Aim: To evaluate the joint action of phoxim and fenvalerate on the reproductive function in male Sprague-Dawley rats. Methods: The 2×2 factorial analysis experiment was used in the study. The pesticides were oral...Aim: To evaluate the joint action of phoxim and fenvalerate on the reproductive function in male Sprague-Dawley rats. Methods: The 2×2 factorial analysis experiment was used in the study. The pesticides were orally given at daily doses of phoxim (Pho) 8.2 nig/kg, fenvalerate (Fen) 3.3 mg/kg and Pho 8.2+Fen 3,3 mg/kg (Pho:Fen = 5:2), 5 days a week for 60 days. Sperm motility was measured with computer-assisted sperm motility analysis (CASA) and daily sperm production estimated. Immunoenzymatic method and electron microscopy were used to evaluate the serum testosterone and the testicular morphology, respectively. Results: There were significant decreases in sperm motility parameters in the treated animals, including straight line velocity (VSL), beat cross frequency (BCF), linearity (LIN) and straightness (STR). After treated with Fen, significant decreases in VSL, LIN and STR were demonstrated. Significant decreases of daily sperm production were seen in animals treated with Pho and Pho+Fen in comparison with the controls. Serum testosterone levels were not significantly changed in the treated groups. Factorial ANOVA showed that no significant interactions were noted between Pho and Fen in sperm motility, sperm production and serum testosterone. Both the single and mixed pesticides caused various degrees of testicular lesions, involving vacuolation of endoplasmic reticulum and necrosis of Sertoli cells. Conclusion: The pesticides may cause sperm motility changes and testicular lesions in male rats. The action of Pho and Fen may be additive.展开更多
Understanding the unstable evolution of railway slopes is the premise for preventing slope failure and ensuring the safe operation of trains.However,as two major factors affecting the stability of railway slopes,few s...Understanding the unstable evolution of railway slopes is the premise for preventing slope failure and ensuring the safe operation of trains.However,as two major factors affecting the stability of railway slopes,few scholars have explored the unstable evolution of railway slopes under the joint action of rainfall-vibration.Based on the model test of sandy soil slope,the unstable evolution process of slope under locomotive vibration,rainfall,and rainfall-vibration joint action conditions was simulated in this paper.By comparing and analyzing the variation trends of soil pressure and water content of slope under these conditions,the change laws of pore pressure under the influence of vibration and rainfall were explored.The main control factors affecting the stability of slope structure under the joint action conditions were further defined.Combined with the slope failure phenomena under these three conditions,the causes of slope instability resulting from each leading factor were clarified.Finally,according to the above conclusions,the unstable evolution of the slope under the rainfall-vibration joint action was determined.The test results show that the unstable evolution process of sandy soil slope,under the rainfall-vibration joint action,can be divided into:rainfall erosion cracking,vibration promotion penetrating,and slope instability sliding three stages.In the process of slope unstable evolution,rainfall and vibration play the roles of inducing and promoting slide respectively.In addition,the deep cracks,which are the premise for the formation of the sliding surface,and the violent irregular fluctuation of soil pressure,which reflects the near penetration of the sliding surface,constitute the instability characteristics of the railway slope together.This paper reveals the unstable evolution of sandy soil slopes under the joint action of rainfall-vibration,hoping to provide the theoretical basis for the early warning and prevention technology of railway slopes.展开更多
The joint action between chlorsulfuron and haloxyfop R was evaluated by bioassay with wheat and corn,respectivly.The dose response curve derived from wheat bioassay showed that the inhibition of haloxyfop R to whea...The joint action between chlorsulfuron and haloxyfop R was evaluated by bioassay with wheat and corn,respectivly.The dose response curve derived from wheat bioassay showed that the inhibition of haloxyfop R to wheat root growth wasn't affected by the increasing rate of chlorsulfuron.It indicated that chlorsulfuron had no antagonism to haloxyfop R.Meanwhile,the variation analysis of corn bioassay indicated that these two herbicides had joint action on inhibition to corn primary root growth.The joint action was evaluated as additive action by using Isobole Method.So chlorsulfuron and haloxyfop R could be used as tank mixture.展开更多
The joint meeting mechanism for the National Human Rights Action Plan(NHRAP)is a multi-faceted mechanism which unifies political,legislative,administrative,judicial and social sectors.It undertakes the responsibility ...The joint meeting mechanism for the National Human Rights Action Plan(NHRAP)is a multi-faceted mechanism which unifies political,legislative,administrative,judicial and social sectors.It undertakes the responsibility of formulating,implementing,supervising and evaluating the NHRAP,promotes mutual learning,exchange and competition among member units in the protection of human rights.Over the ten years since it was established,it has proved to be a successful innovative mechanism for protecting human rights that is in line with China’s national conditions.In order to improve the operation of the joint meeting mechanism the NHRAP,it is necessary to establish a more effective coordination mechanism within the joint meeting mechanism,and to subdivide the monitoring and evaluation functions into three levels.展开更多
This article deals with the investigation of the effects of seismic impacts on the design and dimensioning of structures in South Kivu. The starting point is the observation of an ambivalence that can be observed in t...This article deals with the investigation of the effects of seismic impacts on the design and dimensioning of structures in South Kivu. The starting point is the observation of an ambivalence that can be observed in the province, namely the non-consideration of seismic action in the study of structures by both professionals and researchers. The main objective of the study is to show the importance of dynamic analysis of structures in South Kivu. It adopts a meta-analytical approach referring to previous researches on South Kivu and proposes an efficient and optimal method. To arrive at the results, we use Eurocode 7 and 8. In addition, we conducted static analysis using the Coulomb method and dynamic analysis using the Mononobe-Okabe method and compared the results. At Nyabibwe, the results showed that we have a deviation of 24.47% for slip stability, 12.038% for overturning stability and 9.677% for stability against punching through a weight wall.展开更多
Study on the avoidance response of Penaeus chinensis to heavy metals (Pb, Cr, Zn) and heavy metal mixtures (Pb-Cr, Pb-Zn) is carred out using a Y-model avoidance apparatus. The concentrations calculated to induce 50% ...Study on the avoidance response of Penaeus chinensis to heavy metals (Pb, Cr, Zn) and heavy metal mixtures (Pb-Cr, Pb-Zn) is carred out using a Y-model avoidance apparatus. The concentrations calculated to induce 50% avoidance rate byPenaeus chinensis are 11.4, 33.2 and 238. 1 mg/L for Pb, Cr and Zn, respectively. Mixtures of Pb-Cr and Pb-Zn produce additive effect in the avoidance test using Penaeus chinesis. But when the mixed Pb-Zn solution has 0.5 toxic unit Pb and 0.5 toxic unit Zn, the mixture seems to have synergistic effect.展开更多
极区船舶与海冰发生挤压碰撞时常伴随着极地低温,考虑极地低温与冰载荷联合作用时对船舶舷侧极限承载能力的影响。首先,采用VOF(Volume of Fluid)模型研究在仅受环境温度影响下船舶舷侧垂向温度分布,水线至二甲板处受环境温度与海水温...极区船舶与海冰发生挤压碰撞时常伴随着极地低温,考虑极地低温与冰载荷联合作用时对船舶舷侧极限承载能力的影响。首先,采用VOF(Volume of Fluid)模型研究在仅受环境温度影响下船舶舷侧垂向温度分布,水线至二甲板处受环境温度与海水温度的影响产生明显的温度梯度,以此时的温度应力为基础,在船舶舷侧上施加冰载荷,细化冰载荷加载区域网格,通过两倍斜率法确定舷侧的极限承载能力,环境温度越低,其极限承载能力越小。改变冰载荷施加位置,对比有无强构件支撑时其极限承载能力的大小,结果表明强构件支撑能有效提高船体的极限承载能力。研究成果可为极区船舶结构强度校核提供参考。展开更多
文摘Aim: To evaluate the joint action of phoxim and fenvalerate on the reproductive function in male Sprague-Dawley rats. Methods: The 2×2 factorial analysis experiment was used in the study. The pesticides were orally given at daily doses of phoxim (Pho) 8.2 nig/kg, fenvalerate (Fen) 3.3 mg/kg and Pho 8.2+Fen 3,3 mg/kg (Pho:Fen = 5:2), 5 days a week for 60 days. Sperm motility was measured with computer-assisted sperm motility analysis (CASA) and daily sperm production estimated. Immunoenzymatic method and electron microscopy were used to evaluate the serum testosterone and the testicular morphology, respectively. Results: There were significant decreases in sperm motility parameters in the treated animals, including straight line velocity (VSL), beat cross frequency (BCF), linearity (LIN) and straightness (STR). After treated with Fen, significant decreases in VSL, LIN and STR were demonstrated. Significant decreases of daily sperm production were seen in animals treated with Pho and Pho+Fen in comparison with the controls. Serum testosterone levels were not significantly changed in the treated groups. Factorial ANOVA showed that no significant interactions were noted between Pho and Fen in sperm motility, sperm production and serum testosterone. Both the single and mixed pesticides caused various degrees of testicular lesions, involving vacuolation of endoplasmic reticulum and necrosis of Sertoli cells. Conclusion: The pesticides may cause sperm motility changes and testicular lesions in male rats. The action of Pho and Fen may be additive.
基金supported by the Major Research Plan of the National Natural Science Foundation of China(Grant No.42027806)the Key Programme of the Natural Science Foundation of China(Grant No.41630639)National Natural Science Foundation of China General Program(Grant No.42372324).
文摘Understanding the unstable evolution of railway slopes is the premise for preventing slope failure and ensuring the safe operation of trains.However,as two major factors affecting the stability of railway slopes,few scholars have explored the unstable evolution of railway slopes under the joint action of rainfall-vibration.Based on the model test of sandy soil slope,the unstable evolution process of slope under locomotive vibration,rainfall,and rainfall-vibration joint action conditions was simulated in this paper.By comparing and analyzing the variation trends of soil pressure and water content of slope under these conditions,the change laws of pore pressure under the influence of vibration and rainfall were explored.The main control factors affecting the stability of slope structure under the joint action conditions were further defined.Combined with the slope failure phenomena under these three conditions,the causes of slope instability resulting from each leading factor were clarified.Finally,according to the above conclusions,the unstable evolution of the slope under the rainfall-vibration joint action was determined.The test results show that the unstable evolution process of sandy soil slope,under the rainfall-vibration joint action,can be divided into:rainfall erosion cracking,vibration promotion penetrating,and slope instability sliding three stages.In the process of slope unstable evolution,rainfall and vibration play the roles of inducing and promoting slide respectively.In addition,the deep cracks,which are the premise for the formation of the sliding surface,and the violent irregular fluctuation of soil pressure,which reflects the near penetration of the sliding surface,constitute the instability characteristics of the railway slope together.This paper reveals the unstable evolution of sandy soil slopes under the joint action of rainfall-vibration,hoping to provide the theoretical basis for the early warning and prevention technology of railway slopes.
文摘The joint action between chlorsulfuron and haloxyfop R was evaluated by bioassay with wheat and corn,respectivly.The dose response curve derived from wheat bioassay showed that the inhibition of haloxyfop R to wheat root growth wasn't affected by the increasing rate of chlorsulfuron.It indicated that chlorsulfuron had no antagonism to haloxyfop R.Meanwhile,the variation analysis of corn bioassay indicated that these two herbicides had joint action on inhibition to corn primary root growth.The joint action was evaluated as additive action by using Isobole Method.So chlorsulfuron and haloxyfop R could be used as tank mixture.
基金the project researching Developments in the Theory and Practices of Socialist Human Rights with Chinese Characteristics since the Eighteenth National Congresssubproject of Marxist Theory Research and Development Project “researches on major basic theories on human rights”
文摘The joint meeting mechanism for the National Human Rights Action Plan(NHRAP)is a multi-faceted mechanism which unifies political,legislative,administrative,judicial and social sectors.It undertakes the responsibility of formulating,implementing,supervising and evaluating the NHRAP,promotes mutual learning,exchange and competition among member units in the protection of human rights.Over the ten years since it was established,it has proved to be a successful innovative mechanism for protecting human rights that is in line with China’s national conditions.In order to improve the operation of the joint meeting mechanism the NHRAP,it is necessary to establish a more effective coordination mechanism within the joint meeting mechanism,and to subdivide the monitoring and evaluation functions into three levels.
文摘This article deals with the investigation of the effects of seismic impacts on the design and dimensioning of structures in South Kivu. The starting point is the observation of an ambivalence that can be observed in the province, namely the non-consideration of seismic action in the study of structures by both professionals and researchers. The main objective of the study is to show the importance of dynamic analysis of structures in South Kivu. It adopts a meta-analytical approach referring to previous researches on South Kivu and proposes an efficient and optimal method. To arrive at the results, we use Eurocode 7 and 8. In addition, we conducted static analysis using the Coulomb method and dynamic analysis using the Mononobe-Okabe method and compared the results. At Nyabibwe, the results showed that we have a deviation of 24.47% for slip stability, 12.038% for overturning stability and 9.677% for stability against punching through a weight wall.
文摘Study on the avoidance response of Penaeus chinensis to heavy metals (Pb, Cr, Zn) and heavy metal mixtures (Pb-Cr, Pb-Zn) is carred out using a Y-model avoidance apparatus. The concentrations calculated to induce 50% avoidance rate byPenaeus chinensis are 11.4, 33.2 and 238. 1 mg/L for Pb, Cr and Zn, respectively. Mixtures of Pb-Cr and Pb-Zn produce additive effect in the avoidance test using Penaeus chinesis. But when the mixed Pb-Zn solution has 0.5 toxic unit Pb and 0.5 toxic unit Zn, the mixture seems to have synergistic effect.
文摘极区船舶与海冰发生挤压碰撞时常伴随着极地低温,考虑极地低温与冰载荷联合作用时对船舶舷侧极限承载能力的影响。首先,采用VOF(Volume of Fluid)模型研究在仅受环境温度影响下船舶舷侧垂向温度分布,水线至二甲板处受环境温度与海水温度的影响产生明显的温度梯度,以此时的温度应力为基础,在船舶舷侧上施加冰载荷,细化冰载荷加载区域网格,通过两倍斜率法确定舷侧的极限承载能力,环境温度越低,其极限承载能力越小。改变冰载荷施加位置,对比有无强构件支撑时其极限承载能力的大小,结果表明强构件支撑能有效提高船体的极限承载能力。研究成果可为极区船舶结构强度校核提供参考。
