The extended homoclinic test function method is a kind of classic, efficient and well-developed method to solve nonlinear evolution equations. In this paper, with the help of this approach, we obtain new exact solutio...The extended homoclinic test function method is a kind of classic, efficient and well-developed method to solve nonlinear evolution equations. In this paper, with the help of this approach, we obtain new exact solutions （including kinky periodic solitary-wave solutions, periodic soliton solutions, and cross kink-wave solutions） for the new （2＋1）-dimensional KdV equation. These results enrich the variety of the dynamics of higher-dimensionai nonlinear wave field.展开更多
We focus on the localized characteristics of lump and interaction solutions to two extended Jimbo–Miwa equations.Based on the Hirota bilinear method and the test function method,we construct the exact solutions to th...We focus on the localized characteristics of lump and interaction solutions to two extended Jimbo–Miwa equations.Based on the Hirota bilinear method and the test function method,we construct the exact solutions to the extended equations including lump solutions,lump–kink solutions,and two other types of interaction solutions,by solving the underdetermined nonlinear system of algebraic equations for associated parameters.Finally,analysis and graphical simulation are presented to show the dynamical characteristics of our solutions and the interaction behaviors are revealed.展开更多
Objective：A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced.The proposed method for the estimation of parameters for...Objective：A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced.The proposed method for the estimation of parameters for a system of ordinary differential equations（ODEs）that represent the time course of plasma glucose and insulin concentrations during glucose tolerance test（GTT）in physiological studies is presented.The aim of this study was to explore how to interpret those laboratory glucose and insulin data as well as enhance the Ackerman mathematical model.Methods：Parameters estimation for a system of ODEs was performed by minimizing the sum of squared residuals（SSR）function,which quantifies the difference between theoretical model predictions and GTT＇s experimental observations.Our proposed perturbation search and multiple-shooting methods were applied during the estimating process.Results：Based on the Ackerman＇s published data,we estimated the key parameters by applying R-based iterative computer programs.As a result,the theoretically simulated curves perfectly matched the experimental data points.Our model showed that the estimated parameters,computed frequency and period values,were proven a good indicator of diabetes.Conclusion：The present paper introduces a computational algorithm to biomedical problems,particularly to endocrinology and metabolism fields,which involves two coupled differential equations with four parameters describing the glucose-insulin regulatory system that Ackerman proposed earlier.The enhanced approach may provide clinicians in endocrinology and metabolism field insight into the transition nature of human metabolic mechanism from normal to impaired glucose tolerance.展开更多
The main purpose of this paper is to investigate the singularities of solutions to the single Tricomi equation with derivative term and combined memory term.In addition,the blow-up of the solution to the weakly couple...The main purpose of this paper is to investigate the singularities of solutions to the single Tricomi equation with derivative term and combined memory term.In addition,the blow-up of the solution to the weakly coupled system with memory term is also considered,where one is a power nonlinear term and the other is a derivative nonlinear term.Upper bound lifespan estimates of solution are obtained in the sub-critical by utilizing the test function method and iteration technique.The innovation of this paper focuses on the lifespan estimates of the solutions,which extends the well-known Strauss and Glassey conjectures.展开更多
This paper deals with a coupled system of fourth-order parabolic inequalities ｜u｜t ≥ -△2^u＋｜v｜^q, ｜v｜t ≥-△2v＋｜u｜p^ in S=R^n ×R^＋ withp, q 〉 1, n ≥1. AFujita- Liouville type theorem is establishe...This paper deals with a coupled system of fourth-order parabolic inequalities ｜u｜t ≥ -△2^u＋｜v｜^q, ｜v｜t ≥-△2v＋｜u｜p^ in S=R^n ×R^＋ withp, q 〉 1, n ≥1. AFujita- Liouville type theorem is established that the inequality system does not admit nontrivial nonnegative global solutions on S whenever n/4≤ max（ p＋1/pq-1, q＋1/pq-1 ）. Since the general maximum-comparison principle does not hold for the fourth-order problem, the authors use the test function method to get the global non-existence of nontrivial solutions.展开更多
基金Supported by the Natural Science Foundation of China under Grant Nos.10361007,10661002Yunnan Natural Science Foundation under Grant No.2006A0082M
文摘The extended homoclinic test function method is a kind of classic, efficient and well-developed method to solve nonlinear evolution equations. In this paper, with the help of this approach, we obtain new exact solutions （including kinky periodic solitary-wave solutions, periodic soliton solutions, and cross kink-wave solutions） for the new （2＋1）-dimensional KdV equation. These results enrich the variety of the dynamics of higher-dimensionai nonlinear wave field.
基金Project supported by the Fundamental Research Funds for the Central Universities of China(Grant No.2018RC031)the National Natural Science Foundation of China(Grant No.71971015)+1 种基金the Program of the Co-Construction with Beijing Municipal Commission of Education of China(Grant Nos.B19H100010and B18H100040)the Open Fund of IPOC(BUPT)。
文摘We focus on the localized characteristics of lump and interaction solutions to two extended Jimbo–Miwa equations.Based on the Hirota bilinear method and the test function method,we construct the exact solutions to the extended equations including lump solutions,lump–kink solutions,and two other types of interaction solutions,by solving the underdetermined nonlinear system of algebraic equations for associated parameters.Finally,analysis and graphical simulation are presented to show the dynamical characteristics of our solutions and the interaction behaviors are revealed.
基金supported by a grant from the NIH(No.U42 RR16607)
文摘Objective：A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced.The proposed method for the estimation of parameters for a system of ordinary differential equations（ODEs）that represent the time course of plasma glucose and insulin concentrations during glucose tolerance test（GTT）in physiological studies is presented.The aim of this study was to explore how to interpret those laboratory glucose and insulin data as well as enhance the Ackerman mathematical model.Methods：Parameters estimation for a system of ODEs was performed by minimizing the sum of squared residuals（SSR）function,which quantifies the difference between theoretical model predictions and GTT＇s experimental observations.Our proposed perturbation search and multiple-shooting methods were applied during the estimating process.Results：Based on the Ackerman＇s published data,we estimated the key parameters by applying R-based iterative computer programs.As a result,the theoretically simulated curves perfectly matched the experimental data points.Our model showed that the estimated parameters,computed frequency and period values,were proven a good indicator of diabetes.Conclusion：The present paper introduces a computational algorithm to biomedical problems,particularly to endocrinology and metabolism fields,which involves two coupled differential equations with four parameters describing the glucose-insulin regulatory system that Ackerman proposed earlier.The enhanced approach may provide clinicians in endocrinology and metabolism field insight into the transition nature of human metabolic mechanism from normal to impaired glucose tolerance.
基金Supported by National Natural Science Foundation of China Under Grant(12401647)Supported by Fundamental Research Program of Shanxi Province(202203021212336)+2 种基金Taiyuan Institute of Technology Scientific Research Initial Funding(2023KJ057,2024KJ007,2024LJ005)Supported by Scientific and Technologial Innovation Programs of Higher Education Institutions in Shanxi(2024L358)Youth Program of Taiyuan University(24TYQN10)。
文摘The main purpose of this paper is to investigate the singularities of solutions to the single Tricomi equation with derivative term and combined memory term.In addition,the blow-up of the solution to the weakly coupled system with memory term is also considered,where one is a power nonlinear term and the other is a derivative nonlinear term.Upper bound lifespan estimates of solution are obtained in the sub-critical by utilizing the test function method and iteration technique.The innovation of this paper focuses on the lifespan estimates of the solutions,which extends the well-known Strauss and Glassey conjectures.
基金supported by the National Natural Science Foundation of China (Nos. 10771024,11171048)the Fundamental Research Funds for the Central Universities (No. 851011)
文摘This paper deals with a coupled system of fourth-order parabolic inequalities ｜u｜t ≥ -△2^u＋｜v｜^q, ｜v｜t ≥-△2v＋｜u｜p^ in S=R^n ×R^＋ withp, q 〉 1, n ≥1. AFujita- Liouville type theorem is established that the inequality system does not admit nontrivial nonnegative global solutions on S whenever n/4≤ max（ p＋1/pq-1, q＋1/pq-1 ）. Since the general maximum-comparison principle does not hold for the fourth-order problem, the authors use the test function method to get the global non-existence of nontrivial solutions.
