Objective To evaluate the clinical value of siltuximab in the treatment of Castleman disease based on multicriteria decision analysis(MCDA)and evidence and value:Impact on decision making(EVIDEM)framework.Methods The ...Objective To evaluate the clinical value of siltuximab in the treatment of Castleman disease based on multicriteria decision analysis(MCDA)and evidence and value:Impact on decision making(EVIDEM)framework.Methods The evidence matrix for quantitative analysis of MCDA was extracted through literature research,and the weight of each evaluation index was calculated by the maximum differentiation measure in conjoint analysis.Besides,the clinical value of siltuximab in the treatment of Castleman disease was analyzed quantitatively and qualitatively based on the results of expert questionnaire surveys.Results and Conclusion The clinical value score of siltuximab was 0.491,and the weight ratio of“therapeutic benefit”(15.39%),“drug effectiveness”(14.46%)and“drug safety”(11.43%)were the three largest.Among the indexes of“drug effectiveness”“drug safety”“patient reported outcome”“therapeutic benefit”and“non-medical cost”,siltuximab for Castleman disease was considered to be a more valuable treatment option than other first-line therapies.By qualitative analysis,57%experts believed that siltuximab was a better treatment option.The indexes that contribute the most to the overall clinical value of siltuximab are“therapeutic benefit”“drug effectiveness”and“quality of evidence”,while the indexes that have a negative impact on the clinical value of siltuximab is“drug treatment cost”.展开更多
Environmental problems are intensifying due to the rapid growth of the population,industry,and urban infrastructure.This expansion has resulted in increased air and water pollution,intensified urban heat island effect...Environmental problems are intensifying due to the rapid growth of the population,industry,and urban infrastructure.This expansion has resulted in increased air and water pollution,intensified urban heat island effects,and greater runoff from parks and other green spaces.Addressing these challenges requires prioritizing green infrastructure and other sustainable urban development strategies.This study introduces a novel Integrated Decision Support System that combines Pythagorean Fuzzy Sets with the Advanced Alternative Ranking Order Method allowing for Two-Step Normalization(AAROM-TN),enhanced by a dual weighting strategy.The weighting approach integrates the Criteria Importance Through Intercriteria Correlation(CRITIC)method with the Criteria Importance through Means and Standard Deviation(CIMAS)technique.The originality of the proposed framework lies in its ability to objectively quantify criteria importance using CRITIC,incorporate decision-makers’preferences through CIMAS,and capture the uncertainty and hesitation inherent in human judgment via Pythagorean Fuzzy Sets.A case study evaluating green infrastructure alternatives in metropolitan regions demonstrates the applicability and effectiveness of the framework.A sensitivity analysis is conducted to examine how variations in criteria weights affect the rankings and to evaluate the robustness of the results.Furthermore,a comparative analysis highlights the practical and financial implications of each alternative by assessing their respective strengths and weaknesses.展开更多
Weak measurement offers a powerful framework for probing nonclassical features of quantum mechanics,with anomalous weak values serving as operational signatures of contextuality.While the anomalous weak value verifica...Weak measurement offers a powerful framework for probing nonclassical features of quantum mechanics,with anomalous weak values serving as operational signatures of contextuality.While the anomalous weak value verification of quantum contextuality has been predominantly investigated in the single-photon regime and analyzed under approximation condition of infinitesimally small perturbation strength.This study releases the approximation condition and takes into account the impact of perturbation strength on the rigor of the verification.And the investigation on the verification of contextuality is extended to the multi-photon scenarios for observing the influence of the correlation between photons on the verification.Without the limitation of infinitesimally small probability of disturbance,anomalous weak values are identified as necessary for contextuality to emerge,thereby refining the criterion proposed by Pusey[Phys.Rev.Lett.113200401(2014)].In the multi-photon scenarios,the emergence of contextuality also depends strongly on both the photon number and the photon-number distribution state.In particular,contextuality is found to be maximized when the single-photon component dominates and the second-order correlation is lower.These results highlight the critical role of photon statistics in experimental tests of contextuality via anomalous weak values.展开更多
With the increasing complexity of industrial automation,planetary gearboxes play a vital role in largescale equipment transmission systems,directly impacting operational efficiency and safety.Traditional maintenance s...With the increasing complexity of industrial automation,planetary gearboxes play a vital role in largescale equipment transmission systems,directly impacting operational efficiency and safety.Traditional maintenance strategies often struggle to accurately predict the degradation process of equipment,leading to excessive maintenance costs or potential failure risks.However,existing prediction methods based on statistical models are difficult to adapt to nonlinear degradation processes.To address these challenges,this study proposes a novel condition-based maintenance framework for planetary gearboxes.A comprehensive full-lifecycle degradation experiment was conducted to collect raw vibration signals,which were then processed using a temporal convolutional network autoencoder with multi-scale perception capability to extract deep temporal degradation features,enabling the collaborative extraction of longperiod meshing frequencies and short-term impact features from the vibration signals.Kernel principal component analysis was employed to fuse and normalize these features,enhancing the characterization of degradation progression.A nonlinear Wiener process was used to model the degradation trajectory,with a threshold decay function introduced to dynamically adjust maintenance strategies,and model parameters optimized through maximum likelihood estimation.Meanwhile,the maintenance strategy was optimized to minimize costs per unit time,determining the optimal maintenance timing and preventive maintenance threshold.The comprehensive indicator of degradation trends extracted by this method reaches 0.756,which is 41.2%higher than that of traditional time-domain features;the dynamic threshold strategy reduces the maintenance cost per unit time to 55.56,which is 8.9%better than that of the static threshold optimization.Experimental results demonstrate significant reductions in maintenance costs while enhancing system reliability and safety.This study realizes the organic integration of deep learning and reliability theory in the maintenance of planetary gearboxes,provides an interpretable solution for the predictive maintenance of complex mechanical systems,and promotes the development of condition-based maintenance strategies for planetary gearboxes.展开更多
AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control stu...AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control study included participants who underwent routine complete blood count testing.Inflammation-related indices,including neutrophil-to-lymphocyte ratio,systemic immune-inflammation index(SII),and PIV,were derived and analyzed.Receiver operating characteristic curve(ROC)analysis was applied to assess the diagnostic performance of these indices in distinguishing patients with PDR,with sensitivity,specificity,area under ROC,and optimal threshold values calculated.In addition,binary logistic regression analysis was performed to evaluate the association between inflammatory indices and PDR stage.RESULTS:This study included 205 patients:60 with diabetes without retinopathy(mean age:61.81±10.76y),80 with PDR(mean age:61.63±10.03y)and 65 healthy controls(mean age:59.52±5.88y).The PDR group had significantly higher white blood cell(WBC,P<0.001),monocyte(MONO,P=0.009)and neutrophil(NEU)counts(P<0.001).SII and PIV had the highest sensitivity and area under ROC for predicting patients with PDR(0.822,0.846,respectively).The optimal cut-off values for discriminating patients with PDR were determined to be>527.12 and>299.08 for SII and PIV,respectively.The logistic regression analysis demonstrated that a decrease in lymphocyte(LYM)count and an increase in platelet count(PLT),glycated haemoglobin(HbA1c),SII,and PIV were all significantly associated with the development of high-risk PDR(all P<0.05).PIV was more stable than independent MONO,LYM,PLT and NEU levels in predicting both the diagnosis and stage of PDR.The optimal cut-off value for PIV to discriminate patients with high-risk PDR was found to be>345.87 area under ROC=0.871,with sensitivity of 0.827 and specificity of 0.812.CONCLUSION:PIV is a reliable,valuable,and inexpensive blood index that can be used for early detection and staging of PDR.PIV may therefore be essential to be used for the follow-up of diabetic patients.展开更多
In this paper,we study the nonlinear Riemann boundary value problem with square roots that is represented by a Cauchy-type integral with kernel density in variable exponent Lebesgue spaces.We discuss the odd-order zer...In this paper,we study the nonlinear Riemann boundary value problem with square roots that is represented by a Cauchy-type integral with kernel density in variable exponent Lebesgue spaces.We discuss the odd-order zero-points distribution of the solutions and separate the single valued analytic branch of the solutions with square roots,then convert the problem to a Riemann boundary value problem in variable exponent Lebesgue spaces and discuss the singularity of solutions at individual zeros belonging to curve.We consider two types of cases those where the coefficient is Hölder and those where it is piecewise Hölder.Then we solve the Hilbert boundary value problem with square roots in variable exponent Lebesgue spaces.By discussing the distribution of the odd-order zero-points for solutions and the method of symmetric extension,we convert the Hilbert problem to a Riemann boundary value problem.The equivalence of the transformation is discussed.Finally,we get the solvable conditions and the direct expressions of the solutions in variable exponent Lebesgue spaces.展开更多
The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation...The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation and evolution of Meizhou pomelo industry cluster in China,focusing on its role in restructuring rural socio-economic systems and integrating the whole value chains.Based on a case study employing qualitative methods such as in-depth interviews and participatory observation,the agricultural cluster evolution of Meizhou pomelo was categorized into three key phases of initial decentralization,self-organized scaling,and reorganized clustering.Geographical proximity and industrial agglomeration constitute the physical foundation,while vertical/horizontal linkages,technologic-al innovation,and policy support enhance competitiveness.Special mechanisms emerge through localized social networks,farmer co-operatives’activation,and cross-regional market expansion.The cluster’s impact is manifested in the shift from extensive to standard-ized and modernized production,diversified and flexible livelihood of farmers,and the integration of agriculture with industry and ser-vices.The development of the whole value chain based on agricultural cluster represents a critical pathway for achieving agricultural modernization,encompassing both internal and external value chain optimization.Through quality assurance systems,product diversi-fication strategies,operational efficiency improvements,and brand enhancement,these clusters amplify product value propositions and market competitiveness.This systemic approach facilitates supply-demand coordination,enables resource synergies,and optimizes eco-nomic returns across the horizontal and vertical value chain.This paper argues that agricultural clusters serve as strategic catalysts for sustainable rural development by reconstructing local production systems,fostering innovation ecosystems,and aligning agricultural modernization.It contributes to debates on rural vitalization by demonstrating how agricultural clustering can reconfigure rural areas as hubs of ecological modernization,rather than mere urban peripheries.展开更多
The Double Take column looks at a single topic from an African and Chinese perspective.This month,we discuss how to understand the growing emphasis on emotional returns among young people.Emotional value has emerged a...The Double Take column looks at a single topic from an African and Chinese perspective.This month,we discuss how to understand the growing emphasis on emotional returns among young people.Emotional value has emerged as a central force shaping youth decision-making across work,consumption,relationships and lifestyle choices.Unlike traditional economic rationality that prioritises income and material security,emotional value focuses on how choices make individuals feel and how they align with personal meaning.This shift is particularly evident in rapidly transforming societies such as China and Ghana,where economic restructuring,globalisation and social change have reshaped pathways to adulthood.展开更多
Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pP...Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such uncertainties.This study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and AND-operations.Some results related to these operations are also modified for pPyFHSS.Additionally,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and results.Lastly,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested system.The algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical models.Similarly,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison.展开更多
Ming-style furniture represents the pinnacle of Chinese traditional furniture,with the four-head official’s cap chair standing out as a representative category due to its classic form and cultural connotations.This p...Ming-style furniture represents the pinnacle of Chinese traditional furniture,with the four-head official’s cap chair standing out as a representative category due to its classic form and cultural connotations.This paper takes a specific rosewood four-head official’s cap chair inscribed by Wang Shixiang as the research subject,employing a tripartite approach of form analysis,material examination,and inscription interpretation.The chair strictly adheres to the classic form of Ming-style four-head official’s cap chairs,embodying the Ming Dynasty design philosophy of“the unity of function and aesthetics”.The scarcity and unique grain pattern of the golden-flecked rosewood(Zitan)endow it with the status of“gold among woods”.Wang Shixiang’s inscription binds the furniture to the cultural essence of“the charm of the Ming Dynasty”,transforming it into“heritable cultural heritage”.This paper provides a new perspective for the case study of Ming-style furniture and offers theoretical reference for the contemporary inheritance of traditional craftsmanship.展开更多
For mission-oriented unmanned aerial vehicle(UAV)swarms,mission capability assessment provides an important reference in the design and development process,and is a precondition for mission success.For this multi-crit...For mission-oriented unmanned aerial vehicle(UAV)swarms,mission capability assessment provides an important reference in the design and development process,and is a precondition for mission success.For this multi-criteria decisionmaking(MCDM)problem,the current literature lacks a way to unambiguously present criteria and the popular fuzzy analytic network process(ANP)approaches neglect the hesitancy of subjective judgments.To fill these research gaps,an MCDM method based on unified architecture framework(UAF)and interval-valued spherical fuzzy ANP(IVSF-ANP)is proposed in this paper.Firstly,selected viewpoints in UAF are extended to construct criteria models with standardized representation.Secondly,interval-valued spherical fuzzy sets are introduced to ANP to weight interdependent criteria,handling fuzziness and hesitancy in pairwise comparisons.A method of adjusting weights of experts based on their decision similarities is also included in this process to reduce ambiguity brought by multiple experts.Next,performance characteristics are non-linearly transformed regarding to expectations to get final results.This proposition is applied to assess the mission capability of UAV swarms to search and strike surface vessels.Comparative analysis shows that the proposed method is valid and reasonable.展开更多
The Nuo mask is the core visual vehicle within China’s Nuo culture and constitutes a complex symbolic system through facial features(icons),patterns(indexes),and colors(symbols).Within the context of intangible cultu...The Nuo mask is the core visual vehicle within China’s Nuo culture and constitutes a complex symbolic system through facial features(icons),patterns(indexes),and colors(symbols).Within the context of intangible cultural heritage(ICH)preservation,its value lies in the continuation and revitalization of its dynamic symbolic functions.Grounded in semiotic theory,this paper elaborates on three core dimensions of symbolic value manifested by Nuo masks in ICH preservation:a ritual symbol for living transmission,a symbol of identity for collective memory,and an aesthetic symbol as a source of creativity.展开更多
Due to the complexity of decision-making problems and the subjectivity of decision-makers in practical application,it is necessary to adopt different forms of information expression according to the actual situation o...Due to the complexity of decision-making problems and the subjectivity of decision-makers in practical application,it is necessary to adopt different forms of information expression according to the actual situation of specific decision-making problems and choose the best method to solve them.Multi-valued neutrosophic set,as an extension of neutrosophic set,can more effectively and accurately describe incomplete,uncertain or inconsistent information.TODIM and TOPSIS methods are two commonly used multi-attribute decision-making methods,each of which has its advantages and disadvantages.This paper proposes a new method based on TODIM and TOPSIS to solve multi-attribute decision-making problems under multi-valued neutrosophic environment.After introducing the related theory of multi-valued neutrosophic set and the traditional TODIM and TOPSIS methods,the new method based on a combination of TODIM and TOPSIS methods is described.And then,two illustrative examples proved the feasibility and validity of the proposed method.Finally,the result has been compared with some existing methods under the same examples and the proposed method’s superiority has been proved.This paper studies this kind of decision-making problem from algorithm idea,algorithm steps and decision-making influencing factors.展开更多
This paper proposes a multi-criteria decision-making (MCGDM) method based on the improved single-valued neutrosophic Hamacher weighted averaging (ISNHWA) operator and grey relational analysis (GRA) to overcome the lim...This paper proposes a multi-criteria decision-making (MCGDM) method based on the improved single-valued neutrosophic Hamacher weighted averaging (ISNHWA) operator and grey relational analysis (GRA) to overcome the limitations of present methods based on aggregation operators. First, the limitations of several existing single-valued neutrosophic weighted averaging aggregation operators (i.e. , the single-valued neutrosophic weighted averaging, single-valued neutrosophic weighted algebraic averaging, single-valued neutrosophic weighted Einstein averaging, single-valued neutrosophic Frank weighted averaging, and single-valued neutrosophic Hamacher weighted averaging operators), which can produce some indeterminate terms in the aggregation process, are discussed. Second, an ISNHWA operator was developed to overcome the limitations of existing operators. Third, the properties of the proposed operator, including idempotency, boundedness, monotonicity, and commutativity, were analyzed. Application examples confirmed that the ISNHWA operator and the proposed MCGDM method are rational and effective. The proposed improved ISNHWA operator and MCGDM method can overcome the indeterminate results in some special cases in existing single-valued neutrosophic weighted averaging aggregation operators and MCGDM methods.展开更多
The purpose of the research is to discuss the differentperformances of administrators’ values in different orga-nizations in Taiwan province and the determinants ofethics of administrators in decision - making. Throu...The purpose of the research is to discuss the differentperformances of administrators’ values in different orga-nizations in Taiwan province and the determinants ofethics of administrators in decision - making. Throughthe understanding of these issues, the research expects tohelp the internal operation of ethical behaviors in the or-ganization in order to establish business ethics. The re-search used empirical examination and stratified sam-pling to select 231 top, middle and low administrators inmanufacture, service, government and non - profit -making organizations as target. The result showed thatthe main determinant of ethics of administrators in deci-sion - making was "corporate interest". Besides, the ad-ministrators in the four organizations showed distinctivevalues. The non - profit - making organizations showedhigher sense of values such as"caring self - discipline"and "safety belonging"than profit - making groups did.展开更多
Fuzzy sets have undergone several expansions and generalisations in the literature,including Atanasov’s intuitionistic fuzzy sets,type 2 fuzzy sets,and fuzzy multisets,to name a few.They can be regarded as fuzzy mult...Fuzzy sets have undergone several expansions and generalisations in the literature,including Atanasov’s intuitionistic fuzzy sets,type 2 fuzzy sets,and fuzzy multisets,to name a few.They can be regarded as fuzzy multisets from a formal standpoint;nevertheless,their interpretation differs from the two other approaches to fuzzy multisets that are currently available.Hesitating fuzzy sets(HFS)are very useful if consultants have hesitation in dealing with group decision-making problems between several possible memberships.However,these possible memberships can be not only crisp values in[0,1],but also interval values during a practical evaluation process.Hesitant bipolar valued fuzzy set(HBVFS)is a generalization of HFS.This paper aims to introduce a general framework of multi-attribute group decision-making using social network.We propose two types of decision-making processes:Type-1 decision-making process and Type-2 decision-making process.In the Type-1 decision-making process,the experts’original opinion is proces for thefinal ranking of alternatives.In Type-2 decision making processs,there are two major aspects we consider.First,consistency tests and checking of consensus models are given for detecting that the judgments are logically rational.Otherwise,the framework demands(partial)decision-makers to review their assessments.Second,the coherence and consensus of several HBVFSs are established forfinal ranking of alternatives.The proposed framework is clarified by an example of software packages selection of a university.展开更多
A neutrosophic multi-valued set(NMVS)is a crucial representation for true,false,and indeterminate multivalued information.Then,a consistent single-valued neutrosophic set(CSVNS)can effectively reflect the mean and con...A neutrosophic multi-valued set(NMVS)is a crucial representation for true,false,and indeterminate multivalued information.Then,a consistent single-valued neutrosophic set(CSVNS)can effectively reflect the mean and consistency degree of true,false,and indeterminate multi-valued sequences and solve the operational issues between different multi-valued sequence lengths in NMVS.However,there has been no research on consistent single-valued neutrosophic similarity measures in the existing literature.This paper proposes cotangent similarity measures and weighted cotangent similarity measures between CSVNSs based on cotangent function in the neutrosophic multi-valued setting.The cosine similarity measures showthe cosine of the angle between two vectors projected into amultidimensional space,rather than their distance.The cotangent similaritymeasures in this study can alleviate several shortcomings of cosine similarity measures in vector space to a certain extent.Then,a decisionmaking approach is presented in viewof the established cotangent similarity measures in the case of NMVSs.Finally,the developed decision-making approach is applied to selection problems of potential cars.The proposed approach has obtained two different results,which have the same sort sequence as the compared literature.The decision results prove its validity and effectiveness.Meantime,it also provides a new manner for neutrosophic multi-valued decision-making issues.展开更多
In this study,the authors envisage the neutrosophic number from various distinct rational perspectives and viewpoints to give it a look of a conundrum.They focused and analysed neutrosophic fuzzy numbers when indeterm...In this study,the authors envisage the neutrosophic number from various distinct rational perspectives and viewpoints to give it a look of a conundrum.They focused and analysed neutrosophic fuzzy numbers when indeterminacy and falsity functions are dependent on each other,which serves an indispensable role for the uncertainty concept.Additionally,the idea of cylindrical neutrosophic single-valued number is focused here,when the indeterminacy and falsity functions are dependent to each other using an influx of different logical and innovative graphical representation.They also developed the score and accuracy function for this particular cylindrical neutrosophic single-valued number and analysed some real-life problems like networking critical path model problem and minimal spanning tree problem of operation research field when the numbers are in cylindrical neutrosophic ambiance.They also introduced a multi-criterion group decision-making problem in this cylindrical neutrosophic domain.This noble thought will help us to solve a plethora of daily life problems in the neutrosophic arena.展开更多
With the goal of“carbon peaking and carbon neutralization”,it is an inevitable trend for investing smart grid to promote the large-scale grid connection of renewable energy.Smart grid investment has a significant dr...With the goal of“carbon peaking and carbon neutralization”,it is an inevitable trend for investing smart grid to promote the large-scale grid connection of renewable energy.Smart grid investment has a significant driving effect(derivative value),and evaluating this value can help to more accurately grasp the external effects of smart grid investment and support the realization of industrial linkage value with power grid investment as the core.Therefore,by analyzing the characterization of the derivative value of smart grid driven by investment,this paper constructs the evaluation index system of the derivative value of smart grid investment including 11 indicators.Then,the hybrid evaluation model of the derivative value of smart grid investment is developed based on anti-entropy weight(AEW),level based weight assessment(LBWA),and measurement alternatives and ranking according to the compromise solution(MARCOS)techniques.The results of case analysis show that for SG investment,the value of sustainable development can better reflect its derivative value,and when smart grid performs poorly in promoting renewable energy consumption,improving primary energy efficiency,and improving its own fault resistance,the driving force of its investment for future sustainable development will decline significantly,making the grid investment lack derivative value.In addition,smart grid investment needs to pay attention to the economy of investment,which is an important guarantee to ensure that the power grid has sufficient and stable sources of investment funds.Finally,compared with three comparison models,the proposed hybrid multi-criteria decision-making(MCDM)model can better improve the decision-making efficiency on the premise of ensuring robustness.展开更多
The critical role of patient-reported outcome measures(PROMs)in enhancing clinical decision-making and promoting patient-centered care has gained a profound significance in scientific research.PROMs encapsulate a pati...The critical role of patient-reported outcome measures(PROMs)in enhancing clinical decision-making and promoting patient-centered care has gained a profound significance in scientific research.PROMs encapsulate a patient's health status directly from their perspective,encompassing various domains such as symptom severity,functional status,and overall quality of life.By integrating PROMs into routine clinical practice and research,healthcare providers can achieve a more nuanced understanding of patient experiences and tailor treatments accordingly.The deployment of PROMs supports dynamic patient-provider interactions,fostering better patient engagement and adherence to tre-atment plans.Moreover,PROMs are pivotal in clinical settings for monitoring disease progression and treatment efficacy,particularly in chronic and mental health conditions.However,challenges in implementing PROMs include data collection and management,integration into existing health systems,and acceptance by patients and providers.Overcoming these barriers necessitates technological advancements,policy development,and continuous education to enhance the acceptability and effectiveness of PROMs.The paper concludes with recommendations for future research and policy-making aimed at optimizing the use and impact of PROMs across healthcare settings.展开更多
文摘Objective To evaluate the clinical value of siltuximab in the treatment of Castleman disease based on multicriteria decision analysis(MCDA)and evidence and value:Impact on decision making(EVIDEM)framework.Methods The evidence matrix for quantitative analysis of MCDA was extracted through literature research,and the weight of each evaluation index was calculated by the maximum differentiation measure in conjoint analysis.Besides,the clinical value of siltuximab in the treatment of Castleman disease was analyzed quantitatively and qualitatively based on the results of expert questionnaire surveys.Results and Conclusion The clinical value score of siltuximab was 0.491,and the weight ratio of“therapeutic benefit”(15.39%),“drug effectiveness”(14.46%)and“drug safety”(11.43%)were the three largest.Among the indexes of“drug effectiveness”“drug safety”“patient reported outcome”“therapeutic benefit”and“non-medical cost”,siltuximab for Castleman disease was considered to be a more valuable treatment option than other first-line therapies.By qualitative analysis,57%experts believed that siltuximab was a better treatment option.The indexes that contribute the most to the overall clinical value of siltuximab are“therapeutic benefit”“drug effectiveness”and“quality of evidence”,while the indexes that have a negative impact on the clinical value of siltuximab is“drug treatment cost”.
基金supported by the Princess Nourah bint Abdulrahman University Researchers Supporting Project number(PNURSP2026R259)Princess Nourah bint Abdulrahman University,Riyadh,Saudi Arabia.Ashit Kumar Dutta would like to thank AlMaarefa University for supporting this research under project number MHIRSP2025017.
文摘Environmental problems are intensifying due to the rapid growth of the population,industry,and urban infrastructure.This expansion has resulted in increased air and water pollution,intensified urban heat island effects,and greater runoff from parks and other green spaces.Addressing these challenges requires prioritizing green infrastructure and other sustainable urban development strategies.This study introduces a novel Integrated Decision Support System that combines Pythagorean Fuzzy Sets with the Advanced Alternative Ranking Order Method allowing for Two-Step Normalization(AAROM-TN),enhanced by a dual weighting strategy.The weighting approach integrates the Criteria Importance Through Intercriteria Correlation(CRITIC)method with the Criteria Importance through Means and Standard Deviation(CIMAS)technique.The originality of the proposed framework lies in its ability to objectively quantify criteria importance using CRITIC,incorporate decision-makers’preferences through CIMAS,and capture the uncertainty and hesitation inherent in human judgment via Pythagorean Fuzzy Sets.A case study evaluating green infrastructure alternatives in metropolitan regions demonstrates the applicability and effectiveness of the framework.A sensitivity analysis is conducted to examine how variations in criteria weights affect the rankings and to evaluate the robustness of the results.Furthermore,a comparative analysis highlights the practical and financial implications of each alternative by assessing their respective strengths and weaknesses.
基金Project supported by the National Natural Science Foun-dation of China(Grant Nos.62371199 and 62071186)the Natural Science Foundation of Guangdong Province,China(Grant No.2024A1515012427)+1 种基金the Quantum Science Strate-gic Initiative Project of Guangdong Province,China(Grant No.GDZX2305001)the Key Laboratory Project of Guangdong Province,China(Grant No.2020B1212060066).
文摘Weak measurement offers a powerful framework for probing nonclassical features of quantum mechanics,with anomalous weak values serving as operational signatures of contextuality.While the anomalous weak value verification of quantum contextuality has been predominantly investigated in the single-photon regime and analyzed under approximation condition of infinitesimally small perturbation strength.This study releases the approximation condition and takes into account the impact of perturbation strength on the rigor of the verification.And the investigation on the verification of contextuality is extended to the multi-photon scenarios for observing the influence of the correlation between photons on the verification.Without the limitation of infinitesimally small probability of disturbance,anomalous weak values are identified as necessary for contextuality to emerge,thereby refining the criterion proposed by Pusey[Phys.Rev.Lett.113200401(2014)].In the multi-photon scenarios,the emergence of contextuality also depends strongly on both the photon number and the photon-number distribution state.In particular,contextuality is found to be maximized when the single-photon component dominates and the second-order correlation is lower.These results highlight the critical role of photon statistics in experimental tests of contextuality via anomalous weak values.
基金funded by scientific research projects under Grant JY2024B011.
文摘With the increasing complexity of industrial automation,planetary gearboxes play a vital role in largescale equipment transmission systems,directly impacting operational efficiency and safety.Traditional maintenance strategies often struggle to accurately predict the degradation process of equipment,leading to excessive maintenance costs or potential failure risks.However,existing prediction methods based on statistical models are difficult to adapt to nonlinear degradation processes.To address these challenges,this study proposes a novel condition-based maintenance framework for planetary gearboxes.A comprehensive full-lifecycle degradation experiment was conducted to collect raw vibration signals,which were then processed using a temporal convolutional network autoencoder with multi-scale perception capability to extract deep temporal degradation features,enabling the collaborative extraction of longperiod meshing frequencies and short-term impact features from the vibration signals.Kernel principal component analysis was employed to fuse and normalize these features,enhancing the characterization of degradation progression.A nonlinear Wiener process was used to model the degradation trajectory,with a threshold decay function introduced to dynamically adjust maintenance strategies,and model parameters optimized through maximum likelihood estimation.Meanwhile,the maintenance strategy was optimized to minimize costs per unit time,determining the optimal maintenance timing and preventive maintenance threshold.The comprehensive indicator of degradation trends extracted by this method reaches 0.756,which is 41.2%higher than that of traditional time-domain features;the dynamic threshold strategy reduces the maintenance cost per unit time to 55.56,which is 8.9%better than that of the static threshold optimization.Experimental results demonstrate significant reductions in maintenance costs while enhancing system reliability and safety.This study realizes the organic integration of deep learning and reliability theory in the maintenance of planetary gearboxes,provides an interpretable solution for the predictive maintenance of complex mechanical systems,and promotes the development of condition-based maintenance strategies for planetary gearboxes.
文摘AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control study included participants who underwent routine complete blood count testing.Inflammation-related indices,including neutrophil-to-lymphocyte ratio,systemic immune-inflammation index(SII),and PIV,were derived and analyzed.Receiver operating characteristic curve(ROC)analysis was applied to assess the diagnostic performance of these indices in distinguishing patients with PDR,with sensitivity,specificity,area under ROC,and optimal threshold values calculated.In addition,binary logistic regression analysis was performed to evaluate the association between inflammatory indices and PDR stage.RESULTS:This study included 205 patients:60 with diabetes without retinopathy(mean age:61.81±10.76y),80 with PDR(mean age:61.63±10.03y)and 65 healthy controls(mean age:59.52±5.88y).The PDR group had significantly higher white blood cell(WBC,P<0.001),monocyte(MONO,P=0.009)and neutrophil(NEU)counts(P<0.001).SII and PIV had the highest sensitivity and area under ROC for predicting patients with PDR(0.822,0.846,respectively).The optimal cut-off values for discriminating patients with PDR were determined to be>527.12 and>299.08 for SII and PIV,respectively.The logistic regression analysis demonstrated that a decrease in lymphocyte(LYM)count and an increase in platelet count(PLT),glycated haemoglobin(HbA1c),SII,and PIV were all significantly associated with the development of high-risk PDR(all P<0.05).PIV was more stable than independent MONO,LYM,PLT and NEU levels in predicting both the diagnosis and stage of PDR.The optimal cut-off value for PIV to discriminate patients with high-risk PDR was found to be>345.87 area under ROC=0.871,with sensitivity of 0.827 and specificity of 0.812.CONCLUSION:PIV is a reliable,valuable,and inexpensive blood index that can be used for early detection and staging of PDR.PIV may therefore be essential to be used for the follow-up of diabetic patients.
基金supported by the National Natural Science Foundation of China(11601525)the Natural Science Foundation of Hunan Province(2024JJ5412),the Changsha Municipal Natural Science Foundation(kq2402193).
文摘In this paper,we study the nonlinear Riemann boundary value problem with square roots that is represented by a Cauchy-type integral with kernel density in variable exponent Lebesgue spaces.We discuss the odd-order zero-points distribution of the solutions and separate the single valued analytic branch of the solutions with square roots,then convert the problem to a Riemann boundary value problem in variable exponent Lebesgue spaces and discuss the singularity of solutions at individual zeros belonging to curve.We consider two types of cases those where the coefficient is Hölder and those where it is piecewise Hölder.Then we solve the Hilbert boundary value problem with square roots in variable exponent Lebesgue spaces.By discussing the distribution of the odd-order zero-points for solutions and the method of symmetric extension,we convert the Hilbert problem to a Riemann boundary value problem.The equivalence of the transformation is discussed.Finally,we get the solvable conditions and the direct expressions of the solutions in variable exponent Lebesgue spaces.
基金Under the auspices of the Key Projects of Philosophy and Social Sciences Research,Ministry of Education of China(No.23JZD008)National Natural Science Foundation of China(No.42171193)+2 种基金Key Project of Guangdong Provincial Philosophy and Social Sciences Planning(No.GD24ES013,GD25ZX04)2025 Guangzhou Basic and Applied Basic Research Special Project(No.2025A04J7127)Fundamental Research Funds for the Central Universities,Sun Yat-sen University(No.24wkjc11)。
文摘The shift toward specialized and large-scale agricultural production has spurred the emergence of agricultural clusters as key forces of rural vitalization and sustainable development.This paper explored the formation and evolution of Meizhou pomelo industry cluster in China,focusing on its role in restructuring rural socio-economic systems and integrating the whole value chains.Based on a case study employing qualitative methods such as in-depth interviews and participatory observation,the agricultural cluster evolution of Meizhou pomelo was categorized into three key phases of initial decentralization,self-organized scaling,and reorganized clustering.Geographical proximity and industrial agglomeration constitute the physical foundation,while vertical/horizontal linkages,technologic-al innovation,and policy support enhance competitiveness.Special mechanisms emerge through localized social networks,farmer co-operatives’activation,and cross-regional market expansion.The cluster’s impact is manifested in the shift from extensive to standard-ized and modernized production,diversified and flexible livelihood of farmers,and the integration of agriculture with industry and ser-vices.The development of the whole value chain based on agricultural cluster represents a critical pathway for achieving agricultural modernization,encompassing both internal and external value chain optimization.Through quality assurance systems,product diversi-fication strategies,operational efficiency improvements,and brand enhancement,these clusters amplify product value propositions and market competitiveness.This systemic approach facilitates supply-demand coordination,enables resource synergies,and optimizes eco-nomic returns across the horizontal and vertical value chain.This paper argues that agricultural clusters serve as strategic catalysts for sustainable rural development by reconstructing local production systems,fostering innovation ecosystems,and aligning agricultural modernization.It contributes to debates on rural vitalization by demonstrating how agricultural clustering can reconfigure rural areas as hubs of ecological modernization,rather than mere urban peripheries.
文摘The Double Take column looks at a single topic from an African and Chinese perspective.This month,we discuss how to understand the growing emphasis on emotional returns among young people.Emotional value has emerged as a central force shaping youth decision-making across work,consumption,relationships and lifestyle choices.Unlike traditional economic rationality that prioritises income and material security,emotional value focuses on how choices make individuals feel and how they align with personal meaning.This shift is particularly evident in rapidly transforming societies such as China and Ghana,where economic restructuring,globalisation and social change have reshaped pathways to adulthood.
基金supported by the Deanship of Graduate Studies and Scientific Research at Qassim University(QU-APC-2024-9/1).
文摘Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such uncertainties.This study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and AND-operations.Some results related to these operations are also modified for pPyFHSS.Additionally,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and results.Lastly,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested system.The algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical models.Similarly,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison.
文摘Ming-style furniture represents the pinnacle of Chinese traditional furniture,with the four-head official’s cap chair standing out as a representative category due to its classic form and cultural connotations.This paper takes a specific rosewood four-head official’s cap chair inscribed by Wang Shixiang as the research subject,employing a tripartite approach of form analysis,material examination,and inscription interpretation.The chair strictly adheres to the classic form of Ming-style four-head official’s cap chairs,embodying the Ming Dynasty design philosophy of“the unity of function and aesthetics”.The scarcity and unique grain pattern of the golden-flecked rosewood(Zitan)endow it with the status of“gold among woods”.Wang Shixiang’s inscription binds the furniture to the cultural essence of“the charm of the Ming Dynasty”,transforming it into“heritable cultural heritage”.This paper provides a new perspective for the case study of Ming-style furniture and offers theoretical reference for the contemporary inheritance of traditional craftsmanship.
基金supported by the National Natural Science Foundation of China(62073267,61903305)the Fundamental Research Funds for the Central Universities(HXGJXM202214)。
文摘For mission-oriented unmanned aerial vehicle(UAV)swarms,mission capability assessment provides an important reference in the design and development process,and is a precondition for mission success.For this multi-criteria decisionmaking(MCDM)problem,the current literature lacks a way to unambiguously present criteria and the popular fuzzy analytic network process(ANP)approaches neglect the hesitancy of subjective judgments.To fill these research gaps,an MCDM method based on unified architecture framework(UAF)and interval-valued spherical fuzzy ANP(IVSF-ANP)is proposed in this paper.Firstly,selected viewpoints in UAF are extended to construct criteria models with standardized representation.Secondly,interval-valued spherical fuzzy sets are introduced to ANP to weight interdependent criteria,handling fuzziness and hesitancy in pairwise comparisons.A method of adjusting weights of experts based on their decision similarities is also included in this process to reduce ambiguity brought by multiple experts.Next,performance characteristics are non-linearly transformed regarding to expectations to get final results.This proposition is applied to assess the mission capability of UAV swarms to search and strike surface vessels.Comparative analysis shows that the proposed method is valid and reasonable.
基金National Social Science Fund project“Research on the Narrative of the Sense of Community for the Chinese Nation in Southwest Nuo Opera”(24XMZ063).
文摘The Nuo mask is the core visual vehicle within China’s Nuo culture and constitutes a complex symbolic system through facial features(icons),patterns(indexes),and colors(symbols).Within the context of intangible cultural heritage(ICH)preservation,its value lies in the continuation and revitalization of its dynamic symbolic functions.Grounded in semiotic theory,this paper elaborates on three core dimensions of symbolic value manifested by Nuo masks in ICH preservation:a ritual symbol for living transmission,a symbol of identity for collective memory,and an aesthetic symbol as a source of creativity.
基金This research was funded by the Humanities and Social Sciences Foundation of Ministry of Education of the Peoples Republic of China(17YJA630115)The recipient of the founding is DX.
文摘Due to the complexity of decision-making problems and the subjectivity of decision-makers in practical application,it is necessary to adopt different forms of information expression according to the actual situation of specific decision-making problems and choose the best method to solve them.Multi-valued neutrosophic set,as an extension of neutrosophic set,can more effectively and accurately describe incomplete,uncertain or inconsistent information.TODIM and TOPSIS methods are two commonly used multi-attribute decision-making methods,each of which has its advantages and disadvantages.This paper proposes a new method based on TODIM and TOPSIS to solve multi-attribute decision-making problems under multi-valued neutrosophic environment.After introducing the related theory of multi-valued neutrosophic set and the traditional TODIM and TOPSIS methods,the new method based on a combination of TODIM and TOPSIS methods is described.And then,two illustrative examples proved the feasibility and validity of the proposed method.Finally,the result has been compared with some existing methods under the same examples and the proposed method’s superiority has been proved.This paper studies this kind of decision-making problem from algorithm idea,algorithm steps and decision-making influencing factors.
文摘This paper proposes a multi-criteria decision-making (MCGDM) method based on the improved single-valued neutrosophic Hamacher weighted averaging (ISNHWA) operator and grey relational analysis (GRA) to overcome the limitations of present methods based on aggregation operators. First, the limitations of several existing single-valued neutrosophic weighted averaging aggregation operators (i.e. , the single-valued neutrosophic weighted averaging, single-valued neutrosophic weighted algebraic averaging, single-valued neutrosophic weighted Einstein averaging, single-valued neutrosophic Frank weighted averaging, and single-valued neutrosophic Hamacher weighted averaging operators), which can produce some indeterminate terms in the aggregation process, are discussed. Second, an ISNHWA operator was developed to overcome the limitations of existing operators. Third, the properties of the proposed operator, including idempotency, boundedness, monotonicity, and commutativity, were analyzed. Application examples confirmed that the ISNHWA operator and the proposed MCGDM method are rational and effective. The proposed improved ISNHWA operator and MCGDM method can overcome the indeterminate results in some special cases in existing single-valued neutrosophic weighted averaging aggregation operators and MCGDM methods.
文摘The purpose of the research is to discuss the differentperformances of administrators’ values in different orga-nizations in Taiwan province and the determinants ofethics of administrators in decision - making. Throughthe understanding of these issues, the research expects tohelp the internal operation of ethical behaviors in the or-ganization in order to establish business ethics. The re-search used empirical examination and stratified sam-pling to select 231 top, middle and low administrators inmanufacture, service, government and non - profit -making organizations as target. The result showed thatthe main determinant of ethics of administrators in deci-sion - making was "corporate interest". Besides, the ad-ministrators in the four organizations showed distinctivevalues. The non - profit - making organizations showedhigher sense of values such as"caring self - discipline"and "safety belonging"than profit - making groups did.
基金This paper was supported by Wonkwang University in 2022.
文摘Fuzzy sets have undergone several expansions and generalisations in the literature,including Atanasov’s intuitionistic fuzzy sets,type 2 fuzzy sets,and fuzzy multisets,to name a few.They can be regarded as fuzzy multisets from a formal standpoint;nevertheless,their interpretation differs from the two other approaches to fuzzy multisets that are currently available.Hesitating fuzzy sets(HFS)are very useful if consultants have hesitation in dealing with group decision-making problems between several possible memberships.However,these possible memberships can be not only crisp values in[0,1],but also interval values during a practical evaluation process.Hesitant bipolar valued fuzzy set(HBVFS)is a generalization of HFS.This paper aims to introduce a general framework of multi-attribute group decision-making using social network.We propose two types of decision-making processes:Type-1 decision-making process and Type-2 decision-making process.In the Type-1 decision-making process,the experts’original opinion is proces for thefinal ranking of alternatives.In Type-2 decision making processs,there are two major aspects we consider.First,consistency tests and checking of consensus models are given for detecting that the judgments are logically rational.Otherwise,the framework demands(partial)decision-makers to review their assessments.Second,the coherence and consensus of several HBVFSs are established forfinal ranking of alternatives.The proposed framework is clarified by an example of software packages selection of a university.
文摘A neutrosophic multi-valued set(NMVS)is a crucial representation for true,false,and indeterminate multivalued information.Then,a consistent single-valued neutrosophic set(CSVNS)can effectively reflect the mean and consistency degree of true,false,and indeterminate multi-valued sequences and solve the operational issues between different multi-valued sequence lengths in NMVS.However,there has been no research on consistent single-valued neutrosophic similarity measures in the existing literature.This paper proposes cotangent similarity measures and weighted cotangent similarity measures between CSVNSs based on cotangent function in the neutrosophic multi-valued setting.The cosine similarity measures showthe cosine of the angle between two vectors projected into amultidimensional space,rather than their distance.The cotangent similaritymeasures in this study can alleviate several shortcomings of cosine similarity measures in vector space to a certain extent.Then,a decisionmaking approach is presented in viewof the established cotangent similarity measures in the case of NMVSs.Finally,the developed decision-making approach is applied to selection problems of potential cars.The proposed approach has obtained two different results,which have the same sort sequence as the compared literature.The decision results prove its validity and effectiveness.Meantime,it also provides a new manner for neutrosophic multi-valued decision-making issues.
文摘In this study,the authors envisage the neutrosophic number from various distinct rational perspectives and viewpoints to give it a look of a conundrum.They focused and analysed neutrosophic fuzzy numbers when indeterminacy and falsity functions are dependent on each other,which serves an indispensable role for the uncertainty concept.Additionally,the idea of cylindrical neutrosophic single-valued number is focused here,when the indeterminacy and falsity functions are dependent to each other using an influx of different logical and innovative graphical representation.They also developed the score and accuracy function for this particular cylindrical neutrosophic single-valued number and analysed some real-life problems like networking critical path model problem and minimal spanning tree problem of operation research field when the numbers are in cylindrical neutrosophic ambiance.They also introduced a multi-criterion group decision-making problem in this cylindrical neutrosophic domain.This noble thought will help us to solve a plethora of daily life problems in the neutrosophic arena.
文摘With the goal of“carbon peaking and carbon neutralization”,it is an inevitable trend for investing smart grid to promote the large-scale grid connection of renewable energy.Smart grid investment has a significant driving effect(derivative value),and evaluating this value can help to more accurately grasp the external effects of smart grid investment and support the realization of industrial linkage value with power grid investment as the core.Therefore,by analyzing the characterization of the derivative value of smart grid driven by investment,this paper constructs the evaluation index system of the derivative value of smart grid investment including 11 indicators.Then,the hybrid evaluation model of the derivative value of smart grid investment is developed based on anti-entropy weight(AEW),level based weight assessment(LBWA),and measurement alternatives and ranking according to the compromise solution(MARCOS)techniques.The results of case analysis show that for SG investment,the value of sustainable development can better reflect its derivative value,and when smart grid performs poorly in promoting renewable energy consumption,improving primary energy efficiency,and improving its own fault resistance,the driving force of its investment for future sustainable development will decline significantly,making the grid investment lack derivative value.In addition,smart grid investment needs to pay attention to the economy of investment,which is an important guarantee to ensure that the power grid has sufficient and stable sources of investment funds.Finally,compared with three comparison models,the proposed hybrid multi-criteria decision-making(MCDM)model can better improve the decision-making efficiency on the premise of ensuring robustness.
文摘The critical role of patient-reported outcome measures(PROMs)in enhancing clinical decision-making and promoting patient-centered care has gained a profound significance in scientific research.PROMs encapsulate a patient's health status directly from their perspective,encompassing various domains such as symptom severity,functional status,and overall quality of life.By integrating PROMs into routine clinical practice and research,healthcare providers can achieve a more nuanced understanding of patient experiences and tailor treatments accordingly.The deployment of PROMs supports dynamic patient-provider interactions,fostering better patient engagement and adherence to tre-atment plans.Moreover,PROMs are pivotal in clinical settings for monitoring disease progression and treatment efficacy,particularly in chronic and mental health conditions.However,challenges in implementing PROMs include data collection and management,integration into existing health systems,and acceptance by patients and providers.Overcoming these barriers necessitates technological advancements,policy development,and continuous education to enhance the acceptability and effectiveness of PROMs.The paper concludes with recommendations for future research and policy-making aimed at optimizing the use and impact of PROMs across healthcare settings.
