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Centralized Circumcentered-Reflection Method for Solving the Convex Feasibility Problem in Sparse Signal Recovery
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作者 Chunmei LI Bangjun CHEN Xuefeng DUAN 《Journal of Mathematical Research with Applications》 2026年第1期119-133,共15页
Convex feasibility problems are widely used in image reconstruction, sparse signal recovery, and other areas. This paper is devoted to considering a class of convex feasibility problem arising from sparse signal recov... Convex feasibility problems are widely used in image reconstruction, sparse signal recovery, and other areas. This paper is devoted to considering a class of convex feasibility problem arising from sparse signal recovery. We first derive the projection formulas for a vector onto the feasible sets. The centralized circumcentered-reflection method is designed to solve the convex feasibility problem. Some numerical experiments demonstrate the feasibility and effectiveness of the proposed algorithm, showing superior performance compared to conventional alternating projection methods. 展开更多
关键词 convex feasibility problem centralized circumcentered-re ection method sparse signal recovery compressed sensing
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Feasibility of central loop TEM method for prospecting multilayer water-fi lled goaf 被引量:9
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作者 Yan Shu Xue Gou-Qiang +2 位作者 Qiu Wei-Zhong Li Hai Zhong Hua-Sen 《Applied Geophysics》 SCIE CSCD 2016年第4期587-597,736,共12页
With deep mining of coal mines, prospecting multilayer water-filled goaf has become a new content that results from geophysical exploration in coalfields. The central loop transient electromagnetic (TEM) method is f... With deep mining of coal mines, prospecting multilayer water-filled goaf has become a new content that results from geophysical exploration in coalfields. The central loop transient electromagnetic (TEM) method is favorable for prospecting conductive layers because of the coupling relationship between its field structure and formation. However, the shielding effect of conductive overburden would not only require a longer observation time when prospecting the same depth but also weaken the anomalous response of underlying layers. Through direct time domain numerical simulation and horizontal layered earth forward modeling, this paper estimates the length of observation time required to prospect the target, and the distinguishable criterion of multilayer water-filled goal is presented with observation error according to the effect of noise on observation data. The observed emf curves from Dazigou Coal Mine, Shanxi Province can distinguish multilayer water-filled goaf. In quantitative inversion interpretation of observed curves, using electric logging data as initial parameters restrains the equivalence caused by coal formation thin layers. The deduced three-layer and two-layer water-filled goals are confirmed by the drilling hole. The result suggests that when observation time is long enough and with the anomalous situation of underlying layers being greater than the observation error, the use of the central loop TEM method to orosoect a multilaver water-filled goaf is feasible. 展开更多
关键词 central loop TEM method prospecting multilayer water-filled goaf conductive shielding layer numerical and theoretical analysis length of observation time observation error distinguishable criterion
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Impact of central venous port implantation method and access choice on outcomes 被引量:2
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作者 Ayhan Erdemir Huseyin Kemal Rasa 《World Journal of Clinical Cases》 SCIE 2023年第1期116-126,共11页
BACKGROUND Although the number of patients who need central venous ports for permanent vascular access is increasing,there is still no“gold standard”for the implantation technique.AIM To identify the implantation te... BACKGROUND Although the number of patients who need central venous ports for permanent vascular access is increasing,there is still no“gold standard”for the implantation technique.AIM To identify the implantation technique that should be favored.METHODS Two hundred central venous port-implanted patients in a tertiary hospital were retrospectively evaluated.Patients were assigned into two groups according to the access method.The first group comprised patients whose jugular veins were used,and the second group comprised patients whose subclavian veins were used.Groups were evaluated regarding age,sex,application side,primary diagnosis,active follow-up period in the hospital,chemotherapy agents administered,number of complications,and the Clavien-Dindo severity score.The distribution of the variables was tested with the Kolmogorov-Smirnov test and the Mann-Whitney U test.Theχ^(2) test was used to analyze the variables.RESULTS There was no statistically significant difference between the groups regarding age,sex,side,number of chemotherapy drugs,and duration of port usage(P>0.05).Only 2 patients in group 1 had complications,whereas in group 2 we observed 19 patients with complications(P<0.05).No port occlusion was found in group 1,but the catheters of 4 patients were occluded in group 2.One port was infected in group 1 compared to three infected ports in group 2.Two port ruptures,two pneumothorax,one revision due to a mechanical problem,one tachyarrhythmia during implantation,and four suture line problems were also recorded in group 2 patients.We also showed that it would be sufficient to evaluate and wash ports once every 2 mo.CONCLUSION Our results robustly confirm that the jugular vein route is safer than the subclavian vein approach for central venous port implantation. 展开更多
关键词 Permanent vascular access central venous ports central venous port implantation methods Jugular vein route Subclavian vein approach Impact of implantation method on outcomes
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Stability and accuracy of central difference method for real-time dynamic substructure testing considering mass participation coefficient
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作者 Zheng Lichang Xu Guoshan +3 位作者 Yang Ge Wang Zhen Yang Kaibo Zheng Zhenyun 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第3期625-636,共12页
For real-time dynamic substructure testing(RTDST),the influence of the inertia force of fluid specimens on the stability and accuracy of the integration algorithms has never been investigated.Therefore,this study prop... For real-time dynamic substructure testing(RTDST),the influence of the inertia force of fluid specimens on the stability and accuracy of the integration algorithms has never been investigated.Therefore,this study proposes to investigate the stability and accuracy of the central difference method(CDM)for RTDST considering the specimen mass participation coefficient.First,the theory of the CDM for RTDST is presented.Next,the stability and accuracy of the CDM for RTDST considering the specimen mass participation coefficient are investigated.Finally,numerical simulations and experimental tests are conducted for verifying the effectiveness of the method.The study indicates that the stability of the algorithm is affected by the mass participation coefficient of the specimen,and the stability limit first increases and then decreases as the mass participation coefficient increases.In most cases,the mass participation coefficient will increase the stability limit of the algorithm,but in specific circumstances,the algorithm may lose its stability.The stability and accuracy of the CDM considering the mass participation coefficient are verified by numerical simulations and experimental tests on a three-story frame structure with a tuned liquid damper. 展开更多
关键词 real-time dynamic substructure testing central difference method STABILITY mass participation coefficient tuned liquid damper
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Assessment of Calcimetric and Titrimetric Methods for Calcium Carbonate Estimation of Five Soil Types in Central Sudan 被引量:2
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作者 Jamal T. Elfaki Mohamed O. Gafei +1 位作者 Magboul M. Sulieman Mushtaha E. Ali 《Journal of Geoscience and Environment Protection》 2016年第1期120-127,共8页
Despite the CaCO<sub>3</sub> estimation using titration method was not reliable, but up to the present time, some soil laboratories in Sudan still used this method. The objective of this study was to compa... Despite the CaCO<sub>3</sub> estimation using titration method was not reliable, but up to the present time, some soil laboratories in Sudan still used this method. The objective of this study was to compare and assess the results of calcimetric and titrimetric methods of quantitative estimation for soil calcium carbonate of different soils in Sudan. 26 soil samples from five soil profiles were collected from different climatological and ecological regions in central Sudan. CaCO<sub>3</sub> equivalent was estimated using calcimeter and titration methods in order to find accurate, rapid and suitable method for soils of Sudan. The results revealed that there are no significant differences between calcimeter and titration methods for calcium carbonate estimation in all studied samples except in samples from Gedaref area. We concluded that when the Calcimeter method used for CaCO<sub>3</sub> estimation, the differences between one person and another in detecting titration end point would be avoided, rapid and accurate results would be obtained compared to titration method. Additionally, time would be saved;fewer amounts of chemicals would be used. From this study, we highly recommend using calcimeter method for CaCO<sub>3</sub> estimation for soils of Sudan. 展开更多
关键词 Ecological Regions central Sudan Calcimeter Titration method
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Determine the Eigen Function of Schrodinger Equation with Non-Central Potential by Using NU Method
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作者 Hamdollah Salehi 《Applied Mathematics》 2011年第8期999-1004,共6页
So far, Schrodinger equation with central potential has been solved in different methods but solving this equation with non-central potentials is less dealt with. Solving such equations are way more difficult and comp... So far, Schrodinger equation with central potential has been solved in different methods but solving this equation with non-central potentials is less dealt with. Solving such equations are way more difficult and complicated and a certain and limited number of non-central potentials can be solved. In this paper, we introduce one of the solvable kinds of such potentials and we will use NU method for solving Schrodinger equation and then by using this method we have calculated particular figures of its energy and function. 展开更多
关键词 SCHRODINGER Equation(SE) Non-central POTENTIALS NU method central Potential
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Central Discontinuous Galerkin Method for the Navier-Stokes Equations
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作者 Tan Ren Chao Wang +1 位作者 Haining Dong Danjie Zhou 《Journal of Beijing Institute of Technology》 EI CAS 2017年第2期158-164,共7页
Central discontinuous Galerkin(CDG)method is used to solve the Navier-Stokes equations for viscous flow in this paper.The CDG method involves two pieces of approximate solutions defined on overlapping meshes.Taking ... Central discontinuous Galerkin(CDG)method is used to solve the Navier-Stokes equations for viscous flow in this paper.The CDG method involves two pieces of approximate solutions defined on overlapping meshes.Taking advantages of the redundant representation of the solution on the overlapping meshes,the cell interface of one computational mesh is right inside the staggered mesh,hence approximate Riemann solvers are not needed at cell interfaces.Third order total variation diminishing(TVD)Runge-Kutta(RK)methods are applied in time discretization.Numerical examples for 1D and2 D viscous flow simulations are presented to validate the accuracy and robustness of the CDG method. 展开更多
关键词 central discontinuous Galerkin (CDG) method Navier-Stokes equations total variationdiminishing TVD Runge-Kutta (RK) methods
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Extraction Process Optimization of Total Flavonoids from Mallotus apelta Stems by Central Composite Design/Response Surface Method 被引量:2
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作者 Xiao HUANG Dengfeng ZOU +3 位作者 Ruifen FAN Shuoying GUO Hua ZHU Aize XIE 《Medicinal Plant》 2017年第5期54-57,共4页
[Objectives] To optimize the extraction process of total flavonoids in stems of Mallotus apelta. [Methods]On the basis of singlefactor test,with volume fraction of ethanol,extraction time and ratio of solvent as indep... [Objectives] To optimize the extraction process of total flavonoids in stems of Mallotus apelta. [Methods]On the basis of singlefactor test,with volume fraction of ethanol,extraction time and ratio of solvent as independent variables,the content of total flavonoids as dependent variables,the completely secondary response surface regression fitting was conducted on the independent and dependent variables,and the Response Surface Method was used to optimize the optimum extraction process of total flavonoids in Mallotus apelta stems and predict the optimum process. [Results] The optimum extraction process of total flavonoids in Mallotus apelta was determined as follows: ethanol concentration of 71. 5%; extraction time of 154. 6 min; solid-liquid ratio of 1∶19. 2; total flavonoids content of 7. 060 mg/g; fitted binomial squared correlation coefficient R^2= 0. 8751.[Conclusions]Composite Design/Response Surface Method could be used in the extraction process optimization of total flavonoids in Mallotus apelta stems,the mathematical model established had high prediction accuracy,the method was simple and operability was good. 展开更多
关键词 central COMPOSITE Design/Response Surface method Mallotus apelta TOTAL FLAVONOIDS
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Analysis of Present Situation and Influencing Factors of Coping Methods by Parents of Children with Central Nervous System Tumors
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作者 Lan Bai Qinqin Zhao +1 位作者 Chunju Xiao Zhihuan Zhou 《World Journal of Neuroscience》 2020年第4期206-215,共10页
<b>Background:</b></span></b></span><span><span><span style="font-family:""> Central nervous system (CNS) tumors are the most common solid tumors among ch... <b>Background:</b></span></b></span><span><span><span style="font-family:""> Central nervous system (CNS) tumors are the most common solid tumors among children. Due to the severity of the tumors and the complexity of therapeutic regimes, it is very important to examine whether parents of the children with CNS tumors have positive coping methods against the disease. This study aims to analyze the coping methods of the parents and the factors influencing the methods. <b>Methods:</b> A total of 108 parents of brain cancer children admitted from January 2019 to September 2020 were selected as subjects. After collecting the general information of the parents, they were studied using the Coping Health Inventory for Parents (CHIP, Chinese ver<span>sion). Additionally, their coping pattern and the influencing factors were</span> analyzed. <b>Results:</b> The average scores of the three subscales of the CHIP were (4.25 ± 0.939), (3.11 ± 1.205) and (3.60 ± 1.187), respectively. Univariate analysis showed that parents’ education, medical payment methods, places of residence and economic concerns were the main factors influencing the coping methods (all <i>P</i> < 0.05). <b>Conclusions:</b> Healthcare staff should fully evaluate the coping methods adopted by the parents having children with CNS tumors, take targeted nursing measures accordingly, and assist the parents in seeking social support and learning disease-related knowledge. In addition, public education on disease is equally important.</span></span></span><span style="font-family:""></span> </p> 展开更多
关键词 Coping methods PARENTS CHILDREN central Nervous System Tumors
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Research and Application of Verticality Detection Method for Circular Pier with Equal Section
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作者 Zhenbang Lu Yuting Cheng +3 位作者 Lisheng Zhao Shi’ao Shi Ming Kou Zihao Peng 《Journal of World Architecture》 2025年第2期55-60,共6页
This article presents four techniques for assessing verticality:the plumb line approach,the total station distance technique,the three-point centering method,and the centroid method.Given the significant error associa... This article presents four techniques for assessing verticality:the plumb line approach,the total station distance technique,the three-point centering method,and the centroid method.Given the significant error associated with the total station horizontal distance technique when measuring circular piers,this paper proposes the centroid method.This method calculates verticality by determining the coordinates of the center points at both ends of the pier.Experimental findings indicate that the centroid method achieves accuracy in measuring the verticality of circular piers comparable to the three-point centering method,while offering a faster inspection process.Furthermore,the paper explores the concept of composite verticality and validates the effectiveness of the centroid method in measuring composite verticality and its practical applications through comparative experiments. 展开更多
关键词 VERTICALITY centrality method Synthetic verticality
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Centralized Solar PV Systems for Static Loads Using Constant Voltage Control Method
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作者 S. Alagammal N. Rathina Prabha I. Aarthy 《Circuits and Systems》 2016年第13期4213-4226,共14页
The alternative energy resources, like solar, are always complementary due to environmental changes. Energy generation with the sources such as solar and wind is gaining importance and of that photovoltaic conversion ... The alternative energy resources, like solar, are always complementary due to environmental changes. Energy generation with the sources such as solar and wind is gaining importance and of that photovoltaic conversion is the main focus of researches due to its promising potential as the electrical source. This paper presents the constant voltage method of control where the output of the converter is maintained constant irrespective of the variations in the irradiance with the high step-up isolated efficient single switch DC-DC converter for the solar PV systems. Constant voltage method of control uses the array of photovoltaic systems as its energy source. The output of the Solar PV systems is nonlinear and has its dependency on temperature and irradiance by which the panel voltage and current varies with the variation in irradiance. Constant voltage control method always operates in such a way that the converter voltage is tried to be maintained constantly to the reference voltage which is set by the user. The system used here utilizes high step single switch isolated DC-DC converter and monitors the voltage continuously by varying the duty cycle to maintain the converter voltage always constant. As a way of improving the performance, both the open and closed loop analysis is done where the closed loop analysis uses the PI controller for its performance. The model is implemented in MATLAB and it accepts the irradiance as the input and outputs the constant voltage from the converter and the feasibility of the proposed converter topology is confirmed with experimental results of the prototype model. 展开更多
关键词 Photovoltaic System centralized System Constant Voltage Control method Proportional-Integral Controller
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基于载荷控制的大曲率井抽油杆扶正器布点设计
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作者 吕凤霞 张胜 +3 位作者 束雨 唐明 韩赛越 徐瑞辰 《石油机械》 北大核心 2026年第1期102-109,共8页
加装扶正器可有效缓解大曲率井杆管柱间的偏磨问题,然而扶正器的布置数量过多会导致抽油杆下行阻力增大,降低采油效率。为此,采用有限单元法建立大曲率井杆管接触有限元分析模型,对大曲率井不同扶正器布置方案进行计算;以扶正器、杆体... 加装扶正器可有效缓解大曲率井杆管柱间的偏磨问题,然而扶正器的布置数量过多会导致抽油杆下行阻力增大,降低采油效率。为此,采用有限单元法建立大曲率井杆管接触有限元分析模型,对大曲率井不同扶正器布置方案进行计算;以扶正器、杆体、接箍与油管的接触载荷作为约束条件,以减少扶正器布置数量作为目标,采用搜索迭代法对扶正器数量进行优化布置,并开展现场实例分析。分析结果表明:随着井斜角及全角变化率的改变,每根抽油杆上布置不同数量的扶正器即可有效隔离杆体、接箍与油管的接触,且控制其接触载荷在许用载荷范围内;与优化前布置78个扶正器相比,优化后扶正器数量减少了23个,大幅减少了扶正器用量。研究结果可为油田实际生产提供指导作用。 展开更多
关键词 大曲率井 有限元法 接触载荷 扶正器 布点优化 接触载荷 搜索迭代法
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数字普惠金融对我国中部地区乡村产业振兴的影响
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作者 兰国辉 黄娟 《沈阳大学学报(社会科学版)》 2026年第1期37-48,共12页
基于2013—2022年我国中部地区6个省份的面板数据,构建乡村产业振兴水平评价指标体系,运用固定效应模型和门槛效应模型进行实证检验,分析数字普惠金融对乡村产业振兴的影响效果与门槛效应。研究结果表明:数字普惠金融对中部地区乡村产... 基于2013—2022年我国中部地区6个省份的面板数据,构建乡村产业振兴水平评价指标体系,运用固定效应模型和门槛效应模型进行实证检验,分析数字普惠金融对乡村产业振兴的影响效果与门槛效应。研究结果表明:数字普惠金融对中部地区乡村产业振兴发展产生良好的积极影响;数字普惠金融所发挥的影响作用也展现出显著的差异化特征,结合地域特点展开数字普惠金融建设显得尤为重要。研究结果进一步表明,数字普惠金融对中部地区乡村产业振兴水平的提升作用表现出单一门槛效应,二者之间具有一定的非线性递增关系。提出了推进金融服务“线上化”、搭建数字化农业服务平台,因地制宜制定差异化数字普惠金融政策,完善乡村征信系统、加强乡村金融监管力度等建议。 展开更多
关键词 数字普惠金融 乡村产业振兴 中部地区 熵值法 门槛效应
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曲普瑞林治疗中枢性性早熟不良事件信号的挖掘与分析:基于FAERS数据库的真实世界研究
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作者 李颖 张秋丽 +2 位作者 李杰 常贺生 庄太凤 《生殖医学杂志》 2026年第1期80-86,共7页
目的挖掘曲普瑞林治疗中枢性性早熟(CPP)的药品不良事件(AE),以促进临床安全用药。方法收集2004年第1季度至2024年第3季度美国FDA不良事件报告系统(FAERS)所有曲普瑞林治疗CPP的AE报告,运用国际医学用语词典中的系统器官分类(SOC)和首选... 目的挖掘曲普瑞林治疗中枢性性早熟(CPP)的药品不良事件(AE),以促进临床安全用药。方法收集2004年第1季度至2024年第3季度美国FDA不良事件报告系统(FAERS)所有曲普瑞林治疗CPP的AE报告,运用国际医学用语词典中的系统器官分类(SOC)和首选语(PT)进行分析,采用报告比值比法和综合标准法进行数据挖掘。结果曲普瑞林治疗CPP的AE报告500例次,涉及患者168人。检测到AE阳性信号22个,其中新发现7个(脑肿瘤、阑尾炎、步态无力、生长迟缓、多汗、虚弱和自杀想法)。AE报告中,61.90%的病例为重症报告,21.43%的病例需要住院治疗。另外,既往研究中腹痛、痤疮、视力障碍、鼻出血、呕吐、恶心、便秘、高血压、血催乳素升高等AE在该研究中未检测到阳性信号。结论儿童应用曲普瑞林治疗CPP的AE总体罕见,但报告的AE部分较重,应注意新发现的AE,对于非阳性信号的AE应鉴别其原因。 展开更多
关键词 曲普瑞林 中枢性性早熟 药品不良事件 FAERS数据库 报告比值比法 综合标准法
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延期起爆条件下爆破振动加速度的传播与衰减特性
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作者 张祚富 徐振洋 +2 位作者 魏熙来 任富强 陈占扬 《爆破器材》 北大核心 2026年第1期55-64,共10页
为了解延期爆破条件下振动加速度的传播与衰减特性,通过理论分析和仿真信号试验,验证了中心差分法的计算精度与误差影响因素,并将现场实测爆破振速信号转换为振动加速度信号。利用多次现场爆破振动监测数据,对不同延期时间下,爆破振速... 为了解延期爆破条件下振动加速度的传播与衰减特性,通过理论分析和仿真信号试验,验证了中心差分法的计算精度与误差影响因素,并将现场实测爆破振速信号转换为振动加速度信号。利用多次现场爆破振动监测数据,对不同延期时间下,爆破振速与加速度振幅、主频、平均频率及加速度振级的传播及衰减特性进行了研究。结果表明:加速度在爆破近区与远区的衰减存在着较为显著的差异,振动近区衰减速率高于远区;延期时间对振速与加速度振幅的影响较大,而对衰减速率的影响较小,不同延期时间下振速和加速度的衰减速率几乎相同;随着距离的增加,频率呈现出先快速下降、后缓慢下降的趋势,相较于主频,平均频率衰减更具规律性。 展开更多
关键词 爆破振动 中心差分法 振动加速度 衰减特性 环境效应
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金融机构风险的传染路径与时变特征——基于修正MES方法的实证研究
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作者 梁义娟 李洁 巴红静 《当代金融研究》 2026年第1期1-16,共16页
基于2008-2025年中国34家上市金融机构股票收益率数据,运用修正MES与DMST方法构建动态风险传染网络,考察金融风险传染路径及时变特征。研究发现:(1)金融机构的尾部风险具有顺周期性,受风险事件冲击骤升;(2)银行、证券及保险行业内关联较... 基于2008-2025年中国34家上市金融机构股票收益率数据,运用修正MES与DMST方法构建动态风险传染网络,考察金融风险传染路径及时变特征。研究发现:(1)金融机构的尾部风险具有顺周期性,受风险事件冲击骤升;(2)银行、证券及保险行业内关联较强,多元金融多与证券跨行业关联;(3)风险驱动与承担主体由银行转向证券;(4)银行和证券长期是重要传染桥梁,部分中小规模但关联密切的机构成为关键传播节点。研究结论可为监管部门评估金融机构风险重要性、完善系统重要性机构名单及实施动态风险监管提供经验证据。 展开更多
关键词 金融风险 风险传染 MES方法 网络中心度
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基于Taguchi试验的CCD响应面法精确设计气辅成型参数
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作者 孙祖东 任清海 耿铁 《合成树脂及塑料》 北大核心 2026年第1期55-59,共5页
以典型气辅塑件的气体穿透深度和最大气指缺陷为成型质量控制目标,运用Moldflow API/3DGAS气辅成型数值模拟并结合Taguchi试验优化气辅成型时间,采用极差分析研究气辅成型时间对气体穿透深度和最大气指缺陷的影响规律,并用多目标综合平... 以典型气辅塑件的气体穿透深度和最大气指缺陷为成型质量控制目标,运用Moldflow API/3DGAS气辅成型数值模拟并结合Taguchi试验优化气辅成型时间,采用极差分析研究气辅成型时间对气体穿透深度和最大气指缺陷的影响规律,并用多目标综合平衡法获得优化参数:气体注射时间10.00 s,气体延迟时间4.00 s,气体保压时间20.00 s。采用中心复合试验设计响应面法对优化参数进行精确设计,获得气体注射时间和气体延迟时间的精准值分别为10.37,4.00 s。通过实际气辅成型实验验证,塑件的气体穿透深度和最大气指缺陷合理,并具有良好的表面质量。 展开更多
关键词 气辅成型 Taguchi试验 中心复合试验设计响应面法 气体穿透深度 气指缺陷
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深化“三教”改革背景下的中职数学教学优化策略探析
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作者 庄艺增 《成才之路》 2026年第5期73-76,共4页
“三教”改革,即教师、教材、教法改革。“三教”改革背景下优化中职数学教学,有助于激发学生的数学学习兴趣、提高学生的职业竞争力以及创新与表达能力,有助于提高教师的综合教学能力。文章基于中心性、职业性、素养性原则,探究“三教... “三教”改革,即教师、教材、教法改革。“三教”改革背景下优化中职数学教学,有助于激发学生的数学学习兴趣、提高学生的职业竞争力以及创新与表达能力,有助于提高教师的综合教学能力。文章基于中心性、职业性、素养性原则,探究“三教”改革背景下的中职数学教学优化策略,即狠抓教师以转变教学理念,狠抓教材以优化教学内容,狠抓教法以提高学生的知识应用能力,优化评价以形成良性循环,以此提高中职数学教学效果以及学生应用数学知识解决实际问题的能力。 展开更多
关键词 中职数学 “三教”改革 中心性 职业性 素养性 教材 教法
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基于脑电信号探究“短刺法”治疗膝骨关节炎的中枢作用机制
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作者 任毅 吴会英 +2 位作者 李维科 曾奇 刘艳玲 《中国针灸》 北大核心 2026年第1期29-38,共10页
目的:基于脑电信号(EEG)探究“短刺法”治疗膝骨关节炎(KOA)的中枢作用机制。方法:招募KOA患者31例作为KOA组,纳入年龄、性别及体质量指数(BMI)相匹配的健康受试者31例作为健康组。KOA组予“短刺法”治疗,穴取患侧内膝眼、犊鼻、阴陵泉... 目的:基于脑电信号(EEG)探究“短刺法”治疗膝骨关节炎(KOA)的中枢作用机制。方法:招募KOA患者31例作为KOA组,纳入年龄、性别及体质量指数(BMI)相匹配的健康受试者31例作为健康组。KOA组予“短刺法”治疗,穴取患侧内膝眼、犊鼻、阴陵泉、足三里和梁丘,每天1次,连续治疗6 d为一疗程,疗程间休息1 d,共治疗4个疗程。分别于治疗前后观察KOA组患者西安大略和麦克马斯特大学骨关节炎指数量表(WOMAC)评分,检测关节滑液炎症因子[白细胞介素-1β(IL-1β)和肿瘤坏死因子-α(TNF-α)]含量;分析KOA患者治疗前后及健康组受试者静息态EEG(Delta、Theta、Alpha、Beta、Gamma频段)相对功率及脑电网络拓扑指标(全局聚类系数、全局有效率、平均度、网络密度)。结果:①KOA组患者WOMAC关节疼痛指数、僵硬指数、功能活动指数评分及总分均较治疗前降低(P<0.001);关节滑液IL-1β和TNF-α含量均较治疗前降低(P<0.001)。②在Theta频段上,治疗后,KOA组患者10个脑区相对功率较治疗前降低(P<0.05,P<0.01);治疗前,除前额叶区外,KOA组患者其他脑区相对功率较健康组升高(P<0.01)。在Beta频段上,治疗后,除前额叶外,KOA组患者其他脑区相对功率较治疗前升高(P<0.05,P<0.01);治疗前,KOA组患者左额叶区、右额叶区、左顶叶区、右顶叶区、中央顶叶区、左颞叶区、右颞叶区及枕叶区相对功率低于健康组(P<0.01)。③与健康组比较,KOA组患者治疗前额叶区Theta频段和Gamma频段对应的脑功能连接网络异常增强;治疗后,其脑网络的异常连接强度减弱。(4)治疗后,KOA组患者额叶区Theta频段和Gamma频段脑网络的全局聚类系数、平均度及全局有效率均较治疗前降低(P<0.05),趋近于健康组(P>0.05);治疗前,KOA组患者额叶区Theta频段脑网络的4个拓扑指标均高于健康组(P<0.01)。(5)KOA组患者左额叶区Theta频段相对功率与WOMAC评分治疗前后差值呈正相关(P<0.05);右额叶区Gamma频段相对功率与WOMAC评分治疗前后差值呈负相关(P<0.05)。结论:“短刺法”可有效改善KOA患者关节功能,降低慢波Theta波、增加快波Beta波,调控异常增强的脑功能连接网络,这种改变与WOMAC评分具有相关性。 展开更多
关键词 膝骨关节炎 短刺法 神经电生理 脑电信号 中枢机制
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O/W型水杨酸微乳的制备与质量评价
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作者 赵洋 王艳 +3 位作者 唐文杰 任硕晗 张桂红 李疆改 《日用化学工业(中英文)》 北大核心 2026年第2期176-184,共9页
文章通过溶解度分析、伪三元相图优化及星点设计-响应面法,制备了水杨酸微乳,并对其进行了质量评价。采用肉豆蔻酸异丙酯作为油相,吐温80与聚乙二醇400(质量比为1∶1)作为混合表面活性剂体系,优化了微乳配方。实验结果表明,最佳配方为... 文章通过溶解度分析、伪三元相图优化及星点设计-响应面法,制备了水杨酸微乳,并对其进行了质量评价。采用肉豆蔻酸异丙酯作为油相,吐温80与聚乙二醇400(质量比为1∶1)作为混合表面活性剂体系,优化了微乳配方。实验结果表明,最佳配方为油相用量5%,表面活性剂混合物用量42.7%,最大载药量达到48.303 mg/g。制备的微乳为透明澄清的O/W型液体,粒径为(7.66±0.31)nm,多分散系数为0.11±0.04,具有良好的热稳定性和冻融稳定性。体外释放实验显示,水杨酸微乳在不同介质中均具有缓释效果,48 h累积释放率接近82%~96%,显著优于游离水杨酸。酪氨酸酶抑制实验表明,水杨酸微乳显著提升了酪氨酸酶抑制效果,含量达0.5%及以上时,抑制率超过95%。研究结果表明,优化后的微乳配方具有良好的载药能力、稳定性及缓释特性,能够有效提升水杨酸的药效,可作为潜在的药物递送载体,为水杨酸的临床应用提供新的技术支持。 展开更多
关键词 水杨酸 微乳 紫外分光光度法 伪三元相图 星点设计-响应面法
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