I. THE COMPLEXITY OFBIOLOGICAL RESPONSESFor an organism, to be living or notdepends on its response to foreign matters.Facing the increasing amount and diversi-ty of chemicals, natural and synthetic, tounderstand the ...I. THE COMPLEXITY OFBIOLOGICAL RESPONSESFor an organism, to be living or notdepends on its response to foreign matters.Facing the increasing amount and diversi-ty of chemicals, natural and synthetic, tounderstand the principles of the biologicalresponses becomes extremely importantin pursuing the way of rational utiliza-tion and governing the foreign matters.However, most biological responses aretoo complex to explore their nature. Forinstance, the risk to human beings andorganisms related to the application ofrare earths in agriculture, forestation, fish-ery and husbandry has been argued展开更多
Starting from the supposition of time-space substitution, the Langbein-Schumm's Law was applied to deal with response of fluvial erosion System to the changes in mean annual Precipitation induced by global green-h...Starting from the supposition of time-space substitution, the Langbein-Schumm's Law was applied to deal with response of fluvial erosion System to the changes in mean annual Precipitation induced by global green-house warming. As a result, a simple method was put forward to predict change in sediment yield, with Ningxia Hui Autonomous Region in the northern fringe of the Loess Plateau of China as an example. Results show that, even the change in mean annual precipitation is the same, the direction and magnitude of the resultant chang in sediment yteld would be quite different in fferent physico-geographical zones. When mean annual precipitation is increased, sediment yield in arid or semi-arid areas with a mean anntal Peripitation of less than 400 mm will be increased, while sediment yield in sub-humid or humid areas with a mean annual precipitation of more than 400 mm will be decreased.Additionally, the complex response of fluvial erosion system in time series due to the lag of change in vegetation behind the changn in precipitation has also been qualitatively discussed in this paper.展开更多
Sensing of analyte s in biological fluids and biotechnological production media remains a challenge.He re,the luminescent response of the europium(Ⅲ)complex of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid(DO3A...Sensing of analyte s in biological fluids and biotechnological production media remains a challenge.He re,the luminescent response of the europium(Ⅲ)complex of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid(DO3A)to bicarbonate was investigated in detail.The response of Eu.DO3A to changes in bicarbonate concentration was studied in different buffers,and the influence of ionic strength,pH,and specific ions was determined.The response is found to depend on pH and ionic strength,but it is not possible to separate contributions from the sensing event from those in the bicarbonate activity.Prior to demonstrating the ability to determine the bicarbonate concentration in bioproduction media and serum,the influence of competing carboxy anions was evaluated.It is established that while competing anions bind stronger to the responsive complex,at the relevant concentration their contribution to the recorded signal is negligible.We are thus able to conclude that Eu.DO3A is a good platform for building a bicarbonate sensor.展开更多
A novel supramolecular graft copolymer （SGP） composed of viologen-containing copolymer （P（DMA-co- diEV）） as the main chain and Np ended PNIPAM （Np-PNIPAm） as the grafts is prepared （DMA： N,N- dimethylacryami...A novel supramolecular graft copolymer （SGP） composed of viologen-containing copolymer （P（DMA-co- diEV）） as the main chain and Np ended PNIPAM （Np-PNIPAm） as the grafts is prepared （DMA： N,N- dimethylacryamide, diEV： ethylviologen dimer, Np： naphthalene, PNIPAM： poly（N-isopropylacrylamide））. The grafting is based on the triple complexation among a host of cucurbit[8]uril （CB[8]） and two vips of diEV and Np, which is characterized by UV-vis spectra and ITC. Temperature sensitive property of PNIPAm moiety allows SGP to self-assemble into non-covalently connected micelle （NCCM） at high temperature. The micelles are sensitive to reducing agents, for example Na2S203, which breaks the current inclusion complex pair and induces aggregation.展开更多
文摘I. THE COMPLEXITY OFBIOLOGICAL RESPONSESFor an organism, to be living or notdepends on its response to foreign matters.Facing the increasing amount and diversi-ty of chemicals, natural and synthetic, tounderstand the principles of the biologicalresponses becomes extremely importantin pursuing the way of rational utiliza-tion and governing the foreign matters.However, most biological responses aretoo complex to explore their nature. Forinstance, the risk to human beings andorganisms related to the application ofrare earths in agriculture, forestation, fish-ery and husbandry has been argued
文摘Starting from the supposition of time-space substitution, the Langbein-Schumm's Law was applied to deal with response of fluvial erosion System to the changes in mean annual Precipitation induced by global green-house warming. As a result, a simple method was put forward to predict change in sediment yield, with Ningxia Hui Autonomous Region in the northern fringe of the Loess Plateau of China as an example. Results show that, even the change in mean annual precipitation is the same, the direction and magnitude of the resultant chang in sediment yteld would be quite different in fferent physico-geographical zones. When mean annual precipitation is increased, sediment yield in arid or semi-arid areas with a mean anntal Peripitation of less than 400 mm will be increased, while sediment yield in sub-humid or humid areas with a mean annual precipitation of more than 400 mm will be decreased.Additionally, the complex response of fluvial erosion system in time series due to the lag of change in vegetation behind the changn in precipitation has also been qualitatively discussed in this paper.
基金Project supported by the University of Copenhagen,the Novo Nordisk Foundation(grant number 4096)Carlsbergfondet,the Villum Foundation(grant number 14922)ENS Lyon。
文摘Sensing of analyte s in biological fluids and biotechnological production media remains a challenge.He re,the luminescent response of the europium(Ⅲ)complex of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid(DO3A)to bicarbonate was investigated in detail.The response of Eu.DO3A to changes in bicarbonate concentration was studied in different buffers,and the influence of ionic strength,pH,and specific ions was determined.The response is found to depend on pH and ionic strength,but it is not possible to separate contributions from the sensing event from those in the bicarbonate activity.Prior to demonstrating the ability to determine the bicarbonate concentration in bioproduction media and serum,the influence of competing carboxy anions was evaluated.It is established that while competing anions bind stronger to the responsive complex,at the relevant concentration their contribution to the recorded signal is negligible.We are thus able to conclude that Eu.DO3A is a good platform for building a bicarbonate sensor.
基金Ministry of Science and Technology of China(Nos. 2011CB932503 and 2009CB930402)National Natural Science Foundation of China(No.91227203) are acknowledged for their financial support
文摘A novel supramolecular graft copolymer （SGP） composed of viologen-containing copolymer （P（DMA-co- diEV）） as the main chain and Np ended PNIPAM （Np-PNIPAm） as the grafts is prepared （DMA： N,N- dimethylacryamide, diEV： ethylviologen dimer, Np： naphthalene, PNIPAM： poly（N-isopropylacrylamide））. The grafting is based on the triple complexation among a host of cucurbit[8]uril （CB[8]） and two vips of diEV and Np, which is characterized by UV-vis spectra and ITC. Temperature sensitive property of PNIPAm moiety allows SGP to self-assemble into non-covalently connected micelle （NCCM） at high temperature. The micelles are sensitive to reducing agents, for example Na2S203, which breaks the current inclusion complex pair and induces aggregation.
