梳理国外知识隐藏相关文献,揭示知识隐藏的影响因素。基于Web of Science数据库,获取紧密相关的159篇文献,采用内容分析法,从能力、机会、动机、行为等4个方面归纳知识隐藏的研究内容。研究结果发现:知识隐藏行为受到能力因素、机会因...梳理国外知识隐藏相关文献,揭示知识隐藏的影响因素。基于Web of Science数据库,获取紧密相关的159篇文献,采用内容分析法,从能力、机会、动机、行为等4个方面归纳知识隐藏的研究内容。研究结果发现:知识隐藏行为受到能力因素、机会因素、动机因素等的影响,符合COM-B模型的规律;促进知识隐藏的关键环境因素主要包括环境压力、负面关系等;抑制知识隐藏的环境因素主要包括支持性环境、心理保障、积极动机等。研究结果证实COM-B模型可用于分析知识隐藏的行为轨迹,并提出实践启示及未来研究启示。展开更多
Summary: A three-dimensional (3D) graphic model of a single-chain Fv (scFv) which was derived from an anti-human placental acidic isoferritin (PAF) monoclonal antibody (MAb) was construct- ed by a homologous protein...Summary: A three-dimensional (3D) graphic model of a single-chain Fv (scFv) which was derived from an anti-human placental acidic isoferritin (PAF) monoclonal antibody (MAb) was construct- ed by a homologous protein-predicting computer algorithm on Silicon graphic computer station. The structure, surface static electricity and hydrophobicity of scFv were investigated. Computer graphic modelling indicated that all regions of scFv including the linker, variable regions of the heavy (VH) and light (VL) chains were suitable. The VH region and the VL region were involved in composing the 'hydrophobic pocket'. The linker was drifted away VH and VL regions. The complementarity determining regions (CDRs) of VH and VL regions surrounded the 'hydrophobic pocket'. This study provides a theory basis for improving antibody affinity, investigating antibody structure and analyzing the functions of VH and VL regions in antibody activity.展开更多
From the point of constructing e-commerce application system, based on the structured analysis and Object-Oriented Design method, a combined modeling method Business-Process Driven(BPD) is proposed. This method focuse...From the point of constructing e-commerce application system, based on the structured analysis and Object-Oriented Design method, a combined modeling method Business-Process Driven(BPD) is proposed. This method focuses on the business process through the development process of the system. First, the business model of the system, then commercial object model is introduced according to the business model. At last the COM-model for the system is established. The system is implemented in an iterative and incremental way. The design and analysis result of each stage is illustrated by series of views using the modeling tool UML.展开更多
1Introduction To date,in model-based gait-planning methods,the dynamics of the center of mass(COM)of bipedal robots have been analyzed by establishing their linear inverted pendulum model(LIPM)or extended forms(Owaki ...1Introduction To date,in model-based gait-planning methods,the dynamics of the center of mass(COM)of bipedal robots have been analyzed by establishing their linear inverted pendulum model(LIPM)or extended forms(Owaki et al.,2010;Englsberger et al.,2015;Xie et al.,2020).With regard to model-based gait-generation methods for uphill and downhill terrain,Kuo(2007)simulated human gait using an inverted pendulum,which provided a circular trajectory for the COM rather than a horizontal trajectory.He found that a horizontal COM trajectory consumed more muscle energy.Massah et al.(2012)utilized a 3D LIPM and the concept of zero moment point(ZMP).They developed a trajectory planner using the semi-elliptical motion equations of an NAO humanoid robot and simulated walking on various sloped terrains using the Webots platform.展开更多
文摘梳理国外知识隐藏相关文献,揭示知识隐藏的影响因素。基于Web of Science数据库,获取紧密相关的159篇文献,采用内容分析法,从能力、机会、动机、行为等4个方面归纳知识隐藏的研究内容。研究结果发现:知识隐藏行为受到能力因素、机会因素、动机因素等的影响,符合COM-B模型的规律;促进知识隐藏的关键环境因素主要包括环境压力、负面关系等;抑制知识隐藏的环境因素主要包括支持性环境、心理保障、积极动机等。研究结果证实COM-B模型可用于分析知识隐藏的行为轨迹,并提出实践启示及未来研究启示。
文摘Summary: A three-dimensional (3D) graphic model of a single-chain Fv (scFv) which was derived from an anti-human placental acidic isoferritin (PAF) monoclonal antibody (MAb) was construct- ed by a homologous protein-predicting computer algorithm on Silicon graphic computer station. The structure, surface static electricity and hydrophobicity of scFv were investigated. Computer graphic modelling indicated that all regions of scFv including the linker, variable regions of the heavy (VH) and light (VL) chains were suitable. The VH region and the VL region were involved in composing the 'hydrophobic pocket'. The linker was drifted away VH and VL regions. The complementarity determining regions (CDRs) of VH and VL regions surrounded the 'hydrophobic pocket'. This study provides a theory basis for improving antibody affinity, investigating antibody structure and analyzing the functions of VH and VL regions in antibody activity.
文摘From the point of constructing e-commerce application system, based on the structured analysis and Object-Oriented Design method, a combined modeling method Business-Process Driven(BPD) is proposed. This method focuses on the business process through the development process of the system. First, the business model of the system, then commercial object model is introduced according to the business model. At last the COM-model for the system is established. The system is implemented in an iterative and incremental way. The design and analysis result of each stage is illustrated by series of views using the modeling tool UML.
基金supported by the National Natural Science Foundation of China(No.12332023)the Zhejiang Provincial Natural Science Foundation of China(No.LY23E050010).
文摘1Introduction To date,in model-based gait-planning methods,the dynamics of the center of mass(COM)of bipedal robots have been analyzed by establishing their linear inverted pendulum model(LIPM)or extended forms(Owaki et al.,2010;Englsberger et al.,2015;Xie et al.,2020).With regard to model-based gait-generation methods for uphill and downhill terrain,Kuo(2007)simulated human gait using an inverted pendulum,which provided a circular trajectory for the COM rather than a horizontal trajectory.He found that a horizontal COM trajectory consumed more muscle energy.Massah et al.(2012)utilized a 3D LIPM and the concept of zero moment point(ZMP).They developed a trajectory planner using the semi-elliptical motion equations of an NAO humanoid robot and simulated walking on various sloped terrains using the Webots platform.
