Globally,approximately 10 million new tuberculosis(TB)cases are reported annually.Delayed diagnosis due to low detection rates is the primary cause of mortality.Although pathological examination is commonly used for d...Globally,approximately 10 million new tuberculosis(TB)cases are reported annually.Delayed diagnosis due to low detection rates is the primary cause of mortality.Although pathological examination is commonly used for diagnosing TB,5%-30%of cases remain undiagnosed,emphasizing the urgent need to establish quality control(QC)standards to reduce rates of misdiagnosis and missed diagnoses.To address this,we introduced a novel QC chip for detecting Mycobacterium tuberculosis(MTB).A quantitative pathological QC model was constructed by precisely and uniformly integrating MTB and HeLa cells into a photocurable hydrogel.This model was then sliced into uniform sections to create QC chips.It demonstrated that the QC chips exhibited no significant differences in intra-batch or inter-batch variation(coefficient of variation<5%),and remained stable at−80°C for one year.Furthermore,these chips were found to be 100%effective when tested with 240 clinical samples(200 with special staining and 40 with polymerase chain reaction).In addition to enhancing TB detection rates,this approach offers visualization,quantification,and sustainable production.Overall,this work provides a novel framework for developing QC chips for pathological testing,offering a reliable solution to enhance clinical diagnostic workflows.展开更多
Presents a one grade adaptive controller with one reference model which is built according to δ MRACS adaptive control theory and used to control an actual high order hydraulic system, and the whole hardware system u...Presents a one grade adaptive controller with one reference model which is built according to δ MRACS adaptive control theory and used to control an actual high order hydraulic system, and the whole hardware system used, which includes a AT89C51 single chip microcomputer, 74Ls373 flip latch, 6116 store, eight bit ADC0809, and so on, and the satisfactory results obtained in study on hydraulic control system.展开更多
This paper introduces a SF vector control system of a slip frequency controlled induction mo-tor with simple structure,fair performance and convenient operation.It is realized by two singlechip microprocessors and fed...This paper introduces a SF vector control system of a slip frequency controlled induction mo-tor with simple structure,fair performance and convenient operation.It is realized by two singlechip microprocessors and fed from SPWM-GTR inverter.The whole system is combined by twosubsystems,both of them are 8031 single chip microprocessors.The communication between themis coordinated by the full duplex serial port within the chip and ask-and-answer communicationmanner.The error-corrected means adopted has improved the operation reliability of the system.A series of experimental results on a 3 kW induction motor are given at the end of this paper.展开更多
A pressure force control system for hot embossing of microfluidic chips is designed with a moment motor and a ball bearing lead screw. Based on the numeric PID technique, the algorithm of pulsant integral accelerated ...A pressure force control system for hot embossing of microfluidic chips is designed with a moment motor and a ball bearing lead screw. Based on the numeric PID technique, the algorithm of pulsant integral accelerated PID control is presented and the negative effects of nonlinearity from friction, clearance and saturation are eliminated. In order to improve the quick-resixmse characteristic, independent thread technique is adopted. The method of pressure force control based on pulsant integral accelerated PID control and independent thread technique is applied with satisfactory control performance.展开更多
The paper introduces a temperature control systembased on AT89C51 single-chip-microprocessor, and discussesthe principle , hardware structure, and software design of thissystem in detail.
The high-speed computational performance is gained at the cost of huge hardware resource,which restricts the application of high-accuracy algorithms because of the limited hardware cost in practical use.To solve the p...The high-speed computational performance is gained at the cost of huge hardware resource,which restricts the application of high-accuracy algorithms because of the limited hardware cost in practical use.To solve the problem,a novel method for designing the field programmable gate array(FPGA)-based non-uniform rational B-spline(NURBS) interpolator and motion controller,which adopts the embedded multiprocessor technique,is proposed in this study.The hardware and software design for the multiprocessor,one of which is for NURBS interpolation and the other for position servo control,is presented.Performance analysis and experiments on an X-Y table are carried out,hardware cost as well as consuming time for interpolation and motion control is compared with the existing methods.The experimental and comparing results indicate that,compared with the existing methods,the proposed method can reduce the hardware cost by 97.5% using higher-accuracy interpolation algorithm within the period of 0.5 ms.A method which ensures the real-time performance and interpolation accuracy,and reduces the hardware cost significantly is proposed,and it’s practical in the use of industrial application.展开更多
基金supported by the National Natural Science Foundation of China(Nos.52325504 and 52235007)the Basic Public Welfare Research Project of Zhejiang Province(No.LGY23H160089)the Science and Technology Plan Project of Taizhou City(No.24ywa08).
文摘Globally,approximately 10 million new tuberculosis(TB)cases are reported annually.Delayed diagnosis due to low detection rates is the primary cause of mortality.Although pathological examination is commonly used for diagnosing TB,5%-30%of cases remain undiagnosed,emphasizing the urgent need to establish quality control(QC)standards to reduce rates of misdiagnosis and missed diagnoses.To address this,we introduced a novel QC chip for detecting Mycobacterium tuberculosis(MTB).A quantitative pathological QC model was constructed by precisely and uniformly integrating MTB and HeLa cells into a photocurable hydrogel.This model was then sliced into uniform sections to create QC chips.It demonstrated that the QC chips exhibited no significant differences in intra-batch or inter-batch variation(coefficient of variation<5%),and remained stable at−80°C for one year.Furthermore,these chips were found to be 100%effective when tested with 240 clinical samples(200 with special staining and 40 with polymerase chain reaction).In addition to enhancing TB detection rates,this approach offers visualization,quantification,and sustainable production.Overall,this work provides a novel framework for developing QC chips for pathological testing,offering a reliable solution to enhance clinical diagnostic workflows.
文摘Presents a one grade adaptive controller with one reference model which is built according to δ MRACS adaptive control theory and used to control an actual high order hydraulic system, and the whole hardware system used, which includes a AT89C51 single chip microcomputer, 74Ls373 flip latch, 6116 store, eight bit ADC0809, and so on, and the satisfactory results obtained in study on hydraulic control system.
文摘This paper introduces a SF vector control system of a slip frequency controlled induction mo-tor with simple structure,fair performance and convenient operation.It is realized by two singlechip microprocessors and fed from SPWM-GTR inverter.The whole system is combined by twosubsystems,both of them are 8031 single chip microprocessors.The communication between themis coordinated by the full duplex serial port within the chip and ask-and-answer communicationmanner.The error-corrected means adopted has improved the operation reliability of the system.A series of experimental results on a 3 kW induction motor are given at the end of this paper.
基金This project is supported by National Hi-tech Research and Development Program of China (863 Program, No. 2004AA404260).
文摘A pressure force control system for hot embossing of microfluidic chips is designed with a moment motor and a ball bearing lead screw. Based on the numeric PID technique, the algorithm of pulsant integral accelerated PID control is presented and the negative effects of nonlinearity from friction, clearance and saturation are eliminated. In order to improve the quick-resixmse characteristic, independent thread technique is adopted. The method of pressure force control based on pulsant integral accelerated PID control and independent thread technique is applied with satisfactory control performance.
文摘The paper introduces a temperature control systembased on AT89C51 single-chip-microprocessor, and discussesthe principle , hardware structure, and software design of thissystem in detail.
基金supported by National Key Basic Research Program of China(973 ProgramGrant No.2011CB706804)+1 种基金Shanghai Municipal Science and Technology Commission of China(Grant No.11QH1401400)Research Project of State Key Laboratory of Mechanical System & Vibration of China(Grant No.MSVMS201102)
文摘The high-speed computational performance is gained at the cost of huge hardware resource,which restricts the application of high-accuracy algorithms because of the limited hardware cost in practical use.To solve the problem,a novel method for designing the field programmable gate array(FPGA)-based non-uniform rational B-spline(NURBS) interpolator and motion controller,which adopts the embedded multiprocessor technique,is proposed in this study.The hardware and software design for the multiprocessor,one of which is for NURBS interpolation and the other for position servo control,is presented.Performance analysis and experiments on an X-Y table are carried out,hardware cost as well as consuming time for interpolation and motion control is compared with the existing methods.The experimental and comparing results indicate that,compared with the existing methods,the proposed method can reduce the hardware cost by 97.5% using higher-accuracy interpolation algorithm within the period of 0.5 ms.A method which ensures the real-time performance and interpolation accuracy,and reduces the hardware cost significantly is proposed,and it’s practical in the use of industrial application.
