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Remediation of characteristic contaminants in groundwater of chemical industrial by the activation of PMS:Recent developments and challenges-a mini-review
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作者 Yingnan Duan Jinyu Liu +3 位作者 Qian Liu Tianhao Li Hexiang Zhao Zhurui Shen 《Chinese Chemical Letters》 2026年第1期177-185,共9页
Groundwater is a key part of the terrestrial ecosystem,but it is vulnerable to pollution in the context of chemical industry development.Treating contaminated groundwater is challenging due to its stable water quality... Groundwater is a key part of the terrestrial ecosystem,but it is vulnerable to pollution in the context of chemical industry development.Treating contaminated groundwater is challenging due to its stable water quality,hidden contamination,and complex treatment requirements.Current research focuses on advanced treatment technologies,among which the advanced oxidation process(AOPs) of peroxomonosulfate(PMS) has great potential.Although there are many reviews of PMS-based AOP,most of them focus on surface water.This review aims to explore the activation reaction of PMS to groundwater by in-situ chemical oxidation(ISCO) technology,further study the reaction mechanism,compare the treatment effect of characteristic pollutants in the groundwater of the chemical industry park,propose new activation methods and catalyst selection,and provide guidance for future groundwater treatment research. 展开更多
关键词 Advanced oxidation processes(AOPs) In-situ chemical oxidation PMS Groundwater contamination characteristic pollutants
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Development Path with Asian Characteristics: Asia's Answer amid Once-in-a-Century Changes
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作者 Liu Jianchao 《Contemporary World》 2025年第1期2-4,共3页
At the beginning of the new year, we celebrate the arrival of 2025. Unfortunately, not everyone in the world shares such joy and peace. Many, instead, are mired in turmoil, conflict, and bloodshed. In 2024 alone, over... At the beginning of the new year, we celebrate the arrival of 2025. Unfortunately, not everyone in the world shares such joy and peace. Many, instead, are mired in turmoil, conflict, and bloodshed. In 2024 alone, over 233,000 lives perished in the flames of war. In many ways, Asia has been fortunate. Since the end of World War Ⅱ, we in Asia have largely enjoyed peace and stability, making steady progress towards prosperity through hard work. 展开更多
关键词 Asian characteristics development PROSPERITY WAR conflict PEACE stability
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Research on the Construction of Characteristic Major Groups in Private Vocational Undergraduate Colleges and the Coordinated Development of Regional Industries
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作者 Jiong He Jingying Wang Tianshuo Jiang 《Journal of Contemporary Educational Research》 2025年第11期298-305,共8页
In the context of national efforts to promote high-quality development of vocational education and deepen industry-education integration,private vocational undergraduate institutions serve as crucial platforms bridgin... In the context of national efforts to promote high-quality development of vocational education and deepen industry-education integration,private vocational undergraduate institutions serve as crucial platforms bridging the cultivation of high-level technical and skilled talents with regional industrial development.The alignment between their distinctive specialty clusters and regional industrial synergy directly impacts talent development quality and regional economic efficiency.This paper analyzes the inherent logic of coordinated development between specialty clusters and regional industries,leveraging the flexible operational mechanisms and direct industry connections of private vocational institutions.It identifies current challenges,including“inaccurate demand alignment,insufficient resource integration,and loose interest coordination,”and proposes four strategic dimensions:establishing collaborative research mechanisms,optimizing cluster layouts,deepening industry-education integration,and improving support systems.These recommendations provide actionable references for advancing high-quality coordinated development between private vocational institutions and regional industries. 展开更多
关键词 Private vocational undergraduate colleges characteristic major groups Regional industries Coordinated development Industry-education integration
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The geochemical,pore development and water-bearing characteristics of deep and ultra-deep marine shales and their effects on gas content:New implications from the shales of the first Lower Cambrian highyield gas well(Z201)in China
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作者 Hai-Tao Gao Peng Cheng +5 位作者 Wei Wu Chao Luo Liang Xu Teng-Fei Li Hai-Feng Gai Hui Tian 《Petroleum Science》 2025年第5期1839-1853,共15页
The Lower Cambrian shales in the Sichuan Basin are considered one of the most promising shale gas resources in China.However,large-scale commercial development has not been achieved due to the relatively low and signi... The Lower Cambrian shales in the Sichuan Basin are considered one of the most promising shale gas resources in China.However,large-scale commercial development has not been achieved due to the relatively low and significantly variable gas contents of the drilled shales.Excitingly,the first major breakthrough in deep and ultra-deep Lower Cambrian shale gas was made recently in the well Z201 in the southern Sichuan Basin,with a gas yield exceeding 73×10^(4)m^(3)/d.The success of well Z201 provides a favorable geological case to reveal the distinct enrichment mechanism of deep and ultra-deep Lower Cambrian shale gas.In this study,at drilling site of well Z201,fresh shale core samples with different gasin-place contents were collected,and their geochemical,pore development and water-bearing characteristics were analyzed systematically.The results showed that the Z201 organic-rich shales reached an overmature stage,with an average Raman maturity of 3.70%.The Z201 shales with high gas-in-place contents are mainly located in the Qiongzhusi 12section and the upper Qiongzhusi 11section,with an average gas-in-place content of 10.08 cm^(3)/g.Compared to the shales with low gas-in-place contents,the shales with high gas-in-place contents exhibit higher total organic carbon contents,greater porosities,and lower water saturations,providing more effective pore spaces for shale gas enrichment.The effective pore structures of the deep and ultra-deep Lower Cambrian shales are the primary factors affecting their gas-in-place contents.Similar to the shales with high gas-in-place contents of well Z201,the deep and ultra-deep Lower Cambrian shales in the Mianyang-Changning intracratonic sag,especially in the Ziyang area,generally developed in deep-water shelf facies with high total organic carbon contents and thick sedimentary thickness,providing favorable conditions for the development and preservation of effective pores.Therefore,they are the most promising targets for Lower Cambrian shale gas exploration. 展开更多
关键词 The Lower Cambrian Deep and ultra-deep shales Pore structures Water-bearing characteristics Geochemical characteristics Gas content
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mTORC1 and mTORC2 synergy in human neural development, disease, and regeneration 被引量:1
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作者 Navroop K.Dhaliwal Julien Muffat Yun Li 《Neural Regeneration Research》 2026年第4期1552-1553,共2页
The mechanistic target of rapamycin(m TOR) is a serine/threonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regul... The mechanistic target of rapamycin(m TOR) is a serine/threonine kinase that plays a pivotal role in cellular growth, proliferation, survival, and metabolism. In the central nervous system(CNS), the mTOR pathway regulates diverse aspects of neural development and function. Genetic mutations within the m TOR pathway lead to severe neurodevelopmental disorders, collectively known as “mTORopathies”(Crino, 2020). Dysfunctions of m TOR, including both its hyperactivation and hypoactivation, have also been implicated in a wide spectrum of other neurodevelopmental and neurodegenerative conditions, highlighting its importance in CNS health. 展开更多
关键词 m tor neural development mtorc central nervous system cns mtor neurodevelopmental disorders neurodegenerative conditions
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Sperm RNA quantity and PRM1, PRM2, and TH2B transcript levels reflect sperm characteristics and early embryonic development
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作者 Bilge Ozsait-Selcuk Sibel Bulgurcuoglu-Kuran +3 位作者 Dilek Sever-Kaya Neslihan Coban Gulsen Aktan Ates Kadioglu 《Asian Journal of Andrology》 2025年第1期76-83,共8页
Spermatozoa have a highly complex RNA profile.Several of these transcripts are suggested as biomarkers for male infertility and contribute to early development.To analyze the differences between sperm RNA quantity and... Spermatozoa have a highly complex RNA profile.Several of these transcripts are suggested as biomarkers for male infertility and contribute to early development.To analyze the differences between sperm RNA quantity and expression of protamine(PRM1 and PRM2)and testis-specific histone 2B(TH2B)genes,spermatozoa from 33 patients who enrolled in assisted reproduction treatment(ART)program were analyzed.Sperm RNA of teratozoospermic(T),oligoteratozoospermic(OT),and normozoospermic(N)samples was extracted,and the differences in transcript levels among the study groups were analyzed by quantitative real-time polymerase chain reaction(qRT-PCR).The correlations of total RNA per spermatozoon and the expression of the transcripts were evaluated in relation to sperm characteristics and preimplantation embryo development.The mean(±standard deviation)RNA amount per spermatozoon was 28.48(±23.03)femtogram in the overall group and was significantly higher in the OT group than that in N and T groups.Total sperm RNA and gene expression of PRM1 and PRM2 genes were related to preimplantation embryo development and developmental arrest.Specific sperm characteristics were correlated with the expressions of PRM1,PRM2,or TH2B genes.We conclude that the sperm RNA amount and composition are important factors and might influence early embryonic development and also differ in different cases of male infertility. 展开更多
关键词 embryonic development PRM1 PRM2 RNA SPERMATOZOA TH2B
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Characteristics of pore-throat structures in volatile oil reservoirs and strategies for optimal development
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作者 Ying Tang Zhao Li +3 位作者 Shuai Yin Ruifei Wang Kai Feng Tao Jiang 《Energy Geoscience》 2025年第3期121-132,共12页
The third member of Shahejie Formation(also referred to as Sha 3 Member)in Dongpu Depression,China,a volatile,low-permeability oil reservoir with complex fluid compositions,is subjected to high temperature and high pr... The third member of Shahejie Formation(also referred to as Sha 3 Member)in Dongpu Depression,China,a volatile,low-permeability oil reservoir with complex fluid compositions,is subjected to high temperature and high pressure(HPHT),which poses significant challenges to conventional water injection.To elucidate flow mechanisms and optimize development strategies,this study integrates constant-rate mercury injection(CRMI),nuclear magnetic resonance(NMR),and HPHT three-phase oil/gas/water relative permeability experiments to analyze pore-throat structures,movable fluid characteristics,and relative permeability.The CRMI results indicate that the reservoir exhibits low porosity and low permeability,with dominant throat radius ranging from 0.6 to 5.0μm,and mean pore-throat radius ratio ranging from 40.303 to 278.320,demonstrating significant microscopic heterogeneity.The NMR results reveal that water-alternating-gas(WAG)injection enhances oil recovery by 16.28%(Sample W1)and 13.52%(Sample W2)compared to conventional water injection,primarily due to the gas phase's low viscosity and high mobility,enabling access to micropores unreachable by water phases.The HPHT three-phase relative permeability tests demonstrate positive correlations between saturation and relative permeability,with oil permeability significantly influenced by three-phase saturation and rock wettability.These findings establish a microscopic seepage model for optimizing enhanced oil recovery(EOR)strategies in volatile reservoirs. 展开更多
关键词 Dongpu Depression Volatile reservoir Pore-throat structure Three-phase relative permeability development strategy
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Pollution Characteristics and Sources of Heavy Metal in the Soil Around a Concentrated Lead and Zinc Mining Area in Guangxi
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作者 LU Yuqiu TANG Xiaohui +5 位作者 XIN Meifen HUANG Yanhong LI Yang WU Hao LUO Dongyuan ZHOU Lang 《有色金属(中英文)》 北大核心 2026年第2期392-411,共20页
39 soil samples surrounding a lead-zinc mining area in Guangxi were collected,and the contents of Pb,Hg,Cd,Cr,As,Cu,Zn,and Ni were determined to investigate the pollution characteristics and sources of heavy metals.Ar... 39 soil samples surrounding a lead-zinc mining area in Guangxi were collected,and the contents of Pb,Hg,Cd,Cr,As,Cu,Zn,and Ni were determined to investigate the pollution characteristics and sources of heavy metals.ArcGIS inverse distance weight difference method was used to analyze the characteristics of pollution distribution,and single-factor pollution index,Nemerow comprehensive pollution index,ground accumulation index,and potential ecological risk index were selected to evaluate the characteristics of heavy metal pollution.Based on correlation analysis,the absolute principal component-multiple linear regression(APCS-MLR)and positive definite matrix factorization(PMF)models were used to analyze the sources of soil heavy metals.The results showed that the average concentrations of all eight heavy metals exceeded both national and Guangxi soil background values.Hg,Cd,and Zn exhibited high variation(greater than 0.5),indicating significant external disturbances,and their spatial distribution was closely related to mining activity locations.The single-factor pollution index evaluation indicated varying degrees of pollution risk for Cd,Zn,and As,with Cd and Zn being the most severe pollutants,as 69.23%and 30.77%of the samples fell into the moderate pollution or higher category.The geoaccumulation index analysis ranked the mean pollution levels of the eight elements as follows:Zn>Cd>Ni>Pb>Cu>Cr>Hg>As,with Cd and Zn showing the most severe contamination,and 51.28%of the samples exhibiting moderate or higher pollution levels.The Nemerow comprehensive pollution index evaluation showed that 74.35%of soil samples were classified as moderate to heavy pollution.The potential ecological risk index assessment indicated significant ecological risks posed by Cd and Zn,with 82.05%and 5.12%of the samples classified as causing strong to extreme ecological risks,respectively.The source apportionment analysis revealed minor differences between the two models.The APCS-MLR model identified three pollution sources and their contribution rates:anthropogenic mining sources(31.13%),parent material sources(40.38%),and unidentified sources(28.49%).The PMF model identified three pollution sources with contribution rates of anthropogenic mining sources(26.10%),parent material sources(46.96%),and a combined traffic and agricultural source(26.61%).Pb,Hg,Cd,and Zn mainly originated from mining activities;Cr,As,and Ni were primarily derived from the parent material,while Cu was predominantly attributed to traffic and agricultural sources.These findings provide a scientific basis for the prevention and control of heavy metal pollution in mining areas. 展开更多
关键词 mining area soil heavy metals pollution characteristics risk assessment source apportionment
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Spatiotemporal Evolution Characteristics and Impact Factors of Urbanrural Integrated Development in China
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作者 LI Li YANG Lan +2 位作者 WANG Hao YANG Shuang YAN Zhihan 《Chinese Geographical Science》 2025年第4期802-818,共17页
Understanding the urban-rural development mechanism is critical for implementing rural revival and new-type urbanization.However,it remains a challenge to quantify the urban-rural integrated development level(URIDL)an... Understanding the urban-rural development mechanism is critical for implementing rural revival and new-type urbanization.However,it remains a challenge to quantify the urban-rural integrated development level(URIDL)and its impact factors.Hence,we constructed an assessment system for the URIDL from spatial,economic,social,life,and ecological integration.The spatial autocorrelation and Spearman rank correlation coefficients were used to assess the spatiotemporal variation of the URIDL and the trade-off synergistic relationship among the subsystems at the provincial scale in China using socio-economic statistical data from 2000 to 2020.A spatial panel quantile regression model was used to analyze the driving mechanism.The results showed that the URIDL of China increased by 0.19%from 2000 to 2020,and a high-high(H-H)spatial agglomeration pattern occurred in the Yangtze River Delta and the Beijing-Tianjin-Hebei regions.Spatial integration significantly contributed to the other subsystems,whereas economic integration had a significant negative impact on the other subsystems in the eastern coastal and southwestern regions.Per capita Gross Domestic Product(GDP)improved the URIDL,whereas other factors,such as fiscal revenue decentralization,had inhibiting effects.Notably,the impact of factors on URIDL varies across different quantiles.Finally,we proposed policy recommendations for differentiated improvement of URIDL based on its evolution and regional development level during the research period. 展开更多
关键词 urban-rural integrated development level(URIDL) spatial pattern spatial autocorrelation spatial panel quantile regression China
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Ecosystem management and agricultural green development in subtropical regions
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作者 Jinshui Wu Tony G.O’Donnell +4 位作者 Andrew Macrae Hongsong Chen Weiguo Cheng Zhihong Xu Zhengmiao Deng 《Journal of Integrative Agriculture》 2026年第2期399-401,共3页
The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to ... The United Nations Sustainable Development Goal(SDG) 2 aims to achieve Zero Hunger by 2030.However,global hunger and food insecurity have continued to rise at an alarming rate(UN 2023).Subtropical regions are home to more than 30% of the world's population,predominantly in developing countries where per capita farmland and food supply are only 40% of those in developed nations(FAO 2018).Meeting the Zero Hunger target amid ongoing population growth in these regions requires a substantial increase in agricultural production while minimizing soil degradation and adverse ecological impacts.This challenge is shared by many countries across South Asia,Africa,and Central and South America. 展开更多
关键词 ecosystem management developing countries subtropical regions sustainable development goal agricultural green development zero hunger sustainable development goal sdg population growth
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Innovation and Development Policy(中文名:《创新与发展政策(英文)》)征稿启事
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《科研管理》 北大核心 2026年第1期F0004-F0004,共1页
Innovation and Development Policy,简称“IDP”,中文名:《创新与发展政策(英文)》,是由中国科学院主管,中国科学院科技战略咨询研究院、中国科学学与科技政策研究会共同主办,国内外发行(ISSN:2096-5141,CN:10-1513/D)的英文国际期刊... Innovation and Development Policy,简称“IDP”,中文名:《创新与发展政策(英文)》,是由中国科学院主管,中国科学院科技战略咨询研究院、中国科学学与科技政策研究会共同主办,国内外发行(ISSN:2096-5141,CN:10-1513/D)的英文国际期刊。目前期刊每年出版两期。已发表论文在期刊网站可以自由获取,http://idp-journal.casisd.cn/browse/al/al2019/。 展开更多
关键词 创新与发展政策 Innovation and development Policy
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Guiding the younger generation to explore new scenarios for participating in standards development and application
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作者 Li Zhiping 《China Standardization》 2026年第1期43-44,共2页
Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.You... Standards are the common language that consolidates global consensus and builds the most solid foundation for international partnerships.They are the cornerstone for global sustainable and high-quality development.Young students,with their active and vibrant minds,represent the future and hope of standardization. 展开更多
关键词 standards development sustainable development application standards international partnerships high quality development consolidates global consensus younger generation common language
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China’s Urban-Rural Integration:A Global Perspective on Sustainable Development
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作者 XIA YUANYUAN 《China Today》 2026年第1期36-38,共3页
China is carving out a distinctive development path which features urban-rural integration.This approach has not only yielded tangible results domestically but also drawn the attention of other countries.
关键词 sustainable development urban rural integration China development path
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3D morphological characteristics of shrinkage porosities and their relationship with microstructures in Mg−12Al magnesium alloy
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作者 Chuang-ming LI Ang ZHANG +6 位作者 Yong-feng LI Heng-rui HU He LIU Yu-yang GAO Zhi-hua DONG Bin JIANG Fu-sheng PAN 《Transactions of Nonferrous Metals Society of China》 2026年第1期96-111,共16页
The dependence of shrinkage porosities on microstructure characteristics of Mg−12Al alloy was investigated.The distribution,morphology,size,and number density of shrinkage porosities were analyzed under different cool... The dependence of shrinkage porosities on microstructure characteristics of Mg−12Al alloy was investigated.The distribution,morphology,size,and number density of shrinkage porosities were analyzed under different cooling rates.The relationship between shrinkage porosities and microstructure characteristics was discussed in terms of temperature conditions,feeding channel characteristics,and feeding capacity.Further,the feeding behavior of the residual liquid phase in the solid skeleton was quantified by introducing permeability.Results show a strong correlation between the solid microstructure skeleton and shrinkage porosity characteristics.An increase in permeability corresponds to a declining number density of shrinkage porosities.This study aims to provide a more complete understanding how to reduce shrinkage porosities by controlling microstructure characteristics. 展开更多
关键词 Mg−12Al alloy shrinkage porosity SOLIDIFICATION microstructure characteristics morphological characteristics
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Powering Local Growth China's counties are on track to witness high-quality development rooted in local conditions
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作者 Tu Shengwei 《China Report ASEAN》 2026年第1期50-51,共2页
County economies form a distinctive,integrated regional economic structure.Their growth is shaped by specific social and historical conditions and,in turn,influences many aspects of wider economic and social developme... County economies form a distinctive,integrated regional economic structure.Their growth is shaped by specific social and historical conditions and,in turn,influences many aspects of wider economic and social development.In China's modernization process,they have always played a vital role.The 2024 Central Economic Work Conference placed strong emphasis on vigorously developing county economies. 展开更多
关键词 county economies economic social developmentin regional economic structure high quality development economic development local growth social historical conditions vigorously developing county economies
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Standards lead the high-quality development of intelligent construction in China
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作者 Cheng Zhijun 《China Standardization》 2026年第1期49-49,共1页
To advance intelligent construction,standards must come first.The Ministry of Housing and Urban-Rural Development has issued the List for Replicable Experience and Practices for Developing Intelligent Construction fou... To advance intelligent construction,standards must come first.The Ministry of Housing and Urban-Rural Development has issued the List for Replicable Experience and Practices for Developing Intelligent Construction four times successively and the Technical Guidelines for Intelligent Construction(Trial). 展开更多
关键词 STANDARDS technical guidelines high quality development Ministry Housing Urban Rural development intelligent constructionstandards replicable experience intelligent construction
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Health-related physical fitness in children and adolescents and the United Nations Sustainable Development Goals:Signals of convergence
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作者 Diego Augusto Santos Silva Mark S.Tremblay 《Journal of Sport and Health Science》 2026年第3期6-12,共7页
1.Background The United Nations(UN)2030 Agenda for Sustainable Development,adopted in 2015,established the Sustainable Development Goals(SDGs)as a comprehensive framework to address global challenges through interconn... 1.Background The United Nations(UN)2030 Agenda for Sustainable Development,adopted in 2015,established the Sustainable Development Goals(SDGs)as a comprehensive framework to address global challenges through interconnected social,economic,and environmental targets. 展开更多
关键词 sustainable development goals sdgs sustainable developmentadopted AGENDA children adolescents address global challenges united nations sustainable development goals
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Research on the Active and Passive Motion Characteristics of Bioinspired Soft Actuators
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作者 Qi Shen Jinzhu Zhang +2 位作者 Xiaoyan Xiong Hongjie Du Shiyu Li 《Journal of Bionic Engineering》 2026年第1期139-158,共20页
The soft actuator is characterized by high safety,flexibility,and adaptability.It is capable of both active and passive defor-mations.This paper presents a discrete degree of freedom(DOF)method for soft actuators to r... The soft actuator is characterized by high safety,flexibility,and adaptability.It is capable of both active and passive defor-mations.This paper presents a discrete degree of freedom(DOF)method for soft actuators to reveal DOF characteristics.The method draws on the superposition mechanism of the deformation characteristics of the sarcomere in the skeletal muscles of living organisms.Firstly,the multi-DOF deformation characteristics of the soft actuator are discretized into superimposed combinations of single-DOF micro-units.Then,the soft actuator was determined to contain deformation characteristics such as extension-contraction,bending,and twisting.Eighteen types of micro-units with basic deforma-tion characteristics were obtained depending on the axis and orientation.Further,the mapping relationship between the combination of micro-units and the motion characteristics of the soft actuator based on the GF set theory was established.Finally,an active-passive DOF co-structured soft actuator(APCSA)was developed.The graphical approach analyzes the experimental results,and it can be concluded that active and passive DOFs can coexist in the composite deformation of the soft actuator. 展开更多
关键词 Soft actuator Active and passive DOF characteristics Active and passive motion characteristics Micro-units G_(F)Set
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Rolling Out a Technocentric Rural Development Blueprint
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作者 ZHONG YU 《China Today》 2026年第1期26-29,共4页
China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have alwa... China aims to build on its achievements of the past five years to accelerate rural revitalization during the 15th Five-Year Plan period.IN China,issues relating to agriculture,rural areas,and rural residents have always been a priority in national development.At its fourth plenary session held in October 2025,the 20th Central Committee of the Communist Party of China(CPC)once again emphasized the need to accelerate agricultural and rural modernization,and advance all-around rural revitalization over the next five years. 展开更多
关键词 technocentric rural areas agricultural modernization accelerate agricultural rural modernizationand rural development five year plan rural revitalization national development
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Intersection of mitochondrial dysfunction and myelination:An overlooked aspect in neurodevelopmental disorders
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作者 Ariel Nir Sade Gal Wiener Boaz Barak 《Neural Regeneration Research》 2026年第2期659-660,共2页
Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables th... Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs. 展开更多
关键词 neurodevelopmental disorders ndds rokach white matter developing brain MYELINATION neurodevelopmental processes mitochondrial dysfunction white matter wm known developing braina
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