Commercial phosphor-converted white LEDs(pc-WLEDs)face two inherent limitations,namely blue light hazard and low color rendering index,due to the use of blue LEDs as excitation source.To address these challenges,viole...Commercial phosphor-converted white LEDs(pc-WLEDs)face two inherent limitations,namely blue light hazard and low color rendering index,due to the use of blue LEDs as excitation source.To address these challenges,violet LEDs are proposed as an alternative solution.Currently,phosphors that can be efficiently excited by violet light(with wavelengths from 400 to 420 nm)remain under development still.In this study,we utilize large language models to construct a comprehensive database of Eu^(2+)and Ce^(3+)doped phosphors for discovering novel violet-excited phosphors.A total of 822 phosphor data entries,including elemental compositions,crystal structures and excitation/emission wavelengths,have been extracted and validated from 9551 research papers.Compared with Ce^(3+)doped phosphors,the Eu^(2+)are in general more suited for violet-excited phosphors,as well as red-emitting phosphors.In particular,Eu^(2+)doped nitrides and sulfides are worth of exploration for violet-excited phosphors.This database is expected to be useful in the future development of phosphors for pc-WLEDs based on artificial intelligence methods.The datasets in this article are listed in Science Data Bank at http://doi.org/10.57760/sciencedb.34314.展开更多
Background:The purpose of this study was to analyze and classify adverse drug events(ADEs)related to ceftazidime/avibactam reported in the Food and Drug Administration Adverse Event Reporting System(FAERS)database and...Background:The purpose of this study was to analyze and classify adverse drug events(ADEs)related to ceftazidime/avibactam reported in the Food and Drug Administration Adverse Event Reporting System(FAERS)database and to evaluate their potential safety signals since the drug’s market introduction.Methods:This analysis systematically extracted and filtered FAERS data for ceftazidime/avibactam from its market launch in 2015 to the last quarter of 2024,utilizing the Medical Dictionary for Regulatory Activities(MedDRA)terminology for ADE recoding.The analysis employed the reporting odds ratio(ROR)method to assess the strength of ADE signals and to identify significant diseases associated with infections,the hepatobiliary system,the urinary system,and the nervous system.Results:A review of 540 adverse reaction reports revealed significant signals of adverse effects related to infections,hepatobiliary disorders,urinary system issues,and neurological impairments,including pathogen resistance,liver and kidney function impairment,encephalopathy,thrombocytopenia,and toxic epidermal necrolysis.However,these issues require further clinical attention.Conclusion:Ceftazidime/avibactam is associated with a range of adverse reactions,necessitating enhanced clinical monitoring,particularly in patients with underlying liver or kidney dysfunction.Continuous risk assessment and vigilant monitoring are critical for its clinical use.However,this study is limited by inherent reporting biases and confounders associated with the spontaneous reporting database(FAERS).Future research should validate these signals through prospective cohort and mechanistic studies and explore personalized risk management strategies for high-risk populations.展开更多
This study proposes a new post-tensioned precast bridge column(PT-PBC)with a socket connection.Compared to conventional PBCs connected by PT tendons,the combination of the PT tendons with the socket connection can avo...This study proposes a new post-tensioned precast bridge column(PT-PBC)with a socket connection.Compared to conventional PBCs connected by PT tendons,the combination of the PT tendons with the socket connection can avoid tensioning the PT tendons on site,which further accelerates construction speed while improving construction quality and safety.In addition,compared to conventional PBCs with a socket connection,a rocking interface can avoid the formation of a plastic hinge in a column,which greatly alleviates seismic damage to that area.One specimen for quasi-static testing is used to validate the feasibility of this connection type.Subsequently,finite element models(FEM)are established to systematically predict the responses of the proposed columns under lateral cyclic loading.The accuracy of the FEM is verified through quasistatic testing.Next,the influences of the key design parameters of the PT-PBC,including the area ratio and prestress level of the PT tendons,the area ratio of energy dissipation(ED)steel rebars,and the total axial compression ratio on the seismic performances of PT-PBC are systematically investigated.The use of shape memory alloy(SMA)rods as energy dissipation devices and their performances also are investigated.The results show that increasing the area ratio and prestress level of PT tendons has an overall positive impact on the self-centering capacity of the column.The prestress level of PT tendons should be kept between 35%and 55%,depending on different conditions.The total compression axial ratio of the columns should be maintained between 0.3 and 0.4.Both ED steel rebars and SMA rods can boost the column’s energy dissipation capacity,while SMA rods can reduce residual deformation due to their inherent mechanical properties.展开更多
Background:Social connection is widely recognized as a protective determinant of health,yet its direct and indirect effects on mental health remain underexplored.This study examines the relationship between social con...Background:Social connection is widely recognized as a protective determinant of health,yet its direct and indirect effects on mental health remain underexplored.This study examines the relationship between social connection and mental health,focusing on the mediating role of quality of life(QoL)and the moderating effect of regional differences.Methods:We analyzed data from the 2019 Korean Community Health Survey,comprising 229,099 adults.Mental health was assessed through validated measures of depressive symptoms and psychological well-being.Social connection was measured using indicators of interpersonal ties and community participation,and QoL was assessed via self-reported health-related satisfaction across major life domains.Analytical procedures included mediation modeling and subgroup analyses by region,with significance levels set at p<0.05.Results:The results indicate that social connections are significantly associated with lower stress levels and reduced depressive symptoms,with QoL playing a critical mediating role.Notably,the indirect effect of social connection on mental health via QoL is stronger in rural areas compared to urban regions,highlighting the importance of social cohesion and community support in mental well-being.Among 203,567 adults,greater social participation was associated with lower subjective stress(total effect=−0.052,p<0.001)and fewer depressive symptoms(PHQ-9 total effect=−0.308,p<0.001).QoL significantly mediated these associations,with the strongest indirect pathways observed through usual activities(19.2%for stress;27.6%for depression)and mobility(24.4%for depression).Regional analysis showed stronger mediation in rural areas(up to 26.8%for stress and 32.6%for depression)than in urban areas(8–16%and 14.9–23%).Direct effects remained significant,indicating partial mediation.These findings highlight that social participation enhances mental health directly and indirectly through QoL,particularly in rural contexts.Conclusions:Social connection contributes to better mental health both directly and indirectly through improved QoL,with stronger effects observed in rural communities.These findings highlight the importance of fostering social cohesion and enhancing life quality as strategies for improving population mental health.Policy interventions should adopt context-sensitive approaches that account for regional differences in social resources and service availability.展开更多
Aiming at the problem of potential information noise introduced during the generation of ghost feature maps in GhostNet,this paper proposes a novel lightweight neural network model called ResghostNet.This model constr...Aiming at the problem of potential information noise introduced during the generation of ghost feature maps in GhostNet,this paper proposes a novel lightweight neural network model called ResghostNet.This model constructs the Resghost Module by combining residual connections and Adaptive-SE Blocks,which enhances the quality of generated feature maps through direct propagation of original input information and selection of important channels before cheap operations.Specifically,ResghostNet introduces residual connections on the basis of the Ghost Module to optimize the information flow,and designs a weight self-attention mechanism combined with SE blocks to enhance feature expression capabilities in cheap operations.Experimental results on the ImageNet dataset show that,compared to GhostNet,ResghostNet achieves higher accuracy while reducing the number of parameters by 52%.Although the computational complexity increases,by optimizing the usage strategy of GPU cachememory,themodel’s inference speed becomes faster.The ResghostNet is optimized in terms of classification accuracy and the number of model parameters,and shows great potential in edge computing devices.展开更多
The Wilczek–Zee connection(WZC)is a key concept in the study of topology of quantum systems.Here,we introduce the double Wilczek–Zee connection(DWZC)which naturally appears in the pure-state quantum geometric tensor...The Wilczek–Zee connection(WZC)is a key concept in the study of topology of quantum systems.Here,we introduce the double Wilczek–Zee connection(DWZC)which naturally appears in the pure-state quantum geometric tensor(QGT),another important concept in the field of quantum geometry.The DWZC is Hermitian with respect to the two integer indices,just like the original Hermitian WZC.Based on the symmetric logarithmic derivative operator,we propose a mixed-state quantum geometric tensor.Using the symmetric properties of the DWZC,we find that the real part of the QGT is connected to the real part of the DWZC and the square of eigenvalue differences of the density matrix,whereas the imaginary part can be given in terms of the imaginary part of the DWZC and the cube of the eigenvalue differences.For density matrices with full rank or no full rank,the QGT can be given in terms of real and imaginary parts of the DWZC.展开更多
Yunhe County in Lishui City,southwestern Zhejiang Province,doesn’t have any Disney castles.Instead,it has built bridges to the world with wood.Known as“China’s town of wooden toys,”accounting for about 40 percent ...Yunhe County in Lishui City,southwestern Zhejiang Province,doesn’t have any Disney castles.Instead,it has built bridges to the world with wood.Known as“China’s town of wooden toys,”accounting for about 40 percent of the global wooden toy market,Yunhe’s story began with a small factory established in 1970.Today,it has grown into a distinctive industrial cluster with an annual output value exceeding 8 billion yuan($1.15 billion),exporting products to 82 countries and regions.展开更多
Founded in September 2020,the International SparkLink Alliance(iSLA)now has approximately 1,200 members in diverse sectors including terminals,homes,vehicles,manufacturing,transportation,finance and healthcare.The iSL...Founded in September 2020,the International SparkLink Alliance(iSLA)now has approximately 1,200 members in diverse sectors including terminals,homes,vehicles,manufacturing,transportation,finance and healthcare.The iSLA has established a technical standards system for wireless short-range communication covering full-stack standards such as the end-to-end protocol system.展开更多
Research into metamorphism plays a pivotal role in reconstructing the evolution of continent,particularly through the study of ancient rocks that are highly susceptible to metamorphic alterations due to multiple tecto...Research into metamorphism plays a pivotal role in reconstructing the evolution of continent,particularly through the study of ancient rocks that are highly susceptible to metamorphic alterations due to multiple tectonic activities.In the big data era,the establishment of new data platforms and the application of big data methods have become a focus for metamorphic rocks.Significant progress has been made in creating specialized databases,compiling comprehensive datasets,and utilizing data analytics to address complex scientific questions.However,many existing databases are inadequate in meeting the specific requirements of metamorphic research,resulting from a substantial amount of valuable data remaining uncollected.Therefore,constructing new databases that can cope with the development of the data era is necessary.This article provides an extensive review of existing databases related to metamorphic rocks and discusses data-driven studies in this.Accordingly,several crucial factors that need to be taken into consideration in the establishment of specialized metamorphic databases are identified,aiming to leverage data-driven applications to achieve broader scientific objectives in metamorphic research.展开更多
BACKGROUND Ampullary adenocarcinoma is a rare malignant tumor of the gastrointestinal tract.Currently,only a few cases have been reported,resulting in limited information on survival.AIM To develop a dynamic nomogram ...BACKGROUND Ampullary adenocarcinoma is a rare malignant tumor of the gastrointestinal tract.Currently,only a few cases have been reported,resulting in limited information on survival.AIM To develop a dynamic nomogram using internal and external validation to predict survival in patients with ampullary adenocarcinoma.METHODS Data were sourced from the surveillance,epidemiology,and end results stat database.The patients in the database were randomized in a 7:3 ratio into training and validation groups.Using Cox regression univariate and multivariate analyses in the training group,we identified independent risk factors for overall survival and cancer-specific survival to develop the nomogram.The nomogram was validated with a cohort of patients from the First Affiliated Hospital of the Army Medical University.RESULTS For overall and cancer-specific survival,12(sex,age,race,lymph node ratio,tumor size,chemotherapy,surgical modality,T stage,tumor differentiation,brain metastasis,lung metastasis,and extension)and 6(age;surveillance,epidemiology,and end results stage;lymph node ratio;chemotherapy;surgical modality;and tumor differentiation)independent risk factors,respectively,were incorporated into the nomogram.The area under the curve values at 1,3,and 5 years,respectively,were 0.807,0.842,and 0.826 for overall survival and 0.816,0.835,and 0.841 for cancer-specific survival.The internal and external validation cohorts indicated good consistency of the nomogram.CONCLUSION The dynamic nomogram offers robust predictive efficacy for the overall and cancer-specific survival of ampullary adenocarcinoma.展开更多
Background:To investigate adverse event(AE)signals associated with six proton pump inhibitors(PPIs),enhance drug labeling information,and provide guidance for their safe clinical use.Methods:Adverse reaction data for ...Background:To investigate adverse event(AE)signals associated with six proton pump inhibitors(PPIs),enhance drug labeling information,and provide guidance for their safe clinical use.Methods:Adverse reaction data for musculoskeletal and connective tissue disorders related to six PPI formulations—omeprazole,pantoprazole,lansoprazole,esomeprazole,rabeprazole,and dexlansoprazole—from Q12004 to Q42023 were collected from the FDA Adverse Event Reporting System(FAERS).Signal detection was performed using the Reporting Odds Ratio(ROR),Proportional Reporting Ratio(PRR),Bayesian Confidence Propagation Neural Network(BCPNN),and Empirical Bayesian Geometric Mean(EBGM).Data processing and statistical analysis were conducted using R Studio 4.40.Results:A total of 6,635,3,853,1,792,15,731,483,and 534 adverse events were identified for the six PPIs,respectively.The four algorithms(ROR,PRR,BCPNN,and EBGM)generated 17,19,8,27,5,and 2 positive signals.Notably,signals for renal osteodystrophy and osteoporosis were more frequent,with stronger signals for lumbar flexion syndrome and renal osteodystrophy.Conclusion:Patients with chronic kidney disease,a high risk of osteoporosis and fractures,or those using statins should select PPIs with a lower risk of adverse musculoskeletal and connective tissue reactions to minimize these adverse effects and ensure standardized clinical use of PPIs.展开更多
A distinctive feature of scholarly communities today is exploring topics and concepts in interdisciplinary and international contexts. This observation is increasingly apparent and visible in advancing our thinking an...A distinctive feature of scholarly communities today is exploring topics and concepts in interdisciplinary and international contexts. This observation is increasingly apparent and visible in advancing our thinking and policies related to human/environmental worlds at local, regional, and global scales. Maps are an important part of these innovative and ongoing research approaches. In this context, we consider urban forests a topic meriting more attention of scholars studying the geographic and environmental intersections of the natural sciences with the social sciences and humanities. We construct two innovative knowledge bases, one a conceptual framework based on major themes and concepts related to mapping urban forests using key words of the first 100 results of a Google Scholar query and a second using the number of Google Scholar hyperlinks about mapping urban forests in 244 capital cities. We discovered that the constructed world maps reveal vast global unevenness in our knowledge about urban forests in hyperlink numbers and ratios, results that merit further attention by disciplinary, international and interdisciplinary scholarly communities.展开更多
The characteristic databases in China face issues such as narrow resource coverage,low levels of standardization and normalization,and limited data sharing.To address these challenges,this paper proposes the concept o...The characteristic databases in China face issues such as narrow resource coverage,low levels of standardization and normalization,and limited data sharing.To address these challenges,this paper proposes the concept of characteristic databases alliance,using marine characteristic databases as a case for feasibility analysis and discussion.The paper outlines the development path for such alliances and offers recommendations for future growth,aiming to establish a collaborative platform for the development of characteristic databases.展开更多
Objectives:Electronic health records(EHRs)offer valuable real-world data(RWD)for Chinese medicine research.However,significant methodological challenges remain in developing integrative Chinese-Western medicine(ICWM)d...Objectives:Electronic health records(EHRs)offer valuable real-world data(RWD)for Chinese medicine research.However,significant methodological challenges remain in developing integrative Chinese-Western medicine(ICWM)databases.This study aims to establish a best-practice methodological framework,referred to as BRIDGE,to guide the construction of ICWM databases using EHRs.Methods:We developed the methodological framework through a comprehensive process,including systematic literature review,synthesis of empirical experiences,thematic expert discussions,and consultation with an external panel to reach consensus.Results:The BRIDGE framework outlines 6 core components for ICWM-EHR database development:Overall design,database architecture,data extraction and linkage,data governance,data verification,and data quality evaluation.Key data elements include variables related to study population,treatment or exposure,outcomes,and confounders.These databases support various research applications,particularly in evaluating the effectiveness and safety of integrative therapies.To demonstrate its practical value,we developed an ICWM-EHR database on women’s reproductive lifespan,encompassing 2,064,482 patients.This database captures women’s health conditions across the life course,from reproductive age to older adulthood.Conclusions:The BRIDGE methodological framework provides a standardized approach to building high-quality ICWM-EHR databases.It offers a unique opportunity to strengthen the methodological rigor and real-world relevance of Chinese medicine research in integrated healthcare settings.展开更多
The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by the following famous databases: CA, CABI, CSA, EBSCO, UPD, AGRIS, EA, Chinese Science and Technology Periodica...The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by the following famous databases: CA, CABI, CSA, EBSCO, UPD, AGRIS, EA, Chinese Science and Technology Periodical Database, and CNKI, as well as Library of Congress, United States.展开更多
The journal of Meteorological and Environmental Research[ISSN:2152-3940]has been included and stored by the following famous databases:CA,CABI,CSA,EBSCO,UPD,AGRIS,EA,Chinese Science and Technology Periodical Database,...The journal of Meteorological and Environmental Research[ISSN:2152-3940]has been included and stored by the following famous databases:CA,CABI,CSA,EBSCO,UPD,AGRIS,EA,Chinese Science and Technology Periodical Database,and CNKI,as well as Library of Congress,United States.展开更多
The journal of Meteorological and Environmental Research[ISSN:2152-3940]has been included and stored by the following famous databases:CA,CABI,CSA,EBSCO,UPD,AGRIS,EA,Chinese Science and Technology Periodical Database,...The journal of Meteorological and Environmental Research[ISSN:2152-3940]has been included and stored by the following famous databases:CA,CABI,CSA,EBSCO,UPD,AGRIS,EA,Chinese Science and Technology Periodical Database,and CNKI,as well as Library of Congress,United States.展开更多
This paper explores the evolving landscape of digital resources in Greek epigraphy.A selection of digital projects is examined for its structure,accessibility,and scholarly utility,with a critical focus on completenes...This paper explores the evolving landscape of digital resources in Greek epigraphy.A selection of digital projects is examined for its structure,accessibility,and scholarly utility,with a critical focus on completeness,editorial policy,and economic sustainability.The analysis reveals tensions between openaccess ideals and the realities of commercial publishing,as well as challenges posed by short-term funding and limited project scopes.The paper also considers the integration of artificial intelligence tools,notably Ithaca,assessing their potential and current limitations.Emphasis is placed on the pedagogical impact of digital resources,showing how they empower a new generation of students and democratize access to source material.Ultimately,the study underscores the necessity of balancing innovation with scholarly rigor,advocating for ongoing critical reflection to ensure the meaningful development of digital epigraphy in both research and education.展开更多
The kagome lattice,characterized by a hexagonal arrangement of corner-sharing equilateral triangles,has garnered significant attention as a fascinating quantum material system that hosts exotic magnetic and electronic...The kagome lattice,characterized by a hexagonal arrangement of corner-sharing equilateral triangles,has garnered significant attention as a fascinating quantum material system that hosts exotic magnetic and electronic properties.The identification and characterization of this class of materials are critical for advancing our understanding of their role in emergent phenomena such as superconductivity.In this study,we developed a high-throughput screening framework for the systematic identification and classification of superconducting materials with kagome lattices,integrating them into established materials databases.Leveraging the Materials Project(MP)database and the MDR Super Con dataset,we analyzed over 150000 inorganic compounds and cross-referenced 26000 known superconductors.Using geometry-based structural modeling and experimental validation,we identified 129 kagome superconductors belonging to 17 distinct structural families,many of which had not previously been recognized as kagome systems.The materials are further classified into three categories in terms of topological flat bands,clean band structures,and coexisting magnetic or charge density wave(CDW)orderings.Based on these results,we established a database comprising 129 kagome superconductors,including the detailed crystallographic,electronic,and superconducting properties of these materials.展开更多
基金National Key Research and Development Program of China(2021YFB3500501)。
文摘Commercial phosphor-converted white LEDs(pc-WLEDs)face two inherent limitations,namely blue light hazard and low color rendering index,due to the use of blue LEDs as excitation source.To address these challenges,violet LEDs are proposed as an alternative solution.Currently,phosphors that can be efficiently excited by violet light(with wavelengths from 400 to 420 nm)remain under development still.In this study,we utilize large language models to construct a comprehensive database of Eu^(2+)and Ce^(3+)doped phosphors for discovering novel violet-excited phosphors.A total of 822 phosphor data entries,including elemental compositions,crystal structures and excitation/emission wavelengths,have been extracted and validated from 9551 research papers.Compared with Ce^(3+)doped phosphors,the Eu^(2+)are in general more suited for violet-excited phosphors,as well as red-emitting phosphors.In particular,Eu^(2+)doped nitrides and sulfides are worth of exploration for violet-excited phosphors.This database is expected to be useful in the future development of phosphors for pc-WLEDs based on artificial intelligence methods.The datasets in this article are listed in Science Data Bank at http://doi.org/10.57760/sciencedb.34314.
基金Intramural Project of The First Affiliated Hospital of Guangxi University of Chinese Medicine(2018QN008).
文摘Background:The purpose of this study was to analyze and classify adverse drug events(ADEs)related to ceftazidime/avibactam reported in the Food and Drug Administration Adverse Event Reporting System(FAERS)database and to evaluate their potential safety signals since the drug’s market introduction.Methods:This analysis systematically extracted and filtered FAERS data for ceftazidime/avibactam from its market launch in 2015 to the last quarter of 2024,utilizing the Medical Dictionary for Regulatory Activities(MedDRA)terminology for ADE recoding.The analysis employed the reporting odds ratio(ROR)method to assess the strength of ADE signals and to identify significant diseases associated with infections,the hepatobiliary system,the urinary system,and the nervous system.Results:A review of 540 adverse reaction reports revealed significant signals of adverse effects related to infections,hepatobiliary disorders,urinary system issues,and neurological impairments,including pathogen resistance,liver and kidney function impairment,encephalopathy,thrombocytopenia,and toxic epidermal necrolysis.However,these issues require further clinical attention.Conclusion:Ceftazidime/avibactam is associated with a range of adverse reactions,necessitating enhanced clinical monitoring,particularly in patients with underlying liver or kidney dysfunction.Continuous risk assessment and vigilant monitoring are critical for its clinical use.However,this study is limited by inherent reporting biases and confounders associated with the spontaneous reporting database(FAERS).Future research should validate these signals through prospective cohort and mechanistic studies and explore personalized risk management strategies for high-risk populations.
基金Natural Science Foundation of China under Grant No.52178449,the Beijing Natural Science Foundation under Grant No.8234060the Innovation Center of Beijing Association for Science and Technology。
文摘This study proposes a new post-tensioned precast bridge column(PT-PBC)with a socket connection.Compared to conventional PBCs connected by PT tendons,the combination of the PT tendons with the socket connection can avoid tensioning the PT tendons on site,which further accelerates construction speed while improving construction quality and safety.In addition,compared to conventional PBCs with a socket connection,a rocking interface can avoid the formation of a plastic hinge in a column,which greatly alleviates seismic damage to that area.One specimen for quasi-static testing is used to validate the feasibility of this connection type.Subsequently,finite element models(FEM)are established to systematically predict the responses of the proposed columns under lateral cyclic loading.The accuracy of the FEM is verified through quasistatic testing.Next,the influences of the key design parameters of the PT-PBC,including the area ratio and prestress level of the PT tendons,the area ratio of energy dissipation(ED)steel rebars,and the total axial compression ratio on the seismic performances of PT-PBC are systematically investigated.The use of shape memory alloy(SMA)rods as energy dissipation devices and their performances also are investigated.The results show that increasing the area ratio and prestress level of PT tendons has an overall positive impact on the self-centering capacity of the column.The prestress level of PT tendons should be kept between 35%and 55%,depending on different conditions.The total compression axial ratio of the columns should be maintained between 0.3 and 0.4.Both ED steel rebars and SMA rods can boost the column’s energy dissipation capacity,while SMA rods can reduce residual deformation due to their inherent mechanical properties.
基金supported by the“Regional Innovation System&Education(RISE)”through the Seoul RISE Center,funded by the Ministry of Education(MOE)and the Seoul Metropolitan Government.(2025-RISE-01-005-07).
文摘Background:Social connection is widely recognized as a protective determinant of health,yet its direct and indirect effects on mental health remain underexplored.This study examines the relationship between social connection and mental health,focusing on the mediating role of quality of life(QoL)and the moderating effect of regional differences.Methods:We analyzed data from the 2019 Korean Community Health Survey,comprising 229,099 adults.Mental health was assessed through validated measures of depressive symptoms and psychological well-being.Social connection was measured using indicators of interpersonal ties and community participation,and QoL was assessed via self-reported health-related satisfaction across major life domains.Analytical procedures included mediation modeling and subgroup analyses by region,with significance levels set at p<0.05.Results:The results indicate that social connections are significantly associated with lower stress levels and reduced depressive symptoms,with QoL playing a critical mediating role.Notably,the indirect effect of social connection on mental health via QoL is stronger in rural areas compared to urban regions,highlighting the importance of social cohesion and community support in mental well-being.Among 203,567 adults,greater social participation was associated with lower subjective stress(total effect=−0.052,p<0.001)and fewer depressive symptoms(PHQ-9 total effect=−0.308,p<0.001).QoL significantly mediated these associations,with the strongest indirect pathways observed through usual activities(19.2%for stress;27.6%for depression)and mobility(24.4%for depression).Regional analysis showed stronger mediation in rural areas(up to 26.8%for stress and 32.6%for depression)than in urban areas(8–16%and 14.9–23%).Direct effects remained significant,indicating partial mediation.These findings highlight that social participation enhances mental health directly and indirectly through QoL,particularly in rural contexts.Conclusions:Social connection contributes to better mental health both directly and indirectly through improved QoL,with stronger effects observed in rural communities.These findings highlight the importance of fostering social cohesion and enhancing life quality as strategies for improving population mental health.Policy interventions should adopt context-sensitive approaches that account for regional differences in social resources and service availability.
基金funded by Science and Technology Innovation Project grant No.ZZKY20222304.
文摘Aiming at the problem of potential information noise introduced during the generation of ghost feature maps in GhostNet,this paper proposes a novel lightweight neural network model called ResghostNet.This model constructs the Resghost Module by combining residual connections and Adaptive-SE Blocks,which enhances the quality of generated feature maps through direct propagation of original input information and selection of important channels before cheap operations.Specifically,ResghostNet introduces residual connections on the basis of the Ghost Module to optimize the information flow,and designs a weight self-attention mechanism combined with SE blocks to enhance feature expression capabilities in cheap operations.Experimental results on the ImageNet dataset show that,compared to GhostNet,ResghostNet achieves higher accuracy while reducing the number of parameters by 52%.Although the computational complexity increases,by optimizing the usage strategy of GPU cachememory,themodel’s inference speed becomes faster.The ResghostNet is optimized in terms of classification accuracy and the number of model parameters,and shows great potential in edge computing devices.
基金Project supported by Quantum Science and Technology–National Science and Technology Major Project(Grant No.2024ZD0301000)the National Natural Science Foundation of China(Grant No.12305031)+1 种基金the Hangzhou Joint Fund of the Natural Science Foundation of Zhejiang Province,China(Grant No.LHZSD24A050001)the Science Foundation of Zhejiang Sci-Tech University(Grant Nos.23062088Y and 23062153-Y)。
文摘The Wilczek–Zee connection(WZC)is a key concept in the study of topology of quantum systems.Here,we introduce the double Wilczek–Zee connection(DWZC)which naturally appears in the pure-state quantum geometric tensor(QGT),another important concept in the field of quantum geometry.The DWZC is Hermitian with respect to the two integer indices,just like the original Hermitian WZC.Based on the symmetric logarithmic derivative operator,we propose a mixed-state quantum geometric tensor.Using the symmetric properties of the DWZC,we find that the real part of the QGT is connected to the real part of the DWZC and the square of eigenvalue differences of the density matrix,whereas the imaginary part can be given in terms of the imaginary part of the DWZC and the cube of the eigenvalue differences.For density matrices with full rank or no full rank,the QGT can be given in terms of real and imaginary parts of the DWZC.
文摘Yunhe County in Lishui City,southwestern Zhejiang Province,doesn’t have any Disney castles.Instead,it has built bridges to the world with wood.Known as“China’s town of wooden toys,”accounting for about 40 percent of the global wooden toy market,Yunhe’s story began with a small factory established in 1970.Today,it has grown into a distinctive industrial cluster with an annual output value exceeding 8 billion yuan($1.15 billion),exporting products to 82 countries and regions.
文摘Founded in September 2020,the International SparkLink Alliance(iSLA)now has approximately 1,200 members in diverse sectors including terminals,homes,vehicles,manufacturing,transportation,finance and healthcare.The iSLA has established a technical standards system for wireless short-range communication covering full-stack standards such as the end-to-end protocol system.
基金funded by the National Natural Science Foundation of China(No.42220104008)。
文摘Research into metamorphism plays a pivotal role in reconstructing the evolution of continent,particularly through the study of ancient rocks that are highly susceptible to metamorphic alterations due to multiple tectonic activities.In the big data era,the establishment of new data platforms and the application of big data methods have become a focus for metamorphic rocks.Significant progress has been made in creating specialized databases,compiling comprehensive datasets,and utilizing data analytics to address complex scientific questions.However,many existing databases are inadequate in meeting the specific requirements of metamorphic research,resulting from a substantial amount of valuable data remaining uncollected.Therefore,constructing new databases that can cope with the development of the data era is necessary.This article provides an extensive review of existing databases related to metamorphic rocks and discusses data-driven studies in this.Accordingly,several crucial factors that need to be taken into consideration in the establishment of specialized metamorphic databases are identified,aiming to leverage data-driven applications to achieve broader scientific objectives in metamorphic research.
基金Supported by the Appropriate Technology Promotion Program in Chongqing,No.2023jstg005.
文摘BACKGROUND Ampullary adenocarcinoma is a rare malignant tumor of the gastrointestinal tract.Currently,only a few cases have been reported,resulting in limited information on survival.AIM To develop a dynamic nomogram using internal and external validation to predict survival in patients with ampullary adenocarcinoma.METHODS Data were sourced from the surveillance,epidemiology,and end results stat database.The patients in the database were randomized in a 7:3 ratio into training and validation groups.Using Cox regression univariate and multivariate analyses in the training group,we identified independent risk factors for overall survival and cancer-specific survival to develop the nomogram.The nomogram was validated with a cohort of patients from the First Affiliated Hospital of the Army Medical University.RESULTS For overall and cancer-specific survival,12(sex,age,race,lymph node ratio,tumor size,chemotherapy,surgical modality,T stage,tumor differentiation,brain metastasis,lung metastasis,and extension)and 6(age;surveillance,epidemiology,and end results stage;lymph node ratio;chemotherapy;surgical modality;and tumor differentiation)independent risk factors,respectively,were incorporated into the nomogram.The area under the curve values at 1,3,and 5 years,respectively,were 0.807,0.842,and 0.826 for overall survival and 0.816,0.835,and 0.841 for cancer-specific survival.The internal and external validation cohorts indicated good consistency of the nomogram.CONCLUSION The dynamic nomogram offers robust predictive efficacy for the overall and cancer-specific survival of ampullary adenocarcinoma.
文摘Background:To investigate adverse event(AE)signals associated with six proton pump inhibitors(PPIs),enhance drug labeling information,and provide guidance for their safe clinical use.Methods:Adverse reaction data for musculoskeletal and connective tissue disorders related to six PPI formulations—omeprazole,pantoprazole,lansoprazole,esomeprazole,rabeprazole,and dexlansoprazole—from Q12004 to Q42023 were collected from the FDA Adverse Event Reporting System(FAERS).Signal detection was performed using the Reporting Odds Ratio(ROR),Proportional Reporting Ratio(PRR),Bayesian Confidence Propagation Neural Network(BCPNN),and Empirical Bayesian Geometric Mean(EBGM).Data processing and statistical analysis were conducted using R Studio 4.40.Results:A total of 6,635,3,853,1,792,15,731,483,and 534 adverse events were identified for the six PPIs,respectively.The four algorithms(ROR,PRR,BCPNN,and EBGM)generated 17,19,8,27,5,and 2 positive signals.Notably,signals for renal osteodystrophy and osteoporosis were more frequent,with stronger signals for lumbar flexion syndrome and renal osteodystrophy.Conclusion:Patients with chronic kidney disease,a high risk of osteoporosis and fractures,or those using statins should select PPIs with a lower risk of adverse musculoskeletal and connective tissue reactions to minimize these adverse effects and ensure standardized clinical use of PPIs.
文摘A distinctive feature of scholarly communities today is exploring topics and concepts in interdisciplinary and international contexts. This observation is increasingly apparent and visible in advancing our thinking and policies related to human/environmental worlds at local, regional, and global scales. Maps are an important part of these innovative and ongoing research approaches. In this context, we consider urban forests a topic meriting more attention of scholars studying the geographic and environmental intersections of the natural sciences with the social sciences and humanities. We construct two innovative knowledge bases, one a conceptual framework based on major themes and concepts related to mapping urban forests using key words of the first 100 results of a Google Scholar query and a second using the number of Google Scholar hyperlinks about mapping urban forests in 244 capital cities. We discovered that the constructed world maps reveal vast global unevenness in our knowledge about urban forests in hyperlink numbers and ratios, results that merit further attention by disciplinary, international and interdisciplinary scholarly communities.
文摘The characteristic databases in China face issues such as narrow resource coverage,low levels of standardization and normalization,and limited data sharing.To address these challenges,this paper proposes the concept of characteristic databases alliance,using marine characteristic databases as a case for feasibility analysis and discussion.The paper outlines the development path for such alliances and offers recommendations for future growth,aiming to establish a collaborative platform for the development of characteristic databases.
基金supported by the National Key Research&Development Program of China(No.2024YFC3505800)the National Natural Science Foundation of China(Nos.82474334,82474335 and 72174132)+3 种基金National Science Fund for Distinguished Young Scholars(No.82225049)the Key Research&Development Projects of Sichuan Provincial Department of Science and Technology(Nos.2024YFFK0174 and 2024YFFK0152)1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(Nos.ZYYC24010 and ZYGD23004)the Special Fund for Traditional Chinese Medicine of Sichuan Provincial Administration of Traditional Chinese Medicine(No.2024zd023).
文摘Objectives:Electronic health records(EHRs)offer valuable real-world data(RWD)for Chinese medicine research.However,significant methodological challenges remain in developing integrative Chinese-Western medicine(ICWM)databases.This study aims to establish a best-practice methodological framework,referred to as BRIDGE,to guide the construction of ICWM databases using EHRs.Methods:We developed the methodological framework through a comprehensive process,including systematic literature review,synthesis of empirical experiences,thematic expert discussions,and consultation with an external panel to reach consensus.Results:The BRIDGE framework outlines 6 core components for ICWM-EHR database development:Overall design,database architecture,data extraction and linkage,data governance,data verification,and data quality evaluation.Key data elements include variables related to study population,treatment or exposure,outcomes,and confounders.These databases support various research applications,particularly in evaluating the effectiveness and safety of integrative therapies.To demonstrate its practical value,we developed an ICWM-EHR database on women’s reproductive lifespan,encompassing 2,064,482 patients.This database captures women’s health conditions across the life course,from reproductive age to older adulthood.Conclusions:The BRIDGE methodological framework provides a standardized approach to building high-quality ICWM-EHR databases.It offers a unique opportunity to strengthen the methodological rigor and real-world relevance of Chinese medicine research in integrated healthcare settings.
文摘The journal of Meteorological and Environmental Research [ISSN: 2152-3940] has been included and stored by the following famous databases: CA, CABI, CSA, EBSCO, UPD, AGRIS, EA, Chinese Science and Technology Periodical Database, and CNKI, as well as Library of Congress, United States.
文摘The journal of Meteorological and Environmental Research[ISSN:2152-3940]has been included and stored by the following famous databases:CA,CABI,CSA,EBSCO,UPD,AGRIS,EA,Chinese Science and Technology Periodical Database,and CNKI,as well as Library of Congress,United States.
文摘The journal of Meteorological and Environmental Research[ISSN:2152-3940]has been included and stored by the following famous databases:CA,CABI,CSA,EBSCO,UPD,AGRIS,EA,Chinese Science and Technology Periodical Database,and CNKI,as well as Library of Congress,United States.
文摘This paper explores the evolving landscape of digital resources in Greek epigraphy.A selection of digital projects is examined for its structure,accessibility,and scholarly utility,with a critical focus on completeness,editorial policy,and economic sustainability.The analysis reveals tensions between openaccess ideals and the realities of commercial publishing,as well as challenges posed by short-term funding and limited project scopes.The paper also considers the integration of artificial intelligence tools,notably Ithaca,assessing their potential and current limitations.Emphasis is placed on the pedagogical impact of digital resources,showing how they empower a new generation of students and democratize access to source material.Ultimately,the study underscores the necessity of balancing innovation with scholarly rigor,advocating for ongoing critical reflection to ensure the meaningful development of digital epigraphy in both research and education.
基金supported by the National Key Research and Development Program of China(Grant No.2018YFE0202600)the National Natural Science Foundation of China(Grant No.52272268)+3 种基金the Key Research Program of Frontier SciencesCAS(Grant No.QYZDJ-SSWSLH013)the Informatization Plan of Chinese Academy of Sciences(Grant No.CAS-WX2021SF-0102)the Youth Innovation Promotion Association of CAS(Grant No.2019005)。
文摘The kagome lattice,characterized by a hexagonal arrangement of corner-sharing equilateral triangles,has garnered significant attention as a fascinating quantum material system that hosts exotic magnetic and electronic properties.The identification and characterization of this class of materials are critical for advancing our understanding of their role in emergent phenomena such as superconductivity.In this study,we developed a high-throughput screening framework for the systematic identification and classification of superconducting materials with kagome lattices,integrating them into established materials databases.Leveraging the Materials Project(MP)database and the MDR Super Con dataset,we analyzed over 150000 inorganic compounds and cross-referenced 26000 known superconductors.Using geometry-based structural modeling and experimental validation,we identified 129 kagome superconductors belonging to 17 distinct structural families,many of which had not previously been recognized as kagome systems.The materials are further classified into three categories in terms of topological flat bands,clean band structures,and coexisting magnetic or charge density wave(CDW)orderings.Based on these results,we established a database comprising 129 kagome superconductors,including the detailed crystallographic,electronic,and superconducting properties of these materials.
