Wireless avionics intra-communications(WAIC)is an emergent research topic,since it can improve fuel efficiency and enhance aircraft safety significantly.However,there are numerous baffles in an aircraft,e.g.,seats and...Wireless avionics intra-communications(WAIC)is an emergent research topic,since it can improve fuel efficiency and enhance aircraft safety significantly.However,there are numerous baffles in an aircraft,e.g.,seats and cabin bulkheads,resulting in serious blockage and even destroying wireless communications.Thus,this paper focuses on the reconfigurable intelligent surface(RIS)deployment issue of RIS-assisted WAIC systems,to solve the blockage problem caused by baffles.We first propose the mirror-symmetric imaging principle for mathematically analyzing electromagnetic(EM)wave propagation in a metal cuboid,which is a typical structure of WAIC systems.Based on the mirror-symmetric imaging principle,the mathematical channel model in a metal cuboid is deduced in detail.In addition,we develop an objective function of RIS's location and deduce the optimal RIS deployment location based on the geometric center optimization lemma.A two-dimensional gravity center search algorithm is then presented.Simulation results show that the designed RIS deployment can greatly increase the received power and efficiently solve the blockage problem in the aircraft.展开更多
The quantity of space debris on Earth orbit has escalated tremendously in recent years, presenting a significant hazard to human space operations. It is urgent to develop effective measures to capture and remove vario...The quantity of space debris on Earth orbit has escalated tremendously in recent years, presenting a significant hazard to human space operations. It is urgent to develop effective measures to capture and remove various space debris. For this purpose, this paper presents a tendon-actuated flexible deployable manipulator. The flexible manipulator consists of several deployable units connected by Cardan joints and actuated by tendons. Compared with the present technologies for capturing space debris such as rigid robotic arm or flying net, this flexible manipulator is deployable, reusable, lightweight and applicable to the capture of large space debris. In order to investigate its deployment dynamics, an accurate dynamic model of the flexible manipulator is established based on the natural coordinate formulation (NCF) and the absolute nodal coordinate formulation (ANCF). Subsequently, numerical simulations are carried out to study the effects of system parameters and the base satellite on its deployment dynamics. Finally, ground experiments for both deployment and bending of the flexible manipulator are conducted to verify its effectiveness and feasibility.展开更多
The spacecraft with multistage solar panels have nonlinear coupling between attitudes of central body and solar panels, especially the rotation of central body is considered in space. The dynamics model is based for d...The spacecraft with multistage solar panels have nonlinear coupling between attitudes of central body and solar panels, especially the rotation of central body is considered in space. The dynamics model is based for dynamics analysis and control, and the multistage solar panels means the dynamics modeling will be very complex. In this research, the Lie group variational integrator method is introduced, and the dynamics model of spacecraft with solar panels that connects together by flexible joints is built. The most obvious character of this method is that the attitudes of central body and solar panels are all described by three-dimensional attitude matrix. The dynamics models of spacecraft with one and three solar panels are established and simulated. The study shows Lie group variational integrator method avoids parameters coupling and effectively reduces difficulty of modeling. The obtained continuous dynamics model based on Lie group is a set of ordinary differential equations and equivalent with traditional dynamics model that offers a basis for the geometry control.展开更多
Recently,Internet of Drones(IoD)has garnered significant attention due to its widespread applications.However,deploying IoD for area coverage poses numerous limitations and challenges.These include interference betwee...Recently,Internet of Drones(IoD)has garnered significant attention due to its widespread applications.However,deploying IoD for area coverage poses numerous limitations and challenges.These include interference between neighboring drones,the need for directional antennas,and altitude restrictions for drones.These challenges necessitate the development of efficient solutions.This research paper presents a cooperative decision-making approach for an efficient IoDdeployment to address these challenges effectively.The primary objective of this study is to achieve an efficient IoDdeployment strategy thatmaximizes the coverage regionwhile minimizing interference between neighboring drones.In deployment problem,the interference increases as the number of deployed drones increases,resulting in bad quality of communication.On the other hand,deploying a few drones cannot satisfy the coverage demand.To accomplish this,an enhanced version of a concise population-based meta-heuristic algorithm,namely Improved Particle SwarmOptimization(IPSO),is applied.The objective function of IPSO is defined based on the coverage probability,which is primarily influenced by the characteristics of the antennas and drone altitude.A radio frequency(RF)model is derived to evaluate the coverage quality,considering both Line of Sight(LOS)and Non-Line of Sight(NLOS)down-link coverage probabilities for ground communication.It is assumed that each drone is equipped with a directional antenna to optimize coverage in a given region.Extensive simulations are conducted to assess the effectiveness of the proposed approach.Results demonstrate that the proposed method achieves maximum coverage with minimum transmission power.Furthermore,a comparison is made against Collaborative Visual Area Coverage Approach(CVACA),and a game-based approach in terms of coverage quality and convergence speed.The simulation results reveal that our approach outperforms both CVACA and the gamebased schemes in terms of coverage and convergence speed.Comparisons validate the superiority of our approach over existing methods.To assess the robustness of the proposed RFmodel,we have considered two distinct ranges of noise:range1 spanning from−120 to−90 dBm,and range2 spanning from−90 to−70 dBmfor different numbers of UAVs.In summary,this research presents a cooperative decision-making approach for efficient IoD deployment to address the challenges associatedwith area coverage and achieves an optimal coveragewithminimal interference.展开更多
As a large amount of data is increasingly generated from edge devices,such as smart homes,mobile phones,and wearable devices,it becomes crucial for many applications to deploy machine learning modes across edge device...As a large amount of data is increasingly generated from edge devices,such as smart homes,mobile phones,and wearable devices,it becomes crucial for many applications to deploy machine learning modes across edge devices.The execution speed of the deployed model is a key element to ensure service quality.Considering a highly heterogeneous edge deployment scenario,deep learning compiling is a novel approach that aims to solve this problem.It defines models using certain DSLs and generates efficient code implementations on different hardware devices.However,there are still two aspects that are not yet thoroughly investigated yet.The first is the optimization of memory-intensive operations,and the second problem is the heterogeneity of the deployment target.To that end,in this work,we propose a system solution that optimizes memory-intensive operation,optimizes the subgraph distribution,and enables the compiling and deployment of DNN models on multiple targets.The evaluation results show the performance of our proposed system.展开更多
Workow management technologies have been dramatically improving their deployment architectures and systems along with the evolution and proliferation of cloud distributed computing environments.Especially,such cloud c...Workow management technologies have been dramatically improving their deployment architectures and systems along with the evolution and proliferation of cloud distributed computing environments.Especially,such cloud computing environments ought to be providing a suitable distributed computing paradigm to deploy very large-scale workow processes and applications with scalable on-demand services.In this paper,we focus on the distribution paradigm and its deployment formalism for such very large-scale workow applications being deployed and enacted across the multiple and heterogeneous cloud computing environments.We propose a formal approach to vertically as well as horizontally fragment very large-scale workow processes and their applications and to deploy the workow process and application fragments over three types of cloud deployment models and architectures.To concretize the formal approach,we rstly devise a series of operational situations fragmenting into cloud workow process and application components and deploying onto three different types of cloud deployment models and architectures.These concrete approaches are called the deployment-driven fragmentation mechanism to be applied to such very large-scale workow process and applications as an implementing component for cloud workow management systems.Finally,we strongly believe that our approach with the fragmentation formalisms becomes a theoretical basis of designing and implementing very large-scale and maximally distributed workow processes and applications to be deployed on cloud deployment models and architectural computing environments as well.展开更多
Energy supply is one of the most critical challenges of wireless sensor networks(WSNs)and industrial wireless sensor networks(IWSNs).While research on coverage optimization problem(COP)centers on the network’s monito...Energy supply is one of the most critical challenges of wireless sensor networks(WSNs)and industrial wireless sensor networks(IWSNs).While research on coverage optimization problem(COP)centers on the network’s monitoring coverage,this research focuses on the power banks’energy supply coverage.The study of 2-D and 3-D spaces is typical in IWSN,with the realistic environment being more complex with obstacles(i.e.,machines).A 3-D surface is the field of interest(FOI)in this work with the established hybrid power bank deployment model for the energy supply COP optimization of IWSN.The hybrid power bank deployment model is highly adaptive and flexible for new or existing plants already using the IWSN system.The model improves the power supply to a more considerable extent with the least number of power bank deployments.The main innovation in this work is the utilization of a more practical surface model with obstacles and training while improving the convergence speed and quality of the heuristic algorithm.An overall probabilistic coverage rate analysis of every point on the FOI is provided,not limiting the scope to target points or areas.Bresenham’s algorithm is extended from 2-D to 3-D surface to enhance the probabilistic covering model for coverage measurement.A dynamic search strategy(DSS)is proposed to modify the artificial bee colony(ABC)and balance the exploration and exploitation ability for better convergence toward eliminating NP-hard deployment problems.Further,the cellular automata(CA)is utilized to enhance the convergence speed.The case study based on two typical FOI in the IWSN shows that the CA scheme effectively speeds up the optimization process.Comparative experiments are conducted on four benchmark functions to validate the effectiveness of the proposed method.The experimental results show that the proposed algorithm outperforms the ABC and gbest-guided ABC(GABC)algorithms.The results show that the proposed energy coverage optimization method based on the hybrid power bank deployment model generates more accurate results than the results obtained by similar algorithms(i.e.,ABC,GABC).The proposed model is,therefore,effective and efficient for optimization in the IWSN.展开更多
Modeling and attitude control methods for a satellite with a large deployable antenna are studied in the present paper. Firstly, for reducing the model dimension, three dynamic models for the deploying process are dev...Modeling and attitude control methods for a satellite with a large deployable antenna are studied in the present paper. Firstly, for reducing the model dimension, three dynamic models for the deploying process are developed, which are built with the methods of multi-rigid-body dynam- ics, hybrid coordinate and substructure. Then an attitude control method suitable for the deploying process is proposed, which can keep stability under any dynamical parameter variation. Subse- quently, this attitude control is optimized to minimize attitude disturbance during the deploying process. The simulation results show that this attitude control method can keep stability and main- tain proper attitude variation during the deploying process, which indicates that this attitude con- trol method is suitable for practical applications.展开更多
The tether deployment of a tethered satellite system involves the consideration of complex dynamic properties of the tether,such as large deformation,slack,and even rebound,and therefore,the dynamic modelling of the t...The tether deployment of a tethered satellite system involves the consideration of complex dynamic properties of the tether,such as large deformation,slack,and even rebound,and therefore,the dynamic modelling of the tether is necessary for performing a dynamic analysis of the system.For a variablelength tether element,the absolute nodal coordinate formulation(ANCF)in the framework of the arbitrary Lagrange-Euler(ALE)description was used to develop a precise dynamic model of a tethered satellite.The model considered the gravitational gradient force and Coriolis force in the orbital coordinate frame,and it was validated through numerical simulation.In the presence of dynamic constraints,a deployment velocity of the tether was obtained by an optimal procedure.In the simulation,rebound behavior of the tethered satellite system was observed when the ANCF-ALE model was employed.Notably,the rebound behavior cannot be predicted by the traditional dumbbell model.Furthermore,an improved optimal deployment velocity was developed.Simulation results indicated that the rebound phenomenon was eliminated,and smooth deployment as well as a stable state of the station-keeping process were achieved.Additionally,the swing amplitude in the station-keeping phase decreased when a deployment strategy based on the improved optimal deployment velocity was used.展开更多
BACKGROUND Neck pain,a primary symptom of cervical spondylosis,affects patients'physical and mental health,reducing their quality of life.Pain and emotional state interact;however,their longitudinal interrelations...BACKGROUND Neck pain,a primary symptom of cervical spondylosis,affects patients'physical and mental health,reducing their quality of life.Pain and emotional state interact;however,their longitudinal interrelationship remains unclear.In this study,we applied a dual-trajectory model to assess how neck pain and emotional state evolve together over time and how clinical interventions,particularly acupuncture,influence these trajectories.AIM To investigate the longitudinal relationship between neck pain and emotional state in patients with cervical spondylosis.METHODS This prospective cohort study included 472 patients with cervical spondylosis from eight Chinese hospitals.Participants received acupuncture or medication and were followed up at baseline,and at 1,2,4,6,and 8 weeks.Neck pain and emotional distress were assessed using the Northwick Park Neck Pain Questionnaire(NPQ)and the affective subscale of the Short-Form McGill Pain Questionnaire(SF-MPQ),respectively.Group-based trajectory models and dual trajectory analysis were used to identify and correlate pain-emotion trajectories.Multivariate logistic regression identified predictors of group membership.RESULTS Three trajectory groups were identified for NPQ and SF-MPQ scores(low,medium,and high).Higher NPQ trajectory was associated with older age(OR=1.058,P<0.001)and was significantly reduced by acupuncture(OR=0.382,P<0.001).Similarly,acupuncture lowered the odds of high SF-MPQ trajectory membership(OR=0.336,P<0.001),while age increased it(OR=1.037,P<0.001).Dual-trajectory analysis revealed bidirectional associations:69.1%of patients with low NPQ had low SF-MPQ scores,and 42.6%of patients with high SF-MPQ also had high NPQ scores.Gender was a predictor for medium SF-MPQ trajectory(OR=1.629,P=0.094).Occupation and education levels differed significantly across the trajectory groups(P<0.05).CONCLUSION Over time,neck pain and emotional distress are closely associated in patients with cervical spondylosis.Acupuncture alleviates both outcomes significantly,while age is a risk factor.Integrated approaches to pain and emotional management are encouraged.展开更多
Objective:Sepsis exhibits remarkable heterogeneity in disease progression trajectories,and accurate identificationof distinct trajectory-based phenotypes is critical for implementing personalized therapeutic strategie...Objective:Sepsis exhibits remarkable heterogeneity in disease progression trajectories,and accurate identificationof distinct trajectory-based phenotypes is critical for implementing personalized therapeutic strategies and prognostic assessment.However,trajectory clustering analysis of time-series clinical data poses substantial methodological challenges for researchers.This study provides a comprehensive tutorial framework demonstrating six trajectory modeling approaches integrated with proteomic analysis to guide researchers in identifying sepsis subtypes after laparoscopic surgery.Methods:This study employs simulated longitudinal data from 300 septic patients after laparoscopic surgery to demonstrate six trajectory modeling methods(group-based trajectory modeling,latent growth mixture modeling,latent transition analysis,time-varying effect modeling,K-means for longitudinal data,agglomerative hierarchical clustering)for identifying associations between predefinedsequential organ failure assessment trajectories and 25 proteomic biomarkers.Clustering performance was evaluated via multiple metrics,and a biomarker discovery pipeline integrating principal component analysis,random forests,feature selection,and receiver operating characteristic analysis was developed.Results:The six methods demonstrated varying performance in identifying trajectory structures,with each approach exhibiting distinct analytical characteristics.The performance metrics revealed differences across methods,which may inform context-specificmethod selection and interpretation strategies.Conclusion:This study illustrates practical implementations of trajectory modeling approaches under controlled conditions,facilitating informed method selection for clinical researchers.The inclusion of complete R code and integrated proteomics workflows offers a reproducible analytical framework connecting temporal pattern recognition to biomarker discovery.Beyond sepsis,this pipeline-oriented approach may be adapted to diverse clinical scenarios requiring longitudinal disease characterization and precision medicine applications.The comparative analysis reveals that each method has distinct strengths,providing a practical guide for clinical researchers in selecting appropriate methods based on their specificstudy goals and data characteristics.展开更多
Most predictive maintenance studies have emphasized accuracy but provide very little focus on Interpretability or deployment readiness.This study improves on prior methods by developing a small yet robust system that ...Most predictive maintenance studies have emphasized accuracy but provide very little focus on Interpretability or deployment readiness.This study improves on prior methods by developing a small yet robust system that can predict when turbofan engines will fail.It uses the NASA CMAPSS dataset,which has over 200,000 engine cycles from260 engines.The process begins with systematic preprocessing,which includes imputation,outlier removal,scaling,and labelling of the remaining useful life.Dimensionality is reduced using a hybrid selection method that combines variance filtering,recursive elimination,and gradient-boosted importance scores,yielding a stable set of 10 informative sensors.To mitigate class imbalance,minority cases are oversampled,and class-weighted losses are applied during training.Benchmarking is carried out with logistic regression,gradient boosting,and a recurrent design that integrates gated recurrent units with long short-term memory networks.The Long Short-Term Memory–Gated Recurrent Unit(LSTM–GRU)hybrid achieved the strongest performance with an F1 score of 0.92,precision of 0.93,recall of 0.91,ReceiverOperating Characteristic–AreaUnder the Curve(ROC-AUC)of 0.97,andminority recall of 0.75.Interpretability testing using permutation importance and Shapley values indicates that sensors 13,15,and 11 are the most important indicators of engine wear.The proposed system combines imbalance handling,feature reduction,and Interpretability into a practical design suitable for real industrial settings.展开更多
The growing recognition of the role of genetics in the development of amyotrophic lateral sclerosis is evident.However,there has yet to be a comprehensive analysis of the clinical characteristics and genetics of famil...The growing recognition of the role of genetics in the development of amyotrophic lateral sclerosis is evident.However,there has yet to be a comprehensive analysis of the clinical characteristics and genetics of familial amyotrophic lateral sclerosis in an Asian population.This study aimed to provide an in-depth analysis of the clinical features and genetic spectrum of familial amyotrophic lateral sclerosis over 15 years in a clinic-based cohort of patients from the Chinese mainland.Enrollment of 302 amyotrophic lateral sclerosis families from 28 provinces was undertaken from January 2008 to September 2023.A group-based trajectory model for disease progression based on amyotrophic lateral sclerosis Functional Rating Scale-Revised(ALSFRS-R)scores was validated using bootstrap internal validation in patients with familial amyotrophic lateral sclerosis,as well as patients with sporadic amyotrophic lateral sclerosis(matched at a 1:4 ratio,with replacement).DNA samples from 244 index patients were screened for variants in the pathogenic genes SOD1,FUS,TDP43,and C9ORF72,of which 146 were also subjected to genome-wide next-generation sequencing.Gene-level burden analysis was used to evaluate the distribution of rare variants in the cohort.We found that rapid dynamic disease progression was associated with an older age at onset,shorter diagnostic delay,lower body mass index,bulbar onset,and≥1 affected first-degree relative.Certain attributes,such as age at onset and time from onset to diagnosis,had comparable impacts on the clinical progression trajectories of both familial amyotrophic lateral sclerosis and sporadic amyotrophic lateral sclerosis.Harboring pathogenic/likely pathogenic variants in amyotrophic lateral sclerosis-causative genes reduced the age of onset of familial amyotrophic lateral sclerosis.Among the patients with familial amyotrophic lateral sclerosis,17.8%possessed≥2 pathogenic/likely pathogenic variants.Sequencing kernel association test analysis showed that the SOD1 rare variant burden(P=1.3e-15)was associated with a significant risk of familial amyotrophic lateral sclerosis.Our findings conclusively confirmed the clinical features and genetic spectrum of familial amyotrophic lateral sclerosis over 15 years in a clinical cohort from China,contributing to a deeper understanding of genotype-phenotype relationships in familial amyotrophic lateral sclerosis.This comprehensive evaluation of specific clinical characteristics,clinical prognosis,and genetic variants of amyotrophic lateral sclerosis based on detailed clinical and genetic information may lead to the development of genotype-specific treatment approaches.展开更多
基金supported by the National Natural Science Foundation of China under Grand No.62071148 and No.62171151partly by the Natural Science Foundation of Heilongjiang Province of China under Grand No.YQ2019F009partly by the Fundamental Research Funds for Central Universities under Grand No.HIT.OCEF.2021012。
文摘Wireless avionics intra-communications(WAIC)is an emergent research topic,since it can improve fuel efficiency and enhance aircraft safety significantly.However,there are numerous baffles in an aircraft,e.g.,seats and cabin bulkheads,resulting in serious blockage and even destroying wireless communications.Thus,this paper focuses on the reconfigurable intelligent surface(RIS)deployment issue of RIS-assisted WAIC systems,to solve the blockage problem caused by baffles.We first propose the mirror-symmetric imaging principle for mathematically analyzing electromagnetic(EM)wave propagation in a metal cuboid,which is a typical structure of WAIC systems.Based on the mirror-symmetric imaging principle,the mathematical channel model in a metal cuboid is deduced in detail.In addition,we develop an objective function of RIS's location and deduce the optimal RIS deployment location based on the geometric center optimization lemma.A two-dimensional gravity center search algorithm is then presented.Simulation results show that the designed RIS deployment can greatly increase the received power and efficiently solve the blockage problem in the aircraft.
基金the National Natural Science Foundation of China(Nos.11832005,12372042,12232011)Young Elite Scientists Sponsorship Program by CAST(No.2022QNRC001)+1 种基金the Fundamental Research Funds for the Central Universities(No.NS2023002)State Key Laboratory of Mechanics and Control for Aerospace Structures(Nanjing University of Aeronautics and Astronautics)(No.MCAS-S-0223K04).
文摘The quantity of space debris on Earth orbit has escalated tremendously in recent years, presenting a significant hazard to human space operations. It is urgent to develop effective measures to capture and remove various space debris. For this purpose, this paper presents a tendon-actuated flexible deployable manipulator. The flexible manipulator consists of several deployable units connected by Cardan joints and actuated by tendons. Compared with the present technologies for capturing space debris such as rigid robotic arm or flying net, this flexible manipulator is deployable, reusable, lightweight and applicable to the capture of large space debris. In order to investigate its deployment dynamics, an accurate dynamic model of the flexible manipulator is established based on the natural coordinate formulation (NCF) and the absolute nodal coordinate formulation (ANCF). Subsequently, numerical simulations are carried out to study the effects of system parameters and the base satellite on its deployment dynamics. Finally, ground experiments for both deployment and bending of the flexible manipulator are conducted to verify its effectiveness and feasibility.
基金the financial support from the National Natural Science Foundation of China (Grants 11732005 and 11472058)
文摘The spacecraft with multistage solar panels have nonlinear coupling between attitudes of central body and solar panels, especially the rotation of central body is considered in space. The dynamics model is based for dynamics analysis and control, and the multistage solar panels means the dynamics modeling will be very complex. In this research, the Lie group variational integrator method is introduced, and the dynamics model of spacecraft with solar panels that connects together by flexible joints is built. The most obvious character of this method is that the attitudes of central body and solar panels are all described by three-dimensional attitude matrix. The dynamics models of spacecraft with one and three solar panels are established and simulated. The study shows Lie group variational integrator method avoids parameters coupling and effectively reduces difficulty of modeling. The obtained continuous dynamics model based on Lie group is a set of ordinary differential equations and equivalent with traditional dynamics model that offers a basis for the geometry control.
基金funded by Project Number INML2104 under the Interdisciplinary Center of Smart Mobility and Logistics at King Fahd University of Petroleum and Minerals.This study also was supported by the Special Research Fund BOF23KV17.
文摘Recently,Internet of Drones(IoD)has garnered significant attention due to its widespread applications.However,deploying IoD for area coverage poses numerous limitations and challenges.These include interference between neighboring drones,the need for directional antennas,and altitude restrictions for drones.These challenges necessitate the development of efficient solutions.This research paper presents a cooperative decision-making approach for an efficient IoDdeployment to address these challenges effectively.The primary objective of this study is to achieve an efficient IoDdeployment strategy thatmaximizes the coverage regionwhile minimizing interference between neighboring drones.In deployment problem,the interference increases as the number of deployed drones increases,resulting in bad quality of communication.On the other hand,deploying a few drones cannot satisfy the coverage demand.To accomplish this,an enhanced version of a concise population-based meta-heuristic algorithm,namely Improved Particle SwarmOptimization(IPSO),is applied.The objective function of IPSO is defined based on the coverage probability,which is primarily influenced by the characteristics of the antennas and drone altitude.A radio frequency(RF)model is derived to evaluate the coverage quality,considering both Line of Sight(LOS)and Non-Line of Sight(NLOS)down-link coverage probabilities for ground communication.It is assumed that each drone is equipped with a directional antenna to optimize coverage in a given region.Extensive simulations are conducted to assess the effectiveness of the proposed approach.Results demonstrate that the proposed method achieves maximum coverage with minimum transmission power.Furthermore,a comparison is made against Collaborative Visual Area Coverage Approach(CVACA),and a game-based approach in terms of coverage quality and convergence speed.The simulation results reveal that our approach outperforms both CVACA and the gamebased schemes in terms of coverage and convergence speed.Comparisons validate the superiority of our approach over existing methods.To assess the robustness of the proposed RFmodel,we have considered two distinct ranges of noise:range1 spanning from−120 to−90 dBm,and range2 spanning from−90 to−70 dBmfor different numbers of UAVs.In summary,this research presents a cooperative decision-making approach for efficient IoD deployment to address the challenges associatedwith area coverage and achieves an optimal coveragewithminimal interference.
基金supported by the National Natural Science Foundation of China(U21A20519)。
文摘As a large amount of data is increasingly generated from edge devices,such as smart homes,mobile phones,and wearable devices,it becomes crucial for many applications to deploy machine learning modes across edge devices.The execution speed of the deployed model is a key element to ensure service quality.Considering a highly heterogeneous edge deployment scenario,deep learning compiling is a novel approach that aims to solve this problem.It defines models using certain DSLs and generates efficient code implementations on different hardware devices.However,there are still two aspects that are not yet thoroughly investigated yet.The first is the optimization of memory-intensive operations,and the second problem is the heterogeneity of the deployment target.To that end,in this work,we propose a system solution that optimizes memory-intensive operation,optimizes the subgraph distribution,and enables the compiling and deployment of DNN models on multiple targets.The evaluation results show the performance of our proposed system.
基金supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(Grant Number 2020R1A6A1A03040583)。
文摘Workow management technologies have been dramatically improving their deployment architectures and systems along with the evolution and proliferation of cloud distributed computing environments.Especially,such cloud computing environments ought to be providing a suitable distributed computing paradigm to deploy very large-scale workow processes and applications with scalable on-demand services.In this paper,we focus on the distribution paradigm and its deployment formalism for such very large-scale workow applications being deployed and enacted across the multiple and heterogeneous cloud computing environments.We propose a formal approach to vertically as well as horizontally fragment very large-scale workow processes and their applications and to deploy the workow process and application fragments over three types of cloud deployment models and architectures.To concretize the formal approach,we rstly devise a series of operational situations fragmenting into cloud workow process and application components and deploying onto three different types of cloud deployment models and architectures.These concrete approaches are called the deployment-driven fragmentation mechanism to be applied to such very large-scale workow process and applications as an implementing component for cloud workow management systems.Finally,we strongly believe that our approach with the fragmentation formalisms becomes a theoretical basis of designing and implementing very large-scale and maximally distributed workow processes and applications to be deployed on cloud deployment models and architectural computing environments as well.
文摘Energy supply is one of the most critical challenges of wireless sensor networks(WSNs)and industrial wireless sensor networks(IWSNs).While research on coverage optimization problem(COP)centers on the network’s monitoring coverage,this research focuses on the power banks’energy supply coverage.The study of 2-D and 3-D spaces is typical in IWSN,with the realistic environment being more complex with obstacles(i.e.,machines).A 3-D surface is the field of interest(FOI)in this work with the established hybrid power bank deployment model for the energy supply COP optimization of IWSN.The hybrid power bank deployment model is highly adaptive and flexible for new or existing plants already using the IWSN system.The model improves the power supply to a more considerable extent with the least number of power bank deployments.The main innovation in this work is the utilization of a more practical surface model with obstacles and training while improving the convergence speed and quality of the heuristic algorithm.An overall probabilistic coverage rate analysis of every point on the FOI is provided,not limiting the scope to target points or areas.Bresenham’s algorithm is extended from 2-D to 3-D surface to enhance the probabilistic covering model for coverage measurement.A dynamic search strategy(DSS)is proposed to modify the artificial bee colony(ABC)and balance the exploration and exploitation ability for better convergence toward eliminating NP-hard deployment problems.Further,the cellular automata(CA)is utilized to enhance the convergence speed.The case study based on two typical FOI in the IWSN shows that the CA scheme effectively speeds up the optimization process.Comparative experiments are conducted on four benchmark functions to validate the effectiveness of the proposed method.The experimental results show that the proposed algorithm outperforms the ABC and gbest-guided ABC(GABC)algorithms.The results show that the proposed energy coverage optimization method based on the hybrid power bank deployment model generates more accurate results than the results obtained by similar algorithms(i.e.,ABC,GABC).The proposed model is,therefore,effective and efficient for optimization in the IWSN.
基金sponsored by the National Natural Science Foundation of China (No. 11272172)
文摘Modeling and attitude control methods for a satellite with a large deployable antenna are studied in the present paper. Firstly, for reducing the model dimension, three dynamic models for the deploying process are developed, which are built with the methods of multi-rigid-body dynam- ics, hybrid coordinate and substructure. Then an attitude control method suitable for the deploying process is proposed, which can keep stability under any dynamical parameter variation. Subse- quently, this attitude control is optimized to minimize attitude disturbance during the deploying process. The simulation results show that this attitude control method can keep stability and main- tain proper attitude variation during the deploying process, which indicates that this attitude con- trol method is suitable for practical applications.
基金supported by the Natural Science Foundation of Shaanxi Province,China(2020JQ-288)Science and Technology on Space Intelligent Control Laboratory,China(HTKJ2019KL502016)+1 种基金China Scholarship Council(201806120093)National Natural Science Foundation of China(61903289).
文摘The tether deployment of a tethered satellite system involves the consideration of complex dynamic properties of the tether,such as large deformation,slack,and even rebound,and therefore,the dynamic modelling of the tether is necessary for performing a dynamic analysis of the system.For a variablelength tether element,the absolute nodal coordinate formulation(ANCF)in the framework of the arbitrary Lagrange-Euler(ALE)description was used to develop a precise dynamic model of a tethered satellite.The model considered the gravitational gradient force and Coriolis force in the orbital coordinate frame,and it was validated through numerical simulation.In the presence of dynamic constraints,a deployment velocity of the tether was obtained by an optimal procedure.In the simulation,rebound behavior of the tethered satellite system was observed when the ANCF-ALE model was employed.Notably,the rebound behavior cannot be predicted by the traditional dumbbell model.Furthermore,an improved optimal deployment velocity was developed.Simulation results indicated that the rebound phenomenon was eliminated,and smooth deployment as well as a stable state of the station-keeping process were achieved.Additionally,the swing amplitude in the station-keeping phase decreased when a deployment strategy based on the improved optimal deployment velocity was used.
基金Supported by 2022 Chinese Medicine Scientific Research Project of Hebei Administration of Traditional Chinese Medicine,No.20221572025 Annual Scientific Research Project of Higher Education Institutions in Hebei Province,No.QN2025654.
文摘BACKGROUND Neck pain,a primary symptom of cervical spondylosis,affects patients'physical and mental health,reducing their quality of life.Pain and emotional state interact;however,their longitudinal interrelationship remains unclear.In this study,we applied a dual-trajectory model to assess how neck pain and emotional state evolve together over time and how clinical interventions,particularly acupuncture,influence these trajectories.AIM To investigate the longitudinal relationship between neck pain and emotional state in patients with cervical spondylosis.METHODS This prospective cohort study included 472 patients with cervical spondylosis from eight Chinese hospitals.Participants received acupuncture or medication and were followed up at baseline,and at 1,2,4,6,and 8 weeks.Neck pain and emotional distress were assessed using the Northwick Park Neck Pain Questionnaire(NPQ)and the affective subscale of the Short-Form McGill Pain Questionnaire(SF-MPQ),respectively.Group-based trajectory models and dual trajectory analysis were used to identify and correlate pain-emotion trajectories.Multivariate logistic regression identified predictors of group membership.RESULTS Three trajectory groups were identified for NPQ and SF-MPQ scores(low,medium,and high).Higher NPQ trajectory was associated with older age(OR=1.058,P<0.001)and was significantly reduced by acupuncture(OR=0.382,P<0.001).Similarly,acupuncture lowered the odds of high SF-MPQ trajectory membership(OR=0.336,P<0.001),while age increased it(OR=1.037,P<0.001).Dual-trajectory analysis revealed bidirectional associations:69.1%of patients with low NPQ had low SF-MPQ scores,and 42.6%of patients with high SF-MPQ also had high NPQ scores.Gender was a predictor for medium SF-MPQ trajectory(OR=1.629,P=0.094).Occupation and education levels differed significantly across the trajectory groups(P<0.05).CONCLUSION Over time,neck pain and emotional distress are closely associated in patients with cervical spondylosis.Acupuncture alleviates both outcomes significantly,while age is a risk factor.Integrated approaches to pain and emotional management are encouraged.
基金funding from the China National Key Research and Development Program(No.2023YFC3603104)the National Natural Science Foundation of China(Nos.82472243 and 82272180)+6 种基金the Fundamental Research Funds for the Central Universities(No.226-2025-00024)the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.LHDMD24H150001)the Key Research&Development Project of Zhejiang Province(No.2024C03240)a collaborative scientific project co-established by the Science and Technology Department of the National Administration of Traditional Chinese Medicine and the Zhejiang Provincial Administration of Traditional Chinese Medicine(No.GZY-ZJ-KJ-24082)he General Health Science and Technology Program of Zhejiang Province(No.2024KY1099)the Project of Zhejiang University Longquan Innovation Center(No.ZJDXLQCXZCJBGS2024016)Wu Jieping Medical Foundation Special Research Grant(No.320.6750.2024-23-07).
文摘Objective:Sepsis exhibits remarkable heterogeneity in disease progression trajectories,and accurate identificationof distinct trajectory-based phenotypes is critical for implementing personalized therapeutic strategies and prognostic assessment.However,trajectory clustering analysis of time-series clinical data poses substantial methodological challenges for researchers.This study provides a comprehensive tutorial framework demonstrating six trajectory modeling approaches integrated with proteomic analysis to guide researchers in identifying sepsis subtypes after laparoscopic surgery.Methods:This study employs simulated longitudinal data from 300 septic patients after laparoscopic surgery to demonstrate six trajectory modeling methods(group-based trajectory modeling,latent growth mixture modeling,latent transition analysis,time-varying effect modeling,K-means for longitudinal data,agglomerative hierarchical clustering)for identifying associations between predefinedsequential organ failure assessment trajectories and 25 proteomic biomarkers.Clustering performance was evaluated via multiple metrics,and a biomarker discovery pipeline integrating principal component analysis,random forests,feature selection,and receiver operating characteristic analysis was developed.Results:The six methods demonstrated varying performance in identifying trajectory structures,with each approach exhibiting distinct analytical characteristics.The performance metrics revealed differences across methods,which may inform context-specificmethod selection and interpretation strategies.Conclusion:This study illustrates practical implementations of trajectory modeling approaches under controlled conditions,facilitating informed method selection for clinical researchers.The inclusion of complete R code and integrated proteomics workflows offers a reproducible analytical framework connecting temporal pattern recognition to biomarker discovery.Beyond sepsis,this pipeline-oriented approach may be adapted to diverse clinical scenarios requiring longitudinal disease characterization and precision medicine applications.The comparative analysis reveals that each method has distinct strengths,providing a practical guide for clinical researchers in selecting appropriate methods based on their specificstudy goals and data characteristics.
基金supported by the Deanship of Scientific Research,Vice Presidency for Graduate Studies and Scientific Research,King Faisal University,Saudi Arabia Grant No.KFU253765.
文摘Most predictive maintenance studies have emphasized accuracy but provide very little focus on Interpretability or deployment readiness.This study improves on prior methods by developing a small yet robust system that can predict when turbofan engines will fail.It uses the NASA CMAPSS dataset,which has over 200,000 engine cycles from260 engines.The process begins with systematic preprocessing,which includes imputation,outlier removal,scaling,and labelling of the remaining useful life.Dimensionality is reduced using a hybrid selection method that combines variance filtering,recursive elimination,and gradient-boosted importance scores,yielding a stable set of 10 informative sensors.To mitigate class imbalance,minority cases are oversampled,and class-weighted losses are applied during training.Benchmarking is carried out with logistic regression,gradient boosting,and a recurrent design that integrates gated recurrent units with long short-term memory networks.The Long Short-Term Memory–Gated Recurrent Unit(LSTM–GRU)hybrid achieved the strongest performance with an F1 score of 0.92,precision of 0.93,recall of 0.91,ReceiverOperating Characteristic–AreaUnder the Curve(ROC-AUC)of 0.97,andminority recall of 0.75.Interpretability testing using permutation importance and Shapley values indicates that sensors 13,15,and 11 are the most important indicators of engine wear.The proposed system combines imbalance handling,feature reduction,and Interpretability into a practical design suitable for real industrial settings.
基金supported by the Natural Science Foundation of Beijing,Nos.7244428(to WZ)and 7222215(to JH)the Peking University Medicine Sailing Program forYoung Scholars’Scientific and Technological Innovation,No.BMU2023YFJHPY034(to WZ)+4 种基金the National Natural Science Foundation of China,Nos.81873784,82071426(to DF),and81974197(to JH)the Clinical Cohort Construction Program of Peking University Third Hospital,No.BYSYDL2019002(to DF)Beijing Physician-Scientist TrainingProgram,No.BJPSTP-2024-03(to JH)the China Postdoctoral Science Foundation,Nos.2022TQ0014(to LX),2022M720284(to LX)the E-Town Cooperation&Development Foundation,No.YCXJ-JZ-2023-017(to LX).
文摘The growing recognition of the role of genetics in the development of amyotrophic lateral sclerosis is evident.However,there has yet to be a comprehensive analysis of the clinical characteristics and genetics of familial amyotrophic lateral sclerosis in an Asian population.This study aimed to provide an in-depth analysis of the clinical features and genetic spectrum of familial amyotrophic lateral sclerosis over 15 years in a clinic-based cohort of patients from the Chinese mainland.Enrollment of 302 amyotrophic lateral sclerosis families from 28 provinces was undertaken from January 2008 to September 2023.A group-based trajectory model for disease progression based on amyotrophic lateral sclerosis Functional Rating Scale-Revised(ALSFRS-R)scores was validated using bootstrap internal validation in patients with familial amyotrophic lateral sclerosis,as well as patients with sporadic amyotrophic lateral sclerosis(matched at a 1:4 ratio,with replacement).DNA samples from 244 index patients were screened for variants in the pathogenic genes SOD1,FUS,TDP43,and C9ORF72,of which 146 were also subjected to genome-wide next-generation sequencing.Gene-level burden analysis was used to evaluate the distribution of rare variants in the cohort.We found that rapid dynamic disease progression was associated with an older age at onset,shorter diagnostic delay,lower body mass index,bulbar onset,and≥1 affected first-degree relative.Certain attributes,such as age at onset and time from onset to diagnosis,had comparable impacts on the clinical progression trajectories of both familial amyotrophic lateral sclerosis and sporadic amyotrophic lateral sclerosis.Harboring pathogenic/likely pathogenic variants in amyotrophic lateral sclerosis-causative genes reduced the age of onset of familial amyotrophic lateral sclerosis.Among the patients with familial amyotrophic lateral sclerosis,17.8%possessed≥2 pathogenic/likely pathogenic variants.Sequencing kernel association test analysis showed that the SOD1 rare variant burden(P=1.3e-15)was associated with a significant risk of familial amyotrophic lateral sclerosis.Our findings conclusively confirmed the clinical features and genetic spectrum of familial amyotrophic lateral sclerosis over 15 years in a clinical cohort from China,contributing to a deeper understanding of genotype-phenotype relationships in familial amyotrophic lateral sclerosis.This comprehensive evaluation of specific clinical characteristics,clinical prognosis,and genetic variants of amyotrophic lateral sclerosis based on detailed clinical and genetic information may lead to the development of genotype-specific treatment approaches.
