By the turn of the 21 st century,the significance of knowledge to be the key factor in urban and regional development is well established. However,it has been recently and in only a few studies that attempts have been...By the turn of the 21 st century,the significance of knowledge to be the key factor in urban and regional development is well established. However,it has been recently and in only a few studies that attempts have been made to identify the specific mechanism and institutional relationships,through which knowledge-based development actually takes place.This paper builds upon the "Triple Helix Model" (Etzkowitz & Klofsten,2005) where university,business and government have been introduced as the key factors behind any knowledge-based development.It refers to a case study of knowledge-based community development in Australia's Smart State Queensland-and examines the role of the "Triple Helix" in the interaction between local and regional level.It shows the central role of the community as an innovation base for the interaction among the key factors and suggests a promotion for a Quadruple Helix Model where community is as important as business,university and government in the new economy.The paper concludes that knowledge-based development will not promote unless all four factors-community,business,university,government-work together.展开更多
Reversible data hiding(RDH)enables secret data embedding while preserving complete cover image recovery,making it crucial for applications requiring image integrity.The pixel value ordering(PVO)technique used in multi...Reversible data hiding(RDH)enables secret data embedding while preserving complete cover image recovery,making it crucial for applications requiring image integrity.The pixel value ordering(PVO)technique used in multi-stego images provides good image quality but often results in low embedding capability.To address these challenges,this paper proposes a high-capacity RDH scheme based on PVO that generates three stego images from a single cover image.The cover image is partitioned into non-overlapping blocks with pixels sorted in ascending order.Four secret bits are embedded into each block’s maximum pixel value,while three additional bits are embedded into the second-largest value when the pixel difference exceeds a predefined threshold.A similar embedding strategy is also applied to the minimum side of the block,including the second-smallest pixel value.This design enables each block to embed up to 14 bits of secret data.Experimental results demonstrate that the proposed method achieves significantly higher embedding capacity and improved visual quality compared to existing triple-stego RDH approaches,advancing the field of reversible steganography.展开更多
Tau plays a crucial role in several neurodegenerative diseases,collectively referred to as tauopathies.Therefore,targeting potential pathological changes in tau could enable useful therapeutic interventions.However,ta...Tau plays a crucial role in several neurodegenerative diseases,collectively referred to as tauopathies.Therefore,targeting potential pathological changes in tau could enable useful therapeutic interventions.However,tau is not an easy target because it dynamically interacts with microtubules and other cellular components,which presents a challenge for tau-targeted drugs.New cellular models could aid the development of mechanism-based tau-targeted therapies.展开更多
Correction to:Journal of Forestry Research(2025)36:124 https://doi.org/10.1007/s11676-025-01918-8 In this article the author’s name Yasutomo Hoshika was incorrectly written as Yasutoma Hoshika.The original article ha...Correction to:Journal of Forestry Research(2025)36:124 https://doi.org/10.1007/s11676-025-01918-8 In this article the author’s name Yasutomo Hoshika was incorrectly written as Yasutoma Hoshika.The original article has been corrected.展开更多
Federated Learning(FL)enables joint training over distributed devices without data exchange but is highly vulnerable to attacks by adversaries in the form of model poisoning and malicious update injection.This work pr...Federated Learning(FL)enables joint training over distributed devices without data exchange but is highly vulnerable to attacks by adversaries in the form of model poisoning and malicious update injection.This work proposes Secured-FL,a blockchain-based defensive framework that combines smart contract-based authentication,clustering-driven outlier elimination,and dynamic threshold adjustment to defend against adversarial attacks.The framework was implemented on a private Ethereum network with a Proof-of-Authority consensus algorithm to ensure tamper-resistant and auditable model updates.Large-scale simulation on the Cyber Data dataset,under up to 50%malicious client settings,demonstrates Secured-FL achieves 6%-12%higher accuracy,9%-15%lower latency,and approximately 14%less computational expense compared to the PPSS benchmark framework.Additional tests,including confusion matrices,ROC and Precision-Recall curves,and ablation tests,confirm the interpretability and robustness of the defense.Tests for scalability also show consistent performance up to 500 clients,affirming appropriateness to reasonably large deployments.These results make Secured-FL a feasible,adversarially resilient FL paradigm with promising potential for application in smart cities,medicine,and other mission-critical IoT deployments.展开更多
The original online version of this article was revised:Several errors occurred in the published version of the article.These have now been corrected as follows:Page 2,section"2.2 Laser Texturing Procedure of Sur...The original online version of this article was revised:Several errors occurred in the published version of the article.These have now been corrected as follows:Page 2,section"2.2 Laser Texturing Procedure of Surfaces",line 2:The device name was corrected from"YDFLP-E-50-M8"to"YDFLP-50-M8."Page 3,Section 2.4:The phrase"95%confidence interval"has been corrected to"95%confidence level."Page 3,Figure 1 caption:The phrase"fandg"has been corrected to"f and g."The order"C4 and C12"has been reversed to"C12 and C4,"in accordance with the display order in the figure.Page 4,Figure reference:The phrase"Figs.4c and d"has been corrected to"Figs.5b and c."Page 5,paragraph starting with"The ANOVA results are presented...":The phrase"95%confidence interval"has been corrected to"95%confidence level."展开更多
Hebei Province has incorporated targeted assistance services for people with disabilities into livelihood projects,upgrading the quality and efficiency of support services for disadvantaged groups.THE living and nursi...Hebei Province has incorporated targeted assistance services for people with disabilities into livelihood projects,upgrading the quality and efficiency of support services for disadvantaged groups.THE living and nursing allowances provided by the Chinese government for people with disabilities who are unable to work are not only important components of China’s social security system which provide for the needs of its disabled,but also show China’s ability to guarantee the basic living standard and social fairness and justice for this group of people.展开更多
The brain atlas,or parcellation-delineating spatial partitions,organizes the brain's structure and function[1].The spatial arrangements of highly heterogeneous landscapes represent specialized functional regions f...The brain atlas,or parcellation-delineating spatial partitions,organizes the brain's structure and function[1].The spatial arrangements of highly heterogeneous landscapes represent specialized functional regions for investigating their interactions.Early efforts to parcellate the mammalian brain,using histological cytoarchitecture and myeloarchitecture,as well as recent in vivo magnetic resonance imaging(MRl)[2,3],have primarily involved cortical areas,subcortical structures,and cerebellar nuclei.Human brain parcellations primarily focus on grey matter(GM),which purposefully excludes white matter(WM),hindering the development of next-generation brain atlases.展开更多
Remote driving,an emergent technology enabling remote operations of vehicles,presents a significant challenge in transmitting large volumes of image data to a central server.This requirement outpaces the capacity of t...Remote driving,an emergent technology enabling remote operations of vehicles,presents a significant challenge in transmitting large volumes of image data to a central server.This requirement outpaces the capacity of traditional communication methods.To tackle this,we propose a novel framework using semantic communications,through a region of interest semantic segmentation method,to reduce the communication costs by transmitting meaningful semantic information rather than bit-wise data.To solve the knowledge base inconsistencies inherent in semantic communications,we introduce a blockchain-based edge-assisted system for managing diverse and geographically varied semantic segmentation knowledge bases.This system not only ensures the security of data through the tamper-resistant nature of blockchain but also leverages edge computing for efficient management.Additionally,the implementation of blockchain sharding handles differentiated knowledge bases for various tasks,thus boosting overall blockchain efficiency.Experimental results show a great reduction in latency by sharding and an increase in model accuracy,confirming our framework's effectiveness.展开更多
Objective: To develop a best-evidence-based optimal nutrition management plan for patients with chronic heart failure, apply it in clinical practice, and evaluate its effectiveness. Methods: Use the KTA knowledge tran...Objective: To develop a best-evidence-based optimal nutrition management plan for patients with chronic heart failure, apply it in clinical practice, and evaluate its effectiveness. Methods: Use the KTA knowledge translation model to guide evidence-based practice in nutrition management, and compare the nutritional status, cardiac function status, quality of life, and quality review indicators of chronic heart failure patients before and after the application of evidence. Results: After the application of evidence, the nutritional status indicators (MNA-SF score, albumin, hemoglobin) of two groups of heart failure patients significantly increased compared to before the application of evidence, with statistically significant differences (p Conclusion: The KTA knowledge translation model provides methodological guidance for the implementation of evidence-based practice for heart failure patients. This evidence-based practice project is beneficial for improving the outcomes of malnutrition in chronic heart failure patients and is conducive to standardizing nursing pathways, thereby promoting the improvement of nursing quality.展开更多
In this paper, the knowledge based enterprise is considered as an organism, which possesses a set of capabilities. The organizational structure model of knowledge based enterprise organism is described in order to pos...In this paper, the knowledge based enterprise is considered as an organism, which possesses a set of capabilities. The organizational structure model of knowledge based enterprise organism is described in order to possess the essential capacity set. A dynamic capacity set is defined and analyzed based on the definition of the growth and development for knowledge based enterprise organism. The structure of the capacity base, a subset of the capacity set, is optimized for different periods of the organism ...展开更多
Bacterial blight(BB),caused by Xanthomonas oryzae pathovar oryzae(Xoo),poses a significant threat to rice production,particularly in Asia and West Africa.Breeding resistance against BB in elite rice varieties is cruci...Bacterial blight(BB),caused by Xanthomonas oryzae pathovar oryzae(Xoo),poses a significant threat to rice production,particularly in Asia and West Africa.Breeding resistance against BB in elite rice varieties is crucial to advancing rice breeding program and supporting smallholder farmers.Transcription Activator-Like effectors(TALes)are key virulence factors in Xoo,with some targeting the susceptibility(S)genes such as the sugar transporter SWEET genes in rice.Among these,SWEET14 is an important S gene,with its promoter bound by the TALe TalC which exists across all sequenced African Xoo isolates.In the present study,we utilized CRISPR/Cas9-based cytidine and adenine base editors to alter the effector binding element(EBE)of TalC in the promoter of SWEET14 in rice cultivars Kitaake,IR24,and Zhonghua 11.Mutations with C to T changes in EBE led to reduced SWEET14 induction by TalC-containing Xoo strains,resulting in resistance to African Xoo isolates reliant on TalC for virulence.Conversely,A to G changes retained SWEET14 inducibility and susceptibility to Xoo in edited lines.Importantly,no off-target mutations were detected at predicted sites,and the edited lines exhibited no obvious defects in major agronomic traits in Kitaake.These results underscore the effectiveness of base editing systems for both molecular biology research and crop improvement endeavors.展开更多
In the context of power generation companies, vast amounts of specialized data and expert knowledge have been accumulated. However, challenges such as data silos and fragmented knowledge hinder the effective utilizati...In the context of power generation companies, vast amounts of specialized data and expert knowledge have been accumulated. However, challenges such as data silos and fragmented knowledge hinder the effective utilization of this information. This study proposes a novel framework for intelligent Question-and-Answer (Q&A) systems based on Retrieval-Augmented Generation (RAG) to address these issues. The system efficiently acquires domain-specific knowledge by leveraging external databases, including Relational Databases (RDBs) and graph databases, without additional fine-tuning for Large Language Models (LLMs). Crucially, the framework integrates a Dynamic Knowledge Base Updating Mechanism (DKBUM) and a Weighted Context-Aware Similarity (WCAS) method to enhance retrieval accuracy and mitigate inherent limitations of LLMs, such as hallucinations and lack of specialization. Additionally, the proposed DKBUM dynamically adjusts knowledge weights within the database, ensuring that the most recent and relevant information is utilized, while WCAS refines the alignment between queries and knowledge items by enhanced context understanding. Experimental validation demonstrates that the system can generate timely, accurate, and context-sensitive responses, making it a robust solution for managing complex business logic in specialized industries.展开更多
Embodied visual exploration is critical for building intelligent visual agents. This paper presents the neural exploration with feature-based visual odometry and tracking-failure-reduction policy(Ne OR), a framework f...Embodied visual exploration is critical for building intelligent visual agents. This paper presents the neural exploration with feature-based visual odometry and tracking-failure-reduction policy(Ne OR), a framework for embodied visual exploration that possesses the efficient exploration capabilities of deep reinforcement learning(DRL)-based exploration policies and leverages feature-based visual odometry(VO) for more accurate mapping and positioning results. An improved local policy is also proposed to reduce tracking failures of feature-based VO in weakly textured scenes through a refined multi-discrete action space, keyframe fusion, and an auxiliary task. The experimental results demonstrate that Ne OR has better mapping and positioning accuracy compared to other entirely learning-based exploration frameworks and improves the robustness of feature-based VO by significantly reducing tracking failures in weakly textured scenes.展开更多
The wireless signals emitted by base stations serve as a vital link connecting people in today’s society and have been occupying an increasingly important role in real life.The development of the Internet of Things(I...The wireless signals emitted by base stations serve as a vital link connecting people in today’s society and have been occupying an increasingly important role in real life.The development of the Internet of Things(IoT)relies on the support of base stations,which provide a solid foundation for achieving a more intelligent way of living.In a specific area,achieving higher signal coverage with fewer base stations has become an urgent problem.Therefore,this article focuses on the effective coverage area of base station signals and proposes a novel Evolutionary Particle Swarm Optimization(EPSO)algorithm based on collective prediction,referred to herein as ECPPSO.Introducing a new strategy called neighbor-based evolution prediction(NEP)addresses the issue of premature convergence often encountered by PSO.ECPPSO also employs a strengthening evolution(SE)strategy to enhance the algorithm’s global search capability and efficiency,ensuring enhanced robustness and a faster convergence speed when solving complex optimization problems.To better adapt to the actual communication needs of base stations,this article conducts simulation experiments by changing the number of base stations.The experimental results demonstrate thatunder the conditionof 50 ormore base stations,ECPPSOconsistently achieves the best coverage rate exceeding 95%,peaking at 99.4400%when the number of base stations reaches 80.These results validate the optimization capability of the ECPPSO algorithm,proving its feasibility and effectiveness.Further ablative experiments and comparisons with other algorithms highlight the advantages of ECPPSO.展开更多
To further advance the development of the fluorescent dyes for latent fingerprint imaging,two triphenylamine-based Schiff base compounds containing a benzimidazole group(TPA-BZI)and a phenyl unit(TPA-Ph)were designed ...To further advance the development of the fluorescent dyes for latent fingerprint imaging,two triphenylamine-based Schiff base compounds containing a benzimidazole group(TPA-BZI)and a phenyl unit(TPA-Ph)were designed and synthesized.Photoluminescence experiments revealed that both compounds exhibited solvatochromism and intramolecular charge transfer(ICT)characteristics in six organic solvents.Additionally,they showed aggregation-induced emission(AIE)in CH_(3)OH/water mixtures and solid-state fluorescence.These phenomena were further elucidated through time-dependent density functional theory(TD-DFT)calculations.It was also found that the two compounds could be used for latent fingerprints imaging,and could easily distinguish the details of fingerprints from Ⅰ to Ⅲ levels,which could provide the preliminary evidence to match personal identification.展开更多
Magnesium-based materials,including magnesium alloys,have emerged as a promising class of biodegradable materials with potential applications in cancer therapy due to their unique properties,including biocompatibility...Magnesium-based materials,including magnesium alloys,have emerged as a promising class of biodegradable materials with potential applications in cancer therapy due to their unique properties,including biocompatibility,biodegradability,and the ability to modulate the tumor microenvironment.The main degradation products of magnesium alloys are magnesium ions(Mg^(2+)),hydrogen(H_(2)),and magnesium hydroxide(Mg(OH)_(2)).Magnesium ions can regulate tumor growth and metastasis by mediating the inflammatory response and oxidative stress,maintaining genomic stability,and affecting the tumor microenvironment.Similarly,hydrogen can inhibit tumorigenesis through antioxidant and anti-inflammatory properties.Moreover,Mg(OH)_(2) can alter the pH of the microenvironment,impacting tumorigenesis.Biodegradable magnesium alloys serve various functions in clinical applications,including,but not limited to,bonefixation,coronary stents,and drug carriers.Nonetheless,the anti-tumor mechanism associated with magnesium-based materials has not been thoroughly investigated.This review provides a comprehensive overview of the current state of magnesium-based therapies for cancer.It highlights the mechanisms of action,identifies the challenges that must be addressed,and discusses prospects for oncological applications.展开更多
Two new complexes,[Zn_(2)(L1)(HL1)(NO_(3))]·CH_(3)OH(1)and[Zn_(3)(L2)(L3)_(3)Cl]·CH_(3)OH(2),were successfully synthesized by‘one-pot’method based on cinnoline-3-ylhydrazine ligand and zinc with 2-hydroxy-...Two new complexes,[Zn_(2)(L1)(HL1)(NO_(3))]·CH_(3)OH(1)and[Zn_(3)(L2)(L3)_(3)Cl]·CH_(3)OH(2),were successfully synthesized by‘one-pot’method based on cinnoline-3-ylhydrazine ligand and zinc with 2-hydroxy-4-methoxybenzaldehyde and 2-hydroxy-3-methoxybenzaldehyde ligands,respectively,where H_(2)L1=5-methoxy-2-(phthalazin-1-ylhydrazonomethyl)-phenol,H_(2)L2=2-methoxy-6-(phthalazin-1-yl-hydrazonomethyl)-phenol,HL3=2-(1,8-dihydro-[1,2,4]triazolo[3,4-α]phthalazin-3-yl)-6-methoxy-phenol.Complexes 1 and 2 were characterized by infrared spectroscopy,elemental analysis,single-crystal X-ray diffraction,powder X-ray diffraction,etc.It is worth noting that the cinnolin-3-yl-hydrazine ligand and 2-hydroxy-3-methoxybenzaldehyde form two types of Schiff bases(H_(2)L2 and HL3)when in situ reacting and coordinating with Zn(Ⅱ),and HL3 also has two coordination modes.In addition,the fluorescence performance showed that complex 1 can achieve selective and sensitive sensing of Al^(3+)in water with a detection limit of 6.37μmol·L^(-1).CCDC:2413978,1;2413979,2.展开更多
To increase efficiency in fierce competition,it is necessary and urgent to improve the standard of production planning for shipbuilding.The construction of curved blocks is the bottleneck to improve the efficiency of ...To increase efficiency in fierce competition,it is necessary and urgent to improve the standard of production planning for shipbuilding.The construction of curved blocks is the bottleneck to improve the efficiency of shipbuilding.Thus it is a key breakthrough for higher shipbuilding productivity to study the curved block production.By analyzing the scheduling problem in curved blocks production,we propose an intelligent curved block production scheduling method and its system based on a knowledge base,and show the main process of the system.The functions of the system include data management,assembly plan generation,plan adjustment,and plan evaluation.In order to deal with the actual situation and inherit the empirical knowledge,the system extracts some rules to control block selecting,algorithm selection,and evaluation thresholds to build a production decision-making knowledge base in the curved block scheduling system.The proposed knowledge base could be referred and modified by users,especially after a few interactions between the users and the knowledge base.The final assembly plan can be visualized and evaluated to facilitate the observation of plan implementation and effects of the decisions in the process.Finally,the system is verified by a large shipyard in Shanghai using real data and the results illustrate that the proposed method can perform the knowledge-based scheduling for curved blocks construction effectively.展开更多
文摘By the turn of the 21 st century,the significance of knowledge to be the key factor in urban and regional development is well established. However,it has been recently and in only a few studies that attempts have been made to identify the specific mechanism and institutional relationships,through which knowledge-based development actually takes place.This paper builds upon the "Triple Helix Model" (Etzkowitz & Klofsten,2005) where university,business and government have been introduced as the key factors behind any knowledge-based development.It refers to a case study of knowledge-based community development in Australia's Smart State Queensland-and examines the role of the "Triple Helix" in the interaction between local and regional level.It shows the central role of the community as an innovation base for the interaction among the key factors and suggests a promotion for a Quadruple Helix Model where community is as important as business,university and government in the new economy.The paper concludes that knowledge-based development will not promote unless all four factors-community,business,university,government-work together.
基金funded by University of Transport and Communications(UTC)under grant number T2025-CN-004.
文摘Reversible data hiding(RDH)enables secret data embedding while preserving complete cover image recovery,making it crucial for applications requiring image integrity.The pixel value ordering(PVO)technique used in multi-stego images provides good image quality but often results in low embedding capability.To address these challenges,this paper proposes a high-capacity RDH scheme based on PVO that generates three stego images from a single cover image.The cover image is partitioned into non-overlapping blocks with pixels sorted in ascending order.Four secret bits are embedded into each block’s maximum pixel value,while three additional bits are embedded into the second-largest value when the pixel difference exceeds a predefined threshold.A similar embedding strategy is also applied to the minimum side of the block,including the second-smallest pixel value.This design enables each block to embed up to 14 bits of secret data.Experimental results demonstrate that the proposed method achieves significantly higher embedding capacity and improved visual quality compared to existing triple-stego RDH approaches,advancing the field of reversible steganography.
文摘Tau plays a crucial role in several neurodegenerative diseases,collectively referred to as tauopathies.Therefore,targeting potential pathological changes in tau could enable useful therapeutic interventions.However,tau is not an easy target because it dynamically interacts with microtubules and other cellular components,which presents a challenge for tau-targeted drugs.New cellular models could aid the development of mechanism-based tau-targeted therapies.
文摘Correction to:Journal of Forestry Research(2025)36:124 https://doi.org/10.1007/s11676-025-01918-8 In this article the author’s name Yasutomo Hoshika was incorrectly written as Yasutoma Hoshika.The original article has been corrected.
文摘Federated Learning(FL)enables joint training over distributed devices without data exchange but is highly vulnerable to attacks by adversaries in the form of model poisoning and malicious update injection.This work proposes Secured-FL,a blockchain-based defensive framework that combines smart contract-based authentication,clustering-driven outlier elimination,and dynamic threshold adjustment to defend against adversarial attacks.The framework was implemented on a private Ethereum network with a Proof-of-Authority consensus algorithm to ensure tamper-resistant and auditable model updates.Large-scale simulation on the Cyber Data dataset,under up to 50%malicious client settings,demonstrates Secured-FL achieves 6%-12%higher accuracy,9%-15%lower latency,and approximately 14%less computational expense compared to the PPSS benchmark framework.Additional tests,including confusion matrices,ROC and Precision-Recall curves,and ablation tests,confirm the interpretability and robustness of the defense.Tests for scalability also show consistent performance up to 500 clients,affirming appropriateness to reasonably large deployments.These results make Secured-FL a feasible,adversarially resilient FL paradigm with promising potential for application in smart cities,medicine,and other mission-critical IoT deployments.
文摘The original online version of this article was revised:Several errors occurred in the published version of the article.These have now been corrected as follows:Page 2,section"2.2 Laser Texturing Procedure of Surfaces",line 2:The device name was corrected from"YDFLP-E-50-M8"to"YDFLP-50-M8."Page 3,Section 2.4:The phrase"95%confidence interval"has been corrected to"95%confidence level."Page 3,Figure 1 caption:The phrase"fandg"has been corrected to"f and g."The order"C4 and C12"has been reversed to"C12 and C4,"in accordance with the display order in the figure.Page 4,Figure reference:The phrase"Figs.4c and d"has been corrected to"Figs.5b and c."Page 5,paragraph starting with"The ANOVA results are presented...":The phrase"95%confidence interval"has been corrected to"95%confidence level."
文摘Hebei Province has incorporated targeted assistance services for people with disabilities into livelihood projects,upgrading the quality and efficiency of support services for disadvantaged groups.THE living and nursing allowances provided by the Chinese government for people with disabilities who are unable to work are not only important components of China’s social security system which provide for the needs of its disabled,but also show China’s ability to guarantee the basic living standard and social fairness and justice for this group of people.
基金supported by the National Natural Science Foundation of China(62473082,82202250,82121003,62036003,and 62333003)the Fundamental Research Funds for the Central Universities(ZYGX2022YGRH008 and ZYGX2024XJ054)the Medical-Engineering Cooperation Funds from the University of Electronic Science and Technology of China(ZYGX2021YGLH201).
文摘The brain atlas,or parcellation-delineating spatial partitions,organizes the brain's structure and function[1].The spatial arrangements of highly heterogeneous landscapes represent specialized functional regions for investigating their interactions.Early efforts to parcellate the mammalian brain,using histological cytoarchitecture and myeloarchitecture,as well as recent in vivo magnetic resonance imaging(MRl)[2,3],have primarily involved cortical areas,subcortical structures,and cerebellar nuclei.Human brain parcellations primarily focus on grey matter(GM),which purposefully excludes white matter(WM),hindering the development of next-generation brain atlases.
基金supported in part by the National Natural Science Foundation of China under Grant No.62062031in part by the MIC/SCOPE#JP235006102+2 种基金in part by JST ASPIRE Grant Number JPMJAP2325in part by ROIS NII Open Collaborative Research under Grant 24S0601in part by collaborative research with Toyota Motor Corporation,Japan。
文摘Remote driving,an emergent technology enabling remote operations of vehicles,presents a significant challenge in transmitting large volumes of image data to a central server.This requirement outpaces the capacity of traditional communication methods.To tackle this,we propose a novel framework using semantic communications,through a region of interest semantic segmentation method,to reduce the communication costs by transmitting meaningful semantic information rather than bit-wise data.To solve the knowledge base inconsistencies inherent in semantic communications,we introduce a blockchain-based edge-assisted system for managing diverse and geographically varied semantic segmentation knowledge bases.This system not only ensures the security of data through the tamper-resistant nature of blockchain but also leverages edge computing for efficient management.Additionally,the implementation of blockchain sharding handles differentiated knowledge bases for various tasks,thus boosting overall blockchain efficiency.Experimental results show a great reduction in latency by sharding and an increase in model accuracy,confirming our framework's effectiveness.
文摘Objective: To develop a best-evidence-based optimal nutrition management plan for patients with chronic heart failure, apply it in clinical practice, and evaluate its effectiveness. Methods: Use the KTA knowledge translation model to guide evidence-based practice in nutrition management, and compare the nutritional status, cardiac function status, quality of life, and quality review indicators of chronic heart failure patients before and after the application of evidence. Results: After the application of evidence, the nutritional status indicators (MNA-SF score, albumin, hemoglobin) of two groups of heart failure patients significantly increased compared to before the application of evidence, with statistically significant differences (p Conclusion: The KTA knowledge translation model provides methodological guidance for the implementation of evidence-based practice for heart failure patients. This evidence-based practice project is beneficial for improving the outcomes of malnutrition in chronic heart failure patients and is conducive to standardizing nursing pathways, thereby promoting the improvement of nursing quality.
文摘In this paper, the knowledge based enterprise is considered as an organism, which possesses a set of capabilities. The organizational structure model of knowledge based enterprise organism is described in order to possess the essential capacity set. A dynamic capacity set is defined and analyzed based on the definition of the growth and development for knowledge based enterprise organism. The structure of the capacity base, a subset of the capacity set, is optimized for different periods of the organism ...
基金supported by a sub-award to the University of Missouri from the Heinrich Heine University of Dusseldorf funded by the Bill&Melinda Gates Foundation(OPP1155704)(Bing Yang)and the China Scholar Council(Chenhao Li,as a joint Ph.D.student).
文摘Bacterial blight(BB),caused by Xanthomonas oryzae pathovar oryzae(Xoo),poses a significant threat to rice production,particularly in Asia and West Africa.Breeding resistance against BB in elite rice varieties is crucial to advancing rice breeding program and supporting smallholder farmers.Transcription Activator-Like effectors(TALes)are key virulence factors in Xoo,with some targeting the susceptibility(S)genes such as the sugar transporter SWEET genes in rice.Among these,SWEET14 is an important S gene,with its promoter bound by the TALe TalC which exists across all sequenced African Xoo isolates.In the present study,we utilized CRISPR/Cas9-based cytidine and adenine base editors to alter the effector binding element(EBE)of TalC in the promoter of SWEET14 in rice cultivars Kitaake,IR24,and Zhonghua 11.Mutations with C to T changes in EBE led to reduced SWEET14 induction by TalC-containing Xoo strains,resulting in resistance to African Xoo isolates reliant on TalC for virulence.Conversely,A to G changes retained SWEET14 inducibility and susceptibility to Xoo in edited lines.Importantly,no off-target mutations were detected at predicted sites,and the edited lines exhibited no obvious defects in major agronomic traits in Kitaake.These results underscore the effectiveness of base editing systems for both molecular biology research and crop improvement endeavors.
文摘In the context of power generation companies, vast amounts of specialized data and expert knowledge have been accumulated. However, challenges such as data silos and fragmented knowledge hinder the effective utilization of this information. This study proposes a novel framework for intelligent Question-and-Answer (Q&A) systems based on Retrieval-Augmented Generation (RAG) to address these issues. The system efficiently acquires domain-specific knowledge by leveraging external databases, including Relational Databases (RDBs) and graph databases, without additional fine-tuning for Large Language Models (LLMs). Crucially, the framework integrates a Dynamic Knowledge Base Updating Mechanism (DKBUM) and a Weighted Context-Aware Similarity (WCAS) method to enhance retrieval accuracy and mitigate inherent limitations of LLMs, such as hallucinations and lack of specialization. Additionally, the proposed DKBUM dynamically adjusts knowledge weights within the database, ensuring that the most recent and relevant information is utilized, while WCAS refines the alignment between queries and knowledge items by enhanced context understanding. Experimental validation demonstrates that the system can generate timely, accurate, and context-sensitive responses, making it a robust solution for managing complex business logic in specialized industries.
基金supported by the National Natural Science Foundation of China (No.62202137)the China Postdoctoral Science Foundation (No.2023M730599)the Zhejiang Provincial Natural Science Foundation of China (No.LMS25F020009)。
文摘Embodied visual exploration is critical for building intelligent visual agents. This paper presents the neural exploration with feature-based visual odometry and tracking-failure-reduction policy(Ne OR), a framework for embodied visual exploration that possesses the efficient exploration capabilities of deep reinforcement learning(DRL)-based exploration policies and leverages feature-based visual odometry(VO) for more accurate mapping and positioning results. An improved local policy is also proposed to reduce tracking failures of feature-based VO in weakly textured scenes through a refined multi-discrete action space, keyframe fusion, and an auxiliary task. The experimental results demonstrate that Ne OR has better mapping and positioning accuracy compared to other entirely learning-based exploration frameworks and improves the robustness of feature-based VO by significantly reducing tracking failures in weakly textured scenes.
基金supported by the National Natural Science Foundation of China(Nos.62272418,62102058)Basic Public Welfare Research Program of Zhejiang Province(No.LGG18E050011)the Major Open Project of Key Laboratory for Advanced Design and Intelligent Computing of the Ministry of Education under Grant ADIC2023ZD001,National Undergraduate Training Program on Innovation and Entrepreneurship(No.202410345054).
文摘The wireless signals emitted by base stations serve as a vital link connecting people in today’s society and have been occupying an increasingly important role in real life.The development of the Internet of Things(IoT)relies on the support of base stations,which provide a solid foundation for achieving a more intelligent way of living.In a specific area,achieving higher signal coverage with fewer base stations has become an urgent problem.Therefore,this article focuses on the effective coverage area of base station signals and proposes a novel Evolutionary Particle Swarm Optimization(EPSO)algorithm based on collective prediction,referred to herein as ECPPSO.Introducing a new strategy called neighbor-based evolution prediction(NEP)addresses the issue of premature convergence often encountered by PSO.ECPPSO also employs a strengthening evolution(SE)strategy to enhance the algorithm’s global search capability and efficiency,ensuring enhanced robustness and a faster convergence speed when solving complex optimization problems.To better adapt to the actual communication needs of base stations,this article conducts simulation experiments by changing the number of base stations.The experimental results demonstrate thatunder the conditionof 50 ormore base stations,ECPPSOconsistently achieves the best coverage rate exceeding 95%,peaking at 99.4400%when the number of base stations reaches 80.These results validate the optimization capability of the ECPPSO algorithm,proving its feasibility and effectiveness.Further ablative experiments and comparisons with other algorithms highlight the advantages of ECPPSO.
文摘To further advance the development of the fluorescent dyes for latent fingerprint imaging,two triphenylamine-based Schiff base compounds containing a benzimidazole group(TPA-BZI)and a phenyl unit(TPA-Ph)were designed and synthesized.Photoluminescence experiments revealed that both compounds exhibited solvatochromism and intramolecular charge transfer(ICT)characteristics in six organic solvents.Additionally,they showed aggregation-induced emission(AIE)in CH_(3)OH/water mixtures and solid-state fluorescence.These phenomena were further elucidated through time-dependent density functional theory(TD-DFT)calculations.It was also found that the two compounds could be used for latent fingerprints imaging,and could easily distinguish the details of fingerprints from Ⅰ to Ⅲ levels,which could provide the preliminary evidence to match personal identification.
文摘Magnesium-based materials,including magnesium alloys,have emerged as a promising class of biodegradable materials with potential applications in cancer therapy due to their unique properties,including biocompatibility,biodegradability,and the ability to modulate the tumor microenvironment.The main degradation products of magnesium alloys are magnesium ions(Mg^(2+)),hydrogen(H_(2)),and magnesium hydroxide(Mg(OH)_(2)).Magnesium ions can regulate tumor growth and metastasis by mediating the inflammatory response and oxidative stress,maintaining genomic stability,and affecting the tumor microenvironment.Similarly,hydrogen can inhibit tumorigenesis through antioxidant and anti-inflammatory properties.Moreover,Mg(OH)_(2) can alter the pH of the microenvironment,impacting tumorigenesis.Biodegradable magnesium alloys serve various functions in clinical applications,including,but not limited to,bonefixation,coronary stents,and drug carriers.Nonetheless,the anti-tumor mechanism associated with magnesium-based materials has not been thoroughly investigated.This review provides a comprehensive overview of the current state of magnesium-based therapies for cancer.It highlights the mechanisms of action,identifies the challenges that must be addressed,and discusses prospects for oncological applications.
文摘Two new complexes,[Zn_(2)(L1)(HL1)(NO_(3))]·CH_(3)OH(1)and[Zn_(3)(L2)(L3)_(3)Cl]·CH_(3)OH(2),were successfully synthesized by‘one-pot’method based on cinnoline-3-ylhydrazine ligand and zinc with 2-hydroxy-4-methoxybenzaldehyde and 2-hydroxy-3-methoxybenzaldehyde ligands,respectively,where H_(2)L1=5-methoxy-2-(phthalazin-1-ylhydrazonomethyl)-phenol,H_(2)L2=2-methoxy-6-(phthalazin-1-yl-hydrazonomethyl)-phenol,HL3=2-(1,8-dihydro-[1,2,4]triazolo[3,4-α]phthalazin-3-yl)-6-methoxy-phenol.Complexes 1 and 2 were characterized by infrared spectroscopy,elemental analysis,single-crystal X-ray diffraction,powder X-ray diffraction,etc.It is worth noting that the cinnolin-3-yl-hydrazine ligand and 2-hydroxy-3-methoxybenzaldehyde form two types of Schiff bases(H_(2)L2 and HL3)when in situ reacting and coordinating with Zn(Ⅱ),and HL3 also has two coordination modes.In addition,the fluorescence performance showed that complex 1 can achieve selective and sensitive sensing of Al^(3+)in water with a detection limit of 6.37μmol·L^(-1).CCDC:2413978,1;2413979,2.
基金the China High-Tech Ship Project of the Ministry of Industry and Information Technology(No.2021-51(MC-202032-Z08))。
文摘To increase efficiency in fierce competition,it is necessary and urgent to improve the standard of production planning for shipbuilding.The construction of curved blocks is the bottleneck to improve the efficiency of shipbuilding.Thus it is a key breakthrough for higher shipbuilding productivity to study the curved block production.By analyzing the scheduling problem in curved blocks production,we propose an intelligent curved block production scheduling method and its system based on a knowledge base,and show the main process of the system.The functions of the system include data management,assembly plan generation,plan adjustment,and plan evaluation.In order to deal with the actual situation and inherit the empirical knowledge,the system extracts some rules to control block selecting,algorithm selection,and evaluation thresholds to build a production decision-making knowledge base in the curved block scheduling system.The proposed knowledge base could be referred and modified by users,especially after a few interactions between the users and the knowledge base.The final assembly plan can be visualized and evaluated to facilitate the observation of plan implementation and effects of the decisions in the process.Finally,the system is verified by a large shipyard in Shanghai using real data and the results illustrate that the proposed method can perform the knowledge-based scheduling for curved blocks construction effectively.
