Tailings produced by mining and ore smelting are a major source of soil pollution.Understanding the speciation of heavy metals(HMs)in tailings is essential for soil remediation and sustainable development.Given the co...Tailings produced by mining and ore smelting are a major source of soil pollution.Understanding the speciation of heavy metals(HMs)in tailings is essential for soil remediation and sustainable development.Given the complex and time-consuming nature of traditional sequential laboratory extraction methods for determining the forms of HMs in tailings,a rapid and precise identification approach is urgently required.To address this issue,a general empirical prediction method for HM occurrence was developed using machine learning(ML).The compositional information of the tailings,properties of the HMs,and sequential extraction steps were used as inputs to calculate the percentages of the seven forms of HMs.After the models were tuned and compared,extreme gradient boosting,gradient boosting decision tree,and categorical boosting methods were found to be the top three performing ML models,with the coefficient of determination(R^(2))values on the testing set exceeding 0.859.Feature importance analysis for these three optimal models indicated that electronegativity was the most important factor affecting the occurrence of HMs,with an average feature importance of 0.4522.The subsequent use of stacking as a model integration method enabled the ability of the ML models to predict HM occurrence forms to be further improved,and resulting in an increase of R^(2) to 0.879.Overall,this study developed a robust technique for predicting the occurrence forms in tailings and provides an important reference for the environmental assessment and recycling of tailings.展开更多
The NEutron Detector Array(NEDA)is designed to be coupled to gamma-ray spectrometers to enhance the sensitivity of the setup by enabling reaction channel selection through counting of the evaporated neutrons.This arti...The NEutron Detector Array(NEDA)is designed to be coupled to gamma-ray spectrometers to enhance the sensitivity of the setup by enabling reaction channel selection through counting of the evaporated neutrons.This article presents the implementation of a double trigger condition system for NEDA,which improves the acquisition of neutrons and reduces the number of gamma rays acquired.Two independent triggers are generated in the double trigger condition system:one based on charge comparison(CC)and the other on time-of-flight(TOF).These triggers can be combined using OR and AND logic,offering four distinct trigger modes.The developed firmware is added to the previous one in the Virtex 6 field programmable gate array(FPGA)present in the system,which also includes signal processing,baseline correction,and various trigger logic blocks.The performance of the trigger system is evaluated using data from the E703 experiment performed at GANIL.The four trigger modes are applied to the same data,and a subsequent offline analysis is performed.It is shown that most of the detected neutrons are preserved with the AND mode,and the total number of gamma rays is significantly reduced.Compared with the CC trigger mode,the OR trigger mode allows increasing the selection of neutrons.In addition,it is demonstrated that if the OR mode is selected,the online CC trigger threshold can be raised without losing neutrons.展开更多
To address the installation challenges of a 2-m ring Gregorian telescope system,and similar optical systems with a small width-to-radius ratio,we propose a detection method combining local interferometry with a compar...To address the installation challenges of a 2-m ring Gregorian telescope system,and similar optical systems with a small width-to-radius ratio,we propose a detection method combining local interferometry with a comparison model.This method enhances the precision of system calibration by establishing a dataset that delineates the relationship between secondary mirror misalignment and wavefront aberration,subsequently inferring the misalignment from interferometric detection results during the calibration process.For the 2-m ring telescope,we develop a detection model using five local sub-apertures,enabling a root-mean-square detection accuracy of 0:0225λ(λ=632:8 nm)for full-aperture wavefront aberration.The calibration results for the 2-m Ring Solar Telescope system indicate that the root-mean-square value of sub-aperture wavefront aberration reaches 0.104λ,and the root-mean-square value of spliced full-aperture measurement yields reaches 0.112λ.This method offers a novel approach for calibrating small width-toradius ratio telescope systems and can be applied to the calibration of other irregular-aperture optical systems.展开更多
Multi-firmware comparison techniques can improve efficiency when auditing firmwares in bulk.How-ever,the problem of matching functions between multiple firmwares has not been studied before.This paper proposes a multi...Multi-firmware comparison techniques can improve efficiency when auditing firmwares in bulk.How-ever,the problem of matching functions between multiple firmwares has not been studied before.This paper proposes a multi-firmware comparison method based on evolutionary algorithms and trusted base points.We first model the multi-firmware comparison as a multi-sequence matching problem.Then,we propose an adaptation function and a population generation method based on trusted base points.Finally,we apply an evolutionary algorithm to find the optimal result.At the same time,we design the similarity of matching results as an evaluation metric to measure the effect of multi-firmware comparison.The experiments show that the proposed method outperforms Bindiff and the string-based method.Precisely,the similarity between the matching results of the proposed method and Bindiff matching results is 61%,and the similarity between the matching results of the proposed method and the string-based method is 62.8%.By sampling and manual verification,the accuracy of the matching results of the proposed method can be about 66.4%.展开更多
Given that the citrus psyllid is the primary vector of citrus Huanglongbing(HLB),there is an urgent need to control this pest to mitigate the spread of the disease.This paper reviews the current research on two predom...Given that the citrus psyllid is the primary vector of citrus Huanglongbing(HLB),there is an urgent need to control this pest to mitigate the spread of the disease.This paper reviews the current research on two predominant control strategies:chemical control and biological control agents,in managing the citrus psyllid.It emphasizes the mechanisms of action,efficacy,and application advancements of these control methods.Finally,the paper analyzes the principal challenges associated with the sustainable management of citrus psyllids and offers perspectives for future research.展开更多
BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an essential diagnostic and therapeutic procedure for pancreatobiliary disorders.However,few large-scale studies from South Asia have examined long-ter...BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an essential diagnostic and therapeutic procedure for pancreatobiliary disorders.However,few large-scale studies from South Asia have examined long-term ERCP outcomes,particularly using established quality benchmarks.AIM To evaluate ERCP indications,success rates,complications,and quality performance at a high-volume tertiary care center in Pakistan over a 17-year period.METHODS This retrospective study analyzed 13215 ERCP procedures performed between 2006 and 2023.Data included demographics,indications,cannulation rates,complications,and pediatric cases.Findings were assessed against American Society of Gastroenterology/European Society of Gastrointestinal Endoscopy quality indicators.RESULTS Biliary ERCP accounted for 93.1%of procedures;choledocholithiasis was the most common indication(40%).Cannulation success was 93.9%for biliary and 94.2%for pancreatic ERCP.Pediatric ERCP comprised 4%of cases,mostly for stones and chronic pancreatitis.Bleeding(1.7%)and post-ERCP pancreatitis(2.3%)were the most frequent complications.Performance met or exceeded most American Society of Benchmarks.CONCLUSION This study offers insight into nearly two decades of ERCP practice within a public sector hospital.Our experience echoes the quality and efficiency of ERCP not previously available in Pakistan.As healthcare systems in resourcelimited sectors expand,our findings serve as a reference point.Continued training and quality improvement studies can further enhance ERCP effectiveness in the region and beyond.展开更多
Previous bidirectional quantum private comparison(BQPC)protocols cannot meet the requirements in some special application scenarios,where only one party needs to obtain the comparison results without a third party(TP)...Previous bidirectional quantum private comparison(BQPC)protocols cannot meet the requirements in some special application scenarios,where only one party needs to obtain the comparison results without a third party(TP),such as scenarios for authority surveys or healthcare data sharing.In addition to this,the BQPC protocol has the potential of information leakage in multiple comparisons.Therefore,we design a new unidirectional quantum private comparison(UQPC)protocol based on quantum private query(QPQ)protocols with ideal database security and zero failure probability(IDS-ZF),for the reason that they have excellent unidirectionality and security.Concretely,we design a UQPC protocol based on Wei et al.’s work[IEEE Transactions on Computers 672(2017)]and it includes an authentication process to increase the resistance to outside attacks.Moreover,we generalize the protocol and propose a general model that can transform a QPQ protocol with or without the IDS-ZF property into a secure UQPC protocol.Finally,our study shows that protocols using our model are secure,practical,and have the IDS-ZF property.展开更多
This paper focuses on the service management for digitally disadvantaged groups in Chinese and American public libraries.Utilizing a comparative analysis method,it explores the differences and dilemmas between the two...This paper focuses on the service management for digitally disadvantaged groups in Chinese and American public libraries.Utilizing a comparative analysis method,it explores the differences and dilemmas between the two countries in terms of policy support,resource allocation,service models,and librarian training.The research finds that the United States has established a relatively comprehensive legal guarantee system and diverse funding channels,but recent federal policy fluctuations pose risks to project sustainability.Although China has made significant progress in equalizing services,it still faces structural challenges such as insufficient institutional guarantees and uneven resource allocation.Based on the comparative analysis,this paper proposes strategic suggestions including establishing a four-dimensional support system of"Law-Resources-Technology-Personnel"and promoting a"Digital Inclusion Partnership"model,aiming to provide references for Chinese public libraries to improve services for digitally disadvantaged groups.展开更多
Driven by rapid technological advancements and economic growth,mineral extraction and metal refining have increased dramatically,generating huge volumes of tailings and mine waste(TMWs).Investigating the morphological...Driven by rapid technological advancements and economic growth,mineral extraction and metal refining have increased dramatically,generating huge volumes of tailings and mine waste(TMWs).Investigating the morphological fractions of heavy metals and metalloids(HMMs)in TMWs is key to evaluating their leaching potential into the environment;however,traditional experiments are time-consuming and labor-intensive.In this study,10 machine learning(ML)algorithms were used and compared for rapidly predicting the morphological fractions of HMMs in TMWs.A dataset comprising 2376 data points was used,with mineral composition,elemental properties,and total concentration used as inputs and concentration of morphological fraction used as output.After grid search optimization,the extra tree model performed the best,achieving coefficient of determination(R2)of 0.946 and 0.942 on the validation and test sets,respectively.Electronegativity was found to have the greatest impact on the morphological fraction.The models’performance was enhanced by applying an ensemble method to the top three optimal ML models,including gradient boosting decision tree,extra trees and categorical boosting.Overall,the proposed framework can accurately predict the concentrations of different morphological fractions of HMMs in TMWs.This approach can minimize detection time,aid in the safe management and recovery of TMWs.展开更多
BACKGROUND Recently,there has been a significant increase in the consumption of ultraprocessed foods worldwide.However,the association between the consumption of ultra-processed food,obesity,and the prevalence of colo...BACKGROUND Recently,there has been a significant increase in the consumption of ultraprocessed foods worldwide.However,the association between the consumption of ultra-processed food,obesity,and the prevalence of colon cancer remains controversial.AIM To find out the association between the consumption of ultra-processed food,obesity,and the prevalence of colon cancer.METHODS A comprehensive systematic literature search of PubMed,Scopus,Web of Science,and Google Scholar for grey literature was done for articles published before 8th March 2023.The search was done to retrieve potential peer-reviewed articles that explored the association between the consumption of ultra-processed food,obesity,and the prevalence of colon cancer.RESULTS Of the 246 potential articles assessed,17 met the inclusion criteria.Meta-analysis results demonstrated that high consumption of ultra-processed food is associated with an increased risk of obesity[odds ratio(OR):1.65;95%CI:1.07-2.45;P<0.05].Consequently,there is a positive association between obesity and an increased risk of colon cancer(OR 1.48;95%CI:0.77-2.87;P>0.05).CONCLUSION Consuming ultra-processed foods increases the risk of obesity and colon cancer.展开更多
State-of-the-art technologies such as the Internet of Things(IoT),cloud computing(CC),big data analytics(BDA),and artificial intelligence(AI)have greatly stimulated the development of smart manufacturing.An important ...State-of-the-art technologies such as the Internet of Things(IoT),cloud computing(CC),big data analytics(BDA),and artificial intelligence(AI)have greatly stimulated the development of smart manufacturing.An important prerequisite for smart manufacturing is cyber-physical integration,which is increasingly being embraced by manufacturers.As the preferred means of such integration,cyber-physical systems(CPS)and digital twins(DTs)have gained extensive attention from researchers and practitioners in industry.With feedback loops in which physical processes affect cyber parts and vice versa,CPS and DTs can endow manufacturing systems with greater efficiency,resilience,and intelligence.CPS and DTs share the same essential concepts of an intensive cyber-physical connection,real-time interaction,organization integration,and in-depth collaboration.However,CPS and DTs are not identical from many perspectives,including their origin,development,engineering practices,cyber-physical mapping,and core elements.In order to highlight the differences and correlation between them,this paper reviews and analyzes CPS and DTs from multiple perspectives.展开更多
This study was designed to evaluate the efficacy, tolerability, and sequential administration of abiraterone acetate （AA） and enzalutamide （Enz） for metastatic castration-resistant prostate cancer （mCRPC）. A lit...This study was designed to evaluate the efficacy, tolerability, and sequential administration of abiraterone acetate （AA） and enzalutamide （Enz） for metastatic castration-resistant prostate cancer （mCRPC）. A literature search was performed with PubMed, Embase, and Web of Science databases to identify relevant studies. Reviewed literature included published phase III trials of AA or Enz in mCRPC and studies regarding their sequential administration. Given the difference in control arms in AA （active comparator） and Enz （true placebo） randomized phase III studies, indirect comparisons between AA and Enz in mCRPC showed no statistically significant difference in overall survival in prechemotherapy and postchemotherapy settings （HR. 0.90, 95% CI, 0.73-1.11; HR： 0.85, 95% CI, 0.68-1.07）. Compared with AA, Enz may better outperform control arms in treating mCRPC both before and after chemotherapy regarding secondary endpoints based on indirect comparisons： time to prostate-specific antigen （PSA） progression （HR. 0.34, 95% CI, 0.28-0.42; HR： 0.40, 95% CI, 0.30-0.53）, radiographic progression-free survival （HR： 0.37, 95% CI, 0.28-0.48; HR： 0.61, 95% CI, 0.50-0.74）, and PSA response rate （OR： 18.29, 95% CI, 11.20-29.88; OR： 10.69, 95% CI, 3.92-29.20）. With regard to the effectiveness of Enz following AA or AA following Enz, recent retrospective case series reported overall survival and secondary endpoints for patients with mCRPC progression after chemotherapy. However, confirmatory head-to-head trials are necessary to determine the optimal sequencing of these agents.展开更多
In the future, solar energy will be a very important energy source. Several studies suppose that more than 45% of the energy in the world will be generated by photovoltaic array. Therefore it is necessary to concentra...In the future, solar energy will be a very important energy source. Several studies suppose that more than 45% of the energy in the world will be generated by photovoltaic array. Therefore it is necessary to concentrate our forces to reduce the application costs and to increment their performance. In order to reach the last aspect, it is important to note that the output characteristic of a photovoltaic array is nonlinear and changes with solar irradiation and cell’s temperature. Therefore a Maximum Power Point Tracking (MPPT) technique is needed to maximize the produced energy. This paper presents a comparative study of seven widely-adopted MPPT algorithms;their performance is evaluated using, for all the techniques, a common device with minimum hardware variations. In particular, this study compares the behaviors of each technique in presence of solar irradiation variations.展开更多
Twelve healthy rats were divided into the T-2 toxin group receiving gavage of 1 mg/kg T-2 toxin and the control group receiving gavage of normal saline. Total relative concentrations of T-2 toxin and HT-2 toxin in the...Twelve healthy rats were divided into the T-2 toxin group receiving gavage of 1 mg/kg T-2 toxin and the control group receiving gavage of normal saline. Total relative concentrations of T-2 toxin and HT-2 toxin in the skeletal system（thighbone, knee joints, and costal cartilage） were significantly higher than those in the heart, liver, and kidneys（P 〈 0.05）. The relative concentrations of T-2 toxin and HT-2 toxin in the skeletal system（thighbone and costal cartilage） were also significantly higher than those in the heart, liver, and kidneys. The rats administered T-2 toxin showed rapid metabolism compared with that in rats administered HT-2 toxin, and the metabolic conversion rates in the different tissues were 68.20%-90.70%.展开更多
The paper gives a brief description about the current main forest fire danger rating systems in the world, which in- clude forest fire danger rating system used in Canada, USA, Australia, and other countries. It show...The paper gives a brief description about the current main forest fire danger rating systems in the world, which in- clude forest fire danger rating system used in Canada, USA, Australia, and other countries. It shows the composition, structure and development of the main fire danger rating systems. The limitations of those systems are also discussed. Through a comparison of the three main forest fire danger rating systems the paper describes their differences on development, fuel complex descriptions, inputs and outputs, and their applications and finds that the technologies of the Canadian forest fire danger rating system can be adopted for China to develop a national forest fire danger rating system. Two steps are needed to develop our own national forest fire danger rating system. Firstly, we apply the CFFDRS directly. Then some studies should be done to calibrate the FDRS to local weather and fuel characteristics.展开更多
BACKGROUND Gastritis is one of the most frequently diagnosed diseases requiring medical treatment in South Korea.Fexuprazan,a novel potassium-competitive acid blocker,has been approved for treating gastritis and erosi...BACKGROUND Gastritis is one of the most frequently diagnosed diseases requiring medical treatment in South Korea.Fexuprazan,a novel potassium-competitive acid blocker,has been approved for treating gastritis and erosive esophagitis.Meanwhile,rebamipide is the most commonly used mucoprotective agent for acute and chronic gastritis in real-world settings in South Korea.However,there have been no studies comparing the efficacy of these two drugs yet.AIM To compare the efficacy of fexuprazan with that of rebamipide for acute and chronic gastritis.METHODS This was a matching-adjusted indirect comparison.Individual patient data from a phase III study of fexuprazan(10 mg BID)were compared with cumulative data from two matching studies of rebamipide(100 mg TID).Erosion improvement and healing rates were compared between two weeks of fexurapan,two weeks of rebamipide,and four weeks of rebamipide.The two main outcome variables were presented as percentages,and the risk differences(RD)and 95%confidence intervals(CI)were calculated for the relative treatment effects.RESULTS In the primary analysis,the erosion improvement and healing rates after a twoweek treatment with fexuprazan were 64.5%and 53.2%,respectively,while a twoweek treatment with rebamipide resulted in erosion improvement and healing rates of 43.6%(RD:21.0%;95%CI:9.6-32.3;P<0.01)and 35.6%(RD:17.6%;95%CI:6.1-29.2;P=0.003),respectively.In the additional analysis,the erosion improvement and healing rates for the two-week fexuprazan treatment(64.2%and 51.2%,respectively)were similar to those obtained during a four-week treatment with rebamipide(60.6%;RD:3.6%;95%CI:-9.8,17.0;P=0.600 and 53.5%;RD:-2.3%;95%CI:-16.1,11.5;P=0.744,respectively).CONCLUSION The two-week fexuprazan treatment was superior to the two-week rebamipide treatment and similar to the fourweek rebamipide treatment for patients with gastritis.展开更多
Food is the paramount necessity of the people,and safety is most essential for food. Food safety is related to people's fundamental interests,affecting people's basic health. It is an important factor in promo...Food is the paramount necessity of the people,and safety is most essential for food. Food safety is related to people's fundamental interests,affecting people's basic health. It is an important factor in promoting people's livelihood development and social progress. Compared with European countries and the United States in developed food safety supervision systems,the development of food safety supervision system in China is still relatively backward. As food safety supervision is not in place,food safety incidents have occurred in recent years,so that public's panic about food safety has intensified. It has a strong impact on social stability and the food economy. Thus,strengthening the construction of food safety supervision system is imperative. Since experiencing a series of food safety incidents,the EU has gradually improved its food safety supervision system and has developed the most comprehensive and mature food safety supervision system in the world. On the basis of sorting out the characteristics of EU's food safety supervision system,the development direction of China's food safety supervision system is proposed from four aspects: supervisor,legal system,law enforcement ability and safety standards.展开更多
The time optimal problem for a two level quantum sys-tem is studied. We compare two different control strategies of bang-bang control and the geometric control, respectively, es-pecial y in the case of minimizing the ...The time optimal problem for a two level quantum sys-tem is studied. We compare two different control strategies of bang-bang control and the geometric control, respectively, es-pecial y in the case of minimizing the time of steering the state from North Pole to South Pole on the Bloch sphere with bounded control. The time performances are compared for different param-eters by the individual numerical simulation experiments, and the experimental results are analyzed. The results show that the ge-ometric control spends less time than the bang-bang control does.展开更多
We compare three different methods to extract coherent modes from Doppler backscattering （DBS）, which are center of gravity （COG） of the complex amplitude spectrum, spectrum of DBS phase derivative （phase derivat...We compare three different methods to extract coherent modes from Doppler backscattering （DBS）, which are center of gravity （COG） of the complex amplitude spectrum, spectrum of DBS phase derivative （phase derivative method）, and phase spectrum, respectively. These three methods are all feasible to extract coherent modes, for example, geodesic acoustic mode oscillation. However, there are stilI differences between dealing with high frequency modes （several hundred kHz） and low frequency modes, （several kHz） hiding in DBS signal. There is a significant amount of power at low frequencies in the phase spectrum, which can be removed by using the phase derivative method and COG. High frequency modes are clearer by using the COO and the phase derivative method than the phase spectrum. The spectrum of DBS amplitude does not show the coherent modes detected by using COG, phase derivative method and phase spectrum. When two Doppler shifted peaks exist, coherent modes and their harmonics appear in the spectrum of DBS amplitude, which are introduced by the DBS phase.展开更多
基金financially supported by the Natural Science Foundation of Hunan Province,China(No.2024JJ2074)the National Natural Science Foundation of China(No.22376221)the Young Elite Scientists Sponsorship Program by CAST,China(No.2023QNRC001).
文摘Tailings produced by mining and ore smelting are a major source of soil pollution.Understanding the speciation of heavy metals(HMs)in tailings is essential for soil remediation and sustainable development.Given the complex and time-consuming nature of traditional sequential laboratory extraction methods for determining the forms of HMs in tailings,a rapid and precise identification approach is urgently required.To address this issue,a general empirical prediction method for HM occurrence was developed using machine learning(ML).The compositional information of the tailings,properties of the HMs,and sequential extraction steps were used as inputs to calculate the percentages of the seven forms of HMs.After the models were tuned and compared,extreme gradient boosting,gradient boosting decision tree,and categorical boosting methods were found to be the top three performing ML models,with the coefficient of determination(R^(2))values on the testing set exceeding 0.859.Feature importance analysis for these three optimal models indicated that electronegativity was the most important factor affecting the occurrence of HMs,with an average feature importance of 0.4522.The subsequent use of stacking as a model integration method enabled the ability of the ML models to predict HM occurrence forms to be further improved,and resulting in an increase of R^(2) to 0.879.Overall,this study developed a robust technique for predicting the occurrence forms in tailings and provides an important reference for the environmental assessment and recycling of tailings.
基金supported by MICIU MCIN/AEI/10.13039/501100011033Spain with Grant PID2020-118265GB-C42,-C44,PRTR-C17.I01Generalitat Valenciana,Spain with Grant CIPROM/2022/54,ASFAE/2022/031,CIAPOS/2021/114 and by the EU NextGenerationEU,ESF funds.This work was also supported by the National Science Centre(NCN),Poland(Grant No.2020/39/D/ST2/00466).
文摘The NEutron Detector Array(NEDA)is designed to be coupled to gamma-ray spectrometers to enhance the sensitivity of the setup by enabling reaction channel selection through counting of the evaporated neutrons.This article presents the implementation of a double trigger condition system for NEDA,which improves the acquisition of neutrons and reduces the number of gamma rays acquired.Two independent triggers are generated in the double trigger condition system:one based on charge comparison(CC)and the other on time-of-flight(TOF).These triggers can be combined using OR and AND logic,offering four distinct trigger modes.The developed firmware is added to the previous one in the Virtex 6 field programmable gate array(FPGA)present in the system,which also includes signal processing,baseline correction,and various trigger logic blocks.The performance of the trigger system is evaluated using data from the E703 experiment performed at GANIL.The four trigger modes are applied to the same data,and a subsequent offline analysis is performed.It is shown that most of the detected neutrons are preserved with the AND mode,and the total number of gamma rays is significantly reduced.Compared with the CC trigger mode,the OR trigger mode allows increasing the selection of neutrons.In addition,it is demonstrated that if the OR mode is selected,the online CC trigger threshold can be raised without losing neutrons.
基金supported by the Jiangsu Provincial Key Research and Development Program(BE2022072)the National Natural Science Foundation of China(12141304)the Natural Science Foundation of Jiangsu Province(BK20231134).
文摘To address the installation challenges of a 2-m ring Gregorian telescope system,and similar optical systems with a small width-to-radius ratio,we propose a detection method combining local interferometry with a comparison model.This method enhances the precision of system calibration by establishing a dataset that delineates the relationship between secondary mirror misalignment and wavefront aberration,subsequently inferring the misalignment from interferometric detection results during the calibration process.For the 2-m ring telescope,we develop a detection model using five local sub-apertures,enabling a root-mean-square detection accuracy of 0:0225λ(λ=632:8 nm)for full-aperture wavefront aberration.The calibration results for the 2-m Ring Solar Telescope system indicate that the root-mean-square value of sub-aperture wavefront aberration reaches 0.104λ,and the root-mean-square value of spliced full-aperture measurement yields reaches 0.112λ.This method offers a novel approach for calibrating small width-toradius ratio telescope systems and can be applied to the calibration of other irregular-aperture optical systems.
文摘Multi-firmware comparison techniques can improve efficiency when auditing firmwares in bulk.How-ever,the problem of matching functions between multiple firmwares has not been studied before.This paper proposes a multi-firmware comparison method based on evolutionary algorithms and trusted base points.We first model the multi-firmware comparison as a multi-sequence matching problem.Then,we propose an adaptation function and a population generation method based on trusted base points.Finally,we apply an evolutionary algorithm to find the optimal result.At the same time,we design the similarity of matching results as an evaluation metric to measure the effect of multi-firmware comparison.The experiments show that the proposed method outperforms Bindiff and the string-based method.Precisely,the similarity between the matching results of the proposed method and Bindiff matching results is 61%,and the similarity between the matching results of the proposed method and the string-based method is 62.8%.By sampling and manual verification,the accuracy of the matching results of the proposed method can be about 66.4%.
基金Supported by National Undergraduate Training Programs for Innovation and Entrepreneurship(202510580009)Special Project for Promoting the Coordinated Development of Urban and Rural Areas and Regions by Introducing Scientific and Technological Achievements of Guangdong Province into Counties and Towns(2025B0202010051)Project of High-quality Development in Hundred Counties,Thousands Towns and Ten Thousand Villages of Guangdong Provincial Department of Science and Technology:Key Dispatch Project for Rural Science and Technology Commissioners(KTP20240704).
文摘Given that the citrus psyllid is the primary vector of citrus Huanglongbing(HLB),there is an urgent need to control this pest to mitigate the spread of the disease.This paper reviews the current research on two predominant control strategies:chemical control and biological control agents,in managing the citrus psyllid.It emphasizes the mechanisms of action,efficacy,and application advancements of these control methods.Finally,the paper analyzes the principal challenges associated with the sustainable management of citrus psyllids and offers perspectives for future research.
文摘BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an essential diagnostic and therapeutic procedure for pancreatobiliary disorders.However,few large-scale studies from South Asia have examined long-term ERCP outcomes,particularly using established quality benchmarks.AIM To evaluate ERCP indications,success rates,complications,and quality performance at a high-volume tertiary care center in Pakistan over a 17-year period.METHODS This retrospective study analyzed 13215 ERCP procedures performed between 2006 and 2023.Data included demographics,indications,cannulation rates,complications,and pediatric cases.Findings were assessed against American Society of Gastroenterology/European Society of Gastrointestinal Endoscopy quality indicators.RESULTS Biliary ERCP accounted for 93.1%of procedures;choledocholithiasis was the most common indication(40%).Cannulation success was 93.9%for biliary and 94.2%for pancreatic ERCP.Pediatric ERCP comprised 4%of cases,mostly for stones and chronic pancreatitis.Bleeding(1.7%)and post-ERCP pancreatitis(2.3%)were the most frequent complications.Performance met or exceeded most American Society of Benchmarks.CONCLUSION This study offers insight into nearly two decades of ERCP practice within a public sector hospital.Our experience echoes the quality and efficiency of ERCP not previously available in Pakistan.As healthcare systems in resourcelimited sectors expand,our findings serve as a reference point.Continued training and quality improvement studies can further enhance ERCP effectiveness in the region and beyond.
基金supported by the National Key Research and Development Program of China(Grant Nos.2024YFB2906504 and 2024YFB2906500)the National Natural Science Foundation of China(Grant Nos.62401067 and 62272051)the 111 Project(Grant No.B21049).
文摘Previous bidirectional quantum private comparison(BQPC)protocols cannot meet the requirements in some special application scenarios,where only one party needs to obtain the comparison results without a third party(TP),such as scenarios for authority surveys or healthcare data sharing.In addition to this,the BQPC protocol has the potential of information leakage in multiple comparisons.Therefore,we design a new unidirectional quantum private comparison(UQPC)protocol based on quantum private query(QPQ)protocols with ideal database security and zero failure probability(IDS-ZF),for the reason that they have excellent unidirectionality and security.Concretely,we design a UQPC protocol based on Wei et al.’s work[IEEE Transactions on Computers 672(2017)]and it includes an authentication process to increase the resistance to outside attacks.Moreover,we generalize the protocol and propose a general model that can transform a QPQ protocol with or without the IDS-ZF property into a secure UQPC protocol.Finally,our study shows that protocols using our model are secure,practical,and have the IDS-ZF property.
文摘This paper focuses on the service management for digitally disadvantaged groups in Chinese and American public libraries.Utilizing a comparative analysis method,it explores the differences and dilemmas between the two countries in terms of policy support,resource allocation,service models,and librarian training.The research finds that the United States has established a relatively comprehensive legal guarantee system and diverse funding channels,but recent federal policy fluctuations pose risks to project sustainability.Although China has made significant progress in equalizing services,it still faces structural challenges such as insufficient institutional guarantees and uneven resource allocation.Based on the comparative analysis,this paper proposes strategic suggestions including establishing a four-dimensional support system of"Law-Resources-Technology-Personnel"and promoting a"Digital Inclusion Partnership"model,aiming to provide references for Chinese public libraries to improve services for digitally disadvantaged groups.
基金Project(2024JJ2074) supported by the Natural Science Foundation of Hunan Province,ChinaProject(22376221) supported by the National Natural Science Foundation of ChinaProject(2023QNRC001) supported by the Young Elite Scientists Sponsorship Program by CAST,China。
文摘Driven by rapid technological advancements and economic growth,mineral extraction and metal refining have increased dramatically,generating huge volumes of tailings and mine waste(TMWs).Investigating the morphological fractions of heavy metals and metalloids(HMMs)in TMWs is key to evaluating their leaching potential into the environment;however,traditional experiments are time-consuming and labor-intensive.In this study,10 machine learning(ML)algorithms were used and compared for rapidly predicting the morphological fractions of HMMs in TMWs.A dataset comprising 2376 data points was used,with mineral composition,elemental properties,and total concentration used as inputs and concentration of morphological fraction used as output.After grid search optimization,the extra tree model performed the best,achieving coefficient of determination(R2)of 0.946 and 0.942 on the validation and test sets,respectively.Electronegativity was found to have the greatest impact on the morphological fraction.The models’performance was enhanced by applying an ensemble method to the top three optimal ML models,including gradient boosting decision tree,extra trees and categorical boosting.Overall,the proposed framework can accurately predict the concentrations of different morphological fractions of HMMs in TMWs.This approach can minimize detection time,aid in the safe management and recovery of TMWs.
文摘BACKGROUND Recently,there has been a significant increase in the consumption of ultraprocessed foods worldwide.However,the association between the consumption of ultra-processed food,obesity,and the prevalence of colon cancer remains controversial.AIM To find out the association between the consumption of ultra-processed food,obesity,and the prevalence of colon cancer.METHODS A comprehensive systematic literature search of PubMed,Scopus,Web of Science,and Google Scholar for grey literature was done for articles published before 8th March 2023.The search was done to retrieve potential peer-reviewed articles that explored the association between the consumption of ultra-processed food,obesity,and the prevalence of colon cancer.RESULTS Of the 246 potential articles assessed,17 met the inclusion criteria.Meta-analysis results demonstrated that high consumption of ultra-processed food is associated with an increased risk of obesity[odds ratio(OR):1.65;95%CI:1.07-2.45;P<0.05].Consequently,there is a positive association between obesity and an increased risk of colon cancer(OR 1.48;95%CI:0.77-2.87;P>0.05).CONCLUSION Consuming ultra-processed foods increases the risk of obesity and colon cancer.
基金This work is financially supported by the National Key Research and Development Program of China(2016YFB1101700)the National Natural Science Foundation of China(51875030)the Academic Excellence Foundation of BUAA for PhD Students.
文摘State-of-the-art technologies such as the Internet of Things(IoT),cloud computing(CC),big data analytics(BDA),and artificial intelligence(AI)have greatly stimulated the development of smart manufacturing.An important prerequisite for smart manufacturing is cyber-physical integration,which is increasingly being embraced by manufacturers.As the preferred means of such integration,cyber-physical systems(CPS)and digital twins(DTs)have gained extensive attention from researchers and practitioners in industry.With feedback loops in which physical processes affect cyber parts and vice versa,CPS and DTs can endow manufacturing systems with greater efficiency,resilience,and intelligence.CPS and DTs share the same essential concepts of an intensive cyber-physical connection,real-time interaction,organization integration,and in-depth collaboration.However,CPS and DTs are not identical from many perspectives,including their origin,development,engineering practices,cyber-physical mapping,and core elements.In order to highlight the differences and correlation between them,this paper reviews and analyzes CPS and DTs from multiple perspectives.
文摘This study was designed to evaluate the efficacy, tolerability, and sequential administration of abiraterone acetate （AA） and enzalutamide （Enz） for metastatic castration-resistant prostate cancer （mCRPC）. A literature search was performed with PubMed, Embase, and Web of Science databases to identify relevant studies. Reviewed literature included published phase III trials of AA or Enz in mCRPC and studies regarding their sequential administration. Given the difference in control arms in AA （active comparator） and Enz （true placebo） randomized phase III studies, indirect comparisons between AA and Enz in mCRPC showed no statistically significant difference in overall survival in prechemotherapy and postchemotherapy settings （HR. 0.90, 95% CI, 0.73-1.11; HR： 0.85, 95% CI, 0.68-1.07）. Compared with AA, Enz may better outperform control arms in treating mCRPC both before and after chemotherapy regarding secondary endpoints based on indirect comparisons： time to prostate-specific antigen （PSA） progression （HR. 0.34, 95% CI, 0.28-0.42; HR： 0.40, 95% CI, 0.30-0.53）, radiographic progression-free survival （HR： 0.37, 95% CI, 0.28-0.48; HR： 0.61, 95% CI, 0.50-0.74）, and PSA response rate （OR： 18.29, 95% CI, 11.20-29.88; OR： 10.69, 95% CI, 3.92-29.20）. With regard to the effectiveness of Enz following AA or AA following Enz, recent retrospective case series reported overall survival and secondary endpoints for patients with mCRPC progression after chemotherapy. However, confirmatory head-to-head trials are necessary to determine the optimal sequencing of these agents.
文摘In the future, solar energy will be a very important energy source. Several studies suppose that more than 45% of the energy in the world will be generated by photovoltaic array. Therefore it is necessary to concentrate our forces to reduce the application costs and to increment their performance. In order to reach the last aspect, it is important to note that the output characteristic of a photovoltaic array is nonlinear and changes with solar irradiation and cell’s temperature. Therefore a Maximum Power Point Tracking (MPPT) technique is needed to maximize the produced energy. This paper presents a comparative study of seven widely-adopted MPPT algorithms;their performance is evaluated using, for all the techniques, a common device with minimum hardware variations. In particular, this study compares the behaviors of each technique in presence of solar irradiation variations.
基金partially supported by National Natural Scientific Foundation of China[81620108026,81302393]
文摘Twelve healthy rats were divided into the T-2 toxin group receiving gavage of 1 mg/kg T-2 toxin and the control group receiving gavage of normal saline. Total relative concentrations of T-2 toxin and HT-2 toxin in the skeletal system（thighbone, knee joints, and costal cartilage） were significantly higher than those in the heart, liver, and kidneys（P 〈 0.05）. The relative concentrations of T-2 toxin and HT-2 toxin in the skeletal system（thighbone and costal cartilage） were also significantly higher than those in the heart, liver, and kidneys. The rats administered T-2 toxin showed rapid metabolism compared with that in rats administered HT-2 toxin, and the metabolic conversion rates in the different tissues were 68.20%-90.70%.
基金Supported by the Beijing Fund of Natural Science (Grant No. 6042025),China NKBRSF Project (Grant No. 2001CB409600) and the fund of Forest Protection Laboratory,State Forestry Administration
文摘The paper gives a brief description about the current main forest fire danger rating systems in the world, which in- clude forest fire danger rating system used in Canada, USA, Australia, and other countries. It shows the composition, structure and development of the main fire danger rating systems. The limitations of those systems are also discussed. Through a comparison of the three main forest fire danger rating systems the paper describes their differences on development, fuel complex descriptions, inputs and outputs, and their applications and finds that the technologies of the Canadian forest fire danger rating system can be adopted for China to develop a national forest fire danger rating system. Two steps are needed to develop our own national forest fire danger rating system. Firstly, we apply the CFFDRS directly. Then some studies should be done to calibrate the FDRS to local weather and fuel characteristics.
文摘BACKGROUND Gastritis is one of the most frequently diagnosed diseases requiring medical treatment in South Korea.Fexuprazan,a novel potassium-competitive acid blocker,has been approved for treating gastritis and erosive esophagitis.Meanwhile,rebamipide is the most commonly used mucoprotective agent for acute and chronic gastritis in real-world settings in South Korea.However,there have been no studies comparing the efficacy of these two drugs yet.AIM To compare the efficacy of fexuprazan with that of rebamipide for acute and chronic gastritis.METHODS This was a matching-adjusted indirect comparison.Individual patient data from a phase III study of fexuprazan(10 mg BID)were compared with cumulative data from two matching studies of rebamipide(100 mg TID).Erosion improvement and healing rates were compared between two weeks of fexurapan,two weeks of rebamipide,and four weeks of rebamipide.The two main outcome variables were presented as percentages,and the risk differences(RD)and 95%confidence intervals(CI)were calculated for the relative treatment effects.RESULTS In the primary analysis,the erosion improvement and healing rates after a twoweek treatment with fexuprazan were 64.5%and 53.2%,respectively,while a twoweek treatment with rebamipide resulted in erosion improvement and healing rates of 43.6%(RD:21.0%;95%CI:9.6-32.3;P<0.01)and 35.6%(RD:17.6%;95%CI:6.1-29.2;P=0.003),respectively.In the additional analysis,the erosion improvement and healing rates for the two-week fexuprazan treatment(64.2%and 51.2%,respectively)were similar to those obtained during a four-week treatment with rebamipide(60.6%;RD:3.6%;95%CI:-9.8,17.0;P=0.600 and 53.5%;RD:-2.3%;95%CI:-16.1,11.5;P=0.744,respectively).CONCLUSION The two-week fexuprazan treatment was superior to the two-week rebamipide treatment and similar to the fourweek rebamipide treatment for patients with gastritis.
文摘Food is the paramount necessity of the people,and safety is most essential for food. Food safety is related to people's fundamental interests,affecting people's basic health. It is an important factor in promoting people's livelihood development and social progress. Compared with European countries and the United States in developed food safety supervision systems,the development of food safety supervision system in China is still relatively backward. As food safety supervision is not in place,food safety incidents have occurred in recent years,so that public's panic about food safety has intensified. It has a strong impact on social stability and the food economy. Thus,strengthening the construction of food safety supervision system is imperative. Since experiencing a series of food safety incidents,the EU has gradually improved its food safety supervision system and has developed the most comprehensive and mature food safety supervision system in the world. On the basis of sorting out the characteristics of EU's food safety supervision system,the development direction of China's food safety supervision system is proposed from four aspects: supervisor,legal system,law enforcement ability and safety standards.
基金supported by the National Key Basic Research Program(2011CBA00200)the National Natural Science Foundation of China(61074050)
文摘The time optimal problem for a two level quantum sys-tem is studied. We compare two different control strategies of bang-bang control and the geometric control, respectively, es-pecial y in the case of minimizing the time of steering the state from North Pole to South Pole on the Bloch sphere with bounded control. The time performances are compared for different param-eters by the individual numerical simulation experiments, and the experimental results are analyzed. The results show that the ge-ometric control spends less time than the bang-bang control does.
基金Supported by the National Natural Science Foundation of China under Grant Nos 10990210 and 11475173the National Magnetic Confinement Fusion Energy Program of China under Grant Nos 2013GB106002 and 2014GB109002
文摘We compare three different methods to extract coherent modes from Doppler backscattering （DBS）, which are center of gravity （COG） of the complex amplitude spectrum, spectrum of DBS phase derivative （phase derivative method）, and phase spectrum, respectively. These three methods are all feasible to extract coherent modes, for example, geodesic acoustic mode oscillation. However, there are stilI differences between dealing with high frequency modes （several hundred kHz） and low frequency modes, （several kHz） hiding in DBS signal. There is a significant amount of power at low frequencies in the phase spectrum, which can be removed by using the phase derivative method and COG. High frequency modes are clearer by using the COO and the phase derivative method than the phase spectrum. The spectrum of DBS amplitude does not show the coherent modes detected by using COG, phase derivative method and phase spectrum. When two Doppler shifted peaks exist, coherent modes and their harmonics appear in the spectrum of DBS amplitude, which are introduced by the DBS phase.
