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Disparity in immigrant compulsory care assignment: discrimination or response to treatment need
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作者 Steven P Segal Leena Badran +1 位作者 Lachlan Rimes Vinay Lakra 《General Psychiatry》 2025年第3期234-241,共8页
INTRODUCTION Reports indicating that culturally and linguistically diverse(CALD)people-often with migrant backgrounds-in Australia and New Zealand are more likely to be placed in compulsory community treatment(CCT)hav... INTRODUCTION Reports indicating that culturally and linguistically diverse(CALD)people-often with migrant backgrounds-in Australia and New Zealand are more likely to be placed in compulsory community treatment(CCT)have rightlyraised concernsthat such action might be discriminatory. 展开更多
关键词 NEED compulsory community treatment cct DISPARITY response IMMIGRANT assignment DISCRIMINATION compulsory care
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Towards intelligent and trustworthy task assignments for 5G-enabled industrial communication systems
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作者 Mingfeng Huang Anfeng Liu +1 位作者 Neal N.Xiong Athanasios V.Vasilakos 《Digital Communications and Networks》 2025年第1期246-255,共10页
With the unprecedented prevalence of Industrial Internet of Things(IIoT)and 5G technology,various applications supported by industrial communication systems have generated exponentially increased processing tasks,whic... With the unprecedented prevalence of Industrial Internet of Things(IIoT)and 5G technology,various applications supported by industrial communication systems have generated exponentially increased processing tasks,which makes task assignment inefficient due to insufficient workers.In this paper,an Intelligent and Trustworthy task assignment method based on Trust and Social relations(ITTS)is proposed for scenarios with many tasks and few workers.Specifically,ITTS first makes initial assignments based on trust and social influences,thereby transforming the complex large-scale industrial task assignment of the platform into the small-scale task assignment for each worker.Then,an intelligent Q-decision mechanism based on workers'social relation is proposed,which adopts the first-exploration-then-utilization principle to allocate tasks.Only when a worker cannot cope with the assigned tasks,it initiates dynamic worker recruitment,thus effectively solving the worker shortage problem as well as the cold start issue.More importantly,we consider trust and security issues,and evaluate the trust and social circles of workers by accumulating task feedback,to provide the platform a reference for worker recruitment,thereby creating a high-quality worker pool.Finally,extensive simulations demonstrate ITTS outperforms two benchmark methods by increasing task completion rates by 56.49%-61.53%and profit by 42.34%-47.19%. 展开更多
关键词 Industrial Internet of Things Insufficient workers Trust evaluation Social relation Task assignment
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Mixed integer programming modeling for the satellite three-dimensional component assignment and layout optimization problem
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作者 Yufeng XIA Xianqi CHEN +3 位作者 Zhijia LIU Weien ZHOU Wen YAO Zhongneng ZHANG 《Chinese Journal of Aeronautics》 2025年第6期427-447,共21页
Satellite Component Layout Optimization(SCLO) is crucial in satellite system design.This paper proposes a novel Satellite Three-Dimensional Component Assignment and Layout Optimization(3D-SCALO) problem tailored to en... Satellite Component Layout Optimization(SCLO) is crucial in satellite system design.This paper proposes a novel Satellite Three-Dimensional Component Assignment and Layout Optimization(3D-SCALO) problem tailored to engineering requirements, aiming to optimize satellite heat dissipation while considering constraints on static stability, 3D geometric relationships between components, and special component positions. The 3D-SCALO problem is a challenging bilevel combinatorial optimization task, involving the optimization of discrete component assignment variables in the outer layer and continuous component position variables in the inner layer,with both influencing each other. To address this issue, first, a Mixed Integer Programming(MIP) model is proposed, which reformulates the original bilevel problem into a single-level optimization problem, enabling the exploration of a more comprehensive optimization space while avoiding iterative nested optimization. Then, to model the 3D geometric relationships between components within the MIP framework, a linearized 3D Phi-function method is proposed, which handles non-overlapping and safety distance constraints between cuboid components in an explicit and effective way. Subsequently, the Finite-Rectangle Method(FRM) is proposed to manage 3D geometric constraints for complex-shaped components by approximating them with a finite set of cuboids, extending the applicability of the geometric modeling approach. Finally, the feasibility and effectiveness of the proposed MIP model are demonstrated through two numerical examples"and a real-world engineering case, which confirms its suitability for complex-shaped components and real engineering applications. 展开更多
关键词 Mixed integer programming modeling Three-dimensional component assignment Layout optimization Phi-function Finite-rectangle method
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Current development and future prospects of multi-target assignment problem:A bibliometric analysis review
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作者 Shuangxi Liu Zehuai Lin +1 位作者 Wei Huang Binbin Yan 《Defence Technology(防务技术)》 2025年第1期44-59,共16页
The multi-target assignment(MTA)problem,a crucial challenge in command control,mission planning,and a fundamental research focus in military operations,has garnered significant attention over the years.Extensively stu... The multi-target assignment(MTA)problem,a crucial challenge in command control,mission planning,and a fundamental research focus in military operations,has garnered significant attention over the years.Extensively studied across various domains such as land,sea,air,space,and electronics,the MTA problem has led to the emergence of numerous models and algorithms.To delve deeper into this field,this paper starts by conducting a bibliometric analysis on 463 Scopus database papers using CiteSpace software.The analysis includes examining keyword clustering,co-occurrence,and burst,with visual representations of the results.Following this,the paper provides an overview of current classification and modeling techniques for addressing the MTA problem,distinguishing between static multi-target assignment(SMTA)and dynamic multi-target assignment(DMTA).Subsequently,existing solution algorithms for the MTA problem are reviewed,generally falling into three categories:exact algorithms,heuristic algorithms,and machine learning algorithms.Finally,a development framework is proposed based on the"HIGH"model(high-speed,integrated,great,harmonious)to guide future research and intelligent weapon system development concerning the MTA problem.This framework emphasizes application scenarios,modeling mechanisms,solution algorithms,and system efficiency to offer a roadmap for future exploration in this area. 展开更多
关键词 Multi-target assignment Offensive and defensive confrontation Cooperative operation Modeling mechanism Solution algorithm CiteSpace analysis
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Mixed parking demand assignment in hub parking lots based on regression modeling
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作者 ZHANG Chu CHEN Kehan +1 位作者 CHEN Jun CHEN Jiayi 《Journal of Southeast University(English Edition)》 2025年第3期270-277,共8页
To adapt to the unique demand-supply features of accessory parking lots at passenger transport hubs,a mixed parking demand assignment method based on regression modeling is proposed.First,an optimal model aiming to mi... To adapt to the unique demand-supply features of accessory parking lots at passenger transport hubs,a mixed parking demand assignment method based on regression modeling is proposed.First,an optimal model aiming to minimize total time expenditure is constructed.It incorporates parking search time,walking time,and departure time,focusing on short-term parking features.Then,the information dimensions that the parking lot can obtain are evaluated,and three assignment strategies based on three types of regression models-linear regression(LR),extreme gradient boosting(XGBoost),and multilayer perceptron(MLP)-are proposed.A parking process simulation model is built using the traffic simulation package SUMO to facilitate data collection,model training,and case studies.Finally,the performance of the three strategies is com-pared,revealing that the XGBoost-based strategy performs the best in case parking lots,which reduces time expendi-ture by 29.3%and 37.2%,respectively,compared with the MLP-based strategy and LR-based strategy.This method offers diverse options for practical parking manage-ment. 展开更多
关键词 parking areas assignment hub parking lot regression-based modeling extreme gradient boosting(XG-Boost)
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Weapon-target assignment for unmanned aerial vehicles: A multi-strategy threshold public goods game approach
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作者 Wenhao Bi Zhaoxi Wang +1 位作者 Yang Xu An Zhang 《Defence Technology(防务技术)》 2025年第6期221-237,共17页
As a crucial process in the coordinated strikes of unmanned aerial vehicles(UAVs), weapon-target assignment is vital for optimizing the allocation of available weapons and effectively exploiting the capabilities of UA... As a crucial process in the coordinated strikes of unmanned aerial vehicles(UAVs), weapon-target assignment is vital for optimizing the allocation of available weapons and effectively exploiting the capabilities of UAVs. Existing weapon-target assignment methods primarily focus on macro cluster constraints while neglecting individual strategy updates. This paper proposes a novel weapon-target assignment method for UAVs based on the multi-strategy threshold public goods game(PGG). By analyzing the concept mapping between weapon-target assignment for UAVs and multi-strategy threshold PGG, a weapon-target assignment model for UAVs based on the multi-strategy threshold PGG is established, which is adaptively complemented by the diverse cooperation-defection strategy library and the utility function based on the threshold mechanism. Additionally, a multi-chain Markov is formulated to quantitatively describe the stochastic evolutionary dynamics, whose evolutionary stable distribution is theoretically derived through the development of a strategy update rule based on preference-based aspiration dynamic. Numerical simulation results validate the feasibility and effectiveness of the proposed method, and the impacts of selection intensity, preference degree and threshold on the evolutionary stable distribution are analyzed. Comparative simulations show that the proposed method outperforms GWO, DE, and NSGA-II, achieving 17.18% higher expected utility than NSGA-II and reducing evolutionary stable times by 25% in large-scale scenario. 展开更多
关键词 Unmanned aerial vehicles(UAVs) Weapon-target assignment Public goods game(PGG) Multi-chain markov Strategy update rule
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Enhanced interconnection and damping assignment passivity-based control for PM synchronous motors
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作者 Mohamed Azzi Lotfi Baghli +2 位作者 Ehsan Jamshidpour Phatiphat Thounthong Noureddine Takorabet 《Global Energy Interconnection》 2025年第4期657-667,共11页
Permanent Magnet Synchronous Motors(PMSMs)are widely employed in high-performance drive applications due to their superior efficiency and dynamic capabilities.However,their control remains challenging owing to nonline... Permanent Magnet Synchronous Motors(PMSMs)are widely employed in high-performance drive applications due to their superior efficiency and dynamic capabilities.However,their control remains challenging owing to nonlinear dynamics,parameter variations,and unmeasurable external disturbances,particularly load torquefluctuations.This study proposes an enhanced Interconnection and Damp-ing Assignment Passivity-Based Control(IDA-PBC)scheme,formulated within the port-controlled Hamiltonian(PCH)framework,to address these limitations.A nonlinear disturbance observer is embedded to estimate and compensate,in real time,for lumped mis-matched disturbances arising from parameter uncertainties and external loads.Additionally,aflatness-based control strategy is employed to generate the desired current references within the nonlinear drive system,ensuring accurate tracking of time-varying speed commands.This integrated approach preserves the system’s energy-based structure,enabling systematic stability analysis while enhancing robustness.The proposed control architecture also maintains low complexity with a limited number of tunable parameters,facilitating practical implementation.Simulation and experimental results under various operating conditions demonstrate the effectiveness and robustness of the proposed method.Comparative analysis with conventional proportional-integral(PI)control and standard IDA-PBC strategies confirms its capability to handle disturbances and maintain dynamic performance. 展开更多
关键词 Hamiltonian energy control Interconnection and damping assignment passivity-based control IDA-PBC Motor drives Permanent-magnet synchronous machine(PMSM) Speed control
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Joint planning method for cross-domain unmanned swarm target assignment and mission trajectory
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作者 WANG Ning LIANG Xiaolong +2 位作者 LI Zhe HOU Yueqi YANG Aiwu 《Journal of Systems Engineering and Electronics》 2025年第3期736-753,共18页
Compared with single-domain unmanned swarms,cross-domain unmanned swarms continue to face new challenges in terms of platform performance and constraints.In this paper,a joint unmanned swarm target assignment and miss... Compared with single-domain unmanned swarms,cross-domain unmanned swarms continue to face new challenges in terms of platform performance and constraints.In this paper,a joint unmanned swarm target assignment and mission trajectory planning method is proposed to meet the requirements of cross-domain unmanned swarm mission planning.Firstly,the different performances of cross-domain heterogeneous platforms and mission requirements of targets are characterised by using a collection of operational resources.Secondly,an algorithmic framework for joint target assignment and mission trajectory planning is proposed,in which the initial planning of the trajectory is performed in the target assignment phase,while the trajectory is further optimised afterwards.Next,the estimation of the distribution algorithms is combined with the genetic algorithm to solve the objective function.Finally,the algorithm is numerically simulated by specific cases.Simulation results indicate that the proposed algorithm can perform effective task assignment and trajectory planning for cross-domain unmanned swarms.Furthermore,the solution performance of the hybrid estimation of distribution algorithm(EDA)-genetic algorithm(GA)algorithm is better than that of GA and EDA. 展开更多
关键词 cross-domain swarm unmanned system target assignment trajectory planning joint planning hybrid estimation of distribution algorithm(EDA)-genetic algorithm(GA)
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Traffic-aware static channel assignment algorithm in wireless mesh networks 被引量:1
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作者 陶军 柳津 +1 位作者 邵碧锐 刘智杰 《Journal of Southeast University(English Edition)》 EI CAS 2011年第4期370-374,共5页
A channel assignment algorithm with awareness of link traffic is proposed in multi-radio multi-channel wireless mesh networks. First, the physical interference model based on the signal-to-interference-plus-noise rati... A channel assignment algorithm with awareness of link traffic is proposed in multi-radio multi-channel wireless mesh networks. First, the physical interference model based on the signal-to-interference-plus-noise ratio and successful transmission condition is described. The model is more suitable for a wireless communication environment than other existing models. Secondly, a pure integer quadratic programming (PIQP) model is used to solve the channel assignment problem and improve the capacity of wireless mesh networks. Consequently, a traffic- aware static channel assignment algorithm(TASC) is designed. The algorithm adopts some network parameters, including the network connectivity, the limitation of the number of radios and the successful transmission conditions in wireless communications. The TASC algorithm can diminish network interference and increase the efficiency of channel assignment while keeping the connectivity of the network. Finally, the feasibility and effectivity of the channel assignment solution are illustrated by the simulation results. Compared witb similar algorithms, the proposed algorithm can increase the capacity of WMNs. 展开更多
关键词 multi-radio multi-channel wireless mesh network static channel assignment traffic-aware
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~1H and ^(13)C NMR Assignments for Amlodipine and Risperidone
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作者 杨春晖 李勤 +2 位作者 刘雪辉 赵兴凯 崔育新 《Journal of Chinese Pharmaceutical Sciences》 CAS 2004年第1期49-52,共4页
Aim To investigate the NMR spectroscopy of amlodipine and risperidone.Methods 1D NMR and 2D NMR experimental techniques of gCOSY, gHSQC and gHMBC were wsed. Results Theassignments of the ~1H and ^(13) C NMR data for t... Aim To investigate the NMR spectroscopy of amlodipine and risperidone.Methods 1D NMR and 2D NMR experimental techniques of gCOSY, gHSQC and gHMBC were wsed. Results Theassignments of the ~1H and ^(13) C NMR data for the two drugs were performed and confirmed by theevidence of J_(HF) and J_(CF). Conclusion The structures of amlodipine and risperidone wereconfirmed by careful analysis of regular 1D and 2D NMR spectroscopy. 展开更多
关键词 NMR assignment fluorine coupling AMLODIPINE RISPERIDONE
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A Discrete-Time Stochastic Traffic Assignment Model
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作者 王炜 朱中 曲大义 《Journal of Southeast University(English Edition)》 EI CAS 2001年第1期13-17,共5页
A discrete time stochastic traffic assignment model is proposed. The model provides a discrete time description of the variations of flows on a road network during a day or a peak period. The congestion effect at li... A discrete time stochastic traffic assignment model is proposed. The model provides a discrete time description of the variations of flows on a road network during a day or a peak period. The congestion effect at links and link junctions are taken into account. The first in first out principle is enforced on all links at all periods of the day. A stochastic user equilibrium assignment is achieved when the tripmaker is unable to find better travel alternatives. A computational procedure is also presented. 展开更多
关键词 stochastic user equilibrium traffic assignment discrete time traffic assignment
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Cross Point Assignment Algorithm Under Consideration of Very Long Nets
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作者 张轶谦 谢民 +1 位作者 洪先龙 蔡懿慈 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2002年第6期582-588,共7页
A cross point assignment algorithm is proposed under consideration of very long nets (LCPA).It is to consider not only the cost of connection between cross points and pins and the exclusive cost among cross points on ... A cross point assignment algorithm is proposed under consideration of very long nets (LCPA).It is to consider not only the cost of connection between cross points and pins and the exclusive cost among cross points on the boundary of a global routing cell,but also the cost of displacement among cross points of the same net.The experiment results show that the quality and speed in the following detailed routing are improved obviously,especially for very long nets. 展开更多
关键词 cross point assignment layout VLSI
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ACS-based resource assignment and task scheduling in grid
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作者 祁超 张璟 李军怀 《Journal of Southeast University(English Edition)》 EI CAS 2007年第3期451-454,共4页
To solve the deadlock problem of tasks that the interdependence between tasks fails to consider during the course of resource assignment and task scheduling based on the heuristics algorithm, an improved ant colony sy... To solve the deadlock problem of tasks that the interdependence between tasks fails to consider during the course of resource assignment and task scheduling based on the heuristics algorithm, an improved ant colony system (ACS) based algorithm is proposed. First, how to map the resource assignment and task scheduling (RATS) problem into the optimization selection problem of task resource assignment graph (TRAG) and to add the semaphore mechanism in the optimal TRAG to solve deadlocks are explained. Secondly, how to utilize the grid pheromone system model to realize the algorithm based on ACS is explicated. This refers to the construction of TRAG by the random selection of appropriate resources for each task by the user agent and the optimization of TRAG through the positive feedback and distributed parallel computing mechanism of the ACS. Simulation results show that the proposed algorithm is effective and efficient in solving the deadlock problem. 展开更多
关键词 GRID resource assignment task scheduling ant colony system (ACS) task resource assignment graph (TRAG) SEMAPHORE
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Lazy loading algorithm for traffic assignment of road networks under fixed charge condition
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作者 赵金宝 邓卫 《Journal of Southeast University(English Edition)》 EI CAS 2011年第2期185-187,共3页
The measures of path charge are important considerations in traffic assignment of road networks. Factors, such as travel time, fixed charge and traffic congestion which affect road users' choices of trip paths, are a... The measures of path charge are important considerations in traffic assignment of road networks. Factors, such as travel time, fixed charge and traffic congestion which affect road users' choices of trip paths, are analyzed. Travelers usually decide their trip paths based on their personal habits, preferences and the information at hand. By considering both deterministic and stochastic factors which affect the value of time (VOT) during the process of path choosing, a variational inequality model is proposed to describe the problem of traffic assignment. A lazy loading algorithm for traffic assignment is designed to solve the proposed model, and the calculation steps are given. Numerical experiment results show that compared with the all-or-nothing assignment, the proposed model and the algorithm can provide more optimal traffic assignments for road networks. The results of this study can be used to optimize traffic planning and management. 展开更多
关键词 traffic assignment road networks fixed charge lazy loading algorithm
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Direct computing methods for turn flows in traffic assignment
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作者 任刚 王炜 《Journal of Southeast University(English Edition)》 EI CAS 2005年第2期225-228,共4页
Two methods based on a slight modification of the regular traffic assignmentalgorithms are proposed to directly compute turn flows instead of estimating them from link flows orobtaining them by expanding the networks.... Two methods based on a slight modification of the regular traffic assignmentalgorithms are proposed to directly compute turn flows instead of estimating them from link flows orobtaining them by expanding the networks. The first one is designed on the path-turn incidencerelationship, and it is similar to the computational procedure of link flows. It applies to thetraffic assignment algorithms that can provide detailed path structures. The second utilizes thelink-turn incidence relationship and the conservation of flow on links, a law deriving from thisrelationship. It is actually an improved version of Dial's logit assignment algorithm. The proposedapproaches can avoid the shortcomings both of the estimation methods, e. g. Furness's model andFrator's model, and of the network-expanding method in precision, stability and computation scale.Finally, they are validated by numerical examples. 展开更多
关键词 turn flow traffic assignment Dial's algorithm directly computing method
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Survey of the research on dynamic weapon-target assignment problem 被引量:50
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作者 Cai Huaiping Liu Jingxu Chen Yingwu Wang Hao 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2006年第3期559-565,共7页
The basic concepts and models of weapon-target assignment (WTA) are introduced and the mathematical nature of the WTA models is also analyzed. A systematic survey of research on WTA problem is provided. The present ... The basic concepts and models of weapon-target assignment (WTA) are introduced and the mathematical nature of the WTA models is also analyzed. A systematic survey of research on WTA problem is provided. The present research on WTA is focused on models and algorithms. In the research on models of WTA, the static WTA models are mainly studied and the dynamic WTA models are not fully studied in deed. In the research on algorithms of WTA, the intelligent algorithms are often used to solve the WTA problem. The small scale of static WTA problems has been solved very well, however, the large scale of dynamic WTA problems has not been solved effectively so far. Finally, the characteristics of dynamic WTA are analyzed and directions for the future research on dynamic WTA are discussed. 展开更多
关键词 military operational research dynamic weapon-target assignment SURVEY firepower assignment decision making combination optimization.
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Strategies for Effective Comments on Students’ Written Assignments
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作者 任永东 《教师》 2014年第17期46-46,共1页
Abstract:Comments on students’assignments are important for English course.The loopholes in teachers’working schemes-comments of their students’written assignments are the clues around which the paper spreads.In th... Abstract:Comments on students’assignments are important for English course.The loopholes in teachers’working schemes-comments of their students’written assignments are the clues around which the paper spreads.In the process of teaching,some English teachers pay so much attention to the contents taught in class but ignore the comments on students’written assignments.Consequently,it is not applicable for students to correct their mistakes in time and they probably make the same mistakes repeatedly. 展开更多
关键词 英语学习 学习方法 阅读知识 阅读材料
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Cooperative task assignment of multiple heterogeneous unmanned aerial vehicles using a modifed genetic algorithm with multi-type genes 被引量:39
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作者 Deng Qibo Yu Jianqiao Wang Ningfei 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2013年第5期1238-1250,共13页
The task assignment problem of multiple heterogeneous unmanned aerial vehicles (UAVs), concerned with cooperative decision making and control, is studied in this paper. The heterogeneous vehicles have different oper... The task assignment problem of multiple heterogeneous unmanned aerial vehicles (UAVs), concerned with cooperative decision making and control, is studied in this paper. The heterogeneous vehicles have different operational capabilities and kinematic constraints, and carry limited resources (e.g., weapons) onboard. They are designated to perform multiple consecutive tasks cooperatively on multiple ground targets. The problem becomes much more complicated because of these terms of heterogeneity. In order to tackle the challenge, we modify the former genetic algorithm with multi-type genes to stochastically search a best solution. Genes of chromo- somes are different, and they are assorted into several types according to the tasks that must be performed on targets. Different types of genes are processed specifically in the improved genetic operators including initialization, crossover, and mutation. We also present a mirror representation of vehicles to deal with the limited resource constraint. Feasible chromosomes that vehicles could perform tasks using their limited resources under the assignment are created and evolved by genetic operators. The effect of the proposed algorithm is demonstrated in numerical simulations. The results show that it effectively provides good feasible solutions and finds an optimal one. 展开更多
关键词 Cooperative control Genetic algorithm Heterogeneous unmanned aerial vehicles Multi-type genes Task assignment
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Weapon target assignment problem satisfying expected damage probabilities based on ant colony algorithm 被引量:26
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作者 Wang Yanxia Qian Longjun Guo Zhi Ma Lifeng 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2008年第5期939-944,共6页
A weapon target assignment (WTA) model satisfying expected damage probabilities with an ant colony algorithm is proposed. In order to save armament resource and attack the targets effectively, the strategy of the we... A weapon target assignment (WTA) model satisfying expected damage probabilities with an ant colony algorithm is proposed. In order to save armament resource and attack the targets effectively, the strategy of the weapon assignment is that the target with greater threat degree has higher priority to be intercepted. The effect of this WTA model is not maximizing the damage probability but satisfying the whole assignment result. Ant colony algorithm has been successfully used in many fields, especially in combination optimization. The ant colony algorithm for this WTA problem is described by analyzing path selection, pheromone update, and tabu table update. The effectiveness of the model and the algorithm is demonstrated with an example. 展开更多
关键词 weapon target assignment ant colony algorithm optimization.
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Assignment and expression patterns of porcine muscle-specific isoform of phosphoglycerate mutase gene 被引量:5
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作者 Haifang Qiu Shuhong Zhao +2 位作者 Xuewen Xu Martine Yerle Bang Liu 《Journal of Genetics and Genomics》 SCIE CAS CSCD 北大核心 2008年第5期257-260,共4页
It has been reported that the muscle-specific isoform (type M, PGAM2) of phosphoglycerate mutase (PGAM) is a housekeeping enzyme; it catalyzes the conversion of 3-phosphoglycerate into 2-phosphoglycerate in the gl... It has been reported that the muscle-specific isoform (type M, PGAM2) of phosphoglycerate mutase (PGAM) is a housekeeping enzyme; it catalyzes the conversion of 3-phosphoglycerate into 2-phosphoglycerate in the glycolysis process to release energy. It is encoded by the Pgam2 gene. In this study, the cDNA of the porcine Pgam2 was cloned. This gene contains an open reading frame of 765 bp encoding a protein of 253 residues, and the predicted protein sequences share high similarity with other mammalians, 96% identity with humans, and 94% identity with mouse and rats. Pgam2 was mapped to SSC18q13-q21 by the RH panel. In this region, there are several QTLs, such as fat ratio, lean percentage, and diameter of muslce fiber, which affect meat production and quality. The reverse transcriptase-polymerase chain reaction revealed that the porcine Pgam2 gene was mainly expressed in the muscle tissue (skeletal muscle and cardiac muscle), and was expressed highly at skeletal muscle development stages (embryonic periods: 33, 65, and 90 days post-conception (dpo); postnatal pigs: 4 days and adult). This indicates that the Pgam2 gene plays an important role in muscle growth and development. In addition, it was demonstrated that PGAM2 locates both in cytoplasm and nuclei, and takes part in the glycometabolism process of cytoplasm and nuclei. 展开更多
关键词 assignment expression patterns subcellular localization PORCINE pgma2
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