Objective To describe phenotype, perioperative events, and early morbidity among infants with esophageal atresia with or without tracheoesophageal fistula(EA/TEF), and to evaluate how gap length relates to postoperati...Objective To describe phenotype, perioperative events, and early morbidity among infants with esophageal atresia with or without tracheoesophageal fistula(EA/TEF), and to evaluate how gap length relates to postoperative and follow-up outcomes.Methods A retrospective single-center cohort study was conducted in a tertiary neonatal and pediatric surgery service, Riyadh, Saudi Arabia. All infants with EA/TEF managed between January 1, 2016 and December 31, 2024. Clinical data include early clinical anastomotic leak(≤14 days), recurrent fistula, anastomotic stricture and time-to-event outcomes including hospital length of stay, time to full oral feeding, duration of postoperative ventilation and duration of parenteral nutrition. Followup outcomes included respiratory morbidity and feeding support requirements.Results Sixty-seven infants were included;gross type C was most frequent(73.1%). Gap length was assessable in 63 non-H-type cases, with 31.7% classified as long-gap EA. Survival to discharge was 86% after excluding three trisomy 18 infants managed palliatively. Primary repair was achieved in 67.2% overall but in only 10% of long-gap infants, among whom staged repair or gastric pull-up predominated. Early anastomotic leak occurred in 26.9%, recurrent fistula in 14.9% and anastomotic stricture in 32.8%. In multivariable logistic regression, long-gap EA was the only independent predictor of stricture(adjusted odds ratio(OR) 4.44;95% confidence interval(CI) 1.27 to 15.55;p=0.020). Recovery was substantially longer for long-gap infants: median hospital stay 186 vs. 53 days(p<0.001) and time to full oral feeding 209 vs. 29 days(p<0.001). At follow-up(n=55), 34.5% required gastrostomy, 20% had feeding aversion, 36.4% experienced recurrent respiratory infections, and 10.9% had tracheomalacia.Conclusions Gap length was the principal determinant of anastomotic stricture and prolonged recovery after EA/TEF repair. These data provide a baseline for ongoing quality improvement and support early referral of long-gap cases to specialized multidisciplinary centers with structured follow-up programs.展开更多
Assuming some known nucleon-nucleon interactions, and using the relations between phase shift δ and nucleon-nucleon interaction potential V (r);the relation between nucleon-nucleon interaction and scattering length a...Assuming some known nucleon-nucleon interactions, and using the relations between phase shift δ and nucleon-nucleon interaction potential V (r);the relation between nucleon-nucleon interaction and scattering length a;the relation between energy gap Δ, and scattering length a;an equation is obtained between energy gap Δ and Fermi momentum kF via the phase shift δ (kF). Assuming 1s0 (singlet) pairing between the nucleons, the energy gap Δ has been calculated and it is found that Δ = 3.0 MeV at Fermi momentum kF = 0.8 fm-1.展开更多
具有通配符间隙约束的模式匹配问题在信息检索、计算生物学和序列模式挖掘等研究领域有重要的应用.提出了更一般性的模式匹配问题,即一般间隙和长度约束的严格模式匹配(strict pattern matching with general gaps and length constrain...具有通配符间隙约束的模式匹配问题在信息检索、计算生物学和序列模式挖掘等研究领域有重要的应用.提出了更一般性的模式匹配问题,即一般间隙和长度约束的严格模式匹配(strict pattern matching with general gaps and length constraints,简称SPANGLO).该问题具有如下4个特点:它是一种严格的精确模式匹配;允许序列中任意位置的字符被多次使用;模式串中可以包含多个一般间隙;对出现的总体长度进行了约束.最坏情况下,一个SPANGLO实例将转换出指数个非负间隙的严格模式匹配实例.为了有效地解决该问题,提出了子网树及其相关概念和性质.在此基础上提出了求解算法SubnettreeSpanglo(SETS),并给出算法的正确性和完备性证明,同时指出该算法的空间复杂度与时间复杂度分别为O(m MaxLen W)和O(MaxLen W m2 n),其中,m,n,MaxLen和W分别是模式和序列的长度、出现的最大长度约束和模式的最大间距.实验结果既验证了SPANGLO问题转换方法的正确性,又验证了该算法的正确性和有效性.展开更多
金属丝电爆炸放电波形研究是分析负载能量耦合效率等特性的基础。为此,采用步进电机驱动金属丝端部向高压平板电极运动,通过高压电场击穿环境气体,将大电流导入金属丝中,完成电爆炸。基于该实验方案,提出了一种金属丝电极向高压电极运...金属丝电爆炸放电波形研究是分析负载能量耦合效率等特性的基础。为此,采用步进电机驱动金属丝端部向高压平板电极运动,通过高压电场击穿环境气体,将大电流导入金属丝中,完成电爆炸。基于该实验方案,提出了一种金属丝电极向高压电极运动过程中、环境气体击穿时,两电极间气隙长度的计算方法。并利用电路模型对氩气中铝电爆炸丝放电电流进行了数值模拟,最后分析了不同实验因素(充电电压、金属丝直径及充气压力)对放电电流波形的影响。结果表明:将计算得到的气隙长度代入电路模型,模拟得到的金属丝放电电流波形与实验测量结果基本相符;当充电电压由20 k V提高到28 k V时,放电电流峰值、上升速度分别增大了约6 k A、10 k A/μs,金属蒸汽击穿时刻提前了近0.4μs;当氩气气压从0.10 MPa提升到0.20 MPa时,金属蒸汽击穿时刻由1.5μs推迟到2.1μs。展开更多
文摘Objective To describe phenotype, perioperative events, and early morbidity among infants with esophageal atresia with or without tracheoesophageal fistula(EA/TEF), and to evaluate how gap length relates to postoperative and follow-up outcomes.Methods A retrospective single-center cohort study was conducted in a tertiary neonatal and pediatric surgery service, Riyadh, Saudi Arabia. All infants with EA/TEF managed between January 1, 2016 and December 31, 2024. Clinical data include early clinical anastomotic leak(≤14 days), recurrent fistula, anastomotic stricture and time-to-event outcomes including hospital length of stay, time to full oral feeding, duration of postoperative ventilation and duration of parenteral nutrition. Followup outcomes included respiratory morbidity and feeding support requirements.Results Sixty-seven infants were included;gross type C was most frequent(73.1%). Gap length was assessable in 63 non-H-type cases, with 31.7% classified as long-gap EA. Survival to discharge was 86% after excluding three trisomy 18 infants managed palliatively. Primary repair was achieved in 67.2% overall but in only 10% of long-gap infants, among whom staged repair or gastric pull-up predominated. Early anastomotic leak occurred in 26.9%, recurrent fistula in 14.9% and anastomotic stricture in 32.8%. In multivariable logistic regression, long-gap EA was the only independent predictor of stricture(adjusted odds ratio(OR) 4.44;95% confidence interval(CI) 1.27 to 15.55;p=0.020). Recovery was substantially longer for long-gap infants: median hospital stay 186 vs. 53 days(p<0.001) and time to full oral feeding 209 vs. 29 days(p<0.001). At follow-up(n=55), 34.5% required gastrostomy, 20% had feeding aversion, 36.4% experienced recurrent respiratory infections, and 10.9% had tracheomalacia.Conclusions Gap length was the principal determinant of anastomotic stricture and prolonged recovery after EA/TEF repair. These data provide a baseline for ongoing quality improvement and support early referral of long-gap cases to specialized multidisciplinary centers with structured follow-up programs.
文摘Assuming some known nucleon-nucleon interactions, and using the relations between phase shift δ and nucleon-nucleon interaction potential V (r);the relation between nucleon-nucleon interaction and scattering length a;the relation between energy gap Δ, and scattering length a;an equation is obtained between energy gap Δ and Fermi momentum kF via the phase shift δ (kF). Assuming 1s0 (singlet) pairing between the nucleons, the energy gap Δ has been calculated and it is found that Δ = 3.0 MeV at Fermi momentum kF = 0.8 fm-1.
文摘具有通配符间隙约束的模式匹配问题在信息检索、计算生物学和序列模式挖掘等研究领域有重要的应用.提出了更一般性的模式匹配问题,即一般间隙和长度约束的严格模式匹配(strict pattern matching with general gaps and length constraints,简称SPANGLO).该问题具有如下4个特点:它是一种严格的精确模式匹配;允许序列中任意位置的字符被多次使用;模式串中可以包含多个一般间隙;对出现的总体长度进行了约束.最坏情况下,一个SPANGLO实例将转换出指数个非负间隙的严格模式匹配实例.为了有效地解决该问题,提出了子网树及其相关概念和性质.在此基础上提出了求解算法SubnettreeSpanglo(SETS),并给出算法的正确性和完备性证明,同时指出该算法的空间复杂度与时间复杂度分别为O(m MaxLen W)和O(MaxLen W m2 n),其中,m,n,MaxLen和W分别是模式和序列的长度、出现的最大长度约束和模式的最大间距.实验结果既验证了SPANGLO问题转换方法的正确性,又验证了该算法的正确性和有效性.
文摘金属丝电爆炸放电波形研究是分析负载能量耦合效率等特性的基础。为此,采用步进电机驱动金属丝端部向高压平板电极运动,通过高压电场击穿环境气体,将大电流导入金属丝中,完成电爆炸。基于该实验方案,提出了一种金属丝电极向高压电极运动过程中、环境气体击穿时,两电极间气隙长度的计算方法。并利用电路模型对氩气中铝电爆炸丝放电电流进行了数值模拟,最后分析了不同实验因素(充电电压、金属丝直径及充气压力)对放电电流波形的影响。结果表明:将计算得到的气隙长度代入电路模型,模拟得到的金属丝放电电流波形与实验测量结果基本相符;当充电电压由20 k V提高到28 k V时,放电电流峰值、上升速度分别增大了约6 k A、10 k A/μs,金属蒸汽击穿时刻提前了近0.4μs;当氩气气压从0.10 MPa提升到0.20 MPa时,金属蒸汽击穿时刻由1.5μs推迟到2.1μs。
