Growing literature has demonstrated that exercise may be an effective prevention and treatment option for drug addiction. In the past few years, many studies have suggested that there were sex differences in all phase...Growing literature has demonstrated that exercise may be an effective prevention and treatment option for drug addiction. In the past few years, many studies have suggested that there were sex differences in all phases of drug addiction. However, very limited research has investigated sex differences in the effectiveness of exercise intervention in drug addiction and rehabilitation. In this mini review, we summarize the effect of sex on the results of using exercise to prevent and treat drug addiction. The studies we consider span various animal models and use multiple types of exercise to examine the effectiveness of exercise on the neurobiological mechanism of exercise rehabilitation. We believe that exercise as an adjuvant intervention strategy can be applied better in drug addiction prevention and recovery. Copyright 2014, Shanghai University of Sport. Production and hosting by Elsevier B.V. All rights reserved.展开更多
Objective To observe the efficacy of combining therapy in treatment of 90 patients with scapulohumeral periarthritis in different phases. Method Ninety patients with scapulohumeral periarthritis were treated with Fu＇...Objective To observe the efficacy of combining therapy in treatment of 90 patients with scapulohumeral periarthritis in different phases. Method Ninety patients with scapulohumeral periarthritis were treated with Fu＇s subcutaneous needling（FSN） combined with physiotherapy in painful phase, acupotomology and massage in adhesion phase, and appropriate functional exercise in rehabilitation phase. Seven days were considered as one course of treatment, and efficacy evaluation was performed after three courses. Function evaluation of shoulder joint was made. Result The total effective rate was 100%（38/38） in acute phase, 93.5%（29/31） in adhesion phase, and 100%（21/21） in rehabilitation phase. After treatment, the range of motion（ROM） of shoulder joint, pain, muscle force, activities of daily living（ADL） and joint local morphology of the patient have been improved obviously. Conclusion Better clinical efficacy is achieved in treatment of scapulohumeral periarthritis in different phases by combining therapy centering on FSN.展开更多
Background:Acute mountain sickness(AMS)is the mildest form of acute altitude illnesses,and consists of nonspecific symptoms when unacclimatized persons ascend to elevation of≥2500 m.Risk factors of AMS include:the al...Background:Acute mountain sickness(AMS)is the mildest form of acute altitude illnesses,and consists of nonspecific symptoms when unacclimatized persons ascend to elevation of≥2500 m.Risk factors of AMS include:the altitude,individual susceptibility,ascending rate and degree of pre-acclimatization.In the current study,we examined whether physiological response at low altitude could predict the development of AMS.Methods:A total of 111 healthy adult healthy volunteers participated in this trial;and 99(67 men and 32 women)completed the entire study protocol.Subjects were asked to complete a 9-min exercise program using a mechanically braked bicycle ergometer at low altitude(500 m).Heart rate,blood pressure(BP)and pulse oxygen saturation(SpO2)were recorded prior to and during the last minute of exercise.The ascent from 500 m to 4100 m was completed in 2 days.AMS was defined as≥3 points in a 4-item Lake Louise Score,with at least one point from headache wat 6–8 h after the ascent.Results:Among the 99 assessable subjects,47(23 men and 24 women)developed AMS at 4100 m.In comparison to the subjects without AMS,those who developed AMS had lower proportion of men(48.9%vs.84.6%,P<0.001),height(168.4±5.9 cm vs.171.3±6.1 cm,P=0.019),weight(62.0±10.0 kg vs.66.7±8.6 kg,P=0.014)and proportion of smokers(23.4%vs.51.9%,P=0.004).Multivariate regression analysis revealed the following independent risks for AMS:female sex(odds ratio(OR)=6.32,P<0.001),SpO2 change upon exercise at low altitude(OR=0.63,P=0.002)and systolic BP change after the ascent(OR=0.96,P=0.029).Women had larger reduction in SpO2 after the ascent,higher AMS percentage and absolute AMS score.Larger reduction of SpO2 after exercise was associated with both AMS incidence(P=0.001)and AMS score(P<0.001)in men but not in women.Conclusions:Larger SpO2 reduction after exercise at low altitude was an independent risk for AMS upon ascent.Such an association was more robust in men than in women.Trial registration:Chinese Clinical Trial Registration,ChiCTR1900025728.Registered 6 September 2019.展开更多
As mental health issues among adolescents receive increasing attention,the impact of physical exercise on mental health has become prominent.In this paper,junior high school students in Luoding County and Yunan County...As mental health issues among adolescents receive increasing attention,the impact of physical exercise on mental health has become prominent.In this paper,junior high school students in Luoding County and Yunan County of Yunfu are taken as participants.It employs a convenient sampling method to distribute questionnaires,utilizes relevant scales for measurement,and analyzes the data with the assistance of SPSS 26.0.The results indicate a significantly negative correlation between physical exercise and social anxiety.Overall,junior high school students in this region engage in relatively weak physical exercise,and their social anxiety is at a moderate level,with female students being more prone to anxiety.Left-behind children exhibit higher levels of social anxiety compared to non-left-behind children.There are notable differences among group characteristics,with social and cultural factors and physiological factors influencing gender differences,and the lack of family support affecting the social anxiety of left-behind children.This study provides a basis for intervening in psychological anxiety and other issues.It is suggested deepening the sports collaborative education mechanism,paying attention to the cultivation of social and emotional abilities of left-behind children,and using physical exercise to promote the development of students social adaptability.展开更多
Purpose: Obtaining high peak bone mass (PBM) and maintaining bone mass is important for the prevention of osteoporosis. This study aimed to examine the regional differences in bone mineral density and factors associat...Purpose: Obtaining high peak bone mass (PBM) and maintaining bone mass is important for the prevention of osteoporosis. This study aimed to examine the regional differences in bone mineral density and factors associated with its acquisition from exercise. Design: The study population included 75 women of 18 - 22 years of age in East Japan and 104 women of 18 - 27 years of age in West Japan. The speed of sound (SOS) of the calcaneus was measured, and the young adult mean (%YAM) was calculated from the SOS. The subjects’ medical history, family history of osteoporosis, and exercise habits were examined using a self-administered questionnaire. Results: There were a significantly greater number of subjects with low %YAM in West Japan. The exercise history and exercise time were significantly higher in West Japan, and the exercise intensity score tended to be higher in East Japan during junior high and high school. A multiple regression analysis by region revealed that the following factors had a significant positive association with the SOS: exercise intensity at elementary school and outdoor sports at junior high school in East Japan;and exercise time at elementary school, muscle mass, and outdoor sports at junior high school in West Japan. On the other hand, exercise time in junior high school in West Japan showed a negative association with the SOS. Conclusions: Regional differences in bone mineral density existed, suggesting a trend toward lower bone mineral density in West Japan. Exercise history and time tended to be higher in West Japan, and exercise intensity scores tended to be higher in East Japan, suggesting that exercise intensity may be more important than exercise time for obtaining bone mineral density.展开更多
Background:Integrating metabolomics in sports science provides valuable insights into the biochemistry of bodies during physical activity.However,due to their invasiveness,traditional blood sampling methods present ch...Background:Integrating metabolomics in sports science provides valuable insights into the biochemistry of bodies during physical activity.However,due to their invasiveness,traditional blood sampling methods present challenges in sports settings.The study investigated sex-specific metabolic responses,addressing a significant gap in exercise research,where female participation remains underrepresented.Methods:To address this,we explored volumetrically accurate microsampling as a dried blood spot(DBS)technique for assessing metabolomic changes in response to acute exercise in more than 130 participants.This study employed a targeted quantitative approach using isotopically labeled internal standards to measure over 100 metabolites with DBS,providing accurate and traceable results.An accuracy assessment using standard reference material and stability testing over 90 days further evaluated the suitability of DBS for sports metabolomics.Results:Our findings confirm that DBS offers a valid approach to capture metabolic changes during exercise,with 11 compounds within the confidence interval of the reference material and 59 compounds overlapping with database values.A wide panel of metabolites showed significant changes in differences of absolute concentrations upon bout exercise,with succinate and xanthine being the most significant compounds.Metabolites from the underexplored class of pyrimidines also showed significant changes.Conclusion:While metabolic regulations upon exercise are similar in both sexes,differences in the correlation with fitness-related metadata,such as peak volitional oxygen consumption and performance,indicate a higher complexity in women and a limitation of previous knowledge to men only.The quantification approach together with the simplicity of the sampling paves the way to expand this type of research toward other fields of personalized medical services.展开更多
基金supported by grants from the Shanghai Science and Technology Commission(NO.13490503600)National Natural Science Foundation of China (NO.31171004)
文摘Growing literature has demonstrated that exercise may be an effective prevention and treatment option for drug addiction. In the past few years, many studies have suggested that there were sex differences in all phases of drug addiction. However, very limited research has investigated sex differences in the effectiveness of exercise intervention in drug addiction and rehabilitation. In this mini review, we summarize the effect of sex on the results of using exercise to prevent and treat drug addiction. The studies we consider span various animal models and use multiple types of exercise to examine the effectiveness of exercise on the neurobiological mechanism of exercise rehabilitation. We believe that exercise as an adjuvant intervention strategy can be applied better in drug addiction prevention and recovery. Copyright 2014, Shanghai University of Sport. Production and hosting by Elsevier B.V. All rights reserved.
文摘Objective To observe the efficacy of combining therapy in treatment of 90 patients with scapulohumeral periarthritis in different phases. Method Ninety patients with scapulohumeral periarthritis were treated with Fu＇s subcutaneous needling（FSN） combined with physiotherapy in painful phase, acupotomology and massage in adhesion phase, and appropriate functional exercise in rehabilitation phase. Seven days were considered as one course of treatment, and efficacy evaluation was performed after three courses. Function evaluation of shoulder joint was made. Result The total effective rate was 100%（38/38） in acute phase, 93.5%（29/31） in adhesion phase, and 100%（21/21） in rehabilitation phase. After treatment, the range of motion（ROM） of shoulder joint, pain, muscle force, activities of daily living（ADL） and joint local morphology of the patient have been improved obviously. Conclusion Better clinical efficacy is achieved in treatment of scapulohumeral periarthritis in different phases by combining therapy centering on FSN.
基金supported by grants from the Research Project of PLA(BLJ18J007)the National Natural Science Foundation of China(81730054)the Ministry of Health of China(201002012)。
文摘Background:Acute mountain sickness(AMS)is the mildest form of acute altitude illnesses,and consists of nonspecific symptoms when unacclimatized persons ascend to elevation of≥2500 m.Risk factors of AMS include:the altitude,individual susceptibility,ascending rate and degree of pre-acclimatization.In the current study,we examined whether physiological response at low altitude could predict the development of AMS.Methods:A total of 111 healthy adult healthy volunteers participated in this trial;and 99(67 men and 32 women)completed the entire study protocol.Subjects were asked to complete a 9-min exercise program using a mechanically braked bicycle ergometer at low altitude(500 m).Heart rate,blood pressure(BP)and pulse oxygen saturation(SpO2)were recorded prior to and during the last minute of exercise.The ascent from 500 m to 4100 m was completed in 2 days.AMS was defined as≥3 points in a 4-item Lake Louise Score,with at least one point from headache wat 6–8 h after the ascent.Results:Among the 99 assessable subjects,47(23 men and 24 women)developed AMS at 4100 m.In comparison to the subjects without AMS,those who developed AMS had lower proportion of men(48.9%vs.84.6%,P<0.001),height(168.4±5.9 cm vs.171.3±6.1 cm,P=0.019),weight(62.0±10.0 kg vs.66.7±8.6 kg,P=0.014)and proportion of smokers(23.4%vs.51.9%,P=0.004).Multivariate regression analysis revealed the following independent risks for AMS:female sex(odds ratio(OR)=6.32,P<0.001),SpO2 change upon exercise at low altitude(OR=0.63,P=0.002)and systolic BP change after the ascent(OR=0.96,P=0.029).Women had larger reduction in SpO2 after the ascent,higher AMS percentage and absolute AMS score.Larger reduction of SpO2 after exercise was associated with both AMS incidence(P=0.001)and AMS score(P<0.001)in men but not in women.Conclusions:Larger SpO2 reduction after exercise at low altitude was an independent risk for AMS upon ascent.Such an association was more robust in men than in women.Trial registration:Chinese Clinical Trial Registration,ChiCTR1900025728.Registered 6 September 2019.
基金Supported by Zhaoqing Philosophy and Social Sciences Planning Office Project(19ZC-19)Research and Practice Project of Promoting the High-quality Development of Basic Education by the Construction of New Normal School in 2023Key Research Platforms and Project Proposals for Ordinary Universities in 2022(2022ZDZX4058).
文摘As mental health issues among adolescents receive increasing attention,the impact of physical exercise on mental health has become prominent.In this paper,junior high school students in Luoding County and Yunan County of Yunfu are taken as participants.It employs a convenient sampling method to distribute questionnaires,utilizes relevant scales for measurement,and analyzes the data with the assistance of SPSS 26.0.The results indicate a significantly negative correlation between physical exercise and social anxiety.Overall,junior high school students in this region engage in relatively weak physical exercise,and their social anxiety is at a moderate level,with female students being more prone to anxiety.Left-behind children exhibit higher levels of social anxiety compared to non-left-behind children.There are notable differences among group characteristics,with social and cultural factors and physiological factors influencing gender differences,and the lack of family support affecting the social anxiety of left-behind children.This study provides a basis for intervening in psychological anxiety and other issues.It is suggested deepening the sports collaborative education mechanism,paying attention to the cultivation of social and emotional abilities of left-behind children,and using physical exercise to promote the development of students social adaptability.
文摘Purpose: Obtaining high peak bone mass (PBM) and maintaining bone mass is important for the prevention of osteoporosis. This study aimed to examine the regional differences in bone mineral density and factors associated with its acquisition from exercise. Design: The study population included 75 women of 18 - 22 years of age in East Japan and 104 women of 18 - 27 years of age in West Japan. The speed of sound (SOS) of the calcaneus was measured, and the young adult mean (%YAM) was calculated from the SOS. The subjects’ medical history, family history of osteoporosis, and exercise habits were examined using a self-administered questionnaire. Results: There were a significantly greater number of subjects with low %YAM in West Japan. The exercise history and exercise time were significantly higher in West Japan, and the exercise intensity score tended to be higher in East Japan during junior high and high school. A multiple regression analysis by region revealed that the following factors had a significant positive association with the SOS: exercise intensity at elementary school and outdoor sports at junior high school in East Japan;and exercise time at elementary school, muscle mass, and outdoor sports at junior high school in West Japan. On the other hand, exercise time in junior high school in West Japan showed a negative association with the SOS. Conclusions: Regional differences in bone mineral density existed, suggesting a trend toward lower bone mineral density in West Japan. Exercise history and time tended to be higher in West Japan, and exercise intensity scores tended to be higher in East Japan, suggesting that exercise intensity may be more important than exercise time for obtaining bone mineral density.
基金This work is supported by the University of Vienna,the Faculty of Chemistry and Centre for Sport Science and University Sports.The Vienna Business Agency,Austria funded FR.
文摘Background:Integrating metabolomics in sports science provides valuable insights into the biochemistry of bodies during physical activity.However,due to their invasiveness,traditional blood sampling methods present challenges in sports settings.The study investigated sex-specific metabolic responses,addressing a significant gap in exercise research,where female participation remains underrepresented.Methods:To address this,we explored volumetrically accurate microsampling as a dried blood spot(DBS)technique for assessing metabolomic changes in response to acute exercise in more than 130 participants.This study employed a targeted quantitative approach using isotopically labeled internal standards to measure over 100 metabolites with DBS,providing accurate and traceable results.An accuracy assessment using standard reference material and stability testing over 90 days further evaluated the suitability of DBS for sports metabolomics.Results:Our findings confirm that DBS offers a valid approach to capture metabolic changes during exercise,with 11 compounds within the confidence interval of the reference material and 59 compounds overlapping with database values.A wide panel of metabolites showed significant changes in differences of absolute concentrations upon bout exercise,with succinate and xanthine being the most significant compounds.Metabolites from the underexplored class of pyrimidines also showed significant changes.Conclusion:While metabolic regulations upon exercise are similar in both sexes,differences in the correlation with fitness-related metadata,such as peak volitional oxygen consumption and performance,indicate a higher complexity in women and a limitation of previous knowledge to men only.The quantification approach together with the simplicity of the sampling paves the way to expand this type of research toward other fields of personalized medical services.
