Several parameters for predicting survival in patients with colorectal cancer have been identified, including the performance status, age, gender and tumor-nodemetastasis(TNM) stage. Although the TNM stage is importan...Several parameters for predicting survival in patients with colorectal cancer have been identified, including the performance status, age, gender and tumor-nodemetastasis(TNM) stage. Although the TNM stage is important and useful for predicting the prognosis and determining the appropriate treatment, it is well known that the survival time varies widely, even in patients with the same stage of disease. Therefore, the identification of new parameters capable of more precisely predicting patient survival is needed to help select the optimal treatment, especially in patients in the advanced stage of disease. Although the TNM stage reflects the tumor characteristics, cancer progression and survival are not determined solely based on the local characteristics of the tumor, but also the host systemic immune/inflammatory response. Therefore, using a combination of parameters that reflect both tumor characteristics and the host systemic inflammatory status is thought to be important for accurately predicting patient survival.展开更多
Reference values of erythrocyte sedimentation rate(ESR)are the key to interpret ESR blood test in clinic.The common local reference ESR values are more accuracy in blood test that are established with natural geograph...Reference values of erythrocyte sedimentation rate(ESR)are the key to interpret ESR blood test in clinic.The common local reference ESR values are more accuracy in blood test that are established with natural geographical factors by using the multiple linear regression(MLR)model and the artificial neural network(ANN).These knowledge-based methods have limitations since the knowledge domains of ESR and natural geographical factors are limited.This paper presents a new cases-depended model to establish reference ESR values with natural geographical factors and location using case-based reasoning(CBR)since knowledge domain of ESR and geographical factors is weak.Overall 224 local normal ESR values of China that calculated from 13623 samples were obtained,and the corresponding natural geographical factors and location that include altitude,sunshine hours,relative humidity,temperature,precipitation,annual temperature range and annual average wind speed were obtained from the National Geomatics Center of China.CBR was used to predict the unseen local reference ESR values with cases.The average absolute deviation(AAD),mean square error(MSE),prediction accuracy(PA),and Pearson correlation coefficient(r)between the observed and estimated data of proposed model is 33.07%,9.02,66.93% and 0.78,which are better than those of ANN and MLR model.The results show that the proposed model provides higher prediction accuracy than those of the artificial neural network and multiple linear regression models.The predicted values are very close to the observed values.Model results show significant agreement of cases data.Consequently,the model is used to predict the unseen local reference ESR with natural geographical factors and location.In spatial,the highest ESR reference areas are distributed in the southern-western district of China that includes Sichuan,Chongqing,Guangxi and Guizhou provinces,and the reference ESR values are greater than 23 mm/60 min.The higher ESR reference values are distributed in the middle part and northern-eastern of China which include Hubei,Henan,Shaanxi,Shanxi,Jilin and Heilongjiang provinces,and the reference ESR values are greater than 18 mm/60min.The lowest ESR reference values are distributed in the northern-western of China that includes Tibet and Xinjiang,and the reference ESR values are lower than 5 mm/60min.展开更多
<strong>Background: </strong><span style="font-family:;" "=""><span style="font-family:Verdana;">Cardiovascular</span><b><i><span style=&...<strong>Background: </strong><span style="font-family:;" "=""><span style="font-family:Verdana;">Cardiovascular</span><b><i><span style="font-family:Verdana;"> </span></i></b><span style="font-family:Verdana;">risk factors play </span></span><span style="font-family:Verdana;">a </span><span style="font-family:;" "=""><span style="font-family:Verdana;">major role in cardiovascular disease burden worldwide. The prevalence is known to be in the increase especially in the developing countries. There is need for timely community based studies in order to keep tab with the current scope. It is against this background that we embarked on this cross-sectional community based study of the prevalence of selected cardiovascular risk factors in semi-urban community in Abakaliki Southeastern part of Nigeria in October 2016. </span><b><span style="font-family:Verdana;">Method:</span><i><span style="font-family:Verdana;"> </span></i></b><span style="font-family:Verdana;">The consecutive consenting persons of 18</span></span><span style="font-family:Verdana;"> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">years and above were screened for selected cardiovascular risk factors in October 2016. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">A total of 1074 adults were seen (males-567, females-507) with age range of 18</span></span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">- 80</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">years and mean age of 35.63 ± 12.45</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">years. They were predominantly farmers, petty traders and artisans. The identified CVD risk factors were hypertension 285 (26.4%), alcohol abuse 131</span><span style="font-family:Verdana;"> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">(12.1%), obesity 122 (11.3%), diabetes 97 (9%), family history of stroke 87 (8.1%), smoking 74 (6.9%) and previous stroke 29 (2.7%). </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">The cardiovascular risk factors were quite prevalent with male preponderance of alcohol abuse and smoking.</span></span>展开更多
To date, many efforts have been made to improve the performance of paintable carbon-based （PC-based） perovskite solar cells （PSCs）. Though great progress has been achieved, their power conversion efficiencies are ...To date, many efforts have been made to improve the performance of paintable carbon-based （PC-based） perovskite solar cells （PSCs）. Though great progress has been achieved, their power conversion efficiencies are still relatively low compared with hole-transport-materials-based PSCs. General research on influencing factors of performance in PC-based PSCs is still insufficient. In this work, PC-based PSCs were fabricated in ambient air and four groups of controlled experi- ments were performed in which the PbI2 layers were prepared with or without antisolvent extraction treatment. These four groups of experiments were designed to find out the effect of different influencing factors on PC-based PSCs performance, for example, PbI2 residual, the surface morphology of the perovskite film, the surface roughness of the perovskite film, and the contact status of the perovskite/carbon electrode interface. With a systematic analysis, we demonstrated that the contact status of the perovskite/carbon electrode interface played a vital role in PC-based PSCs, and a fiat, smooth perovskite surface could help to improve this contact status significantly. Besides, on the precondition of a poor contact interface, no PbI2 residual and a good surface morphology only brought limited benefits to the performances of PC-based PSCs.展开更多
Taking a total of 13 areas in Heilongjiang commodity grain base as the research objects,9 indices are selected,which are regional GDP(X1),per capita GDP(X2),total value of tertiary industry(X3),financial revenue(X4),u...Taking a total of 13 areas in Heilongjiang commodity grain base as the research objects,9 indices are selected,which are regional GDP(X1),per capita GDP(X2),total value of tertiary industry(X3),financial revenue(X4),urban fixed assets investment(X5),average salary(X6),gross industrial output value(X7),total output value of farming,forestry,husbandry and fishing(X8),and retail sales of social consumer goods(X9).Based on this,evaluation index system of regional economy is established.According to the 2006-2008 Heilongjiang Statistical Yearbook,average values within 3 years are used as analytical data.Factor Analysis Method is adopted to establish regression model and to carry out comprehensive analysis.Result shows that Heilongjiang commodity grain base has extremely uneven regional economic development in different areas.According to the score order and actual situation,the 13 areas are divided into 4 types.The first and second types are Harbin and Daqing,respectively.The third type is Qiqihaer,Suihua,Mudanjiang and Jiamusi.And the forth type is Jixi,Shuangyashan,Heihe,Yichun,Qitaihe,Hegang and Daxinganling.Suggestions for the development of these areas are put forward.展开更多
Object-based audio coding is the main technique of audio scene coding. It can effectively reconstruct each object trajectory, besides provide sufficient flexibility for personalized audio scene reconstruction. So more...Object-based audio coding is the main technique of audio scene coding. It can effectively reconstruct each object trajectory, besides provide sufficient flexibility for personalized audio scene reconstruction. So more and more attentions have been paid to the object-based audio coding. However, existing object-based techniques have poor sound quality because of low parameter frequency domain resolution. In order to achieve high quality audio object coding, we propose a new coding framework with introducing the non-negative matrix factorization(NMF) method. We extract object parameters with high resolution to improve sound quality, and apply NMF method to parameter coding to reduce the high bitrate caused by high resolution. And the experimental results have shown that the proposed framework can improve the coding quality by 25%, so it can provide a better solution to encode audio scene in a more flexible and higher quality way.展开更多
Focusing on controlling the press-assembly quality of high-precision servo mechanism,an intelligent early warning method based on outlier data detection and linear regression is proposed.Linear regression is used to d...Focusing on controlling the press-assembly quality of high-precision servo mechanism,an intelligent early warning method based on outlier data detection and linear regression is proposed.Linear regression is used to deal with the relationship between assembly quality and press-assembly process,then the mathematical model of displacement-force in press-assembly process is established and a qualified press-assembly force range is defined for assembly quality control.To preprocess the raw dataset of displacement-force in the press-assembly process,an improved local outlier factor based on area density and P weight(LAOPW)is designed to eliminate the outliers which will result in inaccuracy of the mathematical model.A weighted distance based on information entropy is used to measure distance,and the reachable distance is replaced with P weight.Experiments show that the detection efficiency of the algorithm is improved by 5.6 ms compared with the traditional local outlier factor(LOF)algorithm,and the detection accuracy is improved by about 2%compared with the local outlier factor based on area density(LAOF)algorithm.The application of LAOPW algorithm and the linear regression model shows that it can effectively carry out intelligent early warning of press-assembly quality of high precision servo mechanism.展开更多
目的:探究乳腺癌病人婚姻质量的影响因素。方法:检索Cochrane Library、PubMed、EMbase、Web of Science、中国生物医学文献数据库、中国知网、万方数据库和维普数据库中关于乳腺癌病人婚姻质量的队列研究、病例对照研究和横断面研究。...目的:探究乳腺癌病人婚姻质量的影响因素。方法:检索Cochrane Library、PubMed、EMbase、Web of Science、中国生物医学文献数据库、中国知网、万方数据库和维普数据库中关于乳腺癌病人婚姻质量的队列研究、病例对照研究和横断面研究。采用Stata14.0软件对数据进行Meta分析。结果:共纳入15篇文献,总样本量为3 906例。乳腺癌病人婚姻质量的影响因素包括文化程度[OR=1.67,95%CI(1.00,2.80),P=0.05]、家庭经济收入[OR=12.21,95%CI(9.20,16.21),P<0.001]、婚姻状况[OR=2.10,95%CI(1.41,3.14),P<0.001]、医疗费用来源[OR=2.65,95%CI(2.34,3.00),P<0.001]、承担家务情况[OR=2.14,95%CI(1.67,4.29),P=0.032]、病程[OR=3.12,95%CI(2.08,4.70),P<0.001]、婚姻满意度[OR=3.55,95%CI(3.08,4.09),P<0.001]、性生活体验[OR=2.82,95%CI(2.40,3.33),P<0.001]、社会支持[OR=1.74,95%CI(1.35,2.23),P=0.032]。结论:乳腺癌严重影响女性病人的婚姻质量,护理人员应提高对乳腺癌病人婚姻质量的认识水平和重视程度,制订全程、精细和个性化的心理干预措施,以预防乳腺癌病人婚姻焦虑。展开更多
目的:系统评价髋部骨折病人住院时间延长发生率及影响因素。方法:计算机检索中国知网、万方数据库、中国生物医学文献数据库、PubMed、Cochrane Library、Web of Science、EMbase中关于髋部骨折病人住院时间延长发生率及影响因素的病例...目的:系统评价髋部骨折病人住院时间延长发生率及影响因素。方法:计算机检索中国知网、万方数据库、中国生物医学文献数据库、PubMed、Cochrane Library、Web of Science、EMbase中关于髋部骨折病人住院时间延长发生率及影响因素的病例对照研究和队列研究,检索时限为建库至2025年7月2日。由2名研究者独立进行文献的筛选、资料提取和质量评价。采用RevMan 5.3和Stata 18.0软件进行Meta分析。结果:纳入14篇文献,涉及105 874例髋部骨折病人。Meta分析结果显示,髋部骨折病人住院时间延长的发生率为31%[95%CI(0.23,0.38)]。美国麻醉医师学会分级、术前等待时间、低蛋白血症、肺部感染、性别、脑血管疾病、高血压、糖尿病、心力衰竭、贫血为髋部骨折病人住院时间延长的影响因素(P<0.001)。结论:临床医护人员可参考本研究结果中的影响因素开展针对性的干预措施,以减少髋部骨折病人发生住院时间延长。展开更多
文摘Several parameters for predicting survival in patients with colorectal cancer have been identified, including the performance status, age, gender and tumor-nodemetastasis(TNM) stage. Although the TNM stage is important and useful for predicting the prognosis and determining the appropriate treatment, it is well known that the survival time varies widely, even in patients with the same stage of disease. Therefore, the identification of new parameters capable of more precisely predicting patient survival is needed to help select the optimal treatment, especially in patients in the advanced stage of disease. Although the TNM stage reflects the tumor characteristics, cancer progression and survival are not determined solely based on the local characteristics of the tumor, but also the host systemic immune/inflammatory response. Therefore, using a combination of parameters that reflect both tumor characteristics and the host systemic inflammatory status is thought to be important for accurately predicting patient survival.
基金Under the auspices of National Natural Science Foundation of China(No.40971060)
文摘Reference values of erythrocyte sedimentation rate(ESR)are the key to interpret ESR blood test in clinic.The common local reference ESR values are more accuracy in blood test that are established with natural geographical factors by using the multiple linear regression(MLR)model and the artificial neural network(ANN).These knowledge-based methods have limitations since the knowledge domains of ESR and natural geographical factors are limited.This paper presents a new cases-depended model to establish reference ESR values with natural geographical factors and location using case-based reasoning(CBR)since knowledge domain of ESR and geographical factors is weak.Overall 224 local normal ESR values of China that calculated from 13623 samples were obtained,and the corresponding natural geographical factors and location that include altitude,sunshine hours,relative humidity,temperature,precipitation,annual temperature range and annual average wind speed were obtained from the National Geomatics Center of China.CBR was used to predict the unseen local reference ESR values with cases.The average absolute deviation(AAD),mean square error(MSE),prediction accuracy(PA),and Pearson correlation coefficient(r)between the observed and estimated data of proposed model is 33.07%,9.02,66.93% and 0.78,which are better than those of ANN and MLR model.The results show that the proposed model provides higher prediction accuracy than those of the artificial neural network and multiple linear regression models.The predicted values are very close to the observed values.Model results show significant agreement of cases data.Consequently,the model is used to predict the unseen local reference ESR with natural geographical factors and location.In spatial,the highest ESR reference areas are distributed in the southern-western district of China that includes Sichuan,Chongqing,Guangxi and Guizhou provinces,and the reference ESR values are greater than 23 mm/60 min.The higher ESR reference values are distributed in the middle part and northern-eastern of China which include Hubei,Henan,Shaanxi,Shanxi,Jilin and Heilongjiang provinces,and the reference ESR values are greater than 18 mm/60min.The lowest ESR reference values are distributed in the northern-western of China that includes Tibet and Xinjiang,and the reference ESR values are lower than 5 mm/60min.
文摘<strong>Background: </strong><span style="font-family:;" "=""><span style="font-family:Verdana;">Cardiovascular</span><b><i><span style="font-family:Verdana;"> </span></i></b><span style="font-family:Verdana;">risk factors play </span></span><span style="font-family:Verdana;">a </span><span style="font-family:;" "=""><span style="font-family:Verdana;">major role in cardiovascular disease burden worldwide. The prevalence is known to be in the increase especially in the developing countries. There is need for timely community based studies in order to keep tab with the current scope. It is against this background that we embarked on this cross-sectional community based study of the prevalence of selected cardiovascular risk factors in semi-urban community in Abakaliki Southeastern part of Nigeria in October 2016. </span><b><span style="font-family:Verdana;">Method:</span><i><span style="font-family:Verdana;"> </span></i></b><span style="font-family:Verdana;">The consecutive consenting persons of 18</span></span><span style="font-family:Verdana;"> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">years and above were screened for selected cardiovascular risk factors in October 2016. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">A total of 1074 adults were seen (males-567, females-507) with age range of 18</span></span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">- 80</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">years and mean age of 35.63 ± 12.45</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">years. They were predominantly farmers, petty traders and artisans. The identified CVD risk factors were hypertension 285 (26.4%), alcohol abuse 131</span><span style="font-family:Verdana;"> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">(12.1%), obesity 122 (11.3%), diabetes 97 (9%), family history of stroke 87 (8.1%), smoking 74 (6.9%) and previous stroke 29 (2.7%). </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">The cardiovascular risk factors were quite prevalent with male preponderance of alcohol abuse and smoking.</span></span>
基金Project supported by the National Natural Science Foundation of China(Grant No.51702245)the Fundamental Research Funds for the Central Universities,China(Grant No.WUT:2017IB013)
文摘To date, many efforts have been made to improve the performance of paintable carbon-based （PC-based） perovskite solar cells （PSCs）. Though great progress has been achieved, their power conversion efficiencies are still relatively low compared with hole-transport-materials-based PSCs. General research on influencing factors of performance in PC-based PSCs is still insufficient. In this work, PC-based PSCs were fabricated in ambient air and four groups of controlled experi- ments were performed in which the PbI2 layers were prepared with or without antisolvent extraction treatment. These four groups of experiments were designed to find out the effect of different influencing factors on PC-based PSCs performance, for example, PbI2 residual, the surface morphology of the perovskite film, the surface roughness of the perovskite film, and the contact status of the perovskite/carbon electrode interface. With a systematic analysis, we demonstrated that the contact status of the perovskite/carbon electrode interface played a vital role in PC-based PSCs, and a fiat, smooth perovskite surface could help to improve this contact status significantly. Besides, on the precondition of a poor contact interface, no PbI2 residual and a good surface morphology only brought limited benefits to the performances of PC-based PSCs.
基金Supported by the Research Fund of Heilongjiang Science & Technology Department(GB08D101-2)
文摘Taking a total of 13 areas in Heilongjiang commodity grain base as the research objects,9 indices are selected,which are regional GDP(X1),per capita GDP(X2),total value of tertiary industry(X3),financial revenue(X4),urban fixed assets investment(X5),average salary(X6),gross industrial output value(X7),total output value of farming,forestry,husbandry and fishing(X8),and retail sales of social consumer goods(X9).Based on this,evaluation index system of regional economy is established.According to the 2006-2008 Heilongjiang Statistical Yearbook,average values within 3 years are used as analytical data.Factor Analysis Method is adopted to establish regression model and to carry out comprehensive analysis.Result shows that Heilongjiang commodity grain base has extremely uneven regional economic development in different areas.According to the score order and actual situation,the 13 areas are divided into 4 types.The first and second types are Harbin and Daqing,respectively.The third type is Qiqihaer,Suihua,Mudanjiang and Jiamusi.And the forth type is Jixi,Shuangyashan,Heihe,Yichun,Qitaihe,Hegang and Daxinganling.Suggestions for the development of these areas are put forward.
基金supported by National High Technology Research and Development Program of China (863 Program) (No.2015AA016306)National Nature Science Foundation of China (No.61231015)National Nature Science Foundation of China (No.61671335)
文摘Object-based audio coding is the main technique of audio scene coding. It can effectively reconstruct each object trajectory, besides provide sufficient flexibility for personalized audio scene reconstruction. So more and more attentions have been paid to the object-based audio coding. However, existing object-based techniques have poor sound quality because of low parameter frequency domain resolution. In order to achieve high quality audio object coding, we propose a new coding framework with introducing the non-negative matrix factorization(NMF) method. We extract object parameters with high resolution to improve sound quality, and apply NMF method to parameter coding to reduce the high bitrate caused by high resolution. And the experimental results have shown that the proposed framework can improve the coding quality by 25%, so it can provide a better solution to encode audio scene in a more flexible and higher quality way.
文摘Focusing on controlling the press-assembly quality of high-precision servo mechanism,an intelligent early warning method based on outlier data detection and linear regression is proposed.Linear regression is used to deal with the relationship between assembly quality and press-assembly process,then the mathematical model of displacement-force in press-assembly process is established and a qualified press-assembly force range is defined for assembly quality control.To preprocess the raw dataset of displacement-force in the press-assembly process,an improved local outlier factor based on area density and P weight(LAOPW)is designed to eliminate the outliers which will result in inaccuracy of the mathematical model.A weighted distance based on information entropy is used to measure distance,and the reachable distance is replaced with P weight.Experiments show that the detection efficiency of the algorithm is improved by 5.6 ms compared with the traditional local outlier factor(LOF)algorithm,and the detection accuracy is improved by about 2%compared with the local outlier factor based on area density(LAOF)algorithm.The application of LAOPW algorithm and the linear regression model shows that it can effectively carry out intelligent early warning of press-assembly quality of high precision servo mechanism.
文摘目的:探究乳腺癌病人婚姻质量的影响因素。方法:检索Cochrane Library、PubMed、EMbase、Web of Science、中国生物医学文献数据库、中国知网、万方数据库和维普数据库中关于乳腺癌病人婚姻质量的队列研究、病例对照研究和横断面研究。采用Stata14.0软件对数据进行Meta分析。结果:共纳入15篇文献,总样本量为3 906例。乳腺癌病人婚姻质量的影响因素包括文化程度[OR=1.67,95%CI(1.00,2.80),P=0.05]、家庭经济收入[OR=12.21,95%CI(9.20,16.21),P<0.001]、婚姻状况[OR=2.10,95%CI(1.41,3.14),P<0.001]、医疗费用来源[OR=2.65,95%CI(2.34,3.00),P<0.001]、承担家务情况[OR=2.14,95%CI(1.67,4.29),P=0.032]、病程[OR=3.12,95%CI(2.08,4.70),P<0.001]、婚姻满意度[OR=3.55,95%CI(3.08,4.09),P<0.001]、性生活体验[OR=2.82,95%CI(2.40,3.33),P<0.001]、社会支持[OR=1.74,95%CI(1.35,2.23),P=0.032]。结论:乳腺癌严重影响女性病人的婚姻质量,护理人员应提高对乳腺癌病人婚姻质量的认识水平和重视程度,制订全程、精细和个性化的心理干预措施,以预防乳腺癌病人婚姻焦虑。
