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Forging of silaoxycarbocyclics by interrupted Catellani reaction
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作者 Yu-Chen Fang Jia-He Chen +5 位作者 Mi-Zhuan Li Hui-Min Li Mei Bai Yong-Zheng Chen Zi-Wei Gao Wen-Yong Han 《Chinese Chemical Letters》 2025年第7期328-333,共6页
Catalytic syntheses of silaoxycarbocyclics from an interrupted Catellani reaction of 3-iodochromones with bridged olefins and octamethyl-1,4-dioxacyclohexasilane is described.This protocol involves the oxidative addit... Catalytic syntheses of silaoxycarbocyclics from an interrupted Catellani reaction of 3-iodochromones with bridged olefins and octamethyl-1,4-dioxacyclohexasilane is described.This protocol involves the oxidative addition of chromonyl-norbornyl-palladacycle generated through successive oxidative addition of Pd(0)to 3-iodochromones,migratory insertion of NBE and intramolecular ortho-C(sp^(2))-H activation to the tetrasilane,thus motivating a(4+6)annulation and ring expansion.The synthetic practicality of current strategy is further proved by the late-stage modification of pharmaceuticals and natural products,gram-scale experiments,as well as the transformations of functional groups of silaoxycarbocyclics. 展开更多
关键词 Ring expansion Chromonyl-norbornyl-palladacycle interrupted Catellani reaction Silaoxycarbocyclics
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Research Progress on Nursing Interruptions in the Operating Room
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作者 Yajing Ling Mingming Wang +3 位作者 Renmin Zhang Shuting Tang Yan Chen Peng Wang 《Journal of Clinical and Nursing Research》 2025年第9期295-303,共9页
In recent years,research on nursing interruptions has been conducted at various levels in emergency departments,intensive care units,hemodialysis centers,operating rooms,and sterilization and supply centers.Nursing in... In recent years,research on nursing interruptions has been conducted at various levels in emergency departments,intensive care units,hemodialysis centers,operating rooms,and sterilization and supply centers.Nursing interruptions are closely related to adverse nursing events,and interruptions in operating room nursing can significantly impact the success of a patient’s surgery.However,there is a lack of in-depth theoretical research on safety risk assessment and response decision-making by operating room nurses when faced with nursing interruptions.This article reviews the concept,current status,and impact of nursing interruptions in the operating room,analyzes the cognitive level,coping strategies,and negative emotions of operating room nurses,and elaborates on management strategies to provide references for research and management of nursing interruptions in the operating room. 展开更多
关键词 Operating room nursing Nursing interruptions Safety management
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Comparison between interrupted closure technique and traditional closure technique in endoscopic full-thickness resection for treating gastric subepithelial lesions
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作者 Meng Zhang Jiao Liu +9 位作者 Yun-Peng Dong Qian Zhao Mei-Ling Lin Teng-Jiao Gao Jia-Li Feng Yi-Fei Wang Yu-Fan Guo Zhen Wang Wen Jia Zhuo Yang 《World Journal of Gastrointestinal Surgery》 2025年第6期342-352,共11页
BACKGROUND Gastric subepithelial lesions(SELs)are elevated lesions originating from the muscularis mucosa,submucosa,or muscularis propria,and may also include extraluminal lesions.For small SELs(less than 5 cm),comple... BACKGROUND Gastric subepithelial lesions(SELs)are elevated lesions originating from the muscularis mucosa,submucosa,or muscularis propria,and may also include extraluminal lesions.For small SELs(less than 5 cm),complete endoscopic excision is the preferred treatment.Endoscopic full-thickness resection(EFTR)has proven to be an effective approach.AIM To evaluate the efficacy of the interrupted closure technique compared to the traditional closure technique in EFTR for gastric SELs.METHODS This single-center,prospective,randomized controlled trial was conducted at a tertiary hospital from September 2023 to September 2024.A total of 90 patients who underwent EFTR for gastric SELs were randomly allocated to either the interrupted closure group(n=44)or the traditional closure group(n=46).RESULTS All patients had complete resection and wound closure without any severe postoperative complications.The incidence of intraoperative gas-related complications was significantly lower in the interrupted closure group than in the traditional closure group(2.27%vs 26.09%,P=0.001),demonstrating interrupted closure technique can reduce the incidence of gas-related issues.Statistical analysis revealed that the incidence of postoperative infection was significantly lower in the experimental group than in the control group(15.91%vs 41.30%,P=0.008).Additionally,the median duration of antibiotic use was lower in the experimental group(3.5 days vs 5 days,P=0.013).Abdominal pain levels on postoperative days 1 and 4 were also lower in the experimental group compared to the control group(P<0.001).CONCLUSION The interrupted closure technique in EFTR for treating gastric SELs is safe and effective,reducing the incidence of intraoperative gas complications and postoperative infections. 展开更多
关键词 Endoscopic full-thickness resection interrupted closure Gastric subepithelial lesion Gas complication Postoperative infection
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Evaluating the impact of refined drug control on orthopedic medication use in the DRGs system:An interrupted time series analysis
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作者 Tiantian Xu Yingqiu Tu +3 位作者 Shengtao Zhang Jun Xiao Bin Zhang Fuchong Lai 《Journal of Chinese Pharmaceutical Sciences》 2025年第8期775-783,共9页
In the context of the Diagnosis Related Groups(DRGs)system,the orthopedic hospital implemented refined drug control to provide a pharmacological reference for promoting rational clinical drug use.A statistical analysi... In the context of the Diagnosis Related Groups(DRGs)system,the orthopedic hospital implemented refined drug control to provide a pharmacological reference for promoting rational clinical drug use.A statistical analysis was conducted on the hospital’s data from January to December 2021(prior to the implementation of control),focusing on the types of unreasonable prescriptions.A multi-dimensional analysis was also conducted to identify the underlying causes of inappropriate medication practices.Following this,refined drug control measures were introduced,and data from January to December 2022(post-control)were compared,examining factors such as the average drug cost,drug expenses for the IC29 diagnosis group,and the drug cost ratio.An interrupted time-series analysis was employed to evaluate the effects of these interventions.The results showed that after the implementation of refined drug control in the orthopedic department,significant reductions were observed in the average cost per patient,average drug cost per patient,drug cost ratio,cost consumption index,average length of hospital stay,and allocation ratio(P<0.05).In particular,the first month of control(January 2022)saw a marked decrease in average drug costs per patient by 1272.90 yuan(P<0.01),a reduction in the drug cost ratio by 0.98%,and a decline in drug costs for the IC29 diagnosis group by 616.79 yuan(P>0.05).Moreover,the rate of unreasonable inappropriate prescribing dropped dramatically from 40.48%in 2021 to 3.57%by December 2022.The refined control of drug use within the orthopedic hospital significantly improved the rationality of clinical prescribing practices,reduced the occurrence of adverse drug reactions,and enhanced patient adherence to prescribed treatments.These findings demonstrated considerable clinical value in promoting efficient and safe drug use. 展开更多
关键词 Refined control of drugs Average drug cost interrupted time series
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A method to address the challenges of charging conditions on incremental capacity analysis:An ICA-compensation technique incorporating current interrupt methods
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作者 Jinghua Sun Josef Kainz 《Journal of Energy Chemistry》 2025年第9期65-80,I0004,共17页
The incremental capacity analysis(ICA)technique is notably limited by its sensitivity to variations in charging conditions,which constrains its practical applicability in real-world scenarios.This paper introduces an ... The incremental capacity analysis(ICA)technique is notably limited by its sensitivity to variations in charging conditions,which constrains its practical applicability in real-world scenarios.This paper introduces an ICA-compensation technique to address this limitation and propose a generalized framework for assessing the state of health(SOH)of batteries based on ICA that is applicable under differing charging conditions.This novel approach calculates the voltage profile under quasi-static conditions by subtracting the voltage increase attributable to the additional polarization effects at high currents from the measured voltage profile.This approach's efficacy is contingent upon precisely acquiring the equivalent impedance.To obtain the equivalent impedance throughout the batteries'lifespan while minimizing testing costs,this study employs a current interrupt technique in conjunction with a long short-term memory(LSTM)network to develop a predictive model for equivalent impedance.Following the derivation of ICA curves using voltage profiles under quasi-static conditions,the research explores two scenarios for SOH estimation:one utilizing only incremental capacity(IC)features and the other incorporating both IC features and IC sampling.A genetic algorithm-optimized backpropagation neural network(GABPNN)is employed for the SOH estimation.The proposed generalized framework is validated using independent training and test datasets.Variable test conditions are applied for the test set to rigorously evaluate the methodology under challenging conditions.These evaluation results demonstrate that the proposed framework achieves an estimation accuracy of 1.04%for RMSE and 0.90%for MAPE across a spectrum of charging rates ranging from 0.1 C to 1 C and starting SOCs between 0%and 70%,which constitutes a major advancement compared to established ICA methods.It also significantly enhances the applicability of conventional ICA techniques in varying charging conditions and negates the necessity for separate testing protocols for each charging scenario. 展开更多
关键词 Lithium-ion batteries Incremental capacity analysis Charging conditions State of health Current interrupt method
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Nonperiodic interrupted sampling repeater jamming suppression for inverse synthetic aperture radar
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作者 WU Qihua ZHAO Feng +3 位作者 ZHAO Tiehua LIU Xiaobin XU Zhiming XIAO Shunping 《Journal of Systems Engineering and Electronics》 2025年第4期940-950,共11页
Nonperiodic interrupted sampling repeater jamming(ISRJ)against inverse synthetic aperture radar(ISAR)can obtain two-dimensional blanket jamming performance by joint fast and slow time domain interrupted modulation,whi... Nonperiodic interrupted sampling repeater jamming(ISRJ)against inverse synthetic aperture radar(ISAR)can obtain two-dimensional blanket jamming performance by joint fast and slow time domain interrupted modulation,which is obviously dif-ferent from the conventional multi-false-target deception jam-ming.In this paper,a suppression method against this kind of novel jamming is proposed based on inter-pulse energy function and compressed sensing theory.By utilizing the discontinuous property of the jamming in slow time domain,the unjammed pulse is separated using the intra-pulse energy function diffe-rence.Based on this,the two-dimensional orthogonal matching pursuit(2D-OMP)algorithm is proposed.Further,it is proposed to reconstruct the ISAR image with the obtained unjammed pulse sequence.The validity of the proposed method is demon-strated via the Yake-42 plane data simulations. 展开更多
关键词 jamming suppression compressed sensing(CS) interrupted sampling repeater jamming(ISRJ) energy function inverse synthetic aperture radar(ISAR).
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信息技术引致的工作中断研究回顾与展望
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作者 代宝 杨利英 郑怡晴 《心理技术与应用》 2026年第1期51-64,共14页
现代职场中,信息技术的广泛应用在提高员工间沟通协作效率的同时,也导致员工的工作更加容易发生中断。基于理论-情境-方法框架和前因-作用机制-结果框架对已有文献进行了系统剖析,厘清了信息技术引致的工作中断的理论基础、研究情境和... 现代职场中,信息技术的广泛应用在提高员工间沟通协作效率的同时,也导致员工的工作更加容易发生中断。基于理论-情境-方法框架和前因-作用机制-结果框架对已有文献进行了系统剖析,厘清了信息技术引致的工作中断的理论基础、研究情境和研究方法,总结了信息技术引致的工作中断的影响因素及后果,构建了信息技术引致的工作中断研究的整合框架,并指出未来研究可以拓展研究情境和改进研究方法,深入挖掘信息技术引致的工作中断的影响效应,开展跨行业和跨文化比较研究以及应对与管理研究。 展开更多
关键词 信息技术 工作中断 理论-情境-方法框架 前因-作用机制-结果框架
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Analyses of unified congestion measures for interrupted traffic flow on urban roads 被引量:1
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作者 任刚 范超 +2 位作者 华璟怡 黄正锋 吴建波 《Journal of Southeast University(English Edition)》 EI CAS 2014年第1期101-106,共6页
To study the congestion of interrupted flow on urban roads, a comprehensive evaluation method is proposed. First, based on the results of correlation analysis between different parameters of interrupted flow, the traf... To study the congestion of interrupted flow on urban roads, a comprehensive evaluation method is proposed. First, based on the results of correlation analysis between different parameters of interrupted flow, the traffic parameters of interrupted traffic flow are divided into two categories: the basic parameters and the operation parameters. Polynomial regression is used to formulize the nonlinear relationships between the basic parameters and the operation parameters. Then, the congestion model incorporating both operational and volume characteristics of traffic flow is proposed. The inputs of the model are the basic parameters, while the output is a dimensionless index value between 0 and 1. Finally, the proposed methods are compared with existing evaluation measures of congestion. Results show that the proposed indices can capture the variation of both the basic parameters and the operation parameters, which is more balanced compared with the existing evaluation measures. 展开更多
关键词 interrupted flow correlation analysis polynomial regression comprehensive congestion model
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基于中断时间序列分析宜昌市法定传染病流行趋势及防控效果
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作者 吴倩 张皓 +3 位作者 杨忠诚 周玲 梁艺 曹亚军 《公共卫生与预防医学》 2026年第1期88-92,共5页
目的分析2015—2023年宜昌市法定传染病流行特征,评估非药物干预措施(NPIs)对传染病防控效果,为制定防控策略提供依据。方法采用描述性流行病学方法分析年度发病率,构建SARIMA和SARIMA干预模型预测传染病发病率,结合中断时间序列分析(I... 目的分析2015—2023年宜昌市法定传染病流行特征,评估非药物干预措施(NPIs)对传染病防控效果,为制定防控策略提供依据。方法采用描述性流行病学方法分析年度发病率,构建SARIMA和SARIMA干预模型预测传染病发病率,结合中断时间序列分析(ITS)评估防控效果。结果2015—2023年年均发病率为787.47/10万,发病率居前五位的病种为流行性感冒(363.31/10万)、手足口病(103.77/10万)、乙肝(90.64/10万)、肺结核(76.52/10万)、其他感染性腹泻病(74.60/10万)。2015—2019年均发病率(654.31/10万)显著高于2020—2022年均发病率489.01/10万(X^(2)=3499.6,P<0.05);2023年总发病率为2396.51/10万显著高于2015—2019年(X^(2)=108186.1,P<0.05)和2020—2022年年均发病率(X^(2)=112869.4,P<0.05)。SARIMA模型显示,2020—2022年实际发病率较无干预情况下下降73.49%,其中呼吸道传染病下降率最高(79.57%)。SARIMA-干预模型显示,2023年总发病率下降55.48%,呼吸道传染病下降63.28%,肠道传染病下降-5.48%。结论NPIs短期内有效降低法定传染病发病率,特别对急性呼吸道和肠道传染病效果显著,但长期效果面临挑战,需制定差异化防控策略。 展开更多
关键词 法定传染病 SARIMA模型 中断时间序列 流行特征
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国家药品集中采购政策对口服降糖药的长期影响与替代效应研究——基于四川省实证数据
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作者 王静翠 谢佳利 +4 位作者 何昆 许凌巧 武志昂 唐晓蓉 胡明 《卫生经济研究》 北大核心 2026年第1期19-25,共7页
目的:分析国家组织药品集中采购政策对口服降糖药的长期影响和替代效应。方法:基于四川省公立医疗机构的口服降糖药采购数据,分析集中采购政策实施前后药品的量价关系。结果:集中采购政策实施后,口服降糖药均价下降2.24元(P<0.05),... 目的:分析国家组织药品集中采购政策对口服降糖药的长期影响和替代效应。方法:基于四川省公立医疗机构的口服降糖药采购数据,分析集中采购政策实施前后药品的量价关系。结果:集中采购政策实施后,口服降糖药均价下降2.24元(P<0.05),采购量持续上升,量价关系呈显著负相关(P<0.05);仿制药月均采购量占比从78.9%提升至86.5%,价格降幅显著高于原研药;中选品种采购量增幅超过50倍,价格下降,而非中选品种价格变化不明显;集采品种采购量显著增加,采购单价下降,但临床可替代品种的采购量持续上升,价格趋势无显著变化。结论:集中采购政策有效降低了药品价格、提升了药品可及性,并促进了仿制药替代,但对非中选及临床可替代品种的价格影响有限;未来政策应强化临床价值导向,通过精细化管理扩大政策覆盖范围,推动药品价格合理回归。 展开更多
关键词 药品集中采购 口服降糖药 替代效应 长期效应 间断时间序列分析
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Interrupt CW Approach for IF Video Signal Real Time Simulating and Its Validity
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作者 朱灿焰 龙腾 +1 位作者 何佩琨 毛二可 《Journal of Beijing Institute of Technology》 EI CAS 2000年第1期73-79,共7页
To determine the feasibility and practicability of interrupt continuous wave (CW) approach proposed for real time simulating radar intermediate frequency(IF) video signal, theoretical analysis and computer simulation... To determine the feasibility and practicability of interrupt continuous wave (CW) approach proposed for real time simulating radar intermediate frequency(IF) video signal, theoretical analysis and computer simulation were used. Phases at two linked points between the end and beginning of adjoined frames are always consistent; the bias Doppler frequency for the time delay of A/D sampling start responds to that for target acceleration. No digital phase compensation is required at continuous points, and the interrupt CW approach has apparently practical values. 展开更多
关键词 intermediate frequency(IF) video signal generating in low IF(LIF) domain interrupt continuous wave (CW) phase shift A/D sampling delay error
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Impacts of National Basic Medical Insurance Drug List adjustment on drug utilization in China: an interrupted time series study 被引量:4
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作者 翁庚 马莉莉 +2 位作者 刘伊 管晓东 史录文 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2015年第11期754-763,共10页
Under Chinese medicine and health care system, Medicine Catalogue for National Basic Medical Insurance(2009) was issued in 2009 in China to fulfill the basic drug demands of the insured Chinese and to control the me... Under Chinese medicine and health care system, Medicine Catalogue for National Basic Medical Insurance(2009) was issued in 2009 in China to fulfill the basic drug demands of the insured Chinese and to control the medical expenses. In this study, the influence of the list adjustment on drug utilization was investigated. With the comparison between inpatients' use of drugs before and after adjustment of Basic Medical Insurance Drug List, we classified the drugs adjusted in national list into six categories: class A to class B, class B to class A, class A to class C, class B to class C, class C to class A, and class C to class B(class A referring to overall insured drugs, class B referring to partial reimbursement drugs, class C referring to self-funded drugs in China), and drug utilization and expenditure were analyzed with time series model. We analyzed the overall expenditure and average expenditure per 10 000 people based on the comparison before and after the adjustment of 2009 Basic Medical Insurance Drug List. The drug expenditure from class A to class B was decreased by 13.87% of overall expenditure and 16.37% of average expenditure per 10 000 people, and it was decreased by 38.74% and 48.03% from class A to class C; respectively, the drug expenditure from class B to class A was increased by 74.12% and 94.52%, while it was reduced by 19.79% and 14.52% from class B to class C; expenditure declined by 31.77% and 36.22% from class C to class A, and expenditure was increased by 12.42% and 22.05% from class C to class B, respectively, both were lower than before. The adjustment of National Basic Medical Insurance Drug List reduced the overall drug expenditure. 展开更多
关键词 Medical insurance Drug list Drug utilization interrupted time series
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Role of the medullary reticular formation in motor control and functional recovery following spinal cord injury
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作者 Frederic Bretzner 《Neural Regeneration Research》 2026年第3期1138-1139,共2页
Spinal cord injury(SCI)interrupts the flow of information between the brain and the spinal cord,thus leading to a loss of sensory information and motor paralysis of the body below the lesion.Surprisingly,most SCIs are... Spinal cord injury(SCI)interrupts the flow of information between the brain and the spinal cord,thus leading to a loss of sensory information and motor paralysis of the body below the lesion.Surprisingly,most SCIs are incomplete and spare supraspinal pathways,especially those located within the peripheral white matter of the spinal cord,which includes reticulospinal pathways originating from the medullary reticular formation.Whereas there is abundant literature about the motor cortex,its corticospinal pathway,and its capacity to modulate functional recovery after SCI,less is known about the medullary reticular formation and its reticulospinal pathway. 展开更多
关键词 spinal cord injury sci interrupts supraspinal pathwaysespecially peripheral white matter motor cortexits spinal cordthus corticospinal pathway spinal cordwhich reticulospinal pathways
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ECCM scheme against interrupted sampling repeater jammer based on time-frequency analysis 被引量:41
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作者 Shixian Gong Xizhang Wei Xiang Li 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2014年第6期996-1003,共8页
The interrupted sampling repeater jamming(ISRJ) is an effective deception jamming method for coherent radar, especially for the wideband linear frequency modulation(LFM) radar. An electronic counter-countermeasure... The interrupted sampling repeater jamming(ISRJ) is an effective deception jamming method for coherent radar, especially for the wideband linear frequency modulation(LFM) radar. An electronic counter-countermeasure(ECCM) scheme is proposed to remove the ISRJ-based false targets from the pulse compression result of the de-chirping radar. Through the time-frequency(TF) analysis of the radar echo signal, it can be found that the TF characteristics of the ISRJ signal are discontinuous in the pulse duration because the ISRJ jammer needs short durations to receive the radar signal. Based on the discontinuous characteristics a particular band-pass filter can be generated by two alternative approaches to retain the true target signal and suppress the ISRJ signal. The simulation results prove the validity of the proposed ECCM scheme for the ISRJ. 展开更多
关键词 interrupted sampling repeater jamming(ISRJ) de-chirping radar time-frequency(TF) electronic counter-countermeasure(ECCM)
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Using Interrupted Time Series Design to Analyze Changes in Hand, Foot, and Mouth Disease Incidence during the Declining Incidence Periods of 2008-2010 in China 被引量:26
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作者 YU Shi Cheng HAO Yuan Tao +5 位作者 ZHANG Jing XIAO Ge Xin LIU Zhuang ZHU Qi MA Jia Qi WANG Yu 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2012年第6期645-652,共8页
Objective To identify patterns of hand, foot and mouth disease (HFMD) incidence in China during declining incidence periods of 2008, 2009, and 2010. Methods Reported HFMD cases over a period of 25 months were extrac... Objective To identify patterns of hand, foot and mouth disease (HFMD) incidence in China during declining incidence periods of 2008, 2009, and 2010. Methods Reported HFMD cases over a period of 25 months were extracted from the National Disease Reporting System (NDRS) and analyzed. An interrupted time series (ITS) technique was used to detect changes in HFMD incidence rates in terms of level and slope between declining incidence periods of the three years. Results Over 3.58 million HFMD cases younger than 5 years were reported to the NDRS between May 1, 2008, and May 31, 2011. Males comprised 63.4% of the cases. ITS analyses demonstrated a significant increase in incidence rate level (P〈0.0001) when comparing the current period with the previous period. There were significant changes in declining slopes when comparing 2010 to 2009, and 2010 to 2008 (all P〈O.O05), but not 2009 to 2008. Conclusion Incremental changes in incidence rate level during the declining incidence periods of 2009 and 2010 can potentially be attributed to a few factors. The more steeply declining slope in 2010 compared with previous years could be ascribed to the implementation of more effective interventions and preventive strategies in 2010. Further investigation is required to examine this possibility. 展开更多
关键词 Hand foot and mouth disease EPIDEMIC Infectious disease Disease surveillance interrupted time series analysis
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MEASUREMENT OF ANODIC OVERVOLTAGE BY AMODIFIED CURRENT INTERRUPTION METHOD IN CRYOLITE-ALUMINA MELTS 被引量:7
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作者 Yang, Jianhong Lai, Yanqing +3 位作者 Xiao, Jin Li, Jie Liu, Yexiang Thonstad, J. 《中国有色金属学会会刊:英文版》 EI CSCD 1999年第1期123-129,共7页
1INTRODUCTIONIntheelectrolyticproductionofaluminium,thecelconsistsofacarbonanodeandanaluminiummetalcathode.T... 1INTRODUCTIONIntheelectrolyticproductionofaluminium,thecelconsistsofacarbonanodeandanaluminiummetalcathode.Thedominantpotent... 展开更多
关键词 anodic OVERVOLTAGE CURRENT interruptION METHOD aluminium electrolysis
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A new car-following model with consideration of the traffic interruption probability 被引量:5
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作者 唐铁桥 黄海军 +1 位作者 黄仕进 姜锐 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第3期975-983,共9页
In this paper, we present a new car-following model by taking into account the effects of the traffic interruption probability on the car-following behaviour of the following vehicle. The stability condition of the mo... In this paper, we present a new car-following model by taking into account the effects of the traffic interruption probability on the car-following behaviour of the following vehicle. The stability condition of the model is obtained by using the linear stability theory. The modified Korteweg-de Vries (KdV) equation is constructed and solved, and three types of traffic flows in the headway sensitivity space-stable, metastable, and unstable--are classified. Both the analytical and simulation results show that the traffic interruption probability indeed has an influence on driving behaviour, and the consideration of traffic interruption probability in the car-following model could stabilize traffic flow. 展开更多
关键词 car-following model traffic interruption probability STABILITY
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A randomized controlled clinical trial: Interruption of intrauterine transmission of hepatitis B virus infection with HBIG 被引量:26
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作者 Qin XH Lin Xi-ao +2 位作者 Xiao-Bo Lu Yue-Xin Zhang Xia Cai 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第21期3434-3437,共4页
AIM: To evaluate the efficacy of interruption of intrauterine infection of HBV with HBIG in pregnant women with positive HBeAg and HBsAg.METHODS: A prospective randomized controlled trial was adopted. Sixty cases wi... AIM: To evaluate the efficacy of interruption of intrauterine infection of HBV with HBIG in pregnant women with positive HBeAg and HBsAg.METHODS: A prospective randomized controlled trial was adopted. Sixty cases with positive HBeAg and HBsAg were coincident with the criteria of inclusion, and 8 cases were excluded. Fifty-two cases were analyzed (28 cases in trial group and 24 in control group). All cases in trial group received 200 IU HBIG intravenously every 4 wk for 3 times from the 28^th wk. The cases of control group received placebo in the same way. All pregnant women were detected for HBeAg and HBV-DNA at the beginning of the trial and end of the trial (delivery). The cord blood of all newborns were collected for detecting HBeAg and HBV-DNA simultaneously.RESULTS: For investigation of HBeAg of newborns in trial group, 6 of 28 cases of newborns had positive HBeAg, the HBeAg positive rate being 21.4%, the total rate of 95% CI being 8%-41%. In control group, 19 of 24 cases of newborns had positive HBeAg, HBeAg positive rate was 79.2%, the rate of 95%CI being 5%-93%. By statistical analysis, 2= 17.26, P 〈 0.01, RR = 0.27, 95% CI (6.3 × 10^-6, 8.6 × 10^-5). For investigation of HBV-DNA of newborns in trial group, 7 of 28 cases of newborns had positive HBV-DNA, HBV-DNA positive rate being 25%, the total rate of 95% CI being 11%-45%. In control group, 20 of 24 cases of newborns had positive HBV-DNA, HBV-DNA positive rate was 83.3%, the total rate of 95% CI being 63%-95%. By statistical analysis, X^2 = 17.62, P 〈 0.01, RR = 0.30, 95% CI (1.5 × 10^-5, 1.7× 10^-4). The results indicated that there was significant difference in HBeAg positive rate and HBV-DNA positive rate of newborns between the two groups. In trial group, 7 of 28 newborns had HBV-DNA positive, but the HBV-DNA load of newborns was lower than that of their mothers. In control group, 20 of 24 newborns still had HBV-DNA positive, and the HBV-DNA load of newborns was close to those of their mothers. Statistical analysis indicated that there was no significant difference in HBV- DNA load between postnatal women without HBIG intervention and their filial generations (T = 81.5, P 〉 0.1). CONCLUSION: It is effective and safe to prevent intrauterine infection of HBV with HBIG from the 28^th wk in pregnant women with positive HBeAg and HBsAg. In clinical application, those pregnant women with negative HBeAg and positive HBV-DNA also need to be interrupted by HBIG. 展开更多
关键词 interruptION INTRAUTERINE TRANSMISSION Hepatitis B virus HBIG
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Knowledge, attitude and practice regarding nursing interruptions among Chinese nurses: A nationwide cross-sectional survey 被引量:10
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作者 Jianfei Xie Qian Sun +6 位作者 Siyuan Tang Siqing Ding Zhuqing Zhong Sainan Zeng Yinglong Duan Xiangyan Zhang Andy SK.Cheng 《International Journal of Nursing Sciences》 CSCD 2020年第1期66-73,共8页
Objectives:To explore the knowledge,attitude and practice of Chinese nurses regarding nursing interruptions and related factors.Methods:A total of 6,400 nurses from 31 hospitals in China were investigated by using the... Objectives:To explore the knowledge,attitude and practice of Chinese nurses regarding nursing interruptions and related factors.Methods:A total of 6,400 nurses from 31 hospitals in China were investigated by using the Knowledge,Attitude and Practice(KAP)Questionnaire of Nursing Interruptions.The questionnaire consists of three dimensions,knowledge,attitude and practice,containing 10,9 and 7 items,with full score of 50,45 and 28,respectively.Results:The mean overall KAP score regarding nursing interruptions of Chinese nurses was 74.05±16.65(range:26-123),with scores for the knowledge,attitude,and practice component being 21.74±9.80,34.83±6.98,and 17.49±4.97,respectively.Among the nurses,70.8%of them experienced an average level of KAP toward nursing interruptions while 15.5%were at a poor level.The knowledge,attitude,and practice of nursing interruptions were better in chief nurses,managers,nurses with a master degree or above,nurses ever received training,and nurses with a strong agreement to leadership compared to nurses in other groups(P<0.05).In addition,employment type,professional title,position,standardized training and leaders'attention were predictors of KAP in nurses.Conclusion:Chinese nurses have a moderate level of KAP regarding nursing interruptions.Leaders'attention,standardized training,position,professional title and employment type could predict nurses'KAP state of nursing interruptions.Thus,a targeted training program should be implemented for clinical nurses by nursing leaders,with a particular focus on feasibility and professionalism. 展开更多
关键词 ATTITUDE KNOWLEDGE NURSING NURSING interruptIONS PRACTICE Questionnaires
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Abnormal interruption of water flow from an artesian well prior to 2008 Wenchuan earthquake 被引量:5
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作者 Liu Chenglong Che Yongtai +2 位作者 Xu Yinju Shi Zheming Yang Xianhe 《Geodesy and Geodynamics》 2011年第2期53-57,共5页
Water flow from an artesian well stopped on December 17, 2007 but recovered when the Wenchuan Ms 8.0 earthquake occurred on May 12, 2008. This well is located 90 km south of the epicenter in an extensional tectonic se... Water flow from an artesian well stopped on December 17, 2007 but recovered when the Wenchuan Ms 8.0 earthquake occurred on May 12, 2008. This well is located 90 km south of the epicenter in an extensional tectonic setting, where similar changes of water level and resistivity were observed at two other nearby sites. Our investigation suggests that this phenomenon was not caused by environmental disturbances, such as drought or borehole-drilling activity, but might be a precursor to the earthquake. 展开更多
关键词 interruption of well water precursory anomaly Wenchuan earthquake Qionglai well
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