Objective:To systematically review the current implementation status of nurses’non-pharmacological prescription authority and analyze the barriers encountered during its implementation in China,providing countermeasu...Objective:To systematically review the current implementation status of nurses’non-pharmacological prescription authority and analyze the barriers encountered during its implementation in China,providing countermeasures and references for promoting the standardized implementation of nurses’non-pharmacological prescription authority.Methods:A secondary analysis of literature was conducted to systematically search for domestic and international literature related to nurses’non-pharmacological prescription authority.Meta-analysis was performed on eligible literature to evaluate the implementation effects.Simultaneously,semi-structured in-depth interviews were conducted with healthcare workers,patients,and policymakers.Content analysis was used to organize the interview data and extract core issues and barriers.Results:A total of 46 international articles were included in the Meta-analysis,which revealed that the implementation of nurses’non-pharmacological prescription authority significantly improved patients’health management outcomes,enhanced healthcare service efficiency,and increased patient satisfaction.Conclusion:The implementation of nurses’non-pharmacological prescription authority has demonstrated significant positive effects.However,China faces multiple barriers in its advancement,necessitating efforts in optimizing policy systems,constructing collaborative models,strengthening professional skills training,and improving social awareness to guide the scientific and rational implementation of nurses’non-pharmacological prescription authority.展开更多
Taking the rural low-income population of Zhejiang Province as its subject, this paper examines how to build a sustainable income-growth mechanism and identify feasible implementation paths within the context of the c...Taking the rural low-income population of Zhejiang Province as its subject, this paper examines how to build a sustainable income-growth mechanism and identify feasible implementation paths within the context of the common prosperity strategy. The research identifies key obstacles to income expansion, including an undiversified industrial structure, insufficient human capital, and a lack of robust social protection. These call for systemic solutions featuring institutional innovation, resource consolidation, and capability enhancement. Building on Zhejiang's experience as a common prosperity demonstration zone, the article constructs an integrated framework centered on four pillars: industrial empowerment, education upgrading, social security reinforcement, and digital coordination. It further offers concrete policy proposals involving the cultivation of localized industries, vocational skill training, enhanced safety nets, and the adoption of digital tools. The study thus offers both theoretical insights and practical paradigms for tackling the challenge of raising incomes in low-income rural areas.展开更多
Alzheimer’s disease(AD)is a complex,progressive neurodegenerative disorder and the leading cause of dementia worldwide.It is characterized by the accumulation of extracellular amyloid-beta(Aβ)plaques and intracellul...Alzheimer’s disease(AD)is a complex,progressive neurodegenerative disorder and the leading cause of dementia worldwide.It is characterized by the accumulation of extracellular amyloid-beta(Aβ)plaques and intracellular tau neurofibrillary tangles,leading to synaptic dysfunction,neuronal loss,and cognitive decline.These pathological changes can begin decades before clinical symptoms emerge,highlighting the critical need for early,accessible,and accurate diagnostic tools.展开更多
For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies ...For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies bionic analytical framework based on the partial differential equation-ordinary differential equation(PDE-ODE)approach.Specifically,by designing a specialized network communication protocol and employing the spatial continuum method for densely distributed agents,this paper models the tracking errors of densely distributed agents as a PDE equivalent to a human disease transmission model,and that of sparsely distributed agents as several ODEs equivalent to the predator population models.The coupling relationship between the PDE and ODE models is established through boundary conditions of the PDE,thereby forming a PDE-ODE-based tracking error model for the considered MASs.Furthermore,by integrating adaptive neural control scheme with the aforementioned biological models,a“Flexible Neural Network”endowed with adaptive and self-stabilized capabilities is constructed,which acts upon the considered MASs,enabling their practical finite-time deployment.Finally,effectiveness of the developed approach is illustrated through a numerical example.展开更多
This paper presents a robust finite-time visual servo control strategy for the tracking problem of omni-directional mobile manipulators(OMMs)subject to mismatched disturbances.First,the nonlinear kinematic model of vi...This paper presents a robust finite-time visual servo control strategy for the tracking problem of omni-directional mobile manipulators(OMMs)subject to mismatched disturbances.First,the nonlinear kinematic model of visual servoing for OMMs with mismatched disturbances is explicitly presented to solve the whole-body inverse kinematic problem.Second,a sliding mode observer augmented with an integral terminal sliding mode controller is proposed to handle these uncertainties and ensure that the system converges to a small region around the equilibrium point.The boundary layer technique is employed to mitigate the chattering phenomenon.Furthermore,a strict finite-time Lyapunov stability analysis is conducted.An experimental comparison between the proposed algorithm and a traditional position-based visual servo controller is carried out,and the results demonstrate the superiority of the proposed control algorithm.展开更多
The adaptive H_(∞) finite-time boundedness control problem is studied for a set of nonlinear singular Hamiltonian system(NSHS)in this article.Under an appropriate adaptive state feedback,the NSHS can be equivalently ...The adaptive H_(∞) finite-time boundedness control problem is studied for a set of nonlinear singular Hamiltonian system(NSHS)in this article.Under an appropriate adaptive state feedback,the NSHS can be equivalently transformed into a differential-algebraic system.Next,it is proved that the state feedback can be used as an adaptive H_(∞) finite-time boundedness controller of NSHS.Finally,the effectiveness of the controller designed is verified by an illustrative example of a nonlinear singular circuit system.展开更多
The vonoprazan(VPZ)triple therapy regimen for Helicobacter pylori(H.pylori)eradication developed by Han et al employs a scientifically rigorous clinical trial design.This multicenter randomized controlled trial establ...The vonoprazan(VPZ)triple therapy regimen for Helicobacter pylori(H.pylori)eradication developed by Han et al employs a scientifically rigorous clinical trial design.This multicenter randomized controlled trial establishes a standardized treatment framework aimed at improving H.pylori eradication rates,focusing on simplifying treatment regimens,shortening therapy duration,and optimizing therapeutic outcomes.The core of clinical translation lies in improving drug accessibility,establishing multidimensional safety evaluation systems,and optimizing cost-effectiveness.Conducting regional adaptability studies and comprehensive safety assessments is crucial for enhancing VPZ regimen effectiveness in China’s diverse healthcare environments.This study provides important evidence-based support for optimizing H.pylori treatment strategies in China,though further validation of universal applicability for nationwide implementation remains necessary.展开更多
Intercepting high-maneuverability hypersonic targets in near-space environments poses significant challenges due to their extreme speeds and evasive capabilities.To address these challenges,this study presents an inte...Intercepting high-maneuverability hypersonic targets in near-space environments poses significant challenges due to their extreme speeds and evasive capabilities.To address these challenges,this study presents an integrated approach that combines a Three-Dimensional Finite-Time Optimal Cooperative Guidance Law(FTOC)with an Information Fusion Anti-saturation Predefined-time Observer(IFAPO).The proposed FTOC guidance law employs a nonlinear,non-quadratic finite-time optimal control strategy designed for rapid convergence within the limited timeframes of near-space interceptions,avoiding the need for remaining flight time estimation or linear decoupling inherent in traditional methods.To complement the guidance strategy,the IFAPO leverages multi-source information fusion theory and incorporates anti-saturation mechanisms to enhance target maneuver estimation.This method ensures accurate and real-time prediction of target acceleration while maintaining predefined convergence performance,even under complex interception conditions.By integrating the FTOC guidance law and IFAPO,the approach optimizes cooperative missile positioning,improves interception success rates,and minimizes fuel consumption,addressing practical constraints in military applications.Simulation results and comparative analyses confirm the effectiveness of the integrated approach,demonstrating its capability to achieve cooperative interception of highly maneuvering targets with enhanced efficiency and reduced economic costs,aligning with realistic combat scenarios.展开更多
This paper investigates the problem of fuzzy adaptive finite-time inverse optimal control for active suspension systems(ASSs).The fuzzy logic systems(FLSs)are utilized to learn the unknown non-linear dynamics and an a...This paper investigates the problem of fuzzy adaptive finite-time inverse optimal control for active suspension systems(ASSs).The fuzzy logic systems(FLSs)are utilized to learn the unknown non-linear dynamics and an auxiliary system is established.Based on the finite-time stability theory and inverse optimal theory,a fuzzy adaptive inverse finite-time inverse optimal control method is proposed.It is proven that the formulated control approach guarantees the stability of the controlled systems,while ensuring that errors converge to a small neighborhood of zero within finite time.Moreover,the optimized control performance can be achieved.Eventually,the simulation results demonstrate the effectiveness of the proposed fuzzy adaptive finite-time inverse optimal control scheme.展开更多
Language policies are of great significance to a nation’s stability,unity,and development.Uzbekistan’s language policies have reflected the political,economic,and cultural dynamics of different periods throughout hi...Language policies are of great significance to a nation’s stability,unity,and development.Uzbekistan’s language policies have reflected the political,economic,and cultural dynamics of different periods throughout historical changes,influencing social structures and ethnic relations.This paper summarizes the characteristics of Uzbekistan’s language policies in different eras:During the Tsarist Russian period,the Russification of language policies hindered the development of local languages;in the Soviet era,policies adopted a dual approach,promoting both Russian and prioritizing ethnic languages;after independence,Uzbekistan established Uzbek as the state language and emphasized foreign language education.The current language policy in Uzbekistan presents a complex landscape:While emphasizing the dominant role of the national language helps preserve its heritage,it may easily spark ethnic and political tensions;promoting pluralism and inclusivity brings benefits but faces challenges in balancing language statuses,resource allocation,management,and communication;modernization efforts encounter difficulties in standardizing dialects and foreign loanwords;and in international exchanges,there is a need to balance relations with global lingua francas.In conclusion,Uzbekistan’s language policies have undergone unique transformations and face numerous challenges.In-depth research is crucial for improving the country’s policies and enhancing China-Uzbekistan cooperation.Proactive measures are needed to address these challenges,ensuring the sustainability of language policies and fostering greater national prosperity.展开更多
Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds tha...Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds that the low-altitude economy can effectively promote the development of high-end and diversified tourism in Zhejiang by innovating tourism formats,optimizing resource allocation,and enhancing tourist experiences.Besides,it analyzes the current development status of the low-altitude economy in Zhejiang and its potential for integration with tourism,revealing specific enabling pathways for tourism transformation,including low-altitude sightseeing,aviation tourism,and low-altitude sports.Finally,it proposes policy recommendations such as strengthening policy support,enhancing infrastructure development,and cultivating market entities.The findings aim to provide theoretical references and practical guidance for the high-quality development of tourism in Zhejiang Province.展开更多
The demand for Chinese-Western medicine collaboration has grown significantly,but current integration methods have substantial limitations.This article analyzes core issues in developing and implementing synergistic C...The demand for Chinese-Western medicine collaboration has grown significantly,but current integration methods have substantial limitations.This article analyzes core issues in developing and implementing synergistic Chinese-Western medicine clinical treatment strategies and explores the transformation from traditional integration to genuine synergistic models.We analyzed methodological obstacles in synergistic strategy development through literature review and theoretical analysis,and explored applications of intelligent technology in strategy development.Four core challenges were identified:(1)Treatment timing coordination difficulties caused by different decision-making approaches,with Chinese medicine using syndrome-based assessments and Western medicine relying on standardized measurements;(2)Treatment selection complexities when integrating different types of evidence,lacking frameworks for evaluating and combining diverse evidence sources;(3)Obstacles in incorporating patient preferences systematically,with inadequate assessment methods and unclear integration mechanisms;(4)Implementation barriers in translating synergistic strategies into clinical practice,requiring changes in organizational structures,workflows,and evaluation systems.Large language models(LLMs)and other intelligent technologies offer technical support for addressing these methodological challenges.This article examines current challenges in developing synergistic Chinese-Western medicine clinical strategies,analyzing the shift from traditional integration toward synergistic approaches and identifying four core methodological obstacles.Exploring intelligent technology applications provides insights to inform future research directions and clinical practice development in integrated healthcare delivery.展开更多
Currently,we have entered the era of artificial intelligence(AI).The rapid development and wide application of AI technology have exerted a profound impact on all fields of society.Against this backdrop,this paper con...Currently,we have entered the era of artificial intelligence(AI).The rapid development and wide application of AI technology have exerted a profound impact on all fields of society.Against this backdrop,this paper conducts an in-depth analysis focusing on general education in AI.First,it expounds the necessity of AI general education in cultivating the core literacy of vocational college students.Then,it puts forward effective implementation paths for such general education.The purpose is to provide valuable references for promoting the reform and innovative development of vocational education.展开更多
Oncology covers a wide range of knowledge and is more difficult compared to other clinical disciplines.Therefore,it is crucial to seek an efficient teaching method for oncology education.In recent years,China’s inter...Oncology covers a wide range of knowledge and is more difficult compared to other clinical disciplines.Therefore,it is crucial to seek an efficient teaching method for oncology education.In recent years,China’s internet technology has achieved rapid development.Massive Open Online Course(MOOC),a blended learning approach based on internet technology,has strong applicability to medical education.It can not only improve teaching quality but also promote further reform of the discipline.Based on this,our study searched for relevant research at home and abroad and reviewed the implementation path of integrating MOOC and blended learning in oncology education.This provides a theoretical foundation for the innovation of oncology teaching models,improves the level of oncology teaching,and lays a solid foundation for talent reserves in oncology departments.展开更多
In the wave of higher education internationalization,college students’career education is faced with problems such as inadequate integration of international elements in teaching content,insufficient depth of interna...In the wave of higher education internationalization,college students’career education is faced with problems such as inadequate integration of international elements in teaching content,insufficient depth of international cooperation in practical links,lack of international professional experience among the teaching staff,and insufficient emphasis on the cultivation of multicultural adaptability in the education model.Based on this,this paper deeply explores the new requirements put forward by internationalization for college students’career education and its diversified implementation paths from the perspective of higher education internationalization.It aims to build a comprehensive and multi-level career education system and improve students’international competitiveness through strategies such as constructing an internationalized curriculum system,expanding international cooperation practice projects,strengthening international exchanges and training for teachers,and integrating multicultural education.展开更多
The efficient implementation of the Advanced Encryption Standard(AES)is crucial for network data security.This paper presents novel hardware implementations of the AES S-box,a core component,using tower field represen...The efficient implementation of the Advanced Encryption Standard(AES)is crucial for network data security.This paper presents novel hardware implementations of the AES S-box,a core component,using tower field representations and Boolean Satisfiability(SAT)solvers.Our research makes several significant contri-butions to the field.Firstly,we have optimized the GF(24)inversion,achieving a remarkable 31.35%area reduction(15.33 GE)compared to the best known implementations.Secondly,we have enhanced multiplication implementa-tions for transformation matrices using a SAT-method based on local solutions.This approach has yielded notable improvements,such as a 22.22%reduction in area(42.00 GE)for the top transformation matrix in GF((24)2)-type S-box implementation.Furthermore,we have proposed new implementations of GF(((22)2)2)-type and GF((24)2)-type S-boxes,with the GF(((22)2)2)-type demonstrating superior performance.This implementation offers two variants:a small area variant that sets new area records,and a fast variant that establishes new benchmarks in Area-Execution-Time(AET)and energy consumption.Our approach significantly improves upon existing S-box implementations,offering advancements in area,speed,and energy consumption.These optimizations contribute to more efficient and secure AES implementations,potentially enhancing various cryptographic applications in the field of network security.展开更多
Objective:The World Health Organization recommends annual preventive chemotherapy with a single dose of praziquantel at≥75%treatment coverage,but as of 2021,the national coverage rate in Nigeria among children falls ...Objective:The World Health Organization recommends annual preventive chemotherapy with a single dose of praziquantel at≥75%treatment coverage,but as of 2021,the national coverage rate in Nigeria among children falls below 10%.This qualitative study sought to explore the barriers and facilitators to implementing large-scale praziquantel mass drug administration(MDA)programs for school-aged children in Nigeria to delineate tools and strategies that could improve the scaling-up and effectiveness of school-based praziquantel MDA programs.Methods:An exploratory qualitative study was conducted with stakeholders with experience in MDAs involving praziquantel or related preventive chemotherapy drugs in Nigeria.Through snowball sampling,30 stakeholders with experience in praziquantel school-based MDA in Nigeria were interviewed.An inductive approach was used to generate broad themes based on the barriers and facilitators identified by the key informants.Results:A total of 45 barriers and 36 facilitators were identified and grouped inductively into eight themes:funding and resources,design and composition of praziquantel tablets,knowledge and awareness mobilization,government,nongovernmental organization,and school engagement,data management,logistics,training,and security.Conclusion:This qualitative study reveals a wide range of barriers and facilitators in the MDA of praziquantel in Nigeria and uncovered critical points along the implementation pathway based on the locus of the barriers and facilitators identified.Collaboration with national,international,and non-profit organizations,and drug education through promotional materials,were the most frequently mentioned facilitators of the MDA program.In addition,insufficient program funding,and the complexity of the supply chain were the most cited barriers.展开更多
The Lagrangian integral time scale(LITS)is a crucial characteristic for investigating the changes in fluid dynamics induced by the chaotic nature,and the finitetime Lyapunov exponent(FTLE)serves as a key measure in th...The Lagrangian integral time scale(LITS)is a crucial characteristic for investigating the changes in fluid dynamics induced by the chaotic nature,and the finitetime Lyapunov exponent(FTLE)serves as a key measure in the analysis of chaos.In this study,a new LITS model with an explicit theoretical basis and broad applicability is proposed based on the FTLE,along with a verification and evaluation criterion grounded in the Lagrangian velocity correlation coefficient.The model is used to cavitating the flow around a Clark-Y hydrofoil,and the LITS is investigated.It leads to the determination of model constants applicable to cavitating flow.The model is evaluated by the Lagrangian velocity correlation coefficient in comparison with other solution methods.All the results show that the LITS model can offer a new perspective and a new approach for studying the changes in fluid dynamics from a Lagrangian viewpoint.展开更多
In the context of industry-education integration,computer science competitions face new opportunities and challenges.Taking College S as an example,this paper analyses the current development status and difficulties f...In the context of industry-education integration,computer science competitions face new opportunities and challenges.Taking College S as an example,this paper analyses the current development status and difficulties faced by discipline competition in this area.On this basis,in combination with the requirements of industry-education integration,four aspects of implementation paths are proposed:improving competition management mechanisms,optimizing competition organization models,innovating competition content design,and enhancing the transformation of competition results.This paper also constructs a computer science discipline competition system in three dimensions:cultivating students’innovative abilities,enhancing teachers’practical teaching levels,and deepening school-enterprise cooperation.The aim is to provide a reference for the conduct of computer science discipline competitions in higher education institutions and to promote the reform and innovation of talent cultivation models.展开更多
Background:Community-based first responders face high levels of workplace stressors that can pro-foundly impact their physical and mental health.Mindfulness-based interventions have shown promise in decreasing stress ...Background:Community-based first responders face high levels of workplace stressors that can pro-foundly impact their physical and mental health.Mindfulness-based interventions have shown promise in decreasing stress and increasing psychological resilience;however,implementation is difficult due to unpredictability of the job,department culture,and generational preferences.The objective of this qualitative study was to identify and enhance understanding of the specific needs and potential barriers and facilitators for the implementation of mindfulness-based programming for community-based first responders.Methods:A phenomenological qualitative study design was used to gain insights into the lived experiences of first responders and elicit perceptions regarding barriers and facilitators for engaging in mindfulness activities.During virtual semi-structured interviews,eleven career firefighters and emergency medical service(EMS)providers offered feedback relative to worksite mindfulness practices,and the use of a stress reduction smartphone application.The Consolidated Framework for Implementation Research was used to guide the analysis relative to barriers and facilitators of implementation success and sustainability.Results:First responders expressed openness to mindfulness-based interventions and a smartphone app that would provide stress reduction content,however,they were adamant that programming needed to be accessible and easily integrated into their workday.They also reinforced that organizational culture and leadership support for their health and well-being were overarching factors essential for implementation success.Conclusions:First responders were supportive of evidence-based mindfulness practices,optimally developed and/or facilitated by someone with intimate knowledge of their unique work environments and challenges.Organizational culture and leadership support were essential for implementation success and sustainability.展开更多
基金Scientific Research Fund Project of Yunnan Provincial Department of Education(Project No.:2024J2130)。
文摘Objective:To systematically review the current implementation status of nurses’non-pharmacological prescription authority and analyze the barriers encountered during its implementation in China,providing countermeasures and references for promoting the standardized implementation of nurses’non-pharmacological prescription authority.Methods:A secondary analysis of literature was conducted to systematically search for domestic and international literature related to nurses’non-pharmacological prescription authority.Meta-analysis was performed on eligible literature to evaluate the implementation effects.Simultaneously,semi-structured in-depth interviews were conducted with healthcare workers,patients,and policymakers.Content analysis was used to organize the interview data and extract core issues and barriers.Results:A total of 46 international articles were included in the Meta-analysis,which revealed that the implementation of nurses’non-pharmacological prescription authority significantly improved patients’health management outcomes,enhanced healthcare service efficiency,and increased patient satisfaction.Conclusion:The implementation of nurses’non-pharmacological prescription authority has demonstrated significant positive effects.However,China faces multiple barriers in its advancement,necessitating efforts in optimizing policy systems,constructing collaborative models,strengthening professional skills training,and improving social awareness to guide the scientific and rational implementation of nurses’non-pharmacological prescription authority.
文摘Taking the rural low-income population of Zhejiang Province as its subject, this paper examines how to build a sustainable income-growth mechanism and identify feasible implementation paths within the context of the common prosperity strategy. The research identifies key obstacles to income expansion, including an undiversified industrial structure, insufficient human capital, and a lack of robust social protection. These call for systemic solutions featuring institutional innovation, resource consolidation, and capability enhancement. Building on Zhejiang's experience as a common prosperity demonstration zone, the article constructs an integrated framework centered on four pillars: industrial empowerment, education upgrading, social security reinforcement, and digital coordination. It further offers concrete policy proposals involving the cultivation of localized industries, vocational skill training, enhanced safety nets, and the adoption of digital tools. The study thus offers both theoretical insights and practical paradigms for tackling the challenge of raising incomes in low-income rural areas.
文摘Alzheimer’s disease(AD)is a complex,progressive neurodegenerative disorder and the leading cause of dementia worldwide.It is characterized by the accumulation of extracellular amyloid-beta(Aβ)plaques and intracellular tau neurofibrillary tangles,leading to synaptic dysfunction,neuronal loss,and cognitive decline.These pathological changes can begin decades before clinical symptoms emerge,highlighting the critical need for early,accessible,and accurate diagnostic tools.
基金The National Key R&D Program of China(2021ZD0201300)the National Natural Science Foundation of China(624B2058,U1913602 and 61936004)+1 种基金the Innovation Group Project of the National Natural Science Foundation of China(61821003)the 111 Project on Computational Intelligence and Intelligent Control(B18024).
文摘For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies bionic analytical framework based on the partial differential equation-ordinary differential equation(PDE-ODE)approach.Specifically,by designing a specialized network communication protocol and employing the spatial continuum method for densely distributed agents,this paper models the tracking errors of densely distributed agents as a PDE equivalent to a human disease transmission model,and that of sparsely distributed agents as several ODEs equivalent to the predator population models.The coupling relationship between the PDE and ODE models is established through boundary conditions of the PDE,thereby forming a PDE-ODE-based tracking error model for the considered MASs.Furthermore,by integrating adaptive neural control scheme with the aforementioned biological models,a“Flexible Neural Network”endowed with adaptive and self-stabilized capabilities is constructed,which acts upon the considered MASs,enabling their practical finite-time deployment.Finally,effectiveness of the developed approach is illustrated through a numerical example.
基金supported by the Artificial Intelligence Innovation and Development Special Fund of Shanghai(No.2019RGZN01041)the National Natural Science Foundation of China(No.92048205).
文摘This paper presents a robust finite-time visual servo control strategy for the tracking problem of omni-directional mobile manipulators(OMMs)subject to mismatched disturbances.First,the nonlinear kinematic model of visual servoing for OMMs with mismatched disturbances is explicitly presented to solve the whole-body inverse kinematic problem.Second,a sliding mode observer augmented with an integral terminal sliding mode controller is proposed to handle these uncertainties and ensure that the system converges to a small region around the equilibrium point.The boundary layer technique is employed to mitigate the chattering phenomenon.Furthermore,a strict finite-time Lyapunov stability analysis is conducted.An experimental comparison between the proposed algorithm and a traditional position-based visual servo controller is carried out,and the results demonstrate the superiority of the proposed control algorithm.
基金supported by the National Nature Science Foundation of China (61877028, 61773015).
文摘The adaptive H_(∞) finite-time boundedness control problem is studied for a set of nonlinear singular Hamiltonian system(NSHS)in this article.Under an appropriate adaptive state feedback,the NSHS can be equivalently transformed into a differential-algebraic system.Next,it is proved that the state feedback can be used as an adaptive H_(∞) finite-time boundedness controller of NSHS.Finally,the effectiveness of the controller designed is verified by an illustrative example of a nonlinear singular circuit system.
文摘The vonoprazan(VPZ)triple therapy regimen for Helicobacter pylori(H.pylori)eradication developed by Han et al employs a scientifically rigorous clinical trial design.This multicenter randomized controlled trial establishes a standardized treatment framework aimed at improving H.pylori eradication rates,focusing on simplifying treatment regimens,shortening therapy duration,and optimizing therapeutic outcomes.The core of clinical translation lies in improving drug accessibility,establishing multidimensional safety evaluation systems,and optimizing cost-effectiveness.Conducting regional adaptability studies and comprehensive safety assessments is crucial for enhancing VPZ regimen effectiveness in China’s diverse healthcare environments.This study provides important evidence-based support for optimizing H.pylori treatment strategies in China,though further validation of universal applicability for nationwide implementation remains necessary.
基金supported by the National Natural Science Foundation of China(Grant No.61773142).
文摘Intercepting high-maneuverability hypersonic targets in near-space environments poses significant challenges due to their extreme speeds and evasive capabilities.To address these challenges,this study presents an integrated approach that combines a Three-Dimensional Finite-Time Optimal Cooperative Guidance Law(FTOC)with an Information Fusion Anti-saturation Predefined-time Observer(IFAPO).The proposed FTOC guidance law employs a nonlinear,non-quadratic finite-time optimal control strategy designed for rapid convergence within the limited timeframes of near-space interceptions,avoiding the need for remaining flight time estimation or linear decoupling inherent in traditional methods.To complement the guidance strategy,the IFAPO leverages multi-source information fusion theory and incorporates anti-saturation mechanisms to enhance target maneuver estimation.This method ensures accurate and real-time prediction of target acceleration while maintaining predefined convergence performance,even under complex interception conditions.By integrating the FTOC guidance law and IFAPO,the approach optimizes cooperative missile positioning,improves interception success rates,and minimizes fuel consumption,addressing practical constraints in military applications.Simulation results and comparative analyses confirm the effectiveness of the integrated approach,demonstrating its capability to achieve cooperative interception of highly maneuvering targets with enhanced efficiency and reduced economic costs,aligning with realistic combat scenarios.
基金supported by the National Natural Science Foundation of China under 62173172。
文摘This paper investigates the problem of fuzzy adaptive finite-time inverse optimal control for active suspension systems(ASSs).The fuzzy logic systems(FLSs)are utilized to learn the unknown non-linear dynamics and an auxiliary system is established.Based on the finite-time stability theory and inverse optimal theory,a fuzzy adaptive inverse finite-time inverse optimal control method is proposed.It is proven that the formulated control approach guarantees the stability of the controlled systems,while ensuring that errors converge to a small neighborhood of zero within finite time.Moreover,the optimized control performance can be achieved.Eventually,the simulation results demonstrate the effectiveness of the proposed fuzzy adaptive finite-time inverse optimal control scheme.
基金the 2023 Open Project of the Kazakhstan Research Center at YiIi Normal University,Study on National Language Education Policy in Kazakhstan Under the Belt and Road Initiative(No.2023HSKSTYJYB007).
文摘Language policies are of great significance to a nation’s stability,unity,and development.Uzbekistan’s language policies have reflected the political,economic,and cultural dynamics of different periods throughout historical changes,influencing social structures and ethnic relations.This paper summarizes the characteristics of Uzbekistan’s language policies in different eras:During the Tsarist Russian period,the Russification of language policies hindered the development of local languages;in the Soviet era,policies adopted a dual approach,promoting both Russian and prioritizing ethnic languages;after independence,Uzbekistan established Uzbek as the state language and emphasized foreign language education.The current language policy in Uzbekistan presents a complex landscape:While emphasizing the dominant role of the national language helps preserve its heritage,it may easily spark ethnic and political tensions;promoting pluralism and inclusivity brings benefits but faces challenges in balancing language statuses,resource allocation,management,and communication;modernization efforts encounter difficulties in standardizing dialects and foreign loanwords;and in international exchanges,there is a need to balance relations with global lingua francas.In conclusion,Uzbekistan’s language policies have undergone unique transformations and face numerous challenges.In-depth research is crucial for improving the country’s policies and enhancing China-Uzbekistan cooperation.Proactive measures are needed to address these challenges,ensuring the sustainability of language policies and fostering greater national prosperity.
文摘Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds that the low-altitude economy can effectively promote the development of high-end and diversified tourism in Zhejiang by innovating tourism formats,optimizing resource allocation,and enhancing tourist experiences.Besides,it analyzes the current development status of the low-altitude economy in Zhejiang and its potential for integration with tourism,revealing specific enabling pathways for tourism transformation,including low-altitude sightseeing,aviation tourism,and low-altitude sports.Finally,it proposes policy recommendations such as strengthening policy support,enhancing infrastructure development,and cultivating market entities.The findings aim to provide theoretical references and practical guidance for the high-quality development of tourism in Zhejiang Province.
基金supported by the National Natural Science Foundation of China(No.82204931).
文摘The demand for Chinese-Western medicine collaboration has grown significantly,but current integration methods have substantial limitations.This article analyzes core issues in developing and implementing synergistic Chinese-Western medicine clinical treatment strategies and explores the transformation from traditional integration to genuine synergistic models.We analyzed methodological obstacles in synergistic strategy development through literature review and theoretical analysis,and explored applications of intelligent technology in strategy development.Four core challenges were identified:(1)Treatment timing coordination difficulties caused by different decision-making approaches,with Chinese medicine using syndrome-based assessments and Western medicine relying on standardized measurements;(2)Treatment selection complexities when integrating different types of evidence,lacking frameworks for evaluating and combining diverse evidence sources;(3)Obstacles in incorporating patient preferences systematically,with inadequate assessment methods and unclear integration mechanisms;(4)Implementation barriers in translating synergistic strategies into clinical practice,requiring changes in organizational structures,workflows,and evaluation systems.Large language models(LLMs)and other intelligent technologies offer technical support for addressing these methodological challenges.This article examines current challenges in developing synergistic Chinese-Western medicine clinical strategies,analyzing the shift from traditional integration toward synergistic approaches and identifying four core methodological obstacles.Exploring intelligent technology applications provides insights to inform future research directions and clinical practice development in integrated healthcare delivery.
文摘Currently,we have entered the era of artificial intelligence(AI).The rapid development and wide application of AI technology have exerted a profound impact on all fields of society.Against this backdrop,this paper conducts an in-depth analysis focusing on general education in AI.First,it expounds the necessity of AI general education in cultivating the core literacy of vocational college students.Then,it puts forward effective implementation paths for such general education.The purpose is to provide valuable references for promoting the reform and innovative development of vocational education.
基金Mechanism of Nanotechnology-driven Polyphyllin I in Sensitizing PD-1 Monoclonal Antibody in Breast Cancer(82204922)Nanotechnology-driven Polyphyllin I Affects Mitochondrial Homeostasis via Cuproptosis and Its Mechanism in Breast Cancer Treatment(ZZ18-YQ-022)。
文摘Oncology covers a wide range of knowledge and is more difficult compared to other clinical disciplines.Therefore,it is crucial to seek an efficient teaching method for oncology education.In recent years,China’s internet technology has achieved rapid development.Massive Open Online Course(MOOC),a blended learning approach based on internet technology,has strong applicability to medical education.It can not only improve teaching quality but also promote further reform of the discipline.Based on this,our study searched for relevant research at home and abroad and reviewed the implementation path of integrating MOOC and blended learning in oncology education.This provides a theoretical foundation for the innovation of oncology teaching models,improves the level of oncology teaching,and lays a solid foundation for talent reserves in oncology departments.
文摘In the wave of higher education internationalization,college students’career education is faced with problems such as inadequate integration of international elements in teaching content,insufficient depth of international cooperation in practical links,lack of international professional experience among the teaching staff,and insufficient emphasis on the cultivation of multicultural adaptability in the education model.Based on this,this paper deeply explores the new requirements put forward by internationalization for college students’career education and its diversified implementation paths from the perspective of higher education internationalization.It aims to build a comprehensive and multi-level career education system and improve students’international competitiveness through strategies such as constructing an internationalized curriculum system,expanding international cooperation practice projects,strengthening international exchanges and training for teachers,and integrating multicultural education.
基金supported in part by the National Natural Science Foundation of China(No.62162016)in part by the Innovation Project of Guangxi Graduate Education(Nos.YCBZ2023132 and YCSW2023304).
文摘The efficient implementation of the Advanced Encryption Standard(AES)is crucial for network data security.This paper presents novel hardware implementations of the AES S-box,a core component,using tower field representations and Boolean Satisfiability(SAT)solvers.Our research makes several significant contri-butions to the field.Firstly,we have optimized the GF(24)inversion,achieving a remarkable 31.35%area reduction(15.33 GE)compared to the best known implementations.Secondly,we have enhanced multiplication implementa-tions for transformation matrices using a SAT-method based on local solutions.This approach has yielded notable improvements,such as a 22.22%reduction in area(42.00 GE)for the top transformation matrix in GF((24)2)-type S-box implementation.Furthermore,we have proposed new implementations of GF(((22)2)2)-type and GF((24)2)-type S-boxes,with the GF(((22)2)2)-type demonstrating superior performance.This implementation offers two variants:a small area variant that sets new area records,and a fast variant that establishes new benchmarks in Area-Execution-Time(AET)and energy consumption.Our approach significantly improves upon existing S-box implementations,offering advancements in area,speed,and energy consumption.These optimizations contribute to more efficient and secure AES implementations,potentially enhancing various cryptographic applications in the field of network security.
基金the Flourish Collective,a Cluster of Scholarly Prominence at the University of Toronto,Scarborough。
文摘Objective:The World Health Organization recommends annual preventive chemotherapy with a single dose of praziquantel at≥75%treatment coverage,but as of 2021,the national coverage rate in Nigeria among children falls below 10%.This qualitative study sought to explore the barriers and facilitators to implementing large-scale praziquantel mass drug administration(MDA)programs for school-aged children in Nigeria to delineate tools and strategies that could improve the scaling-up and effectiveness of school-based praziquantel MDA programs.Methods:An exploratory qualitative study was conducted with stakeholders with experience in MDAs involving praziquantel or related preventive chemotherapy drugs in Nigeria.Through snowball sampling,30 stakeholders with experience in praziquantel school-based MDA in Nigeria were interviewed.An inductive approach was used to generate broad themes based on the barriers and facilitators identified by the key informants.Results:A total of 45 barriers and 36 facilitators were identified and grouped inductively into eight themes:funding and resources,design and composition of praziquantel tablets,knowledge and awareness mobilization,government,nongovernmental organization,and school engagement,data management,logistics,training,and security.Conclusion:This qualitative study reveals a wide range of barriers and facilitators in the MDA of praziquantel in Nigeria and uncovered critical points along the implementation pathway based on the locus of the barriers and facilitators identified.Collaboration with national,international,and non-profit organizations,and drug education through promotional materials,were the most frequently mentioned facilitators of the MDA program.In addition,insufficient program funding,and the complexity of the supply chain were the most cited barriers.
基金Project supported by the Key Project of the National Natural Science Foundation of China(No.52336001)the Natural Science Foundation of Zhejiang Province of China(No.LR20E090001)。
文摘The Lagrangian integral time scale(LITS)is a crucial characteristic for investigating the changes in fluid dynamics induced by the chaotic nature,and the finitetime Lyapunov exponent(FTLE)serves as a key measure in the analysis of chaos.In this study,a new LITS model with an explicit theoretical basis and broad applicability is proposed based on the FTLE,along with a verification and evaluation criterion grounded in the Lagrangian velocity correlation coefficient.The model is used to cavitating the flow around a Clark-Y hydrofoil,and the LITS is investigated.It leads to the determination of model constants applicable to cavitating flow.The model is evaluated by the Lagrangian velocity correlation coefficient in comparison with other solution methods.All the results show that the LITS model can offer a new perspective and a new approach for studying the changes in fluid dynamics from a Lagrangian viewpoint.
基金supported by Sanya Aviation&Tourism College,Project number:SATC2023JG-09.
文摘In the context of industry-education integration,computer science competitions face new opportunities and challenges.Taking College S as an example,this paper analyses the current development status and difficulties faced by discipline competition in this area.On this basis,in combination with the requirements of industry-education integration,four aspects of implementation paths are proposed:improving competition management mechanisms,optimizing competition organization models,innovating competition content design,and enhancing the transformation of competition results.This paper also constructs a computer science discipline competition system in three dimensions:cultivating students’innovative abilities,enhancing teachers’practical teaching levels,and deepening school-enterprise cooperation.The aim is to provide a reference for the conduct of computer science discipline competitions in higher education institutions and to promote the reform and innovation of talent cultivation models.
文摘Background:Community-based first responders face high levels of workplace stressors that can pro-foundly impact their physical and mental health.Mindfulness-based interventions have shown promise in decreasing stress and increasing psychological resilience;however,implementation is difficult due to unpredictability of the job,department culture,and generational preferences.The objective of this qualitative study was to identify and enhance understanding of the specific needs and potential barriers and facilitators for the implementation of mindfulness-based programming for community-based first responders.Methods:A phenomenological qualitative study design was used to gain insights into the lived experiences of first responders and elicit perceptions regarding barriers and facilitators for engaging in mindfulness activities.During virtual semi-structured interviews,eleven career firefighters and emergency medical service(EMS)providers offered feedback relative to worksite mindfulness practices,and the use of a stress reduction smartphone application.The Consolidated Framework for Implementation Research was used to guide the analysis relative to barriers and facilitators of implementation success and sustainability.Results:First responders expressed openness to mindfulness-based interventions and a smartphone app that would provide stress reduction content,however,they were adamant that programming needed to be accessible and easily integrated into their workday.They also reinforced that organizational culture and leadership support for their health and well-being were overarching factors essential for implementation success.Conclusions:First responders were supportive of evidence-based mindfulness practices,optimally developed and/or facilitated by someone with intimate knowledge of their unique work environments and challenges.Organizational culture and leadership support were essential for implementation success and sustainability.
