Image matching technology is theoretically significant and practically promising in the field of autonomous navigation.Addressing shortcomings of existing image matching navigation technologies,the concept of high-dim...Image matching technology is theoretically significant and practically promising in the field of autonomous navigation.Addressing shortcomings of existing image matching navigation technologies,the concept of high-dimensional combined feature is presented based on sequence image matching navigation.To balance between the distribution of high-dimensional combined features and the shortcomings of the only use of geometric relations,we propose a method based on Delaunay triangulation to improve the feature,and add the regional characteristics of the features together with their geometric characteristics.Finally,k-nearest neighbor(KNN)algorithm is adopted to optimize searching process.Simulation results show that the matching can be realized at the rotation angle of-8°to 8°and the scale factor of 0.9 to 1.1,and when the image size is 160 pixel×160 pixel,the matching time is less than 0.5 s.Therefore,the proposed algorithm can substantially reduce computational complexity,improve the matching speed,and exhibit robustness to the rotation and scale changes.展开更多
We propose and demonstrate a new approach for a high power pulse laser reflection sequence combination with a fast steering mirror(FSM). This approach possesses significant advantages for lasers combining with a varie...We propose and demonstrate a new approach for a high power pulse laser reflection sequence combination with a fast steering mirror(FSM). This approach possesses significant advantages for lasers combining with a variety of output power, wavelength, pulse duration, repetition rates and polarization. The maximum number of laser routes participating in combination principally depends on the FSM’s adjustment time of the step response, lasers’ repetition rates and pulse duration. A proof-of-principle experiment is performed with two 2-kW level pulsed beams. The results indicate that the combined beam has an excellent pointing stability with rms pointing jitter^8.5μrad. Meanwhile, a high combining efficiency of 98.6% is achieved with maintaining good beam quality.展开更多
Assembly sequence planning will be more difficult due to the increasingcomplexity of products.An integrated approach to assembly sequence planning of complex productsapplying de-composition-planning-combination strate...Assembly sequence planning will be more difficult due to the increasingcomplexity of products.An integrated approach to assembly sequence planning of complex productsapplying de-composition-planning-combination strategy is presented.First,an assembly is decomposedinto a hierarchical structure using an assembly structure representation based on connectors.Then,an assembly planning system is used to generate the sequences that are locally optimal for eachleaf partition hi the structure hierarchy.By combining the local sequences systematically in abottom-up manner and choosing suitable ones from the merged sequences,the assembly sequence of eachparent structure including the whole assembly is generated.An integrated system has beencompleted.A complex product is given to illustrate the feasibility and the practicality of theapproach.展开更多
Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM...Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely展开更多
The initial step in the resource utilization of Chinese medicine residues(CMRs)involves dehydration pretreatment,which results in high concentrations of organic wastewater and leads to environmental pollution.Meanwhil...The initial step in the resource utilization of Chinese medicine residues(CMRs)involves dehydration pretreatment,which results in high concentrations of organic wastewater and leads to environmental pollution.Meanwhile,to address the issue of anaerobic systems failing due to acidification under shock loading,a microaerobic expanded granular sludge bed(EGSB)and moving bed sequencing batch reactor(MBSBR)combined process was proposed in this study.Microaeration facilitated hydrolysis,improved the removal of nitrogen and phosphorus pollutants,maintained a low concentration of volatile fatty acids(VFAs),and enhanced system stability.In addition,microaeration promoted microbial richness and diversity,enriching three phyla:Bacteroidota,Synergistota and Firmicutes associated with hydrolytic acidification.Furthermore,aeration intensity in MBSBR was optimized.Elevated levels of dissolved oxygen(DO)impacted biofilm structure,suppressed denitrifying bacteria activity,led to nitrate accumulation,and hindered simultaneous nitrification and denitrification(SND).Maintaining a DO concentration of 2 mg/L enhanced the removal of nitrogen and phosphorus while conserving energy.The combined process achieved removal efficiencies of 98.25%,90.49%,and 98.55%for chemical oxygen demand(COD),total nitrogen(TN),and total phosphorus(TP),respectively.Typical pollutants liquiritin(LQ)and glycyrrhizic acid(GA)were completely degraded.This study presents an innovative approach for the treatment of high-concentration organic wastewater and provides a reliable solution for the pollution control in utilization of CMRs resources.展开更多
Schizophrenia is a common disorder with a high heritability, but its genetic architecture is still elusive.We implemented whole-genome sequencing(WGS) analysis of 8 families with monozygotic(MZ) twin pairs discordant ...Schizophrenia is a common disorder with a high heritability, but its genetic architecture is still elusive.We implemented whole-genome sequencing(WGS) analysis of 8 families with monozygotic(MZ) twin pairs discordant for schizophrenia to assess potential association of de novo mutations(DNMs) or inherited variants with susceptibility to schizophrenia. Eight non-synonymous DNMs(including one splicing site) were identified and shared by twins, which were either located in previously reported schizophrenia risk genes(p.V24689 I mutation in TTN, p.S2506 T mutation in GCN1L1, IVS3+1G > T in DOCK1) or had a benign to damaging effect according to in silico prediction analysis. By searching the inherited rare damaging or loss-of-function(LOF) variants and common susceptible alleles from three classes of schizophrenia candidate genes, we were able to distill genetic alterations in several schizophrenia risk genes, including GAD1, PLXNA2, RELN and FEZ1. Four inherited copy number variations(CNVs; including a large deletion at 16p13.11) implicated for schizophrenia were identified in four families, respectively. Most of families carried both missense DNMs and inherited risk variants, which might suggest that DNMs, inherited rare damaging variants and common risk alleles together conferred to schizophrenia susceptibility. Our results support that schizophrenia is caused by a combination of multiple genetic factors, with each DNM/variant showing a relatively small effect size.展开更多
Power grid construction projects are distinguished by their wide variety,high investment,long payback period,and close relation to national development and human welfare.To improve the investment accuracy in such proj...Power grid construction projects are distinguished by their wide variety,high investment,long payback period,and close relation to national development and human welfare.To improve the investment accuracy in such projects and effectively prevent investment risks,this paper proposes an investment optimization decision-making method for multiple power grid construction projects under a certain investment scale.Firstly,an in-depth analysis of the characteristics and development requirements of China’s power grid projects was performed.Thereafter,the time sequence and holographic method was adopted to conduct multi-dimensional,multi-perspective risk assessment of different parts of power grid projects,and a holographic risk assessment index system was developed.Moreover,an investment decision model considering the comprehensive risk based on combination weighting was developed according to the output and input of power grid construction projects.A new combination weighting optimization method that takes into account the investment willingness of enterprises was designed to improve the current weighting evaluation methods.Finally,the validity and applicability of the proposed evaluation method were verified by case examples.展开更多
In Chinese, Mathematics is “数学”, i.e. Numbers （数） Knowledge （学）. Human identifies us ourselves from the whole one of the Universe by means of numbers, and numbers are equal object status identities, and numb...In Chinese, Mathematics is “数学”, i.e. Numbers （数） Knowledge （学）. Human identifies us ourselves from the whole one of the Universe by means of numbers, and numbers are equal object status identities, and numbers counting means repetition, i.e. the process or time dimension. Given a series of n numbers, a1 , a2 , … , an , n∈N, i.e. the n objects of status, and a general formula a（i） for ordering all of the number terms by i （i=1 to n） can be generated, which shows a process of counting, and from sequencing to progression, some properties are extracted.展开更多
The theory of shared control combines organically the control of every controlled ele-ments and with it all the controlled elements share the same control element. Applying theschemes of shared control searched by ass...The theory of shared control combines organically the control of every controlled ele-ments and with it all the controlled elements share the same control element. Applying theschemes of shared control searched by assembly programs, an integrated control of all the ele-ments is fulfilled. The distinguishing point of the method is that the maximum control output canbe obtained with the least input information. Hence it is the optimum for the conversion of com-bination states. Finally, a thared rotary valve is designed, and it is the simplest with only onegroup of control holes.展开更多
in this paper,the statistical prOPerties of random combination sequences are discussed.Thevalue of E{R(r)}and the upper bound of E{A(r)}are derived.In the end,a new method to find a longsequence with low autocorrelati...in this paper,the statistical prOPerties of random combination sequences are discussed.Thevalue of E{R(r)}and the upper bound of E{A(r)}are derived.In the end,a new method to find a longsequence with low autocorrelation value is given.展开更多
基金supported by the National Natural Science Foundations of China(Nos.51205193,51475221)
文摘Image matching technology is theoretically significant and practically promising in the field of autonomous navigation.Addressing shortcomings of existing image matching navigation technologies,the concept of high-dimensional combined feature is presented based on sequence image matching navigation.To balance between the distribution of high-dimensional combined features and the shortcomings of the only use of geometric relations,we propose a method based on Delaunay triangulation to improve the feature,and add the regional characteristics of the features together with their geometric characteristics.Finally,k-nearest neighbor(KNN)algorithm is adopted to optimize searching process.Simulation results show that the matching can be realized at the rotation angle of-8°to 8°and the scale factor of 0.9 to 1.1,and when the image size is 160 pixel×160 pixel,the matching time is less than 0.5 s.Therefore,the proposed algorithm can substantially reduce computational complexity,improve the matching speed,and exhibit robustness to the rotation and scale changes.
基金Supported by the Knowledge Innovation Program of Chinese Academy of Sciences under Gant No GJJSTD20180004
文摘We propose and demonstrate a new approach for a high power pulse laser reflection sequence combination with a fast steering mirror(FSM). This approach possesses significant advantages for lasers combining with a variety of output power, wavelength, pulse duration, repetition rates and polarization. The maximum number of laser routes participating in combination principally depends on the FSM’s adjustment time of the step response, lasers’ repetition rates and pulse duration. A proof-of-principle experiment is performed with two 2-kW level pulsed beams. The results indicate that the combined beam has an excellent pointing stability with rms pointing jitter^8.5μrad. Meanwhile, a high combining efficiency of 98.6% is achieved with maintaining good beam quality.
基金supported by National Natural Science Foundation of China(No.59990470-2).
文摘Assembly sequence planning will be more difficult due to the increasingcomplexity of products.An integrated approach to assembly sequence planning of complex productsapplying de-composition-planning-combination strategy is presented.First,an assembly is decomposedinto a hierarchical structure using an assembly structure representation based on connectors.Then,an assembly planning system is used to generate the sequences that are locally optimal for eachleaf partition hi the structure hierarchy.By combining the local sequences systematically in abottom-up manner and choosing suitable ones from the merged sequences,the assembly sequence of eachparent structure including the whole assembly is generated.An integrated system has beencompleted.A complex product is given to illustrate the feasibility and the practicality of theapproach.
基金the funds of "the Youth Fund of Nantong Health Bureau 2015",ID:WQ2015009
文摘Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely
基金funding from the National Key R&D Program of China(No.2019YFC1906600)the National Natural Science Foundation of China(No.52200049)+3 种基金the China Postdoctoral Science Foundation(No.2022TQ0089)the Heilongjiang Province Postdoctoral Science Foundation(No.LBH-Z22181)the State Key Laboratory of Urban Water Resource and Environment(Harbin Institute of Technology)(No.2023DX06)the Fundamental Research Funds for the Central Universities。
文摘The initial step in the resource utilization of Chinese medicine residues(CMRs)involves dehydration pretreatment,which results in high concentrations of organic wastewater and leads to environmental pollution.Meanwhile,to address the issue of anaerobic systems failing due to acidification under shock loading,a microaerobic expanded granular sludge bed(EGSB)and moving bed sequencing batch reactor(MBSBR)combined process was proposed in this study.Microaeration facilitated hydrolysis,improved the removal of nitrogen and phosphorus pollutants,maintained a low concentration of volatile fatty acids(VFAs),and enhanced system stability.In addition,microaeration promoted microbial richness and diversity,enriching three phyla:Bacteroidota,Synergistota and Firmicutes associated with hydrolytic acidification.Furthermore,aeration intensity in MBSBR was optimized.Elevated levels of dissolved oxygen(DO)impacted biofilm structure,suppressed denitrifying bacteria activity,led to nitrate accumulation,and hindered simultaneous nitrification and denitrification(SND).Maintaining a DO concentration of 2 mg/L enhanced the removal of nitrogen and phosphorus while conserving energy.The combined process achieved removal efficiencies of 98.25%,90.49%,and 98.55%for chemical oxygen demand(COD),total nitrogen(TN),and total phosphorus(TP),respectively.Typical pollutants liquiritin(LQ)and glycyrrhizic acid(GA)were completely degraded.This study presents an innovative approach for the treatment of high-concentration organic wastewater and provides a reliable solution for the pollution control in utilization of CMRs resources.
基金supported by the Strategic Priority Research Program (B) of the Chinese Academy of Sciences (XDB02020003 and XDB02030002)the Bureau of Frontier Sciences and Education,Chinese Academy of Sciences (QYZDJ-SSW-SMC005)+3 种基金the National Natural Science Foundation of China (Nos. 81088001,81271484,81471361 and 81371480)the Beijing Training Project for the Leading Talents in S & T (Z151100000315020)the National Key Basic Research and Development Program (973) (2012CB517904)the CAS/SAFEA International Partnership Programme for Creative Research Teams (Y2CX131003)
文摘Schizophrenia is a common disorder with a high heritability, but its genetic architecture is still elusive.We implemented whole-genome sequencing(WGS) analysis of 8 families with monozygotic(MZ) twin pairs discordant for schizophrenia to assess potential association of de novo mutations(DNMs) or inherited variants with susceptibility to schizophrenia. Eight non-synonymous DNMs(including one splicing site) were identified and shared by twins, which were either located in previously reported schizophrenia risk genes(p.V24689 I mutation in TTN, p.S2506 T mutation in GCN1L1, IVS3+1G > T in DOCK1) or had a benign to damaging effect according to in silico prediction analysis. By searching the inherited rare damaging or loss-of-function(LOF) variants and common susceptible alleles from three classes of schizophrenia candidate genes, we were able to distill genetic alterations in several schizophrenia risk genes, including GAD1, PLXNA2, RELN and FEZ1. Four inherited copy number variations(CNVs; including a large deletion at 16p13.11) implicated for schizophrenia were identified in four families, respectively. Most of families carried both missense DNMs and inherited risk variants, which might suggest that DNMs, inherited rare damaging variants and common risk alleles together conferred to schizophrenia susceptibility. Our results support that schizophrenia is caused by a combination of multiple genetic factors, with each DNM/variant showing a relatively small effect size.
基金supported by the State Grid Science and Technology Project (SGTYHT/16-JS-198)
文摘Power grid construction projects are distinguished by their wide variety,high investment,long payback period,and close relation to national development and human welfare.To improve the investment accuracy in such projects and effectively prevent investment risks,this paper proposes an investment optimization decision-making method for multiple power grid construction projects under a certain investment scale.Firstly,an in-depth analysis of the characteristics and development requirements of China’s power grid projects was performed.Thereafter,the time sequence and holographic method was adopted to conduct multi-dimensional,multi-perspective risk assessment of different parts of power grid projects,and a holographic risk assessment index system was developed.Moreover,an investment decision model considering the comprehensive risk based on combination weighting was developed according to the output and input of power grid construction projects.A new combination weighting optimization method that takes into account the investment willingness of enterprises was designed to improve the current weighting evaluation methods.Finally,the validity and applicability of the proposed evaluation method were verified by case examples.
文摘In Chinese, Mathematics is “数学”, i.e. Numbers （数） Knowledge （学）. Human identifies us ourselves from the whole one of the Universe by means of numbers, and numbers are equal object status identities, and numbers counting means repetition, i.e. the process or time dimension. Given a series of n numbers, a1 , a2 , … , an , n∈N, i.e. the n objects of status, and a general formula a（i） for ordering all of the number terms by i （i=1 to n） can be generated, which shows a process of counting, and from sequencing to progression, some properties are extracted.
文摘The theory of shared control combines organically the control of every controlled ele-ments and with it all the controlled elements share the same control element. Applying theschemes of shared control searched by assembly programs, an integrated control of all the ele-ments is fulfilled. The distinguishing point of the method is that the maximum control output canbe obtained with the least input information. Hence it is the optimum for the conversion of com-bination states. Finally, a thared rotary valve is designed, and it is the simplest with only onegroup of control holes.
文摘in this paper,the statistical prOPerties of random combination sequences are discussed.Thevalue of E{R(r)}and the upper bound of E{A(r)}are derived.In the end,a new method to find a longsequence with low autocorrelation value is given.
