Rivanol(RVN) binds to the double helical DNA with a high affinity. Strong hypochromism and appreciable red shifts in the absorption spectra can be observed when RVN binds to CT DNA. The results of absorption spectra, ...Rivanol(RVN) binds to the double helical DNA with a high affinity. Strong hypochromism and appreciable red shifts in the absorption spectra can be observed when RVN binds to CT DNA. The results of absorption spectra, KI quenching studies, fluorescence polarization measurements, competitive binding studies. and thermal denaturation experiments suggested that the interaction between RVN and DNA be intercalative.展开更多
文摘Rivanol(RVN) binds to the double helical DNA with a high affinity. Strong hypochromism and appreciable red shifts in the absorption spectra can be observed when RVN binds to CT DNA. The results of absorption spectra, KI quenching studies, fluorescence polarization measurements, competitive binding studies. and thermal denaturation experiments suggested that the interaction between RVN and DNA be intercalative.
