Prospective real-world data from large patient samples,which re-port on the long-term effectiveness of the employed different drug therapies,are rare in Parkinson's disease(PD).The non interven-tional"Transde...Prospective real-world data from large patient samples,which re-port on the long-term effectiveness of the employed different drug therapies,are rare in Parkinson's disease(PD).The non interven-tional"Transdermal Rotigotine User Surveillance Study"(TRUST)trial represents such a real-world study.It investigated long-term treatment with different dopamine substituting treatment regimens in 2195 PD patients(Mfiller et al.,2018).Participation in TRUST meant that the treating neurologists were only asked to document and modify the dopaminergic drug regimen without any prior PD patient selection criteria.Thus this unique trial design reflects the real world of patient maintenance.展开更多
[提示]只要你是脑力劳动者,或是本科生,硕士生,博士生,此文对你的作用绝对不可小看。本文的标题,一语道破了文章之主旨:思维之创造性来自充足的睡眠: Problem-solving appear to be directly linked to adequate sleep. Sleep is often ...[提示]只要你是脑力劳动者,或是本科生,硕士生,博士生,此文对你的作用绝对不可小看。本文的标题,一语道破了文章之主旨:思维之创造性来自充足的睡眠: Problem-solving appear to be directly linked to adequate sleep. Sleep is often the best medicine. Creativity also appears to be enhanced in the process. Sleep can help to turn yesterday’s problem into today’s solution. 偌大校园,子夜时分,寝室里照样灯火通明,学子仍然谈笑风生,黎明时刻,寝室里照样鼾声四起,学子仍然独步梦境,这是何等令人揪心的场景!须知,你们的思维创造力就流失于此!展开更多
The equilibrium and kinetic characteristics of the adsorption of erythromycin to Sepabeads SP825 were determined.The equilibrium data in a batch system was well described by a Langmuir isotherm.The separation performa...The equilibrium and kinetic characteristics of the adsorption of erythromycin to Sepabeads SP825 were determined.The equilibrium data in a batch system was well described by a Langmuir isotherm.The separation performance was investigated in a fixed-bed system with respect to the adsorption superficial velocity,ionic strength and pH.A mathematical model was used to simulate the mass transfer mechanism,taking film mass transfer,pore diffusion and axial dispersion into account.The model predictions were consistent with the experi-mental data and were consequently used to determine the mass transfer coefficients.展开更多
文摘Prospective real-world data from large patient samples,which re-port on the long-term effectiveness of the employed different drug therapies,are rare in Parkinson's disease(PD).The non interven-tional"Transdermal Rotigotine User Surveillance Study"(TRUST)trial represents such a real-world study.It investigated long-term treatment with different dopamine substituting treatment regimens in 2195 PD patients(Mfiller et al.,2018).Participation in TRUST meant that the treating neurologists were only asked to document and modify the dopaminergic drug regimen without any prior PD patient selection criteria.Thus this unique trial design reflects the real world of patient maintenance.
文摘[提示]只要你是脑力劳动者,或是本科生,硕士生,博士生,此文对你的作用绝对不可小看。本文的标题,一语道破了文章之主旨:思维之创造性来自充足的睡眠: Problem-solving appear to be directly linked to adequate sleep. Sleep is often the best medicine. Creativity also appears to be enhanced in the process. Sleep can help to turn yesterday’s problem into today’s solution. 偌大校园,子夜时分,寝室里照样灯火通明,学子仍然谈笑风生,黎明时刻,寝室里照样鼾声四起,学子仍然独步梦境,这是何等令人揪心的场景!须知,你们的思维创造力就流失于此!
文摘The equilibrium and kinetic characteristics of the adsorption of erythromycin to Sepabeads SP825 were determined.The equilibrium data in a batch system was well described by a Langmuir isotherm.The separation performance was investigated in a fixed-bed system with respect to the adsorption superficial velocity,ionic strength and pH.A mathematical model was used to simulate the mass transfer mechanism,taking film mass transfer,pore diffusion and axial dispersion into account.The model predictions were consistent with the experi-mental data and were consequently used to determine the mass transfer coefficients.