In this paper, we study the inertial manifolds for a class of the Kirchhoff-type equations with strongly damped terms and source terms. The inertial manifold is a finite dimensional invariant smooth manifold that cont...In this paper, we study the inertial manifolds for a class of the Kirchhoff-type equations with strongly damped terms and source terms. The inertial manifold is a finite dimensional invariant smooth manifold that contains the global attractor, attracting the solution orbits by the exponential rate. Under appropriate assumptions, we firstly exert the Hadamard’s graph transformation method to structure a graph norm of a Lipschitz continuous function, and then we prove the existence of the inertial manifold by showing that the spectral gap condition is true.展开更多
Aims: Steadily the clinicians of our team in inflammatory bowel disease encounter ulcerative colitis patients that develop deep ulcers during their treatment. Currently, these practitioners are only equipped with thei...Aims: Steadily the clinicians of our team in inflammatory bowel disease encounter ulcerative colitis patients that develop deep ulcers during their treatment. Currently, these practitioners are only equipped with their grade of expertise in inflammatory domains to decide what new therapy maybe use in such cases. Encouraged by the limited knowledge of this frequent pathology, we seek to determine the molecular conditions underlying the recurrent formation of deep ulcerations in certain group of patients. Method: The goal of this strategy is to expose differences between groups of patients based on similarities computed by random walk graph kernels and performing functional inference on those differences. Results: We apply the methodology to a cohort of eleven miRNA microarrays of ulcerative colitis patients. Our results showed how the group of ulcerative colitis patients with presence of deep ulcers is topologically more similar (0.35) than ulcerative colitis patients (0.18) to control. Such topological constraint drove functional inference to complete the information that clinicians need. Conclusions: Our analyses reveal highly interpretable in the guidance of practitioners to eventually correct initial therapies of ulcerative colitis patients that develop deep ulcers. The methodology can provide them with useful molecular hypotheses necessaries prior to make any decision on the newest course of the treatment.展开更多
In this paper, we study the inertial manifolds for a class of asymmetrically coupled generalized Higher-order Kirchhoff equations. Under appropriate assumptions, we firstly exist Hadamard’s graph transformation metho...In this paper, we study the inertial manifolds for a class of asymmetrically coupled generalized Higher-order Kirchhoff equations. Under appropriate assumptions, we firstly exist Hadamard’s graph transformation method to structure a graph norm of a Lipschitz continuous function, then we prove the existence of a family of inertial manifolds by showing that the spectral gap condition is true.展开更多
文摘In this paper, we study the inertial manifolds for a class of the Kirchhoff-type equations with strongly damped terms and source terms. The inertial manifold is a finite dimensional invariant smooth manifold that contains the global attractor, attracting the solution orbits by the exponential rate. Under appropriate assumptions, we firstly exert the Hadamard’s graph transformation method to structure a graph norm of a Lipschitz continuous function, and then we prove the existence of the inertial manifold by showing that the spectral gap condition is true.
文摘Aims: Steadily the clinicians of our team in inflammatory bowel disease encounter ulcerative colitis patients that develop deep ulcers during their treatment. Currently, these practitioners are only equipped with their grade of expertise in inflammatory domains to decide what new therapy maybe use in such cases. Encouraged by the limited knowledge of this frequent pathology, we seek to determine the molecular conditions underlying the recurrent formation of deep ulcerations in certain group of patients. Method: The goal of this strategy is to expose differences between groups of patients based on similarities computed by random walk graph kernels and performing functional inference on those differences. Results: We apply the methodology to a cohort of eleven miRNA microarrays of ulcerative colitis patients. Our results showed how the group of ulcerative colitis patients with presence of deep ulcers is topologically more similar (0.35) than ulcerative colitis patients (0.18) to control. Such topological constraint drove functional inference to complete the information that clinicians need. Conclusions: Our analyses reveal highly interpretable in the guidance of practitioners to eventually correct initial therapies of ulcerative colitis patients that develop deep ulcers. The methodology can provide them with useful molecular hypotheses necessaries prior to make any decision on the newest course of the treatment.
文摘In this paper, we study the inertial manifolds for a class of asymmetrically coupled generalized Higher-order Kirchhoff equations. Under appropriate assumptions, we firstly exist Hadamard’s graph transformation method to structure a graph norm of a Lipschitz continuous function, then we prove the existence of a family of inertial manifolds by showing that the spectral gap condition is true.
