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A CLOUD-RESOLVING MODELING STUDY OF SURFACE RAINFALL PROCESSES ASSOCIATED WITH LANDFALLING TYPHOON KAEMI(2006) 被引量:8
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作者 崔晓鹏 许凤雯 《Journal of Tropical Meteorology》 SCIE 2009年第2期181-191,共11页
The detailed surface rainfall processes associated with landfalling typhoon Kaemi(2006) are investigated based on hourly data from a two-dimensional cloud-resolving model simulation. The model is integrated for 6 da... The detailed surface rainfall processes associated with landfalling typhoon Kaemi(2006) are investigated based on hourly data from a two-dimensional cloud-resolving model simulation. The model is integrated for 6 days with imposed large-scale vertical velocity, zonal wind, horizontal temperature and vapor advection from National Center for Environmental Prediction (NCEP) / Global Data Assimilation System (GDAS) data. The simulation data are validated with observations in terms of surface rain rate. The Root-Mean-Squared (RMS) difference in surface rain rate between the simulation and the gauge observations is 0.660 mm h^-1, which is smaller than the standard deviations of both the simulated rain rate (0.753 mm h^-1) and the observed rain rate (0.833 mm h^-1). The simulation data are then used to study the physical causes associated with the detailed surface rainfall processes during the landfall. The results show that time averaged and model domain-mean Ps mainly comes from large-scale convergence (QWVF) and local vapor loss (positive QWVT). Large underestimation (about 15%) of Ps will occur if QWVT and QCM (cloud source/sink) are not considered as contributors to Ps ,QWVF accounts for the variation of P during most of the integration time, while it is not always a contributor to Ps,Sometimes surface rainfall could occur when divergence is dominant with local vapor loss to be a contributor to Ps - Surface rainfall is a result ofmulti-timescale interactions. QWVE possesses the longest time scale and the lowest frequeney the second and QCM of variation with time and may exert impact on P on longer time scales. QWVF possesses longest time scale and lowest frequency and can explain most of the variation of Ps. QWVT possess shorter time scales and higher frequencies, which can explain more detailed variations in Ps. Partitioning analysis shows that stratiform rainfall is dominant from the morning of 26 July till the late night of 27 July. After that, convective rainfall dominates till about 1000 LST 28 July. Before 28 July, the variations of QWVT in rainfall-free regions contribute less to that of the domain-mean QWVT while after that they contribute much, which is consistent to the corresponding variations in their fractional coverage. The variations of QWVF in rainfall regions are the main contributors to that of the domain-mean QWVF, then the main contributors to the surface rain rate before the afternoon of 28 July. 展开更多
关键词 surface rainfall processes landfalling typhoon cloud-resolving modeling study
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A Review of Cloud-Resolving Model Studies of Convective Processes 被引量:4
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作者 Xiaoqing WU Xiaofan LI 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2008年第2期202-212,共11页
Convective processes affect large-scale environments through cloud-radiation interaction, cloud micro- physical processes, and surface rainfall processes. Over the last three decades, cloud-resolving models (CRMs) h... Convective processes affect large-scale environments through cloud-radiation interaction, cloud micro- physical processes, and surface rainfall processes. Over the last three decades, cloud-resolving models (CRMs) have demonstrated to be capable of simulating convective-radiative responses to an imposed large-scale forcing. The CRM-produced cloud and radiative properties have been utilized to study the convective- related processes and their ensemble effects on large-scale circulations. This review the recent progress on the understanding of convective processes with the use of CRM simulations, including precipitation processes; cloud microphysical and radiative processes; dynamical processes; precipitation efficiency; diurnal variations of tropical oceanic convection; local-scale atmosphere-ocean coupling processes; and tropical convective-radiative equilibrium states. Two different ongoing applications of CRMs to general circulation models (GCMs) are discussed: replacing convection and cloud schemes for studying the interaction between cloud systems and large-scale circulation, and improving the schemes for climate simulations. 展开更多
关键词 cloud-resolving models (CRMs) convective processes simulations of convection and clouds
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Water Vapor,Cloud,and Surface Rainfall Budgets Associated with the Landfall of Typhoon Krosa(2007):A Two-Dimensional Cloud-Resolving Modeling Study 被引量:3
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作者 岳彩军 寿绍文 Xiaofan LI 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2009年第6期1198-1208,共11页
Water vapor, cloud, and surface rainfall budgets associated with the landfall of Typhoon Krosa on 6-8 October 2007 are analyzed based on a two-dimensional cloud-resolving model simulation. The model is integrated with... Water vapor, cloud, and surface rainfall budgets associated with the landfall of Typhoon Krosa on 6-8 October 2007 are analyzed based on a two-dimensional cloud-resolving model simulation. The model is integrated with imposed zonally-uniform vertical velocity, zonal wind, horizontal temperature, and vapor advection from NCEP/Global Data Assimilation System (GDAS) data. The simulation data that are validated with observations are examined to study physical causes associated with surface rainfall processes during the landfall. The time- and domain-mean analysis shows that when Krosa approached the eastern coast of China on 6 October, the water vapor convergence over land caused a local atmospheric moistening and a net condensation that further produced surface rainfall and an increase of cloud hydrometeor concentration. Meanwhile, latent heating was balanced by advective cooling and a local atmospheric warming. One day later, the enhancement of net condensation led to an increase of surface rainfall and a local atmospheric drying, while the water vapor convergence weakened as a result of the landfall-induced deprivation of water vapor flux. At the same time, the latent heating is mainly compensated the advective cooling. Further weakening of vapor convergence on 8 October enhanced the local atmospheric drying while the net condensation and associated surface rainfall was maintained. The latent heating is balanced by advective cooling and a local atmospheric cooling. 展开更多
关键词 BUDGET cloud-resolving modeling Typhoon Krosa
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Impacts of Initial Conditions on Cloud-Resolving Model Simulations 被引量:3
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作者 高守亭 Xiaofan LI 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2008年第5期737-747,共11页
Impacts of initial conditions on cloud-resolving model simulations are investigated using a series of sensitivity experiments. Five experiments with perturbed initial temperature, moisture, and cloud conditions are co... Impacts of initial conditions on cloud-resolving model simulations are investigated using a series of sensitivity experiments. Five experiments with perturbed initial temperature, moisture, and cloud conditions are conducted and compared to the control experiment. The model is forced by the large-scale vertical velocity and zonal wind observed and derived from NCEP/Global Data Assimilation System (GDAS). The results indicate that model predictions of rainfall are much more sensitive to the initial conditions than those of temperature and moisture. Further analyses of the surface rainfall equation and the moisture and cloud hydrometeor budgets reveal that the calculations of vapor condensation and deposition rates in the model account for the large sensitivities in rainfall simulations. 展开更多
关键词 cloud-resolving model initial conditions sensitivity experiments
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Effects of Doubled Carbon Dioxide on Rainfall Responses to Large-Scale Forcing:A Two-Dimensional Cloud-Resolving Modeling Study 被引量:2
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作者 LI Xiaofan SHEN Xinyong LIU Jia 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2014年第3期525-531,共7页
ABSTRACT Rainfall responses to doubled atmospheric carbon dioxide concentration were investigated through the analysis of two pairs of two-dimensional cloud-resolving model sensitivity experiments. One pair of experi... ABSTRACT Rainfall responses to doubled atmospheric carbon dioxide concentration were investigated through the analysis of two pairs of two-dimensional cloud-resolving model sensitivity experiments. One pair of experiments simulated pre-summer heavy rainfall over southern China around the summer solstice, whereas the other pair of experiments simulated tropical rainfall around the winter solstice. The analysis of the time and model domain mean heat budget revealed that the enhanced local atmospheric warming was associated with doubled carbon dioxide through the weakened infrared radiative cooling during the summer solstice. The weakened mean pre-summer rainfall corresponded to the weakened mean infrared radiative cooling. Doubled carbon dioxide increased the mean tropical atmospheric warming via the enhanced mean latent heat in correspondence with the strengthened mean infrared radiative cooling during the winter solstice. The enhanced mean tropical rainfall was associated with the increased mean latent heat. 展开更多
关键词 doubled carbon dioxide radiation latent heat CONDENSATION RAINFALL cloud-resolving model simulation
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Effects of Vertical Wind Shear on the Pre-Summer Heavy Rainfall Budget:A Cloud-Resolving Modeling Study
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作者 SHEN Xin-Yong QING Tao +1 位作者 HUANG Wen-Yan LI Xiao-Fan 《Atmospheric and Oceanic Science Letters》 CSCD 2013年第1期44-51,共8页
This study investigates the effects of vertical wind shear on the torrential rainfall response to the large-scale forcing using a rainfall separation analysis of a pair of two-dimensional cloud-resolving model sensiti... This study investigates the effects of vertical wind shear on the torrential rainfall response to the large-scale forcing using a rainfall separation analysis of a pair of two-dimensional cloud-resolving model sensitivity experiments for a pre-summer heavy rainfall event over southern China from 3-8 June 2008 coupled with National Centers for Environmental Prediction(NCEP)/Global Data Assimilation System(GDAS) data.The rainfall partitioning analysis based on the surface rainfall budget indicates that the exclusion of vertical wind shear decreases the contribution to total rainfall from the largest contributor,which is the rainfall associated with local atmospheric drying,water vapor divergence,and hydrometeor loss/convergence,through the reduction of the rainfall area and reduced rainfall during the rainfall event.The removal of vertical wind shear increases the contribution to total rainfall from the rainfall associated with local atmospheric drying,water vapor convergence,and hydrometeor loss/convergence through the expansion of the rainfall area and enhanced rainfall.The elimination of vertical wind shear enhances heavy rainfall and expands its area,whereas it reduces moderate rainfall and its area. 展开更多
关键词 cloud-resolving model simulation vertical wind shear rainfall partitioning surface rainfall budget
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Improving Representation of Tropical Cloud Overlap in GCMs Based on Cloud-Resolving Model Data
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作者 Xianwen JING Hua ZHANG +1 位作者 Masaki SATOH Shuyun ZHAO 《Journal of Meteorological Research》 SCIE CSCD 2018年第2期233-245,共13页
The decorrelation length(Lcf) has been widely used to describe the behavior of vertical overlap of clouds in general circulation models(GCMs); however, it has been a challenge to associate Lcf with the large-scale... The decorrelation length(Lcf) has been widely used to describe the behavior of vertical overlap of clouds in general circulation models(GCMs); however, it has been a challenge to associate Lcf with the large-scale meteorological conditions during cloud evolution. This study explored the relationship between Lcf and the strength of atmospheric convection in the tropics based on output from a global cloud-resolving model. Lcf tends to increase with vertical velocity in the mid-troposphere(w500) at locations of ascent, but shows little or no dependency on w500 at locations of descent. A representation of Lcf as a function of vertical velocity is obtained, with a linear regression in ascending regions and a constant value in descending regions. This simple and dynamic-related representation of Lcf leads to a significant improvement in simulation of both cloud cover and radiation fields compared with traditional overlap treatments. This work presents a physically justifiable approach to depicting cloud overlap in the tropics in GCMs. 展开更多
关键词 cloud overlap decorrelation length cloud-resolving model Nonhydrostatic Icosahedral Atmospheric model(NICAM)
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CLOUD-RESOLVING MODELING OF CONVECTIVE PROCESSES
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作者 Mitchell Moncrieff 《Acta meteorologica Sinica》 SCIE 2009年第1期128-128,共1页
Recent decades have witnessed the rapid development of cloud-system resolving models (CRM), which are now capable of simulating cloud systems and accompanying interactions on scales up to global, albeit in the latte... Recent decades have witnessed the rapid development of cloud-system resolving models (CRM), which are now capable of simulating cloud systems and accompanying interactions on scales up to global, albeit in the latter application small- scale convection (cumulus) remains unresolved. The implication of such a truncation is not understood. The CRM approach has its roots in non-hydrostatic cloud models developed a generation ago for simulating individual cumulonimbus in integrations lasting about an hour Advances in computer capacity enable CRMs to be run with progressively larger computational domains and be integrated for weeks or months, 展开更多
关键词 CRM cloud-resolving modelING OF CONVECTIVE PROCESSES
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A Modeling Analysis of Rainfall and Water Cycle by the Cloud-resolving WRF Model over the Western North Pacific 被引量:2
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作者 高文华 隋中兴 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2013年第6期1695-1711,共17页
Simulated regional precipitation, especially extreme precipitation events, and the regional hydrologic budgets over the western North Pacific region during the period from May to June 2008 were investigated with the h... Simulated regional precipitation, especially extreme precipitation events, and the regional hydrologic budgets over the western North Pacific region during the period from May to June 2008 were investigated with the high-resolution (4-km grid spacing) Weather Research and Forecast (WRF v3.2.1) model with explicit cloud microphysics. The model initial and boundary conditions were derived from the National Centers for Environmental Prediction/Department of Energy (NCEP/DOE) Reanalysis 2 data. The model precipitation results were evaluated against the Tropical Rainfall Measuring Mission (TRMM) Multisatellite Precipitation Analysis 3B42 product. The results show that the WRF simulations can reason- ably reproduce the spatial distributions of daily mean precipitation and rainy days. However, the simulated frequency distributions of rainy days showed an overestimation of light precipitation, an underestimation of moderate to heavy precipitation, but a good representation of extreme precipitation. The downscaling approach was able to add value to the very heavy precipitation over the ocean since the convective processes are resolved by the high-resolution cloud-resolving model. Moreover, the water vapor budget analysis indi- cates that heavy precipitation is contributed mostly by the stronger moisture convergence; whereas, in less convective periods, the precipitation is more influenced by the surface evaporation. The simulated water vapor budgets imply the importance in the tropical monsoon region of cloud microphysics that affects the precipitation, atmospheric latent heating and, subsequently, the large-scale circulation. 展开更多
关键词 cloud-resolving WRF PRECIPITATION western North Pacific
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Ecological Dynamics of a Logistic Population Model with Impulsive Age-selective Harvesting
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作者 DAI Xiangjun JIAO Jianjun 《应用数学》 北大核心 2026年第1期72-79,共8页
In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asy... In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asymptotic stability of the trivial solution and the positive periodic solution.Finally,numerical simulations are presented to validate our results.Our results show that age-selective harvesting is more conducive to sustainable population survival than non-age-selective harvesting. 展开更多
关键词 The logistic population model Selective harvesting Asymptotic stability EXTINCTION
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Modeling of Precipitation over Africa:Progress,Challenges,and Prospects
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作者 A.A.AKINSANOLA C.N.WENHAJI +21 位作者 R.BARIMALALA P.-A.MONERIE R.D.DIXON A.T.TAMOFFO M.O.ADENIYI V.ONGOMA I.DIALLO M.GUDOSHAVA C.M.WAINWRIGHT R.JAMES K.C.SILVERIO A.FAYE S.S.NANGOMBE M.W.POKAM D.A.VONDOU N.C.G.HART I.PINTO M.KILAVI S.HAGOS E.N.RAJAGOPAL R.K.KOLLI S.JOSEPH 《Advances in Atmospheric Sciences》 2026年第1期59-86,共28页
In recent years,there has been an increasing need for climate information across diverse sectors of society.This demand has arisen from the necessity to adapt to and mitigate the impacts of climate variability and cha... In recent years,there has been an increasing need for climate information across diverse sectors of society.This demand has arisen from the necessity to adapt to and mitigate the impacts of climate variability and change.Likewise,this period has seen a significant increase in our understanding of the physical processes and mechanisms that drive precipitation and its variability across different regions of Africa.By leveraging a large volume of climate model outputs,numerous studies have investigated the model representation of African precipitation as well as underlying physical processes.These studies have assessed whether the physical processes are well depicted and whether the models are fit for informing mitigation and adaptation strategies.This paper provides a review of the progress in precipitation simulation overAfrica in state-of-the-science climate models and discusses the major issues and challenges that remain. 展开更多
关键词 RAINFALL MONSOON climate modeling CORDEX CMIP6 convection-permitting models
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Design optimization and FEA of B-6 and B-7 levels ballistics armor:A modelling approach
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作者 Muhammad Naveed CHU Jinkui +1 位作者 Atif Ur Rehman Arsalan Hyder 《大连理工大学学报》 北大核心 2026年第1期66-77,共12页
Utilizing finite element analysis,the ballistic protection provided by a combination of perforated D-shaped and base armor plates,collectively referred to as radiator armor,is evaluated.ANSYS Explicit Dynamics is empl... Utilizing finite element analysis,the ballistic protection provided by a combination of perforated D-shaped and base armor plates,collectively referred to as radiator armor,is evaluated.ANSYS Explicit Dynamics is employed to simulate the ballistic impact of 7.62 mm armor-piercing projectiles on Aluminum AA5083-H116 and Steel Secure 500 armors,focusing on the evaluation of material deformation and penetration resistance at varying impact points.While the D-shaped armor plate is penetrated by the armor-piercing projectiles,the combination of the perforated D-shaped and base armor plates successfully halts penetration.A numerical model based on the finite element method is developed using software such as SolidWorks and ANSYS to analyze the interaction between radiator armor and bullet.The perforated design of radiator armor is to maintain airflow for radiator function,with hole sizes smaller than the bullet core diameter to protect radiator assemblies.Predictions are made regarding the brittle fracture resulting from the projectile core′s bending due to asymmetric impact,and the resulting fragments failed to penetrate the perforated base armor plate.Craters are formed on the surface of the perforated D-shaped armor plate due to the impact of projectile fragments.The numerical model accurately predicts hole growth and projectile penetration upon impact with the armor,demonstrating effective protection of the radiator assemblies by the radiator armor. 展开更多
关键词 radiator armor ballistics simulation Johnson-Cook model armor-piercing projectile perforated D-shaped armor plate
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Do Higher Horizontal Resolution Models Perform Better?
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作者 Shoji KUSUNOKI 《Advances in Atmospheric Sciences》 2026年第1期259-262,共4页
Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(... Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)]. 展开更多
关键词 enhancing model resolution refinement data assimilation systems section climate model climate projection higher horizontal resolution seasonal forecasting simulation seasonal migration rain bands model resolution
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A Predictive Model for the Elastic Modulus of High-Strength Concrete Based on Coarse Aggregate Characteristics
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作者 LI Liangshun LI Huajian +2 位作者 HUANG Fali YANG Zhiqiang DONG Haoliang 《Journal of Wuhan University of Technology(Materials Science)》 2026年第1期121-137,共17页
To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the stre... To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the strength and elastic modulus of mortar and concrete prepared with mechanism aggregates of the corresponding lithology,and the stress-strain curves of concrete were investigated.In this paper,a coarse aggregate and mortar matrix bonding assumption is proposed,and a prediction model for the elastic modulus of mortar is established by considering the lithology of the mechanism sand and the slurry components.An equivalent coarse aggregate elastic modulus model was established by considering factors such as coarse aggregate particle size,volume fraction,and mortar thickness between coarse aggregates.Based on the elastic modulus of the equivalent coarse aggregate and the remaining mortar,a prediction model for the elastic modulus of the two and three components of concrete in series and then in parallel was established,and the predicted values differed from the measured values within 10%.It is proposed that the coarse aggregate elastic modulus in highstrength concrete is the most critical factor affecting the elastic modulus of concrete,and as the coarse aggregate elastic modulus increases by 27.7%,the concrete elastic modulus increases by 19.5%. 展开更多
关键词 elastic modulus prediction model MINERALOGICAL influence mechanism
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Global Stability of Traveling Wavefronts for a Belousov-Zhabotinsky Model with Mixed Nonlocal and Degenerate Diffusions
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作者 Yuting YANG Guobao ZHANG 《Journal of Mathematical Research with Applications》 2026年第1期87-102,共16页
In this paper,we are concerned with the stability of traveling wavefronts of a Belousov-Zhabotinsky model with mixed nonlocal and degenerate diffusions.Such a system can be used to study the competition among nonlocal... In this paper,we are concerned with the stability of traveling wavefronts of a Belousov-Zhabotinsky model with mixed nonlocal and degenerate diffusions.Such a system can be used to study the competition among nonlocally diffusive species and degenerately diffusive species.We prove that the traveling wavefronts are exponentially stable,when the initial perturbation around the traveling waves decays exponentially as x→-∞,but in other locations,the initial data can be arbitrarily large.The adopted methods are the weighted energy with the comparison principle and squeezing technique. 展开更多
关键词 Belousov-Zhabotinsky model nonlocal diffusion stability comparison principle weighted energy
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An effective deep-learning prediction of Arctic sea-ice concentration based on the U-Net model
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作者 Yifan Xie Ke Fan +2 位作者 Hongqing Yang Yi Fan Shengping He 《Atmospheric and Oceanic Science Letters》 2026年第1期34-40,共7页
Current shipping,tourism,and resource development requirements call for more accurate predictions of the Arctic sea-ice concentration(SIC).However,due to the complex physical processes involved,predicting the spatiote... Current shipping,tourism,and resource development requirements call for more accurate predictions of the Arctic sea-ice concentration(SIC).However,due to the complex physical processes involved,predicting the spatiotemporal distribution of Arctic SIC is more challenging than predicting its total extent.In this study,spatiotemporal prediction models for monthly Arctic SIC at 1-to 3-month leads are developed based on U-Net-an effective convolutional deep-learning approach.Based on explicit Arctic sea-ice-atmosphere interactions,11 variables associated with Arctic sea-ice variations are selected as predictors,including observed Arctic SIC,atmospheric,oceanic,and heat flux variables at 1-to 3-month leads.The prediction skills for the monthly Arctic SIC of the test set(from January 2018 to December 2022)are evaluated by examining the mean absolute error(MAE)and binary accuracy(BA).Results showed that the U-Net model had lower MAE and higher BA for Arctic SIC compared to two dynamic climate prediction systems(CFSv2 and NorCPM).By analyzing the relative importance of each predictor,the prediction accuracy relies more on the SIC at the 1-month lead,but on the surface net solar radiation flux at 2-to 3-month leads.However,dynamic models show limited prediction skills for surface net solar radiation flux and other physical processes,especially in autumn.Therefore,the U-Net model can be used to capture the connections among these key physical processes associated with Arctic sea ice and thus offers a significant advantage in predicting Arctic SIC. 展开更多
关键词 Arctic sea-ice concentration Deep-learning prediction U-Net model CFSv2 NorCPM
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Tail clamping induces anxiety-like behaviors and visceral hypersensitivity in rat models of non-erosive reflux disease
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作者 Mi Lv Xin Liu +6 位作者 Kai-Yue Huang Yu-Xi Wang Zheng Wang Li-Li Han Hui Che Lin Lv Feng-Yun Wang 《World Journal of Psychiatry》 2026年第1期356-368,共13页
BACKGROUND Non-erosive reflux disease(NERD),the main gastroesophageal reflux subtype,features reflux symptoms without mucosal damage.Anxiety links to visceral hypersensitivity in NERD,yet mechanisms and animal models ... BACKGROUND Non-erosive reflux disease(NERD),the main gastroesophageal reflux subtype,features reflux symptoms without mucosal damage.Anxiety links to visceral hypersensitivity in NERD,yet mechanisms and animal models are unclear.AIM To establish a translational NERD rat model with anxiety comorbidity via tail clamping and study corticotropin-releasing hormone(CRH)-mediated neuroimmune pathways in visceral hypersensitivity and esophageal injury.METHODS Sprague-Dawley(SD)and Wistar rats were grouped into sham,model,and modified groups(n=10 each).The treatments for the modified groups were as follows:SD rats received ovalbumin/aluminum hydroxide suspension+acid perfusion±tail clamping(40 minutes/day for 7 days),while Wistar rats received fructose water+tail clamping.Esophageal pathology,visceral sensitivity,and behavior were assessed.Serum CRH,calcitonin gene-related peptide(CGRP),5-hydroxytryptamine(5-HT),and mast cell tryptase(MCT)and central amygdala(CeA)CRH mRNA were measured via ELISA and qRT-PCR.RESULTS Tail clamping induced anxiety,worsening visceral hypersensitivity(lower abdominal withdrawal reflex thresholds,P<0.05)and esophageal injury(dilated intercellular spaces and mitochondrial edema).Both models showed raised serum CRH,CGRP,5-HT,and MCT(P<0.01)and CeA CRH mRNA expression(P<0.01).Behavioral tests confirmed anxiety-like phenotypes.NERD-anxiety rats showed clinical-like symptom severity without erosion.CONCLUSION Tail clamping induces anxiety in NERD models,worsening visceral hypersensitivity via CRH neuroimmune dysregulation,offering a translational model and highlighting CRH as a treatment target. 展开更多
关键词 Non-erosive reflux disease Anxiety and depression Animal model Tail-clamping Corticotropin hormones
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Processing map for oxide dispersion strengthening Cu alloys based on experimental results and machine learning modelling
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作者 Le Zong Lingxin Li +8 位作者 Lantian Zhang Xuecheng Jin Yong Zhang Wenfeng Yang Pengfei Liu Bin Gan Liujie Xu Yuanshen Qi Wenwen Sun 《International Journal of Minerals,Metallurgy and Materials》 2026年第1期292-305,共14页
Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening pa... Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening particles also deteriorates the processability and it is of great importance to establish accurate processing maps to guide the thermomechanical processes to enhance the formability.In this study,we performed particle swarm optimization-based back propagation artificial neural network model to predict the high temperature flow behavior of 0.25wt%Al2O3 particle-reinforced Cu alloys,and compared the accuracy with that of derived by Arrhenius-type constitutive model and back propagation artificial neural network model.To train these models,we obtained the raw data by fabricating ODS Cu alloys using the internal oxidation and reduction method,and conducting systematic hot compression tests between 400 and800℃with strain rates of 10^(-2)-10 S^(-1).At last,processing maps for ODS Cu alloys were proposed by combining processing parameters,mechanical behavior,microstructure characterization,and the modeling results achieved a coefficient of determination higher than>99%. 展开更多
关键词 oxide dispersion strengthened Cu alloys constitutive model machine learning hot deformation processing maps
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Growing a Rural Future--A young Ugandan channels insights from China’s model villages to build a more resilient,cooperative and forward-looking Busoga
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作者 LI XIAOYU 《ChinAfrica》 2026年第1期56-57,共2页
In the lush heart of Uganda’s Busoga sub-region,Isaac Imaka is charting a new course for rural development.After seven years in national media,he left the newsroom and stepped into the soil.The former reporter with t... In the lush heart of Uganda’s Busoga sub-region,Isaac Imaka is charting a new course for rural development.After seven years in national media,he left the newsroom and stepped into the soil.The former reporter with the Daily Monitor was driven by the belief that communities like his in Jinja North deserved more than chronic poverty and hand-to-mouth survival. 展开更多
关键词 community resilience Uganda rural development model villages rural future Busoga sub region cooperative development rural journalism
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Effects of noninvasive brain stimulation on motor functions in animal models of ischemia and trauma in the central nervous system
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作者 Seda Demir Gereon R.Fink +1 位作者 Maria A.Rueger Stefan J.Blaschke 《Neural Regeneration Research》 2026年第4期1264-1276,共13页
Noninvasive brain stimulation techniques offer promising therapeutic and regenerative prospects in neurological diseases by modulating brain activity and improving cognitive and motor functions.Given the paucity of kn... Noninvasive brain stimulation techniques offer promising therapeutic and regenerative prospects in neurological diseases by modulating brain activity and improving cognitive and motor functions.Given the paucity of knowledge about the underlying modes of action and optimal treatment modalities,a thorough translational investigation of noninvasive brain stimulation in preclinical animal models is urgently needed.Thus,we reviewed the current literature on the mechanistic underpinnings of noninvasive brain stimulation in models of central nervous system impairment,with a particular emphasis on traumatic brain injury and stroke.Due to the lack of translational models in most noninvasive brain stimulation techniques proposed,we found this review to the most relevant techniques used in humans,i.e.,transcranial magnetic stimulation and transcranial direct current stimulation.We searched the literature in Pub Med,encompassing the MEDLINE and PMC databases,for studies published between January 1,2020 and September 30,2024.Thirty-five studies were eligible.Transcranial magnetic stimulation and transcranial direct current stimulation demonstrated distinct strengths in augmenting rehabilitation post-stroke and traumatic brain injury,with emerging mechanistic evidence.Overall,we identified neuronal,inflammatory,microvascular,and apoptotic pathways highlighted in the literature.This review also highlights a lack of translational surrogate parameters to bridge the gap between preclinical findings and their clinical translation. 展开更多
关键词 noninvasive brain stimulation preclinical modeling STROKE transcranial direct current stimulation transcranial magnetic stimulation traumatic brain injury
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