With the development of large-scale spectral surveys, fiber positioning technology has been developing rapidly. Because of the performance advantages of a four-quadrant(4Q) detector, a fiber positioning and real-tim...With the development of large-scale spectral surveys, fiber positioning technology has been developing rapidly. Because of the performance advantages of a four-quadrant(4Q) detector, a fiber positioning and real-time monitoring system based on the 4Q detector is proposed. The detection accuracy of this system is directly determined by the precision of the center of the spot. A Gaussian fitting algorithm based on the 4Q detector is studied and applied in the fiber positioning process to improve the calculated accuracy of the spot center. The relationship between the center position of the incident spot and the detector output signal is deduced. An experimental platform is built to complete the simulated experiment. Then we use the Gaussian fitting method to process experimental data, compare the fitting value with the theoretical one and calculate the corresponding error.展开更多
The spatial resolution of a commercial two-dimensional(2D)ionization chamber(IC)array is limited by the size of the individual detector and the center-to-center distance between sensors.For dose distributions with are...The spatial resolution of a commercial two-dimensional(2D)ionization chamber(IC)array is limited by the size of the individual detector and the center-to-center distance between sensors.For dose distributions with areas of steep dose gradients,inter-detector dose values are derived by the interpolation of nearby detector readings in the conventional mathematical interpolation of 2D IC array measurements.This may introduce significant errors,particularly in proton spot scanning radiotherapy.In this study,by combining logfile-based reconstructed dose values and detector measurements with the Laplacian pyramid image blending method,a novel method is proposed to obtain a reformatted dose distribution that provides an improved estimation of the delivered dose distribution with high spatial resolution.Meanwhile,the similarity between the measured original data and the downsampled logfilebased reconstructed dose is regarded as the confidence of the reformatted dose distribution.Furthermore,we quantify the performance benefits of this new approach by directly comparing the reformatted dose distributions with 2D IC array detector mathematically interpolated measurements and original low-resolution measurements.The result shows that this new method is better than the mathematical interpolation and achieves gamma pass rates similar to those of the original low-resolution measurements.The reformatted dose distributions generally yield a confidence exceeding 95%.展开更多
Cylindrical coplanar-grid configurations,which offer a lot of advantages over established designs,can effectively overcome the problem of poor hole collection.Finite element analysis is utilized for simulating the pot...Cylindrical coplanar-grid configurations,which offer a lot of advantages over established designs,can effectively overcome the problem of poor hole collection.Finite element analysis is utilized for simulating the potential distribution of the cylindrical coplanar-grid detector under different models by varying the widths of grid and pitch of electrodes. In addition, a modified grid pattern has been discussed to improve the weighting potential match between two grids. In this way, the geometry of electrodes for cylindrical coplanar-grid detectors is optimized.展开更多
We report a resonant method to measure the wall capacitance(C_w) and solution resistance(R_S) in a capacitively coupled contactless conductivity detector(C^4D).Under the typical operating conditions in capillary...We report a resonant method to measure the wall capacitance(C_w) and solution resistance(R_S) in a capacitively coupled contactless conductivity detector(C^4D).Under the typical operating conditions in capillary electrophoresis(I.D.50μm,O.D. 360μm,electrode length of 4 mm,electrode gap of 1 mm,frequency of 200 kHz),the values of C_w measured in 1 and 20 mmol/L NaCl solutions are 2.8 and 32 fF,which are only 1.1%and 12%of prediction by the equation in references,respectively.The value of R_S is less than the prediction in solutions withκ〈0.02 S/m.The response current of C^4D is due to the change in C_w because the total impedance of a C^4D is composed mainly by the impedance from C_w.展开更多
In X-ray absorption fine structure(XAFS) experiments,Soller slits are widely used as filter devices in order to improve the signal to noise ratio.Performing high accuracy manual focusing operations is a time-consuming...In X-ray absorption fine structure(XAFS) experiments,Soller slits are widely used as filter devices in order to improve the signal to noise ratio.Performing high accuracy manual focusing operations is a time-consuming process;therefore,this work introduces an automatic focusing method for Soller slits in multi-element fluorescence detectors.This method establishes a relation model between the fluorescence intensity distribution and the coordinates of the fluorescence excitation point.According to this relation model,the actual coordinates of the fluorescence excitation point can be deduced from the detected fluorescence intensity distribution and used in focusing operations.This method has proven to be feasible in an XAFS experiment at the BL14W1 beamline of the Shanghai Synchrotron Radiation Facility.展开更多
Microcapsules containing the aqueous solution of Azur B of a water soluble dye were prepared with the melting dispersion cooling method and applied to the amplification detector of plant DNA. Paraffin wax with melting...Microcapsules containing the aqueous solution of Azur B of a water soluble dye were prepared with the melting dispersion cooling method and applied to the amplification detector of plant DNA. Paraffin wax with melting temperature of 75°C was used as the shell material. In the experiment, the aqueous solution (W) of Azur B as the core material was dispersed in the melted paraffin wax (O) to form the (W/O) emulsion and then, the (W/O) emulsion was dispersed in the silicon oil (O’) as the continuous phase to form the (W/O)/O’ emulsion at 85°C. After formation of the (W/O)/O’ emulsion, the microcapsules were prepared by cooling the (W/O)/O’ emulsion to 50°C. The microcapsules were prepared by changing the concentration of oil soluble surfactant in the (W/O) emulsion and the volume of the (W/O) emulsion in the (W/O)/O’ emulsion. The microencapsulation efficiency increased with the concentration of oil soluble surfactant and finally became 100% under the optimum conditions. Furthermore, the microcapsules were melted down at temperature of 85°C to reveal the sharp thermal responsibility and to release the aqueous solution of Azur B. As a result, it was found that the microcapsules were able to be applied to the amplification detector of plant DNA by utilizing the reaction between DNA and Azur B.展开更多
Purpose: To present an application of the anisotropic diffusion (AD) method to improve the accuracy of the functional images of perfusion parameters such as cerebral blood flow (CBF), cerebral blood volume (CBV) and m...Purpose: To present an application of the anisotropic diffusion (AD) method to improve the accuracy of the functional images of perfusion parameters such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) generated from cerebral CT perfusion studies using multi-detector row CT (MDCT). Materials and Methods: Continuous scans (1 sec/rotation ×60 sec) consisting of four 5-mm-thick contiguous slices were acquired after an intravenous injection of iodinated contrast material in 6 patients with cerebrovascular disease using an MDCT scanner with a tube voltage of 80 kVp and a tube current of 200 mA. New image data were generated by thinning out the above original images at an interval of 2 sec or 3 sec. The thinned-out images were then interpolated by linear interpolation to generate the same number of images as originally acquired. The CBF, CBV and MTT images were generated using deconvolution analysis based on singular value decomposition. Results: When using the AD method, the correlation coefficient between the MTT values obtained from the original and thinned-out images was significantly improved. Furthermore, the coefficients of variation of the CBF, CBV and MTT values in the white matter significantly decreased as compared to not using the AD method. Conclusion: Our results suggest that the AD method is useful for improving the accuracy of the functional images of perfusion parameters and for reducing radiation exposure in cerebral CT perfusion studies using MDCT.展开更多
Cadmium telluride(CdTe),which has a high average atomic number and a unique band structure,is a leading material for room-temperature X/γ-ray detectors.Resistivity and mobility are the two most important properties o...Cadmium telluride(CdTe),which has a high average atomic number and a unique band structure,is a leading material for room-temperature X/γ-ray detectors.Resistivity and mobility are the two most important properties of detector-grade CdTe single crystals.However,despite decades of research,the fabrication of high-resistivity and high-mobility CdTe single crystals faces persistent challenges,primarily because the stoichiometric composition cannot be well controlled owing to the high volatility of Cd under high-temperature conditions.This volatility introduces Te inclusions and cadmium vacancies(V_(Cd))into the as-grown CdTe ingot,which significantly degrades the device performance.In this study,we successfully obtained detector-grade CdTe single crystals by simultaneously employing a Cd reservoir and chlorine(Cl)dopants via a vertical gradient freeze(VGF)method.By installing a Cd reservoir,we can maintain the Cd pressure under the crystal growth conditions,thereby preventing the accumulation of Te in the CdTe ingot.Additionally,the existence of the Cl dopant helps improve the CdTe resistivity by minimizing V_(Cd)density through the formation of an acceptor complex(Cl_(Te)-V_(Cd))^(-1).The crystalline quality of the obtained CdTe(Cl)was evidenced by a reduction in large Te inclusions,high optical transmission(60%),and a sharp absorption edge(1.456 eV).The presence of substitutional Cl dopants,known as Cl_(Te)^(+),simultaneously supports the record high resistivity of 1.5×10^(10)Ω·cm and remarkable electron mobility of 1075±88 cm^(2)V^(-1)s^(-1)simultaneously,has been confirmed by photoluminescence spectroscopy.Moreover,using our crystals,we fabricated a planar detector withμτ_(e)of(1.11±0.04)×10^(-4)cm^(2)∕V,which performed with a decent radiation-detection feature.This study demonstrates that the vapor-pressure-controlled VGF method is a viable technical route for fabricating detector-grade CdTe crystals.展开更多
A time-of-flight Highly Granular Neutron Detector(HGND)with a multilayer longitudinal structure of interleaved absorber and scintillator plates,high transverse granularity,and time resolution of approximately 150 ps i...A time-of-flight Highly Granular Neutron Detector(HGND)with a multilayer longitudinal structure of interleaved absorber and scintillator plates,high transverse granularity,and time resolution of approximately 150 ps is currently under development.The detector is designed to identify neutrons produced in nucleus-nucleus collisions and measure neutron kinetic energies of 0.3-4 GeV by the time-of-flight method in the BM@N experiment at the NICA accelerator complex at JINR.To validate the concept of full-scale HGND,a compact HGND prototype was first designed and built,and its performance was studied in the BM@N experiment.The acceptance of the HGND prototype and the detection efficiency of forward neutrons emitted in hadronic fragmentation and electromagnetic dissociation(EMD)of 3.8A GeV124Xe projectiles interacting with a CsI target were calculated by means of the DCM-QGSM-SMM and RELDIS models,respectively.The energy distributions of the forward spectator neutrons and neutrons from the EMD were measured and compared with the simulations.The developed methods will be used to calibrate the full-scale HGND and study its efficiency.展开更多
In high-resolution cone-beam computed tomography (CBCT) using the flat-panel detector, imperfect or defect detector elements cause ring artifacts due to the none-uniformity of their X-ray response. They often distur...In high-resolution cone-beam computed tomography (CBCT) using the flat-panel detector, imperfect or defect detector elements cause ring artifacts due to the none-uniformity of their X-ray response. They often disturb the image quality. A dedicated fitting correction method for high-resolution micro-CT is presented. The method converts each elementary X-ray response curve to an average one, and eliminates response inconsistency among pixels. Other factors of the method are discussed, such as the correction factor variability by different sampling frames and nonlinear factors over the whole spectrum. Results show that the noise and artifacts are both reduced in reconstructed images展开更多
An accurate energy calibration of a 5"× 2" BC501A liquid scintillator-based neutron detector by means of photon sources and the unfolding of pulse height spectra are described. The photon responses were measure...An accurate energy calibration of a 5"× 2" BC501A liquid scintillator-based neutron detector by means of photon sources and the unfolding of pulse height spectra are described. The photon responses were measured with 22Na, 137Cs and 54Mn photon sources and simulated using the GRESP code, which was developed at the Physiknlisch Technische Bundesanstalt in Germany. Pulse height spectra produced by three different photon sources were employed to investigate the effects of the unfolding techniques. It was found that the four unfolding codes of the HEPRO and UMG3.3 packages, including GRAVEL, UNFANA, MIEKE and MAXED, performed well with the test spectra and produced generally consistent results. They could therefore be used to obtain neutron energy spectra in toknmak experiments.展开更多
The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral ...The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral analysis method is proposed in this study.In this method,overlapping peaks are located using a continuous wavelet transform.An improved quadratic convolution method is proposed to calculate the widths of the peaks and establish a fourth-order filter model to estimate the Compton edge baseline with the overlapping peaks.Combined with the adaptive sensitive nonlinear iterative peak,this method can effectively subtracts the background.Finally,a function describing the peak shape as a filter is used to deconvolve the energy spectrum to achieve accurate qualitative and quantitative analyses of the nuclide without the aid of a nuclide library.Gamma spectrum acquisition experiments for standard point sources of Cs-137 and Eu-152,a segmented gamma scanning experiment for a 200 L standard drum,and a Monte Carlo simulation experiment for triple overlapping peaks using the closest energy of three typical LILW nuclides(Sb-125,Sb-124,and Cs-134)are conducted.The results of the experiments indicate that(1)the novel method and gamma vision(GV)with an accurate nuclide library have the same spectral analysis capability,and the peak area calculation error is less than 4%;(2)compared with the GV,the analysis results of the novel method are more stable;(3)the novel method can be applied to the activity measurement of LILW,and the error of the activity reconstruction at the equivalent radius is 2.4%;and(4)The proposed novel method can quantitatively analyze all nuclides in LILW without a nuclide library.This novel method can improve the accuracy and precision of LILW measurements,provide key technical support for the reasonable disposal of LILW,and ensure the safety of humans and the environment.展开更多
As the areas of CCD detectors and CCD mosaics have become larger and larger,the number of readout channels in astronomical cameras has increased accordingly to keep the image readout time within an acceptable range.Fo...As the areas of CCD detectors and CCD mosaics have become larger and larger,the number of readout channels in astronomical cameras has increased accordingly to keep the image readout time within an acceptable range.For the large area cameras or the mosaic cameras,the analog Correlated Double Sampling(aCDS)circuit used in traditional astronomical cameras for suppressing readout noise is difficult to integrate into the camera controllers within the constraints of the space and energy consumption.Recently,digital CDS(dCDS)technology has been developed to solve this problem,which also offers novel analysis and noise suppression methods.In this study,a mathematical model is presented to conveniently analyze the frequency characteristic of a dCDS circuit,which is then simulated by a numerical method for investigating the noise suppression capability with different sampling weights.Importantly,using this model,the extreme point with lowest readout noise can be predicted for a certain dCDS model;and for a specific CCD readout frequency,readout noise can be suppressed by selecting the proper dCDS model.A testing system is then constructed for validating the efficiency of the proposed method.展开更多
A particle detector array designed for light-charged particles, known as the CsI-bowl, was built for exit channel selection for in-beam γ-ray spectroscopy experiments. This device is composed of 64 CsI(Tl) detectors,...A particle detector array designed for light-charged particles, known as the CsI-bowl, was built for exit channel selection for in-beam γ-ray spectroscopy experiments. This device is composed of 64 CsI(Tl) detectors, organized in a structure reminiscent of a tea-bowl. High quantum efficiency photodiodes, characterized by their minimal mass, were employed to collect scintillation light. Its design, construction, particle identification resolution, and its effectiveness in relation to exit channel selection are described in this paper. In source tests, the optimal figure of merit for the identification of α-particles and γ-rays using the charge comparison method was found to be 3.3 and 12.1 for CsI detectors coupled to photodiodes and avalanche photodiodes, respectively. The CsI-bowl demonstrated effectiveness in identifying particles, specifically the emission of protons and α-particles in the58Ni(19F, xpyn) fusion–evaporation reaction, thereby enabling the selection of the desired exit channels.展开更多
This paper focuses on the relic gravity waves produced during the transition from a radiation-dominated inflationary phase to a dust-dominated Friedman-Robertson-Walker-type expansion. We discuss how to investigate th...This paper focuses on the relic gravity waves produced during the transition from a radiation-dominated inflationary phase to a dust-dominated Friedman-Robertson-Walker-type expansion. We discuss how to investigate the spectral energy density by the latest space-based CWs detectors at f =0.1 Hz (i.e. DECICO). In the case of power-law and exponential inflation, we apply the cross-correlation method to the latest detector and get the time dependence of the very early Hubble pararneter.展开更多
The Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)mission is designed to monitor the Gamma-Ray Bursts(GRBs)associated with gravitational waves and other high-energy transient sources...The Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)mission is designed to monitor the Gamma-Ray Bursts(GRBs)associated with gravitational waves and other high-energy transient sources.The mission consists of two microsatellites which are planned to operate at the opposite sides of the Earth.Each GECAM satellite could detect and localize GRBs in about 8 keV-5 MeV with its 25 Gamma-Ray Detectors(GRDs).In this work,we report the in-flight energy calibration of GRDs using the characteristic gamma-ray lines in the background spectra,and show their performance evolution during the commissioning phase.Besides,a preliminary cross-calibration of energy response with Fermi GBM data is also presented,validating the energy response of GRDs.展开更多
A high-performance liquid chromatography analysis method with an evaporative light-scattering detector has been developed for the separation and quantitative analysis of free fatty acids in biological matrices. Core-s...A high-performance liquid chromatography analysis method with an evaporative light-scattering detector has been developed for the separation and quantitative analysis of free fatty acids in biological matrices. Core-shell reversed-phase high-performance liquid chromatography separation of 10 free fatty acids is achieved within 10.5 min using a methanol/water (0.05% trifluoroacetic acid) eluent gradient. After optimization, the drift tube and nebulization temperature of the evaporative light-scattering detector was set at 35°C, nitrogen flow-rate at 1.1 standard liter per minute and column temperature at 25°C. All calibration curves showed good regression (r2 > 0.9975). A validation procedure following the International Conference on Harmonisation guidelines was implemented to certify the method. Relative standard deviations did not exceed 1.5% and 4.25% for repeatability and reproducibility respectively.展开更多
An electronic personal dosimeter mainly uses a Si-PIN photodiode as X-and gamma-ray detectors.The photon energy response of this instrument is inconsistent in the case of no correction,which seriously affects the accu...An electronic personal dosimeter mainly uses a Si-PIN photodiode as X-and gamma-ray detectors.The photon energy response of this instrument is inconsistent in the case of no correction,which seriously affects the accurate monitoring of personal dose equivalent H_p(10)parameters for radiation workers.For this reason,in this paper we propose a method of combining composite screen detection technology,multichannel measurement technology,and the channel ratio method to achieve accurate measurement of the personal dose equivalent parameters.According to China National Standard GB/T 13161-2003 and National Verification Regulation JJG 1009-2006,the instrument was tested in the energy range between 48 keV and 1.25 MeV.The experimental results showed that the difference of energy response to ^(137)C_S corrected by the new method was almost constant within ±6.0%,which fulfilled the ±30% requirement of GB/T 13161-2003 and JJG1009-2006.Meanwhile,the method proposed obtained energy information regarding the radiation field.展开更多
基金support by the Fundamental Research Funds for the Central Universities of China (2013/B15020271)the National Natural Science Foundation of China (1014/515029111)the National Undergraduate Training Program for Innovation and Entrepreneurship (201610294069)
文摘With the development of large-scale spectral surveys, fiber positioning technology has been developing rapidly. Because of the performance advantages of a four-quadrant(4Q) detector, a fiber positioning and real-time monitoring system based on the 4Q detector is proposed. The detection accuracy of this system is directly determined by the precision of the center of the spot. A Gaussian fitting algorithm based on the 4Q detector is studied and applied in the fiber positioning process to improve the calculated accuracy of the spot center. The relationship between the center position of the incident spot and the detector output signal is deduced. An experimental platform is built to complete the simulated experiment. Then we use the Gaussian fitting method to process experimental data, compare the fitting value with the theoretical one and calculate the corresponding error.
文摘The spatial resolution of a commercial two-dimensional(2D)ionization chamber(IC)array is limited by the size of the individual detector and the center-to-center distance between sensors.For dose distributions with areas of steep dose gradients,inter-detector dose values are derived by the interpolation of nearby detector readings in the conventional mathematical interpolation of 2D IC array measurements.This may introduce significant errors,particularly in proton spot scanning radiotherapy.In this study,by combining logfile-based reconstructed dose values and detector measurements with the Laplacian pyramid image blending method,a novel method is proposed to obtain a reformatted dose distribution that provides an improved estimation of the delivered dose distribution with high spatial resolution.Meanwhile,the similarity between the measured original data and the downsampled logfilebased reconstructed dose is regarded as the confidence of the reformatted dose distribution.Furthermore,we quantify the performance benefits of this new approach by directly comparing the reformatted dose distributions with 2D IC array detector mathematically interpolated measurements and original low-resolution measurements.The result shows that this new method is better than the mathematical interpolation and achieves gamma pass rates similar to those of the original low-resolution measurements.The reformatted dose distributions generally yield a confidence exceeding 95%.
文摘Cylindrical coplanar-grid configurations,which offer a lot of advantages over established designs,can effectively overcome the problem of poor hole collection.Finite element analysis is utilized for simulating the potential distribution of the cylindrical coplanar-grid detector under different models by varying the widths of grid and pitch of electrodes. In addition, a modified grid pattern has been discussed to improve the weighting potential match between two grids. In this way, the geometry of electrodes for cylindrical coplanar-grid detectors is optimized.
基金supported by the National Natural Science Foundation of China(nos.20975062 and 21175084)
文摘We report a resonant method to measure the wall capacitance(C_w) and solution resistance(R_S) in a capacitively coupled contactless conductivity detector(C^4D).Under the typical operating conditions in capillary electrophoresis(I.D.50μm,O.D. 360μm,electrode length of 4 mm,electrode gap of 1 mm,frequency of 200 kHz),the values of C_w measured in 1 and 20 mmol/L NaCl solutions are 2.8 and 32 fF,which are only 1.1%and 12%of prediction by the equation in references,respectively.The value of R_S is less than the prediction in solutions withκ〈0.02 S/m.The response current of C^4D is due to the change in C_w because the total impedance of a C^4D is composed mainly by the impedance from C_w.
基金supported by National Nature Science Foundation of China(No.11175244)
文摘In X-ray absorption fine structure(XAFS) experiments,Soller slits are widely used as filter devices in order to improve the signal to noise ratio.Performing high accuracy manual focusing operations is a time-consuming process;therefore,this work introduces an automatic focusing method for Soller slits in multi-element fluorescence detectors.This method establishes a relation model between the fluorescence intensity distribution and the coordinates of the fluorescence excitation point.According to this relation model,the actual coordinates of the fluorescence excitation point can be deduced from the detected fluorescence intensity distribution and used in focusing operations.This method has proven to be feasible in an XAFS experiment at the BL14W1 beamline of the Shanghai Synchrotron Radiation Facility.
文摘Microcapsules containing the aqueous solution of Azur B of a water soluble dye were prepared with the melting dispersion cooling method and applied to the amplification detector of plant DNA. Paraffin wax with melting temperature of 75°C was used as the shell material. In the experiment, the aqueous solution (W) of Azur B as the core material was dispersed in the melted paraffin wax (O) to form the (W/O) emulsion and then, the (W/O) emulsion was dispersed in the silicon oil (O’) as the continuous phase to form the (W/O)/O’ emulsion at 85°C. After formation of the (W/O)/O’ emulsion, the microcapsules were prepared by cooling the (W/O)/O’ emulsion to 50°C. The microcapsules were prepared by changing the concentration of oil soluble surfactant in the (W/O) emulsion and the volume of the (W/O) emulsion in the (W/O)/O’ emulsion. The microencapsulation efficiency increased with the concentration of oil soluble surfactant and finally became 100% under the optimum conditions. Furthermore, the microcapsules were melted down at temperature of 85°C to reveal the sharp thermal responsibility and to release the aqueous solution of Azur B. As a result, it was found that the microcapsules were able to be applied to the amplification detector of plant DNA by utilizing the reaction between DNA and Azur B.
文摘Purpose: To present an application of the anisotropic diffusion (AD) method to improve the accuracy of the functional images of perfusion parameters such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) generated from cerebral CT perfusion studies using multi-detector row CT (MDCT). Materials and Methods: Continuous scans (1 sec/rotation ×60 sec) consisting of four 5-mm-thick contiguous slices were acquired after an intravenous injection of iodinated contrast material in 6 patients with cerebrovascular disease using an MDCT scanner with a tube voltage of 80 kVp and a tube current of 200 mA. New image data were generated by thinning out the above original images at an interval of 2 sec or 3 sec. The thinned-out images were then interpolated by linear interpolation to generate the same number of images as originally acquired. The CBF, CBV and MTT images were generated using deconvolution analysis based on singular value decomposition. Results: When using the AD method, the correlation coefficient between the MTT values obtained from the original and thinned-out images was significantly improved. Furthermore, the coefficients of variation of the CBF, CBV and MTT values in the white matter significantly decreased as compared to not using the AD method. Conclusion: Our results suggest that the AD method is useful for improving the accuracy of the functional images of perfusion parameters and for reducing radiation exposure in cerebral CT perfusion studies using MDCT.
基金supported by the National Key R&D Program(Nos.2023YFE0108500 and 2023YFF0719500)the National Natural Science Foundation of China(Nos.52072300 and 52302199)+2 种基金the Guangdong Basic and Applied Basic Research Foundation(No.2022A1515110538)Key Research and Development Program of Shaanxi(No.2023-GHZD-48)the Fundamental Research Funds for the Central Universities.
文摘Cadmium telluride(CdTe),which has a high average atomic number and a unique band structure,is a leading material for room-temperature X/γ-ray detectors.Resistivity and mobility are the two most important properties of detector-grade CdTe single crystals.However,despite decades of research,the fabrication of high-resistivity and high-mobility CdTe single crystals faces persistent challenges,primarily because the stoichiometric composition cannot be well controlled owing to the high volatility of Cd under high-temperature conditions.This volatility introduces Te inclusions and cadmium vacancies(V_(Cd))into the as-grown CdTe ingot,which significantly degrades the device performance.In this study,we successfully obtained detector-grade CdTe single crystals by simultaneously employing a Cd reservoir and chlorine(Cl)dopants via a vertical gradient freeze(VGF)method.By installing a Cd reservoir,we can maintain the Cd pressure under the crystal growth conditions,thereby preventing the accumulation of Te in the CdTe ingot.Additionally,the existence of the Cl dopant helps improve the CdTe resistivity by minimizing V_(Cd)density through the formation of an acceptor complex(Cl_(Te)-V_(Cd))^(-1).The crystalline quality of the obtained CdTe(Cl)was evidenced by a reduction in large Te inclusions,high optical transmission(60%),and a sharp absorption edge(1.456 eV).The presence of substitutional Cl dopants,known as Cl_(Te)^(+),simultaneously supports the record high resistivity of 1.5×10^(10)Ω·cm and remarkable electron mobility of 1075±88 cm^(2)V^(-1)s^(-1)simultaneously,has been confirmed by photoluminescence spectroscopy.Moreover,using our crystals,we fabricated a planar detector withμτ_(e)of(1.11±0.04)×10^(-4)cm^(2)∕V,which performed with a decent radiation-detection feature.This study demonstrates that the vapor-pressure-controlled VGF method is a viable technical route for fabricating detector-grade CdTe crystals.
基金supported by the Institute for Nuclear Research of the Russian Academy of Sciences。
文摘A time-of-flight Highly Granular Neutron Detector(HGND)with a multilayer longitudinal structure of interleaved absorber and scintillator plates,high transverse granularity,and time resolution of approximately 150 ps is currently under development.The detector is designed to identify neutrons produced in nucleus-nucleus collisions and measure neutron kinetic energies of 0.3-4 GeV by the time-of-flight method in the BM@N experiment at the NICA accelerator complex at JINR.To validate the concept of full-scale HGND,a compact HGND prototype was first designed and built,and its performance was studied in the BM@N experiment.The acceptance of the HGND prototype and the detection efficiency of forward neutrons emitted in hadronic fragmentation and electromagnetic dissociation(EMD)of 3.8A GeV124Xe projectiles interacting with a CsI target were calculated by means of the DCM-QGSM-SMM and RELDIS models,respectively.The energy distributions of the forward spectator neutrons and neutrons from the EMD were measured and compared with the simulations.The developed methods will be used to calibrate the full-scale HGND and study its efficiency.
基金Supported by the National Basic Research Program of China ("973"Program)(2006CB601201)~~
文摘In high-resolution cone-beam computed tomography (CBCT) using the flat-panel detector, imperfect or defect detector elements cause ring artifacts due to the none-uniformity of their X-ray response. They often disturb the image quality. A dedicated fitting correction method for high-resolution micro-CT is presented. The method converts each elementary X-ray response curve to an average one, and eliminates response inconsistency among pixels. Other factors of the method are discussed, such as the correction factor variability by different sampling frames and nonlinear factors over the whole spectrum. Results show that the noise and artifacts are both reduced in reconstructed images
基金supported by the State Key Development Program for Basic Research of China (Nos. 2008CB717803, 2009GB107001,2007CB209903)the Research Fund for the Doctoral Program of Higher Education of China (No. 200610011023)National Natural Science Foundation of China (No. 10875002)
文摘An accurate energy calibration of a 5"× 2" BC501A liquid scintillator-based neutron detector by means of photon sources and the unfolding of pulse height spectra are described. The photon responses were measured with 22Na, 137Cs and 54Mn photon sources and simulated using the GRESP code, which was developed at the Physiknlisch Technische Bundesanstalt in Germany. Pulse height spectra produced by three different photon sources were employed to investigate the effects of the unfolding techniques. It was found that the four unfolding codes of the HEPRO and UMG3.3 packages, including GRAVEL, UNFANA, MIEKE and MAXED, performed well with the test spectra and produced generally consistent results. They could therefore be used to obtain neutron energy spectra in toknmak experiments.
基金supported by the National Natural Science Foundation of China(Nos.12205190,11805121)the Science and Technology Commission of Shanghai Municipality(No.21ZR1435400).
文摘The uncertainty of nuclide libraries in the analysis of the gamma spectra of low-and intermediate-level radioactive waste(LILW)using existing methods produces unstable results.To address this problem,a novel spectral analysis method is proposed in this study.In this method,overlapping peaks are located using a continuous wavelet transform.An improved quadratic convolution method is proposed to calculate the widths of the peaks and establish a fourth-order filter model to estimate the Compton edge baseline with the overlapping peaks.Combined with the adaptive sensitive nonlinear iterative peak,this method can effectively subtracts the background.Finally,a function describing the peak shape as a filter is used to deconvolve the energy spectrum to achieve accurate qualitative and quantitative analyses of the nuclide without the aid of a nuclide library.Gamma spectrum acquisition experiments for standard point sources of Cs-137 and Eu-152,a segmented gamma scanning experiment for a 200 L standard drum,and a Monte Carlo simulation experiment for triple overlapping peaks using the closest energy of three typical LILW nuclides(Sb-125,Sb-124,and Cs-134)are conducted.The results of the experiments indicate that(1)the novel method and gamma vision(GV)with an accurate nuclide library have the same spectral analysis capability,and the peak area calculation error is less than 4%;(2)compared with the GV,the analysis results of the novel method are more stable;(3)the novel method can be applied to the activity measurement of LILW,and the error of the activity reconstruction at the equivalent radius is 2.4%;and(4)The proposed novel method can quantitatively analyze all nuclides in LILW without a nuclide library.This novel method can improve the accuracy and precision of LILW measurements,provide key technical support for the reasonable disposal of LILW,and ensure the safety of humans and the environment.
基金the National Natural Science Foundation of China (Grant No. 11403050)。
文摘As the areas of CCD detectors and CCD mosaics have become larger and larger,the number of readout channels in astronomical cameras has increased accordingly to keep the image readout time within an acceptable range.For the large area cameras or the mosaic cameras,the analog Correlated Double Sampling(aCDS)circuit used in traditional astronomical cameras for suppressing readout noise is difficult to integrate into the camera controllers within the constraints of the space and energy consumption.Recently,digital CDS(dCDS)technology has been developed to solve this problem,which also offers novel analysis and noise suppression methods.In this study,a mathematical model is presented to conveniently analyze the frequency characteristic of a dCDS circuit,which is then simulated by a numerical method for investigating the noise suppression capability with different sampling weights.Importantly,using this model,the extreme point with lowest readout noise can be predicted for a certain dCDS model;and for a specific CCD readout frequency,readout noise can be suppressed by selecting the proper dCDS model.A testing system is then constructed for validating the efficiency of the proposed method.
基金supported by the Major program of Natural Science Foundation of Shandong Province(No.ZR2020ZD30)the National Natural Science Foundation of China(Nos.11775133,U2167202,U1432119).
文摘A particle detector array designed for light-charged particles, known as the CsI-bowl, was built for exit channel selection for in-beam γ-ray spectroscopy experiments. This device is composed of 64 CsI(Tl) detectors, organized in a structure reminiscent of a tea-bowl. High quantum efficiency photodiodes, characterized by their minimal mass, were employed to collect scintillation light. Its design, construction, particle identification resolution, and its effectiveness in relation to exit channel selection are described in this paper. In source tests, the optimal figure of merit for the identification of α-particles and γ-rays using the charge comparison method was found to be 3.3 and 12.1 for CsI detectors coupled to photodiodes and avalanche photodiodes, respectively. The CsI-bowl demonstrated effectiveness in identifying particles, specifically the emission of protons and α-particles in the58Ni(19F, xpyn) fusion–evaporation reaction, thereby enabling the selection of the desired exit channels.
基金Supported by the National Basic Research Program of China under Grant No. 2003 CB 716300the National Natural Science Foundation of China under Grant No. 10575140+2 种基金CAEP Foundation under Grant No. 2008T0401 and 2008T0402Chongqing University Postgraduates Science and Innovation Fund, Project No. 200811B1A0100299Chinese State Scholarship Fund
文摘This paper focuses on the relic gravity waves produced during the transition from a radiation-dominated inflationary phase to a dust-dominated Friedman-Robertson-Walker-type expansion. We discuss how to investigate the spectral energy density by the latest space-based CWs detectors at f =0.1 Hz (i.e. DECICO). In the case of power-law and exponential inflation, we apply the cross-correlation method to the latest detector and get the time dependence of the very early Hubble pararneter.
基金supported by the Strategic Priority Program on Space Science,the Chinese Academy of Sciences,grant Nos.XDA15360102,XDA15360300 and E02212A02Sthe National Natural Science Foundation of China(Project:12061131007)。
文摘The Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)mission is designed to monitor the Gamma-Ray Bursts(GRBs)associated with gravitational waves and other high-energy transient sources.The mission consists of two microsatellites which are planned to operate at the opposite sides of the Earth.Each GECAM satellite could detect and localize GRBs in about 8 keV-5 MeV with its 25 Gamma-Ray Detectors(GRDs).In this work,we report the in-flight energy calibration of GRDs using the characteristic gamma-ray lines in the background spectra,and show their performance evolution during the commissioning phase.Besides,a preliminary cross-calibration of energy response with Fermi GBM data is also presented,validating the energy response of GRDs.
基金financially supported by“Laval Agglomération”and the“Conseil Départemental de la Mayenne”.
文摘A high-performance liquid chromatography analysis method with an evaporative light-scattering detector has been developed for the separation and quantitative analysis of free fatty acids in biological matrices. Core-shell reversed-phase high-performance liquid chromatography separation of 10 free fatty acids is achieved within 10.5 min using a methanol/water (0.05% trifluoroacetic acid) eluent gradient. After optimization, the drift tube and nebulization temperature of the evaporative light-scattering detector was set at 35°C, nitrogen flow-rate at 1.1 standard liter per minute and column temperature at 25°C. All calibration curves showed good regression (r2 > 0.9975). A validation procedure following the International Conference on Harmonisation guidelines was implemented to certify the method. Relative standard deviations did not exceed 1.5% and 4.25% for repeatability and reproducibility respectively.
基金supported by the National Key Scientific Instruments To Develop Dedicated(2013YQ090811)
文摘An electronic personal dosimeter mainly uses a Si-PIN photodiode as X-and gamma-ray detectors.The photon energy response of this instrument is inconsistent in the case of no correction,which seriously affects the accurate monitoring of personal dose equivalent H_p(10)parameters for radiation workers.For this reason,in this paper we propose a method of combining composite screen detection technology,multichannel measurement technology,and the channel ratio method to achieve accurate measurement of the personal dose equivalent parameters.According to China National Standard GB/T 13161-2003 and National Verification Regulation JJG 1009-2006,the instrument was tested in the energy range between 48 keV and 1.25 MeV.The experimental results showed that the difference of energy response to ^(137)C_S corrected by the new method was almost constant within ±6.0%,which fulfilled the ±30% requirement of GB/T 13161-2003 and JJG1009-2006.Meanwhile,the method proposed obtained energy information regarding the radiation field.