Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications i...Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.展开更多
In this paper,the research status of industrial ecology abroad is briefly introduced,and the development status of industrial ecology in China is summarized and evaluated,including research content,methods,application...In this paper,the research status of industrial ecology abroad is briefly introduced,and the development status of industrial ecology in China is summarized and evaluated,including research content,methods,applications,etc.At the same time,combined with the current needs of China s economic-social development,it looks forward to the future development direction and application prospects of industrial ecology.In the coming period,research on green transformation technologies for industrial structure and production methods,carbon peak routes and carbon reduction implementation paths for industrial systems,key technologies for adapting to climate change and achieving carbon peak and carbon neutrality in priority areas,cross regional collaborative technologies for industrial chains,regional energy resource optimization and allocation technologies,efficient industrial agglomeration and collaboration technologies,multimedia composite pollution collaborative governance technologies,collaborative governance technologies for pollution and carbon reduction,multimedia comprehensive governance of multiple pollutants,and empirical theoretical systems of industrial ecology with Chinese characteristics will be the direction of industrial ecology research in China.展开更多
In the area of reservoir engineering,the optimization of oil and gas production is a complex task involving a myriad of interconnected decision variables shaping the production system's infrastructure.Traditionall...In the area of reservoir engineering,the optimization of oil and gas production is a complex task involving a myriad of interconnected decision variables shaping the production system's infrastructure.Traditionally,this optimization process was centered on a single objective,such as net present value,return on investment,cumulative oil production,or cumulative water production.However,the inherent complexity of reservoir exploration necessitates a departure from this single-objective approach.Mul-tiple conflicting production and economic indicators must now be considered to enable more precise and robust decision-making.In response to this challenge,researchers have embarked on a journey to explore field development optimization of multiple conflicting criteria,employing the formidable tools of multi-objective optimization algorithms.These algorithms delve into the intricate terrain of production strategy design,seeking to strike a delicate balance between the often-contrasting objectives.Over the years,a plethora of these algorithms have emerged,ranging from a priori methods to a posteriori approach,each offering unique insights and capabilities.This survey endeavors to encapsulate,catego-rize,and scrutinize these invaluable contributions to field development optimization,which grapple with the complexities of multiple conflicting objective functions.Beyond the overview of existing methodologies,we delve into the persisting challenges faced by researchers and practitioners alike.Notably,the application of multi-objective optimization techniques to production optimization is hin-dered by the resource-intensive nature of reservoir simulation,especially when confronted with inherent uncertainties.As a result of this survey,emerging opportunities have been identified that will serve as catalysts for pivotal research endeavors in the future.As intelligent and more efficient algo-rithms continue to evolve,the potential for addressing hitherto insurmountable field development optimization obstacles becomes increasingly viable.This discussion on future prospects aims to inspire critical research,guiding the way toward innovative solutions in the ever-evolving landscape of oil and gas production optimization.展开更多
This paper investigates and analyzes the general situation of the tomato seed production industry in Lintong District,Xi'an City.Development strategies and suggestions are proposed to address existing problems.The...This paper investigates and analyzes the general situation of the tomato seed production industry in Lintong District,Xi'an City.Development strategies and suggestions are proposed to address existing problems.These include strengthening technological innovation and variety R&D,promoting industrial standardization and intelligent upgrading,enhancing brand building and market expansion,improving policy support and industrial chain coordination,strengthening intellectual property protection and talent cultivation,and expanding sales channels to promote industrial transformation and upgrading.展开更多
Background:In recent years,there has been a growing trend in the utilization of observational studies that make use of routinely collected healthcare data(RCD).These studies rely on algorithms to identify specific hea...Background:In recent years,there has been a growing trend in the utilization of observational studies that make use of routinely collected healthcare data(RCD).These studies rely on algorithms to identify specific health conditions(e.g.,diabetes or sepsis)for statistical analyses.However,there has been substantial variation in the algorithm development and validation,leading to frequently suboptimal performance and posing a significant threat to the validity of study findings.Unfortunately,these issues are often overlooked.Methods:We systematically developed guidance for the development,validation,and evaluation of algorithms designed to identify health status(DEVELOP-RCD).Our initial efforts involved conducting both a narrative review and a systematic review of published studies on the concepts and methodological issues related to algorithm development,validation,and evaluation.Subsequently,we conducted an empirical study on an algorithm for identifying sepsis.Based on these findings,we formulated specific workflow and recommendations for algorithm development,validation,and evaluation within the guidance.Finally,the guidance underwent independent review by a panel of 20 external experts who then convened a consensus meeting to finalize it.Results:A standardized workflow for algorithm development,validation,and evaluation was established.Guided by specific health status considerations,the workflow comprises four integrated steps:assessing an existing algorithm’s suitability for the target health status;developing a new algorithm using recommended methods;validating the algorithm using prescribed performance measures;and evaluating the impact of the algorithm on study results.Additionally,13 good practice recommendations were formulated with detailed explanations.Furthermore,a practical study on sepsis identification was included to demonstrate the application of this guidance.Conclusions:The establishment of guidance is intended to aid researchers and clinicians in the appropriate and accurate development and application of algorithms for identifying health status from RCD.This guidance has the potential to enhance the credibility of findings from observational studies involving RCD.展开更多
This paper focuses on Guizhou's health and wellness industry and rural revitalization,delving deeply into their foundational theories,historical evolution,current status,technological progress,future prospects,and...This paper focuses on Guizhou's health and wellness industry and rural revitalization,delving deeply into their foundational theories,historical evolution,current status,technological progress,future prospects,and points of contention.Through a comprehensive analysis of relevant references,it elaborates on the definition of the health and wellness industry and Guizhou's geographical advantages,reviews the background and implementation pathways of the rural revitalization strategy,and analyzes the mechanism for their synergistic development.It reviews the respective development trajectories of Guizhou's health and wellness industry and rural revitalization,as well as their integration process,analyzes the current status and market demand,the challenges faced,and the status of their integration.It explores the application of technological innovations,strategies for technology empowerment,and cases of technology integration,forecasts future development trends,plans,and paths for integrated development,and discusses contentious points such as benefit distribution,environmental protection,and policy coordination,aiming to provide comprehensive theoretical and practical references for the further development of Guizhou's health and wellness industry and rural revitalization.展开更多
This paper investigated and analyzed the conservation and utilization of four local livestock breeds in Binzhou City:Wadi Sheep,Bohai Black Cattle,Wudi Donkey,and Lubei White Goat.Shortcomings in the protection and ut...This paper investigated and analyzed the conservation and utilization of four local livestock breeds in Binzhou City:Wadi Sheep,Bohai Black Cattle,Wudi Donkey,and Lubei White Goat.Shortcomings in the protection and utilization of local germplasm resources were pointed out,and strategies and recommendations were proposed to promote high-quality development of livestock and poultry genetic resources in Binzhou,including building a solid germplasm foundation,standardizing production,and driving innovation.This paper provides references for the conservation,development,and utilization of local genetic resources in Binzhou City.展开更多
The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to ...The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to more than 30% of the world's population,predominantly in developing countries where per capita farmland and food supply are only 40% of those in developed nations(FAO 2018).Meeting the Zero Hunger target amid ongoing population growth in these regions requires a substantial increase in agricultural production while minimizing soil degradation and adverse ecological impacts.This challenge is shared by many countries across South Asia,Africa,and Central and South America.展开更多
Innovation and Development Policy,简称“IDP”,中文名:《创新与发展政策(英文)》,是由中国科学院主管,中国科学院科技战略咨询研究院、中国科学学与科技政策研究会共同主办,国内外发行(ISSN:2096-5141,CN:10-1513/D)的英文国际期刊...Innovation and Development Policy,简称“IDP”,中文名:《创新与发展政策(英文)》,是由中国科学院主管,中国科学院科技战略咨询研究院、中国科学学与科技政策研究会共同主办,国内外发行(ISSN:2096-5141,CN:10-1513/D)的英文国际期刊。目前期刊每年出版两期。已发表论文在期刊网站可以自由获取,http://idp-journal.casisd.cn/browse/al/al2019/。展开更多
Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.You...Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.Young students,with their active and vibrant minds,represent the future and hope of standardization.展开更多
China is carving out a distinctive development path which features urban-rural integration.This approach has not only yielded tangible results domestically but also drawn the attention of other countries.
Hepatocellular carcinoma presents with three distinct immune phenotypes,including immune-desert,immune-excluded,and immune-inflamed,indicating various treatment responses and prognostic outcomes.The clinical applicati...Hepatocellular carcinoma presents with three distinct immune phenotypes,including immune-desert,immune-excluded,and immune-inflamed,indicating various treatment responses and prognostic outcomes.The clinical application of multi-omics parameters is still restricted by the expensive and less accessible assays,although they accurately reflect immune status.A comprehensive evaluation framework based on“easy-to-obtain”multi-model clinical parameters is urgently required,incorporating clinical features to establish baseline patient profiles and disease staging;routine blood tests assessing systemic metabolic and functional status;immune cell subsets quantifying subcluster dynamics;imaging features delineating tumor morphology,spatial configuration,and perilesional anatomical relationships;immunohistochemical markers positioning qualitative and quantitative detection of tumor antigens from the cellular and molecular level.This integrated phenomic approach aims to improve prognostic stratification and clinical decision-making in hepatocellular carcinoma management conveniently and practically.展开更多
To advance intelligent construction,standards must come first.The Ministry of Housing and Urban-Rural Development has issued the List for Replicable Experience and Practices for Developing Intelligent Construction fou...To advance intelligent construction,standards must come first.The Ministry of Housing and Urban-Rural Development has issued the List for Replicable Experience and Practices for Developing Intelligent Construction four times successively and the Technical Guidelines for Intelligent Construction(Trial).展开更多
China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have alwa...China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have always been a priority in national development.At its fourth plenary session held in October 2025,the 20th Central Committee of the Communist Party of China(CPC)once again emphasized the need to accelerate agricultural and rural modernization,and advance all-around rural revitalization over the next five years.展开更多
Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables th...Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs.展开更多
Against the backdrop of China s accelerated green development and its pursuit of the"dual carbon"goals,green finance,as a crucial instrument for the rational allocation of resources,plays a significant role ...Against the backdrop of China s accelerated green development and its pursuit of the"dual carbon"goals,green finance,as a crucial instrument for the rational allocation of resources,plays a significant role in promoting agricultural green transformation.Taking Henan Province as a case study,this research employs panel data from 18 prefecture-level cities spanning 2014 to 2023,utilizing dynamic panel models and mediating effect models for empirical analysis.The findings reveal that green finance indirectly fosters agricultural green development by driving agricultural technological progress.This promoting effect is significant,with the mediating effect accounting for 3.67%.Based on these results,policy recommendations are proposed:expanding the coverage of green finance and constructing a diversified product system;comprehensively promoting agricultural technological innovation and mechanization development;and coordinating and integrating green financial resources to facilitate agricultural green transformation tailored to local conditions.展开更多
The development of skeletal muscle are complicated processes involving genes responsible for proper muscle morphology,contractility,cell proliferation,differentiation,interactions,migration,and death.The three-dimensi...The development of skeletal muscle are complicated processes involving genes responsible for proper muscle morphology,contractility,cell proliferation,differentiation,interactions,migration,and death.The three-dimensional chromatin architecture of skeletal muscle development has not been studied intensively although dynamic transcriptional regulation during differentiation of muscle cells is one of the most deeply studied processes.The RNA-seq was used to analyze the transcriptome pattern during chicken muscle development across 12 stages.Hi-C was used to build chromatin architectures during four representative stages.Ch IP-seq was conducted to identify enhancers and promoters in these four stages,which are occupied by histone H3K27ac and H3K4me3 peaks.Results show that large-scale genome architecture changes are mostly unidirectional,and coupled by complex on/off dynamic patterns of gene expression.Specifically,we observed 258.30 Mb of the genome undergoing A/B compartment switching.Notable alterations(316.57 Mb)of interaction frequencies within TADs were observed.Substantial aging-associated genes exhibited ascending connectivity with the compartment transition from repressive to active status during muscle development.Some muscle-related gene promoters that interacted with active enhancers during development,and some myopathy/aging-associated genes that were activated in aging muscle were founded.These results provide key insights into skeletal muscle development in vivo,and offer a valuable resource that allows in-depth functional characterization of candidate genes.展开更多
The International Standardization Youth Star Competition is held for three consecutive years.We have witnessed continuous improvement in the competition each year,which is a result of our collective efforts.
N6-methyladenosine(m^(6)A)modification,the most abundant internal modification in messenger RNA(mRNA)and long non-coding RNA(lncRNA),has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes.While...N6-methyladenosine(m^(6)A)modification,the most abundant internal modification in messenger RNA(mRNA)and long non-coding RNA(lncRNA),has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes.While the importance of m^(6)A modification in various biological processes has been recognized,a comprehensive understanding of its diverse roles in plant biology and agricultural applications remains fragmented.This review analyzes recent advances inm^(6)A modification's biological functions in plants.m^(6)A modification plays crucial roles in multiple aspects of plant life,including seed germination,organ development,and reproductive structure formation.Furthermore,m^(6)A has been found to significantly influence plant responses to environmental stresses,including salt,drought,temperature,and heavy metal exposure.We also uncover m^(6)A involvement in important agricultural traits.This review provides insights into the mechanistic understanding of m^(6)A modification in plants and highlights its applications in agricultural improvement,offering a foundation for future research in crop enhancement and stress resistance.展开更多
In the evolving global economy,China’s Outward Foreign Direct Investment(OFDI)holds increasing significance,specially within the context of the Belt and Road Initiative(BRI).Despite earlier studies have acknowledged ...In the evolving global economy,China’s Outward Foreign Direct Investment(OFDI)holds increasing significance,specially within the context of the Belt and Road Initiative(BRI).Despite earlier studies have acknowledged the role of governance quality in at-tracting Chinese OFDI,their explanatory capacity regarding human development has not received sufficient attention.This study ad-dresses this gap,investigating the relationship between Chinese OFDI and human development,emphasizing the governance quality’s moderating role.Using data from 122 BRI countries from 2004 to 2021,we employed the Panel Corrected Standard Error model through Prais-Winsten regression,complimented by robustness check via the Spatial Durbin Model.Our analysis revealed a significant positive relationship between Chinese OFDI and human development in BRI countries,indicating that Chinese investments act as cata-lysts for improved well-being.More importantly,governance quality plays a vital role in shaping this relationship,revealing that effect-ive governance enhanced the human development outcomes of OFDI.Post-hoc analysis of governance indicators,both as a composite index and individual dimensions,supported this finding.Regional heterogeneity analysis further showed that Chinese OFDI has stronger effects on Human Development Index(HDI)in Asia and Africa compared to Europe,Latin America,and Oceania.However,the moder-ating effect of governance quality seemed more prominent in Oceania and Latin America,indicating its role in fostering the benefits of Chinese investments in these regions.These findings hold implications for academia and policy,emphasizing the need for transparent,accountable,and effective governance to drive sustainable and inclusive human development within the BRI framework.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.32160172)the Key Science-Technology Project of Inner Mongolia(2023KYPT0010)+1 种基金the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Grant No.2025QN03006)the 2023 Inner Mongolia Public Institution High-Level Talent Introduction Scientific Research Support Project.
文摘Environmental DNA(eDNA)technology has revolutionized biodiversity monitoring with its non-invasive,sensitive,and cost-efficient approach.This paper systematically reviews eDNA advancements,examining its applications in aquatic and terrestrial ecosystems and assessing China’s standardization progress.It delineates four developmental phases from single-species detection to high-throughput sequencing,and highlights China’s contribution to the development of technical standards.While significant progress has been made,challenges persist in quantitative accuracy,methodological consistency,and large-scale implementation.Future efforts should prioritize enhanced standardization,improved quantification techniques,broader applications,and international collaboration to drive innovation in eDNA technology.
基金Supported by the National Natural Science Foundation of China(42477521).
文摘In this paper,the research status of industrial ecology abroad is briefly introduced,and the development status of industrial ecology in China is summarized and evaluated,including research content,methods,applications,etc.At the same time,combined with the current needs of China s economic-social development,it looks forward to the future development direction and application prospects of industrial ecology.In the coming period,research on green transformation technologies for industrial structure and production methods,carbon peak routes and carbon reduction implementation paths for industrial systems,key technologies for adapting to climate change and achieving carbon peak and carbon neutrality in priority areas,cross regional collaborative technologies for industrial chains,regional energy resource optimization and allocation technologies,efficient industrial agglomeration and collaboration technologies,multimedia composite pollution collaborative governance technologies,collaborative governance technologies for pollution and carbon reduction,multimedia comprehensive governance of multiple pollutants,and empirical theoretical systems of industrial ecology with Chinese characteristics will be the direction of industrial ecology research in China.
基金the support of EPIC - Energy Production Innovation Center, hosted by the University of Campinas (UNICAMP) and sponsored by Equinor Brazil and FAPESP - Sao Paulo Research Foundation (2021/04878- 7 and 2017/15736-3)financed in part by the Coordenacao de Aperfeicoamento de Pessoal de Nível Superior Brasil (CAPES) - Financing Code 001
文摘In the area of reservoir engineering,the optimization of oil and gas production is a complex task involving a myriad of interconnected decision variables shaping the production system's infrastructure.Traditionally,this optimization process was centered on a single objective,such as net present value,return on investment,cumulative oil production,or cumulative water production.However,the inherent complexity of reservoir exploration necessitates a departure from this single-objective approach.Mul-tiple conflicting production and economic indicators must now be considered to enable more precise and robust decision-making.In response to this challenge,researchers have embarked on a journey to explore field development optimization of multiple conflicting criteria,employing the formidable tools of multi-objective optimization algorithms.These algorithms delve into the intricate terrain of production strategy design,seeking to strike a delicate balance between the often-contrasting objectives.Over the years,a plethora of these algorithms have emerged,ranging from a priori methods to a posteriori approach,each offering unique insights and capabilities.This survey endeavors to encapsulate,catego-rize,and scrutinize these invaluable contributions to field development optimization,which grapple with the complexities of multiple conflicting objective functions.Beyond the overview of existing methodologies,we delve into the persisting challenges faced by researchers and practitioners alike.Notably,the application of multi-objective optimization techniques to production optimization is hin-dered by the resource-intensive nature of reservoir simulation,especially when confronted with inherent uncertainties.As a result of this survey,emerging opportunities have been identified that will serve as catalysts for pivotal research endeavors in the future.As intelligent and more efficient algo-rithms continue to evolve,the potential for addressing hitherto insurmountable field development optimization obstacles becomes increasingly viable.This discussion on future prospects aims to inspire critical research,guiding the way toward innovative solutions in the ever-evolving landscape of oil and gas production optimization.
基金Supported by Research Project on Food Detection Technology Innovation and Standard Integration 2024(YNXM-2024-FW-019).
文摘This paper investigates and analyzes the general situation of the tomato seed production industry in Lintong District,Xi'an City.Development strategies and suggestions are proposed to address existing problems.These include strengthening technological innovation and variety R&D,promoting industrial standardization and intelligent upgrading,enhancing brand building and market expansion,improving policy support and industrial chain coordination,strengthening intellectual property protection and talent cultivation,and expanding sales channels to promote industrial transformation and upgrading.
基金supported by the National Natural Science Foundation of China(82225049,72104155)the Sichuan Provincial Central Government Guides Local Science and Technology Development Special Project(2022ZYD0127)the 1·3·5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYGD23004).
文摘Background:In recent years,there has been a growing trend in the utilization of observational studies that make use of routinely collected healthcare data(RCD).These studies rely on algorithms to identify specific health conditions(e.g.,diabetes or sepsis)for statistical analyses.However,there has been substantial variation in the algorithm development and validation,leading to frequently suboptimal performance and posing a significant threat to the validity of study findings.Unfortunately,these issues are often overlooked.Methods:We systematically developed guidance for the development,validation,and evaluation of algorithms designed to identify health status(DEVELOP-RCD).Our initial efforts involved conducting both a narrative review and a systematic review of published studies on the concepts and methodological issues related to algorithm development,validation,and evaluation.Subsequently,we conducted an empirical study on an algorithm for identifying sepsis.Based on these findings,we formulated specific workflow and recommendations for algorithm development,validation,and evaluation within the guidance.Finally,the guidance underwent independent review by a panel of 20 external experts who then convened a consensus meeting to finalize it.Results:A standardized workflow for algorithm development,validation,and evaluation was established.Guided by specific health status considerations,the workflow comprises four integrated steps:assessing an existing algorithm’s suitability for the target health status;developing a new algorithm using recommended methods;validating the algorithm using prescribed performance measures;and evaluating the impact of the algorithm on study results.Additionally,13 good practice recommendations were formulated with detailed explanations.Furthermore,a practical study on sepsis identification was included to demonstrate the application of this guidance.Conclusions:The establishment of guidance is intended to aid researchers and clinicians in the appropriate and accurate development and application of algorithms for identifying health status from RCD.This guidance has the potential to enhance the credibility of findings from observational studies involving RCD.
基金Supported by 2025 Guizhou Theoretical Innovation Project of Guizhou Federation of Social Sciences Associations(GZLCLH-2025-110).
文摘This paper focuses on Guizhou's health and wellness industry and rural revitalization,delving deeply into their foundational theories,historical evolution,current status,technological progress,future prospects,and points of contention.Through a comprehensive analysis of relevant references,it elaborates on the definition of the health and wellness industry and Guizhou's geographical advantages,reviews the background and implementation pathways of the rural revitalization strategy,and analyzes the mechanism for their synergistic development.It reviews the respective development trajectories of Guizhou's health and wellness industry and rural revitalization,as well as their integration process,analyzes the current status and market demand,the challenges faced,and the status of their integration.It explores the application of technological innovations,strategies for technology empowerment,and cases of technology integration,forecasts future development trends,plans,and paths for integrated development,and discusses contentious points such as benefit distribution,environmental protection,and policy coordination,aiming to provide comprehensive theoretical and practical references for the further development of Guizhou's health and wellness industry and rural revitalization.
基金Supported by Binzhou Social Sciences Planning Project in 2024(24-SKGH-051)Binzhou Comprehensive Experimental Station Project of Shandong Provincial Forage Industry Technology System(SDAIT-23-10).
文摘This paper investigated and analyzed the conservation and utilization of four local livestock breeds in Binzhou City:Wadi Sheep,Bohai Black Cattle,Wudi Donkey,and Lubei White Goat.Shortcomings in the protection and utilization of local germplasm resources were pointed out,and strategies and recommendations were proposed to promote high-quality development of livestock and poultry genetic resources in Binzhou,including building a solid germplasm foundation,standardizing production,and driving innovation.This paper provides references for the conservation,development,and utilization of local genetic resources in Binzhou City.
文摘The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to more than 30% of the world's population,predominantly in developing countries where per capita farmland and food supply are only 40% of those in developed nations(FAO 2018).Meeting the Zero Hunger target amid ongoing population growth in these regions requires a substantial increase in agricultural production while minimizing soil degradation and adverse ecological impacts.This challenge is shared by many countries across South Asia,Africa,and Central and South America.
文摘Innovation and Development Policy,简称“IDP”,中文名:《创新与发展政策(英文)》,是由中国科学院主管,中国科学院科技战略咨询研究院、中国科学学与科技政策研究会共同主办,国内外发行(ISSN:2096-5141,CN:10-1513/D)的英文国际期刊。目前期刊每年出版两期。已发表论文在期刊网站可以自由获取,http://idp-journal.casisd.cn/browse/al/al2019/。
文摘Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.Young students,with their active and vibrant minds,represent the future and hope of standardization.
文摘China is carving out a distinctive development path which features urban-rural integration.This approach has not only yielded tangible results domestically but also drawn the attention of other countries.
文摘Hepatocellular carcinoma presents with three distinct immune phenotypes,including immune-desert,immune-excluded,and immune-inflamed,indicating various treatment responses and prognostic outcomes.The clinical application of multi-omics parameters is still restricted by the expensive and less accessible assays,although they accurately reflect immune status.A comprehensive evaluation framework based on“easy-to-obtain”multi-model clinical parameters is urgently required,incorporating clinical features to establish baseline patient profiles and disease staging;routine blood tests assessing systemic metabolic and functional status;immune cell subsets quantifying subcluster dynamics;imaging features delineating tumor morphology,spatial configuration,and perilesional anatomical relationships;immunohistochemical markers positioning qualitative and quantitative detection of tumor antigens from the cellular and molecular level.This integrated phenomic approach aims to improve prognostic stratification and clinical decision-making in hepatocellular carcinoma management conveniently and practically.
文摘To advance intelligent construction,standards must come first.The Ministry of Housing and Urban-Rural Development has issued the List for Replicable Experience and Practices for Developing Intelligent Construction four times successively and the Technical Guidelines for Intelligent Construction(Trial).
文摘China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have always been a priority in national development.At its fourth plenary session held in October 2025,the 20th Central Committee of the Communist Party of China(CPC)once again emphasized the need to accelerate agricultural and rural modernization,and advance all-around rural revitalization over the next five years.
文摘Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs.
基金Supported by Zhejiang Provincial Philosophy and Social Sciences Planning Project(23FNSQ58YB).
文摘Against the backdrop of China s accelerated green development and its pursuit of the"dual carbon"goals,green finance,as a crucial instrument for the rational allocation of resources,plays a significant role in promoting agricultural green transformation.Taking Henan Province as a case study,this research employs panel data from 18 prefecture-level cities spanning 2014 to 2023,utilizing dynamic panel models and mediating effect models for empirical analysis.The findings reveal that green finance indirectly fosters agricultural green development by driving agricultural technological progress.This promoting effect is significant,with the mediating effect accounting for 3.67%.Based on these results,policy recommendations are proposed:expanding the coverage of green finance and constructing a diversified product system;comprehensively promoting agricultural technological innovation and mechanization development;and coordinating and integrating green financial resources to facilitate agricultural green transformation tailored to local conditions.
基金supported by the National Key R&D Program of China(2023YFD1300040 and 2022YFF1000100)the Sichuan Science and Technology Program,China(2022NSFSC0132,2021YFYZ0009 and 2022JDJQ0054)the National Natural Science Foundation of China(32225046)。
文摘The development of skeletal muscle are complicated processes involving genes responsible for proper muscle morphology,contractility,cell proliferation,differentiation,interactions,migration,and death.The three-dimensional chromatin architecture of skeletal muscle development has not been studied intensively although dynamic transcriptional regulation during differentiation of muscle cells is one of the most deeply studied processes.The RNA-seq was used to analyze the transcriptome pattern during chicken muscle development across 12 stages.Hi-C was used to build chromatin architectures during four representative stages.Ch IP-seq was conducted to identify enhancers and promoters in these four stages,which are occupied by histone H3K27ac and H3K4me3 peaks.Results show that large-scale genome architecture changes are mostly unidirectional,and coupled by complex on/off dynamic patterns of gene expression.Specifically,we observed 258.30 Mb of the genome undergoing A/B compartment switching.Notable alterations(316.57 Mb)of interaction frequencies within TADs were observed.Substantial aging-associated genes exhibited ascending connectivity with the compartment transition from repressive to active status during muscle development.Some muscle-related gene promoters that interacted with active enhancers during development,and some myopathy/aging-associated genes that were activated in aging muscle were founded.These results provide key insights into skeletal muscle development in vivo,and offer a valuable resource that allows in-depth functional characterization of candidate genes.
文摘The International Standardization Youth Star Competition is held for three consecutive years.We have witnessed continuous improvement in the competition each year,which is a result of our collective efforts.
基金supported by the National Nature Science Foundation of China(Grant No.31660568)Guangxi Science and Technology major project(Grant No.GuikeAA22068088)+2 种基金start-up funding for introduced talents in Guangxi University,the Guangxi Colleges and Universities Young and Middle-aged Teachers'Basic Scientific Research Ability Improvement Project(Grant No.2024KY0010)Guangxi Graduate Education Innovation Program(Grant No.YCSW2024093)the Guangxi University Student Innovation and Entrepreneurship Training Program Funding Project(Grant Nos.202310593704,202310593714,202410953044S).
文摘N6-methyladenosine(m^(6)A)modification,the most abundant internal modification in messenger RNA(mRNA)and long non-coding RNA(lncRNA),has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes.While the importance of m^(6)A modification in various biological processes has been recognized,a comprehensive understanding of its diverse roles in plant biology and agricultural applications remains fragmented.This review analyzes recent advances inm^(6)A modification's biological functions in plants.m^(6)A modification plays crucial roles in multiple aspects of plant life,including seed germination,organ development,and reproductive structure formation.Furthermore,m^(6)A has been found to significantly influence plant responses to environmental stresses,including salt,drought,temperature,and heavy metal exposure.We also uncover m^(6)A involvement in important agricultural traits.This review provides insights into the mechanistic understanding of m^(6)A modification in plants and highlights its applications in agricultural improvement,offering a foundation for future research in crop enhancement and stress resistance.
基金Under the auspices of Fundamental Research Funds for the Central Universities,Zhongnan University of Economics and Law,China(No.2722021EG001)。
文摘In the evolving global economy,China’s Outward Foreign Direct Investment(OFDI)holds increasing significance,specially within the context of the Belt and Road Initiative(BRI).Despite earlier studies have acknowledged the role of governance quality in at-tracting Chinese OFDI,their explanatory capacity regarding human development has not received sufficient attention.This study ad-dresses this gap,investigating the relationship between Chinese OFDI and human development,emphasizing the governance quality’s moderating role.Using data from 122 BRI countries from 2004 to 2021,we employed the Panel Corrected Standard Error model through Prais-Winsten regression,complimented by robustness check via the Spatial Durbin Model.Our analysis revealed a significant positive relationship between Chinese OFDI and human development in BRI countries,indicating that Chinese investments act as cata-lysts for improved well-being.More importantly,governance quality plays a vital role in shaping this relationship,revealing that effect-ive governance enhanced the human development outcomes of OFDI.Post-hoc analysis of governance indicators,both as a composite index and individual dimensions,supported this finding.Regional heterogeneity analysis further showed that Chinese OFDI has stronger effects on Human Development Index(HDI)in Asia and Africa compared to Europe,Latin America,and Oceania.However,the moder-ating effect of governance quality seemed more prominent in Oceania and Latin America,indicating its role in fostering the benefits of Chinese investments in these regions.These findings hold implications for academia and policy,emphasizing the need for transparent,accountable,and effective governance to drive sustainable and inclusive human development within the BRI framework.
