For establishing the equation of the capacitive target detection accurately, the distributing characteristics of the charges on the bomb body with capacitance fuze were explored. Continuous charges were analyzed disp...For establishing the equation of the capacitive target detection accurately, the distributing characteristics of the charges on the bomb body with capacitance fuze were explored. Continuous charges were analyzed dispersively. Based on the Coulomb's law, the dynamic equilibrium equations of the inducing charges on the bomb body were set up. For the four cases of d 0/L (the ratio between the electrode distance and the bomb length), the curves of the charge's distribution were given. It was concluded that: ① the charge density decreases steadily from the end near the frontal electrode to the bomb tail; ② the declining rate of the density is governed by d 0/L , the larger the value of d 0/L ,the higher the declining rate, and vice versa.展开更多
To solve the technical cruxes of the conventional system in deep rock mass, an automatic testing system for hydraulic fracturing that includes a single tube for hydraulic loop, a pressure-relief valve, central-tubeles...To solve the technical cruxes of the conventional system in deep rock mass, an automatic testing system for hydraulic fracturing that includes a single tube for hydraulic loop, a pressure-relief valve, central-tubeless packers, and a multichannel real-time data acquisition system was used for in-situ stresses measurement at great depths （over 1000 m） in a coalfield in Juye of Northern China. The values and orientations of horizontal principal stresses were determined by the new system. The virgin stress field and its distributing law were decided by the linear regression from the logged 37 points in seven boreholes. Besides, the typical boreholes arranged in both the adjacent zone and far away zone of the faults were analyzed, respectively. The results show that a stress concentration phenomenon and a deflection in the orientation of the maximal horizontal stress exist in the adjacent zone of the faults, which further provides theoretical basis for design and optimization of mining.展开更多
The functionalization of living cells,both internally and externally,transforming them into microma-chines with specified functions,holds significant po-tential in fields such as biosensing,biocomputing,and intelligen...The functionalization of living cells,both internally and externally,transforming them into microma-chines with specified functions,holds significant po-tential in fields such as biosensing,biocomputing,and intelligent theranostics.However,due to the complexity and dynamic nature of living cells,it remains challenging to allocate exogenous function-al materials to specific locations within the cell or on its surface and maintain their positions stable for a reasonable period.Here,we devise a DNA-pro-grammed cargo distributing system(DCD),capable of distributing functional modules to the cell mem-brane or within the cell as needed.This system includes an amphiphilic DNA structure for determin-ing the destination of the cargo and a DNA connector carried on it for recognizing the DNA-encoded cargo.We test three different morphologies of amphiphilic DNA structures and find that their efficiencies in cell surface retention and cell internalization significantly varied,enabling the distribution of nanoparticle cargos on the cell membrane and within the cell in distinct proportions.Their positions can remain sta-ble for at least 6 h.Moreover,this allocation method shows specificity,which minimizes the deployment of mismatched cargo.This method provides new tools for the modular construction of cellular micro-machines.展开更多
To generate a neutron beam exhibiting a Maxwellian energy distribution with narrow emission angles for measuring the neutron capture reaction rates of the s-process nuclides,a monoenergetic 3.4 MeV proton beam produce...To generate a neutron beam exhibiting a Maxwellian energy distribution with narrow emission angles for measuring the neutron capture reaction rates of the s-process nuclides,a monoenergetic 3.4 MeV proton beam produced by the tandem-accelerator in the China Institute of Atomic Energy was utilized.The proton beam was first transmitted through a 60.5μm aluminum foil and then impinged on a natural LiF target to produce neutron beam via^(7)Li(p,n)7Be reaction.The quasi-Gaussian energy distribution of protons in the LiF target resulted in neutron energy spectra that agreed with a Maxwellian energy distribution at kT=(22±2)keV,which was achieved by integrating neutrons detected within an emission angle of 65.0°±2.6°using a ^(6)Li glass detector positioned at 65°relative to the proton beam direction.The narrow angular spread of the Maxwelliandistributed neutron beam enables direct measurement of neutron capture cross-sections for most s-process nuclides,overcoming previous experimental limitations associated with broad angular distributions.展开更多
In modern ZnO varistors,traditional aging mechanisms based on increased power consumption are no longer relevant due to reduced power consumption during DC aging.Prolonged exposure to both AC and DC voltages results i...In modern ZnO varistors,traditional aging mechanisms based on increased power consumption are no longer relevant due to reduced power consumption during DC aging.Prolonged exposure to both AC and DC voltages results in increased leakage current,decreased breakdown voltage,and lower nonlinearity,ultimately compromising their protective performance.To investigate the evolution in electrical properties during DC aging,this work developed a finite element model based on Voronoi networks and conducted accelerated aging tests on commercial varistors.Throughout the aging process,current-voltage characteristics and Schottky barrier parameters were measured and analyzed.The results indicate that when subjected to constant voltage,current flows through regions with larger grain sizes,forming discharge channels.As aging progresses,the current focus increases on these channels,leading to a decline in the varistor’s overall performance.Furthermore,analysis of the Schottky barrier parameters shows that the changes in electrical performance during aging are non-monotonic.These findings offer theoretical support for understanding the aging mechanisms and condition assessment of modern stable ZnO varistors.展开更多
Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges...Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges.There has been a lack of a comprehensive and multidimensional assessment to inform strategic conservation planning.Therefore,this study integrated 4 key biodiversity indices including species richness(SR),phylogenetic diversity(PD),threatened species richness(TSR),and endemic species richness(ESR)to map species diversity distribution patterns,identify conservation gaps,and elucidate their effects of climatic factors.This study revealed that species diversity shows a clear trend of decreasing from the western region to the eastern region of Tajikistan.The central–western mountains(specifically the Gissar-Darvasian and Zeravshanian regions)emerge as irreplaceable biodiversity hotspots.However,we found a severe spatial mismatch between these priority areas and the existing protected areas(PAs).Protection coverage for all hotspots was alarmingly low,ranging from 31.00%to 38.00%.Consequently,a critical 64.80%of integrated priority areas fall outside of the current PAs,representing a major conservation gap.This study identified precipitation seasonality and isothermality as the principal drivers,collectively explaining over 50.00%of the diversity variation and suggesting high vulnerability to hydrological shifts.Furthermore,we detected significant geographic sampling bias in the public biodiversity databases,with the most critical hotspot being systematically under-sampled.This study provides a robust scientific basis for conservation action,highlighting the urgent need to strategically expand PAs in the under-protected southwestern region and to mitigate critical sampling gaps through targeted data digitization and field surveys.These measures are indispensable for securing Tajikistan’s unique biodiversity and achieving the Kunming-Montreal Global Biodiversity Framework Target 3(“30×30 Protection”).展开更多
Objectives This study aimed to explore the lagged and cumulative effects of risk factors on disability in older adults using distributed lag non-linear models(DLNMs).Methods We utilized data from the China Health and ...Objectives This study aimed to explore the lagged and cumulative effects of risk factors on disability in older adults using distributed lag non-linear models(DLNMs).Methods We utilized data from the China Health and Retirement Longitudinal Study(CHARLS).After feature selection via Elastic Net Regularization,we applied DLNMs to evaluate the lagged effects of risk factors.Disability was defined as the presence of any difficulties in basic activities of daily living(BADL).The cumulative relative risk(CRR)was calculated by summing the lag-specific risk estimates,representing the cumulative disability risk over the specified lag period.Effect modifications and sensitivity analyses were also performed.Results This study included a total of 2,318 participants.Early-phase lag factors,such as the difficulty in stooping(CRR=3.58;95%CI:2.31-5.55;P<0.001)and walking(CRR=2.77;95%CI:1.39-5.55;P<0.001),exerted the strongest effects immediately upon occurrence.Mid-phase lag factors,such as arthritis(CRR=1.51;95%CI:1.10-2.06;P=0.001),showed a resurgence in disability risk within 2-3 years.Late-phase lag factors,including depressive symptoms(CRR=2.38;95%CI:1.30-4.35;P<0.001)and elevated systolic blood pressure(CRR=1.64;95%CI:1.06-2.79;P=0.02),exhibited significant long-term cumulative risks.Conversely,grip strength(CRR=0.80;95%CI:0.54-0.95;P=0.02)and social participation(CRR=0.89;95%CI:0.73-0.99;P=0.04)were significant protective factors.Conclusions The findings underscore the importance of tailored interventions that account for various lag characteristics of different factors to effectively mitigate disability risk.Future studies should explore the underlying biological and sociological mechanisms of these lagged effects,identify intervention strategies that target risk factors with different lagged patterns,and evaluate their effectiveness.展开更多
The Haoping 40 m radio telescope at the National Time Service Center,Chinese Academy of Sciences was built in 2014 and is primarily used to observe navigation satellites and pulsars.Since the first successful very lon...The Haoping 40 m radio telescope at the National Time Service Center,Chinese Academy of Sciences was built in 2014 and is primarily used to observe navigation satellites and pulsars.Since the first successful very long baseline interferometry(VLBI)observation of L-band radio source fringes in 2022,ten observations have been made so far.The stations involved in the observations include the Haoping 40 m radio telescope(Haoping),the Tianma 65 m radio telescope(Tianma),the Nanshan 26 m radio telescope(Urumqi),the Guizhou 500 m radio telescope(FAST),the Jilin 13 m radio telescope(Jilin),the Effelsberg 100 m radio telescope(Effelsberg),the Onsala 25 m radio telescope(Onsala),and the Chiang Mai 40 m radio telescope(Chiang Mai).This paper presents details on the specifications of the Haoping 40 m radio telescope,as well as the design of the VLBI experiment,the observation process,and the data processing.We also discuss the analysis of the fringe results involving the Haoping 40 m radio telescope,using Distributed FX Correlator to obtain excellent results.We confirm that the telescope is capable of participating in VLBI observations and performing specific data processing tasks.It can therefore play a greater role in future VLBI observations.展开更多
Nitrogen(N)and phosphorus(P)are essential nutrients and can significantly impact primary productivity of the ecosystem causing water environmental problems.However,their cycling mechanisms are not well understood in a...Nitrogen(N)and phosphorus(P)are essential nutrients and can significantly impact primary productivity of the ecosystem causing water environmental problems.However,their cycling mechanisms are not well understood in alpine mountains with climate change.Hence,94 samples of river water were collected from 2018 to 2020 in the headwaters of the Shule River Basin to assess the nutrients spatiotemporal distribution and combined ap-proach of water quality index to assess water quality and potential sources.The findings depict that high nutrient concentrations were found to coincide with snowmelt and glacial meltwater and rainfall recharge periods,while total flux peaked from June to September due to increased runoff.Notably,total nitrogen(TN)concentrations were significantly higher near the town,primarily attributed to the replenishment of nitrate(NO_(3)^(‒)-N)from live-stock manure.The high total P(TP)was near the glacier,which was attributed to the transportation of glacial sediments into the river,and pH was another critical factor.N was the primary nutrient limiting factor for the growth of phytoplankton in river water.Although the migration and transport of nutrients have altered with climate change,river water quality is good in alpine mountains based on an overall evaluation.These findings contribute to enriching nutrient datasets and highlight the importance of water resource management and water quality assessment in sensitive and fragile alpine mountains.展开更多
Central Asia is characterized by an arid climate and widespread desert distribution,with its sustainable development severely constrained by dust events.An objective understanding of the spatiotemporal patterns and dr...Central Asia is characterized by an arid climate and widespread desert distribution,with its sustainable development severely constrained by dust events.An objective understanding of the spatiotemporal patterns and driving forces of dust weather is highly important in this area.Based on the meteorological observations from 2000 to 2020,we examined the spatiotemporal characteristics of dust weather in the five Central Asian countries(Kazakhstan,Uzbekistan,Kyrgyzstan,Turkmenistan,and Tajikistan)via Theil-Sen trend analysis and Geodetector modeling method,quantitatively revealing the influence of environmental factors,such as temperature,precipitation,and vegetation,on the frequency of dust weather.The results showed that:(1)dust weather in Central Asia was mainly distributed in a large''dust belt''extending from west to east from northern part of the Caspian lowland desert,and concentrated in basins,plains,and other low-altitude areas.Strong dust weather mainly occurred in northern areas of the Aral Sea and southern edge of Central Asia,with a maximum annual frequency of 21.9%;(2)strong dust weather in Central Asia has fluctuated and slightly decreased since 2001.The highest frequency(1.1%)occurred in spring(from March to June);(3)from 2000 to 2020,changes such as spot shifting and shrinking occurred in the four main source areas(north of the Aral Sea,Kyzylkum Desert,Karakum Desert,and Garabogazköl Bay region),where sandstorms occurred in Central Asia,and northern Caspian lowland desert became the most important low-emission dust source in Central Asia;and(4)the combined effect of soil moisture and air temperature has the most significant influence on dust weather in Central Asia.This study provides a theoretical basis for sand prevention and sand control in Central Asia.In the future,Central Asia should focus on the rational utilization of land and water resources,and implement human interventions such as vegetation restoration and optimization of irrigation methods to curb further desertification in this area.展开更多
The World Journal of Gastroenterology Editorial Board Members are composed of 357 distinguished experts active in the relevant field,distributed in 46 countries/regions,including Italy(66),Japan(53),United States(31),...The World Journal of Gastroenterology Editorial Board Members are composed of 357 distinguished experts active in the relevant field,distributed in 46 countries/regions,including Italy(66),Japan(53),United States(31),China(29),South Korea(16),Spain(15),Australia(13),Greece(12),Brazil(11),Romania(8),Germany(7),India(7),Taiwan(7),United Kingdom(7),Türkiye(7),Hungary(5),Russia(5).展开更多
The intracontinental subduction of a>200-km-long section of the Tajik-Tarim lithosphere beneath the Pamir Mountains is proposed to explain nearly 30 km of shortening in the Tajik fold-thrust belt and the Pamir upli...The intracontinental subduction of a>200-km-long section of the Tajik-Tarim lithosphere beneath the Pamir Mountains is proposed to explain nearly 30 km of shortening in the Tajik fold-thrust belt and the Pamir uplift.Seismic imaging revealed that the upper slab was scraped and that the lower slab had subducted to a depth of>150 km.These features constitute the tectonic complexity of the Pamirs,as well as the thermal subduction mechanism involved,which remains poorly understood.Hence,in this study,high-resolution three-dimensional(3D)kinematic modeling is applied to investigate the thermal structure and geometry of the subducting slab beneath the Pamirs.The modeled slab configuration reveals distinct along-strike variations,with a steeply dipping slab beneath the southern Pamirs,a more gently inclined slab beneath the northern Pamirs,and apparent upper slab termination at shallow depths beneath the Pamirs.The thermal field reveals a cold slab core after delamination,with temperatures ranging from 400℃to 800℃,enveloped by a hotter mantle reaching~1400℃.The occurrence of intermediate-depth earthquakes aligns primarily with colder slab regions,particularly near the slab tear-off below the southwestern Pamirs,indicating a strong correlation between slab temperature and seismicity.In contrast,the northern Pamirs exhibit reduced seismicity at depth,which is likely associated with thermal weakening and delamination.The central Pamirs show a significant thermal anomaly caused by a concave slab,where the coldest crust does not descend deeply,further suggesting crustal detachment or mechanical failure.The lateral asymmetry in slab temperature possibly explains the mechanism of lateral tearing and differential slab-mantle coupling.展开更多
Giant kelp Macrocystis pyrifera,an important foundation species with great ecological and economic value,is threatened by climate change.To better understand the impact of climate warming on M.pyrifera,we investigated...Giant kelp Macrocystis pyrifera,an important foundation species with great ecological and economic value,is threatened by climate change.To better understand the impact of climate warming on M.pyrifera,we investigated its global distribution dynamics by an optimized species distribution model(SDM).Results showed that wave height,sea surface temperature,benthic temperature,and benthic phosphate concentration were key factors shaping the distribution of M.pyrifera.In addition to currently known distribution regions,the model revealed potential suitable habitats globally.Under future climate scenarios,the habitat suitability of M.pyrifera would decrease at low latitudes and increase at high latitudes,resulting in a poleward shift of suitable habitats.In the regions currently occupied by M.pyrifera,the high suitable habitats were predicted to shrink,which implies that the existing M.pyrifera would be adversely impacted.These results serve as references for the conservation and utilization of M.pyrifera resource.展开更多
This study investigates the mechanisms of friction-induced vibration under periodic variations in stress distribution using an improved fretting friction model.A fretting friction test system integrated with a total r...This study investigates the mechanisms of friction-induced vibration under periodic variations in stress distribution using an improved fretting friction model.A fretting friction test system integrated with a total reflection method was developed to analyze interfacial contact behavior under dynamic loading conditions.An improved fretting friction model was established,incorporating three critical nonlinear parameters:the hysteretic friction coefficient,tangential stiffness fluctuations,and stress distribution.Through systematic validation,the model demonstrates high-fidelity replication of experimental steady-state amplitude-frequency responses.Key findings reveal that non-uniform stress distribution governs irregularities in the vibration response,and increased uniformity intensifies stick-slip instabilities.Near the stick-slip transition threshold,distinct vibration anomalies emerge due to the coupled effects of stress heterogeneity,friction hysteresis,and stiffness variations during state transitions.Furthermore,the magnitude of the normal contact force systematically alters the dominant interfacial contact mechanism.The different interfacial contact states at various frequencies lead to distinct steady-state responses.This shift elevates resonance frequencies and amplifies higher-order resonant peaks.The fretting friction model provides a predictive framework for vibration control under dynamic interfacial loading.展开更多
With more and more IoT terminals being deployed in various power grid business scenarios,terminal reliability has become a practical challenge that threatens the current security protection architecture.Most IoT termi...With more and more IoT terminals being deployed in various power grid business scenarios,terminal reliability has become a practical challenge that threatens the current security protection architecture.Most IoT terminals have security risks and vulnerabilities,and limited resources make it impossible to deploy costly security protection methods on the terminal.In order to cope with these problems,this paper proposes a lightweight trust evaluation model TCL,which combines three network models,TCN,CNN,and LSTM,with stronger feature extraction capability and can score the reliability of the device by periodically analyzing the traffic behavior and activity logs generated by the terminal device,and the trust evaluation of the terminal’s continuous behavior can be achieved by combining the scores of different periods.After experiments,it is proved that TCL can effectively use the traffic behaviors and activity logs of terminal devices for trust evaluation and achieves F1-score of 95.763,94.456,99.923,and 99.195 on HDFS,BGL,N-BaIoT,and KDD99 datasets,respectively,and the size of TCL is only 91KB,which can achieve similar or better performance than CNN-LSTM,RobustLog and other methods with less computational resources and storage space.展开更多
Nereididae is a prolific annelid family widely distributed in the world oceans,especially in the Indo-Pacific Convergence Zone(IPCZ).However,its biogeographic pattern remains unexplored in IPCZ.To contribute to the un...Nereididae is a prolific annelid family widely distributed in the world oceans,especially in the Indo-Pacific Convergence Zone(IPCZ).However,its biogeographic pattern remains unexplored in IPCZ.To contribute to the understanding of biodiversity and biogeography of Nereididae in the IPCZ,we integrated historical data of species distributions with those of model-predicted ones to determine the biogeographic patterns of nereid species,from which we projected to its future distribution patterns for 2090-2100 under different climate scenarios(SSP1-1.9 and SSP5-8.5).Functional diversity within IPCZ was assessed using functional richness,functional evenness,and functional disparity.Divergence times within Nereididae were estimated using three DNA marker genes(COI,16S,and 18S rRNA),and a time tree was constructed based on a strict molecular clock model.The IPCZ was established as a key Nereididae biodiversity hotspot through distribution modelling of 256 species(44 genera),and temperature emerging as the predominant climatic driver of species distribution patterns.The distribution of species and functional diversity is notable for its non-centralized pattern.We projected that by the end of the century,areas of medium-to-high species richness will expand significantly under the low-emission SSP1-1.9 climate scenario.However,under the high-emission SSP5-8.5 scenario,the suitability of these regions significantly declines,posing an increasingly severe threat to biodiversity.In addition,by molecular clock analysis,we revealed that the evolutionary divergence of extant nereidid species occurred mainly in the Cretaceous and Jurassic,suggesting that paleogeographical and environmental events,such as oceanic anoxic events,might have played a pivotal role in shaping the evolutionary trajectory and ecological adaptations of marine annelids.These findings highlight the importance of considering both current biodiversity patterns and historical contexts in conservation planning,and provided insights into the potential factors on the biogeographic distribution and evolutionary processes of Nereididae.展开更多
Ensuring reliable power supply in urban distribution networks is a complex and critical task.To address the increased demand during extreme scenarios,this paper proposes an optimal dispatch strategy that considers the...Ensuring reliable power supply in urban distribution networks is a complex and critical task.To address the increased demand during extreme scenarios,this paper proposes an optimal dispatch strategy that considers the coordination with virtual power plants(VPPs).The proposed strategy improves systemflexibility and responsiveness by optimizing the power adjustment of flexible resources.In the proposed strategy,theGaussian Process Regression(GPR)is firstly employed to determine the adjustable range of aggregated power within the VPP,facilitating an assessment of its potential contribution to power supply support.Then,an optimal dispatch model based on a leader-follower game is developed to maximize the benefits of the VPP and flexible resources while guaranteeing the power balance at the same time.To solve the proposed optimal dispatch model efficiently,the constraints of the problem are reformulated and resolved using the Karush-Kuhn-Tucker(KKT)optimality conditions and linear programming duality theorem.The effectiveness of the strategy is illustrated through a detailed case study.展开更多
Coordinating light and nitrogen(N)distribution within a canopy is essential for improving rice yield and resource use efficiency.However,limited research has examined light and N distribution in response to planting d...Coordinating light and nitrogen(N)distribution within a canopy is essential for improving rice yield and resource use efficiency.However,limited research has examined light and N distribution in response to planting density and N rate,and their relationships with grain yield,radiation use efficiency(RUE),and N use efficiency for grain production(NUEg)in rice.A two-year field experiment was conducted with two hybrid varieties under three N levels,0 kg ha^(-1)(N1),90 kg ha^(-1)(N2)and 180 kg ha^(-1)(N3),and two planting densities,22.2 hills m-2(D1)and 33.3 hills m^(-2)(D2).Results showed 3.4%higher yield and 4.4%higher NUEg under N2D2 compared with N3D1.The extinction coefficient for N(K_(N))and light(K_(L))and their ratio(K_(N)/K_(L))at heading stage were significantly influenced by N rate,planting density,and their interaction.K_(N)decreased with the increase of N input or planting density.Compared to N1,K_(N)decreased by 43.5 and 58.8%under N2 and N3,respectively,while K_(N)under D2 decreased by 16.0%compared to D1.Higher K_(L)and K_(N)/K_(L)values occurred under low N rates,with opposite trends under high N rates.Increased planting density led to decreased K_(L)and K_(N)/K_(L)values.N2D2 demonstrated higher K_(L)and K_(N),and thus comparable K_(N)/K_(L),compared to N3D1.Correlation analysis revealed K_(L)negatively correlated with RUE,while K_(N)and K_(N)/K_(L)positively correlated with NUEg.These findings indicate that increasing planting density under reduced N input could maintain rice yield while enhancing resource use efficiency through regulation of canopy light and N distribution.展开更多
文摘For establishing the equation of the capacitive target detection accurately, the distributing characteristics of the charges on the bomb body with capacitance fuze were explored. Continuous charges were analyzed dispersively. Based on the Coulomb's law, the dynamic equilibrium equations of the inducing charges on the bomb body were set up. For the four cases of d 0/L (the ratio between the electrode distance and the bomb length), the curves of the charge's distribution were given. It was concluded that: ① the charge density decreases steadily from the end near the frontal electrode to the bomb tail; ② the declining rate of the density is governed by d 0/L , the larger the value of d 0/L ,the higher the declining rate, and vice versa.
基金This work was financially supported by the National Natural Science Foundation of China (No. 50490271)
文摘To solve the technical cruxes of the conventional system in deep rock mass, an automatic testing system for hydraulic fracturing that includes a single tube for hydraulic loop, a pressure-relief valve, central-tubeless packers, and a multichannel real-time data acquisition system was used for in-situ stresses measurement at great depths （over 1000 m） in a coalfield in Juye of Northern China. The values and orientations of horizontal principal stresses were determined by the new system. The virgin stress field and its distributing law were decided by the linear regression from the logged 37 points in seven boreholes. Besides, the typical boreholes arranged in both the adjacent zone and far away zone of the faults were analyzed, respectively. The results show that a stress concentration phenomenon and a deflection in the orientation of the maximal horizontal stress exist in the adjacent zone of the faults, which further provides theoretical basis for design and optimization of mining.
基金supported by the National Key R&D Program of China(grant no.2020YFA0908900)the National Natural Science Foundation of China(grant nos.22105124,22325406,21934007,21991134,T2188102)+1 种基金2022 Shanghai“Science and Technology Innovation Action Plan”Fundamental Research Project(grant no.22JC1401203)the New Cornerstone Science Foundation,and the Open Research Fund of the National Facility for Translational Medicine(Shanghai,grant no.TMSK-2021-412).
文摘The functionalization of living cells,both internally and externally,transforming them into microma-chines with specified functions,holds significant po-tential in fields such as biosensing,biocomputing,and intelligent theranostics.However,due to the complexity and dynamic nature of living cells,it remains challenging to allocate exogenous function-al materials to specific locations within the cell or on its surface and maintain their positions stable for a reasonable period.Here,we devise a DNA-pro-grammed cargo distributing system(DCD),capable of distributing functional modules to the cell mem-brane or within the cell as needed.This system includes an amphiphilic DNA structure for determin-ing the destination of the cargo and a DNA connector carried on it for recognizing the DNA-encoded cargo.We test three different morphologies of amphiphilic DNA structures and find that their efficiencies in cell surface retention and cell internalization significantly varied,enabling the distribution of nanoparticle cargos on the cell membrane and within the cell in distinct proportions.Their positions can remain sta-ble for at least 6 h.Moreover,this allocation method shows specificity,which minimizes the deployment of mismatched cargo.This method provides new tools for the modular construction of cellular micro-machines.
基金National Natural Science Foundation of China(12125509,11961141003,12275361,U2267205,12175152,12175121)National Key Research and Development Project(2022YFA1602301)Continuous-support Basic Scientific Research Project。
文摘To generate a neutron beam exhibiting a Maxwellian energy distribution with narrow emission angles for measuring the neutron capture reaction rates of the s-process nuclides,a monoenergetic 3.4 MeV proton beam produced by the tandem-accelerator in the China Institute of Atomic Energy was utilized.The proton beam was first transmitted through a 60.5μm aluminum foil and then impinged on a natural LiF target to produce neutron beam via^(7)Li(p,n)7Be reaction.The quasi-Gaussian energy distribution of protons in the LiF target resulted in neutron energy spectra that agreed with a Maxwellian energy distribution at kT=(22±2)keV,which was achieved by integrating neutrons detected within an emission angle of 65.0°±2.6°using a ^(6)Li glass detector positioned at 65°relative to the proton beam direction.The narrow angular spread of the Maxwelliandistributed neutron beam enables direct measurement of neutron capture cross-sections for most s-process nuclides,overcoming previous experimental limitations associated with broad angular distributions.
文摘In modern ZnO varistors,traditional aging mechanisms based on increased power consumption are no longer relevant due to reduced power consumption during DC aging.Prolonged exposure to both AC and DC voltages results in increased leakage current,decreased breakdown voltage,and lower nonlinearity,ultimately compromising their protective performance.To investigate the evolution in electrical properties during DC aging,this work developed a finite element model based on Voronoi networks and conducted accelerated aging tests on commercial varistors.Throughout the aging process,current-voltage characteristics and Schottky barrier parameters were measured and analyzed.The results indicate that when subjected to constant voltage,current flows through regions with larger grain sizes,forming discharge channels.As aging progresses,the current focus increases on these channels,leading to a decline in the varistor’s overall performance.Furthermore,analysis of the Schottky barrier parameters shows that the changes in electrical performance during aging are non-monotonic.These findings offer theoretical support for understanding the aging mechanisms and condition assessment of modern stable ZnO varistors.
基金the Chinese Academy of Sciences Research Center for Ecology and Environment of Central Asia(RCEECA),the construction and joint research for the China-Tajikistan“Belt and Road”Joint Laboratory on Biodiversity Conservation and Sustainable Use(2024YFE0214200)the Shanghai Cooperation Organization Partnership and International Technology Cooperation Plan of Science and Technology Projects(2023E01018,2025E01056)the Chinese Academy of Sciences President’s International Fellowship Initiative(PIFI)(2024VBC0006).
文摘Tajikistan represents a core region of the biodiversity hotspot in Central Asian mountains and has exceptional vascular plant diversity.However,the species diversity of the country faces urgent conservation challenges.There has been a lack of a comprehensive and multidimensional assessment to inform strategic conservation planning.Therefore,this study integrated 4 key biodiversity indices including species richness(SR),phylogenetic diversity(PD),threatened species richness(TSR),and endemic species richness(ESR)to map species diversity distribution patterns,identify conservation gaps,and elucidate their effects of climatic factors.This study revealed that species diversity shows a clear trend of decreasing from the western region to the eastern region of Tajikistan.The central–western mountains(specifically the Gissar-Darvasian and Zeravshanian regions)emerge as irreplaceable biodiversity hotspots.However,we found a severe spatial mismatch between these priority areas and the existing protected areas(PAs).Protection coverage for all hotspots was alarmingly low,ranging from 31.00%to 38.00%.Consequently,a critical 64.80%of integrated priority areas fall outside of the current PAs,representing a major conservation gap.This study identified precipitation seasonality and isothermality as the principal drivers,collectively explaining over 50.00%of the diversity variation and suggesting high vulnerability to hydrological shifts.Furthermore,we detected significant geographic sampling bias in the public biodiversity databases,with the most critical hotspot being systematically under-sampled.This study provides a robust scientific basis for conservation action,highlighting the urgent need to strategically expand PAs in the under-protected southwestern region and to mitigate critical sampling gaps through targeted data digitization and field surveys.These measures are indispensable for securing Tajikistan’s unique biodiversity and achieving the Kunming-Montreal Global Biodiversity Framework Target 3(“30×30 Protection”).
基金supported by ScientificResearch Fund of National Health Commission of the People’s Republic of China-Major Science and Technology Program for Medicine and Health in Zhejiang Province(WKJ-ZJ-2406).
文摘Objectives This study aimed to explore the lagged and cumulative effects of risk factors on disability in older adults using distributed lag non-linear models(DLNMs).Methods We utilized data from the China Health and Retirement Longitudinal Study(CHARLS).After feature selection via Elastic Net Regularization,we applied DLNMs to evaluate the lagged effects of risk factors.Disability was defined as the presence of any difficulties in basic activities of daily living(BADL).The cumulative relative risk(CRR)was calculated by summing the lag-specific risk estimates,representing the cumulative disability risk over the specified lag period.Effect modifications and sensitivity analyses were also performed.Results This study included a total of 2,318 participants.Early-phase lag factors,such as the difficulty in stooping(CRR=3.58;95%CI:2.31-5.55;P<0.001)and walking(CRR=2.77;95%CI:1.39-5.55;P<0.001),exerted the strongest effects immediately upon occurrence.Mid-phase lag factors,such as arthritis(CRR=1.51;95%CI:1.10-2.06;P=0.001),showed a resurgence in disability risk within 2-3 years.Late-phase lag factors,including depressive symptoms(CRR=2.38;95%CI:1.30-4.35;P<0.001)and elevated systolic blood pressure(CRR=1.64;95%CI:1.06-2.79;P=0.02),exhibited significant long-term cumulative risks.Conversely,grip strength(CRR=0.80;95%CI:0.54-0.95;P=0.02)and social participation(CRR=0.89;95%CI:0.73-0.99;P=0.04)were significant protective factors.Conclusions The findings underscore the importance of tailored interventions that account for various lag characteristics of different factors to effectively mitigate disability risk.Future studies should explore the underlying biological and sociological mechanisms of these lagged effects,identify intervention strategies that target risk factors with different lagged patterns,and evaluate their effectiveness.
基金supported by the National Science and Technology Major Project(E152KJ1201)the Natural Science Basic Research Program of Shaanxi(2024JC-YBQN-0036)+1 种基金the National Natural Science Foundation of China(42030105 and 11973046)the National SKA Program of China(2020SKA0120200).
文摘The Haoping 40 m radio telescope at the National Time Service Center,Chinese Academy of Sciences was built in 2014 and is primarily used to observe navigation satellites and pulsars.Since the first successful very long baseline interferometry(VLBI)observation of L-band radio source fringes in 2022,ten observations have been made so far.The stations involved in the observations include the Haoping 40 m radio telescope(Haoping),the Tianma 65 m radio telescope(Tianma),the Nanshan 26 m radio telescope(Urumqi),the Guizhou 500 m radio telescope(FAST),the Jilin 13 m radio telescope(Jilin),the Effelsberg 100 m radio telescope(Effelsberg),the Onsala 25 m radio telescope(Onsala),and the Chiang Mai 40 m radio telescope(Chiang Mai).This paper presents details on the specifications of the Haoping 40 m radio telescope,as well as the design of the VLBI experiment,the observation process,and the data processing.We also discuss the analysis of the fringe results involving the Haoping 40 m radio telescope,using Distributed FX Correlator to obtain excellent results.We confirm that the telescope is capable of participating in VLBI observations and performing specific data processing tasks.It can therefore play a greater role in future VLBI observations.
基金supported by the Second Tibetan Plateau Scientific Expedition and Research Program(STEP)(No.2019QZKK0208)the National Natural Science Foundation of China(Nos.42171148 and 42330512)the Key R&D Project from the Science and Technology Department of Tibet(No.XZ202501ZY0030).
文摘Nitrogen(N)and phosphorus(P)are essential nutrients and can significantly impact primary productivity of the ecosystem causing water environmental problems.However,their cycling mechanisms are not well understood in alpine mountains with climate change.Hence,94 samples of river water were collected from 2018 to 2020 in the headwaters of the Shule River Basin to assess the nutrients spatiotemporal distribution and combined ap-proach of water quality index to assess water quality and potential sources.The findings depict that high nutrient concentrations were found to coincide with snowmelt and glacial meltwater and rainfall recharge periods,while total flux peaked from June to September due to increased runoff.Notably,total nitrogen(TN)concentrations were significantly higher near the town,primarily attributed to the replenishment of nitrate(NO_(3)^(‒)-N)from live-stock manure.The high total P(TP)was near the glacier,which was attributed to the transportation of glacial sediments into the river,and pH was another critical factor.N was the primary nutrient limiting factor for the growth of phytoplankton in river water.Although the migration and transport of nutrients have altered with climate change,river water quality is good in alpine mountains based on an overall evaluation.These findings contribute to enriching nutrient datasets and highlight the importance of water resource management and water quality assessment in sensitive and fragile alpine mountains.
基金funded by the National Natural Science Foundation of China(42571311).
文摘Central Asia is characterized by an arid climate and widespread desert distribution,with its sustainable development severely constrained by dust events.An objective understanding of the spatiotemporal patterns and driving forces of dust weather is highly important in this area.Based on the meteorological observations from 2000 to 2020,we examined the spatiotemporal characteristics of dust weather in the five Central Asian countries(Kazakhstan,Uzbekistan,Kyrgyzstan,Turkmenistan,and Tajikistan)via Theil-Sen trend analysis and Geodetector modeling method,quantitatively revealing the influence of environmental factors,such as temperature,precipitation,and vegetation,on the frequency of dust weather.The results showed that:(1)dust weather in Central Asia was mainly distributed in a large''dust belt''extending from west to east from northern part of the Caspian lowland desert,and concentrated in basins,plains,and other low-altitude areas.Strong dust weather mainly occurred in northern areas of the Aral Sea and southern edge of Central Asia,with a maximum annual frequency of 21.9%;(2)strong dust weather in Central Asia has fluctuated and slightly decreased since 2001.The highest frequency(1.1%)occurred in spring(from March to June);(3)from 2000 to 2020,changes such as spot shifting and shrinking occurred in the four main source areas(north of the Aral Sea,Kyzylkum Desert,Karakum Desert,and Garabogazköl Bay region),where sandstorms occurred in Central Asia,and northern Caspian lowland desert became the most important low-emission dust source in Central Asia;and(4)the combined effect of soil moisture and air temperature has the most significant influence on dust weather in Central Asia.This study provides a theoretical basis for sand prevention and sand control in Central Asia.In the future,Central Asia should focus on the rational utilization of land and water resources,and implement human interventions such as vegetation restoration and optimization of irrigation methods to curb further desertification in this area.
文摘The World Journal of Gastroenterology Editorial Board Members are composed of 357 distinguished experts active in the relevant field,distributed in 46 countries/regions,including Italy(66),Japan(53),United States(31),China(29),South Korea(16),Spain(15),Australia(13),Greece(12),Brazil(11),Romania(8),Germany(7),India(7),Taiwan(7),United Kingdom(7),Türkiye(7),Hungary(5),Russia(5).
基金the Chinese Academy of Sciences Pioneer Hundred Talents Program and the Second Tibetan Plateau Scientific Expedition and Research Program(Grant No.2019QZKK0708)supported by a MEXT(Ministry of Education,Culture,Sports,Science and Technology)KAKENHI(Grants-in-Aid for Scientific Research)grant(Grant No.21H05203)Kobe University Strategic International Collaborative Research Grant(Type B Fostering Joint Research).
文摘The intracontinental subduction of a>200-km-long section of the Tajik-Tarim lithosphere beneath the Pamir Mountains is proposed to explain nearly 30 km of shortening in the Tajik fold-thrust belt and the Pamir uplift.Seismic imaging revealed that the upper slab was scraped and that the lower slab had subducted to a depth of>150 km.These features constitute the tectonic complexity of the Pamirs,as well as the thermal subduction mechanism involved,which remains poorly understood.Hence,in this study,high-resolution three-dimensional(3D)kinematic modeling is applied to investigate the thermal structure and geometry of the subducting slab beneath the Pamirs.The modeled slab configuration reveals distinct along-strike variations,with a steeply dipping slab beneath the southern Pamirs,a more gently inclined slab beneath the northern Pamirs,and apparent upper slab termination at shallow depths beneath the Pamirs.The thermal field reveals a cold slab core after delamination,with temperatures ranging from 400℃to 800℃,enveloped by a hotter mantle reaching~1400℃.The occurrence of intermediate-depth earthquakes aligns primarily with colder slab regions,particularly near the slab tear-off below the southwestern Pamirs,indicating a strong correlation between slab temperature and seismicity.In contrast,the northern Pamirs exhibit reduced seismicity at depth,which is likely associated with thermal weakening and delamination.The central Pamirs show a significant thermal anomaly caused by a concave slab,where the coldest crust does not descend deeply,further suggesting crustal detachment or mechanical failure.The lateral asymmetry in slab temperature possibly explains the mechanism of lateral tearing and differential slab-mantle coupling.
基金Supported by the National Key Research and Development Program of China(No.2023YFD2400800)the Laoshan Laboratory(Nos.LSKJ202203801,LSKJ202203204)+4 种基金the Natural Science Foundation of Shandong Province(Nos.ZR2023MD127,ZR2021MD075)the Central Public-interest Scientific Institution Basal Research Fund CAFS(Nos.2023TD28,20603022023012)the National Natural Science Foundation of China(No.32373107)the China Agriculture Research System(No.CARS-50)the Taishan Scholars Program。
文摘Giant kelp Macrocystis pyrifera,an important foundation species with great ecological and economic value,is threatened by climate change.To better understand the impact of climate warming on M.pyrifera,we investigated its global distribution dynamics by an optimized species distribution model(SDM).Results showed that wave height,sea surface temperature,benthic temperature,and benthic phosphate concentration were key factors shaping the distribution of M.pyrifera.In addition to currently known distribution regions,the model revealed potential suitable habitats globally.Under future climate scenarios,the habitat suitability of M.pyrifera would decrease at low latitudes and increase at high latitudes,resulting in a poleward shift of suitable habitats.In the regions currently occupied by M.pyrifera,the high suitable habitats were predicted to shrink,which implies that the existing M.pyrifera would be adversely impacted.These results serve as references for the conservation and utilization of M.pyrifera resource.
基金Project supported by the National Natural Science Foundation of China(Grant No.11872033)the Beijing Natural Science Foundation,China(Grant No.3172017)。
文摘This study investigates the mechanisms of friction-induced vibration under periodic variations in stress distribution using an improved fretting friction model.A fretting friction test system integrated with a total reflection method was developed to analyze interfacial contact behavior under dynamic loading conditions.An improved fretting friction model was established,incorporating three critical nonlinear parameters:the hysteretic friction coefficient,tangential stiffness fluctuations,and stress distribution.Through systematic validation,the model demonstrates high-fidelity replication of experimental steady-state amplitude-frequency responses.Key findings reveal that non-uniform stress distribution governs irregularities in the vibration response,and increased uniformity intensifies stick-slip instabilities.Near the stick-slip transition threshold,distinct vibration anomalies emerge due to the coupled effects of stress heterogeneity,friction hysteresis,and stiffness variations during state transitions.Furthermore,the magnitude of the normal contact force systematically alters the dominant interfacial contact mechanism.The different interfacial contact states at various frequencies lead to distinct steady-state responses.This shift elevates resonance frequencies and amplifies higher-order resonant peaks.The fretting friction model provides a predictive framework for vibration control under dynamic interfacial loading.
基金supported by National Key R&D Program of China(No.2022YFB3105101).
文摘With more and more IoT terminals being deployed in various power grid business scenarios,terminal reliability has become a practical challenge that threatens the current security protection architecture.Most IoT terminals have security risks and vulnerabilities,and limited resources make it impossible to deploy costly security protection methods on the terminal.In order to cope with these problems,this paper proposes a lightweight trust evaluation model TCL,which combines three network models,TCN,CNN,and LSTM,with stronger feature extraction capability and can score the reliability of the device by periodically analyzing the traffic behavior and activity logs generated by the terminal device,and the trust evaluation of the terminal’s continuous behavior can be achieved by combining the scores of different periods.After experiments,it is proved that TCL can effectively use the traffic behaviors and activity logs of terminal devices for trust evaluation and achieves F1-score of 95.763,94.456,99.923,and 99.195 on HDFS,BGL,N-BaIoT,and KDD99 datasets,respectively,and the size of TCL is only 91KB,which can achieve similar or better performance than CNN-LSTM,RobustLog and other methods with less computational resources and storage space.
基金Supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB42000000)the National Natural Science Foundation of China(No.42376092)the Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology(No.2022QNLM030004)。
文摘Nereididae is a prolific annelid family widely distributed in the world oceans,especially in the Indo-Pacific Convergence Zone(IPCZ).However,its biogeographic pattern remains unexplored in IPCZ.To contribute to the understanding of biodiversity and biogeography of Nereididae in the IPCZ,we integrated historical data of species distributions with those of model-predicted ones to determine the biogeographic patterns of nereid species,from which we projected to its future distribution patterns for 2090-2100 under different climate scenarios(SSP1-1.9 and SSP5-8.5).Functional diversity within IPCZ was assessed using functional richness,functional evenness,and functional disparity.Divergence times within Nereididae were estimated using three DNA marker genes(COI,16S,and 18S rRNA),and a time tree was constructed based on a strict molecular clock model.The IPCZ was established as a key Nereididae biodiversity hotspot through distribution modelling of 256 species(44 genera),and temperature emerging as the predominant climatic driver of species distribution patterns.The distribution of species and functional diversity is notable for its non-centralized pattern.We projected that by the end of the century,areas of medium-to-high species richness will expand significantly under the low-emission SSP1-1.9 climate scenario.However,under the high-emission SSP5-8.5 scenario,the suitability of these regions significantly declines,posing an increasingly severe threat to biodiversity.In addition,by molecular clock analysis,we revealed that the evolutionary divergence of extant nereidid species occurred mainly in the Cretaceous and Jurassic,suggesting that paleogeographical and environmental events,such as oceanic anoxic events,might have played a pivotal role in shaping the evolutionary trajectory and ecological adaptations of marine annelids.These findings highlight the importance of considering both current biodiversity patterns and historical contexts in conservation planning,and provided insights into the potential factors on the biogeographic distribution and evolutionary processes of Nereididae.
基金supported by the Science and Technology Project of Sichuan Electric Power Company“Power Supply Guarantee Strategy for Urban Distribution Networks Considering Coordination with Virtual Power Plant during Extreme Weather Event”(No.521920230003).
文摘Ensuring reliable power supply in urban distribution networks is a complex and critical task.To address the increased demand during extreme scenarios,this paper proposes an optimal dispatch strategy that considers the coordination with virtual power plants(VPPs).The proposed strategy improves systemflexibility and responsiveness by optimizing the power adjustment of flexible resources.In the proposed strategy,theGaussian Process Regression(GPR)is firstly employed to determine the adjustable range of aggregated power within the VPP,facilitating an assessment of its potential contribution to power supply support.Then,an optimal dispatch model based on a leader-follower game is developed to maximize the benefits of the VPP and flexible resources while guaranteeing the power balance at the same time.To solve the proposed optimal dispatch model efficiently,the constraints of the problem are reformulated and resolved using the Karush-Kuhn-Tucker(KKT)optimality conditions and linear programming duality theorem.The effectiveness of the strategy is illustrated through a detailed case study.
基金supported by the Hubei Provincial Science and Technology Project,China(2025CSA039)the National Natural Science Foundation of China(32001467)。
文摘Coordinating light and nitrogen(N)distribution within a canopy is essential for improving rice yield and resource use efficiency.However,limited research has examined light and N distribution in response to planting density and N rate,and their relationships with grain yield,radiation use efficiency(RUE),and N use efficiency for grain production(NUEg)in rice.A two-year field experiment was conducted with two hybrid varieties under three N levels,0 kg ha^(-1)(N1),90 kg ha^(-1)(N2)and 180 kg ha^(-1)(N3),and two planting densities,22.2 hills m-2(D1)and 33.3 hills m^(-2)(D2).Results showed 3.4%higher yield and 4.4%higher NUEg under N2D2 compared with N3D1.The extinction coefficient for N(K_(N))and light(K_(L))and their ratio(K_(N)/K_(L))at heading stage were significantly influenced by N rate,planting density,and their interaction.K_(N)decreased with the increase of N input or planting density.Compared to N1,K_(N)decreased by 43.5 and 58.8%under N2 and N3,respectively,while K_(N)under D2 decreased by 16.0%compared to D1.Higher K_(L)and K_(N)/K_(L)values occurred under low N rates,with opposite trends under high N rates.Increased planting density led to decreased K_(L)and K_(N)/K_(L)values.N2D2 demonstrated higher K_(L)and K_(N),and thus comparable K_(N)/K_(L),compared to N3D1.Correlation analysis revealed K_(L)negatively correlated with RUE,while K_(N)and K_(N)/K_(L)positively correlated with NUEg.These findings indicate that increasing planting density under reduced N input could maintain rice yield while enhancing resource use efficiency through regulation of canopy light and N distribution.
