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Parameter optimization for torsion spring of deployable solar array system with multiple clearance joints considering rigid–flexible coupling dynamics 被引量:3
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作者 Yuanyuan LI Meng LI +2 位作者 Yufei LIU Xinyu GENG Chengbo CUI 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2022年第3期509-524,共16页
In this paper,four novel evaluation indices and corresponding hierarchical optimization strategies are proposed for a deployable solar array system considering panel flexibility and joint clearance.The deployable sola... In this paper,four novel evaluation indices and corresponding hierarchical optimization strategies are proposed for a deployable solar array system considering panel flexibility and joint clearance.The deployable solar array model consists of a rigid main-body,two panels and four key mechanisms,containing torsion spring mechanism,closed cable loop mechanism,latch mechanism and attitude adjustment mechanism.Rigid and flexible components are established by Nodal Coordinate Formulation and Absolute Nodal Coordinate Formulation,respectively.The clearance joint model is described by nonlinear contact force model and amendatory Coulomb friction model.The latch time,stabilization time,maximum contact force and impulse sum of the contact force of the solar array system are selected as the four novel evaluation indices to represent the complex dynamic responses of a deployable solar array with clearance joints instead of the lock torque widely used in conventional works.To eliminate the gross errors caused by the nonlinear and nonsmooth mechanical properties,a hierarchical optimization strategy based on an adaptive simulated annealing algorithm and a nondominated sorting genetic algorithm is adopted for the solar array system with clearance joints.Results indicate that the effects of panel flexibility on the evaluation index responses and design optimization of the solar array system cannot be neglected.Besides,increasing the weight factor of the stabilization time index of the rigid system may compensate for the differences in optimal results of the rigid–flexible coupling system.That may provide some references for optimization design of deployable space mechanisms considering clearance joints. 展开更多
关键词 clearance joint Deployable solar array Evaluation index Parameter optimization Rigid-flexible coupling dynamics
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Structural optimization of uniaxial symmetry non-circular bolt clearance hole on turbine disk 被引量:7
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作者 Chen Qiuren Guo Haiding +1 位作者 Zhang Chao Liu Xiaogang 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2014年第5期1142-1148,共7页
This study proposes a parameterized model of a uniaxial symmetry non-circular hole, to improve conventional circular bolt clearance holes on turbine disks. The profile of the model consists of eight smoothly connected... This study proposes a parameterized model of a uniaxial symmetry non-circular hole, to improve conventional circular bolt clearance holes on turbine disks. The profile of the model consists of eight smoothly connected arcs, the radiuses of which are determined by 5 design variables.By changing the design variables, the profile of the non-circular hole can be transformed to accommodate different load ratios, thereby improving the stress concentration of the area near the hole and that of the turbine disk. The uniaxial symmetry non-circular hole is optimized based on finite element method(FEM), in which the maximum first principal stress is taken as the objective function. After optimization, the stress concentration is evidently relieved; the maximum first principal stress and the maximum von Mises stress on the critical area are reduced by 30.39% and 25.34%respectively, showing that the uniaxial symmetry non-circular hole is capable of reducing the stress level of bolt clearance holes on the turbine disk. 展开更多
关键词 Bolt hole FEM Stress concentration Structural optimization Turbine disk
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Review of Metaheuristic Optimization Techniques for Enhancing E-Health Applications
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作者 Qun Song Chao Gao +3 位作者 Han Wu Zhiheng Rao Huafeng Qin Simon Fong 《Computers, Materials & Continua》 2026年第2期185-233,共49页
Metaheuristic algorithms,renowned for strong global search capabilities,are effective tools for solving complex optimization problems and show substantial potential in e-Health applications.This review provides a syst... Metaheuristic algorithms,renowned for strong global search capabilities,are effective tools for solving complex optimization problems and show substantial potential in e-Health applications.This review provides a systematic overview of recent advancements in metaheuristic algorithms and highlights their applications in e-Health.We selected representative algorithms published between 2019 and 2024,and quantified their influence using an entropy-weighted method based on journal impact factors and citation counts.CThe Harris Hawks Optimizer(HHO)demonstrated the highest early citation impact.The study also examined applications in disease prediction models,clinical decision support,and intelligent health monitoring.Notably,the Chaotic Salp Swarm Algorithm(CSSA)achieved 99.69% accuracy in detecting Novel Coronavirus Pneumonia.Future research should progress in three directions:improving theoretical reliability and performance predictability in medical contexts;designing more adaptive and deployable mechanisms for real-world systems;and integrating ethical,privacy,and technological considerations to enable precision medicine,digital twins,and intelligent medical devices. 展开更多
关键词 Metaheuristic optimization E-HEALTH disease diagnosis medical resource optimization complex optimization
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A Review of Optimization Methods for Pole-shoe Structures in Large-scale Salient Pole Synchronous Motors
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作者 Pengcheng Ma Jinxiu Chen Yiwei Ding 《CES Transactions on Electrical Machines and Systems》 2026年第1期28-43,共16页
Optimizing the rotor pole-shoe structure of large salient pole synchronous motors is critical for improving their performance and efficiency,allowing for enhanced responsiveness to grid demands and adjustments in oper... Optimizing the rotor pole-shoe structure of large salient pole synchronous motors is critical for improving their performance and efficiency,allowing for enhanced responsiveness to grid demands and adjustments in operating conditions.This paper provides a comprehensive review of various pole-shoe structures for salient pole synchronous motor rotors and their associated optimization techniques.First,it outlines the role of the pole-shoe structure and examines the theoretical theories of key electromagnetic parameters,including the pole-arc coefficient,voltage waveform coefficient,and armature reaction coefficient.Regarding structural design,this paper explores several configurations,including the threesegment arc,five-segment arc,single eccentric pole-arc combined with two chordal surface sections,and asymmetric poles.The effects of these designs on the air-gap magnetic field distribution and voltage waveform are evaluated.In terms of methodology,this paper reviews the application of numerical solutions to electromagnetic field inverse problems and the use of optimization algorithms for electrical machine structural optimization.This study illustrates the application of improved simulated annealing algorithms,tabu search algorithms,and particle swarm optimization algorithms for single-objective optimization of five-segment arc pole-shoe structures.Additionally,this paper discusses the use of vector tabu search and multi-objective quantum evolutionary algorithms for the multi-objective optimization of five-segment arc pole-shoe structures.The study concludes that multi-objective optimization algorithms are underutilized for pole-shoe structure optimization and suggests that multi-objective particle swarm optimization could be more extensively employed for this purpose.Furthermore,the potential application of topology optimization methods for the design of salient-pole synchronous motor rotor magnetic poles is proposed. 展开更多
关键词 Electromagnetic field inverse problem Fivesegment arc pole-shoe Multi-objective optimization Particle swarm optimization Rotor pole-shoe Structural optimization
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An Overall Optimization Model Using Metaheuristic Algorithms for the CNN-Based IoT Attack Detection Problem
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作者 Le Thi Hong Van Le Duc Thuan +1 位作者 Pham Van Huong Nguyen Hieu Minh 《Computers, Materials & Continua》 2026年第4期1934-1964,共31页
Optimizing convolutional neural networks(CNNs)for IoT attack detection remains a critical yet challenging task due to the need to balance multiple performance metrics beyond mere accuracy.This study proposes a unified... Optimizing convolutional neural networks(CNNs)for IoT attack detection remains a critical yet challenging task due to the need to balance multiple performance metrics beyond mere accuracy.This study proposes a unified and flexible optimization framework that leverages metaheuristic algorithms to automatically optimize CNN configurations for IoT attack detection.Unlike conventional single-objective approaches,the proposed method formulates a global multi-objective fitness function that integrates accuracy,precision,recall,and model size(speed/model complexity penalty)with adjustable weights.This design enables both single-objective and weightedsum multi-objective optimization,allowing adaptive selection of optimal CNN configurations for diverse deployment requirements.Two representativemetaheuristic algorithms,GeneticAlgorithm(GA)and Particle Swarm Optimization(PSO),are employed to optimize CNNhyperparameters and structure.At each generation/iteration,the best configuration is selected as themost balanced solution across optimization objectives,i.e.,the one achieving themaximum value of the global objective function.Experimental validation on two benchmark datasets,Edge-IIoT and CIC-IoT2023,demonstrates that the proposed GA-and PSO-based models significantly enhance detection accuracy(94.8%–98.3%)and generalization compared with manually tuned CNN configurations,while maintaining compact architectures.The results confirm that the multi-objective framework effectively balances predictive performance and computational efficiency.This work establishes a generalizable and adaptive optimization strategy for deep learning-based IoT attack detection and provides a foundation for future hybrid metaheuristic extensions in broader IoT security applications. 展开更多
关键词 Genetic algorithm(GA) particle swarm optimization(PSO) multi-objective optimization convolutional neural network—CNN IoT attack detection metaheuristic optimization CNN configuration
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Numerical simulation and optimization of clearance in sheet shearing process 被引量:1
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作者 秦泗吉 李洪波 +1 位作者 彭加耕 李硕本 《中国有色金属学会会刊:英文版》 CSCD 2003年第2期407-411,共5页
An analysis model to simplify the shearing and blanking process was developed. Based on the simplified model, the shearing process was simulated by FEM and analyzed for various clearances. An optimum clearance in the ... An analysis model to simplify the shearing and blanking process was developed. Based on the simplified model, the shearing process was simulated by FEM and analyzed for various clearances. An optimum clearance in the process was determined by new approach based on orientation of the maximum shearing stress on the characteristic line linking two blades, according to the law of crack propagation and experiments. The optimum clearance determined by this method can be used to dictate the range of reasonable clearance. By the new approach, the optimum clearance can be obtained conveniently and accurately even if there is some difference between the selected points, where the initial crack is assumed originated, and the actual one, where the initial crack occurs really. 展开更多
关键词 板材 剪切 优化 有限元 数值模拟
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MCPSFOA:Multi-Strategy Enhanced Crested Porcupine-Starfish Optimization Algorithm for Global Optimization and Engineering Design
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作者 Hao Chen Tong Xu +2 位作者 Yutian Huang Dabo Xin Changting Zhong 《Computer Modeling in Engineering & Sciences》 2026年第1期494-545,共52页
Optimization problems are prevalent in various fields of science and engineering,with several real-world applications characterized by high dimensionality and complex search landscapes.Starfish optimization algorithm(... Optimization problems are prevalent in various fields of science and engineering,with several real-world applications characterized by high dimensionality and complex search landscapes.Starfish optimization algorithm(SFOA)is a recently optimizer inspired by swarm intelligence,which is effective for numerical optimization,but it may encounter premature and local convergence for complex optimization problems.To address these challenges,this paper proposes the multi-strategy enhanced crested porcupine-starfish optimization algorithm(MCPSFOA).The core innovation of MCPSFOA lies in employing a hybrid strategy to improve SFOA,which integrates the exploratory mechanisms of SFOA with the diverse search capacity of the Crested Porcupine Optimizer(CPO).This synergy enhances MCPSFOA’s ability to navigate complex and multimodal search spaces.To further prevent premature convergence,MCPSFOA incorporates Lévy flight,leveraging its characteristic long and short jump patterns to enable large-scale exploration and escape from local optima.Subsequently,Gaussian mutation is applied for precise solution tuning,introducing controlled perturbations that enhance accuracy and mitigate the risk of insufficient exploitation.Notably,the population diversity enhancement mechanism periodically identifies and resets stagnant individuals,thereby consistently revitalizing population variety throughout the optimization process.MCPSFOA is rigorously evaluated on 24 classical benchmark functions(including high-dimensional cases),the CEC2017 suite,and the CEC2022 suite.MCPSFOA achieves superior overall performance with Friedman mean ranks of 2.208,2.310 and 2.417 on these benchmark functions,outperforming 11 state-of-the-art algorithms.Furthermore,the practical applicability of MCPSFOA is confirmed through its successful application to five engineering optimization cases,where it also yields excellent results.In conclusion,MCPSFOA is not only a highly effective and reliable optimizer for benchmark functions,but also a practical tool for solving real-world optimization problems. 展开更多
关键词 Global optimization starfish optimization algorithm crested porcupine optimizer METAHEURISTIC Gaussian mutation population diversity enhancement
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A satellite layout-structure integrated optimization method based on thermal metamaterials
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作者 Senlin HUO Bingxiao DU +2 位作者 Wei CONG Yong ZHAO Xianqi CHEN 《Chinese Journal of Aeronautics》 2026年第2期328-340,共13页
In the conceptual design phase of the satellite thermal management system,components layout optimization and structural topology optimization of satellite panel can meet global and local thermal management requirement... In the conceptual design phase of the satellite thermal management system,components layout optimization and structural topology optimization of satellite panel can meet global and local thermal management requirements,respectively.However,achieving non-interfering coupling between these two optimization processes remains a challenge.An integrated layout-structure design method based on thermal metamaterials is proposed,which comprises two design stages.In the first stage,components layout optimization is conducted to maximize temperature uniformity within the satellite module,yielding a globally optimized layout with balanced thermal characteristics.In the second stage,topology optimization guided by the design principle of thermal metamaterials is implemented in critical local panel regions to satisfy differentiated heat transfer requirements of components with diverse functional and thermal sensitivity properties.The key innovation lies in utilizing thermal metamaterials as a mediator to synergistically couple global components layout optimization with local structural topology optimization,which enables customized local heat flux manipulation without interfering with the globally optimized temperature field derived from the layout optimization.The method introduces neither additional mass nor special materials,offering advantages of low cost,high reliability,and strong versatility.It provides a new solution paradigm for the design of passive thermal management systems in satellites. 展开更多
关键词 Layout optimization METAMATERIALS SATELLITES Structure design Thermal management Topology optimization
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Multi-objective topology optimization for cutout design in deployable composite thin-walled structures
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作者 Hao JIN Ning AN +3 位作者 Qilong JIA Chun SHAO Xiaofei MA Jinxiong ZHOU 《Chinese Journal of Aeronautics》 2026年第1期674-694,共21页
Deployable Composite Thin-Walled Structures(DCTWS)are widely used in space applications due to their ability to compactly fold and self-deploy in orbit,enabled by cutouts.Cutout design is crucial for balancing structu... Deployable Composite Thin-Walled Structures(DCTWS)are widely used in space applications due to their ability to compactly fold and self-deploy in orbit,enabled by cutouts.Cutout design is crucial for balancing structural rigidity and flexibility,ensuring material integrity during large deformations,and providing adequate load-bearing capacity and stability once deployed.Most research has focused on optimizing cutout size and shape,while topology optimization offers a broader design space.However,the anisotropic properties of woven composite laminates,complex failure criteria,and multi-performance optimization needs have limited the exploration of topology optimization in this field.This work derives the sensitivities of bending stiffness,critical buckling load,and the failure index of woven composite materials with respect to element density,and formulates both single-objective and multi-objective topology optimization models using a linear weighted aggregation approach.The developed method was integrated with the commercial finite element software ABAQUS via a Python script,allowing efficient application to cutout design in various DCTWS configurations to maximize bending stiffness and critical buckling load under material failure constraints.Optimization of a classical tubular hinge resulted in improvements of 107.7%in bending stiffness and 420.5%in critical buckling load compared to level-set topology optimization results reported in the literature,validating the effectiveness of the approach.To facilitate future research and encourage the broader adoption of topology optimization techniques in DCTWS design,the source code for this work is made publicly available via a Git Hub link:https://github.com/jinhao-ok1/Topo-for-DCTWS.git. 展开更多
关键词 Composite laminates Deployable structures Multi-objective optimization Thin-walled structures Topology optimization
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A collaborative optimization design method of platform location and well trajectory for a complex-structure well factory
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作者 WANG Ge GAO Deli HUANG Wenjun 《Petroleum Exploration and Development》 2026年第1期261-271,共11页
Using platform-target matching deviation,anti-collision difficulty,trajectory complexity,and total drilling footage as objective functions,and comprehensively considering constraints such as platform layout area,drill... Using platform-target matching deviation,anti-collision difficulty,trajectory complexity,and total drilling footage as objective functions,and comprehensively considering constraints such as platform layout area,drilling extension limits,underground target distribution and trajectory collision risks,a model of platform location-wellbore trajectory collaborative optimization for a complex-structure well factory is developed.A hybrid heuristic algorithm is proposed by combining an improved sparrow search algorithm(ISSA)for optimizing platform parameters in the outer layer and a directed artificial bee colony algorithm(DABC)for optimizing trajectory parameters in the inner layer.The alternating iteration of ISSA-DABC facilitates the resolution of the collaborative optimization problem.The ISSA-DABC provides an effective solution to the platform-trajectory collaborative optimization problem for complex-structure well factories and overcomes the tendency of the traditional platform-trajectory stepwise optimization workflow to become trapped in local optima and yield inconsistent designs.The ISSA-DABC has a strong global search capability,fast convergence and good robustness,and can simultaneously satisfy multiple engineering constraints on drilling footage,trajectory complexity and collision risk,and enables automated,workflow-wide generation of constraint-compliant,near-globally optimal platform-trajectory configurations.Field applications further demonstrate that ISSA-DABC significantly reduces the objective function value and collision risk,yielding more rational platform layouts and well factory design parameters. 展开更多
关键词 complex-structure well factory ISSA DABC platform-trajectory collaborative optimization well factory parameter optimization
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PROMPTx-PE:Adaptive Optimization of Prompt Engineering Strategies for Accuracy and Robustness in Large Language Models
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作者 Talha Farooq Khan Fahad Ali +2 位作者 Majid Hussain Lal Khan Hsien-Tsung Chang 《Computers, Materials & Continua》 2026年第5期685-715,共31页
The outstanding growth in the applications of large language models(LLMs)demonstrates the significance of adaptive and efficient prompt engineering tactics.The existing methods may not be variable,vigorous and streaml... The outstanding growth in the applications of large language models(LLMs)demonstrates the significance of adaptive and efficient prompt engineering tactics.The existing methods may not be variable,vigorous and streamlined in different domains.The offered study introduces an immediate optimization outline,named PROMPTx-PE,that is going to yield a greater level of precision and strength when it comes to the assignments that are premised on LLM.The proposed systemfeatures a timely selection schemewhich is informed by reinforcement learning,a contextual layer and a dynamic weighting module which is regulated by Lyapunov-based stability guidelines.The PROMPTx-PE dynamically varies the exploration and exploitation of the prompt space,depending on real-time feedback and multi-objective reward development.Extensive testing on both benchmark(GLUE,SuperGLUE)and domain-specific data(Healthcare-QA and Industrial-NER)demonstrates a large best performance to be 89.4%and a strong robustness disconnect with under 3%computation expense.The results confirm the effectiveness,consistency,and scalability of PROMPTx-PE as a platform of adaptive prompt engineering based on recent uses of LLMs. 展开更多
关键词 Prompt engineering large language models adaptive optimization ROBUSTNESS multi-objective optimization reinforcement learning natural language processing
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Quantum-Inspired Optimization Algorithm for 3D Multi-Objective Base-Station Deployment in Next-Generation 5G/6G Wireless Network
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作者 Yao-Hsin Chou Cheng-Yen Hua +1 位作者 Ru-Wei Tseng Shu-Yu Kuo 《Computers, Materials & Continua》 2026年第5期981-996,共16页
The rapid growth of mobile and Internet of Things(IoT)applications in dense urban environments places stringent demands on future Beyond 5G(B5G)or Beyond 6G(B6G)networks,which must ensure high Quality of Service(QoS)w... The rapid growth of mobile and Internet of Things(IoT)applications in dense urban environments places stringent demands on future Beyond 5G(B5G)or Beyond 6G(B6G)networks,which must ensure high Quality of Service(QoS)while maintaining cost-efficiency and sustainable deployment.Traditional strategies struggle with complex 3D propagation,building penetration loss,and the balance between coverage and infrastructure cost.To address this challenge,this study presents the first application of a Global-best Guided Quantum-inspired Tabu Search with Quantum-Not Gate(GQTS-QNG)framework for 3D base-station deployment optimization.The problem is formulated as a multi-objective model that simultaneously maximizes coverage and minimizes deployment cost.A binary-to-decimal encodingmechanism is designed to represent discrete placement coordinates and base station types,leveraging a quantum-inspired method to efficiently search and refine solutions within challenging combinatorial environments.Global-best guidance and tabu memory are integrated to strengthen convergence stability and avoid revisiting previously explored solutions.Simulation results across user densities ranging from 1000 to 10,000 show that GQTS-QNG consistently finds deployment configurations achieving full coverage while reducing deployment cost compared with the state-of-the-art algorithms under equal iteration times.Additionally,our method generates welldistributed and structured Pareto fronts,offering diverse planning options that allow operators to flexibly balance cost and performance requirements.These findings demonstrate that GQTS-QNG is a scalable and efficient algorithm for sustainable 3D cellular network deployment in B5G/6G urban scenarios. 展开更多
关键词 3D network deployment quantum-inspired optimization B5G/6G multi-objective optimization COVERAGE deployment cost urban wireless planning
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Multi-objective ANN-driven genetic algorithm optimization of energy efficiency measures in an NZEB multi-family house building in Greece
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《建筑节能(中英文)》 2026年第2期62-62,共1页
The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measu... The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measures in a multi-family house building in Greece.The energy efficiency measures include different heating/cooling systems(such as low-temperature and high-temperature heat pumps,natural gas boilers,split units),building envelope components for floor,walls,roof and windows of variable heat transfer coefficients,the installation of solar thermal collectors and PVs.The calculations of the building loads and investment and operating and maintenance costs of the measures are based on the methodology defined in Directive 2010/31/EU,while economic assumptions are based on EN 15459-1 standard.Typically,multi-objective optimization of energy efficiency measures often requires the simulation of very large numbers of cases involving numerous possible combinations,resulting in intense computational load.The results of the study indicate that ANN-driven GA methods can be used as an alternative,valuable tool for reliably predicting the optimal measures which minimize primary energy consumption and life cycle cost of the building with greatly reduced computational requirements.Through GA methods,the computational time needed for obtaining the optimal solutions is reduced by 96.4%-96.8%. 展开更多
关键词 energy efficiency measures gas boilerssplit units building envelope components energy efficiency economic performance artificial neural network ann driven multi objective optimization economic performance optimization ANN driven GA methods
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Topology,Size,and Shape Optimization in Civil Engineering Structures:A Review
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作者 Ahmed Manguri Hogr Hassan +1 位作者 Najmadeen Saeed Robert Jankowski 《Computer Modeling in Engineering & Sciences》 2025年第2期933-971,共39页
The optimization of civil engineering structures is critical for enhancing structural performance and material efficiency in engineering applications.Structural optimization approaches seek to determine the optimal de... The optimization of civil engineering structures is critical for enhancing structural performance and material efficiency in engineering applications.Structural optimization approaches seek to determine the optimal design,by considering material performance,cost,and structural safety.The design approaches aim to reduce the built environment’s energy use and carbon emissions.This comprehensive review examines optimization techniques,including size,shape,topology,and multi-objective approaches,by integrating these methodologies.The trends and advancements that contribute to developing more efficient,cost-effective,and reliable structural designs were identified.The review also discusses emerging technologies,such as machine learning applications with different optimization techniques.Optimization of truss,frame,tensegrity,reinforced concrete,origami,pantographic,and adaptive structures are covered and discussed.Optimization techniques are explained,including metaheuristics,genetic algorithm,particle swarm,ant-colony,harmony search algorithm,and their applications with mentioned structure types.Linear and non-linear structures,including geometric and material nonlinearity,are distinguished.The role of optimization in active structures,structural design,seismic design,form-finding,and structural control is taken into account,and the most recent techniques and advancements are mentioned. 展开更多
关键词 Structural optimization topology optimization size optimization shape optimization multi-objective optimization
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Targeting the glymphatic system to promoteα-synuclein clearance:a novel therapeutic strategy for Parkinson's disease 被引量:2
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作者 Xiaoyue Lian Zhenghao Liu +6 位作者 Zuobin Gan Qingshan Yan Luyao Tong Linan Qiu Yuntao Liu Jiang-fan Chen Zhihui Li 《Neural Regeneration Research》 2026年第1期233-247,共15页
The excessive buildup of neurotoxicα-synuclein plays a pivotal role in the pathogenesis of Parkinson's disease,highlighting the urgent need for innovative therapeutic strategies to promoteα-synuclein clearance,p... The excessive buildup of neurotoxicα-synuclein plays a pivotal role in the pathogenesis of Parkinson's disease,highlighting the urgent need for innovative therapeutic strategies to promoteα-synuclein clearance,particularly given the current lack of disease-modifying treatments.The glymphatic system,a recently identified perivascular fluid transport network,is crucial for clearing neurotoxic proteins.This review aims to synthesize current knowledge on the role of the glymphatic system inα-synuclein clearance and its implications for the pathology of Parkinson's disease while emphasizing potential therapeutic strategies and areas for future research.The review begins with an overview of the glymphatic system and details its anatomical structure and physiological functions that facilitate cerebrospinal fluid circulation and waste clearance.It summarizes emerging evidence from neuroimaging and experimental studies that highlight the close correlation between the glymphatic system and clinical symptom severity in patients with Parkinson's disease,as well as the effect of glymphatic dysfunction onα-synuclein accumulation in Parkinson's disease models.Subsequently,the review summarizes the mechanisms of glymphatic system impairment in Parkinson's disease,including sleep disturbances,aquaporin-4 impairment,and mitochondrial dysfunction,all of which diminish glymphatic system efficiency.This creates a vicious cycle that exacerbatesα-synuclein accumulation and worsens Parkinson's disease.The therapeutic perspectives section outlines strategies for enhancing glymphatic activity,such as improving sleep quality and pharmacologically targeting aquaporin-4 or its subcellular localization.Promising interventions include deep brain stimulation,melatonin supplementation,γ-aminobutyric acid modulation,and non-invasive methods(such as exercise and bright-light therapy),multisensoryγstimulation,and ultrasound therapy.Moreover,identifying neuroimaging biomarkers to assess glymphatic flow as an indicator ofα-synuclein burden could refine Parkinson's disease diagnosis and track disease progression.In conclusion,the review highlights the critical role of the glymphatic system inα-synuclein clearance and its potential as a therapeutic target in Parkinson's disease.It advocates for further research to elucidate the specific mechanisms by which the glymphatic system clears misfoldedα-synuclein and the development of imaging biomarkers to monitor glymphatic activity in patients with Parkinson's disease.Findings from this review suggest that enhancing glymphatic clearance is a promising strategy for reducingα-synuclein deposits and mitigating the progression of Parkinson's disease. 展开更多
关键词 AQUAPORIN-4 ASTROCYTES cerebrospinal fluid glymphatic system interstitial fluid neurotoxic protein clearance Parkinson's disease perivascular spaces sleep disturbance Α-SYNUCLEIN
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An Adaptive Cubic Regularisation Algorithm Based on Affine Scaling Methods for Constrained Optimization
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作者 PEI Yonggang WANG Jingyi 《应用数学》 北大核心 2026年第1期258-277,共20页
In this paper,an adaptive cubic regularisation algorithm based on affine scaling methods(ARCBASM)is proposed for solving nonlinear equality constrained programming with nonnegative constraints on variables.From the op... In this paper,an adaptive cubic regularisation algorithm based on affine scaling methods(ARCBASM)is proposed for solving nonlinear equality constrained programming with nonnegative constraints on variables.From the optimality conditions of the problem,we introduce appropriate affine matrix and construct an affine scaling ARC subproblem with linearized constraints.Composite step methods and reduced Hessian methods are applied to tackle the linearized constraints.As a result,a standard unconstrained ARC subproblem is deduced and its solution can supply sufficient decrease.The fraction to the boundary rule maintains the strict feasibility(for nonnegative constraints on variables)of every iteration point.Reflection techniques are employed to prevent the iterations from approaching zero too early.Under mild assumptions,global convergence of the algorithm is analysed.Preliminary numerical results are reported. 展开更多
关键词 Constrained optimization Adaptive cubic regularisation Affine scaling Global convergence
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PID Steering Control Method of Agricultural Robot Based on Fusion of Particle Swarm Optimization and Genetic Algorithm
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作者 ZHAO Longlian ZHANG Jiachuang +2 位作者 LI Mei DONG Zhicheng LI Junhui 《农业机械学报》 北大核心 2026年第1期358-367,共10页
Aiming to solve the steering instability and hysteresis of agricultural robots in the process of movement,a fusion PID control method of particle swarm optimization(PSO)and genetic algorithm(GA)was proposed.The fusion... Aiming to solve the steering instability and hysteresis of agricultural robots in the process of movement,a fusion PID control method of particle swarm optimization(PSO)and genetic algorithm(GA)was proposed.The fusion algorithm took advantage of the fast optimization ability of PSO to optimize the population screening link of GA.The Simulink simulation results showed that the convergence of the fitness function of the fusion algorithm was accelerated,the system response adjustment time was reduced,and the overshoot was almost zero.Then the algorithm was applied to the steering test of agricultural robot in various scenes.After modeling the steering system of agricultural robot,the steering test results in the unloaded suspended state showed that the PID control based on fusion algorithm reduced the rise time,response adjustment time and overshoot of the system,and improved the response speed and stability of the system,compared with the artificial trial and error PID control and the PID control based on GA.The actual road steering test results showed that the PID control response rise time based on the fusion algorithm was the shortest,about 4.43 s.When the target pulse number was set to 100,the actual mean value in the steady-state regulation stage was about 102.9,which was the closest to the target value among the three control methods,and the overshoot was reduced at the same time.The steering test results under various scene states showed that the PID control based on the proposed fusion algorithm had good anti-interference ability,it can adapt to the changes of environment and load and improve the performance of the control system.It was effective in the steering control of agricultural robot.This method can provide a reference for the precise steering control of other robots. 展开更多
关键词 agricultural robot steering PID control particle swarm optimization algorithm genetic algorithm
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Painted Wolf Optimization:A Novel Nature-Inspired Metaheuristic Algorithm for Real-World Optimization Problems
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作者 Saeid Sheikhi 《Computers, Materials & Continua》 2026年第5期243-271,共29页
Metaheuristic optimization algorithms continue to be essential for solving complex real-world problems,yet existingmethods often struggle with balancing exploration and exploitation across diverse problem landscapes.T... Metaheuristic optimization algorithms continue to be essential for solving complex real-world problems,yet existingmethods often struggle with balancing exploration and exploitation across diverse problem landscapes.This paper proposes a novel nature-inspired metaheuristic optimization algorithm named the Painted Wolf Optimization(PWO)algorithm.The main inspiration for the PWO algorithm is the group behavior and hunting strategy of painted wolves,also known as African wild dogs in the wild,particularly their unique consensus-based voting rally mechanism,a behavior fundamentally distinct fromthe social dynamics of grey wolves.In this innovative process,pack members explore different areas to find prey;then,they hold a pre-hunting voting rally based on the alpha member to determine who will begin the hunt and attack the prey.The efficiency of the proposed PWO algorithm is evaluated by a comparison study with other well-known optimization algorithms on 33 test functions,including the Congress on Evolutionary Computation(CEC)2017 suite and different real-world engineering design cases.Furthermore,the algorithm’s performance is further tested across a spectrum of optimization problems with extensive unknown search spaces.This includes its application within the field of cybersecurity,specifically in the context of training a machine learning-based intrusion detection system(ML-IDS),achieving an accuracy of 0.90 and an F-measure of 0.9290.Statistical analyses using the Wilcoxon signed-rank test(all p<0.05)indicate that the PWO algorithm outperforms existing state-of-the-art algorithms,providing superior solutions in diverse and unpredictable optimization landscapes.This demonstrates its potential as a robust method for tackling complex optimization problems in various fields.The source code for thePWOalgorithmis publicly available at https://github.com/saeidsheikhi/Painted-Wolf-Optimization. 展开更多
关键词 optimization painted wolf optimization algorithm metaheuristic algorithm nature-inspired computing swarm intelligence
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Path planning of unmanned surface vehicles based on improved particle swarm optimization algorithm with consideration of particle sight distance
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作者 WANG Cheng YANG Junnan +3 位作者 ZHANG Xinyang QIAN Zhong ZHU Ye LIU Hong 《上海海事大学学报》 北大核心 2026年第1期9-19,共11页
To enhance the accuracy of path planning of unmanned surface vehicles(USVs),the particle swarm optimization algorithm(PSO)is improved based on species migration strategies observed in ecology.By incorporating the conc... To enhance the accuracy of path planning of unmanned surface vehicles(USVs),the particle swarm optimization algorithm(PSO)is improved based on species migration strategies observed in ecology.By incorporating the concept of particle sight distance,an improved algorithm,called SD-IPSO,is proposed for the real-time autonomous navigation of USVs in marine environments.The algorithm refines the individual behavior pattern of particles in the population,effectively improving both local and global search capabilities while avoiding premature convergence.The effectiveness of the algorithm is validated using standard test functions from CEC-2017 function library,assessing it from multiple dimensions.Sensitivity analysis is conducted on key parameters in the algorithm,including particle sight distance and population size.Results indicate that compared with PSO,SD-IPSO demonstrates significant advantages in optimization accuracy and convergence speed.The application of SD-IPSO in path planning is further investigated through a 14-point traveling salesman problem(TSP)example and navigation autonomous tests of USVs in marine environments.Findings demonstrate that the proposed algorithm exhibits superior optimization capabilities and can effectively address the path planning challenges of USVs. 展开更多
关键词 particle swarm optimization algorithm(PSO) sight distance unmanned surface vehicle(USV)
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Memristor devices for next-generation computing:from performance optimization to application-specific co-design
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作者 Zhaorui Liu Caifang Gao +5 位作者 Jingbo Yang Zuxin Chen Enlong Li Jun Li Mengjiao Li Jianhua Zhang 《International Journal of Extreme Manufacturing》 2026年第1期119-146,共28页
Memristors have emerged as a transformative technology in the realm of electronic devices,offering unique advantages such as fast switching speeds,low power consumption,and the ability to sensor-memory-compute.The app... Memristors have emerged as a transformative technology in the realm of electronic devices,offering unique advantages such as fast switching speeds,low power consumption,and the ability to sensor-memory-compute.The applications span across non-volatile memory,neuromorphic computing,hardware security,and beyond,prompting memristors to become a versatile solution for next-generation computing and data storage systems.Despite enormous potential of memristors,the transition from laboratory prototypes to large-scale applications is challenging in terms of material stability,device reproducibility,and array scalability.This review systematically explores recent advancements in high-performance memristor technologies,focusing on performance enhancement strategies through material engineering,structural design,pulse protocol optimization,and algorithm control.We provide an in-depth analysis of key performance metrics tailored to specific applications,including non-volatile memory,neuromorphic computing,and hardware security.Furthermore,we propose a co-design framework that integrates device-level optimizations with operational-level improvements,aiming to bridge the gap between theoretical models and practical implementations. 展开更多
关键词 MEMRISTOR performance optimization device design neuromorphic computing
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