间歇生产过程具有弹性大、灵活等特点,其市场适应性较强。化工生产中间歇生产过程占相当比例,文章就间歇生产工艺的模拟与优化进行介绍,利用Aspen Batch Process Developer模拟间歇工艺过程,可以快速地得到工艺流程的物料衡算、热量衡...间歇生产过程具有弹性大、灵活等特点,其市场适应性较强。化工生产中间歇生产过程占相当比例,文章就间歇生产工艺的模拟与优化进行介绍,利用Aspen Batch Process Developer模拟间歇工艺过程,可以快速地得到工艺流程的物料衡算、热量衡算、操作时间、公用工程和成本估算等结果。同时,还可以对模拟结果进行分析,找出制约生产工艺的瓶颈,并对生产周期、生产规模、生产设备等进行优化,提高工艺设计效率,降低生产成本。展开更多
Machine Translation are increasingly welcomed and used during recent years with the commonly application of Internet and the acceleration of the integration of world economy. To know about the history and development ...Machine Translation are increasingly welcomed and used during recent years with the commonly application of Internet and the acceleration of the integration of world economy. To know about the history and development process of Machine Translation during 1930s-1970 s could help researchers gain new insights through restudying old material.展开更多
This paper reviewed the trend and development of semi-solid metal technique. The processes and mechanisms for producing slurry of SSM and its industrial applications have been summarized and discussed. Discussions on ...This paper reviewed the trend and development of semi-solid metal technique. The processes and mechanisms for producing slurry of SSM and its industrial applications have been summarized and discussed. Discussions on the basic rheological theory are presented for more applications. Further consideration of the development and application of SSM technique is also proposed.展开更多
Task decomposition is a kind of powerful technique increasingly being used within industry as a pathway for achieving product's developing success. In this paper, topology's concept in modern mathematics is us...Task decomposition is a kind of powerful technique increasingly being used within industry as a pathway for achieving product's developing success. In this paper, topology's concept in modern mathematics is used for task decomposition technique's deduction in product developing process. It puts fonvard the views of resolvability, measurability and connectivity of tasks and their practi-cal principles. Combined with an example of developing the typical mechanical product, it ex-plains the implementing method of task decomposition in Concurrent Engineering (CE).展开更多
he design verification steps that take place in today’s automotive industry, which constitute the values of each successive or simultaneous phase in the new product development process, create a complex structure wit...he design verification steps that take place in today’s automotive industry, which constitute the values of each successive or simultaneous phase in the new product development process, create a complex structure with the inclusion of each new technology and discipline. Therefore, step by step, each design verification phase definition in the flow contains important phase transition measurements or approval tolerances that ensure the simplicity and continuity of vehicle development processes. In addition, classification of design verification stages within the framework of this study or evaluation in two classes (static and dynamic) is a new approach, but it is a synthesis with the analysis of the new product development process. The vehicle’s basic structure, which constitutes the ergonomic and functional requirements of the vehicle in a static environment, takes into account the dynamic environment variables with crash or accident tests. Increasing new technology adaptations in the automotive industry have changed the new product development process that performs this function structurally and created the concept of design verification under consecutive or simultaneous process simplicity. From the autonomous driving to the use of alternative energy, possible accident scenarios and design verification phase transitions in the integration of parts and systems of the newly developed vehicle create a new structure that models and directs the lean product development process especially in the automotive industry in the coming days. In the lean product development process that takes place in the automotive industry, the design verification transition steps or the approval-control analysis of the development stages, which form a new and effective approach, are re-modeling the entire flow. Therefore, successful execution of design verification steps used in the control of new interdisciplinary product development phase transitions provides value creation.?Within the scope of this study, the effectiveness of the static and dynamic design verification steps, which are carried out in 5 global automotive companies included in the research, which constitute the stage transitions of the new product development process, has been measured. Apart from the design verification transition stages, the process variables that differ among the automotive companies involved in the research are excluded from the scope of this study. In other words, in field researches in the automotive industry, new vehicle design steps or basic engineering steps in the new product development process steps, while creating independent fixed variables, interdisciplinary collaborations, static and dynamic design verification transition stages they perform, or their sequence in the basic flow, is accepted as a dependent variable. Therefore, in the study, the positive effect of the automotive companies that included the static and dynamic design verification phase transition approvals in the lean product development process was investigated. Under the comparative analysis structure of the research, the effect of automotive companies, which accept international vehicle specifications as static design verification input, on market performance has been examined in depth. The detailed depth in the comparison analysis conducted under the second field studies of the study is due to the prediction of dynamic design verification stages to provide a high impact on the market performance, according to the static verification analysis. The new product development stages of the dependent variables were fixed and the flow-oriented?“effect”?of the independent variables in the basic process influenced by the design verification activities was analyzed under the new automotive industry company comparisons. In addition, the impact of the automotive design activities that make up the comparison analysis of the research on the scope of the lean product development stage and its effect on the basic process flow has been demonstrated competition-oriented. Therefore, sub-variables, options, criteria, results, which form a defined comparison problem, create basic test values that affect the problem.展开更多
In the present article we review behavioral and neurophysiological studies on face processing in adults and in early development. From the existing empirical and theoretical literature we derive three aspects that dis...In the present article we review behavioral and neurophysiological studies on face processing in adults and in early development. From the existing empirical and theoretical literature we derive three aspects that distinguish face processing from the processing of other visual object categories. Each of these aspects is discussed from a developmental perspective. First, faces are recognized and represented at the individual level rather than at the basic level. Second, humans typically acquire extensive expertise in individuating faces from early on in development. And third, more than other objects, faces are processed holistically. There is a quantitative difference in the amount of visual experience for faces and other object categories in that the amount of expertise typically acquired for faces is greater than that for other object categories. In addition, we discuss possible qualitative differences in experience for faces and objects. For instance, there is evidence for a sensitive period in infancy for building up a holistic face representation and for perceptual narrowing for faces of one＇s own species and race. We conclude our literature review with questions for future research, for instance, regarding the exact relationship between behavioral and neuronal markers of face processing across development.展开更多
This article presents a multiscale simulation approach starting at the molecular level for the adsorption process development. A grand canonical Monte Carlo method is used for the prediction of adsorption isotherms of...This article presents a multiscale simulation approach starting at the molecular level for the adsorption process development. A grand canonical Monte Carlo method is used for the prediction of adsorption isotherms of methanol on an activated carbon at the molecular level. The adsorption isotherms obtained in the linear region （or adsorption constant） are exploited as a model parameter required for the adsorption process simulation. The adsorption process model described by a set of partial differential equations （PDEs） is solved by using the conservation element and solution element method, which produces a fast and an accurate numerical solution to PDEs. The simulation results obtained from the adsorption constant estimated at the molecular level are in good agreement with the experimental results of the pulse response. The systematical multiscale simulation approach addressed in this study may be useful to accelerate the adsorption process development by reducing the number of experiments.展开更多
China＇s reform and opening-up policy has brought the country a great development opportunity. The high-speed growth of the economy not only led China to a period of industrialization, urbanization, informatization an...China＇s reform and opening-up policy has brought the country a great development opportunity. The high-speed growth of the economy not only led China to a period of industrialization, urbanization, informatization and agricultural modernization, but also exacerbated the situation of the urban–rural dual structure. Based on the review of current studies, we first used the analytic hierarchy process（AHP） method to evaluate the urban–rural development and transformation level by population transformation index, land transformation index, industrial transformation index and social transformation index between 1996 and 2012 around the Bohai Rim Region. Then, based on the results of each index, we used the exploratory spatial data analysis（ESDA） method to investigate the spatial autocorrelation of the change in the urban–rural development transformation index during the 16-year period using Global Moran＇s I index and Local Moran＇s I index. Finally, we investigated the mechanism of change of the urban–rural development transformation index at county level, summarizing five main factors：（1） the radiation from the surrounding big cities,（2） the acceleration of the urbanization process,（3） the upgrading of the industrial structure,（4） the publishing and implementation of a macro development strategy and regional policy, and（5） natural factors such as topology.展开更多
Today the cycle time of the product develop is requ ir ed to be shortened. At the same time the requirement of the customers becomes mo re and more diverse and complex. The capability of the develop unit is limited b ...Today the cycle time of the product develop is requ ir ed to be shortened. At the same time the requirement of the customers becomes mo re and more diverse and complex. The capability of the develop unit is limited b ecause of the existence of heterogeneous systems and distributed environments. I n this paper, we bring forward a new approach to solve the problem in product de velopment process. We also settle part key technologies in it. A great deal of information from all kinds of sources in the distributed develop ment process is interweaved. The solution to organize the workflow and manage th e information in the process is called for anxiously. We use a new approach that is asynchronous and synchronous coupling product development approach based on the network. The approach extends the develop process from the time axis. Then t he activities in the process are organized from the asynchronous and synchronous aspects. The state of every activity projects at the ASN (active semantic netwo rk). The ASN includes decision system, intelligent agent, user interface and net work. The ASN decides the types and states of the activities and deals with the couple relationship among them. The knowledge stored in ASN is open to all users through the relative interfaces. Every specialist keeps contact with their user s relying on collaborative platform implements CSCW (computer support collaborat ive work) that integrated product/process design and development. The lack of gl obal communication in product development process can be prevented in the most d egree. The key technologies that exist in the asynchronous and synchronous coupling pro duct develop approach include: integrated development structure, orderly organiz ation of information, transparent management of process, agile transfer of infor mation and rapid prototype. The development process can be completed quickly by these technologies. The technologies involve wide content. In this paper, we dis cuss some key technologies. We validate the approach by the projectrapid response manufacturing a pplication in the distributed environment. The expensive device, high technology and low using lead to RE (Rapid engineering) and RP (Rapid prototype) service a pplication by the network. RE and RP develop rapidly due to the accelerated prod uct development process. RE and RP application service platform is built in the project.展开更多
Product development process management plays an important role in concurrent engineering (CE). The integration platform is a useful tool for effectively supporting the software development and integration. Based on th...Product development process management plays an important role in concurrent engineering (CE). The integration platform is a useful tool for effectively supporting the software development and integration. Based on the analysis of practical requirements for product development process management for CE, a CORBA-based integration platform of product development process management (IP-PDPM) is designed and developed. The design principles for IP-PDPM are described. The system architecture and functions of the platform are given, the key technologies for the implementation of IP-PDPM are presented, the application integration mechanism and its implementation techniques are also detailed.展开更多
The IEC 61131-3 standard defines a model and a set of programming languages for the development of industrial automation software. It is widely accepted by industry and most of the commercial tool vendors advertise co...The IEC 61131-3 standard defines a model and a set of programming languages for the development of industrial automation software. It is widely accepted by industry and most of the commercial tool vendors advertise compliance with it. On the other side, Model Driven Development (MDD) has been proved as a quite successful paradigm in general-purpose computing. This was the motivation for exploiting the benefits of MDD in the industrial automation domain. With the emerging IEC 61131 specification that defines an object-oriented (OO) extension to the function block model, there will be a push to the industry to better exploit the benefits of MDD in automation systems development. This work discusses possible alternatives to integrate the current but also the emerging specification of IEC 61131 in the model driven development process of automation systems. IEC 61499, UML and SysML are considered as possible alternatives to allow the developer to work in higher layers of abstraction than the one supported by IEC 61131 and to more effectively move from requirement specifications into the implementation model of the system.展开更多
The development and delivery of high quality therapeutic products necessitates the need for highthrough-put (HTP) process development tools. Traditionally, these works requires a combination of shake flask and small-s...The development and delivery of high quality therapeutic products necessitates the need for highthrough-put (HTP) process development tools. Traditionally, these works requires a combination of shake flask and small-scale stirred tank bioreactor (STR) which are labor and resource intensive and time-consuming. Here we demonstrate a strategy for rapid and robust cell culture process development by evaluating and implementing the use of a new HTP disposable micro bioreactor (MBR) called AMBRTM system (Advanced Microscale Bioreactor) that has the capabilities for automated sampling, feed addition, pH, dissolved oxygen (DO), gassing and agitation controls. In these studies the performance of two monoclonal antibody (MAb) producing cell lines (MAb1 and MAb2) was evaluated both in the AMBR system and 3-L STR. We demonstrated that cell culture performance (growth and viability, production titer and product quality) were similar in both vessel systems. Furthermore, process control and feed optimization were demonstrated in an additional cell line (MAb3) in the disposable MBR and its performance confirmed at STR scale. The results indicate that the AMBR system can be used to streamline the process development effort and facilitate a rapid and robust cell culture process development effort for MAb programs in a HTP manner.展开更多
A methodology is presented to identify environmental impact minimization alternatives for reaction processes and assess their environmental performance. The potential environmental impact (PEI) scheme can be used to v...A methodology is presented to identify environmental impact minimization alternatives for reaction processes and assess their environmental performance. The potential environmental impact (PEI) scheme can be used to visibly display the transformation relationships among different types of PEI, identify the sources of environmental impacts, and propose alternatives for eliminating or minimizing the impacts. To evaluate the environmental performance of the alternatives effectively, some new indices, such as PEI input rate of non-products, PEI output rate of non-products per profit and the PEI conversion efficiency are proposed. Finally, the application of the methodology is illustrated using an industrial case study.展开更多
DSS have high strength,high corrosion resistance and good welding properties.Comparing with the same corrosion resistance level austenitic stainless steel,DSS decrease largely Ni content and realize the thinning of th...DSS have high strength,high corrosion resistance and good welding properties.Comparing with the same corrosion resistance level austenitic stainless steel,DSS decrease largely Ni content and realize the thinning of thickness design to perfectly optimize properties and decrease costs.Now DSS have been widely used in many fields such as petroleum,chemical industry,paper production,shipbuilding,nuclear power,seawater desalting,vacuum salt production and architecture.Tisco have began the process development and product application research of DSS products from last century and gradually solved a lot of technical problems such as AOD nitrogen alloying control of various content DSS,high temperature deformation mechanism of thermal process,large deformation hot rolling process of coils,the effect of bad phase precipitated during hot treatment process on properties and high efficiency pickling of high Cr/Mo content DSS plates.The various alloy content DSS plates and wide cold rolling coils(3Re60,S32101,S32304,S31803,S32205,S32750 and SUS329J4L)were successfully developed and used in national important constructions,key industries and abroad projects.展开更多
In this paper,the development process of the construction of soil environmental quality standards in China is reviewed,and the construction situation of soil environmental quality standards in typical developed countr...In this paper,the development process of the construction of soil environmental quality standards in China is reviewed,and the construction situation of soil environmental quality standards in typical developed countries is introduced.According to characteristics of soil environment and practice of soil environment management in China,the relevant suggestions are discussed,thereby further perfecting construction work of soil environmental quality standards in China.展开更多
In this work, we used a linear CCD to detect the whole physical developing process of silver diffusion transfer reversal process in photographic chemistry. The influence of the ingredient of the working solution was s...In this work, we used a linear CCD to detect the whole physical developing process of silver diffusion transfer reversal process in photographic chemistry. The influence of the ingredient of the working solution was studied.展开更多
Hainan's betel nut processing industry continues to develop,and the yield has reached 231000 t. There are some problems in betel nut industry such as unreasonable initial processing layout,processing capacity surp...Hainan's betel nut processing industry continues to develop,and the yield has reached 231000 t. There are some problems in betel nut industry such as unreasonable initial processing layout,processing capacity surplus,and deep processing industry lag. It is suggested that we should guide the initial processing layout of betel nut according to local conditions,and carry out overall deep processing planning of betel nut; support betel nut deep processing plant in the main producing areas,establish betel nut initial processing and deep processing serial production line,and develop new betel nut product; build betel nut production,processing,transport and marketing information database and market information early warning mechanism,and improve betel nut processing information service platform to timely provide information services and continuously develop betel nut industry.展开更多
A process of ＂Methanol or Dimethylether to Olefins＂ developed by Dalian Institute of Chemical Physics （DICP）, designated as the DMTO process, has attained great success in industrial scaling up testing. DICP, by c...A process of ＂Methanol or Dimethylether to Olefins＂ developed by Dalian Institute of Chemical Physics （DICP）, designated as the DMTO process, has attained great success in industrial scaling up testing. DICP, by collaborating with the Xinxing Coal Chemical Co., Ltd. of Shaanxi Province and the Luoyang Petrochemical Engineering Co. of the SINOPEC Group, operated successfully a 50t（methanol）/d unit for the conversion of methanol to lower olefins, with a methanol conversion of close to 100%, and a selectivity to lower olefins（ethylene, propylene and butylenes） of higher than 90%. On 23rd August, the industrial test project has passed a state appraisal. The experts of the Appraisal Group, headed by Prof. YUAN Qingtang, academician of Chinese Academy of Engineering, drew the conclusions that the DMTO process, by utilizing a proprietary SAPO-34 catalyst system and a recycling fluidized bed reaction system for the production of lower olefins from methanol, is the first unit in the world having a capacity of producing nearly ten thousand tons lower olefins per year. The technological level of the industrial test is at a leading position internationally. This accomplishment will provide a sound base for the subsequent commercialization of the DMTO process.展开更多
The objective of this paper is to create a process view of the development of intermodal transport solution from the basic idea to implementation. Special case of dedicated solutions based on large shippers’ volumes ...The objective of this paper is to create a process view of the development of intermodal transport solution from the basic idea to implementation. Special case of dedicated solutions based on large shippers’ volumes is chosen, where the shippers engage in the development process of the new solutions. Research is conducted using a qualitative approach: multiple case studies. Empirical data has been obtained through in-depth semi-structured interviews with relevant respondents involved in the development projects. Shippers’ perspective on the development process is studied. Development process can be described through a generic four-stage process: Initiation, Planning, Implementation, and Further Development. Different actors and different resources are required at the different stages. The complex process of establishing new intermodal solutions has lacked attention in the intermodal research. Understanding and improving the development process of new intermodal solutions is considered to have an important effect on the viability of intermodal transport and can help to understand the barriers that prevent companies from switching to intermodal. Development process of new dedicated intermodal solutions is a gradual process of building up the transport solution in a continuous interaction between shippers and transport service providers. Research has focused on the shipper perspective on inter-modal transport, showing that switching to an intermodal transport is not simply a mode choice issue, but involves a transition process that takes time, demands resources, cooperation/coordination between multiple parties, may require changes in the supply chain beyond the transport link, involves multiple actors, and involves an industry that is itself in a process of change.展开更多
1 Introduction The 21st century is coming and the world iron and steel making technology is facing an important technical evolution at this century turnover,which is reflected in two aspects:①Rapid development of tra...1 Introduction The 21st century is coming and the world iron and steel making technology is facing an important technical evolution at this century turnover,which is reflected in two aspects:①Rapid development of traditional iron&steel making technology with continuous regeneration;②Three major frontier techniques of metallurgy(smelting reduction;near-net-shape continuous展开更多
文摘间歇生产过程具有弹性大、灵活等特点,其市场适应性较强。化工生产中间歇生产过程占相当比例,文章就间歇生产工艺的模拟与优化进行介绍,利用Aspen Batch Process Developer模拟间歇工艺过程,可以快速地得到工艺流程的物料衡算、热量衡算、操作时间、公用工程和成本估算等结果。同时,还可以对模拟结果进行分析,找出制约生产工艺的瓶颈,并对生产周期、生产规模、生产设备等进行优化,提高工艺设计效率,降低生产成本。
文摘Machine Translation are increasingly welcomed and used during recent years with the commonly application of Internet and the acceleration of the integration of world economy. To know about the history and development process of Machine Translation during 1930s-1970 s could help researchers gain new insights through restudying old material.
基金the National Natural Science foundation of China! (59995440)
文摘This paper reviewed the trend and development of semi-solid metal technique. The processes and mechanisms for producing slurry of SSM and its industrial applications have been summarized and discussed. Discussions on the basic rheological theory are presented for more applications. Further consideration of the development and application of SSM technique is also proposed.
基金the State High-Tech Developmets Plan of Cina(No.863-511-9930-007)
文摘Task decomposition is a kind of powerful technique increasingly being used within industry as a pathway for achieving product's developing success. In this paper, topology's concept in modern mathematics is used for task decomposition technique's deduction in product developing process. It puts fonvard the views of resolvability, measurability and connectivity of tasks and their practi-cal principles. Combined with an example of developing the typical mechanical product, it ex-plains the implementing method of task decomposition in Concurrent Engineering (CE).
文摘he design verification steps that take place in today’s automotive industry, which constitute the values of each successive or simultaneous phase in the new product development process, create a complex structure with the inclusion of each new technology and discipline. Therefore, step by step, each design verification phase definition in the flow contains important phase transition measurements or approval tolerances that ensure the simplicity and continuity of vehicle development processes. In addition, classification of design verification stages within the framework of this study or evaluation in two classes (static and dynamic) is a new approach, but it is a synthesis with the analysis of the new product development process. The vehicle’s basic structure, which constitutes the ergonomic and functional requirements of the vehicle in a static environment, takes into account the dynamic environment variables with crash or accident tests. Increasing new technology adaptations in the automotive industry have changed the new product development process that performs this function structurally and created the concept of design verification under consecutive or simultaneous process simplicity. From the autonomous driving to the use of alternative energy, possible accident scenarios and design verification phase transitions in the integration of parts and systems of the newly developed vehicle create a new structure that models and directs the lean product development process especially in the automotive industry in the coming days. In the lean product development process that takes place in the automotive industry, the design verification transition steps or the approval-control analysis of the development stages, which form a new and effective approach, are re-modeling the entire flow. Therefore, successful execution of design verification steps used in the control of new interdisciplinary product development phase transitions provides value creation.?Within the scope of this study, the effectiveness of the static and dynamic design verification steps, which are carried out in 5 global automotive companies included in the research, which constitute the stage transitions of the new product development process, has been measured. Apart from the design verification transition stages, the process variables that differ among the automotive companies involved in the research are excluded from the scope of this study. In other words, in field researches in the automotive industry, new vehicle design steps or basic engineering steps in the new product development process steps, while creating independent fixed variables, interdisciplinary collaborations, static and dynamic design verification transition stages they perform, or their sequence in the basic flow, is accepted as a dependent variable. Therefore, in the study, the positive effect of the automotive companies that included the static and dynamic design verification phase transition approvals in the lean product development process was investigated. Under the comparative analysis structure of the research, the effect of automotive companies, which accept international vehicle specifications as static design verification input, on market performance has been examined in depth. The detailed depth in the comparison analysis conducted under the second field studies of the study is due to the prediction of dynamic design verification stages to provide a high impact on the market performance, according to the static verification analysis. The new product development stages of the dependent variables were fixed and the flow-oriented?“effect”?of the independent variables in the basic process influenced by the design verification activities was analyzed under the new automotive industry company comparisons. In addition, the impact of the automotive design activities that make up the comparison analysis of the research on the scope of the lean product development stage and its effect on the basic process flow has been demonstrated competition-oriented. Therefore, sub-variables, options, criteria, results, which form a defined comparison problem, create basic test values that affect the problem.
文摘In the present article we review behavioral and neurophysiological studies on face processing in adults and in early development. From the existing empirical and theoretical literature we derive three aspects that distinguish face processing from the processing of other visual object categories. Each of these aspects is discussed from a developmental perspective. First, faces are recognized and represented at the individual level rather than at the basic level. Second, humans typically acquire extensive expertise in individuating faces from early on in development. And third, more than other objects, faces are processed holistically. There is a quantitative difference in the amount of visual experience for faces and other object categories in that the amount of expertise typically acquired for faces is greater than that for other object categories. In addition, we discuss possible qualitative differences in experience for faces and objects. For instance, there is evidence for a sensitive period in infancy for building up a holistic face representation and for perceptual narrowing for faces of one＇s own species and race. We conclude our literature review with questions for future research, for instance, regarding the exact relationship between behavioral and neuronal markers of face processing across development.
基金the Basic Research Program of the Korea Science & Engineering Foundation (KoSEF, No. R01-2006-000-10786-0).
文摘This article presents a multiscale simulation approach starting at the molecular level for the adsorption process development. A grand canonical Monte Carlo method is used for the prediction of adsorption isotherms of methanol on an activated carbon at the molecular level. The adsorption isotherms obtained in the linear region （or adsorption constant） are exploited as a model parameter required for the adsorption process simulation. The adsorption process model described by a set of partial differential equations （PDEs） is solved by using the conservation element and solution element method, which produces a fast and an accurate numerical solution to PDEs. The simulation results obtained from the adsorption constant estimated at the molecular level are in good agreement with the experimental results of the pulse response. The systematical multiscale simulation approach addressed in this study may be useful to accelerate the adsorption process development by reducing the number of experiments.
基金National Natural Science Foundation of China,No.41130748No.41471143
文摘China＇s reform and opening-up policy has brought the country a great development opportunity. The high-speed growth of the economy not only led China to a period of industrialization, urbanization, informatization and agricultural modernization, but also exacerbated the situation of the urban–rural dual structure. Based on the review of current studies, we first used the analytic hierarchy process（AHP） method to evaluate the urban–rural development and transformation level by population transformation index, land transformation index, industrial transformation index and social transformation index between 1996 and 2012 around the Bohai Rim Region. Then, based on the results of each index, we used the exploratory spatial data analysis（ESDA） method to investigate the spatial autocorrelation of the change in the urban–rural development transformation index during the 16-year period using Global Moran＇s I index and Local Moran＇s I index. Finally, we investigated the mechanism of change of the urban–rural development transformation index at county level, summarizing five main factors：（1） the radiation from the surrounding big cities,（2） the acceleration of the urbanization process,（3） the upgrading of the industrial structure,（4） the publishing and implementation of a macro development strategy and regional policy, and（5） natural factors such as topology.
文摘Today the cycle time of the product develop is requ ir ed to be shortened. At the same time the requirement of the customers becomes mo re and more diverse and complex. The capability of the develop unit is limited b ecause of the existence of heterogeneous systems and distributed environments. I n this paper, we bring forward a new approach to solve the problem in product de velopment process. We also settle part key technologies in it. A great deal of information from all kinds of sources in the distributed develop ment process is interweaved. The solution to organize the workflow and manage th e information in the process is called for anxiously. We use a new approach that is asynchronous and synchronous coupling product development approach based on the network. The approach extends the develop process from the time axis. Then t he activities in the process are organized from the asynchronous and synchronous aspects. The state of every activity projects at the ASN (active semantic netwo rk). The ASN includes decision system, intelligent agent, user interface and net work. The ASN decides the types and states of the activities and deals with the couple relationship among them. The knowledge stored in ASN is open to all users through the relative interfaces. Every specialist keeps contact with their user s relying on collaborative platform implements CSCW (computer support collaborat ive work) that integrated product/process design and development. The lack of gl obal communication in product development process can be prevented in the most d egree. The key technologies that exist in the asynchronous and synchronous coupling pro duct develop approach include: integrated development structure, orderly organiz ation of information, transparent management of process, agile transfer of infor mation and rapid prototype. The development process can be completed quickly by these technologies. The technologies involve wide content. In this paper, we dis cuss some key technologies. We validate the approach by the projectrapid response manufacturing a pplication in the distributed environment. The expensive device, high technology and low using lead to RE (Rapid engineering) and RP (Rapid prototype) service a pplication by the network. RE and RP develop rapidly due to the accelerated prod uct development process. RE and RP application service platform is built in the project.
文摘Product development process management plays an important role in concurrent engineering (CE). The integration platform is a useful tool for effectively supporting the software development and integration. Based on the analysis of practical requirements for product development process management for CE, a CORBA-based integration platform of product development process management (IP-PDPM) is designed and developed. The design principles for IP-PDPM are described. The system architecture and functions of the platform are given, the key technologies for the implementation of IP-PDPM are presented, the application integration mechanism and its implementation techniques are also detailed.
文摘The IEC 61131-3 standard defines a model and a set of programming languages for the development of industrial automation software. It is widely accepted by industry and most of the commercial tool vendors advertise compliance with it. On the other side, Model Driven Development (MDD) has been proved as a quite successful paradigm in general-purpose computing. This was the motivation for exploiting the benefits of MDD in the industrial automation domain. With the emerging IEC 61131 specification that defines an object-oriented (OO) extension to the function block model, there will be a push to the industry to better exploit the benefits of MDD in automation systems development. This work discusses possible alternatives to integrate the current but also the emerging specification of IEC 61131 in the model driven development process of automation systems. IEC 61499, UML and SysML are considered as possible alternatives to allow the developer to work in higher layers of abstraction than the one supported by IEC 61131 and to more effectively move from requirement specifications into the implementation model of the system.
文摘The development and delivery of high quality therapeutic products necessitates the need for highthrough-put (HTP) process development tools. Traditionally, these works requires a combination of shake flask and small-scale stirred tank bioreactor (STR) which are labor and resource intensive and time-consuming. Here we demonstrate a strategy for rapid and robust cell culture process development by evaluating and implementing the use of a new HTP disposable micro bioreactor (MBR) called AMBRTM system (Advanced Microscale Bioreactor) that has the capabilities for automated sampling, feed addition, pH, dissolved oxygen (DO), gassing and agitation controls. In these studies the performance of two monoclonal antibody (MAb) producing cell lines (MAb1 and MAb2) was evaluated both in the AMBR system and 3-L STR. We demonstrated that cell culture performance (growth and viability, production titer and product quality) were similar in both vessel systems. Furthermore, process control and feed optimization were demonstrated in an additional cell line (MAb3) in the disposable MBR and its performance confirmed at STR scale. The results indicate that the AMBR system can be used to streamline the process development effort and facilitate a rapid and robust cell culture process development effort for MAb programs in a HTP manner.
基金National Natural Science Foundation of China(No.20176045)Major State Basic Research Development Program(No.G20000263)
文摘A methodology is presented to identify environmental impact minimization alternatives for reaction processes and assess their environmental performance. The potential environmental impact (PEI) scheme can be used to visibly display the transformation relationships among different types of PEI, identify the sources of environmental impacts, and propose alternatives for eliminating or minimizing the impacts. To evaluate the environmental performance of the alternatives effectively, some new indices, such as PEI input rate of non-products, PEI output rate of non-products per profit and the PEI conversion efficiency are proposed. Finally, the application of the methodology is illustrated using an industrial case study.
文摘DSS have high strength,high corrosion resistance and good welding properties.Comparing with the same corrosion resistance level austenitic stainless steel,DSS decrease largely Ni content and realize the thinning of thickness design to perfectly optimize properties and decrease costs.Now DSS have been widely used in many fields such as petroleum,chemical industry,paper production,shipbuilding,nuclear power,seawater desalting,vacuum salt production and architecture.Tisco have began the process development and product application research of DSS products from last century and gradually solved a lot of technical problems such as AOD nitrogen alloying control of various content DSS,high temperature deformation mechanism of thermal process,large deformation hot rolling process of coils,the effect of bad phase precipitated during hot treatment process on properties and high efficiency pickling of high Cr/Mo content DSS plates.The various alloy content DSS plates and wide cold rolling coils(3Re60,S32101,S32304,S31803,S32205,S32750 and SUS329J4L)were successfully developed and used in national important constructions,key industries and abroad projects.
基金Supported by Preparation Project of Science Popularization Materials for Publicity and Education of Soil Environmental Protection,Ministry of Environmental Protection(H201606)
文摘In this paper,the development process of the construction of soil environmental quality standards in China is reviewed,and the construction situation of soil environmental quality standards in typical developed countries is introduced.According to characteristics of soil environment and practice of soil environment management in China,the relevant suggestions are discussed,thereby further perfecting construction work of soil environmental quality standards in China.
文摘In this work, we used a linear CCD to detect the whole physical developing process of silver diffusion transfer reversal process in photographic chemistry. The influence of the ingredient of the working solution was studied.
基金Supported by Special Project for Research,Development,Demonstration and Extension of Applied Technology in Hainan Province(ZDXM2014101)
文摘Hainan's betel nut processing industry continues to develop,and the yield has reached 231000 t. There are some problems in betel nut industry such as unreasonable initial processing layout,processing capacity surplus,and deep processing industry lag. It is suggested that we should guide the initial processing layout of betel nut according to local conditions,and carry out overall deep processing planning of betel nut; support betel nut deep processing plant in the main producing areas,establish betel nut initial processing and deep processing serial production line,and develop new betel nut product; build betel nut production,processing,transport and marketing information database and market information early warning mechanism,and improve betel nut processing information service platform to timely provide information services and continuously develop betel nut industry.
文摘A process of ＂Methanol or Dimethylether to Olefins＂ developed by Dalian Institute of Chemical Physics （DICP）, designated as the DMTO process, has attained great success in industrial scaling up testing. DICP, by collaborating with the Xinxing Coal Chemical Co., Ltd. of Shaanxi Province and the Luoyang Petrochemical Engineering Co. of the SINOPEC Group, operated successfully a 50t（methanol）/d unit for the conversion of methanol to lower olefins, with a methanol conversion of close to 100%, and a selectivity to lower olefins（ethylene, propylene and butylenes） of higher than 90%. On 23rd August, the industrial test project has passed a state appraisal. The experts of the Appraisal Group, headed by Prof. YUAN Qingtang, academician of Chinese Academy of Engineering, drew the conclusions that the DMTO process, by utilizing a proprietary SAPO-34 catalyst system and a recycling fluidized bed reaction system for the production of lower olefins from methanol, is the first unit in the world having a capacity of producing nearly ten thousand tons lower olefins per year. The technological level of the industrial test is at a leading position internationally. This accomplishment will provide a sound base for the subsequent commercialization of the DMTO process.
文摘The objective of this paper is to create a process view of the development of intermodal transport solution from the basic idea to implementation. Special case of dedicated solutions based on large shippers’ volumes is chosen, where the shippers engage in the development process of the new solutions. Research is conducted using a qualitative approach: multiple case studies. Empirical data has been obtained through in-depth semi-structured interviews with relevant respondents involved in the development projects. Shippers’ perspective on the development process is studied. Development process can be described through a generic four-stage process: Initiation, Planning, Implementation, and Further Development. Different actors and different resources are required at the different stages. The complex process of establishing new intermodal solutions has lacked attention in the intermodal research. Understanding and improving the development process of new intermodal solutions is considered to have an important effect on the viability of intermodal transport and can help to understand the barriers that prevent companies from switching to intermodal. Development process of new dedicated intermodal solutions is a gradual process of building up the transport solution in a continuous interaction between shippers and transport service providers. Research has focused on the shipper perspective on inter-modal transport, showing that switching to an intermodal transport is not simply a mode choice issue, but involves a transition process that takes time, demands resources, cooperation/coordination between multiple parties, may require changes in the supply chain beyond the transport link, involves multiple actors, and involves an industry that is itself in a process of change.
文摘1 Introduction The 21st century is coming and the world iron and steel making technology is facing an important technical evolution at this century turnover,which is reflected in two aspects:①Rapid development of traditional iron&steel making technology with continuous regeneration;②Three major frontier techniques of metallurgy(smelting reduction;near-net-shape continuous
