Thermally induced apoptosis for tumors depends mainly on the intrinsic characteristics of biological tissues as well as treatment temperature profile during magnetic hyperthermia.Further,treatment temperature distribu...Thermally induced apoptosis for tumors depends mainly on the intrinsic characteristics of biological tissues as well as treatment temperature profile during magnetic hyperthermia.Further,treatment temperature distribution inside tumor depends on the injection behavior of irregular tumors,such as the injection dose and the injection location of nanofluids.In order to improve the treatment effect,the simulated annealing algorithm is adopted in this work to optimize the nanofluid injection behavior,and the improved Arrhenius model is used to evaluate the malignant ablations for three typical malignant tumor cell models.In addition,both the injection behavior optimization and the mass diffusion of nanofluid are both taken into consideration in order to improve the treatment effect.The simulation results demonstrate that the injection behavior can be optimized effectively by the proposed optimization method before therapy,the result of which can also conduce to improving the thermal apoptosis possibility for proposed typical malignant cells.Furthermore,an effective approach is also employed by considering longer diffusion duration and correct power dissipation at the same time.The results show that a better result can then be obtained than those in other cases when the power dissipation of MNPs is set to be QMNP=5.4×10^(7)W·m^(3) and the diffusion time is 16 h.展开更多
In this paper, we observe experimentally the optical bistability induced by the side-mode injection power and wave- length detuning in a single mode Fabry-P6rot laser diode （SMFP-LD）. Results show that the bistabili...In this paper, we observe experimentally the optical bistability induced by the side-mode injection power and wave- length detuning in a single mode Fabry-P6rot laser diode （SMFP-LD）. Results show that the bistability characteristics of the dominant and injected modes are strongly dependent on the injected input optical power and wavelength detuning in an SMFP-LD. We observe three types of hysteresis loops： counterclockwise, clockwise, and butterfly hysteresis with various loop widths. In the case of a bistability loop caused by injection power, the transition from counterclockwise to clockwise in the hysteresis direction with the wavelength detuning from 0.028 nm to 0.112 nm is observed in a way of butterfly hys- teresis for the dominant mode by increasing the wavelength detuning. The width of hysteresis loop, induced by wavelength detuning is also changed while the injection power is enhanced from -7 dBm to -5 dBm.展开更多
基金Project supported by the National Natural Science Foundation of China (Grant No. 62071124)the Natural Science Foundation of Fujian Province, China (Grant No. 2020J01464)+2 种基金the Fund from the Education Department of Fujian Province, China (Grant No. JAT190013)the Fund from the Fuzhou University, China (Grant No. GXRC-19044)the Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR) (CNPq) (Grant No. 309244/2018-8)
文摘Thermally induced apoptosis for tumors depends mainly on the intrinsic characteristics of biological tissues as well as treatment temperature profile during magnetic hyperthermia.Further,treatment temperature distribution inside tumor depends on the injection behavior of irregular tumors,such as the injection dose and the injection location of nanofluids.In order to improve the treatment effect,the simulated annealing algorithm is adopted in this work to optimize the nanofluid injection behavior,and the improved Arrhenius model is used to evaluate the malignant ablations for three typical malignant tumor cell models.In addition,both the injection behavior optimization and the mass diffusion of nanofluid are both taken into consideration in order to improve the treatment effect.The simulation results demonstrate that the injection behavior can be optimized effectively by the proposed optimization method before therapy,the result of which can also conduce to improving the thermal apoptosis possibility for proposed typical malignant cells.Furthermore,an effective approach is also employed by considering longer diffusion duration and correct power dissipation at the same time.The results show that a better result can then be obtained than those in other cases when the power dissipation of MNPs is set to be QMNP=5.4×10^(7)W·m^(3) and the diffusion time is 16 h.
基金supported by the National Natural Science Foundation of China(Grant No.61205111)the Open Foundation of State Key Laboratory of Millimeter Waves,China(Grant No.K201219)the Natural Science Foundation of Chongqing Normal University,China(Grant No.2011XLZ06)
文摘In this paper, we observe experimentally the optical bistability induced by the side-mode injection power and wave- length detuning in a single mode Fabry-P6rot laser diode （SMFP-LD）. Results show that the bistability characteristics of the dominant and injected modes are strongly dependent on the injected input optical power and wavelength detuning in an SMFP-LD. We observe three types of hysteresis loops： counterclockwise, clockwise, and butterfly hysteresis with various loop widths. In the case of a bistability loop caused by injection power, the transition from counterclockwise to clockwise in the hysteresis direction with the wavelength detuning from 0.028 nm to 0.112 nm is observed in a way of butterfly hys- teresis for the dominant mode by increasing the wavelength detuning. The width of hysteresis loop, induced by wavelength detuning is also changed while the injection power is enhanced from -7 dBm to -5 dBm.
