Thoracic reconstructions are essential surgical techniques used to replace severely damaged tissues and restore protection to internal organs.In recent years,advancements in additive manufacturing have enabled the pro...Thoracic reconstructions are essential surgical techniques used to replace severely damaged tissues and restore protection to internal organs.In recent years,advancements in additive manufacturing have enabled the production of thoracic implants with complex geometries,offering more versatile performance.In this study,we investigated a design based on a spring-like geometry manufactured by laser powder bed fusion(LPBF),as proposed in earlier research.The biomechanical behavior of this design was analyzed using various isolated semi-ring-rib models at different levels of the rib cage.This approach enabled a comprehensive examination,leading to the proposal of several implant configurations that were incorporated into a 3D rib cage model with chest wall defects,to simulate different chest wall reconstruction scenarios.The results revealed that the implant design was too rigid for the second rib level,which therefore was excluded from the proposed implant configurations.In chest wall reconstruction simulations,the maximum stresses observed in all prostheses did not exceed 38%of the implant material's yield stress in the most unfavorable case.Additionally,all the implants showed flexibility compatible with the physiological movements of the human thorax.展开更多
The purpose of this review is to explore the intersection of computational engineering and biomedical science,highlighting the transformative potential this convergence holds for innovation in healthcare and medical r...The purpose of this review is to explore the intersection of computational engineering and biomedical science,highlighting the transformative potential this convergence holds for innovation in healthcare and medical research.The review covers key topics such as computational modelling,bioinformatics,machine learning in medical diagnostics,and the integration of wearable technology for real-time health monitoring.Major findings indicate that computational models have significantly enhanced the understanding of complex biological systems,while machine learning algorithms have improved the accuracy of disease prediction and diagnosis.The synergy between bioinformatics and computational techniques has led to breakthroughs in personalized medicine,enabling more precise treatment strategies.Additionally,the integration of wearable devices with advanced computational methods has opened new avenues for continuous health monitoring and early disease detection.The review emphasizes the need for interdisciplinary collaboration to further advance this field.Future research should focus on developing more robust and scalable computational models,enhancing data integration techniques,and addressing ethical considerations related to data privacy and security.By fostering innovation at the intersection of these disciplines,the potential to revolutionize healthcare delivery and outcomes becomes increasingly attainable.展开更多
The Literary Lab at Stanford University is one of the birthplaces of digital humanities and has maintained significant influence in this field over the years.Professor Hui Haifeng has been engaged in research on digit...The Literary Lab at Stanford University is one of the birthplaces of digital humanities and has maintained significant influence in this field over the years.Professor Hui Haifeng has been engaged in research on digital humanities and computational criticism in recent years.During his visiting scholarship at Stanford University,he participated in the activities of the Literary Lab.Taking this opportunity,he interviewed Professor Mark Algee-Hewitt,the director of the Literary Lab,discussing important topics such as the current state and reception of DH(digital humanities)in the English Department,the operations of the Literary Lab,and the landscape of computational criticism.Mark Algee-Hewitt's research focuses on the eighteenth and early nineteenth centuries in England and Germany and seeks to combine literary criticism with digital and quantitative analyses of literary texts.In particular,he is interested in the history of aesthetic theory and the development and transmission of aesthetic and philosophical concepts during the Enlightenment and Romantic periods.He is also interested in the relationship between aesthetic theory and the poetry of the long eighteenth century.Although his primary background is English literature,he also has a degree in computer science.He believes that the influence of digital humanities within the humanities disciplines is growing increasingly significant.This impact is evident in both the attraction and assistance it offers to students,as well as in the new interpretations it brings to traditional literary studies.He argues that the key to effectively integrating digital humanities into the English Department is to focus on literary research questions,exploring how digital tools can raise new questions or provide new insights into traditional research.展开更多
The Taishan Antineutrino Observatory(TAO)is a satellite experiment of the Jiangmen Underground Neutrino Observatory,located near the Taishan nuclear power plant(NPP).The TAO aims to measure the energy spectrum of reac...The Taishan Antineutrino Observatory(TAO)is a satellite experiment of the Jiangmen Underground Neutrino Observatory,located near the Taishan nuclear power plant(NPP).The TAO aims to measure the energy spectrum of reactor antineutrinos with unprecedented precision,which would benefit both reactor neutrino physics and the nuclear database.A detector geometry and event visualization system was developed for the TAO.The software was based on ROOT packages and embedded in the TAO offline software framework.This provided an intuitive tool for visualizing the detector geometry,tuning the reconstruction algorithm,understanding neutrino physics,and monitoring the operation of reactors at NPP.Further applications of the visualization system in the experimental operation of TAO and its future development are discussed.展开更多
Soft electronics,which are designed to function under mechanical deformation(such as bending,stretching,and folding),have become essential in applications like wearable electronics,artificial skin,and brain-machine in...Soft electronics,which are designed to function under mechanical deformation(such as bending,stretching,and folding),have become essential in applications like wearable electronics,artificial skin,and brain-machine interfaces.Crystalline silicon is one of the most mature and reliable materials for high-performance electronics;however,its intrinsic brittleness and rigidity pose challenges for integrating it into soft electronics.Recent research has focused on overcoming these limitations by utilizing structural design techniques to impart flexibility and stretchability to Si-based materials,such as transforming them into thin nanomembranes or nanowires.This review summarizes key strategies in geometry engineering for integrating crystalline silicon into soft electronics,from the use of hard silicon islands to creating out-of-plane foldable silicon nanofilms on flexible substrates,and ultimately to shaping silicon nanowires using vapor-liquid-solid or in-plane solid-liquid-solid techniques.We explore the latest developments in Si-based soft electronic devices,with applications in sensors,nanoprobes,robotics,and brain-machine interfaces.Finally,the paper discusses the current challenges in the field and outlines future research directions to enable the widespread adoption of silicon-based flexible electronics.展开更多
This paper delves into the visual teaching of analytic geometry facilitated by GeoGebra software.Through a meticulous analysis of the current landscape of analytic geometry instruction and the distinct advantages of G...This paper delves into the visual teaching of analytic geometry facilitated by GeoGebra software.Through a meticulous analysis of the current landscape of analytic geometry instruction and the distinct advantages of GeoGebra software,it expounds upon the imperative and feasibility of its application within the realm of analytic geometry teaching.Furthermore,it presents a detailed account of the teaching practice process grounded in this software,encompassing teaching design and the demonstration of teaching cases,and conducts an in-depth investigation and analysis of the teaching outcomes.The research findings indicate that the GeoGebra software can effectively elevate the level of visualization in analytic geometry teaching,thereby augmenting students’learning enthusiasm and comprehension capabilities.It thus offers novel perspectives and methodologies for the pedagogical reform of analytic geometry.展开更多
Fatigue failure continues to be a significant challenge in designing structural and mechanical components subjected to repeated and complex loading.While earlier studies mainly examined material properties and how str...Fatigue failure continues to be a significant challenge in designing structural and mechanical components subjected to repeated and complex loading.While earlier studies mainly examined material properties and how stress affects lifespan,this review offers the first comprehensive,multiscale comparison of strategies that optimize geometry to improve fatigue performance.This includes everything from microscopic features like the shape of graphite nodules to large-scale design elements such as fillets,notches,and overall structural layouts.We analyze and combine various methods,including topology and shape optimization,the ability of additive manufacturing to finetune internal geometries,and reliability-based design approaches.A key new contribution is our proposal of a standard way to evaluate geometry-focused fatigue design,allowing for consistent comparison and encouraging validation across different fields.Furthermore,we highlight important areas for future research,such as incorporating manufacturing flaws,using multiscale models,and integrating machine learning techniques.This work is the first to provide a broad geometric viewpoint in fatigue engineering,laying the groundwork for future design methods that are driven by data and centered on reliability.展开更多
We have developed a class of charged,anisotropic,and spherically symmetric solutions,described by the function f(R,A)=R+a A,where R represents the Ricci scalar,A is the anticurvature scalar,andαis the coupling consta...We have developed a class of charged,anisotropic,and spherically symmetric solutions,described by the function f(R,A)=R+a A,where R represents the Ricci scalar,A is the anticurvature scalar,andαis the coupling constant.The model was constructed using the Karmarkar condition to obtain the radial metric component,while the time metric component followed the approach proposed by Adler.We assumed a specific charge distribution inside the star to build the model.To ensure a smooth spacetime transition,we established boundary conditions,considering Bardeen?s solution for the exterior spacetime.Additionally,we examined various physical aspects,such as energy density,pressure components,pressure anisotropy,energy conditions,the equation of state,surface redshift,compactness factor,adiabatic index,sound speed,and the Tolman-Oppenheimer-Volkoff equilibrium condition.All these conditions were met,demonstrating that the solutions we obtained are physically viable.展开更多
In this paper,we propose a numerical calculation model of the multigroup neutron diffusion equation in 3D hexagonal geometry using the nodal Green's function method and verified it.We obtained one-dimensional tran...In this paper,we propose a numerical calculation model of the multigroup neutron diffusion equation in 3D hexagonal geometry using the nodal Green's function method and verified it.We obtained one-dimensional transverse integrated equations using the transverse integration procedure over 3D hexagonal geometry and denoted the solutions as a nodal Green's functions under the Neumann boundary condition.By applying a quadratic polynomial expansion of the transverse-averaged quantities,we derived the net neutron current coupling equation,equation for the expansion coefficients of the transverse-averaged neutron flux,and formulas for the coefficient matrix of these equations.We formulated the closed system of equations in correspondence with the boundary conditions.The proposed model was tested by comparing it with the benchmark for the VVER-440 reactor,and the numerical results were in good agreement with the reference solutions.展开更多
As an essential element of intelligent trans-port systems,Internet of vehicles(IoV)has brought an immersive user experience recently.Meanwhile,the emergence of mobile edge computing(MEC)has enhanced the computational ...As an essential element of intelligent trans-port systems,Internet of vehicles(IoV)has brought an immersive user experience recently.Meanwhile,the emergence of mobile edge computing(MEC)has enhanced the computational capability of the vehicle which reduces task processing latency and power con-sumption effectively and meets the quality of service requirements of vehicle users.However,there are still some problems in the MEC-assisted IoV system such as poor connectivity and high cost.Unmanned aerial vehicles(UAVs)equipped with MEC servers have become a promising approach for providing com-munication and computing services to mobile vehi-cles.Hence,in this article,an optimal framework for the UAV-assisted MEC system for IoV to minimize the average system cost is presented.Through joint consideration of computational offloading decisions and computational resource allocation,the optimiza-tion problem of our proposed architecture is presented to reduce system energy consumption and delay.For purpose of tackling this issue,the original non-convex issue is converted into a convex issue and the alternat-ing direction method of multipliers-based distributed optimal scheme is developed.The simulation results illustrate that the presented scheme can enhance the system performance dramatically with regard to other schemes,and the convergence of the proposed scheme is also significant.展开更多
Reasonable field acquisition geometry can not only guide seismic exploration to obtain sufficient geological information of target body,but also reduce acquisition cost to the maximum.In this study,building on convent...Reasonable field acquisition geometry can not only guide seismic exploration to obtain sufficient geological information of target body,but also reduce acquisition cost to the maximum.In this study,building on conventional ray-based geometry design methods,we incorporate imaging results as a constraint to optimize the geometry design and evaluate its effectiveness.Firstly,the geological model of the target layer is established based on the geological data of the study area and surface seismic data combined with exploration tasks.Then,the ray-tracing method is employed to simulate and assess the proposed geometry design,verifying whether its parameters meet the exploration requirements.Finally,the imaging effect of the designed geometry on the target layer is tested by the cross-well seismic reverse time migration method.This methodology was applied to design the cross-well seismic acquisition geometry for offshore deviated wells in the X Oilfield.The simulation results demonstrate that the imaging-driven geometry design approach effectively guides field operations,enhances the imaging quality of the target layer,and reduces acquisition costs.展开更多
This study first demonstrates the potential of organic photoabsorbing blends in overcoming a critical limitation of metal oxide photoanodes in tandem modules:insufficient photogenerated current.Various organic blends,...This study first demonstrates the potential of organic photoabsorbing blends in overcoming a critical limitation of metal oxide photoanodes in tandem modules:insufficient photogenerated current.Various organic blends,including PTB7-Th:FOIC,PTB7-Th:O6T-4F,PM6:Y6,and PM6:FM,were systematically tested.When coupled with electron transport layer(ETL)contacts,these blends exhibit exceptional charge separation and extraction,with PM6:Y6 achieving saturation photocurrents up to 16.8 mA cm^(-2) at 1.23 VRHE(oxygen evolution thermodynamic potential).For the first time,a tandem structure utilizing organic photoanodes has been computationally designed and fabricated and the implementation of a double PM6:Y6 photoanode/photovoltaic structure resulted in photogenerated currents exceeding 7mA cm^(-2) at 0 VRHE(hydrogen evolution thermodynamic potential)and anodic current onset potentials as low as-0.5 VRHE.The herein-presented organic-based approach paves the way for further exploration of different blend combinations to target specific oxidative reactions by selecting precise donor/acceptor candidates among the multiple existing ones.展开更多
The Main Himalayan Thrust(MHT),where the 2015 MW7.8 Gorkha earthquake occurred,features the most seismicity of any structure in Nepal.The structural complexity of the MHT makes it difficult to obtain a definitive inte...The Main Himalayan Thrust(MHT),where the 2015 MW7.8 Gorkha earthquake occurred,features the most seismicity of any structure in Nepal.The structural complexity of the MHT makes it difficult to obtain a definitive interpretation of deep seismogenic structures.The application of new methods and data in this region is necessary to enhance local seismic hazard analyses.In this study,we used a well-designed machine learning-based earthquake location workflow(LOC-FLOW),which incorporates machine learning phase picking,phase association,absolute location,and double-difference relative location,to process seismic data collected by the Hi-CLIMB and NAMASTE seismic networks.We built a high-precision earthquake catalog of both the quiet-period and aftershock seismicity in this region.The seismicity distribution suggests that the quietperiod seismicity(388 events)was controlled by a mid-crustal ramp and the aftershock seismicity(12,669 events)was controlled by several geological structures of the MHT.The higher-level detail of the catalogs derived from this machine learning method reveal clearer structural characteristics,showing how the flat-ramp geometry and a possible duplex structure affect the depth distribution of the seismic events,and how a tear fault changes this distribution along strike.展开更多
The accuracy of numerical computation heavily relies on appropriate meshing,whichserves as the foundation for numerical computation.Although adaptive refinement methods areavailable,an adaptive numerical solution is l...The accuracy of numerical computation heavily relies on appropriate meshing,whichserves as the foundation for numerical computation.Although adaptive refinement methods areavailable,an adaptive numerical solution is likely to be ineffective if it originates from a poorly ini-tial mesh.Therefore,it is crucial to generate meshes that accurately capture the geometric features.As an indispensable input in meshing methods,the Mesh Size Function(MSF)determines the qual-ity of the generated mesh.However,the current generation of MSF involves human participation tospecify numerous parameters,leading to difficulties in practical usage.Considering the capacity ofmachine learning to reveal the latent relationships within data,this paper proposes a novel machinelearning method,Implicit Geometry Neural Network(IGNN),for automatic prediction of appro-priate MSFs based on the existing mesh data,enabling the generation of unstructured meshes thatalign precisely with geometric features.IGNN employs the generative adversarial theory to learnthe mapping between the implicit representation of the geometry(Signed Distance Function,SDF)and the corresponding MSF.Experimental results show that the proposed method is capableof automatically generating appropriate meshes and achieving comparable meshing results com-pared to traditional methods.This paper demonstrates the possibility of significantly decreasingthe workload of mesh generation using machine learning techniques,and it is expected to increasethe automation level of mesh generation.展开更多
1 Summary Mathematical modeling has become a cornerstone in understanding the complex dynamics of infectious diseases and chronic health conditions.With the advent of more refined computational techniques,researchers ...1 Summary Mathematical modeling has become a cornerstone in understanding the complex dynamics of infectious diseases and chronic health conditions.With the advent of more refined computational techniques,researchers are now able to incorporate intricate features such as delays,stochastic effects,fractional dynamics,variable-order systems,and uncertainty into epidemic models.These advancements not only improve predictive accuracy but also enable deeper insights into disease transmission,control,and policy-making.Tashfeen et al.展开更多
Meshing temperature analyses of polymer gears reported in the literature mainly concern the effects of various material combinations and loading conditions,as their impacts could be seen in the first few meshing cycle...Meshing temperature analyses of polymer gears reported in the literature mainly concern the effects of various material combinations and loading conditions,as their impacts could be seen in the first few meshing cycles.However,the effects of tooth geometry parameters could manifest as the meshing cycles increase.This study investigated the effects of tooth geometry parameters on the multi-cycle meshing temperature of polyoxymethylene(POM)worm gears,aiming to control the meshing temperature elevation by tuning the tooth geometry.Firstly,a finite element(FE)model capable of separately calculating the heat generation and simulating the heat propagation was established.Moreover,an adaptive iteration algorithm was proposed within the FE framework to capture the influence of the heat generation variation from cycle to cycle.This algorithm proved to be feasible and highly efficient compared with experimental results from the literature and simulated results via the full-iteration algorithm.Multi-cycle meshing temperature analyses were conducted on a series of POM worm gears with different tooth geometry parameters.The results reveal that,within the range of 14.5°to 25°,a pressure angle of 25°is favorable for reducing the peak surface temperature and overall body temperature of POM worm gears,which influence flank wear and load-carrying capability,respectively.However,addendum modification should be weighed because it helps with load bearing but increases the risk of severe flank wear.This paper proposes an efficient iteration algorithm for multi-cycle meshing temperature analysis of polymer gears and proves the feasibility of controlling the meshing temperature elevation during multiple cycles by tuning tooth geometry.展开更多
Adolescent idiopathic scoliosis(AIS)is a dynamic progression during growth,which requires long-term collaborations and efforts from clinicians,patients and their families.It would be beneficial to have a precise inter...Adolescent idiopathic scoliosis(AIS)is a dynamic progression during growth,which requires long-term collaborations and efforts from clinicians,patients and their families.It would be beneficial to have a precise intervention based on cross-scale understandings of the etiology,real-time sensing and actuating to enable early detection,screening and personalized treatment.We argue that merging computational intelligence and wearable technologies can bridge the gap between the current trajectory of the techniques applied to AIS and this vision.Wearable technologies such as inertial measurement units(IMUs)and surface electromyography(sEMG)have shown great potential in monitoring spinal curvature and muscle activity in real-time.For instance,IMUs can track the kinematics of the spine during daily activities,while sEMG can detect asymmetric muscle activation patterns that may contribute to scoliosis progression.Computational intelligence,particularly deep learning algorithms,can process these multi-modal data streams to identify early signs of scoliosis and adapt treatment strategies dynamically.By using their combination,we can find potential solutions for a better understanding of the disease,a more effective and intelligent way for treatment and rehabilitation.展开更多
A DFN-DEC(discrete fracture network-distinct element code)method based on the MATLAB platform is developed to generate heterogeneous DFN.Subsequently,the effects of the spatial variability(the meanμand the standard d...A DFN-DEC(discrete fracture network-distinct element code)method based on the MATLAB platform is developed to generate heterogeneous DFN.Subsequently,the effects of the spatial variability(the meanμand the standard deviationσ)of the geometric properties(i.e.,the fracture dip D,the trace length T and the spacing S)of both the gently-dipping(denoted with 1)and the steeply-dipping(denoted with 2)fractures on the stability of granite slope are investigated.Results indicate that the proposed DFN-DEC method is robust,generating fracture networks that resemble reality.In addition,the spatial variability of fracture geometry,influencing the structure of granite slope,plays a significant role in slope stability.The mean stability of the slope decreases with the increase ofμ_(D_(1))(the mean of gently-dipping fracture dip),σ_(D_(2))(the mean of steeply-dipping fracture dip),μ_(T_(1))(the mean of gently-dipping fracture trace length),μ_(T_(2))(the mean of steeply-dipping fracture trace length),σ_(T_(1))(the standard deviation of gently-dipping fracture trace length),σ_(T_(2))(the standard deviation of steeply-dipping fracture trace length),and the decrease ofσ_(D_(1))(the standard deviation of gently-dipping fracture dip),μ_(D_(2))(the standard deviation of steeply-dipping fracture dip),μ_(S_(1))(the mean of gently-dipping fracture spacing)andμ_(S_(2))(the mean of steeply-dipping fracture spacing).Among them,μ_(T_(1)),μ_(D_(1))andμ_(S_(1))have the major impact.When the fracture spacing is large,the variability in the fracture geometry becomes less relevant to slope stability.When within some ranges of the fracture spacing,the spatial varying of dips can increase the slope stability by forming an interlaced structure.The results also show that the effects of the variability of trace length on slope stability depend on the variability of dip.These findings highlight the importance of spatial variability in the geometry of fractures to rock slope stability analysis.展开更多
Biotechnological strategies for plastic depolymerization and recycling have emerged as transformative approaches to combat the global plastic pollution crisis,aligning with the principles of a sustainable and circular...Biotechnological strategies for plastic depolymerization and recycling have emerged as transformative approaches to combat the global plastic pollution crisis,aligning with the principles of a sustainable and circular economy.Despite advances in engineering PET hydrolases,the degradation process is frequently compromised by product inhibition and the heterogeneity of final products,thereby obstructing subsequent PET recondensation and impeding the synthesis of high-value derivatives.In this work,we utilized previously devised computational strategies to redesign a thermostable DuraMHETase,achieving an apparent melting temperature of 72℃ in complex with MHET and a 6-fold higher in total turnover number(TTN)toward MHET than the wild-type enzyme at 60℃.The fused enzyme system composed of DuraMHETase and TurboPETase demonstrated higher efficiency than other PET hydrolases and the separated dual enzyme systems.Furthermore,we identified both exo-and endo-PETase activities in DuraMHETase,whereas the endo-activity was previously unobserved at ambient temperatures.These results expand the functional scope of MHETase beyond mere intermediate hydrolysis,and may provide guidance for the development of more synergistic approaches to plastic biodepolymerization and recycling.展开更多
文摘Thoracic reconstructions are essential surgical techniques used to replace severely damaged tissues and restore protection to internal organs.In recent years,advancements in additive manufacturing have enabled the production of thoracic implants with complex geometries,offering more versatile performance.In this study,we investigated a design based on a spring-like geometry manufactured by laser powder bed fusion(LPBF),as proposed in earlier research.The biomechanical behavior of this design was analyzed using various isolated semi-ring-rib models at different levels of the rib cage.This approach enabled a comprehensive examination,leading to the proposal of several implant configurations that were incorporated into a 3D rib cage model with chest wall defects,to simulate different chest wall reconstruction scenarios.The results revealed that the implant design was too rigid for the second rib level,which therefore was excluded from the proposed implant configurations.In chest wall reconstruction simulations,the maximum stresses observed in all prostheses did not exceed 38%of the implant material's yield stress in the most unfavorable case.Additionally,all the implants showed flexibility compatible with the physiological movements of the human thorax.
文摘The purpose of this review is to explore the intersection of computational engineering and biomedical science,highlighting the transformative potential this convergence holds for innovation in healthcare and medical research.The review covers key topics such as computational modelling,bioinformatics,machine learning in medical diagnostics,and the integration of wearable technology for real-time health monitoring.Major findings indicate that computational models have significantly enhanced the understanding of complex biological systems,while machine learning algorithms have improved the accuracy of disease prediction and diagnosis.The synergy between bioinformatics and computational techniques has led to breakthroughs in personalized medicine,enabling more precise treatment strategies.Additionally,the integration of wearable devices with advanced computational methods has opened new avenues for continuous health monitoring and early disease detection.The review emphasizes the need for interdisciplinary collaboration to further advance this field.Future research should focus on developing more robust and scalable computational models,enhancing data integration techniques,and addressing ethical considerations related to data privacy and security.By fostering innovation at the intersection of these disciplines,the potential to revolutionize healthcare delivery and outcomes becomes increasingly attainable.
文摘The Literary Lab at Stanford University is one of the birthplaces of digital humanities and has maintained significant influence in this field over the years.Professor Hui Haifeng has been engaged in research on digital humanities and computational criticism in recent years.During his visiting scholarship at Stanford University,he participated in the activities of the Literary Lab.Taking this opportunity,he interviewed Professor Mark Algee-Hewitt,the director of the Literary Lab,discussing important topics such as the current state and reception of DH(digital humanities)in the English Department,the operations of the Literary Lab,and the landscape of computational criticism.Mark Algee-Hewitt's research focuses on the eighteenth and early nineteenth centuries in England and Germany and seeks to combine literary criticism with digital and quantitative analyses of literary texts.In particular,he is interested in the history of aesthetic theory and the development and transmission of aesthetic and philosophical concepts during the Enlightenment and Romantic periods.He is also interested in the relationship between aesthetic theory and the poetry of the long eighteenth century.Although his primary background is English literature,he also has a degree in computer science.He believes that the influence of digital humanities within the humanities disciplines is growing increasingly significant.This impact is evident in both the attraction and assistance it offers to students,as well as in the new interpretations it brings to traditional literary studies.He argues that the key to effectively integrating digital humanities into the English Department is to focus on literary research questions,exploring how digital tools can raise new questions or provide new insights into traditional research.
基金supported by the National Natural Science Foundation of China(Nos.12175321,11975021,and 11675275)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA10010900)。
文摘The Taishan Antineutrino Observatory(TAO)is a satellite experiment of the Jiangmen Underground Neutrino Observatory,located near the Taishan nuclear power plant(NPP).The TAO aims to measure the energy spectrum of reactor antineutrinos with unprecedented precision,which would benefit both reactor neutrino physics and the nuclear database.A detector geometry and event visualization system was developed for the TAO.The software was based on ROOT packages and embedded in the TAO offline software framework.This provided an intuitive tool for visualizing the detector geometry,tuning the reconstruction algorithm,understanding neutrino physics,and monitoring the operation of reactors at NPP.Further applications of the visualization system in the experimental operation of TAO and its future development are discussed.
基金the National Natural Science Foundation of China under granted No.62104100National Key Research Program of China under No.92164201+1 种基金National Natural Science Foundation of China for Distinguished Young Scholars under No.62325403National Natural Science Foundation of China under No.61934004.
文摘Soft electronics,which are designed to function under mechanical deformation(such as bending,stretching,and folding),have become essential in applications like wearable electronics,artificial skin,and brain-machine interfaces.Crystalline silicon is one of the most mature and reliable materials for high-performance electronics;however,its intrinsic brittleness and rigidity pose challenges for integrating it into soft electronics.Recent research has focused on overcoming these limitations by utilizing structural design techniques to impart flexibility and stretchability to Si-based materials,such as transforming them into thin nanomembranes or nanowires.This review summarizes key strategies in geometry engineering for integrating crystalline silicon into soft electronics,from the use of hard silicon islands to creating out-of-plane foldable silicon nanofilms on flexible substrates,and ultimately to shaping silicon nanowires using vapor-liquid-solid or in-plane solid-liquid-solid techniques.We explore the latest developments in Si-based soft electronic devices,with applications in sensors,nanoprobes,robotics,and brain-machine interfaces.Finally,the paper discusses the current challenges in the field and outlines future research directions to enable the widespread adoption of silicon-based flexible electronics.
基金The 2024 Undergraduate Education Teaching Research and Reform Project of Colleges and Universities in the Autonomous Region“Construction of School-based Digital Resources for Ideological and Political Education in the Course of Analytic Geometry”(XJGXJGPTB-2024104)。
文摘This paper delves into the visual teaching of analytic geometry facilitated by GeoGebra software.Through a meticulous analysis of the current landscape of analytic geometry instruction and the distinct advantages of GeoGebra software,it expounds upon the imperative and feasibility of its application within the realm of analytic geometry teaching.Furthermore,it presents a detailed account of the teaching practice process grounded in this software,encompassing teaching design and the demonstration of teaching cases,and conducts an in-depth investigation and analysis of the teaching outcomes.The research findings indicate that the GeoGebra software can effectively elevate the level of visualization in analytic geometry teaching,thereby augmenting students’learning enthusiasm and comprehension capabilities.It thus offers novel perspectives and methodologies for the pedagogical reform of analytic geometry.
文摘Fatigue failure continues to be a significant challenge in designing structural and mechanical components subjected to repeated and complex loading.While earlier studies mainly examined material properties and how stress affects lifespan,this review offers the first comprehensive,multiscale comparison of strategies that optimize geometry to improve fatigue performance.This includes everything from microscopic features like the shape of graphite nodules to large-scale design elements such as fillets,notches,and overall structural layouts.We analyze and combine various methods,including topology and shape optimization,the ability of additive manufacturing to finetune internal geometries,and reliability-based design approaches.A key new contribution is our proposal of a standard way to evaluate geometry-focused fatigue design,allowing for consistent comparison and encouraging validation across different fields.Furthermore,we highlight important areas for future research,such as incorporating manufacturing flaws,using multiscale models,and integrating machine learning techniques.This work is the first to provide a broad geometric viewpoint in fatigue engineering,laying the groundwork for future design methods that are driven by data and centered on reliability.
基金Deanship of Research and Graduate Studies at King Khalid University for funding this work through Large Research Project under Grant No.RGP2/30/45。
文摘We have developed a class of charged,anisotropic,and spherically symmetric solutions,described by the function f(R,A)=R+a A,where R represents the Ricci scalar,A is the anticurvature scalar,andαis the coupling constant.The model was constructed using the Karmarkar condition to obtain the radial metric component,while the time metric component followed the approach proposed by Adler.We assumed a specific charge distribution inside the star to build the model.To ensure a smooth spacetime transition,we established boundary conditions,considering Bardeen?s solution for the exterior spacetime.Additionally,we examined various physical aspects,such as energy density,pressure components,pressure anisotropy,energy conditions,the equation of state,surface redshift,compactness factor,adiabatic index,sound speed,and the Tolman-Oppenheimer-Volkoff equilibrium condition.All these conditions were met,demonstrating that the solutions we obtained are physically viable.
文摘In this paper,we propose a numerical calculation model of the multigroup neutron diffusion equation in 3D hexagonal geometry using the nodal Green's function method and verified it.We obtained one-dimensional transverse integrated equations using the transverse integration procedure over 3D hexagonal geometry and denoted the solutions as a nodal Green's functions under the Neumann boundary condition.By applying a quadratic polynomial expansion of the transverse-averaged quantities,we derived the net neutron current coupling equation,equation for the expansion coefficients of the transverse-averaged neutron flux,and formulas for the coefficient matrix of these equations.We formulated the closed system of equations in correspondence with the boundary conditions.The proposed model was tested by comparing it with the benchmark for the VVER-440 reactor,and the numerical results were in good agreement with the reference solutions.
基金in part by the National Natural Science Foundation of China(NSFC)under Grant 62371012in part by the Beijing Natural Science Foundation under Grant 4252001.
文摘As an essential element of intelligent trans-port systems,Internet of vehicles(IoV)has brought an immersive user experience recently.Meanwhile,the emergence of mobile edge computing(MEC)has enhanced the computational capability of the vehicle which reduces task processing latency and power con-sumption effectively and meets the quality of service requirements of vehicle users.However,there are still some problems in the MEC-assisted IoV system such as poor connectivity and high cost.Unmanned aerial vehicles(UAVs)equipped with MEC servers have become a promising approach for providing com-munication and computing services to mobile vehi-cles.Hence,in this article,an optimal framework for the UAV-assisted MEC system for IoV to minimize the average system cost is presented.Through joint consideration of computational offloading decisions and computational resource allocation,the optimiza-tion problem of our proposed architecture is presented to reduce system energy consumption and delay.For purpose of tackling this issue,the original non-convex issue is converted into a convex issue and the alternat-ing direction method of multipliers-based distributed optimal scheme is developed.The simulation results illustrate that the presented scheme can enhance the system performance dramatically with regard to other schemes,and the convergence of the proposed scheme is also significant.
基金funded by the Young Scientists Fund of the National Natural Science Foundation of China(42304135)the scientific research project of Gansu Coal Geology Bureau(2023-07).
文摘Reasonable field acquisition geometry can not only guide seismic exploration to obtain sufficient geological information of target body,but also reduce acquisition cost to the maximum.In this study,building on conventional ray-based geometry design methods,we incorporate imaging results as a constraint to optimize the geometry design and evaluate its effectiveness.Firstly,the geological model of the target layer is established based on the geological data of the study area and surface seismic data combined with exploration tasks.Then,the ray-tracing method is employed to simulate and assess the proposed geometry design,verifying whether its parameters meet the exploration requirements.Finally,the imaging effect of the designed geometry on the target layer is tested by the cross-well seismic reverse time migration method.This methodology was applied to design the cross-well seismic acquisition geometry for offshore deviated wells in the X Oilfield.The simulation results demonstrate that the imaging-driven geometry design approach effectively guides field operations,enhances the imaging quality of the target layer,and reduces acquisition costs.
基金partly funded by a BIST Ignite Programme grant from the Barcelona Institute of Science and Technology(Code:MOLOPEC)financial support from LICROX and SOREC2 EUFunded projects(Codes:951843 and 101084326)+7 种基金the BIST Program,and Severo Ochoa Programpartially funded by CEX2019-000910-S(MCIN/AEI/10.13039/501100011033 and PID2020-112650RBI00),Fundació Cellex,Fundació Mir-PuigGeneralitat de Catalunya through CERCAfunding from the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101081441financial support by the Agencia Estatal de Investigación(grant PRE2018-084881)the financial support by from the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101081441support from the MCIN/AEI JdC-F Fellowship(FJC2020-043223-I)the Severo Ochoa Excellence Postdoctoral Fellowship(CEX2019-000910-S).
文摘This study first demonstrates the potential of organic photoabsorbing blends in overcoming a critical limitation of metal oxide photoanodes in tandem modules:insufficient photogenerated current.Various organic blends,including PTB7-Th:FOIC,PTB7-Th:O6T-4F,PM6:Y6,and PM6:FM,were systematically tested.When coupled with electron transport layer(ETL)contacts,these blends exhibit exceptional charge separation and extraction,with PM6:Y6 achieving saturation photocurrents up to 16.8 mA cm^(-2) at 1.23 VRHE(oxygen evolution thermodynamic potential).For the first time,a tandem structure utilizing organic photoanodes has been computationally designed and fabricated and the implementation of a double PM6:Y6 photoanode/photovoltaic structure resulted in photogenerated currents exceeding 7mA cm^(-2) at 0 VRHE(hydrogen evolution thermodynamic potential)and anodic current onset potentials as low as-0.5 VRHE.The herein-presented organic-based approach paves the way for further exploration of different blend combinations to target specific oxidative reactions by selecting precise donor/acceptor candidates among the multiple existing ones.
基金funded by the National Key R&D Program of China(2022YFF0800601)National Natural Science Foundation of China(42174069,U1939204).
文摘The Main Himalayan Thrust(MHT),where the 2015 MW7.8 Gorkha earthquake occurred,features the most seismicity of any structure in Nepal.The structural complexity of the MHT makes it difficult to obtain a definitive interpretation of deep seismogenic structures.The application of new methods and data in this region is necessary to enhance local seismic hazard analyses.In this study,we used a well-designed machine learning-based earthquake location workflow(LOC-FLOW),which incorporates machine learning phase picking,phase association,absolute location,and double-difference relative location,to process seismic data collected by the Hi-CLIMB and NAMASTE seismic networks.We built a high-precision earthquake catalog of both the quiet-period and aftershock seismicity in this region.The seismicity distribution suggests that the quietperiod seismicity(388 events)was controlled by a mid-crustal ramp and the aftershock seismicity(12,669 events)was controlled by several geological structures of the MHT.The higher-level detail of the catalogs derived from this machine learning method reveal clearer structural characteristics,showing how the flat-ramp geometry and a possible duplex structure affect the depth distribution of the seismic events,and how a tear fault changes this distribution along strike.
基金co-supported by the Aeronautical Science Foundation of China(Nos.2018ZA52002 and 2019ZA052011)。
文摘The accuracy of numerical computation heavily relies on appropriate meshing,whichserves as the foundation for numerical computation.Although adaptive refinement methods areavailable,an adaptive numerical solution is likely to be ineffective if it originates from a poorly ini-tial mesh.Therefore,it is crucial to generate meshes that accurately capture the geometric features.As an indispensable input in meshing methods,the Mesh Size Function(MSF)determines the qual-ity of the generated mesh.However,the current generation of MSF involves human participation tospecify numerous parameters,leading to difficulties in practical usage.Considering the capacity ofmachine learning to reveal the latent relationships within data,this paper proposes a novel machinelearning method,Implicit Geometry Neural Network(IGNN),for automatic prediction of appro-priate MSFs based on the existing mesh data,enabling the generation of unstructured meshes thatalign precisely with geometric features.IGNN employs the generative adversarial theory to learnthe mapping between the implicit representation of the geometry(Signed Distance Function,SDF)and the corresponding MSF.Experimental results show that the proposed method is capableof automatically generating appropriate meshes and achieving comparable meshing results com-pared to traditional methods.This paper demonstrates the possibility of significantly decreasingthe workload of mesh generation using machine learning techniques,and it is expected to increasethe automation level of mesh generation.
文摘1 Summary Mathematical modeling has become a cornerstone in understanding the complex dynamics of infectious diseases and chronic health conditions.With the advent of more refined computational techniques,researchers are now able to incorporate intricate features such as delays,stochastic effects,fractional dynamics,variable-order systems,and uncertainty into epidemic models.These advancements not only improve predictive accuracy but also enable deeper insights into disease transmission,control,and policy-making.Tashfeen et al.
基金Supported by National Key R&D Program of China(Grant No.2019YFE0121300)。
文摘Meshing temperature analyses of polymer gears reported in the literature mainly concern the effects of various material combinations and loading conditions,as their impacts could be seen in the first few meshing cycles.However,the effects of tooth geometry parameters could manifest as the meshing cycles increase.This study investigated the effects of tooth geometry parameters on the multi-cycle meshing temperature of polyoxymethylene(POM)worm gears,aiming to control the meshing temperature elevation by tuning the tooth geometry.Firstly,a finite element(FE)model capable of separately calculating the heat generation and simulating the heat propagation was established.Moreover,an adaptive iteration algorithm was proposed within the FE framework to capture the influence of the heat generation variation from cycle to cycle.This algorithm proved to be feasible and highly efficient compared with experimental results from the literature and simulated results via the full-iteration algorithm.Multi-cycle meshing temperature analyses were conducted on a series of POM worm gears with different tooth geometry parameters.The results reveal that,within the range of 14.5°to 25°,a pressure angle of 25°is favorable for reducing the peak surface temperature and overall body temperature of POM worm gears,which influence flank wear and load-carrying capability,respectively.However,addendum modification should be weighed because it helps with load bearing but increases the risk of severe flank wear.This paper proposes an efficient iteration algorithm for multi-cycle meshing temperature analysis of polymer gears and proves the feasibility of controlling the meshing temperature elevation during multiple cycles by tuning tooth geometry.
基金by National Natural Science Foundation of China(No.62306083)the Postdoctoral Science Foundation of Heilongjiang Province of China(LBH-Z22175)the Ministry of Industry and Information Technology。
文摘Adolescent idiopathic scoliosis(AIS)is a dynamic progression during growth,which requires long-term collaborations and efforts from clinicians,patients and their families.It would be beneficial to have a precise intervention based on cross-scale understandings of the etiology,real-time sensing and actuating to enable early detection,screening and personalized treatment.We argue that merging computational intelligence and wearable technologies can bridge the gap between the current trajectory of the techniques applied to AIS and this vision.Wearable technologies such as inertial measurement units(IMUs)and surface electromyography(sEMG)have shown great potential in monitoring spinal curvature and muscle activity in real-time.For instance,IMUs can track the kinematics of the spine during daily activities,while sEMG can detect asymmetric muscle activation patterns that may contribute to scoliosis progression.Computational intelligence,particularly deep learning algorithms,can process these multi-modal data streams to identify early signs of scoliosis and adapt treatment strategies dynamically.By using their combination,we can find potential solutions for a better understanding of the disease,a more effective and intelligent way for treatment and rehabilitation.
基金supported by the National Natural Science Foundation of China(Nos.41807264,41972289)the Engineering Research Center of Rock-Soil Drilling&Excavation and Protection,Ministry of Education(No.202102)+3 种基金the Key Laboratory of Geological Hazards on Three Gorges Reservoir Area(China Three Gorges University),Ministry of Education(No.2020KDZ01)the Fundamental Research Funds for the Central Universities,China University of Geosciences(Wuhan)(Nos.CUG170686,CUGQY1932)the China Scholarship Council(No.201406410032)the Science and Technology Research Project of Education Department of Hubei Province(Nos.B2019452,B2024509)。
文摘A DFN-DEC(discrete fracture network-distinct element code)method based on the MATLAB platform is developed to generate heterogeneous DFN.Subsequently,the effects of the spatial variability(the meanμand the standard deviationσ)of the geometric properties(i.e.,the fracture dip D,the trace length T and the spacing S)of both the gently-dipping(denoted with 1)and the steeply-dipping(denoted with 2)fractures on the stability of granite slope are investigated.Results indicate that the proposed DFN-DEC method is robust,generating fracture networks that resemble reality.In addition,the spatial variability of fracture geometry,influencing the structure of granite slope,plays a significant role in slope stability.The mean stability of the slope decreases with the increase ofμ_(D_(1))(the mean of gently-dipping fracture dip),σ_(D_(2))(the mean of steeply-dipping fracture dip),μ_(T_(1))(the mean of gently-dipping fracture trace length),μ_(T_(2))(the mean of steeply-dipping fracture trace length),σ_(T_(1))(the standard deviation of gently-dipping fracture trace length),σ_(T_(2))(the standard deviation of steeply-dipping fracture trace length),and the decrease ofσ_(D_(1))(the standard deviation of gently-dipping fracture dip),μ_(D_(2))(the standard deviation of steeply-dipping fracture dip),μ_(S_(1))(the mean of gently-dipping fracture spacing)andμ_(S_(2))(the mean of steeply-dipping fracture spacing).Among them,μ_(T_(1)),μ_(D_(1))andμ_(S_(1))have the major impact.When the fracture spacing is large,the variability in the fracture geometry becomes less relevant to slope stability.When within some ranges of the fracture spacing,the spatial varying of dips can increase the slope stability by forming an interlaced structure.The results also show that the effects of the variability of trace length on slope stability depend on the variability of dip.These findings highlight the importance of spatial variability in the geometry of fractures to rock slope stability analysis.
文摘Biotechnological strategies for plastic depolymerization and recycling have emerged as transformative approaches to combat the global plastic pollution crisis,aligning with the principles of a sustainable and circular economy.Despite advances in engineering PET hydrolases,the degradation process is frequently compromised by product inhibition and the heterogeneity of final products,thereby obstructing subsequent PET recondensation and impeding the synthesis of high-value derivatives.In this work,we utilized previously devised computational strategies to redesign a thermostable DuraMHETase,achieving an apparent melting temperature of 72℃ in complex with MHET and a 6-fold higher in total turnover number(TTN)toward MHET than the wild-type enzyme at 60℃.The fused enzyme system composed of DuraMHETase and TurboPETase demonstrated higher efficiency than other PET hydrolases and the separated dual enzyme systems.Furthermore,we identified both exo-and endo-PETase activities in DuraMHETase,whereas the endo-activity was previously unobserved at ambient temperatures.These results expand the functional scope of MHETase beyond mere intermediate hydrolysis,and may provide guidance for the development of more synergistic approaches to plastic biodepolymerization and recycling.
