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Probabilistic Graphical Model-Based Operational Reliability-Centric Design of Offshore Wind Farm Feeder Layouts
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作者 Qiuyu Lu Yunqi Yan +4 位作者 Yang Liu Ying Chen Yinguo Yang Tannan Xiao Guobing Wu 《Energy Engineering》 2025年第12期4799-4814,共16页
The rapid expansion of offshore wind energy necessitates robust and cost-effective electrical collector system(ECS)designs that prioritize lifetime operational reliability.Traditional optimization approaches often sim... The rapid expansion of offshore wind energy necessitates robust and cost-effective electrical collector system(ECS)designs that prioritize lifetime operational reliability.Traditional optimization approaches often simplify reliability considerations or fail to holistically integrate them with economic and technical constraints.This paper introduces a novel,two-stage optimization framework for offshore wind farm(OWF)ECS planning that systematically incorporates reliability.The first stage employs Mixed-Integer Linear Programming(MILP)to determine an optimal radial network topology,considering linearized reliability approximations and geographical constraints.The second stage enhances this design by strategically placing tie-lines using a Mixed-Integer Quadratically Constrained Program(MIQCP).This stage leverages a dynamic-aware adaptation of Multi-Source Multi-Terminal Network Reliability(MSMT-NR)assessment,with its inherent nonlinear equations successfully transformed into a solvable MIQCP form for loopy networks.A benchmark case study demonstrates the framework’s efficacy,illustrating how increasing the emphasis on reliability leads to more distributed and interconnected network topologies,effectively balancing investment costs against enhanced system resilience. 展开更多
关键词 Offshore wind farm feeder layout optimization network reliability nonlinear optimization probabilistic graphical model
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Modeling and Integration Method of Sys ML Model for Complex Business Scenarios 被引量:1
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作者 Yu Bing An Baoran Zhao Shicao 《系统仿真学报》 CAS CSCD 北大核心 2024年第12期2797-2812,共16页
The development process of complex equipment involves multi-stage business processes,multi-level product architecture,and multi-disciplinary physical processes.The relationship between its system model and various dis... The development process of complex equipment involves multi-stage business processes,multi-level product architecture,and multi-disciplinary physical processes.The relationship between its system model and various disciplinary models is extremely complicated.In the modeling and integration process,extensive customized development is needed to realize model integration and interoperability in different business scenarios.Meanwhile,the differences in modeling and interaction between different modeling tools make it difficult to support the consistent representation of models in complex scenarios.To improve the efficiency of system modeling and integration in complex business scenarios,a system modeling and integration method was proposed.This method took the Sys ML language kernel as the core and system model function integration as the main line.Through the technical means of model view separation,abstract operation interface,and model view configuration,the model modeling and integration of multi-user,multi-model,multi-view,and different business logic in complex business scenarios were realized. 展开更多
关键词 SYSML model-based system engineering(MBSE) SERVICE graphical modeling V-business
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A graphical model for haloanhydrite components and P-wave velocity:A case study of haloanhydrites in Amu Darya Basin 被引量:2
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作者 Guo Tong-Cui Wang Hong-Jun +4 位作者 Mu Long-Xin Zhang Xing-Yang Ma Zhi Tian Yu Li Hao-Chen 《Applied Geophysics》 SCIE CSCD 2016年第3期459-468,579,共11页
Wave velocities in haloanhydrites are difficult to determine and significantly depend on the mineralogy. We used petrophysical parameters to study the wave velocity in haloanhydrites in the Amur Darya Basin and constr... Wave velocities in haloanhydrites are difficult to determine and significantly depend on the mineralogy. We used petrophysical parameters to study the wave velocity in haloanhydrites in the Amur Darya Basin and constructed a template of the relation between haloanhydrite mineralogy (anhydrite, salt, mudstone, and pore water) and wave velocities. We used the relation between the P-wave rnoduli ratio and porosity as constraint and constructed a graphical model (petrophysical template) for the relation between wave velocity, mineral content and porosity. We tested the graphical model using rock core and well logging data. 展开更多
关键词 SALT ANHYDRITE graphical model P-wave velocity Ainu Darya Basin
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A Modeling and Probabilistic Reasoning Method of Dynamic Uncertain Causality Graph for Industrial Fault Diagnosis 被引量:1
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作者 Chun-Ling Dong Qin Zhang Shi-Chao Geng 《International Journal of Automation and computing》 EI CSCD 2014年第3期288-298,共11页
Online automatic fault diagnosis in industrial systems is essential for guaranteeing safe, reliable and efficient operations.However, difficulties associated with computational overload, ubiquitous uncertainties and i... Online automatic fault diagnosis in industrial systems is essential for guaranteeing safe, reliable and efficient operations.However, difficulties associated with computational overload, ubiquitous uncertainties and insufficient fault samples hamper the engineering application of intelligent fault diagnosis technology. Geared towards the settlement of these problems, this paper introduces the method of dynamic uncertain causality graph, which is a new attempt to model complex behaviors of real-world systems under uncertainties. The visual representation to causality pathways and self-relied "chaining" inference mechanisms are analyzed. In particular, some solutions are investigated for the diagnostic reasoning algorithm to aim at reducing its computational complexity and improving the robustness to potential losses and imprecisions in observations. To evaluate the effectiveness and performance of this method, experiments are conducted using both synthetic calculation cases and generator faults of a nuclear power plant. The results manifest the high diagnostic accuracy and efficiency, suggesting its practical significance in large-scale industrial applications. 展开更多
关键词 Fault diagnosis causality model probabilistic graphical model uncertain knowledge representation weighted logic inference.
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Graphical model construction based on evolutionary algorithms
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作者 Youlong YANG Yan WU Sanyang LIU 《控制理论与应用(英文版)》 EI 2006年第4期349-354,共6页
Using Bayesian networks to model promising solutions from the current population of the evolutionary algorithms can ensure efficiency and intelligence search for the optimum. However, to construct a Bayesian network t... Using Bayesian networks to model promising solutions from the current population of the evolutionary algorithms can ensure efficiency and intelligence search for the optimum. However, to construct a Bayesian network that fits a given dataset is a NP-hard problem, and it also needs consuming mass computational resources. This paper develops a methodology for constructing a graphical model based on Bayesian Dirichlet metric. Our approach is derived from a set of propositions and theorems by researching the local metric relationship of networks matching dataset. This paper presents the algorithm to construct a tree model from a set of potential solutions using above approach. This method is important not only for evolutionary algorithms based on graphical models, but also for machine learning and data mining. The experimental results show that the exact theoretical results and the approximations match very well. 展开更多
关键词 graphical model Evolutionary algorithms Bayesian network Tree models Bayesian Dirichlet metric
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VIDEO MULTI-TARGET TRACKING BASED ON PROBABILISTIC GRAPHICAL MODEL
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作者 Xu Feng Huang Chenrong +1 位作者 Wu Zhengjun Xu Lizhong 《Journal of Electronics(China)》 2011年第4期548-557,共10页
In the technique of video multi-target tracking,the common particle filter can not deal well with uncertain relations among multiple targets.To solve this problem,many researchers use data association method to reduce... In the technique of video multi-target tracking,the common particle filter can not deal well with uncertain relations among multiple targets.To solve this problem,many researchers use data association method to reduce the multi-target uncertainty.However,the traditional data association method is difficult to track accurately when the target is occluded.To remove the occlusion in the video,combined with the theory of data association,this paper adopts the probabilistic graphical model for multi-target modeling and analysis of the targets relationship in the particle filter framework.Ex-perimental results show that the proposed algorithm can solve the occlusion problem better compared with the traditional algorithm. 展开更多
关键词 Video tracking Multi-target tracking Data association Probabilistic graphical model Particle filter
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Systemic Risk of Conventional and Islamic Banks: Comparison with Graphical Network Models
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作者 Shatha Qamhieh Hashem Paolo Giudici 《Applied Mathematics》 2016年第17期2079-2096,共19页
The main aim of this paper is to compare the stability, in terms of systemic risk, of conventional and Islamic banking systems. To this aim, we propose correlation network models for stock market returns based on grap... The main aim of this paper is to compare the stability, in terms of systemic risk, of conventional and Islamic banking systems. To this aim, we propose correlation network models for stock market returns based on graphical Gaussian distributions, which allows us to capture the contagion effects that move along countries. We also consider Bayesian graphical models, to account for model uncertainty in the measurement of financial systems interconnectedness. Our proposed model is applied to the Middle East and North Africa (MENA) region banking sector, characterized by the presence of both conventional and Islamic banks, for the period from 2007 to the beginning of 2014. Our empirical findings show that there are differences in the systemic risk and stability of the two banking systems during crisis times. In addition, the differences are subject to country specific effects that are amplified during crisis period. 展开更多
关键词 Financial Stability Centrality Measures graphical Gaussian Models Islamic Banks Conventional Banks Systemic Risk
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Predictive factors and model validation of post-colon polyp surgery Helicobacter pylori infection 被引量:4
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作者 Zheng-Sen Zhang 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第1期173-185,共13页
BACKGROUND Recently,research has linked Helicobacter pylori(H.pylori)stomach infection to colonic inflammation,mediated by toxin production,potentially impacting colorectal cancer occurrence.AIM To investigate the ris... BACKGROUND Recently,research has linked Helicobacter pylori(H.pylori)stomach infection to colonic inflammation,mediated by toxin production,potentially impacting colorectal cancer occurrence.AIM To investigate the risk factors for post-colon polyp surgery,H.pylori infection,and its correlation with pathologic type.METHODS Eighty patients who underwent colon polypectomy in our hospital between January 2019 and January 2023 were retrospectively chosen.They were then randomly split into modeling(n=56)and model validation(n=24)sets using R.The modeling cohort was divided into an H.pylori-infected group(n=37)and an H.pylori-uninfected group(n=19).Binary logistic regression analysis was used to analyze the factors influencing the occurrence of H.pylori infection after colon polyp surgery.A roadmap prediction model was established and validated.Finally,the correlation between the different pathological types of colon polyps and the occurrence of H.pylori infection was analyzed after colon polyp surgery.RESULTS Univariate results showed that age,body mass index(BMI),literacy,alcohol consumption,polyp pathology type,high-risk adenomas,and heavy diet were all influential factors in the development of H.pylori infection after intestinal polypectomy.Binary multifactorial logistic regression analysis showed that age,BMI,and type of polyp pathology were independent predictors of the occurrence of H.pylori infection after intestinal polypectomy.The area under the receiver operating characteristic curve was 0.969[95%confidence interval(95%CI):0.928–1.000]and 0.898(95%CI:0.773–1.000)in the modeling and validation sets,respectively.The slope of the calibration curve of the graph was close to 1,and the goodness-of-fit test was P>0.05 in the two sets.The decision analysis curve showed a high rate of return in both sets.The results of the correlation analysis between different pathological types and the occurrence of H.pylori infection after colon polyp surgery showed that hyperplastic polyps,inflammatory polyps,and the occurrence of H.pylori infection were not significantly correlated.In contrast,adenomatous polyps showed a significant positive correlation with the occurrence of H.pylori infection.CONCLUSION Age,BMI,and polyps of the adenomatous type were independent predictors of H.pylori infection after intestinal polypectomy.Moreover,the further constructed column-line graph prediction model of H.pylori infection after intestinal polypectomy showed good predictive ability. 展开更多
关键词 Colon polyps Helicobacter pylori Risk factors Pathologic type Columnar graphic modeling
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Reproducible Learning of Gaussian Graphical Models via Graphical Lasso Multiple Data Splitting
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作者 Kang Hu Danning Li Binghui Liu 《Acta Mathematica Sinica,English Series》 2025年第2期553-568,共16页
Gaussian graphical models(GGMs) are widely used as intuitive and efficient tools for data analysis in several application domains. To address the reproducibility issue of structure learning of a GGM, it is essential t... Gaussian graphical models(GGMs) are widely used as intuitive and efficient tools for data analysis in several application domains. To address the reproducibility issue of structure learning of a GGM, it is essential to control the false discovery rate(FDR) of the estimated edge set of the graph in terms of the graphical model. Hence, in recent years, the problem of GGM estimation with FDR control is receiving more and more attention. In this paper, we propose a new GGM estimation method by implementing multiple data splitting. Instead of using the node-by-node regressions to estimate each row of the precision matrix, we suggest directly estimating the entire precision matrix using the graphical Lasso in the multiple data splitting, and our calculation speed is p times faster than the previous. We show that the proposed method can asymptotically control FDR, and the proposed method has significant advantages in computational efficiency. Finally, we demonstrate the usefulness of the proposed method through a real data analysis. 展开更多
关键词 False discovery rate Gaussian graphical model multiple data splitting graphical Lasso
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Loopy belief propagation based data association for extended target tracking 被引量:4
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作者 Zhenzhen SU Hongbing JI Yongquan ZHANG 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2020年第8期2212-2223,共12页
The data association problem of multiple extended target tracking is very challenging because each target may generate multiple measurements.Recently,the belief propagation based multiple target tracking algorithms wi... The data association problem of multiple extended target tracking is very challenging because each target may generate multiple measurements.Recently,the belief propagation based multiple target tracking algorithms with high efficiency have been a research focus.Different from the belief propagation based Extended Target tracking based on Belief Propagation(ET-BP)algorithm proposed in our previous work,a new graphical model formulation of data association for multiple extended target tracking is proposed in this paper.The proposed formulation can be solved by the Loopy Belief Propagation(LBP)algorithm.Furthermore,the simplified measurement set in the ET-BP algorithm is modified to improve tracking accuracy.Finally,experiment results show that the proposed algorithm has better performance than the ET-BP and joint probabilistic data association based on the simplified measurement set algorithms in terms of accuracy and efficiency.Additionally,the convergence of the proposed algorithm is verified in the simulations. 展开更多
关键词 Belief propagation Data association Extended target graphical model Simplified measurement set Target tracking
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Toward the Next Generation of Retinal Neuroprosthesis: Visual Computation with Spikes 被引量:3
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作者 Zhaofei Yu Jian K.Liu +4 位作者 Shanshan Jia Yichen Zhang Yajing Zheng Yonghong Tian Tiejun Huang 《Engineering》 SCIE EI 2020年第4期449-461,共13页
A neuroprosthesis is a type of precision medical device that is intended to manipulate the neuronal signals of the brain in a closed-loop fashion,while simultaneously receiving stimuli from the environment and control... A neuroprosthesis is a type of precision medical device that is intended to manipulate the neuronal signals of the brain in a closed-loop fashion,while simultaneously receiving stimuli from the environment and controlling some part of a human brain or body.Incoming visual information can be processed by the brain in millisecond intervals.The retina computes visual scenes and sends its output to the cortex in the form of neuronal spikes for further computation.Thus,the neuronal signal of interest for a retinal neuroprosthesis is the neuronal spike.Closed-loop computation in a neuroprosthesis includes two stages:encoding a stimulus as a neuronal signal,and decoding it back into a stimulus.In this paper,we review some of the recent progress that has been achieved in visual computation models that use spikes to analyze natural scenes that include static images and dynamic videos.We hypothesize that in order to obtain a better understanding of the computational principles in the retina,a hypercircuit view of the retina is necessary,in which the different functional network motifs that have been revealed in the cortex neuronal network are taken into consideration when interacting with the retina.The different building blocks of the retina,which include a diversity of cell types and synaptic connections-both chemical synapses and electrical synapses(gap junctions)-make the retina an ideal neuronal network for adapting the computational techniques that have been developed in artificial intelligence to model the encoding and decoding of visual scenes.An overall systems approach to visual computation with neuronal spikes is necessary in order to advance the next generation of retinal neuroprosthesis as an artificial visual system. 展开更多
关键词 Visual coding RETINA NEUROPROSTHESIS Brain-machine interface Artificial intelligence Deep learning Spiking neural network Probabilistic graphical model
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Development of a building information model-guided post-earthquake building inspection framework using 3D synthetic environments 被引量:3
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作者 Nathaniel M.Levine Yasutaka Narazaki Billie F.Spencer 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2023年第2期279-307,共29页
Computer vision-based inspection methods show promise for automating post-earthquake building inspections.These methods survey a building with unmanned aerial vehicles and automatically detect damage in the collected ... Computer vision-based inspection methods show promise for automating post-earthquake building inspections.These methods survey a building with unmanned aerial vehicles and automatically detect damage in the collected images.Nevertheless,assessing the damage′s impact on structural safety requires localizing damage to specific building components with known design and function.This paper proposes a BIM-based automated inspection framework to provide context for visual surveys.A deep learning-based semantic segmentation algorithm is trained to automatically identify damage in images.The BIM automatically associates any identified damage with specific building components.Then,components are classified into damage states consistent with component fragility models for integration with a structural analysis.To demonstrate the framework,methods are developed to photorealistically simulate severe structural damage in a synthetic computer graphics environment.A graphics model of a real building in Urbana,Illinois,is generated to test the framework;the model is integrated with a structural analysis to apply earthquake damage in a physically realistic manner.A simulated UAV survey is flown of the graphics model and the framework is applied.The method achieves high accuracy in assigning damage states to visible structural components.This assignment enables integration with a performance-based earthquake assessment to classify building safety. 展开更多
关键词 computer vision earthquake engineering building information model physics-based graphics model synthetic environment
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BURST-LDA: A NEW TOPIC MODEL FOR DETECTING BURSTY TOPICS FROM STREAM TEXT 被引量:3
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作者 Qi Xiang Huang Yu +4 位作者 Chen Ziyan Liu Xiaoyan Tian Jing Huang Tinglei Wang Hongqi 《Journal of Electronics(China)》 2014年第6期565-575,共11页
Topic models such as Latent Dirichlet Allocation(LDA) have been successfully applied to many text mining tasks for extracting topics embedded in corpora. However, existing topic models generally cannot discover bursty... Topic models such as Latent Dirichlet Allocation(LDA) have been successfully applied to many text mining tasks for extracting topics embedded in corpora. However, existing topic models generally cannot discover bursty topics that experience a sudden increase during a period of time. In this paper, we propose a new topic model named Burst-LDA, which simultaneously discovers topics and reveals their burstiness through explicitly modeling each topic's burst states with a first order Markov chain and using the chain to generate the topic proportion of documents in a Logistic Normal fashion. A Gibbs sampling algorithm is developed for the posterior inference of the proposed model. Experimental results on a news data set show our model can efficiently discover bursty topics, outperforming the state-of-the-art method. 展开更多
关键词 Text mining Burst detection Topic model graphical model Bayesian inference
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Highly Regional Genes:graph-based gene selection for single-cell RNA-seq data 被引量:1
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作者 Yanhong Wu Qifan Hu +6 位作者 Shicheng Wang Changyi Liu Yiran Shan Wenbo Guo Rui Jiang Xiaowo Wang Jin Gu 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2022年第9期891-899,共9页
Gene selection is an indispensable step for analyzing noisy and high-dimensional single-cell RNA-seq(scRNA-seq)data.Compared with the commonly used variance-based methods,by mimicking the human maker selection in the ... Gene selection is an indispensable step for analyzing noisy and high-dimensional single-cell RNA-seq(scRNA-seq)data.Compared with the commonly used variance-based methods,by mimicking the human maker selection in the 2D visualization of cells,a new feature selection method called HRG(Highly Regional Genes)is proposed to find the informative genes,which show regional expression patterns in the cell-cell similarity network.We mathematically find the optimal expression patterns that can maximize the proposed scoring function.In comparison with several unsupervised methods,HRG shows high accuracy and robustness,and can increase the performance of downstream cell clustering and gene correlation analysis.Also,it is applicable for selecting informative genes of sequencing-based spatial transcriptomic data. 展开更多
关键词 Single-cell RNA-sequencing Feature selection Spatially resolved transcriptomic data Regional patterns graphical models
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A framework for computer vision-based health monitoring of a truss structure subjected to unknown excitations 被引量:1
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作者 Mariusz Ostrowski Bartlomiej Blachowski +3 位作者 Bartosz Wójcik Mateusz Żarski Piotr Tauzowski Łukasz Jankowski 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2023年第1期1-17,共17页
Computer vision(CV)methods for measurement of structural vibration are less expensive,and their application is more straightforward than methods based on sensors that measure physical quantities at particular points o... Computer vision(CV)methods for measurement of structural vibration are less expensive,and their application is more straightforward than methods based on sensors that measure physical quantities at particular points of a structure.However,CV methods produce significantly more measurement errors.Thus,computer vision-based structural health monitoring(CVSHM)requires appropriate methods of damage assessment that are robust with respect to highly contaminated measurement data.In this paper a complete CVSHM framework is proposed,and three damage assessment methods are tested.The first is the augmented inverse estimate(AIE),proposed by Peng et al.in 2021.This method is designed to work with highly contaminated measurement data,but it fails with a large noise provided by CV measurement.The second method,as proposed in this paper,is based on the AIE,but it introduces a weighting matrix that enhances the conditioning of the problem.The third method,also proposed in this paper,introduces additional constraints in the optimization process;these constraints ensure that the stiffness of structural elements can only decrease.Both proposed methods perform better than the original AIE.The latter of the two proposed methods gives the best results,and it is robust with respect to the selected coefficients,as required by the algorithm. 展开更多
关键词 computer vision structural health monitoring physics-based graphical models augmented inverse estimate model updating non-negative least square method
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Mining Data Correlation from Multi-Faceted Sensor Data in Internet of Things 被引量:1
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作者 曹栋 乔秀全 +2 位作者 Judith Gelernter 李晓峰 孟洛明 《China Communications》 SCIE CSCD 2011年第1期132-138,共7页
Sensors are ubiquitous in the Internet of Things for measuring and collecting data. Analyzing these data derived from sensors is an essential task and can reveal useful latent information besides the data. Since the I... Sensors are ubiquitous in the Internet of Things for measuring and collecting data. Analyzing these data derived from sensors is an essential task and can reveal useful latent information besides the data. Since the Internet of Things contains many sorts of sensors, the measurement data collected by these sensors are multi-type data, sometimes contai- ning temporal series information. If we separately deal with different sorts of data, we will miss useful information. This paper proposes a method to dis- cover the correlation in multi-faceted data, which contains many types of data with temporal informa- tion, and our method can simultaneously deal with multi-faceted data. We transform high-dimensional multi-faeeted data into lower-dimensional data which is set as multivariate Gaussian Graphical Models, then mine the correlation in multi-faceted data by discover the structure of the multivariate Gausslan Graphical Models. With a real data set, we verifies our method, and the experiment demonstrates that the method we propose can correctly fred out the correlation among multi-faceted meas- urement data. 展开更多
关键词 multi-faceted data SENSORS Internet of Things Gaussian graphical Models
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Seed Selection for Data Offloading Based on Social and Interest Graphs 被引量:1
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作者 Ying Li Jianbo Li +2 位作者 Jianwei Chen Minchao Lu Caoyuan Li 《Computers, Materials & Continua》 SCIE EI 2018年第12期571-587,共17页
The explosive growth of mobile data demand is becoming an increasing burden on current cellular network.To address this issue,we propose a solution of opportunistic data offloading for alleviating overloaded cellular ... The explosive growth of mobile data demand is becoming an increasing burden on current cellular network.To address this issue,we propose a solution of opportunistic data offloading for alleviating overloaded cellular traffic.The principle behind it is to select a few important users as seeds for data sharing.The three critical steps are detailed as follows.We first explore individual interests of users by the construction of user profiles,on which an interest graph is built by Gaussian graphical modeling.We then apply the extreme value theory to threshold the encounter duration of user pairs.So,a contact graph is generated to indicate the social relationships of users.Moreover,a contact-interest graph is developed on the basis of the social ties and individual interests of users.Corresponding on different graphs,three strategies are finally proposed for seed selection in an aim to maximize overloaded cellular data.We evaluate the performance of our algorithms by the trace data of real-word mobility.It demonstrates the effectiveness of the strategy of taking social relationships and individual interests into account. 展开更多
关键词 Mobile social network social data offloading extreme value model Gaussian graphical model
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Modeling correlated samples via sparse matrix Gaussian graphical models 被引量:1
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作者 Yi-zhou HE Xi CHEN Hao WANG 《Journal of Zhejiang University-Science C(Computers and Electronics)》 SCIE EI 2013年第2期107-117,共11页
A new procedure of learning in Gaussian graphical models is proposed under the assumption that samples are possibly dependent.This assumption,which is pragmatically applied in various areas of multivariate analysis ra... A new procedure of learning in Gaussian graphical models is proposed under the assumption that samples are possibly dependent.This assumption,which is pragmatically applied in various areas of multivariate analysis ranging from bioinformatics to finance,makes standard Gaussian graphical models(GGMs) unsuitable.We demonstrate that the advantage of modeling dependence among samples is that the true discovery rate and positive predictive value are improved substantially than if standard GGMs are applied and the dependence among samples is ignored.The new method,called matrix-variate Gaussian graphical models(MGGMs),involves simultaneously modeling variable and sample dependencies with the matrix-normal distribution.The computation is carried out using a Markov chain Monte Carlo(MCMC) sampling scheme for graphical model determination and parameter estimation.Simulation studies and two real-world examples in biology and finance further illustrate the benefits of the new models. 展开更多
关键词 Gaussian graphical models Hyper-inverse Wishart distributions Mutual fund evaluation NETWORK
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An integrative multivariate approach for predicting functional recovery using magnetic resonance imaging parameters in a translational pig ischemic stroke model
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作者 Erin E.Kaiser J.C.Poythress +6 位作者 Kelly M.Scheulin Brian J.Jurgielewicz Nicole A.Lazar Cheolwoo Park Steven L.Stice Jeongyoun Ahn Franklin D.West 《Neural Regeneration Research》 SCIE CAS CSCD 2021年第5期842-850,共9页
Magnetic resonance imaging(MRI)is a clinically relevant,real-time imaging modality that is frequently utilized to assess stroke type and severity.However,specific MRI biomarkers that can be used to predict long-term f... Magnetic resonance imaging(MRI)is a clinically relevant,real-time imaging modality that is frequently utilized to assess stroke type and severity.However,specific MRI biomarkers that can be used to predict long-term functional recovery are still a critical need.Consequently,the present study sought to examine the prognostic value of commonly utilized MRI parameters to predict functional outcomes in a porcine model of ischemic stroke.Stroke was induced via permanent middle cerebral artery occlusion.At 24 hours post-stroke,MRI analysis revealed focal ischemic lesions,decreased diffusivity,hemispheric swelling,and white matter degradation.Functional deficits including behavioral abnormalities in open field and novel object exploration as well as spatiotemporal gait impairments were observed at 4 weeks post-stroke.Gaussian graphical models identified specific MRI outputs and functional recovery variables,including white matter integrity and gait performance,that exhibited strong conditional dependencies.Canonical correlation analysis revealed a prognostic relationship between lesion volume and white matter integrity and novel object exploration and gait performance.Consequently,these analyses may also have the potential of predicting patient recovery at chronic time points as pigs and humans share many anatomical similarities(e.g.,white matter composition)that have proven to be critical in ischemic stroke pathophysiology.The study was approved by the University of Georgia(UGA)Institutional Animal Care and Use Committee(IACUC;Protocol Number:A2014-07-021-Y3-A11 and 2018-01-029-Y1-A5)on November 22,2017. 展开更多
关键词 behavior testing canonical correlation analysis gait analysis Gaussian graphical models ischemic stroke magnetic resonance imaging pig model principal component analysis
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