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Construction of Constant Rank and Orbit Codes over Finite Chain Rings
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作者 GUO Ye LIU Xiusheng 《Wuhan University Journal of Natural Sciences》 2025年第3期289-301,共13页
In this paper,we first generalize the constant dimension and orbit codes over finite fields to the constant rank and orbit codes over finite chain rings.Then we provide a relationship between constant rank codes over ... In this paper,we first generalize the constant dimension and orbit codes over finite fields to the constant rank and orbit codes over finite chain rings.Then we provide a relationship between constant rank codes over finite chain rings and constant dimension codes over the residue fields.In particular,we prove that an orbit submodule code over a finite chain ring is a constant rank code.Finally,for special finite chain ring F_(q)+γF_(q),we define a Gray mapφfrom(F_(q)+γF_(q))^(n)to F^(2n)_(q),and by using cyclic codes over F_(q)+γF_(q),we obtain a method of constructing an optimum distance constant dimension code over F_(q). 展开更多
关键词 finite chain ring rank of linear codes constant rank codes orbit codes
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Surface reconstruction of complex contour lines based on chain code matching technique 被引量:1
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作者 姜晓彤 《Journal of Southeast University(English Edition)》 EI CAS 2005年第4期432-435,共4页
A new method for solving the tiling problem of surface reconstruction is proposed. The proposed method uses a snake algorithm to segment the original images, the contours are then transformed into strings by Freeman'... A new method for solving the tiling problem of surface reconstruction is proposed. The proposed method uses a snake algorithm to segment the original images, the contours are then transformed into strings by Freeman' s code. Symbolic string matching technique is applied to establish a correspondence between the two consecutive contours. The surface is composed of the pieces reconstructed from the correspondence points. Experimental results show that the proposed method exhibits a good behavior for the quality of surface reconstruction and its time complexity is proportional to mn where m and n are the numbers of vertices of the two consecutive slices, respectively. 展开更多
关键词 chain code string matching surface reconstruction local shape feature
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Multiple fault diagnosis of down-hole conditions of sucker-rod pumping wells based on Freeman chain code and DCA 被引量:13
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作者 LI Kun GAO Xian-wen +2 位作者 YANG Wei-bing DAI Ying-long TIAN Zhong-da 《Petroleum Science》 SCIE CAS CSCD 2013年第3期347-360,共14页
It is important to achieve continuous, stable and efficient pumping well operation in actual oilfield operation. Down-hole pumping well working conditions can be monitored in real-time and a reasonable production sche... It is important to achieve continuous, stable and efficient pumping well operation in actual oilfield operation. Down-hole pumping well working conditions can be monitored in real-time and a reasonable production scheme can be designed when computer diagnosis is used. However, it is difficult to make a comprehensive analysis to supply efficient technical guidance for operation of the pumping well with multiple faults of down-hole conditions, which cannot be effectively dealt with by the common methods. To solve this problem, a method based on designated component analysis (DCA) is used in this paper. Freeman chain code is used to represent the down-hole dynamometer card whose important characteristics are extracted to construct a designated mode set. A control chart is used as a basis for fault detection. The upper and lower control lines on the control chart are determined from standard samples in normal working conditions. In an incompletely orthogonal mode, the designated mode set could be divided into some subsets in which the modes are completely orthogonal. The observed data is projected into each designated mode to realize fault detection according to the upper and lower control lines. The examples show that the proposed method can effectively diagnose multiple faults of down-hole conditions. 展开更多
关键词 Sucker-rod pumping wells multiple faults designated component analysis control chart Freeman chain code dynamometer card
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Self-Dual Permutation Codes over Finite Chain Rings 被引量:1
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作者 YUAN Yuan ZHANG Huanguo 《Wuhan University Journal of Natural Sciences》 CAS 2007年第6期992-996,共5页
Permutation codes over finite chain rings are introduced; by using the character of the finite chain rings and the knowledge of representation of group, some conditions for existence or non-existence of self-dual perm... Permutation codes over finite chain rings are introduced; by using the character of the finite chain rings and the knowledge of representation of group, some conditions for existence or non-existence of self-dual permutation codes over finite chain rings are obtained. Specially, when the group is a direct product of a 2-group and a T-group, and the group action is transitive, the sufficient and necessary condition of the existence of permutation codes is given. 展开更多
关键词 finite chain ring group code permutation code self-dual code
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Face Recognition Using Chain Codes
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作者 Nazmeen B. Boodoo-Jahangeer Sunilduth Baichoo 《Journal of Signal and Information Processing》 2013年第3期154-157,共4页
Face recognition is an active area of biometrics. This study investigates the use of Chain Codes as features for recognition purpose. Firstly a segmentation method, based on skin color model was applied, followed by c... Face recognition is an active area of biometrics. This study investigates the use of Chain Codes as features for recognition purpose. Firstly a segmentation method, based on skin color model was applied, followed by contour detection, then the chain codes of the contours were determined. The first difference of chain codes were calculated since the latter is invariant to rotation. The features were calculated and stored in a matrix. Experiments were performed using the University of Essex Face database, and results show a recognition rate of 95% with this method, when compared with Principal Components Analysis (PCA) giving 87.5% recognition rate. 展开更多
关键词 FACE RECOGNITION BIOMETRICS chain codeS PCA
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多发性子宫肌瘤剔除术前后彩色多普勒超声参数、lncRNA XIST变化对术后复发评估价值
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作者 陈果 王荔 +1 位作者 胡科丹 张柯 《中国妇幼健康研究》 2026年第3期100-106,共7页
目的分析多发性子宫肌瘤剔除术前后彩色多普勒超声(CDFI)参数、长链非编码RNA X染色体失活特异转录本(lncRNA XIST)变化对术后复发的评估价值。方法选取2022年1月至2024年2月泸州市人民医院收治的196例拟行多发性子宫肌瘤剔除术患者作... 目的分析多发性子宫肌瘤剔除术前后彩色多普勒超声(CDFI)参数、长链非编码RNA X染色体失活特异转录本(lncRNA XIST)变化对术后复发的评估价值。方法选取2022年1月至2024年2月泸州市人民医院收治的196例拟行多发性子宫肌瘤剔除术患者作为研究对象,根据术后6个月是否复发分为复发组和未复发组,采用倾向性评分匹配(PSM)来降低组间选择偏倚。采用Voluson E10型彩色多普勒超声诊断仪测定术前、术后1个月舒张期血流速度(EDV)、收缩期血流速度(PSV)、子宫阻力指数(UtA-RI)、子宫搏动指数(UtA-PI),采用实时荧光定量聚合酶链式反应(qRT-PCR)测定术前、术后1个月lncRNA XIST,采用Logistic回归方程分析CDFI参数、lncRNA XIST与多发性子宫肌瘤剔除术后复发的关系,采用受试者工作特征(ROC)曲线分析模型预测价值。结果术后6个月,研究对象中共有5例失访,55例(28.79%)复发;匹配后复发组术前lncRNA XIST、EDV、PSV、UtA-PI高于未复发组,UtA-RI低于未复发组,差异有统计学意义(t值介于11.733~16.918之间,P<0.05);ROC曲线显示,术前lncRNA XIST、EDV、PSV、UtA-PI、UtA-RI预测多发性子宫肌瘤剔除术后复发的曲线下面积(AUC)分别为0.754、0.766、0.792、0.776、0.742,联合预测的AUC为0.918,灵敏度为81.82%,特异度为92.73%,联合预测AUC高于单独预测(Z值介于2.215~3.340之间,P<0.001);按截断值分组,lncRNA XIST、EDV、PSV、UtA-RI、UtA-PI高值患者复发风险是低值患者的1.647、1.875、1.406、0.700、1.664倍。结论lncRNA XIST、EDV、PSV、UtA-PI、UtA-RI异常均会增加多发性子宫肌瘤剔除术后复发风险,五者联合有助于提高预测价值,指导临床诊治。 展开更多
关键词 子宫肌瘤 多发性 腹腔镜子宫肌瘤剔除术 复发 彩色多普勒超声 长链非编码RNA X染色体失活特异转录本
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哮喘患者血清lncRNA HOTTIP和RMRP水平表达及与气道重塑的相关性分析
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作者 郁芳芳 谢伟国 许群 《现代检验医学杂志》 2026年第1期70-74,85,共6页
目的探究哮喘患者血清长链非编码RNA(lncRNA)HOXA末端转录本反义RNA(HOTTIP)和线粒体RNA处理核糖核酸内切酶RNA组份(RMRP)表达变化及其与气道重塑的相关性。方法选取2022年1月~2024年6月江苏省江阴市人民医院呼吸与危重症医学科收治的... 目的探究哮喘患者血清长链非编码RNA(lncRNA)HOXA末端转录本反义RNA(HOTTIP)和线粒体RNA处理核糖核酸内切酶RNA组份(RMRP)表达变化及其与气道重塑的相关性。方法选取2022年1月~2024年6月江苏省江阴市人民医院呼吸与危重症医学科收治的急性发作期哮喘患者72例为急性发作期组,同期门诊随访哮喘缓解期患者70例为缓解期组,健康体检者142例为健康对照组。采用实时荧光定量聚合酶链反应(qRT-PCR)检测血清lncRNA HOTTIP和RMRP水平。采用多排螺旋CT测量患者肺内气道的内径(L)、外径(D),计算气道壁厚度与气道外径比值(T/D)和管壁面积占支气道总横截面积百分比(WA%)。采用肺功能检测仪检测第一秒用力呼气量(FEV1)、最高呼吸气流(PEF)水平。Spearman相关性分析哮喘患者血清lncRNA HOTTIP和RMRP水平与哮喘控制测试(ACT)评分的关系。Pearson相关性分析哮喘患者血清lncRNA HOTTIP和RMRP水平以及与肿瘤坏死因子-α(TNF-α)、γ干扰素(IFN-γ)、白细胞介素-18(IL-18)水平、气道重塑以及肺功能指标的关系。结果与健康对照组相比,急性发作期组和缓解期组IFN-γ水平显著降低(t=14.161,8.886),TNF-α、IL-18、lncRNA HOTTIP(1.32±0.15、1.15±0.15 vs 1.01±0.14)和RMRP(1.27±0.14、1.16±0.14 vs 1.02±0.13)水平显著升高(t=9.345~28.361);与缓解期组相比,急性发作期组ACT评分、IFN-γ水平显著降低(t=13.344,4.475),TNF-α、IL-18、lncRNA HOTTIP和RMRP水平显著升高(t=6.861~15.675),差异具有统计学意义(均P<0.05)。与健康对照组相比,急性发作期组和缓解期组FEV1、PEF水平显著降低(t=13.346~55.694),T/D、WA%水平显著升高(t=19.145~33.035);与缓解期组相比,急性发作期组FEV1、PEF水平显著降低(t=21.802、21.446),T/D、WA%水平显著升高(t=9.994、10.082),差异具有统计学意义(均P<0.05)。Spearman相关性分析显示哮喘患者血清lncRNA HOTTIP和RMRP水平与ACT评分呈负相关(r=-0.614、-0.399,均P<0.001)。Pearson相关性分析显示,哮喘患者血清lncRNA HOTTIP和RMRP水平呈正相关(r=0.625,P<0.05)。哮喘患者血清lncRNA HOTTIP和RMRP水平与TNF-α(r=0.658、0.632)、IL-18(r=0.584、0.586)、T/D(r=0.604、0.631)、WA%(r=0.597、0.588)水平呈正相关,与IFN-γ(r=-0.587、-0.517)、FEV1(r=-0.568、-0.577)、PEF(r=-0.634、-0.627)水平呈负相关(均P<0.05)。结论哮喘患者血清lncRNA HOTTIP和RMRP水平均呈高表达,与气道重塑和肺功能指标变化有关。 展开更多
关键词 哮喘 长链非编码核糖核酸HOXA末端转录本反义RNA 线粒体RNA处理核糖核酸内切酶RNA组份 气道重塑
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LncRNA-14238/TLR-7信号通路参与腰椎间盘突出症痛觉高敏的机制研究
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作者 张磊 白明生 喻新祥 《颈腰痛杂志》 2026年第1期13-18,共6页
目的 探讨长链非编码核糖核酸-14238(LncRNA-14238)/Toll样受体-7(TLR-7)信号通路参与腰椎间盘突出症(LDH)痛觉高敏的机制。方法 68只雄性Sprague-Dawley大鼠分为正常组、LDH组和小干扰长链非编码核糖核酸(si LncRNA)组,采用自体髓核植... 目的 探讨长链非编码核糖核酸-14238(LncRNA-14238)/Toll样受体-7(TLR-7)信号通路参与腰椎间盘突出症(LDH)痛觉高敏的机制。方法 68只雄性Sprague-Dawley大鼠分为正常组、LDH组和小干扰长链非编码核糖核酸(si LncRNA)组,采用自体髓核植入左侧L5/L6神经根旁构建LDH模型,正常组仅行手术操作但不植入髓核,高通量测序检测LncRNA-14238的表达,此外,通过疼痛行为测试、承重实验和旋转杆分析检测LDH模型的痛觉高敏反应,实时荧光定量聚合酶链反应(qRT-PCR)和蛋白质印迹检测LncRNA-14238、TLR-7和内源性酶胱硫氨酸-β合成酶(CBS)的表达。结果 与正常组相比,LncRNA-14238、TLR-7和CBS在LDH组中表达升高,si LncRNA组的LncRNA-14238、TLR-7和CBS表达降低;LDH组的痛觉高敏反应增加,而沉默LncRNA-14238降低了LDH组的痛觉高敏反应,差异有统计学意义(P<0.05)。结论 LncRNA-14238/TLR-7信号通路可能参与LDH痛觉高敏反应。 展开更多
关键词 长链非编码核糖核酸-14238 Toll样受体-7 腰椎间盘突出症 痛觉高敏反应 内源性酶胱硫氨酸-β合成酶 高通量测序
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Auto-selection order of Markov chain for background sequences with chi-square test
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作者 谢雪英 孙啸 陆祖宏 《Journal of Southeast University(English Edition)》 EI CAS 2003年第4期311-316,共6页
Modeling non coding background sequences appropriately is important for the detection of regulatory elements from DNA sequences. Based on the chi square statistic test, some explanations about why to choose higher ... Modeling non coding background sequences appropriately is important for the detection of regulatory elements from DNA sequences. Based on the chi square statistic test, some explanations about why to choose higher order Markov chain model and how to automatically select the proper order are given in this paper. The chi square test is first run on synthetic data sets to show that it can efficiently find the proper order of Markov chain. Using chi square test, distinct higher order context dependences inherent in ten sets of sequences of yeast S.cerevisiae from other literature have been found. So the Markov chain with higher order would be more suitable for modeling the non coding background sequences than an independent model. 展开更多
关键词 non coding sequences regulatory elements chi square test Markov chain
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LncRNA PVT1靶向miR-18b-5p参与牙髓间充质干细胞成牙本质分化的作用机制
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作者 郑郁 翟桐 +1 位作者 崔敏 刘飞 《上海口腔医学》 2026年第1期35-41,共7页
目的:分析长链非编码核糖核酸(LncRNA)浆细胞瘤多样异位基因1(PVT1)靶向微小核糖核酸-18b-5p(miR-18b-5p)参与牙髓间充质干细胞(dental pulp mesenchymal stem cells,DPMSCs)成牙本质分化的作用机制。方法:分离培养人DPMSCs,油红O、茜... 目的:分析长链非编码核糖核酸(LncRNA)浆细胞瘤多样异位基因1(PVT1)靶向微小核糖核酸-18b-5p(miR-18b-5p)参与牙髓间充质干细胞(dental pulp mesenchymal stem cells,DPMSCs)成牙本质分化的作用机制。方法:分离培养人DPMSCs,油红O、茜素红、阿利新蓝染色鉴定,流式细胞术检测细胞表面标记分子。以2×10^(4)个细胞/cm^(2)的密度将细胞接种于24孔板,分为PVT1上调+miR-18b-5p下调组(转染pcDNA-PVT1和antagomiR-18b-5p)、PVT1下调+miR-18b-5p上调组(转染si-PVT1和agomiR-18b-5p)、空载1组(转染NC pcDNA)、空载2组(转染ago-NC)、PVT1上调+空载2组(转染pcDNA-PVT1和空载体2)、空载1+miR-18b-5p下调组(转染空载体1和antagomiR-18b-5p)和空白组。7天后茜素红染色观察细胞钙矿化情况,试剂盒检测碱性磷酸酯酶(ALP)活性。实时荧光定量PCR(RT-qPCR)检测各组LncRNA PVT1、miR-18b-5p与牙本质涎磷蛋白(DSPP)、骨钙素(OCN)、Runt相关转录因子2(RUNX2)基因表达。免疫印迹法(Western blot)检测各组DSPP、OCN和RUNX2蛋白表达。双荧光素酶报告基因检测实验探讨LncRNA PVT1与miR-18b-5p的靶向关系。结果:成功分离人DPMSCs并经油红O、茜素红、阿利新蓝染色和流式细胞术鉴定。PVT1上调+miR-18b-5p下调组成牙本质分化活性最强(P<0.05),PVT1下调+miR-18b-5p上调组则最弱(P<0.05)。PVT1上调+miR-18b-5p下调组LncRNA PVT1、DSPP、OCN和RUNX2表达最高(P<0.05),miR-18b-5p表达最低(P<0.05),PVT1下调+miR-18b-5p上调组相反(P<0.05)。LncRNA PVT1与miR-18b-5p存在结合位点,且LncRNA PVT1可负反馈靶向miR-18b-5p。结论:上调LncRNA PVT1可靶向抑制miR-18b-5p,促进人DPMSCs成牙本质分化,推测与上调DSPP、OCN和RUNX2表达有关。 展开更多
关键词 长链非编码核糖核酸 浆细胞瘤多样异位基因1 微小核糖核酸-18b-5p 牙髓间充质干细胞 成牙本质分化
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LncRNA MIAT调控食管鳞癌细胞增殖、迁移和侵袭的研究
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作者 范志勤 刘英敏 +1 位作者 米尔阿力木江·麦麦提吐尔逊 马遇庆 《新疆医科大学学报》 2026年第1期42-50,共9页
目的 明确长链非编码RNA心肌梗死相关转录本(Long chain non-coding RNA myocardial infarction associated transcript, lncRNA MIAT)在食管鳞癌(Esophageal squamous cell carcinoma, ESCC)中的表达和临床意义以及对ESCC细胞生物学行... 目的 明确长链非编码RNA心肌梗死相关转录本(Long chain non-coding RNA myocardial infarction associated transcript, lncRNA MIAT)在食管鳞癌(Esophageal squamous cell carcinoma, ESCC)中的表达和临床意义以及对ESCC细胞生物学行为的影响。方法 通过癌症基因组图谱(The cancer genome atlas, TCGA)数据库分析lncRNA MIAT在食管癌中的表达,60例ESCC患者的组织标本采用实时荧光定量聚合酶链反应(Quantitative real-time polymerase chain reaction, qRT-PCR)检测lncRNA MIAT的表达水平,并分析其与患者病理特征的关系。进一步将MIAT干扰慢病毒(LV-MIAT-RNAi)和阴性对照病毒(sh-NC)转染至TE-1和ECA109细胞,分为实验组(shMIAT组)和空载组(vector组),未做任何处理的TE-1和ECA109细胞作为空白对照组(control组)。通过细胞功能学实验分析lncRNA MIAT对ESCC细胞增殖、细胞凋亡、细胞周期、细胞迁移和侵袭的影响;利用Western blot检测沉默lncRNA MIAT对TE-1和ECA109细胞上皮间充质转化(Epithelial-mesenchymal transition, EMT)中蛋白表达情况。最后通过裸鼠皮下成瘤实验分析不同分组中荷瘤裸鼠瘤体的重量及体积变化情况。结果 TCGA数据库中数据显示,lncRNA MIAT在食管癌组织中的表达升高,在ESCC癌组织中lncRNA MIAT的表达量(0.26±0.63)较癌旁组织(0.08±0.27)升高(t=3.097,P=0.008)。lncRNA MIAT的表达水平与肿瘤大小、分化程度和淋巴结转移相关(P均<0.05)。在TE-1与ECA109细胞中,shMIAT组相较于control组和vector组,表现出细胞增殖率降低、凋亡率升高、迁移与侵袭细胞数目减少;同时,E-cadherin蛋白表达水平上升而N-cadherin表达水平下降(P均<0.05)。沉默lncRNA MIAT可提高G0/G1期的比例,降低G2/M期的比例。荷瘤裸鼠体内实验表明,与control组及vector组相比,shMIAT组裸鼠的皮下肿瘤体积更小、重量更轻(P<0.05)。结论 lncRNA MIAT在ESCC组织中高表达,沉默lncRNA MIAT可抑制ESCC细胞的增殖、迁移和侵袭能力,减轻裸鼠瘤体的重量,减小体积,lncRNA MIAT在ESCC中发挥促癌作用。 展开更多
关键词 食管鳞癌 lncRNA MIAT 细胞增殖 细胞迁移
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lncRNA663调控CLDN10表达及猪流行性腹泻病毒复制的功能分析
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作者 吴作林 梁海江 +3 位作者 吴哲豫 杨松柏 赵阿勇 钦伟云 《畜牧兽医学报》 北大核心 2026年第2期945-954,共10页
猪流行性腹泻病毒(porcine epidemic diarrhea virus,PEDV)是一种引起仔猪急性腹泻、呕吐及脱水等临床症状的冠状病毒,对全球猪养殖业造成了严重的经济损失。越来越多的研究报道长链非编码RNA(lncRNA)在猪冠状病毒中发挥着重要的调控作... 猪流行性腹泻病毒(porcine epidemic diarrhea virus,PEDV)是一种引起仔猪急性腹泻、呕吐及脱水等临床症状的冠状病毒,对全球猪养殖业造成了严重的经济损失。越来越多的研究报道长链非编码RNA(lncRNA)在猪冠状病毒中发挥着重要的调控作用,然而,关于lncRNA663在PEDV感染中的调控作用和机制研究尚未有相关报道。基于前期高通量转录组数据分析,笔者发现lncRNA 663与紧密连接蛋白CLDN10具有共表达趋势,因此本研究以lncRNA 663和CLDN10为试验对象,探索其在PEDV感染中的调控作用。本研究qRT-PCR和Western blot结果显示,PEDV感染IPEC-J2细胞后上调了lncRNA 663和CLDN10的表达水平(P<0.05),DSS处理则显著降低了lncRNA 663和CLDN10的表达水平(P<0.05)。亚细胞定位预测发现lncRNA 663主要定位于细胞质,RPISeq预测发现lncRNA663和CLDN10高度互作(SVM:0.98,RF:0.8);功能试验结果显示,siRNAs敲低lncRNA 663后,CLDN10的mRNA和蛋白表达水平显著下降,PEDV复制水平亦同步降低(P<0.05)。进一步通过AlphaFold3和ChimeraX进行结构预测,发现CLDN10可能与PEDV S蛋白形成7个氢键结合位点,提示其可能参与病毒侵染过程。综上所述,本研究初步揭示lncRNA 663通过调控CLDN10表达促进PEDV复制的可能机制,为深入解析病毒与宿主非编码RNA互作关系及干预靶点提供参考。 展开更多
关键词 猪流行性腹泻病毒 长链非编码RNA CLDN10 肠道屏障
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lncRNA XIST靶向miR-182-5p/HIF-2α分子轴对滋养层细胞生物学行为特性影响的机制研究
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作者 黄燕 张林静 +2 位作者 汪洪林 张婷 李波 《中国比较医学杂志》 北大核心 2026年第6期11-20,共10页
目的探究长链非编码RNA(lncRNA)X染色体失活特异性转录本(XIST)调控滋养层细胞生物学活性的分子机制。方法体外培养人绒毛膜滋养层细胞HTR-8/Svneo,分为对照组、干扰空载组(转染siNC)和si-XIST-1组(转染si-XIST-1)、si-XIST-1+anti-NC组... 目的探究长链非编码RNA(lncRNA)X染色体失活特异性转录本(XIST)调控滋养层细胞生物学活性的分子机制。方法体外培养人绒毛膜滋养层细胞HTR-8/Svneo,分为对照组、干扰空载组(转染siNC)和si-XIST-1组(转染si-XIST-1)、si-XIST-1+anti-NC组(共转染si-XIST-1和anti-NC)、si-XIST-1+anti-182-5p组(共转染si-XIST-1和anti-182-5p)。采用RT-qPCR检测细胞中XIST、miR-182-5p和低氧诱导因子2α(HIF-2α)mRNA表达;CCK-8实验和EdU实验检测细胞增殖活力;流式细胞术检测细胞凋亡;划痕愈合实验、Transwell实验检测细胞迁移、侵袭能力;Western blot检测细胞中HIF-2α、cleaved-caspase-3、Bcl-2、Bax、基质金属蛋白(MMP)-2、MMP-9蛋白表达;双荧光素酶报告实验验证miR-182-5p与XIST、HIF-2α的靶向关系。结果与对照组、干扰空载组比较,si-XIST-1组XIST、HIF-2αmRNA水平、凋亡率及HIF-2α、cleaved-caspase-3、Bax蛋白水平降低,miR-182-5p水平、细胞活力、EdU阳性率、划痕愈合率、侵袭细胞数及Bcl-2、MMP-2、MMP-9蛋白水平升高(P<0.05);与si-XIST-1组和si-XIST-1+anti-NC组比较,si-XIST-1+anti-182-5p组HIF-2αmRNA水平、凋亡率及HIF-2α、cleaved-caspase-3、Bax蛋白水平升高,miR-182-5p水平、细胞活力、EdU阳性率、划痕愈合率、侵袭细胞数及Bcl-2、MMP-2、MMP-9蛋白水平降低(P<0.05)。lncRNA XIST可靶向HTR-8/Svneo细胞中的miR-182-5p,HIF-2α是miR-182-5p的靶标。结论敲低lncRNA XIST可能是通过竞争性结合miR-182-5p来抑制HIF-2α表达,进而增强HTR-8/Svneo细胞增殖、迁移和侵袭能力,并抑制细胞凋亡。 展开更多
关键词 子痫前期 长链非编码RNA X染色体失活特异性转录本 microRNA-182 低氧诱导因子2α 滋养层细胞
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基于链码标定的皮带秤计量优化及稳定性提升研究
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作者 杨小燕 《计量与测试技术》 2026年第3期104-108,共5页
本文基于皮带秤在化工计量领域应用现状,通过探讨实物检定与链码标定的原理、步骤及优缺点,研究如何将实物检定与链码标定互补结合,从而开展有效的企业内部期间核查,进而提升其测量的稳定性。
关键词 皮带秤 实物检定 链码标定 企业内部期间核查
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血清长链非编码RNA SIX3OS1在阿尔茨海默病中的表达水平及其与蛋白生物标志物的关联分析
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作者 王巧改 郝玉青 +2 位作者 刘秀红 刘军 李芳 《国际神经病学神经外科学杂志》 2026年第1期28-32,共5页
目的探讨长链非编码RNA SIX3OS1(LncRNA SIX3OS1)在阿尔茨海默病(AD)患者中的表达水平及其与蛋白生物标志物中的β-淀粉样蛋白1-42(Aβ1-42)、磷酸化tau蛋白217(P-tau 217)、神经丝轻链蛋白(NFL)的关联性。方法纳入157例AD患者(AD组)和4... 目的探讨长链非编码RNA SIX3OS1(LncRNA SIX3OS1)在阿尔茨海默病(AD)患者中的表达水平及其与蛋白生物标志物中的β-淀粉样蛋白1-42(Aβ1-42)、磷酸化tau蛋白217(P-tau 217)、神经丝轻链蛋白(NFL)的关联性。方法纳入157例AD患者(AD组)和45名体检正常者(对照组)。依据临床痴呆评定量表(CDR)评分将AD患者分为轻度AD组(65例)和中重度AD组(92例)。应用受试者操作特征(ROC)曲线分析LncRNA SIX3OS1联合Aβ1-42、P-tau 217及NFL对AD的预测价值。采用皮尔逊相关系数分析AD患者血清LncRNA SIX3OS1表达水平与Aβ1-42、P-tau 217及NFL的相关性。结果AD组血清LncRNA SIX3OS1、Aβ1-42、P-tau 217及NFL水平均高于对照组(P<0.001)。中重度AD组血清LncRNA SIX3OS1、Aβ1-42、P-tau 217及NFL水平高于轻度AD组(P<0.001)。ROC曲线分析显示,LncRNA SIX3OS1联合Aβ1-42、P-tau 217及NFL预测AD的曲线下面积为0.977,准确度为95.38%。相关分析显示,AD患者血清LncRNA SIX3OS1表达水平与Aβ1-42、P-tau 217及NFL均呈正相关(P<0.001)。结论AD患者血清LncRNA SIX3OS1表达水平升高,其高表达与蛋白生物标志物异常相关,LncRNA SIX3OS1联合Aβ1-42、P-tau 217及NFL对AD具有较好的筛查价值。 展开更多
关键词 阿尔茨海默病 长链非编码RNA SIX3OS1 β-淀粉样蛋白1-42 磷酸化tau蛋白217 神经丝轻链蛋白
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CYCLIC AND NEGACYCLIC CODES OF LENGTH 2p^s OVER F_(p^m) + uF_(p^m) 被引量:2
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作者 刘修生 许小芳 《Acta Mathematica Scientia》 SCIE CSCD 2014年第3期829-839,共11页
In this article, we focus on cyclic and negacyclic codes of length 2p^s over the ring R = Fp^m + uFp^m, where p is an odd prime. On the basis of the works of Dinh (in J.Algebra 324,940-950,2010), we use the Chinese... In this article, we focus on cyclic and negacyclic codes of length 2p^s over the ring R = Fp^m + uFp^m, where p is an odd prime. On the basis of the works of Dinh (in J.Algebra 324,940-950,2010), we use the Chinese Remainder Theorem to establish the algebraic structure of cyclic and negacyclic codes of length 2p^s over the ring Fp^m + uFp^m in terms of polynomial generators. Furthermore, we obtain the number of codewords in each of those cyclic and negacyclic codes. 展开更多
关键词 Negacyclic codes cyclic codes repeated-root codes finite chain ring finite local ring
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血清IgκC、LncRNA SNHG7水平与急性髓系白血病病情严重程度及预后的关联
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作者 芦涛 潘海粟 邓刚 《现代临床医学》 2026年第1期22-25,共4页
目的:分析血清免疫球蛋白κ链C区蛋白(IgκC)、长链非编码RNA小核仁RNA宿主基因7(LncRNA SNHG7)水平与急性髓系白血病(AML)病情进展及预后的关联。方法:回顾性分析我院2022年1月至2023年11月收治的115例AML患者的临床资料,依据病情严重... 目的:分析血清免疫球蛋白κ链C区蛋白(IgκC)、长链非编码RNA小核仁RNA宿主基因7(LncRNA SNHG7)水平与急性髓系白血病(AML)病情进展及预后的关联。方法:回顾性分析我院2022年1月至2023年11月收治的115例AML患者的临床资料,依据病情严重程度将其分为重症组(n=35)和轻症组(n=80),比较两组患者的血清IgκC、LncRNA SNHG7水平及血常规指标,分析血清IgκC、LncRNA SNHG7水平与血常规指标的相关性及两者联合检测对AML患者发生不良预后的预测价值。结果:重症组的IgκC、LncRNA SNHG7水平均高于轻症组(P<0.05);重症组的白细胞计数(WBC)高于轻症组,红细胞计数(RBC)、血小板计数(PLT)、中性粒细胞计数(Neu)均低于轻症组(P<0.05);IgκC、LncRNA SNHG7水平分别与WBC呈正相关,与RBC、PLT、Neu呈负相关(P<0.05);115例AML患者的不良预后发生率为17.39%(20/115),预后不良组(n=20)的IgκC、LncRNA SNHG7水平均高于预后良好组(n=95,P<0.05);IgκC、LncRNA SNHG7联合检测对AML患者发生不良预后的预测灵敏度、特异度分别为93.11%、81.25%,均高于两者单独检测(AUC=0.935>0.866、0.864,P<0.05)。结论:IgκC、LncRNA SNHG7水平与AML患者的病情严重程度呈正相关,两者联合检测可实现对患者发生不良预后的早期预测。 展开更多
关键词 急性髓系白血病 免疫球蛋白κ链C区蛋白 长链非编码RNA小核仁RNA宿主基因7 病情严重程度 不良预后
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CYCLIC CODES OVER FORMAL POWER SERIES RINGS 被引量:1
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作者 Dougherty Steven T. 刘宏伟 《Acta Mathematica Scientia》 SCIE CSCD 2011年第1期331-343,共13页
In this article, cyclic codes and negacyclic codes over formal power series rings are studied. The structure of cyclic codes over this class of rings is given, and the relationship between these codes and cyclic codes... In this article, cyclic codes and negacyclic codes over formal power series rings are studied. The structure of cyclic codes over this class of rings is given, and the relationship between these codes and cyclic codes over finite chain rings is obtained. Using an isomorphism between cyclic and negacyclic codes over formal power series rings, the structure of negacyclic codes over the formal power series rings is obtained. 展开更多
关键词 Finite chain rings cyclic codes negacyclic codes γ-adic codes
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Adding Sub-chain Method for Structural Synthesis of Planar Closed Kinematic Chains 被引量:2
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作者 DENG Zongquan YANG Fei TAO Jianguo 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2012年第2期206-213,共8页
For at least the past five decades,structural synthesis has been used as a main means of finding better mechanisms with some predefined function.In structural synthesis,isomorphism identification is still a problem un... For at least the past five decades,structural synthesis has been used as a main means of finding better mechanisms with some predefined function.In structural synthesis,isomorphism identification is still a problem unsolved well,and to solve this problem is very significant to the design of new mechanisms.According to the given degree of freedom(DOF) and link connection property of planar closed chain mechanisms,vertex assortment is obtained.For solving the isomorphism problem,a method of the adding sub-chains is proposed with the detailed steps and algorithms in the synthesizing process.Employing this method,the identification code and formation code of every topological structure are achieved,therefore many isomorphic structures could be eliminated in time during structural synthesis by comparing those codes among different topological graphs,resulting in the improvement of synthesizing efficiency and accuracy,and the approach for eliminating rigid sub-chains in and after the synthesizing process is also presented.Some examples are given,including how to add sub-chains,how to detect simple rigid sub-chains and how to obtain identification codes and formulation codes et al.Using the adding sub-chain method,the relative information of some common topological graphs is given in the form of table.The comparison result is coincident with many literatures,so the correctness of the adding sub-chain method is convinced.This method will greatly improve the synthesizing efficiency and accuracy,and has a good potential for application. 展开更多
关键词 structural synthesis adding sub-chain method identification code formation code rigid sub-chains
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ON THE CHARACTERIZATION OF CYCLIC CODES OVER TWO CLASSES OF RINGS
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作者 刘修生 《Acta Mathematica Scientia》 SCIE CSCD 2013年第2期413-422,共10页
Let R be a finite chain ring with maximal ideal (7) and residue field F,and letγ be of nilpotency index t. To every code C of length n over R, a tower of codes C = (C : γ0) C_ (C: 7) C ... C_ (C: γ2) C_ ... Let R be a finite chain ring with maximal ideal (7) and residue field F,and letγ be of nilpotency index t. To every code C of length n over R, a tower of codes C = (C : γ0) C_ (C: 7) C ... C_ (C: γ2) C_ .-. C_ (C:γ^t-1) can be associated with C, where for any r C R, (C : r) = {e C Rn I re E C}. Using generator elements of the projection of such a tower of codes to the residue field F, we characterize cyclic codes over R. This characterization turns the condition for codes over R to be cyclic into one for codes over the residue field F. Furthermore, we obtain a characterization of cyclic codes over the formal power series ring of a finite chain ring. 展开更多
关键词 Finite chain rings formal power series rings cyclic codes tower of codes Hensel lift
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