The paper discusses the characteristics of next generation services, and analyzes its development barriers and cut-in points.Broadband services that NGN offers have to transit from an unknown state to an popular state...The paper discusses the characteristics of next generation services, and analyzes its development barriers and cut-in points.Broadband services that NGN offers have to transit from an unknown state to an popular state to become a scale economy.Personal information and communication services and multimedia entertainment services will be the cut-in points.展开更多
Generation of mouse models carrying a defined point mutation,especially disease-related point mutations,is of considerable interest for research in biology and medicine.The standard method based on embryonic stem cell...Generation of mouse models carrying a defined point mutation,especially disease-related point mutations,is of considerable interest for research in biology and medicine.The standard method based on embryonic stem cell(ESC)-mediated homologous recombination(HR)is time-and labor-consuming.展开更多
A conduction heat transfer process is enhanced by filling prescribed quantity and optimized-shaped high thermal conductivity materials to the substrate. Numerical simulations and analyses are performed on a volume to ...A conduction heat transfer process is enhanced by filling prescribed quantity and optimized-shaped high thermal conductivity materials to the substrate. Numerical simulations and analyses are performed on a volume to point conduction problem based on the principle of minimum entropy generation. In the optimization, the arrangement of high thermal conductivity materials is variable, the quantity of high thermal-conductivity material is constrained, and the objective is to obtain the maximum heat conduction rate as the entropy is the minimum.A novel algorithm of thermal conductivity discretization is proposed based on large quantity of calculations.Compared with other algorithms in literature, the average temperature in the substrate by the new algorithm is lower, while the highest temperature in the substrate is in a reasonable range. Thus the new algorithm is feasible. The optimization of volume to point heat conduction is carried out in a rectangular model with radiation boundary condition and constant surface temperature boundary condition. The results demonstrate that the algorithm of thermal conductivity discretization is applicable for volume to point heat conduction problems.展开更多
We solve numerically an eigenvalue elliptic partial differential equation(PDE)ranging from two to six dimensions using the generalized multiquadric(GMQ)radial basis functions(RBFs).Two discretization methods are em-pl...We solve numerically an eigenvalue elliptic partial differential equation(PDE)ranging from two to six dimensions using the generalized multiquadric(GMQ)radial basis functions(RBFs).Two discretization methods are em-ployed.The first method is similar to the classic mesh-based discretization method requiring n centers per dimension or a total ndpoints.The second method is based upon n randomly generated points in dℜrequiring far fewer data centers than the classic mesh method.Instead of having a crisp boundary,we form a“fuzzy”boundary.Using the analytic or numerical in-verse interior and boundary operators,we find the local and global minima and maxima to cull discretization points.We also find that the GMQ-RBF“flatness”can be controlled by increasing the GMQ exponential,β.We per-form a search to find the smallest root mean squared error(RMSE)by varying the exponent,the maximum,the minimum range of the GMQ shape parame-ter,and boundary influence,with the exponential having the most influence.Because the GMQ-RBFs are essentially nonlinear,it follows that the starting point of the simple search influences the end result.The optimal algorithm for high dimensional PDEs is still the subject of much research and may wait for the common place availability of massively parallel quantum computers for even higher dimensional PDEs and integral equations(IEs).展开更多
文摘The paper discusses the characteristics of next generation services, and analyzes its development barriers and cut-in points.Broadband services that NGN offers have to transit from an unknown state to an popular state to become a scale economy.Personal information and communication services and multimedia entertainment services will be the cut-in points.
基金supported by the Ministry of Science and Technology of China (2014CB964803 and 2015AA020307)the National Natural Science Foundation of China (Nos. 31530048, 31601163 and 81672117)+1 种基金he Chinese Academy of Sciences (XDB19010204 and QYZDJ-SSW-SMC023)the Shanghai Municipal Commission for Science and Technology(16JC1420500, 17JC1400900 and 17140901500)
文摘Generation of mouse models carrying a defined point mutation,especially disease-related point mutations,is of considerable interest for research in biology and medicine.The standard method based on embryonic stem cell(ESC)-mediated homologous recombination(HR)is time-and labor-consuming.
基金Supported by the National Key Basic Research Program of China(2013CB228305)
文摘A conduction heat transfer process is enhanced by filling prescribed quantity and optimized-shaped high thermal conductivity materials to the substrate. Numerical simulations and analyses are performed on a volume to point conduction problem based on the principle of minimum entropy generation. In the optimization, the arrangement of high thermal conductivity materials is variable, the quantity of high thermal-conductivity material is constrained, and the objective is to obtain the maximum heat conduction rate as the entropy is the minimum.A novel algorithm of thermal conductivity discretization is proposed based on large quantity of calculations.Compared with other algorithms in literature, the average temperature in the substrate by the new algorithm is lower, while the highest temperature in the substrate is in a reasonable range. Thus the new algorithm is feasible. The optimization of volume to point heat conduction is carried out in a rectangular model with radiation boundary condition and constant surface temperature boundary condition. The results demonstrate that the algorithm of thermal conductivity discretization is applicable for volume to point heat conduction problems.
文摘We solve numerically an eigenvalue elliptic partial differential equation(PDE)ranging from two to six dimensions using the generalized multiquadric(GMQ)radial basis functions(RBFs).Two discretization methods are em-ployed.The first method is similar to the classic mesh-based discretization method requiring n centers per dimension or a total ndpoints.The second method is based upon n randomly generated points in dℜrequiring far fewer data centers than the classic mesh method.Instead of having a crisp boundary,we form a“fuzzy”boundary.Using the analytic or numerical in-verse interior and boundary operators,we find the local and global minima and maxima to cull discretization points.We also find that the GMQ-RBF“flatness”can be controlled by increasing the GMQ exponential,β.We per-form a search to find the smallest root mean squared error(RMSE)by varying the exponent,the maximum,the minimum range of the GMQ shape parame-ter,and boundary influence,with the exponential having the most influence.Because the GMQ-RBFs are essentially nonlinear,it follows that the starting point of the simple search influences the end result.The optimal algorithm for high dimensional PDEs is still the subject of much research and may wait for the common place availability of massively parallel quantum computers for even higher dimensional PDEs and integral equations(IEs).