CAXASolid, a 3D CAD innovation platform with open structure, provides users with kinds of customized development strategies at different levels. The whole theoretical framework of CAXASolid is introduced. Users can cu...CAXASolid, a 3D CAD innovation platform with open structure, provides users with kinds of customized development strategies at different levels. The whole theoretical framework of CAXASolid is introduced. Users can customize their system through application integration, data integration, integration by DLL or integration by COM. Focusing on the customization techniques with COM components, the development method and process are illustrated with some case studies.展开更多
Microbial manufacturing offers an alternative approach to producing chemicals and materials in a sustainable and environmentally friendly manner.Despite its significance and widespread attention,various challenges per...Microbial manufacturing offers an alternative approach to producing chemicals and materials in a sustainable and environmentally friendly manner.Despite its significance and widespread attention,various challenges persist in its industrial application.We propose a systematic approach to microbial biotechnology-a comprehensive framework for developing customized technologies tailored to the unique characteristics of the entire process for specific products.It utilizes approaches such as simplifying the process,sequential rearrangement,and coupling steps to systematically and holistically address the bottlenecks of the entire process in microbial manufacturing,aiming to achieve optimal economic and environmental benefits.This method involves the integration of multiple disciplines,including enzymology,synthetic biology,metabolic engineering,fermentation,separation engineering,and artificial intelligence(AI)technology.Here,we present several cases involving various stages of product bioproduction,developed under the concept of systematic microbial biotechnology,to demonstrate its effectiveness and advantages.The development and application of these technological concepts hold significant potential to shape the future of a sustainable circular bioeconomy driven by microbial manufacturing.展开更多
基金Supported by National Hi-tech R&D Program of China (2002AA411010)
文摘CAXASolid, a 3D CAD innovation platform with open structure, provides users with kinds of customized development strategies at different levels. The whole theoretical framework of CAXASolid is introduced. Users can customize their system through application integration, data integration, integration by DLL or integration by COM. Focusing on the customization techniques with COM components, the development method and process are illustrated with some case studies.
基金supported by the National Natural Science Foundation of China(U2024A20478 and 32170084)the Natural Science Foundation of Shandong Province(ZR2023MC163)+1 种基金Young Taishan Scholars(TSQN201909159)Youth Innovation Promotion Association CAS(Y2021063)。
文摘Microbial manufacturing offers an alternative approach to producing chemicals and materials in a sustainable and environmentally friendly manner.Despite its significance and widespread attention,various challenges persist in its industrial application.We propose a systematic approach to microbial biotechnology-a comprehensive framework for developing customized technologies tailored to the unique characteristics of the entire process for specific products.It utilizes approaches such as simplifying the process,sequential rearrangement,and coupling steps to systematically and holistically address the bottlenecks of the entire process in microbial manufacturing,aiming to achieve optimal economic and environmental benefits.This method involves the integration of multiple disciplines,including enzymology,synthetic biology,metabolic engineering,fermentation,separation engineering,and artificial intelligence(AI)technology.Here,we present several cases involving various stages of product bioproduction,developed under the concept of systematic microbial biotechnology,to demonstrate its effectiveness and advantages.The development and application of these technological concepts hold significant potential to shape the future of a sustainable circular bioeconomy driven by microbial manufacturing.
