An in situ coupling strategy to prepare Co_9S_8/S and N dual?doped graphene composite(Co_9S_8/NSG) has been proposed. The key point of this strategy is the function?oriented design of organic compounds. Herein, cobalt...An in situ coupling strategy to prepare Co_9S_8/S and N dual?doped graphene composite(Co_9S_8/NSG) has been proposed. The key point of this strategy is the function?oriented design of organic compounds. Herein, cobalt porphyrin derivatives with sulfo groups are employed as not only the coupling agents to form and anchor Co_9S_8 on the graphene in situ, but also the heteroatom?doped agent to generate S and N dual?doped graphene. The tight coupling of multiple active sites endows the composite materials with fast electrochemical kinetics and excellent stability for both oxygen reduction reaction(ORR) and oxygen evolution reaction(OER). The obtained electrocatalyst exhibits better activity parameter(ΔE = 0.82 V) and smaller Tafel slope(47.7 mV dec^(-1) for ORR and 69.2 mV dec^(-1) for OER) than commercially available Pt/C and RuO_2. Most importantly, as electrocatalyst for rechargeable Zn–air battery, Co_9S_8/NSG displays low charge–discharge voltage gap and outstanding long?term cycle stability over 138 h compared to Pt/C–RuO_2. To further broaden its application scope, a homemade all?solid?state Zn–air battery is also prepared, which displays good charge–discharge performance and cycle performance. The function?oriented design of N_4?metallomacrocycle derivatives might open new avenues to strategic construction of high?performance and long?life multifunctional electrocatalysts for wider electro?chemical energy applications.展开更多
In the process of grid-connected wind and solar power generation,there are problems of high rate of abandoning wind and light and insufficient energy.In order to solve these problems,we construct a grid-connected wind...In the process of grid-connected wind and solar power generation,there are problems of high rate of abandoning wind and light and insufficient energy.In order to solve these problems,we construct a grid-connected wind-solar hydrogen storage(alkaline electrolyzer(AE)-hydrogen storage tank-battery-proton exchange membrane fuel cell(PEMFC))coupled system architecture.A grid-connected compensation/consumption hierarchical control strategy based on wind-solar hydrogen coupling is proposed.During the grid-connected process of wind and solar power generation,the upper-level control allocates power reasonably to the hydrogen energy storage system by dispatching the power of wind and solar power generation.At the same time,the control strategy ensures that the pressure of the hydrogen storage tank is within the safety range limit,and the lower control completes the control of the duty cycle of the converter in the system.Due to the randomness of wind and light,the hydrogen energy storage system is divided into three working conditions,namely compensation,balance and consumption,and five working modes.The simulation results show that the hydrogen energy storage system compensates for 40%of the power shortage,and consumes 27.5%of the abandoned wind and solar energy,which improves the utilization rate of clean energy.展开更多
Coupling adsorption and in-situ Fenton-like oxidation process was developed for Methylene blue(MB) using refined iron-containing lowgrade attapulgite(ATP) clay, and the removal mechanism was investigated. The MB was i...Coupling adsorption and in-situ Fenton-like oxidation process was developed for Methylene blue(MB) using refined iron-containing lowgrade attapulgite(ATP) clay, and the removal mechanism was investigated. The MB was initially adsorbed on the porous ATPs, and then the enriched MB was removed by the H2O2-assisted Fenton-like oxidation with the iron-containing ATP catalyst. Under optimal conditions, the ATP powder exhibits the maximum removal efficiency of 100% with negligible iron leaching(1.5 mg L^(-1)) and no sludge formation. Furthermore,polysulfone/ATP(PSF/ATP) pellets were fabricated through a water-induced phase separation process to construct a fixed-bed reactor(FBR) for continuous contaminant removal. For the first cycle, the maximum adsorption capacity was 15.5 L with an outlet MB concentration of1.973 mg L-1(< 2 mg L^(-1), GB4287-2012) using the PSF/ATP pellets containing 50.0 g of ATP powders, and the maximum Fenton-like oxidation capacity was 35.5 L with the outlet concentration of 0.831 mg L^(-1). After five cycles, the total treated volume of the MB solution was ca. 255 L, and the efficiency remained above 99%. After 10 h of continuous treatment towards practical resin industrial wastewater, the chemical oxygen demand(COD) removal efficiency was still measured at 83.05%, costing 0.398 $ m^(-3). These results demonstrate the practical applicability of iron-containing low-grade ATP clay for textile water treatment.展开更多
A new control strategy named adjacent coupling error strategy is proposed to multi-motor drive system. The adjacent coupling error control scheme is developed considering the tracking speed error in one motor and the ...A new control strategy named adjacent coupling error strategy is proposed to multi-motor drive system. The adjacent coupling error control scheme is developed considering the tracking speed error in one motor and the synchronous error among adjacent motors simultaneously. In the strategy, due to non-linear effects of the two mentioned errors to the motion control of motor i, an adaptive fuzzy logic controller is designed to decide the control variable of the motor drive system. The multi-motor drive system is modeled and simulated by SIMULINK. The simulated researches show that the proposed strategy improves the synchronization, stabilization, and convergence of the multi-motor system.展开更多
Based on analyzing the structure and working principle on electric vehicles （EVs） with dual motors coupled by planetarY gears, the control strategy of mode switching was proposed. The power interruption problem on E...Based on analyzing the structure and working principle on electric vehicles （EVs） with dual motors coupled by planetarY gears, the control strategy of mode switching was proposed. The power interruption problem on EVs with automatic mechanical transmission （AMT） shifting was resolved. Based on the speed-torque characteristics of the planetary gears and the principle of the auxiliary motor＇ s zero speed braking, control features of mode switching were introduced. The mode shifting between the main motor mode and dual motors coupled driving were studied. Matlab/Simulink was adopted as a platform to develop the simulation model of EVs with dual motors drive system and 3 gears AMT. Simulation results demonstrated that the power interruption of dual motors drive system was solved during mode switching. The power requirements of EVs were satisfied, too.展开更多
The present study aimed to clarify the smoking cessation motivations, challenges and coping strategies among pregnant couples. A qualitative design using a grounded theory approach was applied. Data were collected by ...The present study aimed to clarify the smoking cessation motivations, challenges and coping strategies among pregnant couples. A qualitative design using a grounded theory approach was applied. Data were collected by individual semi-structured interviews with 39 married individuals(21 non-smoking pregnant women and 18 smoking or ever-smoking men with a pregnant wife) and 3 imams in an ethnically diverse region of far western China. The most common theme for smoking cessation motivation was 'embryo quality'(i.e., a healthier baby), followed by family's health. Most interviewees reported that husband's withdrawal symptoms were the greatest challenge to smoking cessation, followed by the Chinese tobacco culture. Coping strategies given by the pregnant women typically involved combining emotional, behavioral and social interventions. Social interventions showed advantages in helping to quit smoking. Pregnancy appears to be a positive stimulus for pregnant couples' smoking cessation. Our results suggest that pregnancy, a highly important life event, may help to reduce barriers to smoking cessation at the social level(e.g., limiting access to cigarettes, avoiding temptation to smoke), but does little to help with the withdrawal symptoms. Professional guidance for smoking cessation is still necessary.展开更多
This paper addresses the micro wind-hydrogen coupled system,aiming to improve the power tracking capability of micro wind farms,the regulation capability of hydrogen storage systems,and to mitigate the volatility of w...This paper addresses the micro wind-hydrogen coupled system,aiming to improve the power tracking capability of micro wind farms,the regulation capability of hydrogen storage systems,and to mitigate the volatility of wind power generation.A predictive control strategy for the micro wind-hydrogen coupled system is proposed based on the ultra-short-term wind power prediction,the hydrogen storage state division interval,and the daily scheduled output of wind power generation.The control strategy maximizes the power tracking capability,the regulation capability of the hydrogen storage system,and the fluctuation of the joint output of the wind-hydrogen coupled system as the objective functions,and adaptively optimizes the control coefficients of the hydrogen storage interval and the output parameters of the system by the combined sigmoid function and particle swarm algorithm(sigmoid-PSO).Compared with the real-time control strategy,the proposed predictive control strategy can significantly improve the output tracking capability of the wind-hydrogen coupling system,minimize the gap between the actual output and the predicted output,significantly enhance the regulation capability of the hydrogen storage system,and mitigate the power output fluctuation of the wind-hydrogen integrated system,which has a broad practical application prospect.展开更多
Coupled turbulent flow, temperature fields of the twin-roll casting strip process were simulated by three-dimensional finite element method. Based on the heat balance calculation and using inverse methods between the ...Coupled turbulent flow, temperature fields of the twin-roll casting strip process were simulated by three-dimensional finite element method. Based on the heat balance calculation and using inverse methods between the simulations and real experiments, the relational models among casting speed, location, and coefficient of heat transfer between molten metal and rolls in different regions are given. In the simulation, the calculated surface temperatures are in good agreement with the measured values. An on-line model of kiss point is derived by simulations and the geometry of molten pool, corresponding control strategy is also proposed.展开更多
In order to improve the frequency response and anti-interference characteristics of the smart electromechanical actuator(EMA)system,and aiming at the force fighting problem when multiple actuators work synchronously,a...In order to improve the frequency response and anti-interference characteristics of the smart electromechanical actuator(EMA)system,and aiming at the force fighting problem when multiple actuators work synchronously,a multi input multi output(MIMO)position difference cross coupling control coordinated strategy based on double‑closed-loop load feedforward control is proposed and designed.In this strategy,the singular value method of return difference matrix is used to design the parameter range that meets the requirements of system stability margin,and the sensitivity function and the H_(∞)norm theory are used to design and determine the optimal solution in the obtained parameter stability region,so that the multi actuator system has excellent synchronization,stability and anti-interference.At the same time,the mathematical model of the integrated smart EMA system is established.According to the requirements of point-to-point control,the controller of double-loop control and load feedforward compensation is determined and designed to improve the frequency response and anti-interference ability of single actuator.Finally,the 270 V high-voltage smart EMA system experimental platform is built,and the frequency response,load feedforward compensation and coordinated control experiments are carried out to verify the correctness of the position difference cross coupling control strategy and the rationality of the parameter design,so that the system can reach the servo control indexes of bandwidth 6 Hz,the maximum output force 20000 N and the synchronization error≤0.1 mm,which effectively solves the problem of force fighting.展开更多
(R)-2-Hydroxy-4-phenylbutyric acid ethyl ester((R)-HPBE)is an essential chiral intermediate in the synthesis of angiotensin-converting enzyme(ACE)inhibitors.Its production involves the highly selective asymmetric redu...(R)-2-Hydroxy-4-phenylbutyric acid ethyl ester((R)-HPBE)is an essential chiral intermediate in the synthesis of angiotensin-converting enzyme(ACE)inhibitors.Its production involves the highly selective asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate(OPBE),catalyzed by carbonyl reductase(CpCR),with efficient cofactor regeneration playing a crucial role.In this study,an in-situ coenzyme regeneration system was developed by coupling carbonyl reductase(CpCR)with glucose dehydrogenase(GDH),resulting in the construction of five recombinant strains capable of NADPH regeneration.Among these,the recombinant strain E.coli BL21-pETDuet-1-GDH-L-CpCR,where CpCR is fused to the C-terminus of GDH,demonstrated the highest catalytic activity.This strain exhibited an enzyme activity of 69.78 U/mg and achieved a conversion rate of 98.3%,with an enantiomeric excess(ee)of 99.9%during the conversion of 30 mM OPBE to(R)-HPBE.High-density fermentation further enhanced enzyme yield,achieving an enzyme activity of 1960 U/mL in the fermentation broth,which is 16.2 times higher than the volumetric activity obtained from shake flask fermentation.Additionally,the implementation of a substrate feeding strategy enabled continuous processing,allowing the strain to efficiently convert a final OPBE concentration of 920 mM,producing 912 mM of(R)-HPBE.These findings highlight the system’s improved catalytic efficiency,stability,and scalability,making it highly suitable for industrial-scale biocatalytic production.展开更多
Over the last 20 years, silicon photonics has revolutionized the field of integrated optics, providing a novel and powerful platform to build mass-producible optical circuits. One of the most attractive aspects of sil...Over the last 20 years, silicon photonics has revolutionized the field of integrated optics, providing a novel and powerful platform to build mass-producible optical circuits. One of the most attractive aspects of silicon photonics is its ability to provide extremely small optical components, whose typical dimensions are an order of magnitude smaller than those of optical fiber devices. This dimension difference makes the design of fiberto-chip interfaces challenging and, over the years, has stimulated considerable technical and research efforts in the field. Fiber-to-silicon photonic chip interfaces can be broadly divided into two principle categories:in-plane and out-of-plane couplers. Devices falling into the first category typically offer relatively high coupling efficiency, broad coupling bandwidth(in wavelength), and low polarization dependence but require relatively complex fabrication and assembly procedures that are not directly compatible with wafer-scale testing.Conversely, out-of-plane coupling devices offer lower efficiency, narrower bandwidth, and are usually polarization dependent. However, they are often more compatible with high-volume fabrication and packaging processes and allow for on-wafer access to any part of the optical circuit. In this paper, we review the current state-of-the-art of optical couplers for photonic integrated circuits, aiming to give to the reader a comprehensive and broad view of the field, identifying advantages and disadvantages of each solution. As fiber-to-chip couplers are inherently related to packaging technologies and the co-design of optical packages has become essential, we also review the main solutions currently used to package and assemble optical fibers with silicon-photonic integrated circuits.展开更多
基金supported by the National Natural Science Foundation of China (Grant No. 21404014)the Science & Technology Department of Jilin Province (No. 20170101177JC)
文摘An in situ coupling strategy to prepare Co_9S_8/S and N dual?doped graphene composite(Co_9S_8/NSG) has been proposed. The key point of this strategy is the function?oriented design of organic compounds. Herein, cobalt porphyrin derivatives with sulfo groups are employed as not only the coupling agents to form and anchor Co_9S_8 on the graphene in situ, but also the heteroatom?doped agent to generate S and N dual?doped graphene. The tight coupling of multiple active sites endows the composite materials with fast electrochemical kinetics and excellent stability for both oxygen reduction reaction(ORR) and oxygen evolution reaction(OER). The obtained electrocatalyst exhibits better activity parameter(ΔE = 0.82 V) and smaller Tafel slope(47.7 mV dec^(-1) for ORR and 69.2 mV dec^(-1) for OER) than commercially available Pt/C and RuO_2. Most importantly, as electrocatalyst for rechargeable Zn–air battery, Co_9S_8/NSG displays low charge–discharge voltage gap and outstanding long?term cycle stability over 138 h compared to Pt/C–RuO_2. To further broaden its application scope, a homemade all?solid?state Zn–air battery is also prepared, which displays good charge–discharge performance and cycle performance. The function?oriented design of N_4?metallomacrocycle derivatives might open new avenues to strategic construction of high?performance and long?life multifunctional electrocatalysts for wider electro?chemical energy applications.
基金Xi’an Key Laboratory of Clean Energy(No.2019219914SYS014CG036)Natural Science Foundation of Xi’an City(No.XA2020-CXRCFW-0247)Yulin Industry-University-Research Cooperation Project(No.2019-173)。
文摘In the process of grid-connected wind and solar power generation,there are problems of high rate of abandoning wind and light and insufficient energy.In order to solve these problems,we construct a grid-connected wind-solar hydrogen storage(alkaline electrolyzer(AE)-hydrogen storage tank-battery-proton exchange membrane fuel cell(PEMFC))coupled system architecture.A grid-connected compensation/consumption hierarchical control strategy based on wind-solar hydrogen coupling is proposed.During the grid-connected process of wind and solar power generation,the upper-level control allocates power reasonably to the hydrogen energy storage system by dispatching the power of wind and solar power generation.At the same time,the control strategy ensures that the pressure of the hydrogen storage tank is within the safety range limit,and the lower control completes the control of the duty cycle of the converter in the system.Due to the randomness of wind and light,the hydrogen energy storage system is divided into three working conditions,namely compensation,balance and consumption,and five working modes.The simulation results show that the hydrogen energy storage system compensates for 40%of the power shortage,and consumes 27.5%of the abandoned wind and solar energy,which improves the utilization rate of clean energy.
基金supported by Gansu Cuihua Technology Co.,Ltd.(H2020292)Science and Technology Planning of Baiyin City,Fundamental Research Funds for the Central Universities (buctrc202208)+2 种基金Engineering Research Center of Non-metallic Minerals of Zhejiang Province and the Beijing Engineering Center for Hierarchical Catalysts. Central Government Guiding Funds for Local Science and Technology Development (2022ZY015)Nanjiang Technology Project(2023AB028)Open Laboratory of State Key Laboratory of Organic and Inorganic Composites (oic-202301006)。
文摘Coupling adsorption and in-situ Fenton-like oxidation process was developed for Methylene blue(MB) using refined iron-containing lowgrade attapulgite(ATP) clay, and the removal mechanism was investigated. The MB was initially adsorbed on the porous ATPs, and then the enriched MB was removed by the H2O2-assisted Fenton-like oxidation with the iron-containing ATP catalyst. Under optimal conditions, the ATP powder exhibits the maximum removal efficiency of 100% with negligible iron leaching(1.5 mg L^(-1)) and no sludge formation. Furthermore,polysulfone/ATP(PSF/ATP) pellets were fabricated through a water-induced phase separation process to construct a fixed-bed reactor(FBR) for continuous contaminant removal. For the first cycle, the maximum adsorption capacity was 15.5 L with an outlet MB concentration of1.973 mg L-1(< 2 mg L^(-1), GB4287-2012) using the PSF/ATP pellets containing 50.0 g of ATP powders, and the maximum Fenton-like oxidation capacity was 35.5 L with the outlet concentration of 0.831 mg L^(-1). After five cycles, the total treated volume of the MB solution was ca. 255 L, and the efficiency remained above 99%. After 10 h of continuous treatment towards practical resin industrial wastewater, the chemical oxygen demand(COD) removal efficiency was still measured at 83.05%, costing 0.398 $ m^(-3). These results demonstrate the practical applicability of iron-containing low-grade ATP clay for textile water treatment.
基金National Natural Science Foundation of China (No.60774023)
文摘A new control strategy named adjacent coupling error strategy is proposed to multi-motor drive system. The adjacent coupling error control scheme is developed considering the tracking speed error in one motor and the synchronous error among adjacent motors simultaneously. In the strategy, due to non-linear effects of the two mentioned errors to the motion control of motor i, an adaptive fuzzy logic controller is designed to decide the control variable of the motor drive system. The multi-motor drive system is modeled and simulated by SIMULINK. The simulated researches show that the proposed strategy improves the synchronization, stabilization, and convergence of the multi-motor system.
基金Supported by Doctoral Fund of Ministry of Education of China(20101101110012)the National Natural Science Foundationof China(51175040)
文摘Based on analyzing the structure and working principle on electric vehicles （EVs） with dual motors coupled by planetarY gears, the control strategy of mode switching was proposed. The power interruption problem on EVs with automatic mechanical transmission （AMT） shifting was resolved. Based on the speed-torque characteristics of the planetary gears and the principle of the auxiliary motor＇ s zero speed braking, control features of mode switching were introduced. The mode shifting between the main motor mode and dual motors coupled driving were studied. Matlab/Simulink was adopted as a platform to develop the simulation model of EVs with dual motors drive system and 3 gears AMT. Simulation results demonstrated that the power interruption of dual motors drive system was solved during mode switching. The power requirements of EVs were satisfied, too.
基金supported by the National Philosophy and Social Science Foundation of China(No.15ZDC037)the National Natural Science Foundation of China(key program)(No.71333005)
文摘The present study aimed to clarify the smoking cessation motivations, challenges and coping strategies among pregnant couples. A qualitative design using a grounded theory approach was applied. Data were collected by individual semi-structured interviews with 39 married individuals(21 non-smoking pregnant women and 18 smoking or ever-smoking men with a pregnant wife) and 3 imams in an ethnically diverse region of far western China. The most common theme for smoking cessation motivation was 'embryo quality'(i.e., a healthier baby), followed by family's health. Most interviewees reported that husband's withdrawal symptoms were the greatest challenge to smoking cessation, followed by the Chinese tobacco culture. Coping strategies given by the pregnant women typically involved combining emotional, behavioral and social interventions. Social interventions showed advantages in helping to quit smoking. Pregnancy appears to be a positive stimulus for pregnant couples' smoking cessation. Our results suggest that pregnancy, a highly important life event, may help to reduce barriers to smoking cessation at the social level(e.g., limiting access to cigarettes, avoiding temptation to smoke), but does little to help with the withdrawal symptoms. Professional guidance for smoking cessation is still necessary.
基金the Key Research&Development Program of Xinjiang(Grant Number 2022B01003).
文摘This paper addresses the micro wind-hydrogen coupled system,aiming to improve the power tracking capability of micro wind farms,the regulation capability of hydrogen storage systems,and to mitigate the volatility of wind power generation.A predictive control strategy for the micro wind-hydrogen coupled system is proposed based on the ultra-short-term wind power prediction,the hydrogen storage state division interval,and the daily scheduled output of wind power generation.The control strategy maximizes the power tracking capability,the regulation capability of the hydrogen storage system,and the fluctuation of the joint output of the wind-hydrogen coupled system as the objective functions,and adaptively optimizes the control coefficients of the hydrogen storage interval and the output parameters of the system by the combined sigmoid function and particle swarm algorithm(sigmoid-PSO).Compared with the real-time control strategy,the proposed predictive control strategy can significantly improve the output tracking capability of the wind-hydrogen coupling system,minimize the gap between the actual output and the predicted output,significantly enhance the regulation capability of the hydrogen storage system,and mitigate the power output fluctuation of the wind-hydrogen integrated system,which has a broad practical application prospect.
基金supported by National Key Research Development Planning Project of China (2004CB619108).
文摘Coupled turbulent flow, temperature fields of the twin-roll casting strip process were simulated by three-dimensional finite element method. Based on the heat balance calculation and using inverse methods between the simulations and real experiments, the relational models among casting speed, location, and coefficient of heat transfer between molten metal and rolls in different regions are given. In the simulation, the calculated surface temperatures are in good agreement with the measured values. An on-line model of kiss point is derived by simulations and the geometry of molten pool, corresponding control strategy is also proposed.
基金supported by the National Natural Science Foundation of China(No.52077100)the Aviation Science Foundation(No.201958052001)
文摘In order to improve the frequency response and anti-interference characteristics of the smart electromechanical actuator(EMA)system,and aiming at the force fighting problem when multiple actuators work synchronously,a multi input multi output(MIMO)position difference cross coupling control coordinated strategy based on double‑closed-loop load feedforward control is proposed and designed.In this strategy,the singular value method of return difference matrix is used to design the parameter range that meets the requirements of system stability margin,and the sensitivity function and the H_(∞)norm theory are used to design and determine the optimal solution in the obtained parameter stability region,so that the multi actuator system has excellent synchronization,stability and anti-interference.At the same time,the mathematical model of the integrated smart EMA system is established.According to the requirements of point-to-point control,the controller of double-loop control and load feedforward compensation is determined and designed to improve the frequency response and anti-interference ability of single actuator.Finally,the 270 V high-voltage smart EMA system experimental platform is built,and the frequency response,load feedforward compensation and coordinated control experiments are carried out to verify the correctness of the position difference cross coupling control strategy and the rationality of the parameter design,so that the system can reach the servo control indexes of bandwidth 6 Hz,the maximum output force 20000 N and the synchronization error≤0.1 mm,which effectively solves the problem of force fighting.
基金supported by the Zhejiang Provincial Science and Technology Plan Project(2024C03014)the National Nature Science Foundation of China(Project Nos.21978267,and 22078300)as well as the Natural Science Foundation of Heilongjiang Province(LH2022H107).
文摘(R)-2-Hydroxy-4-phenylbutyric acid ethyl ester((R)-HPBE)is an essential chiral intermediate in the synthesis of angiotensin-converting enzyme(ACE)inhibitors.Its production involves the highly selective asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate(OPBE),catalyzed by carbonyl reductase(CpCR),with efficient cofactor regeneration playing a crucial role.In this study,an in-situ coenzyme regeneration system was developed by coupling carbonyl reductase(CpCR)with glucose dehydrogenase(GDH),resulting in the construction of five recombinant strains capable of NADPH regeneration.Among these,the recombinant strain E.coli BL21-pETDuet-1-GDH-L-CpCR,where CpCR is fused to the C-terminus of GDH,demonstrated the highest catalytic activity.This strain exhibited an enzyme activity of 69.78 U/mg and achieved a conversion rate of 98.3%,with an enantiomeric excess(ee)of 99.9%during the conversion of 30 mM OPBE to(R)-HPBE.High-density fermentation further enhanced enzyme yield,achieving an enzyme activity of 1960 U/mL in the fermentation broth,which is 16.2 times higher than the volumetric activity obtained from shake flask fermentation.Additionally,the implementation of a substrate feeding strategy enabled continuous processing,allowing the strain to efficiently convert a final OPBE concentration of 920 mM,producing 912 mM of(R)-HPBE.These findings highlight the system’s improved catalytic efficiency,stability,and scalability,making it highly suitable for industrial-scale biocatalytic production.
基金Engineering and Physical Sciences Research Council(EPSRC)(EP/L00044X/1)
文摘Over the last 20 years, silicon photonics has revolutionized the field of integrated optics, providing a novel and powerful platform to build mass-producible optical circuits. One of the most attractive aspects of silicon photonics is its ability to provide extremely small optical components, whose typical dimensions are an order of magnitude smaller than those of optical fiber devices. This dimension difference makes the design of fiberto-chip interfaces challenging and, over the years, has stimulated considerable technical and research efforts in the field. Fiber-to-silicon photonic chip interfaces can be broadly divided into two principle categories:in-plane and out-of-plane couplers. Devices falling into the first category typically offer relatively high coupling efficiency, broad coupling bandwidth(in wavelength), and low polarization dependence but require relatively complex fabrication and assembly procedures that are not directly compatible with wafer-scale testing.Conversely, out-of-plane coupling devices offer lower efficiency, narrower bandwidth, and are usually polarization dependent. However, they are often more compatible with high-volume fabrication and packaging processes and allow for on-wafer access to any part of the optical circuit. In this paper, we review the current state-of-the-art of optical couplers for photonic integrated circuits, aiming to give to the reader a comprehensive and broad view of the field, identifying advantages and disadvantages of each solution. As fiber-to-chip couplers are inherently related to packaging technologies and the co-design of optical packages has become essential, we also review the main solutions currently used to package and assemble optical fibers with silicon-photonic integrated circuits.
