaction of a three-level ＂Λ＂ type atom with two cavity modes at a pair coherent state and two classic fields,and a cavity field state is analyzed in detail under conditional detecting.It is found that the quantized modified Bessel-Gaussian states as well as the superposition states consisting of the quantized vortex states with different weighted coefficients may be prepared through carefully preparing an initial atomic state and appropriately adjusting the interaction time.The scheme provides an additional choice to realize the two-mode quantized vortex state within the context of cavity quantum electrodynamics（QED）.展开更多
In a study on erythrocyte polyamine levels in 20 leukemia patients and 18 healthy individuals, following results were obtained. Putrescine(Pu) in ery-throcytes was nearly undetectable but in 2 AMoL patients; Spermidin...In a study on erythrocyte polyamine levels in 20 leukemia patients and 18 healthy individuals, following results were obtained. Putrescine(Pu) in ery-throcytes was nearly undetectable but in 2 AMoL patients; Spermidine(Spd) level in ALL was higher than the control volue (P<0.05), in AML (M1, M2) and APL the Spd level was in the range of control group (P>0.1), while that in AMoL and AMMoL was considerably lower as compared to control (P< 0.001); Spermine (Spm) level in all types of leukemia was increased (P<0.001); Spd/Spm ratio was significantly decreased, showing 1.525 in control group, 0.938 in ALL (P<0.025), 0.779 in AML (M1, M2) P< 0.01), 0.319 in APL (P<0.001) and 0.296 in AMoL & AMMoL (P<0.001), and the differences between the Spd/Spm ratio in AMoL and AMMoL and in ALL were noted (P<0.05). These results suggested that determination of erythrocyte polyamines in leukemia patients may be helpful in diagnosis, differential diagnosis and prognosis.展开更多
We make an empirical analysis of regional characteristics of influence factors of financial exclusion by using the data of types and levels of financial institutions in China from 1998 to 2012. The study shows that th...We make an empirical analysis of regional characteristics of influence factors of financial exclusion by using the data of types and levels of financial institutions in China from 1998 to 2012. The study shows that the number of financial institutions continues to increase,but with uneven distribution; the density of financial institutions increases steadily and the gap between the eastern regions and the Midwest is huge; the commercial banks of the eastern regions account for the highest proportion but the rate of basic outlets of the commercial bank is low,the rate of basic outlets of the rural institution bank is relatively higher,and the proportion of the Midwest rural banks is high. Even though the financial exclusion eases,large differences still exist in different areas and the situation is rather critical in rural areas,especially the financial exclusion in western rural areas is the worst. The economic development level,area scale,government expenditure,personal savings level,per capita consumption and educational level have different effects on financial exclusion. Accordingly,this paper puts forward the recommendations for coordinating the financial resource from all regions and reducing the regional financial exclusion.展开更多
BACKGROUND Thiopurine-induced leukopenia(TIL)is a life-threatening toxicity and occurs with a high frequency in the Asian population.Although nucleoside diphosphate-linked moiety X-type motif 15(NUDT15)variants signif...BACKGROUND Thiopurine-induced leukopenia(TIL)is a life-threatening toxicity and occurs with a high frequency in the Asian population.Although nucleoside diphosphate-linked moiety X-type motif 15(NUDT15)variants significantly improve the predictive sensitivity of TIL,more than 50%of cases of this toxicity cannot be predicted by this mutation.The potential use of the 6-thioguanine nucleotide(6TGN)level to predict TIL has been explored,but no decisive conclusion has been reached.Can we increase the predictive sensitivity based on 6TGN by subgrouping patients according to their NUDT15 R139C genotypes?AIM To determine the 6TGN cut-off levels after dividing patients into subgroups according to their NUDT15 R139C genotypes.METHODS Patients’clinical and epidemiological characteristics were collected from medical records from July 2014 to February 2017.NUDT15 R139C,thiopurine S methyltransferase,and 6TGN concentrations were measured.RESULTS A total of 411 Crohn’s disease patients were included.TIL was observed in 72 individuals with a median 6TGN level of 323.4 pmol/8×10^8 red blood cells(RBC),which was not different from that of patients without TIL(P=0.071).Then,we compared the 6TGN levels based on NUDT15 R139C.For CC(n=342)and CT(n=65)genotypes,the median 6TGN level in patients with TIL was significantly higher than that in patients without(474.8 vs 306.0 pmol/8×10^8 RBC,P=9.4×10-^5;291.7 vs 217.6 pmol/8×10^8 RBC,P=0.039,respectively).The four TT carriers developed TIL,with a median 6TGN concentration of 135.8 pmol/8×10^8 RBC.The 6TGN cut-off levels were 411.5 and 319.2 pmol/8×108 RBC for the CC and CT groups,respectively.CONCLUSION The predictive sensitivity of TIL based on 6TGN is dramatically increased after subgrouping according to NUDT15 R139C genotypes.Applying 6TGN cut-off levels to adjust thiopurine therapies based on NUDT15 is strongly recommended.展开更多
Localization of the three-level Λ-type atomic system interacting with two orthogonal standing-wave fields is proposed. Two equal and tunable peaks in the 2D plane are obtained by the detunings corresponding to the tw...Localization of the three-level Λ-type atomic system interacting with two orthogonal standing-wave fields is proposed. Two equal and tunable peaks in the 2D plane are obtained by the detunings corresponding to the two orthogonal standing-wave fields when the decreasing intensities of spontaneously generated coherence (SGC) arise in the three-level Λ-type atomic system, while one circular ring with shrinking radii in the 2D plane is obtained by the adjusted phases and wave vectors of the standing-wave fields when the increasing intensities of SGC occur in the three-level Λ-type atomic system. 2D atom localization with the single ring with shrinking radii realized by the multiple parametric manipulations demonstrated the flexibility for our scheme.展开更多
We investigate the influence of the field fluctuations to the emission photons of V-type three-level systems.The emission intensity I and Mandel＇s Q parameter show stochastic resonance with respect to the pure dephas...We investigate the influence of the field fluctuations to the emission photons of V-type three-level systems.The emission intensity I and Mandel＇s Q parameter show stochastic resonance with respect to the pure dephasing constantγp.The amplitude fluctuation of the field causes these systems to lose their coherence.On the other hand,the amplitude fluctuation provides a new interference method for these systems.The quantum beats are shown in the orthogonal system.展开更多
This paper proposes a scheme for the generation of entangled coherent states for two cavity modes. In the scheme a V-type three-level atom is sent through a two-mode cavity filled with a coherent field. After the atom...This paper proposes a scheme for the generation of entangled coherent states for two cavity modes. In the scheme a V-type three-level atom is sent through a two-mode cavity filled with a coherent field. After the atom cavity interaction and detection of the atomic state the cavity modes may evolve to a superposition of two-mode coherent states. As the scheme is based on resonant atom-cavity interaction, the required interaction time is short, which is important in view of the decoherence. Moreover, additional classical pulses are unnecessary before and after the atom-cavlty interaction.展开更多
We theoretically investigate the emission spectrum for a A-type three-level atom trapped in the node of a standing wave. We show that the atomic center-of-mass motion not only directly affects the peak number, peak po...We theoretically investigate the emission spectrum for a A-type three-level atom trapped in the node of a standing wave. We show that the atomic center-of-mass motion not only directly affects the peak number, peak position, and peak height in the atomic emission spectrum, but also influences the effects of the cavity field and the atomic initial state on atomic emission spectrum.展开更多
Busia and Kisii Central districts are areas in western Kenya that have repeatedly reported high levels of stunting growth in children and an increase in hepatocellular carcinoma (HCC);an aspect often positively associ...Busia and Kisii Central districts are areas in western Kenya that have repeatedly reported high levels of stunting growth in children and an increase in hepatocellular carcinoma (HCC);an aspect often positively associated with chronic exposure to aflatoxins especially through consumption of foods such as peanuts. The objectives of the study were to determine the incidence, types and levels of aflatoxin in different varieties of peanuts produced in Busia and Kisii Central districts. One hundred and two (102) peanuts samples were collected from farmers’ in each district. Aflatoxin types and levels of aflatoxins were analyzed using high performance liquid chromatography (HPLC) technique. All the peanuts samples from Kisii Central and 97.06% samples from Busia were contaminated with aflatoxins. However, aflatoxin was not detected in 2.94% of samples from Busia district. The levels of total aflatoxin ranges were 0.1 to 268 μg/kg and 1.63 to 591.1 μg/kg in peanuts from Busia and Kisii Central respectively. Majority of peanuts samples had levels within Kenya Bureau of Standards (KEBS) and European Union (EU) regulatory limits for total aflatoxins. Improved variety (Valencia red) had significantly lower aflatoxin contamination compared to local varieties (Uganda local red, Homabay local and Local red). Aflatoxins B1, B2, G1 and G2 were found in peanuts;B1 was the most predominant in both districts (t = 12.4, df = 3, P = 0.034). The levels of aflatoxins especially in peanuts from Kisii Central district were high (591.1 μg/kg) where 44.6% of samples analyzed were unfit for even animal feed (USFDA regulatory limit). An assessment on the levels of aflatoxins should be done by the relevant stakeholders in other key foods in the areas for example maize. The most lethal aflatoxin type B1 was found to be the most predominant peanuts from both districts of study. This calls for frequent aflatoxin screening of peanuts from the districts particularly aflatoxin type B.展开更多
Background The association of E670G polymorphism in the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene and serum lipid profiles is inconsistent in dif- ferent ethnic groups.Bai Ku Yao is a special subgroup...Background The association of E670G polymorphism in the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene and serum lipid profiles is inconsistent in dif- ferent ethnic groups.Bai Ku Yao is a special subgroup of the Yao minority in China.The present study was undertaken association of PCSK9 E670G polymorphism and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations.Methods A total of 649 subjects of Bai Ku Yao and 646 participants of Han Chinese were randomly selected from our previous stratified randomized cluster samples.Genotyping of the PCSK9 E670G polymorphism was performed by polymerase chain reaction and restriction fragment length polymorphism combined with gel electrophoresis,and then confirmed by direct sequencing. Results The levels of serum total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) and apolipoprotein(Apo) AI were lower in Bai Ku Yao than in Han(P【0.01 for all).The frequency of A and G alleles was 98.00%and 2.00%in Bai Ku Yao,and 95.20%and 4.80%in Han(P【0.01);respectively. The frequency of AA,AG and GG genotypes was 95.99%,4.01%and 0%in Bai Ku Yao,and 91.02%, 8.36%and 0.62%in Han(P【0.01);respectively.There were also significant differences in the genotypic and allelic frequencies between n and the ratio of ApoAI to ApoB in Han Chinese but not in Bai Ku Yao were different between the AA and AG/GG genotypes(P【0.05 for all).The G allele carriers had higher serum HDL-C and higher ApoAI to ApoB ratio than the G allele noncarriers.When serum lipid parameters in Han were analyzed according to sex,the G allele carriers had higher serum HDL and ApoAI levels in males (P【0.05),and lower ApoB level and higher ApoAI to ApoB ratio in females(P【0.05 for all).Multiple linear regression analysis showed that serum HDL-C levels were correlated with genotypes in both ethnic groups(P【0.05 each).Serum lipid parameters were also correlated with sex,age,body massindex,alcohol consumption,cigarette smoking,and blood pressure in both ethnic groups(P【0.05-0.001).Conclusions These results suggest that the PCSK9 E670G polymorphism is mainly associated with some serum lipid parameters in the Han population,both gender show different relations to different serum lipid parameters.The G allele carriers might have higher serum lipid profiles than the G allele noncarriers. ormal LDL-C(≤3.20 mmol/L) and high LDL-C subgroups (】 3.20 mmol/L,P【0.01;respectively) in Bai Ku Yao, and between normal ApoB(≤1.14 g/L) and high ApoB subgroups(】 1.14 g/L,P 【 0.01;respectively) in Han.展开更多
We study the features of electromagnetically induced transparency（EIT） in a single Λ-type three-level atom placed in a high-finesse cavity under the action of a coupling laser and a probe laser.Our calculations sho...We study the features of electromagnetically induced transparency（EIT） in a single Λ-type three-level atom placed in a high-finesse cavity under the action of a coupling laser and a probe laser.Our calculations show that three transparency windows appear when the pump strength is large enough.This can be explained by the residual pump in the cavity mostly resulting in energy splitting.The level ｜3 is split into four slightly different energy levels,and interference takes place between the excitation pathways.Furthermore,it is also shown that the frequencies of the EIT windows can be tuned by changing the coupling field detuning 2,and that the reflection profile is very sensitive to the cavity field detuning △c.展开更多
In the paper, we consider Moran-type sets E;given by sequences {a;};and{n;};. we prove that E;may be decompose into the disjoint union of level sets. Moreover,we define three type of equivalence between two dimension ...In the paper, we consider Moran-type sets E;given by sequences {a;};and{n;};. we prove that E;may be decompose into the disjoint union of level sets. Moreover,we define three type of equivalence between two dimension functions associated to two Morantype sets, respectively, and we classify Moran-type sets by these equivalent relations.展开更多
Introduction: Diabetes mellitus type 2 is a growing threat in developing countries already burdened with high levels of infectious disease. Screening the general population has debatable advantages. This study aims to...Introduction: Diabetes mellitus type 2 is a growing threat in developing countries already burdened with high levels of infectious disease. Screening the general population has debatable advantages. This study aims to determine whether spouses of patients with diabetes mellitus have higher random blood glucose (RBG) levels as well as the benefit of RBG testing as a targetted screening tool. Methodology: The survey employed a cross-sectional comparative study of spouses’ of diabetics and non-diabetics attending the general out-patient department of the LagosStateUniversityTeaching Hospital (LASUTH), Ikeja. A modified WHO STEPS Surveillance Instrument and a one-touch Glucometer were used to collect data. Blood pressures and BMI were measured and correlated to blood glucose levels. Results: Prevalence of high RBG was found to be 7% among spouses of diabetics and 3.3% among spouses of non-diabetic patients. Mean RBG was 5.57 mmol/L and 7.7 mmol/L within the age group 40 - 49 years and 50 - 59 years respectively among spouses of diabetic patients compared to 5.4 mmol/L and 5.5 mmol/L within the same age group among the spouses non-diabetics. Spouses of patients with diabetes mellitus had higher systolic and diastolic blood pressures and BMI compared to spouses of non-diabetics. Conclusion: Being male, married to a diabetic patient, lower educational levels and higher body mass index are significantly associated with higher random blood glucose in the spouses of diabetic patients. Random blood glucose measurements are an effective screening tool and spouses of diabetic patients can benefit from targeted screening in controlled clinical settings.展开更多
文摘To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were randomized to receive rapid-acting or sustained-release gliclazide therapy for 12 weeks.
基金Project supported by the National Natural Science Foundation of China （Grant No 10374025）.
文摘We propose a scheme to implement a two-qubit conditional quantum phase gate for the intracavity field via a single three-level ∧-type atom driven by two modes in a high-Q cavity. The quantum inforraation is encoded on the Fock states of the bimodal cavity. The gate＇s averaged fidelity is expected to reach 99.8%.
文摘The evolution of a system state is derived based on the nonresonant interaction of a three-level ＂Λ＂ type atom with two cavity modes at a pair coherent state and two classic fields,and a cavity field state is analyzed in detail under conditional detecting.It is found that the quantized modified Bessel-Gaussian states as well as the superposition states consisting of the quantized vortex states with different weighted coefficients may be prepared through carefully preparing an initial atomic state and appropriately adjusting the interaction time.The scheme provides an additional choice to realize the two-mode quantized vortex state within the context of cavity quantum electrodynamics（QED）.
文摘In a study on erythrocyte polyamine levels in 20 leukemia patients and 18 healthy individuals, following results were obtained. Putrescine(Pu) in ery-throcytes was nearly undetectable but in 2 AMoL patients; Spermidine(Spd) level in ALL was higher than the control volue (P<0.05), in AML (M1, M2) and APL the Spd level was in the range of control group (P>0.1), while that in AMoL and AMMoL was considerably lower as compared to control (P< 0.001); Spermine (Spm) level in all types of leukemia was increased (P<0.001); Spd/Spm ratio was significantly decreased, showing 1.525 in control group, 0.938 in ALL (P<0.025), 0.779 in AML (M1, M2) P< 0.01), 0.319 in APL (P<0.001) and 0.296 in AMoL & AMMoL (P<0.001), and the differences between the Spd/Spm ratio in AMoL and AMMoL and in ALL were noted (P<0.05). These results suggested that determination of erythrocyte polyamines in leukemia patients may be helpful in diagnosis, differential diagnosis and prognosis.
文摘We make an empirical analysis of regional characteristics of influence factors of financial exclusion by using the data of types and levels of financial institutions in China from 1998 to 2012. The study shows that the number of financial institutions continues to increase,but with uneven distribution; the density of financial institutions increases steadily and the gap between the eastern regions and the Midwest is huge; the commercial banks of the eastern regions account for the highest proportion but the rate of basic outlets of the commercial bank is low,the rate of basic outlets of the rural institution bank is relatively higher,and the proportion of the Midwest rural banks is high. Even though the financial exclusion eases,large differences still exist in different areas and the situation is rather critical in rural areas,especially the financial exclusion in western rural areas is the worst. The economic development level,area scale,government expenditure,personal savings level,per capita consumption and educational level have different effects on financial exclusion. Accordingly,this paper puts forward the recommendations for coordinating the financial resource from all regions and reducing the regional financial exclusion.
基金Supported by the National Natural Science Foundation of China,No.81573507,No.81473283,No.81173131,and No.81320108027Guangdong Provincial Key Laboratory Construction Foundation,No.2017B030314030+1 种基金The National Key Research and Development Program,No.2016YFC0905003the 111 Project,No.B16047
文摘BACKGROUND Thiopurine-induced leukopenia(TIL)is a life-threatening toxicity and occurs with a high frequency in the Asian population.Although nucleoside diphosphate-linked moiety X-type motif 15(NUDT15)variants significantly improve the predictive sensitivity of TIL,more than 50%of cases of this toxicity cannot be predicted by this mutation.The potential use of the 6-thioguanine nucleotide(6TGN)level to predict TIL has been explored,but no decisive conclusion has been reached.Can we increase the predictive sensitivity based on 6TGN by subgrouping patients according to their NUDT15 R139C genotypes?AIM To determine the 6TGN cut-off levels after dividing patients into subgroups according to their NUDT15 R139C genotypes.METHODS Patients’clinical and epidemiological characteristics were collected from medical records from July 2014 to February 2017.NUDT15 R139C,thiopurine S methyltransferase,and 6TGN concentrations were measured.RESULTS A total of 411 Crohn’s disease patients were included.TIL was observed in 72 individuals with a median 6TGN level of 323.4 pmol/8×10^8 red blood cells(RBC),which was not different from that of patients without TIL(P=0.071).Then,we compared the 6TGN levels based on NUDT15 R139C.For CC(n=342)and CT(n=65)genotypes,the median 6TGN level in patients with TIL was significantly higher than that in patients without(474.8 vs 306.0 pmol/8×10^8 RBC,P=9.4×10-^5;291.7 vs 217.6 pmol/8×10^8 RBC,P=0.039,respectively).The four TT carriers developed TIL,with a median 6TGN concentration of 135.8 pmol/8×10^8 RBC.The 6TGN cut-off levels were 411.5 and 319.2 pmol/8×108 RBC for the CC and CT groups,respectively.CONCLUSION The predictive sensitivity of TIL based on 6TGN is dramatically increased after subgrouping according to NUDT15 R139C genotypes.Applying 6TGN cut-off levels to adjust thiopurine therapies based on NUDT15 is strongly recommended.
文摘Localization of the three-level Λ-type atomic system interacting with two orthogonal standing-wave fields is proposed. Two equal and tunable peaks in the 2D plane are obtained by the detunings corresponding to the two orthogonal standing-wave fields when the decreasing intensities of spontaneously generated coherence (SGC) arise in the three-level Λ-type atomic system, while one circular ring with shrinking radii in the 2D plane is obtained by the adjusted phases and wave vectors of the standing-wave fields when the increasing intensities of SGC occur in the three-level Λ-type atomic system. 2D atom localization with the single ring with shrinking radii realized by the multiple parametric manipulations demonstrated the flexibility for our scheme.
基金supported by the National Natural Science Foundation of China(Grand Nos.91021009,21073110,and 11374191)the Natural Science Foundation of Shandong Province,China(Grant No.ZR2013AQ020)+1 种基金the Postdoctoral Science Foundation of China(Grant No.2013M531584)the Doctoral Program of Higher Education of China(Grant Nos.20130131110005 and 20130131120006)
文摘We investigate the influence of the field fluctuations to the emission photons of V-type three-level systems.The emission intensity I and Mandel＇s Q parameter show stochastic resonance with respect to the pure dephasing constantγp.The amplitude fluctuation of the field causes these systems to lose their coherence.On the other hand,the amplitude fluctuation provides a new interference method for these systems.The quantum beats are shown in the orthogonal system.
基金Project supported by the National Natural Science Foundation of China (Grant No 10674025)the Funds from Fuzhou University
文摘This paper proposes a scheme for the generation of entangled coherent states for two cavity modes. In the scheme a V-type three-level atom is sent through a two-mode cavity filled with a coherent field. After the atom cavity interaction and detection of the atomic state the cavity modes may evolve to a superposition of two-mode coherent states. As the scheme is based on resonant atom-cavity interaction, the required interaction time is short, which is important in view of the decoherence. Moreover, additional classical pulses are unnecessary before and after the atom-cavlty interaction.
文摘We theoretically investigate the emission spectrum for a A-type three-level atom trapped in the node of a standing wave. We show that the atomic center-of-mass motion not only directly affects the peak number, peak position, and peak height in the atomic emission spectrum, but also influences the effects of the cavity field and the atomic initial state on atomic emission spectrum.
文摘Busia and Kisii Central districts are areas in western Kenya that have repeatedly reported high levels of stunting growth in children and an increase in hepatocellular carcinoma (HCC);an aspect often positively associated with chronic exposure to aflatoxins especially through consumption of foods such as peanuts. The objectives of the study were to determine the incidence, types and levels of aflatoxin in different varieties of peanuts produced in Busia and Kisii Central districts. One hundred and two (102) peanuts samples were collected from farmers’ in each district. Aflatoxin types and levels of aflatoxins were analyzed using high performance liquid chromatography (HPLC) technique. All the peanuts samples from Kisii Central and 97.06% samples from Busia were contaminated with aflatoxins. However, aflatoxin was not detected in 2.94% of samples from Busia district. The levels of total aflatoxin ranges were 0.1 to 268 μg/kg and 1.63 to 591.1 μg/kg in peanuts from Busia and Kisii Central respectively. Majority of peanuts samples had levels within Kenya Bureau of Standards (KEBS) and European Union (EU) regulatory limits for total aflatoxins. Improved variety (Valencia red) had significantly lower aflatoxin contamination compared to local varieties (Uganda local red, Homabay local and Local red). Aflatoxins B1, B2, G1 and G2 were found in peanuts;B1 was the most predominant in both districts (t = 12.4, df = 3, P = 0.034). The levels of aflatoxins especially in peanuts from Kisii Central district were high (591.1 μg/kg) where 44.6% of samples analyzed were unfit for even animal feed (USFDA regulatory limit). An assessment on the levels of aflatoxins should be done by the relevant stakeholders in other key foods in the areas for example maize. The most lethal aflatoxin type B1 was found to be the most predominant peanuts from both districts of study. This calls for frequent aflatoxin screening of peanuts from the districts particularly aflatoxin type B.
文摘Background The association of E670G polymorphism in the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene and serum lipid profiles is inconsistent in dif- ferent ethnic groups.Bai Ku Yao is a special subgroup of the Yao minority in China.The present study was undertaken association of PCSK9 E670G polymorphism and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations.Methods A total of 649 subjects of Bai Ku Yao and 646 participants of Han Chinese were randomly selected from our previous stratified randomized cluster samples.Genotyping of the PCSK9 E670G polymorphism was performed by polymerase chain reaction and restriction fragment length polymorphism combined with gel electrophoresis,and then confirmed by direct sequencing. Results The levels of serum total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) and apolipoprotein(Apo) AI were lower in Bai Ku Yao than in Han(P【0.01 for all).The frequency of A and G alleles was 98.00%and 2.00%in Bai Ku Yao,and 95.20%and 4.80%in Han(P【0.01);respectively. The frequency of AA,AG and GG genotypes was 95.99%,4.01%and 0%in Bai Ku Yao,and 91.02%, 8.36%and 0.62%in Han(P【0.01);respectively.There were also significant differences in the genotypic and allelic frequencies between n and the ratio of ApoAI to ApoB in Han Chinese but not in Bai Ku Yao were different between the AA and AG/GG genotypes(P【0.05 for all).The G allele carriers had higher serum HDL-C and higher ApoAI to ApoB ratio than the G allele noncarriers.When serum lipid parameters in Han were analyzed according to sex,the G allele carriers had higher serum HDL and ApoAI levels in males (P【0.05),and lower ApoB level and higher ApoAI to ApoB ratio in females(P【0.05 for all).Multiple linear regression analysis showed that serum HDL-C levels were correlated with genotypes in both ethnic groups(P【0.05 each).Serum lipid parameters were also correlated with sex,age,body massindex,alcohol consumption,cigarette smoking,and blood pressure in both ethnic groups(P【0.05-0.001).Conclusions These results suggest that the PCSK9 E670G polymorphism is mainly associated with some serum lipid parameters in the Han population,both gender show different relations to different serum lipid parameters.The G allele carriers might have higher serum lipid profiles than the G allele noncarriers. ormal LDL-C(≤3.20 mmol/L) and high LDL-C subgroups (】 3.20 mmol/L,P【0.01;respectively) in Bai Ku Yao, and between normal ApoB(≤1.14 g/L) and high ApoB subgroups(】 1.14 g/L,P 【 0.01;respectively) in Han.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 11274148 and 10704031)the Basic Scientific Research Business Expenses of the Central University,China (Grant No. lzujbky-2010-75)the Open Project of Key Laboratory for Magnetism and Magnetic Materials of the Ministry of Education,Lanzhou University,China
文摘We study the features of electromagnetically induced transparency（EIT） in a single Λ-type three-level atom placed in a high-finesse cavity under the action of a coupling laser and a probe laser.Our calculations show that three transparency windows appear when the pump strength is large enough.This can be explained by the residual pump in the cavity mostly resulting in energy splitting.The level ｜3 is split into four slightly different energy levels,and interference takes place between the excitation pathways.Furthermore,it is also shown that the frequencies of the EIT windows can be tuned by changing the coupling field detuning 2,and that the reflection profile is very sensitive to the cavity field detuning △c.
基金supported by NSFC (11201152)supported by NSFC(11371148)+4 种基金STCSM(13dz2260400)FDPHEC(20120076120001)Fundamental Research Funds for the central Universities,scut(2012zz0073)Fundamental Research Funds for the Central Universities SCUT(D2154240)Guangdong Natural Science Foundation(2014A030313230)
文摘In the paper, we consider Moran-type sets E;given by sequences {a;};and{n;};. we prove that E;may be decompose into the disjoint union of level sets. Moreover,we define three type of equivalence between two dimension functions associated to two Morantype sets, respectively, and we classify Moran-type sets by these equivalent relations.
文摘Introduction: Diabetes mellitus type 2 is a growing threat in developing countries already burdened with high levels of infectious disease. Screening the general population has debatable advantages. This study aims to determine whether spouses of patients with diabetes mellitus have higher random blood glucose (RBG) levels as well as the benefit of RBG testing as a targetted screening tool. Methodology: The survey employed a cross-sectional comparative study of spouses’ of diabetics and non-diabetics attending the general out-patient department of the LagosStateUniversityTeaching Hospital (LASUTH), Ikeja. A modified WHO STEPS Surveillance Instrument and a one-touch Glucometer were used to collect data. Blood pressures and BMI were measured and correlated to blood glucose levels. Results: Prevalence of high RBG was found to be 7% among spouses of diabetics and 3.3% among spouses of non-diabetic patients. Mean RBG was 5.57 mmol/L and 7.7 mmol/L within the age group 40 - 49 years and 50 - 59 years respectively among spouses of diabetic patients compared to 5.4 mmol/L and 5.5 mmol/L within the same age group among the spouses non-diabetics. Spouses of patients with diabetes mellitus had higher systolic and diastolic blood pressures and BMI compared to spouses of non-diabetics. Conclusion: Being male, married to a diabetic patient, lower educational levels and higher body mass index are significantly associated with higher random blood glucose in the spouses of diabetic patients. Random blood glucose measurements are an effective screening tool and spouses of diabetic patients can benefit from targeted screening in controlled clinical settings.
