With the gradual acceleration of information construction in colleges and universities,digital campus and smart campus have gradually become important means for colleges and universities to scientifically manage the c...With the gradual acceleration of information construction in colleges and universities,digital campus and smart campus have gradually become important means for colleges and universities to scientifically manage the campus.They have been applied to teaching,scientific research,student management,and other fields,improving the quality and efficiency of management.This paper mainly studies the intelligent educational administration management system based on data mining technology.Firstly,this paper introduces the application process of data mining technology,and builds an intelligent educational administration management system based on data mining technology.Then,this paper optimizes the application of the Apriori algorithm in educational administration management through transaction compression and frequent sampling.Compared with the traditional Apriori algorithm,the optimized Apriori algorithm in this paper has a shorter execution time under the same minimum support.展开更多
In conjunction with association rules for data mining, the connections between testing indices and strong and weak association rules were determined, and new derivative rules were obtained by further reasoning. Associ...In conjunction with association rules for data mining, the connections between testing indices and strong and weak association rules were determined, and new derivative rules were obtained by further reasoning. Association rules were used to analyze correlation and check consistency between indices. This study shows that the judgment obtained by weak association rules or non-association rules is more accurate and more credible than that obtained by strong association rules. When the testing grades of two indices in the weak association rules are inconsistent, the testing grades of indices are more likely to be erroneous, and the mistakes are often caused by human factors. Clustering data mining technology was used to analyze the reliability of a diagnosis, or to perform health diagnosis directly. Analysis showed that the clustering results are related to the indices selected, and that if the indices selected are more significant, the characteristics of clustering results are also more significant, and the analysis or diagnosis is more credible. The indices and diagnosis analysis function produced by this study provide a necessary theoretical foundation and new ideas for the development of hydraulic metal structure health diagnosis technology.展开更多
This article explores the design of a wireless fire alarm system supported by advanced data fusion technology.It includes discussions on the basic design ideas of the wireless fire alarm system,hardware design analysi...This article explores the design of a wireless fire alarm system supported by advanced data fusion technology.It includes discussions on the basic design ideas of the wireless fire alarm system,hardware design analysis,software design analysis,and simulation analysis,all supported by data fusion technology.Hopefully,this analysis can provide some reference for the rational application of data fusion technology to meet the actual design and application requirements of the system.展开更多
Objective:To explore the core acupoints and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy,and,further to analyze the characteristics of the prescription of acupunc...Objective:To explore the core acupoints and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy,and,further to analyze the characteristics of the prescription of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy.Methods:Relevant clinical studies in seven databases were searched systematically from database inception to 1 st October 2020.Based on data mining techniques,the core acupoints,characteristics and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy were analyzed comprehensively.Statistics collected and analysis of acupoint selection included the frequency of usage of acupoints,the meridian of acupoints,the location of acupoints and the combination of acupoints.Cluster and association analysis were performed utilizing Excel 13.0 and SPSS 26.0.Results:In the 36 studies included,the most frequently adopted acupoint was Sānyīnjiāo(三阴交 SP6);the most frequently adopted meridian was the foot-taiyin spleen meridian;the most frequently involved location was the lower limbs;and the most frequently adopted combination of acupoints was SP6 and Zhōngjí(中极CV 3).Cluster analysis showed that the acupoints could be divided into three categories:the first group comprised SP6 alone;the second group included CV3,Guānyuán(关元CV4),Yīnlíngquán(阴陵泉SP9) and Zúsānlǐ(足三里ST36);and the third group included Pángguāngshū(膀胱俞BL28),Chéngshān(承山BL57),Tàichōng(太冲LR3),Zhìbiān(秩边 BL54),Tàixī(太溪KI6),Hégǔ(合谷 LI4),Xuèhǎi(血海SP10),Qìhǎi(气海CV6) and Shǔidào(水道ST28).Conclusion:It was found that acupuncture therapy for postoperative urinary retention after hemorrhoidectomy mainly follows the four characteristic rules:the selection of acupoints following the meridian,selection of acupoints at local points,selection of acupoints at distal points and selection of acupoints according to special symptoms.展开更多
With the economic development and the popularity of application of electronic computer, electronic commerce has rapid development. More and more commerce and key business has been carried on the lnternet because Inter...With the economic development and the popularity of application of electronic computer, electronic commerce has rapid development. More and more commerce and key business has been carried on the lnternet because Internet has the features of interaction, openness, sharing and so on. However, during the daily commerce, people worry about the security of the network system. So a new technology which can detect the unusual behavior in time has been invented in order to protect the security of network system. The system of intrusion detection needs a lot of new technology to protect the data of the network system. The application of data mining technology in the system of intrusion detection can provide a better assistant to the users to analyze the data and improve the accuracy of the checking system.展开更多
In order to accurately identify the characters associated with consumption behavior of apparel online shopping, a typical B/ C clothing enterprise in China was chosen. The target experimental database containing 2000 ...In order to accurately identify the characters associated with consumption behavior of apparel online shopping, a typical B/ C clothing enterprise in China was chosen. The target experimental database containing 2000 data records was obtained based on web service logs of sample enterprise. By means of clustering algorithm of Clementine Data Mining Software, K-means model was set up and 8 clusters of consumer were concluded. Meanwhile, the implicit information existed in consumer's characters and preferences for clothing was found. At last, 31 valuable association rules among casual wear, formal wear, and tie-in products were explored by using web analysis and Aprior algorithm. This finding will help to better understand the nature of online apparel consumption behavior and make a good progress in personalization and intelligent recommendation strategies.展开更多
Distributed Data Mining is expected to discover preciously unknown, implicit and valuable information from massive data set inherently distributed over a network. In recent years several approaches to distributed data...Distributed Data Mining is expected to discover preciously unknown, implicit and valuable information from massive data set inherently distributed over a network. In recent years several approaches to distributed data mining have been developed, but only a few of them make use of intelligent agents. This paper provides the reason for applying Multi-Agent Technology in Distributed Data Mining and presents a Distributed Data Mining System based on Multi-Agent Technology that deals with heterogeneity in such environment. Based on the advantages of both the CS model and agent-based model, the system is being able to address the specific concern of increasing scalability and enhancing performance.展开更多
The publisher regrets that the article type for this publication was incorrectly labeled as a Research Article.The correct designation should be Review Article.This correction does not affect the content or conclusion...The publisher regrets that the article type for this publication was incorrectly labeled as a Research Article.The correct designation should be Review Article.This correction does not affect the content or conclusions of the article.The publisher apologizes for any inconvenience caused.展开更多
Computer simulation for materials processing needs a huge database containing a great deal of various physical properties of materials. In order to employ the accumulated large data on materials heat treatment in the ...Computer simulation for materials processing needs a huge database containing a great deal of various physical properties of materials. In order to employ the accumulated large data on materials heat treatment in the past years, it is significant to develop an intelligent database system. Based on the data mining technology for data analysis, an intelligent database web tool system of computer simulation for heat treatment process named as IndBASEweb-HT was built up. The architecture and the arithmetic of this system as well as its application were introduced.展开更多
In this study,we employed a combination of genome mining and heteronuclear single quantum coherence(HSQC)-based small molecule accurate recognition technology(SMART)technology to search for fernane-type triterpenoids....In this study,we employed a combination of genome mining and heteronuclear single quantum coherence(HSQC)-based small molecule accurate recognition technology(SMART)technology to search for fernane-type triterpenoids.Initially,potential endophytic fungi were identified through genome mining.Subsequently,fine fractions containing various fernane-type triterpenoids were selected using HSQC data collection and SMART prediction.These triterpenoids were then obtained through targeted isolation and identification.Finally,their antifungal activity was evaluated.As a result,three fernane-type triterpenoids,including two novel compounds,along with two new sesquiterpenes and four known compounds were isolated from one potential strain,Diaporthe discoidispora.Their structures were elucidated through analysis of high-resolution electrospray ionization mass spectrometry(HR-ESI-MS)and nuclear magnetic resonance(NMR)spectroscopic data.The absolute configurations were determined using single-crystal X-ray diffraction analysis and electron capture detector(ECD)analysis.Compound 3 exhibited moderate antifungal activity against Candida albicans CMCC 98001 and Aspergillus niger.展开更多
In the present study,data mining and network pharmacology were utilized to explore the principles and mechanisms of traditional Chinese medicine(TCM)in treating acute appendicitis.The goal was to provide a scientific ...In the present study,data mining and network pharmacology were utilized to explore the principles and mechanisms of traditional Chinese medicine(TCM)in treating acute appendicitis.The goal was to provide a scientific basis for clinical treatment and further research on this disease.First,we searched the National Patent Database for Chinese herbal compound prescriptions used to treat acute appendicitis.We then applied frequency analysis,character and taste meridian analysis,association rule analysis,and hierarchical cluster analysis to identify the patterns of TCM treatment for acute appendicitis,selecting key combinations of Chinese medicines.Next,we screened the main active components of these key TCM based on quality markers.Using databases such as SwissTargetPrediction,SymMap,ETCM,and STRING,we analyzed the pharmacological mechanisms of these key TCM in treating acute appendicitis.Key active components and targets were further verified through molecular docking.We identified a total of 129 patents involving 316 Chinese medicines,with 24 being frequently used.The results indicated that most Chinese herbs used for acute appendicitis were heat-clearing drugs,blood-activating and stasis-removing drugs,and purging drugs.The primary active ingredients of the Rhubarb-cortex moutan-flos lonicerae combination for treating acute appendicitis included Emodin,Paeonol,Physcion,Chlorogenic acid,Chrysophanol,Rhein acid,and Aloe-emodin.These ingredients targeted key proteins such as ALB,TP53,BCL2,STAT3,IL-6,and TNF,and were involved in cellular responses to lipopolysaccharides,cell composition,and various cytokine-mediated biological processes.They also interacted with signaling pathways like AGE-RAGE,TNF,IL-17,and FoxO.Based on patent data,this study analyzed medication patterns in the treatment of acute appendicitis,discussed the possible mechanisms of key TCM combinations,and provided a scientific basis and new perspectives for the diagnosis and treatment of the disease.展开更多
This article focuses on the current computer monitoring and control as the research direction,studying the application strategies of artificial intelligence and big data technology in this field.It includes an introdu...This article focuses on the current computer monitoring and control as the research direction,studying the application strategies of artificial intelligence and big data technology in this field.It includes an introduction to artificial intelligence and big data technology,the application strategies of artificial intelligence and big data technology in computer hardware,software,and network monitoring,as well as the application strategies of artificial intelligence and big data technology in computer process,access,and network control.This analysis aims to serve as a reference for the application of artificial intelligence and big data technology in computer monitoring and control,ultimately enhancing the security of computer systems.展开更多
In the era of big data,data has gradually become an important asset of enterprises,and the application of big data technology has gradually become the key to the optimization of enterprise marketing management mode.En...In the era of big data,data has gradually become an important asset of enterprises,and the application of big data technology has gradually become the key to the optimization of enterprise marketing management mode.Enterprises take the initiative to meet the development trend of the times,rely on big data technology to effectively process and analyze data,innovate decision-making methods and operation models,and achieve efficient marketing and fine management,which is an important way to improve their market competitiveness.Therefore,the author first analyzes the empowering role of big data technology on enterprise marketing management,and then discusses the difficulties faced by enterprise marketing management in the era of big data,and finally puts forward targeted improvement strategies,aiming to provide a reference for enterprises to innovate and change the marketing management mode.展开更多
Objective To explore the optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade using data mining.Methods ...Objective To explore the optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade using data mining.Methods Clinical studies of abdominal obesity treated with acupuncture and moxibustion,collected in the past 10 years,were searched from China Biology Medicine disc(CBMdisc),China National knowledge infrastructure(CNKI),Wanfang,China Science and Technology Journal Database(VIP),Pubmed,Embase,Google Scholar,Web of Science,(The Cumulative Index to Nursing and Allied Health Literature)CINAHL,Psyclnfo and Scopus,dated from March 1,2013 to March 31,2023.Using IBM SPSS Modeler 18.0 and other software,the frequency analysis,association-rules analysis and cluster analysis were conducted on interventions,traditional Chinese medicine(TCM)patterns,use frequency of acupoint,meridian attribution of acupoint,acupoint location,etc.Results A total of 55 articles were included,with 102 prescriptions and 71 acupoints involved.The top 3 interventions were acupoint embedding method,simple electroacupuncture and simple filiform needling.Seventeen patterns/syndromes of TCM differentiation were collected,dominated by spleen deficiency and damp blockage,spleen and kidney yang deficiency and heat accumulation in stomach and intestines.The acupoints in clinical practice were mostly at the foot-yangming stomach meridian,the conception vessel and the foot-taiyin spleen meridian,and located at the abdominal region.The top 5 acupoints of high frequency were Tianshu(ST25),Zhongwan(CV12),Daheng(SP15),Zusanli(ST36),Huaroumen(ST24)and Daimai(GB26).The specific points of the high frequency were the crossing points and front-mu points,of which,ST25 and CV12 were the most prominent.After association-rules analysis on the high-frequency acupoints,20 groups of associated acupoints were obtained,in which,the core acupoints included ST25,CV12,SP15 and ST36.Conclusion In recent 10 years,abdominal obesity is treated by the acupoints of foot-yangming stomach meridian,the conception vessel and the foot-taiyin spleen meridian.Compared with the regimen for simple obesity,the acupoints at the abdominal region are specially selected in treatment of abdominal obesity,such as ST25,CV12,SP15 and ST36.Supplementary acupoints are selected based on syndrome differentiation to simultaneously address both the disease manifestations and root causes.展开更多
Objective:To explore the core acupuncture acupoints and pattern-adapted acupoint combination rules for autism spectrum disorder(ASD)complicated with sleep disorder using clinical data mining technology.Methods:A retro...Objective:To explore the core acupuncture acupoints and pattern-adapted acupoint combination rules for autism spectrum disorder(ASD)complicated with sleep disorder using clinical data mining technology.Methods:A retrospective analysis was conducted on the diagnosis and treatment data of 104 children with ASD complicated with sleep disorder admitted to Xi’an Traditional Chinese Medicine(TCM)Encephalopathy Hospital from January 2022 to December 2024.Cross-pattern main acupoints were screened via frequency statistics,chi-square test,and factor analysis;pattern-specific auxiliary acupoints were extracted by combining multiple correspondence analysis,cluster analysis,and association rule mining.Results:Ten cross-pattern main acupoints(Baihui,Sishenzhen,Language Area 1,Language Area 2,Neiguan,Shenmen,Yongquan,Xuanzhong)were identified,and acupoint combination schemes for four major TCM patterns(Hyperactivity of Liver and Heart Fire,Deficiency of Kidney Essence,Deficiency of Both Heart and Spleen,Hyperactivity of Liver with Spleen Deficiency)were established.Conclusion:Acupuncture treatment should follow the principle of“regulating spirit and calming the brain as the root,and dredging collaterals based on pattern differentiation as the branch”.The synergy between main and auxiliary acupoints can accurately regulate the disease,providing a basis for precise clinical treatment.展开更多
With the rapid development of the Internet and e-commerce,e-commerce platforms have accumulated huge amounts of user behavior data.The emergence of big data technology provides a powerful means for in-depth analysis o...With the rapid development of the Internet and e-commerce,e-commerce platforms have accumulated huge amounts of user behavior data.The emergence of big data technology provides a powerful means for in-depth analysis of these data and insight into user behavior patterns and preferences.This paper elaborates on the application of big data technology in the analysis of user behavior on e-commerce platforms,including the technical methods of data collection,storage,processing and analysis,as well as the specific applications in the construction of user profiles,precision marketing,personalized recommendation,user retention and churn analysis,etc.,and discusses the challenges and countermeasures faced in the application.Through the study of actual cases,it demonstrates the remarkable effectiveness of big data technology in enhancing the competitiveness of e-commerce platforms and user experience.展开更多
Computer science and technology play an important role in people’s lives and work,especially in the era of big data.The application of computer science and technology is conducive to improving people’s production an...Computer science and technology play an important role in people’s lives and work,especially in the era of big data.The application of computer science and technology is conducive to improving people’s production and living standards and provides a strong impetus for China’s social and economic development.Therefore,this paper analyzes the application of computer science and technology in the context of big data and puts forward new trends and requirements for its future development,aiming to provide some references for the computer science and technology industry.展开更多
With the advancement of the rural revitalization strategy,preventing poverty recurrence among previously impoverished populations has become a crucial social concern.The application of big data technology in poverty r...With the advancement of the rural revitalization strategy,preventing poverty recurrence among previously impoverished populations has become a crucial social concern.The application of big data technology in poverty recurrence monitoring and agricultural product sales systems can effectively enhance precise identification and early warning capabilities,promoting the sustainable development of rural economies.This paper explores the application of big data technology in poverty recurrence monitoring,analyzes its innovative integration with agricultural product sales systems,and proposes an intelligent monitoring and sales platform model based on big data,aiming to provide a reference for relevant policy formulation.展开更多
With the rapid development of computer network,the society has entered the information and digital era,it plays an important role in speeding up the pace of social development and providing more convenient services fo...With the rapid development of computer network,the society has entered the information and digital era,it plays an important role in speeding up the pace of social development and providing more convenient services for people.However, the security problem of computer network is becoming more and more serious. All kinds of network viruses pose a great threat to the security of computer network.As the most advanced data processing technology currently, data mining technology can effectively resist the invasion of network virus to computer system,and plays an important role in improving the security of the computer network.This paper starts with the concept of data mining technology and the characteristics of computer network virus,and makes an in-depth analysis on the specific application of data mining technology in the computer network virus defense.展开更多
This paper makes a brief description of the definition and methods of data mining.It describes the characteristics of agricultural data(value delivery,specialization,spatio-temporal bidimensionality)and the status of ...This paper makes a brief description of the definition and methods of data mining.It describes the characteristics of agricultural data(value delivery,specialization,spatio-temporal bidimensionality)and the status of application of data mining technology in agriculture.展开更多
文摘With the gradual acceleration of information construction in colleges and universities,digital campus and smart campus have gradually become important means for colleges and universities to scientifically manage the campus.They have been applied to teaching,scientific research,student management,and other fields,improving the quality and efficiency of management.This paper mainly studies the intelligent educational administration management system based on data mining technology.Firstly,this paper introduces the application process of data mining technology,and builds an intelligent educational administration management system based on data mining technology.Then,this paper optimizes the application of the Apriori algorithm in educational administration management through transaction compression and frequent sampling.Compared with the traditional Apriori algorithm,the optimized Apriori algorithm in this paper has a shorter execution time under the same minimum support.
基金supported by the Key Program of the National Natural Science Foundation of China(Grant No.50539010)the Special Fund for Public Welfare Industry of the Ministry of Water Resources of China(Grant No.200801019)
文摘In conjunction with association rules for data mining, the connections between testing indices and strong and weak association rules were determined, and new derivative rules were obtained by further reasoning. Association rules were used to analyze correlation and check consistency between indices. This study shows that the judgment obtained by weak association rules or non-association rules is more accurate and more credible than that obtained by strong association rules. When the testing grades of two indices in the weak association rules are inconsistent, the testing grades of indices are more likely to be erroneous, and the mistakes are often caused by human factors. Clustering data mining technology was used to analyze the reliability of a diagnosis, or to perform health diagnosis directly. Analysis showed that the clustering results are related to the indices selected, and that if the indices selected are more significant, the characteristics of clustering results are also more significant, and the analysis or diagnosis is more credible. The indices and diagnosis analysis function produced by this study provide a necessary theoretical foundation and new ideas for the development of hydraulic metal structure health diagnosis technology.
基金Chongqing Engineering University Undergraduate Innovation and Entrepreneurship Training Program Project:Wireless Fire Automatic Alarm System(Project No.:CXCY2024017)Chongqing Municipal Education Commission Science and Technology Research Project:Development and Research of Chongqing Wireless Fire Automatic Alarm System(Project No.:KJQN202401906)。
文摘This article explores the design of a wireless fire alarm system supported by advanced data fusion technology.It includes discussions on the basic design ideas of the wireless fire alarm system,hardware design analysis,software design analysis,and simulation analysis,all supported by data fusion technology.Hopefully,this analysis can provide some reference for the rational application of data fusion technology to meet the actual design and application requirements of the system.
文摘Objective:To explore the core acupoints and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy,and,further to analyze the characteristics of the prescription of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy.Methods:Relevant clinical studies in seven databases were searched systematically from database inception to 1 st October 2020.Based on data mining techniques,the core acupoints,characteristics and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy were analyzed comprehensively.Statistics collected and analysis of acupoint selection included the frequency of usage of acupoints,the meridian of acupoints,the location of acupoints and the combination of acupoints.Cluster and association analysis were performed utilizing Excel 13.0 and SPSS 26.0.Results:In the 36 studies included,the most frequently adopted acupoint was Sānyīnjiāo(三阴交 SP6);the most frequently adopted meridian was the foot-taiyin spleen meridian;the most frequently involved location was the lower limbs;and the most frequently adopted combination of acupoints was SP6 and Zhōngjí(中极CV 3).Cluster analysis showed that the acupoints could be divided into three categories:the first group comprised SP6 alone;the second group included CV3,Guānyuán(关元CV4),Yīnlíngquán(阴陵泉SP9) and Zúsānlǐ(足三里ST36);and the third group included Pángguāngshū(膀胱俞BL28),Chéngshān(承山BL57),Tàichōng(太冲LR3),Zhìbiān(秩边 BL54),Tàixī(太溪KI6),Hégǔ(合谷 LI4),Xuèhǎi(血海SP10),Qìhǎi(气海CV6) and Shǔidào(水道ST28).Conclusion:It was found that acupuncture therapy for postoperative urinary retention after hemorrhoidectomy mainly follows the four characteristic rules:the selection of acupoints following the meridian,selection of acupoints at local points,selection of acupoints at distal points and selection of acupoints according to special symptoms.
文摘With the economic development and the popularity of application of electronic computer, electronic commerce has rapid development. More and more commerce and key business has been carried on the lnternet because Internet has the features of interaction, openness, sharing and so on. However, during the daily commerce, people worry about the security of the network system. So a new technology which can detect the unusual behavior in time has been invented in order to protect the security of network system. The system of intrusion detection needs a lot of new technology to protect the data of the network system. The application of data mining technology in the system of intrusion detection can provide a better assistant to the users to analyze the data and improve the accuracy of the checking system.
基金Scientific Research Program Funded by Shaanxi Provincial Education Department,China(No.2013JK0749)
文摘In order to accurately identify the characters associated with consumption behavior of apparel online shopping, a typical B/ C clothing enterprise in China was chosen. The target experimental database containing 2000 data records was obtained based on web service logs of sample enterprise. By means of clustering algorithm of Clementine Data Mining Software, K-means model was set up and 8 clusters of consumer were concluded. Meanwhile, the implicit information existed in consumer's characters and preferences for clothing was found. At last, 31 valuable association rules among casual wear, formal wear, and tie-in products were explored by using web analysis and Aprior algorithm. This finding will help to better understand the nature of online apparel consumption behavior and make a good progress in personalization and intelligent recommendation strategies.
文摘Distributed Data Mining is expected to discover preciously unknown, implicit and valuable information from massive data set inherently distributed over a network. In recent years several approaches to distributed data mining have been developed, but only a few of them make use of intelligent agents. This paper provides the reason for applying Multi-Agent Technology in Distributed Data Mining and presents a Distributed Data Mining System based on Multi-Agent Technology that deals with heterogeneity in such environment. Based on the advantages of both the CS model and agent-based model, the system is being able to address the specific concern of increasing scalability and enhancing performance.
文摘The publisher regrets that the article type for this publication was incorrectly labeled as a Research Article.The correct designation should be Review Article.This correction does not affect the content or conclusions of the article.The publisher apologizes for any inconvenience caused.
文摘Computer simulation for materials processing needs a huge database containing a great deal of various physical properties of materials. In order to employ the accumulated large data on materials heat treatment in the past years, it is significant to develop an intelligent database system. Based on the data mining technology for data analysis, an intelligent database web tool system of computer simulation for heat treatment process named as IndBASEweb-HT was built up. The architecture and the arithmetic of this system as well as its application were introduced.
基金supported by the Outstanding Youth Foundation of Heilongjiang Province(No.YQ2021H009).
文摘In this study,we employed a combination of genome mining and heteronuclear single quantum coherence(HSQC)-based small molecule accurate recognition technology(SMART)technology to search for fernane-type triterpenoids.Initially,potential endophytic fungi were identified through genome mining.Subsequently,fine fractions containing various fernane-type triterpenoids were selected using HSQC data collection and SMART prediction.These triterpenoids were then obtained through targeted isolation and identification.Finally,their antifungal activity was evaluated.As a result,three fernane-type triterpenoids,including two novel compounds,along with two new sesquiterpenes and four known compounds were isolated from one potential strain,Diaporthe discoidispora.Their structures were elucidated through analysis of high-resolution electrospray ionization mass spectrometry(HR-ESI-MS)and nuclear magnetic resonance(NMR)spectroscopic data.The absolute configurations were determined using single-crystal X-ray diffraction analysis and electron capture detector(ECD)analysis.Compound 3 exhibited moderate antifungal activity against Candida albicans CMCC 98001 and Aspergillus niger.
基金Henan Province Special Research Project of Tra ditional Chinese Medicine(Grant No.2022ZY1090).
文摘In the present study,data mining and network pharmacology were utilized to explore the principles and mechanisms of traditional Chinese medicine(TCM)in treating acute appendicitis.The goal was to provide a scientific basis for clinical treatment and further research on this disease.First,we searched the National Patent Database for Chinese herbal compound prescriptions used to treat acute appendicitis.We then applied frequency analysis,character and taste meridian analysis,association rule analysis,and hierarchical cluster analysis to identify the patterns of TCM treatment for acute appendicitis,selecting key combinations of Chinese medicines.Next,we screened the main active components of these key TCM based on quality markers.Using databases such as SwissTargetPrediction,SymMap,ETCM,and STRING,we analyzed the pharmacological mechanisms of these key TCM in treating acute appendicitis.Key active components and targets were further verified through molecular docking.We identified a total of 129 patents involving 316 Chinese medicines,with 24 being frequently used.The results indicated that most Chinese herbs used for acute appendicitis were heat-clearing drugs,blood-activating and stasis-removing drugs,and purging drugs.The primary active ingredients of the Rhubarb-cortex moutan-flos lonicerae combination for treating acute appendicitis included Emodin,Paeonol,Physcion,Chlorogenic acid,Chrysophanol,Rhein acid,and Aloe-emodin.These ingredients targeted key proteins such as ALB,TP53,BCL2,STAT3,IL-6,and TNF,and were involved in cellular responses to lipopolysaccharides,cell composition,and various cytokine-mediated biological processes.They also interacted with signaling pathways like AGE-RAGE,TNF,IL-17,and FoxO.Based on patent data,this study analyzed medication patterns in the treatment of acute appendicitis,discussed the possible mechanisms of key TCM combinations,and provided a scientific basis and new perspectives for the diagnosis and treatment of the disease.
文摘This article focuses on the current computer monitoring and control as the research direction,studying the application strategies of artificial intelligence and big data technology in this field.It includes an introduction to artificial intelligence and big data technology,the application strategies of artificial intelligence and big data technology in computer hardware,software,and network monitoring,as well as the application strategies of artificial intelligence and big data technology in computer process,access,and network control.This analysis aims to serve as a reference for the application of artificial intelligence and big data technology in computer monitoring and control,ultimately enhancing the security of computer systems.
文摘In the era of big data,data has gradually become an important asset of enterprises,and the application of big data technology has gradually become the key to the optimization of enterprise marketing management mode.Enterprises take the initiative to meet the development trend of the times,rely on big data technology to effectively process and analyze data,innovate decision-making methods and operation models,and achieve efficient marketing and fine management,which is an important way to improve their market competitiveness.Therefore,the author first analyzes the empowering role of big data technology on enterprise marketing management,and then discusses the difficulties faced by enterprise marketing management in the era of big data,and finally puts forward targeted improvement strategies,aiming to provide a reference for enterprises to innovate and change the marketing management mode.
基金Supported by Shanghai College Students Innovation and Entrepreneurship Training Program Project:202310268066The 16th Batch of Science And Technology Innovation Projects of Shanghai University of Traditional Chinese Medicine:SHUTCM2023010+1 种基金2024 Shanghai Oriental Talent Program Youth Project2021 High-level Local University Innovation Team Project of Shanghai University of Traditional Chinese Medicine:No.3 Shanghai Education Commission Personnel [2022]。
文摘Objective To explore the optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade using data mining.Methods Clinical studies of abdominal obesity treated with acupuncture and moxibustion,collected in the past 10 years,were searched from China Biology Medicine disc(CBMdisc),China National knowledge infrastructure(CNKI),Wanfang,China Science and Technology Journal Database(VIP),Pubmed,Embase,Google Scholar,Web of Science,(The Cumulative Index to Nursing and Allied Health Literature)CINAHL,Psyclnfo and Scopus,dated from March 1,2013 to March 31,2023.Using IBM SPSS Modeler 18.0 and other software,the frequency analysis,association-rules analysis and cluster analysis were conducted on interventions,traditional Chinese medicine(TCM)patterns,use frequency of acupoint,meridian attribution of acupoint,acupoint location,etc.Results A total of 55 articles were included,with 102 prescriptions and 71 acupoints involved.The top 3 interventions were acupoint embedding method,simple electroacupuncture and simple filiform needling.Seventeen patterns/syndromes of TCM differentiation were collected,dominated by spleen deficiency and damp blockage,spleen and kidney yang deficiency and heat accumulation in stomach and intestines.The acupoints in clinical practice were mostly at the foot-yangming stomach meridian,the conception vessel and the foot-taiyin spleen meridian,and located at the abdominal region.The top 5 acupoints of high frequency were Tianshu(ST25),Zhongwan(CV12),Daheng(SP15),Zusanli(ST36),Huaroumen(ST24)and Daimai(GB26).The specific points of the high frequency were the crossing points and front-mu points,of which,ST25 and CV12 were the most prominent.After association-rules analysis on the high-frequency acupoints,20 groups of associated acupoints were obtained,in which,the core acupoints included ST25,CV12,SP15 and ST36.Conclusion In recent 10 years,abdominal obesity is treated by the acupoints of foot-yangming stomach meridian,the conception vessel and the foot-taiyin spleen meridian.Compared with the regimen for simple obesity,the acupoints at the abdominal region are specially selected in treatment of abdominal obesity,such as ST25,CV12,SP15 and ST36.Supplementary acupoints are selected based on syndrome differentiation to simultaneously address both the disease manifestations and root causes.
基金Song Hujie’s Inheritance Studio of National Renowned Traditional Chinese Medicine Experts.
文摘Objective:To explore the core acupuncture acupoints and pattern-adapted acupoint combination rules for autism spectrum disorder(ASD)complicated with sleep disorder using clinical data mining technology.Methods:A retrospective analysis was conducted on the diagnosis and treatment data of 104 children with ASD complicated with sleep disorder admitted to Xi’an Traditional Chinese Medicine(TCM)Encephalopathy Hospital from January 2022 to December 2024.Cross-pattern main acupoints were screened via frequency statistics,chi-square test,and factor analysis;pattern-specific auxiliary acupoints were extracted by combining multiple correspondence analysis,cluster analysis,and association rule mining.Results:Ten cross-pattern main acupoints(Baihui,Sishenzhen,Language Area 1,Language Area 2,Neiguan,Shenmen,Yongquan,Xuanzhong)were identified,and acupoint combination schemes for four major TCM patterns(Hyperactivity of Liver and Heart Fire,Deficiency of Kidney Essence,Deficiency of Both Heart and Spleen,Hyperactivity of Liver with Spleen Deficiency)were established.Conclusion:Acupuncture treatment should follow the principle of“regulating spirit and calming the brain as the root,and dredging collaterals based on pattern differentiation as the branch”.The synergy between main and auxiliary acupoints can accurately regulate the disease,providing a basis for precise clinical treatment.
文摘With the rapid development of the Internet and e-commerce,e-commerce platforms have accumulated huge amounts of user behavior data.The emergence of big data technology provides a powerful means for in-depth analysis of these data and insight into user behavior patterns and preferences.This paper elaborates on the application of big data technology in the analysis of user behavior on e-commerce platforms,including the technical methods of data collection,storage,processing and analysis,as well as the specific applications in the construction of user profiles,precision marketing,personalized recommendation,user retention and churn analysis,etc.,and discusses the challenges and countermeasures faced in the application.Through the study of actual cases,it demonstrates the remarkable effectiveness of big data technology in enhancing the competitiveness of e-commerce platforms and user experience.
文摘Computer science and technology play an important role in people’s lives and work,especially in the era of big data.The application of computer science and technology is conducive to improving people’s production and living standards and provides a strong impetus for China’s social and economic development.Therefore,this paper analyzes the application of computer science and technology in the context of big data and puts forward new trends and requirements for its future development,aiming to provide some references for the computer science and technology industry.
基金2025 College Students’Innovation Training Program“Return to Poverty Monitoring and Agricultural Products Sales System”2024 College Students’Innovation Training Program“Promoting Straw Recycling to Accelerate the Sustainable Development of Agriculture”(202413207010)。
文摘With the advancement of the rural revitalization strategy,preventing poverty recurrence among previously impoverished populations has become a crucial social concern.The application of big data technology in poverty recurrence monitoring and agricultural product sales systems can effectively enhance precise identification and early warning capabilities,promoting the sustainable development of rural economies.This paper explores the application of big data technology in poverty recurrence monitoring,analyzes its innovative integration with agricultural product sales systems,and proposes an intelligent monitoring and sales platform model based on big data,aiming to provide a reference for relevant policy formulation.
文摘With the rapid development of computer network,the society has entered the information and digital era,it plays an important role in speeding up the pace of social development and providing more convenient services for people.However, the security problem of computer network is becoming more and more serious. All kinds of network viruses pose a great threat to the security of computer network.As the most advanced data processing technology currently, data mining technology can effectively resist the invasion of network virus to computer system,and plays an important role in improving the security of the computer network.This paper starts with the concept of data mining technology and the characteristics of computer network virus,and makes an in-depth analysis on the specific application of data mining technology in the computer network virus defense.
文摘This paper makes a brief description of the definition and methods of data mining.It describes the characteristics of agricultural data(value delivery,specialization,spatio-temporal bidimensionality)and the status of application of data mining technology in agriculture.