Rockbursts, which mainly affect mining roadways, are dynamic disasters arising from the surrounding rock under high stress. Understanding the interaction between supports and the surrounding rock is necessary for effe...Rockbursts, which mainly affect mining roadways, are dynamic disasters arising from the surrounding rock under high stress. Understanding the interaction between supports and the surrounding rock is necessary for effective rockburst control. In this study, the squeezing behavior of the surrounding rock is analyzed in rockburst roadways, and a mechanical model of rockbursts is established considering the dynamic support stress, thus deriving formulas and providing characteristic curves for describing the interaction between the support and surrounding rock. Design principles and parameters of supports for rockburst control are proposed. The results show that only when the geostress magnitude exceeds a critical value can it drive the formation of rockburst conditions. The main factors influencing the convergence response and rockburst occurrence around roadways are geostress, rock brittleness, uniaxial compressive strength, and roadway excavation size. Roadway support devices can play a role in controlling rockburst by suppressing the squeezing evolution of the surrounding rock towards instability points of rockburst. Further, the higher the strength and the longer the impact stroke of support devices with constant resistance, the more easily multiple balance points can be formed with the surrounding rock to control rockburst occurrence. Supports with long impact stroke allow adaptation to varying geostress levels around the roadway, aiding in rockburst control. The results offer a quantitative method for designing support systems for rockburst-prone roadways. The design criterion of supports is determined by the intersection between the convergence curve of the surrounding rock and the squeezing deformation curve of the support devices.展开更多
The epizoic diatoms,especifically those living at the body surface of copepods has not garnered sufficient attention.This study focuses on the copepod Pseudodiaptomus annandalei and three epizoic diatom species isolat...The epizoic diatoms,especifically those living at the body surface of copepods has not garnered sufficient attention.This study focuses on the copepod Pseudodiaptomus annandalei and three epizoic diatom species isolated from its body surface:Pseudofalcula hyalina,Haslea sp.,and Tabularia sp.The research explored the physiological and biochemical characteristics of diatoms under co cultivation conditions with P.annandalei and different species of epizoic diatoms,along with variations in copepod survival rates.Results reveal that the growth rate,cell density,and chlorophyll-a content of the three epizoic diatoms were enhanced by P.annandalei.The photosynthesis of epizoic diatoms,particularly the photochemical efficiency of PSⅡ(F_(v)/F_(m))of P.hyalina was positively influenced by P.annandalei.The impact of P.annandalei on biochemical compositions exhibited species-specific characteristics.Under co-culture conditions,the content of polysaccharides and proteins in the colloidal exopolymeric substance(CEPS)of P.hyalina and Haslea sp.increased,so did the intracellular protein content of Tabularia sp.The attachment of P.hyalina was most significantly influenced by P.annandalei,followed by Haslea sp.,and then Tabularia sp.,likely due to the increased uronic acid content of P.hyalina under co-culture conditions.Moreover,the three epizoic diatoms might have served as food sources for P.annandalei,as evidenced by the higher survival of copepods.The release of nitrate and phosphate from P.annandalei contributed to the nutrition for the growth of epizoic diatoms,indicating that the bottom-up effect resulting from P.annandalei excretion nutrition was greater than the top-down effect from predation.展开更多
Tropical cyclone-induced heavy precipitation(TCP)can have a detrimental impact on human productivity,causing significant economic losses and even human casualties in coastal countries every year.In this review article...Tropical cyclone-induced heavy precipitation(TCP)can have a detrimental impact on human productivity,causing significant economic losses and even human casualties in coastal countries every year.In this review article,the authors highlight the latest research developments in terms of ocean-atmosphere interactions and TCP,and identify the gaps where further research is required to enhance our understanding.The paper revolves around the following topics:(1)the characteristics of TCP over the ocean;(2)how air-sea interface processes,including sea surface temperature,sea-salt aerosols,and sea spray,influence TCP development;(3)the effects of TCP on the ocean;and(4)TCP changes in the context of global warming.In addition,directions and suggestions for future research toward a more comprehensive understanding of TCP-ocean interactions are discussed.Overall,this review summarizes the recent research progress and challenges in TCP-ocean interactions,and could serve as a guide for improvements in convective parameterization schemes and climate models toward predicting TCP distribution and intensity more accurately.展开更多
Verticillium wilt,caused by the infamous pathogen Verticillium dahliae,presents a primary constraint on cotton cul-tivation worldwide.The complexity of disease resistance in cotton and the largely unexplored interacti...Verticillium wilt,caused by the infamous pathogen Verticillium dahliae,presents a primary constraint on cotton cul-tivation worldwide.The complexity of disease resistance in cotton and the largely unexplored interaction dynamics between the cotton plant host and V.dahliae pathogen pose a crucial predicament for effectively managing cotton Verticillium wilt.Nevertheless,the most cost-effective approach to controlling this disease involves breeding and cul-tivating resistant cotton varieties,demanding a meticulous analysis of the mechanisms underlying cotton’s resistance to Verticillium wilt and the identification of pivotal genes.These aspects constitute focal points in disease-resistance breeding programs.In this review,we comprehensively discuss genetic inheritance associated with Verticillium wilt resistance in cotton,the advancements in molecular markers for disease resistance,the functional investiga-tion of resistance genes in cotton,the analysis of pathogenicity genes in V.dahliae,as well as the intricate interplay between cotton and this fungus.Moreover,we delve into the future prospects of cutting-edge research on cotton Verticillium wilt,aiming to proffer valuable insights for the effective management of this devastating fungus.展开更多
Submarine pipelines are critical infrastructures for offshore energy transport and communications. Understanding their structural response to near-field explosions is crucial for enhancing their blast resistance and o...Submarine pipelines are critical infrastructures for offshore energy transport and communications. Understanding their structural response to near-field explosions is crucial for enhancing their blast resistance and operational safety. This study presents a computational study on the interaction between explosion-induced bubbles and a seabed-mounted pipeline. A recently developed computational framework is employed, which couples a compressible fluid solver with a finite element structural solver via a partitioned procedure. An embedded boundary method and a level-set method are employed to handle the fluid-structure and gas-liquid interfaces. Using this framework, we analyze the flow field evolution, bubble dynamics, and transient pipe deformation. Two distinct response modes are identified: periodic oscillation under low-pressure loading and downward collapse triggered by high-pressure loading and bubble jet impact. Specifically, under high-pressure conditions, the pipe initially deforms inward, generating a localized high-pressure zone within the concave region. During structural rebound, the trapped fluid is expelled upward, giving rise to a bubble jet. Further parametric studies on the pipe's internal pressure, wall thickness, and support angle reveal several key insights. A higher internal pressure delays structural collapse, and a greater pipe thickness results in more uniform implosion morphologies. The support angle strongly influences the collapse dynamics, with the shortest collapse time occurring at 60 °. These findings offer new insights for the protective design of submarine pipelines.展开更多
This study proposed a novel experimental platform to conduct dynamic loading tests of a truncated model steel catenary riser(SCR)within the touchdown zone(TDZ).The facilities of the platform,including a soil tank,a lo...This study proposed a novel experimental platform to conduct dynamic loading tests of a truncated model steel catenary riser(SCR)within the touchdown zone(TDZ).The facilities of the platform,including a soil tank,a loading system,and a soil stirring system,are introduced in detail.A steel pipe with the same diameter as the in situ SCR has been used in the laboratory tests to investigate the vertical motion of the pipe and the effect of the trench on the lateral motion.As the amplitude of the vertical motion increases,the depth of the trench deepens,the bending moment range increases,and the excess pore water pressure at the bottom of the pipeline first accumulates and then dissipates during loading.The development trend of the trench depth and the influence of the soil strength on the SCR bending moment are also studied.During the test,a seabed trench develops,and its shape is similar to that of the in situ trench.展开更多
The study of ligand-receptor interactions is of great significance in food flavor perception.In this study,a computer simulation method was used to investigate the mechanism of interaction between umami peptides and T...The study of ligand-receptor interactions is of great significance in food flavor perception.In this study,a computer simulation method was used to investigate the mechanism of interaction between umami peptides and T1R1/T1R3-Venus-flytrap domain(VFT)receptor.The binding site,conformational changes,and binding free energy between umami peptides and T1R1/T1R3-VFT were analyzed through molecular modeling,molecular docking,and molecular dynamics simulations.The receptor model constructed using AlphaFold2 has the best rationality.The molecular docking results showed that umami peptides primarily bound to T1R1-VFT through hydrogen bonding,with key binding residues such as Thr149,Arg151,and Asp108.The binding of umami peptides led to a more stable complex system,and the positively charged amino acids contributed positively to the overall binding free energy.This study provides theoretical support for the development of a better understanding of the interaction between umami substances and the umami receptor.展开更多
Fe-based catalysts are widely used for CO_(2)hydrogenation to light olefins(C_(2–4)=);however,precise regulation of active phases and the balance between intermediate reactions remain significant challenges.Herein,we...Fe-based catalysts are widely used for CO_(2)hydrogenation to light olefins(C_(2–4)=);however,precise regulation of active phases and the balance between intermediate reactions remain significant challenges.Herein,we find that the addition of moderate amounts of Ti forms a strong interaction with Fe compositions,modulating the Fe_(3)O_(4)and Fe_(5)C_(2)contents.Enhanced interaction leads to an increased Fe_(5)C_(2)/Fe_(3)O_(4)ratio,which in turn enhances the adsorption of reactants and intermediates,promoting CO hydrogenation to unsaturated alkyl groups and facilitating C–C coupling.Furthermore,the strong Fe-Ti interaction induces the preferential growth of Fe_(5)C_(2)into prismatic structures that expose the(020),(–112),and(311)facets,forming compact active interfacial sites with Fe_(3)O_(4)nanoparticles.These facet and interfacial effects significantly promote the synergistic coupling of the reverse water gas shift and Fischer-Tropsch reactions.The optimized 3K/FeTi catalyst with the highest Fe_(5)C_(2)/Fe_(3)O_(4)ratio of 3.6 achieves a 52.2%CO_(2)conversion rate,with 44.5%selectivity for C2–4=and 9.5%for CO,and the highest space-time yield of 412.0 mg gcat^(–1)h^(–1)for C_(2–4)=.展开更多
Schizophrenia is characterized by psychotic symptoms,negative symptoms,and cognitive deficits,profoundly affecting individuals and their families.The etiology is multifactorial,involving genetic,endocrine,and immunolo...Schizophrenia is characterized by psychotic symptoms,negative symptoms,and cognitive deficits,profoundly affecting individuals and their families.The etiology is multifactorial,involving genetic,endocrine,and immunological risk factors.It is thought that schizophrenia is exclusively linked to alterations in brain structure and function,while the relationship between the brain and many organs may lack sufficient attention.Increasing evidence indicates abnormalities of the interactions between the brain and many organs in patients with schizophrenia.Inter-organ crosstalk affects the onset,course,and management of schizophrenia.Besides,the complex relationship between autonomic nervous system,endocrine system,and immune system further facilitates the development of schizophrenia.The present review summarizes the relationships between the brain and multiple organ systems in schizophrenia,providing new perspectives on the underlying pathophysiological mechanisms of schizophrenia.展开更多
The properties of a bound polaron in a parabolic quantum dot with weak electron-LO-phonon coupling under a Coulomb field are studied. The ground state energy of the bound polaron is derived by using a linear combinati...The properties of a bound polaron in a parabolic quantum dot with weak electron-LO-phonon coupling under a Coulomb field are studied. The ground state energy of the bound polaron is derived by using a linear combination operator and the perturbation method. The influence of the interaction between phonons with different wave vectors in the recoil process on the ground state energy of the bound polaron is discussed. Numerical calculations are performed,and the results show that the ground state energy increases significantly as the effective confinement length of the quantum dot decreases,considering of the interaction between phonons. When l0〉1.0, the influence of the interaction between phonons on the ground state energy cannot be ignored.展开更多
The effects of galvanic interaction between galena and pyrite on their flotation and electrochemical characters were studied by electrochemical,adsorption,flotation and FTIR techniques,respectively.Electrochemical tes...The effects of galvanic interaction between galena and pyrite on their flotation and electrochemical characters were studied by electrochemical,adsorption,flotation and FTIR techniques,respectively.Electrochemical tests indicate that galena is electrochemically more active than pyrite and serves as an anode in galvanic combination with pyrite.The galvanic current density from a mixture of galena and pyrite is 4 times as high as the self corrosion current density of galena,which indicates that the corrosion rate of galena is accelerated.Adsorption tests show that the adsorption of butyl xanthate on galena surface is enhanced,and affected by a combination of pyrite-galena mixtures and conditioning time.Compared with individual mineral particles,galvanic interaction reduces the floatability difference between galena and pyrite.The flotation recovery of galena decreases while that of pyrite increases when two minerals are mixed together due to the influence of galvanic interaction on the formation of hydrophilic/hydrophobic product.The FTIR results show that the formation of dixanthogen on pyrite surface is depressed due to the galvanic interaction.展开更多
There is an interaction between tacrolimus(TAC) and glucocorticoids where glucocorticoids is a known CYP3A4 and P-gp inducer.However, the dose of glucocorticoids reported is low but not pulse therapy.We retrospectivel...There is an interaction between tacrolimus(TAC) and glucocorticoids where glucocorticoids is a known CYP3A4 and P-gp inducer.However, the dose of glucocorticoids reported is low but not pulse therapy.We retrospectively studied 63 renal transplant recipients receiving TAC after transplantation.All the patients were classified as 500 mg(POD 1–3), 30 mg(POD 4–10), 25 mg(POD 11–17), 20 mg(POD 18–24), 15 mg(POD 25–31), 10 mg(POD 32–60) and 10 mg(POD 61–90).We recorded daily data for each patient from the day of transplantation until POD 90.There was no difference in TAC blood levels within the 3 months after transplantation in the glucocorticoids groups.However, the average daily dose of TAC was significantly lower by weekly reductions of 5 mg dose.The TAC daily dose was not changed from POD 1–4, but the blood concentrations of TAC were significantly lower after the glucocorticoid dose was changed from 500 mg to 30 mg.We demonstrated the induction effect of low-dose glucocorticoids on TAC in renal transplant recipients, and found that the high-dose of glucocorticoids might play a role in substrate competition.We proposed that monitoring of the blood concentrations of TAC was needed when the glucocorticoid dose was changed in the patient undergoing renal transplantation.展开更多
[Objective] This study aimed to analyze the interaction between genotype of flavonoids of barley grain and environment, to increase the flavonoid content of barley grain in cultivation and breeding. [Method] In this s...[Objective] This study aimed to analyze the interaction between genotype of flavonoids of barley grain and environment, to increase the flavonoid content of barley grain in cultivation and breeding. [Method] In this study, the content of cate- chin, myricetin, quercetin and kaempferol of barley grain planted in Kunming, Qujing and Baoshan were determined by HPLC, and the genotype, environment, genotype- environment interaction of the flavonoid content of barley grain were analyzed. [Result] According to the experimental results, the genotype variance, environmental variance and G x E interaction variance of catechin and kaempferol contents show the same trend： genotype variation 〉 environmental variation 〉 G × E interaction variation, which all reach a extremely significant level; the genotype variance, envi- ronmental variance and G × E interaction variance of quercetin and total flavonoid contents show the same trend： genetype variation 〉 G × E interaction variation 〉 environmental variation, which all reach a extremely significant level; the genotype variance and environmental variance of myricetin content both reach a extremely sig- nificant level, while the G × E interaction variance reaches a significant level, showing an order of genotype variation 〉 environmental variation 〉 G × E interaction variation; the genotype variance, environmental variance and G x E interaction vari- ance of total flavonoid content show an order of genotype variation 〉 environmental variation 〉 G × E interaction variation. Among different barley varieties, Ziguang- mangluoerling and Kuanyingdamai in Qujing, Kunming and Baoshan have relatively high content of quercetin, while other barley varieties barely contain any quercetin. The grains of Ziguangmangluoerling and Kuanyingdamai are purple, while the grains of other barley varieties are yellow. [Conclusion] Four main flavonoids and the total flavonoids of barley grain are mainly under genetic control and affected by genetic- environment interactions; the purple barley grains contain high content of quercetin.展开更多
A two-dimensional Reynolds-averaged Navier-Stokes solver is applied to analyze the aerodynamic behavior of the Shock/Boundary-Layer interaction of rocket with a boosted The K-ε turbulence model and a finite volume m...A two-dimensional Reynolds-averaged Navier-Stokes solver is applied to analyze the aerodynamic behavior of the Shock/Boundary-Layer interaction of rocket with a boosted The K-ε turbulence model and a finite volume method in a unstructured body-fitted curvilinear coordinates have been used. The results indicate that the separation and the reattachment occur in the Boundary-Layer of the main rocket because of the shock interaction. The shape of the booster nose effects the flow field obviously. In the case of the hemisphere booster nose the pressure has complicate distributions and the separation is very clear. The distance between the booster and main rocket has the evident effect on the flow field. If the distance is smaller the pressure coefficient is bigger the separation zone even the separation bubble occurs.展开更多
The model of dislocations was used to construct the model of grain boundary (GB) with pure rare earths, and rare earth elements and impurities. The influence of the interaction between rare earth elements and impuriti...The model of dislocations was used to construct the model of grain boundary (GB) with pure rare earths, and rare earth elements and impurities. The influence of the interaction between rare earth elements and impurities on the cohesive properties of 5.3° low angle GB of Fe was investigated by the recursion method. The calculated results of environment sensitive embeding energy( E ESE ) show that the preferential segregation of rare earth elements towards GBs exists. Calculations of bond order integrals (BOI) show that rare earth elements increase the cohesive strength of low angle GB, and impurities such as S, P weaken the intergranular cohesion of the GB. So rare earth element of proper quantity added in steel not only cleanses other harmful impurities off the GBs, but also enhances the intergranular cohesion. This elucidates the action mechanism of rare earth elements in steel from electronic level and offers theoretical evidence for applications of rare earth elements in steels.展开更多
In China, there are approximately 20 million people suffering from peripheral nerve injury and this number is increasing at a rate of 2 million per year. These patients cannot live or work independently and are a heav...In China, there are approximately 20 million people suffering from peripheral nerve injury and this number is increasing at a rate of 2 million per year. These patients cannot live or work independently and are a heavy responsibility on both family and society because of extreme disability and dysfunction caused by peripheral nerve injury （PNI）. Thus, repair of PNI has become a major public health issue in China.展开更多
A certain quantity of RE is dissolved in high-carbon steel. The dissolved RE not only segregates on grain boundary, but also exists in grains. It exists in cementite much more than in ferrite. RE makes the carbides sp...A certain quantity of RE is dissolved in high-carbon steel. The dissolved RE not only segregates on grain boundary, but also exists in grains. It exists in cementite much more than in ferrite. RE makes the carbides spheroidal and fine, and the carbides distribute uniformly. RE also changes the morphology of pearlite. By means of the analysis of Auger energy spectrum, we find that RE, which is dissolved in cementite, changes the composition and structure of cementite. In the case of higher content of RE and carbon, RE carbide can be formed.展开更多
Low energy ions exist widely in natural world, but people pay a little attention on. the interaction between low energy ions and matter, it is even more out of the question of studying on the relation of low energy io...Low energy ions exist widely in natural world, but people pay a little attention on. the interaction between low energy ions and matter, it is even more out of the question of studying on the relation of low energy ions and the complicated organism. The discovery of bioeffect induced by ion implantation has, however, opened a new branch in the field of ion beam application in life sciences. This paper reports recent advances in research on the role of low energy ions in Chemical synthesis of the biomolecules and application in genetic modification.展开更多
Starting from the variable separation approach, the algebraic soliton solution and the solution describing the interaction between line soliton and algebraic soliton are obtained by selecting appropriate seed solution...Starting from the variable separation approach, the algebraic soliton solution and the solution describing the interaction between line soliton and algebraic soliton are obtained by selecting appropriate seed solution for （2＋1）-dimensional ANNV equation. The behaviors of interactions are discussed in detail both analytically and graphically. It is shown that there are two kinds of singular interactions between line soliton and algebraic soliton： 1） the resonant interaction where the algebraic soliton propagates together with the line soliton and persists infinitely; 2） the extremely repulsive interaction where the algebraic soliton affects the motion of the line soliton infinitely apart.展开更多
A thermodynamic model has been built up for the interactions between molten Ti alloys and oxide molding materials in the way of decomposition and solution of molding materials, then the influences on the reaction free...A thermodynamic model has been built up for the interactions between molten Ti alloys and oxide molding materials in the way of decomposition and solution of molding materials, then the influences on the reaction free energy changes have been calculated and discussed.展开更多
基金funded by the National Natural Science Foundation of China (No. 52304133)the National Key R&D Program of China (No. 2022YFC3004605)the Department of Science and Technology of Liaoning Province (No. 2023-BS-083)。
文摘Rockbursts, which mainly affect mining roadways, are dynamic disasters arising from the surrounding rock under high stress. Understanding the interaction between supports and the surrounding rock is necessary for effective rockburst control. In this study, the squeezing behavior of the surrounding rock is analyzed in rockburst roadways, and a mechanical model of rockbursts is established considering the dynamic support stress, thus deriving formulas and providing characteristic curves for describing the interaction between the support and surrounding rock. Design principles and parameters of supports for rockburst control are proposed. The results show that only when the geostress magnitude exceeds a critical value can it drive the formation of rockburst conditions. The main factors influencing the convergence response and rockburst occurrence around roadways are geostress, rock brittleness, uniaxial compressive strength, and roadway excavation size. Roadway support devices can play a role in controlling rockburst by suppressing the squeezing evolution of the surrounding rock towards instability points of rockburst. Further, the higher the strength and the longer the impact stroke of support devices with constant resistance, the more easily multiple balance points can be formed with the surrounding rock to control rockburst occurrence. Supports with long impact stroke allow adaptation to varying geostress levels around the roadway, aiding in rockburst control. The results offer a quantitative method for designing support systems for rockburst-prone roadways. The design criterion of supports is determined by the intersection between the convergence curve of the surrounding rock and the squeezing deformation curve of the support devices.
基金Supported by the National Natural Science Foundation of China(No.42076114)the Second Batch of High-level Professional Groups of Vocational Colleges in Guangdong Province(No.GSPZYQ 2021004)the Guangxi Science and Technology Base and Talent Special Project(No.GUIKE AD 23026041)。
文摘The epizoic diatoms,especifically those living at the body surface of copepods has not garnered sufficient attention.This study focuses on the copepod Pseudodiaptomus annandalei and three epizoic diatom species isolated from its body surface:Pseudofalcula hyalina,Haslea sp.,and Tabularia sp.The research explored the physiological and biochemical characteristics of diatoms under co cultivation conditions with P.annandalei and different species of epizoic diatoms,along with variations in copepod survival rates.Results reveal that the growth rate,cell density,and chlorophyll-a content of the three epizoic diatoms were enhanced by P.annandalei.The photosynthesis of epizoic diatoms,particularly the photochemical efficiency of PSⅡ(F_(v)/F_(m))of P.hyalina was positively influenced by P.annandalei.The impact of P.annandalei on biochemical compositions exhibited species-specific characteristics.Under co-culture conditions,the content of polysaccharides and proteins in the colloidal exopolymeric substance(CEPS)of P.hyalina and Haslea sp.increased,so did the intracellular protein content of Tabularia sp.The attachment of P.hyalina was most significantly influenced by P.annandalei,followed by Haslea sp.,and then Tabularia sp.,likely due to the increased uronic acid content of P.hyalina under co-culture conditions.Moreover,the three epizoic diatoms might have served as food sources for P.annandalei,as evidenced by the higher survival of copepods.The release of nitrate and phosphate from P.annandalei contributed to the nutrition for the growth of epizoic diatoms,indicating that the bottom-up effect resulting from P.annandalei excretion nutrition was greater than the top-down effect from predation.
基金supported by the National Natural Science Foundation of China [grant numbers 42192552 and 42475011]。
文摘Tropical cyclone-induced heavy precipitation(TCP)can have a detrimental impact on human productivity,causing significant economic losses and even human casualties in coastal countries every year.In this review article,the authors highlight the latest research developments in terms of ocean-atmosphere interactions and TCP,and identify the gaps where further research is required to enhance our understanding.The paper revolves around the following topics:(1)the characteristics of TCP over the ocean;(2)how air-sea interface processes,including sea surface temperature,sea-salt aerosols,and sea spray,influence TCP development;(3)the effects of TCP on the ocean;and(4)TCP changes in the context of global warming.In addition,directions and suggestions for future research toward a more comprehensive understanding of TCP-ocean interactions are discussed.Overall,this review summarizes the recent research progress and challenges in TCP-ocean interactions,and could serve as a guide for improvements in convective parameterization schemes and climate models toward predicting TCP distribution and intensity more accurately.
基金supported by National Natural Science Foundation of China(32201752)Xinjiang Tianchi Talents Program (TCYC2023TP02)Key Project of the Natural Science Foundation of Xinjiang Production and Construction Corps (2024DA001)
文摘Verticillium wilt,caused by the infamous pathogen Verticillium dahliae,presents a primary constraint on cotton cul-tivation worldwide.The complexity of disease resistance in cotton and the largely unexplored interaction dynamics between the cotton plant host and V.dahliae pathogen pose a crucial predicament for effectively managing cotton Verticillium wilt.Nevertheless,the most cost-effective approach to controlling this disease involves breeding and cul-tivating resistant cotton varieties,demanding a meticulous analysis of the mechanisms underlying cotton’s resistance to Verticillium wilt and the identification of pivotal genes.These aspects constitute focal points in disease-resistance breeding programs.In this review,we comprehensively discuss genetic inheritance associated with Verticillium wilt resistance in cotton,the advancements in molecular markers for disease resistance,the functional investiga-tion of resistance genes in cotton,the analysis of pathogenicity genes in V.dahliae,as well as the intricate interplay between cotton and this fungus.Moreover,we delve into the future prospects of cutting-edge research on cotton Verticillium wilt,aiming to proffer valuable insights for the effective management of this devastating fungus.
基金supported by the National Key R&D Program of China(Grant No.2024YFC3013200)the Shenzhen Peacock Plan(Grant No.QD2023006C).
文摘Submarine pipelines are critical infrastructures for offshore energy transport and communications. Understanding their structural response to near-field explosions is crucial for enhancing their blast resistance and operational safety. This study presents a computational study on the interaction between explosion-induced bubbles and a seabed-mounted pipeline. A recently developed computational framework is employed, which couples a compressible fluid solver with a finite element structural solver via a partitioned procedure. An embedded boundary method and a level-set method are employed to handle the fluid-structure and gas-liquid interfaces. Using this framework, we analyze the flow field evolution, bubble dynamics, and transient pipe deformation. Two distinct response modes are identified: periodic oscillation under low-pressure loading and downward collapse triggered by high-pressure loading and bubble jet impact. Specifically, under high-pressure conditions, the pipe initially deforms inward, generating a localized high-pressure zone within the concave region. During structural rebound, the trapped fluid is expelled upward, giving rise to a bubble jet. Further parametric studies on the pipe's internal pressure, wall thickness, and support angle reveal several key insights. A higher internal pressure delays structural collapse, and a greater pipe thickness results in more uniform implosion morphologies. The support angle strongly influences the collapse dynamics, with the shortest collapse time occurring at 60 °. These findings offer new insights for the protective design of submarine pipelines.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.51879189 and 52071234).
文摘This study proposed a novel experimental platform to conduct dynamic loading tests of a truncated model steel catenary riser(SCR)within the touchdown zone(TDZ).The facilities of the platform,including a soil tank,a loading system,and a soil stirring system,are introduced in detail.A steel pipe with the same diameter as the in situ SCR has been used in the laboratory tests to investigate the vertical motion of the pipe and the effect of the trench on the lateral motion.As the amplitude of the vertical motion increases,the depth of the trench deepens,the bending moment range increases,and the excess pore water pressure at the bottom of the pipeline first accumulates and then dissipates during loading.The development trend of the trench depth and the influence of the soil strength on the SCR bending moment are also studied.During the test,a seabed trench develops,and its shape is similar to that of the in situ trench.
基金funded by the National Natural Science Foundation of China(32001824,31972198)supported by the Startup Fund for Young Faculty at SJTU(Shanghai Jiao Tong University)High Level Innovation Team and Distinguished Scholar Project of Guangxi Universities and Colleges(2020[6]).
文摘The study of ligand-receptor interactions is of great significance in food flavor perception.In this study,a computer simulation method was used to investigate the mechanism of interaction between umami peptides and T1R1/T1R3-Venus-flytrap domain(VFT)receptor.The binding site,conformational changes,and binding free energy between umami peptides and T1R1/T1R3-VFT were analyzed through molecular modeling,molecular docking,and molecular dynamics simulations.The receptor model constructed using AlphaFold2 has the best rationality.The molecular docking results showed that umami peptides primarily bound to T1R1-VFT through hydrogen bonding,with key binding residues such as Thr149,Arg151,and Asp108.The binding of umami peptides led to a more stable complex system,and the positively charged amino acids contributed positively to the overall binding free energy.This study provides theoretical support for the development of a better understanding of the interaction between umami substances and the umami receptor.
文摘Fe-based catalysts are widely used for CO_(2)hydrogenation to light olefins(C_(2–4)=);however,precise regulation of active phases and the balance between intermediate reactions remain significant challenges.Herein,we find that the addition of moderate amounts of Ti forms a strong interaction with Fe compositions,modulating the Fe_(3)O_(4)and Fe_(5)C_(2)contents.Enhanced interaction leads to an increased Fe_(5)C_(2)/Fe_(3)O_(4)ratio,which in turn enhances the adsorption of reactants and intermediates,promoting CO hydrogenation to unsaturated alkyl groups and facilitating C–C coupling.Furthermore,the strong Fe-Ti interaction induces the preferential growth of Fe_(5)C_(2)into prismatic structures that expose the(020),(–112),and(311)facets,forming compact active interfacial sites with Fe_(3)O_(4)nanoparticles.These facet and interfacial effects significantly promote the synergistic coupling of the reverse water gas shift and Fischer-Tropsch reactions.The optimized 3K/FeTi catalyst with the highest Fe_(5)C_(2)/Fe_(3)O_(4)ratio of 3.6 achieves a 52.2%CO_(2)conversion rate,with 44.5%selectivity for C2–4=and 9.5%for CO,and the highest space-time yield of 412.0 mg gcat^(–1)h^(–1)for C_(2–4)=.
基金Supported by Beijing Traditional Chinese Medicine Scientific and Technological Development Fund Project,No.BJZYYB-2023-66Beijing Natural Science Foundation,No.7212050the Capital’s Funds for Health Improvement and Research,No.2020-4-2126.
文摘Schizophrenia is characterized by psychotic symptoms,negative symptoms,and cognitive deficits,profoundly affecting individuals and their families.The etiology is multifactorial,involving genetic,endocrine,and immunological risk factors.It is thought that schizophrenia is exclusively linked to alterations in brain structure and function,while the relationship between the brain and many organs may lack sufficient attention.Increasing evidence indicates abnormalities of the interactions between the brain and many organs in patients with schizophrenia.Inter-organ crosstalk affects the onset,course,and management of schizophrenia.Besides,the complex relationship between autonomic nervous system,endocrine system,and immune system further facilitates the development of schizophrenia.The present review summarizes the relationships between the brain and multiple organ systems in schizophrenia,providing new perspectives on the underlying pathophysiological mechanisms of schizophrenia.
文摘The properties of a bound polaron in a parabolic quantum dot with weak electron-LO-phonon coupling under a Coulomb field are studied. The ground state energy of the bound polaron is derived by using a linear combination operator and the perturbation method. The influence of the interaction between phonons with different wave vectors in the recoil process on the ground state energy of the bound polaron is discussed. Numerical calculations are performed,and the results show that the ground state energy increases significantly as the effective confinement length of the quantum dot decreases,considering of the interaction between phonons. When l0〉1.0, the influence of the interaction between phonons on the ground state energy cannot be ignored.
基金Project(51274255)supported by the National Natural Science Foundation of ChinaProject supported by the Co-innovation Center for Clean and Efficient Utilization of Strategic Metal Mineral Resources,China
文摘The effects of galvanic interaction between galena and pyrite on their flotation and electrochemical characters were studied by electrochemical,adsorption,flotation and FTIR techniques,respectively.Electrochemical tests indicate that galena is electrochemically more active than pyrite and serves as an anode in galvanic combination with pyrite.The galvanic current density from a mixture of galena and pyrite is 4 times as high as the self corrosion current density of galena,which indicates that the corrosion rate of galena is accelerated.Adsorption tests show that the adsorption of butyl xanthate on galena surface is enhanced,and affected by a combination of pyrite-galena mixtures and conditioning time.Compared with individual mineral particles,galvanic interaction reduces the floatability difference between galena and pyrite.The flotation recovery of galena decreases while that of pyrite increases when two minerals are mixed together due to the influence of galvanic interaction on the formation of hydrophilic/hydrophobic product.The FTIR results show that the formation of dixanthogen on pyrite surface is depressed due to the galvanic interaction.
文摘There is an interaction between tacrolimus(TAC) and glucocorticoids where glucocorticoids is a known CYP3A4 and P-gp inducer.However, the dose of glucocorticoids reported is low but not pulse therapy.We retrospectively studied 63 renal transplant recipients receiving TAC after transplantation.All the patients were classified as 500 mg(POD 1–3), 30 mg(POD 4–10), 25 mg(POD 11–17), 20 mg(POD 18–24), 15 mg(POD 25–31), 10 mg(POD 32–60) and 10 mg(POD 61–90).We recorded daily data for each patient from the day of transplantation until POD 90.There was no difference in TAC blood levels within the 3 months after transplantation in the glucocorticoids groups.However, the average daily dose of TAC was significantly lower by weekly reductions of 5 mg dose.The TAC daily dose was not changed from POD 1–4, but the blood concentrations of TAC were significantly lower after the glucocorticoid dose was changed from 500 mg to 30 mg.We demonstrated the induction effect of low-dose glucocorticoids on TAC in renal transplant recipients, and found that the high-dose of glucocorticoids might play a role in substrate competition.We proposed that monitoring of the blood concentrations of TAC was needed when the glucocorticoid dose was changed in the patient undergoing renal transplantation.
基金Supported by National Barley Industrial Technology System of China(CARS-05)National Natural Science Foundation of China(No.31260326)~~
文摘[Objective] This study aimed to analyze the interaction between genotype of flavonoids of barley grain and environment, to increase the flavonoid content of barley grain in cultivation and breeding. [Method] In this study, the content of cate- chin, myricetin, quercetin and kaempferol of barley grain planted in Kunming, Qujing and Baoshan were determined by HPLC, and the genotype, environment, genotype- environment interaction of the flavonoid content of barley grain were analyzed. [Result] According to the experimental results, the genotype variance, environmental variance and G x E interaction variance of catechin and kaempferol contents show the same trend： genotype variation 〉 environmental variation 〉 G × E interaction variation, which all reach a extremely significant level; the genotype variance, envi- ronmental variance and G × E interaction variance of quercetin and total flavonoid contents show the same trend： genetype variation 〉 G × E interaction variation 〉 environmental variation, which all reach a extremely significant level; the genotype variance and environmental variance of myricetin content both reach a extremely sig- nificant level, while the G × E interaction variance reaches a significant level, showing an order of genotype variation 〉 environmental variation 〉 G × E interaction variation; the genotype variance, environmental variance and G x E interaction vari- ance of total flavonoid content show an order of genotype variation 〉 environmental variation 〉 G × E interaction variation. Among different barley varieties, Ziguang- mangluoerling and Kuanyingdamai in Qujing, Kunming and Baoshan have relatively high content of quercetin, while other barley varieties barely contain any quercetin. The grains of Ziguangmangluoerling and Kuanyingdamai are purple, while the grains of other barley varieties are yellow. [Conclusion] Four main flavonoids and the total flavonoids of barley grain are mainly under genetic control and affected by genetic- environment interactions; the purple barley grains contain high content of quercetin.
文摘A two-dimensional Reynolds-averaged Navier-Stokes solver is applied to analyze the aerodynamic behavior of the Shock/Boundary-Layer interaction of rocket with a boosted The K-ε turbulence model and a finite volume method in a unstructured body-fitted curvilinear coordinates have been used. The results indicate that the separation and the reattachment occur in the Boundary-Layer of the main rocket because of the shock interaction. The shape of the booster nose effects the flow field obviously. In the case of the hemisphere booster nose the pressure has complicate distributions and the separation is very clear. The distance between the booster and main rocket has the evident effect on the flow field. If the distance is smaller the pressure coefficient is bigger the separation zone even the separation bubble occurs.
文摘The model of dislocations was used to construct the model of grain boundary (GB) with pure rare earths, and rare earth elements and impurities. The influence of the interaction between rare earth elements and impurities on the cohesive properties of 5.3° low angle GB of Fe was investigated by the recursion method. The calculated results of environment sensitive embeding energy( E ESE ) show that the preferential segregation of rare earth elements towards GBs exists. Calculations of bond order integrals (BOI) show that rare earth elements increase the cohesive strength of low angle GB, and impurities such as S, P weaken the intergranular cohesion of the GB. So rare earth element of proper quantity added in steel not only cleanses other harmful impurities off the GBs, but also enhances the intergranular cohesion. This elucidates the action mechanism of rare earth elements in steel from electronic level and offers theoretical evidence for applications of rare earth elements in steels.
基金supported by grants from the National Program on Key Basic Research Project of China(973 Program),No.2014CB542200Program for Innovative Research Team in University of Ministry of Education of China,No.IRT1201+1 种基金the National Natural Science Foundation of China,No.31271284,31171150,81171146,30971526,31100860,31040043Program for New Century Excellent Talents in University of Ministry of Education of China,No.BMU20110270
文摘In China, there are approximately 20 million people suffering from peripheral nerve injury and this number is increasing at a rate of 2 million per year. These patients cannot live or work independently and are a heavy responsibility on both family and society because of extreme disability and dysfunction caused by peripheral nerve injury （PNI）. Thus, repair of PNI has become a major public health issue in China.
文摘A certain quantity of RE is dissolved in high-carbon steel. The dissolved RE not only segregates on grain boundary, but also exists in grains. It exists in cementite much more than in ferrite. RE makes the carbides spheroidal and fine, and the carbides distribute uniformly. RE also changes the morphology of pearlite. By means of the analysis of Auger energy spectrum, we find that RE, which is dissolved in cementite, changes the composition and structure of cementite. In the case of higher content of RE and carbon, RE carbide can be formed.
基金National Science & Technology Key ProgramNational Nature Science FOundation+1 种基金Chinese Academy of Sciences FoundationAnh
文摘Low energy ions exist widely in natural world, but people pay a little attention on. the interaction between low energy ions and matter, it is even more out of the question of studying on the relation of low energy ions and the complicated organism. The discovery of bioeffect induced by ion implantation has, however, opened a new branch in the field of ion beam application in life sciences. This paper reports recent advances in research on the role of low energy ions in Chemical synthesis of the biomolecules and application in genetic modification.
基金National Natural Science Foundation of China under Grant No.10675065the Science Research Foundation of the Education Department of Zhejiang Province under Grant No.20070979+1 种基金the Natural Science Foundation of Zhejiang Province under Grant No.Y604036the State Key Laboratory of Oil/Gas Reservoir Geology and Exploitation\PLN0402
文摘Starting from the variable separation approach, the algebraic soliton solution and the solution describing the interaction between line soliton and algebraic soliton are obtained by selecting appropriate seed solution for （2＋1）-dimensional ANNV equation. The behaviors of interactions are discussed in detail both analytically and graphically. It is shown that there are two kinds of singular interactions between line soliton and algebraic soliton： 1） the resonant interaction where the algebraic soliton propagates together with the line soliton and persists infinitely; 2） the extremely repulsive interaction where the algebraic soliton affects the motion of the line soliton infinitely apart.
基金This work was supported by Postdoctoral Foundation of Northwestern Polytechnical University and Science Research FOundation o
文摘A thermodynamic model has been built up for the interactions between molten Ti alloys and oxide molding materials in the way of decomposition and solution of molding materials, then the influences on the reaction free energy changes have been calculated and discussed.
