As the most critical part of post-graduate education,the Chinese government launched Standard Resident Training in 2013 to solve the regional inequality of medical quality and meet the increasing social requirement fo...As the most critical part of post-graduate education,the Chinese government launched Standard Resident Training in 2013 to solve the regional inequality of medical quality and meet the increasing social requirement for better medical service.We integrated problem-based learning(PBL)and case-based learning(CBL)in the Endodontics Standard Resident Training.By evaluating with objective parameters including theoretical knowledge and clinical practice skill,and subjective parameters including questionnaire,it was found that PBL+CBL played a positive role in endodontic resident training with a significant difference(P<0.05).This combined training model is instructive for China’s resident training,and this result can provide a rudimentary reference to current postgraduate teaching reform.展开更多
Objective:To explore the effect of implementing the case-based three-dimensional teaching method guided by evidence-based thinking in the teaching of trainee nurses in the rehabilitation department.Method:Eighty nursi...Objective:To explore the effect of implementing the case-based three-dimensional teaching method guided by evidence-based thinking in the teaching of trainee nurses in the rehabilitation department.Method:Eighty nursing practice nurses who were conducting clinical practice learning in the Rehabilitation Department of Deyang People’s Hospital from June 2024 to May 2025 were selected as the research subjects.By using the controlled grouping method,the practice nurses from June 2024 to November 2024 were taken as the control group(n=40).The period from December 2024 to May 2025 was taken as the experimental group(n=40 students),the control group was taught by traditional teaching methods,and the experimental group was taught by evidence-based nursing combined with case teaching method.The clinical thinking ability,autonomous learning ability,exit assessment scores and teaching satisfaction of the two groups of intern nurses at the time of leaving the department were compared.Results:At the time of leaving the department,the scores of each dimension and the total score of clinical thinking ability of the intern nurses in the experimental group were higher than those in the control group(t=9.268,6.354,6.199)9.694,all p<0.05).At the time of leaving the department the scores of each dimension and the total score of the autonomous learning ability of the intern nurses in the experimental group were higher than those in the control group(t=6.998,7.333,5.503,5.977,22.244)all p<0.05).At the time of leaving the department the theoretical assessment scores and operational assessment scores of the experimental group were both higher than those of the control group(t=14.546,11.676,all p<0.05).At the time of graduation,the teaching satisfaction of the experimental group was higher than that of the control group(χ^(2)=7.314,p<0.05.Conclusion:The adoption of the case-based three-dimensional teaching.Rehabilitation method guided by the evidence-based ideology during the teaching process can effectively improve the clinical thinking ability,autonomous learning ability,departmental assessment results and teaching satisfaction of the intern nurses in the rehabilitation department,which is worthy of reference.展开更多
Aiming at the characteristics of autonomy,confrontation,and uncertainty in unmanned aerial vehicle(UAV)swarm operations,case-based reasoning(CBR)technology with advantages such as weak dependence on domain knowledge a...Aiming at the characteristics of autonomy,confrontation,and uncertainty in unmanned aerial vehicle(UAV)swarm operations,case-based reasoning(CBR)technology with advantages such as weak dependence on domain knowledge and efficient problem-solving is introduced,and a recommendation method for UAV swarm operation strategies based on CBR is proposed.Firstly,we design a universal framework for UAV swarm operation strategies from three dimensions:operation effectiveness,time,and cost.Secondly,based on the representation of operation cases,certain,fuzzy,interval,and classification attribute similarity calculation methods,as well as entropybased attribute weight allocation methods,are suggested to support the calculation of global similarity of cases.This method is utilized to match the source case with the most similarity from the historical case library,to obtain the optimal recommendation strategy for the target case.Finally,in the form of red blue confrontation,a UAV swarm operation strategy recommendation case is constructed based on actual battle cases,and a system simulation analysis is conducted.The results show that the strategy given in the example performs the best in three evaluation indicators,including cost-effectiveness,and overall outperforms other operation strategies.Therefore,the proposed method has advantages such as high real-time performance and interpretability,and can address the issue of recommending UAV swarm operation strategies in complex battlefield environments across both online and offline modes.At the same time,this study could also provide new ideas for the selection of UAV swarm operation strategies.展开更多
The combination of case-based reasoning （CBR） and genetic algorithm （GA） is considered in the problem of failure mode identification in aeronautical component failure analysis. Several imple- mentation issues such...The combination of case-based reasoning （CBR） and genetic algorithm （GA） is considered in the problem of failure mode identification in aeronautical component failure analysis. Several imple- mentation issues such as matching attributes selection, similarity measure calculation, weights learning and training evaluation policies are carefully studied. The testing applications illustrate that an accuracy of 74.67 % can be achieved with 75 balanced-distributed failure cases covering 3 failure modes, and that the resulting learning weight vector can be well applied to the other 2 failure modes, achieving 73.3 % of recognition accuracy. It is also proved that its popularizing capability is good to the recognition of even more mixed failure modes.展开更多
Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proo...Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.展开更多
In 2025,I had the honor of delivering keynote speeches at the conferences of the International Society for Diet and Activity Methods in Toronto,Canada,and the International Society of Behavioural Nutrition and Physica...In 2025,I had the honor of delivering keynote speeches at the conferences of the International Society for Diet and Activity Methods in Toronto,Canada,and the International Society of Behavioural Nutrition and Physical Activity in Auckland,Aotearoa,New Zealand.These opportunities prompted deep reflection on scientific research in general,and on physical activity and health research specifically.展开更多
Yam(Dioscorea opposita)is an important economic crop,and the development of its the cultivation tecchnology is of great significance for increasing yield,improving quality,and reducing the occurrence of pests and dise...Yam(Dioscorea opposita)is an important economic crop,and the development of its the cultivation tecchnology is of great significance for increasing yield,improving quality,and reducing the occurrence of pests and diseases.With the progression of agricultural technology and changes in market demands,the cultivation tecchnology of yam is constantly innovating and improving.This paper reviewed recent research advances in yam cultivation tecchnology,covering aspects such as soil improvement,variety selection,technological innovations,green pest control,and harvesting and storage.The goal is to provide references for the sustainable development of the yam industry.展开更多
I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single inve...I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single investigator or an isolated team.My advice is intended for early-career scientists.The product of the collaboration may be high-impact research publications,enhanced geophysical monitoring capabilities in a foreign country,or an advanced training course.Choosing the right international partner is the most important step.Keeping an open mind and being receptive to suggestions to modify the initial concept is critical.Other key steps include having a mutually agreed upon plan with achievable goals and well-defined expected outcomes.International cooperation is a richly rewarding experience that accelerates progress in the Earth Sciences.展开更多
A soft X-ray energy materials research beamline(BL20U2),a branch of energy materials beamline(E-line),has been constructed in the Shanghai Synchrotron Radiation Facility(SSRF)Phase-Ⅱ project.It is now operational for...A soft X-ray energy materials research beamline(BL20U2),a branch of energy materials beamline(E-line),has been constructed in the Shanghai Synchrotron Radiation Facility(SSRF)Phase-Ⅱ project.It is now operational for soft X-ray resonant emission spectroscopy(RXES)and soft X-ray resonant elastic scattering(REXS)investigations.Optical optimization was implemented for high performance,e.g.,photon flux,energy-resolving power,and focus spot size.RXES experiments show that the energy range extends from 150 to 1500 eV.The elastic peak measured near titanium absorption edge(@445 eV)indicates an energy resolution of the RXES spectrometer of 65 meV.The measured photon flux is 3×10^(12)photons/s at 244 eV at the RXES sample position for an SSRF electron energy of 3.5 GeV and a projected ring current as 300 mA.The spot size at the RXES sample position is 23μm in the horizontal direction and 7.9μm in the vertical direction,respectively.Moreover,the angular resolution of elastic REXS scatterometer reaches 0.005°through measurement of X-ray reflection from the single-crystal silicon wafers.A sample of the REXS scatterometer is vibrationally decoupled from its chamber and cooled using copper braids connected from an open cycle liquid helium cryo reservoir,whereas the minimum sample temperature is below 15 K.展开更多
Objective:To systematically review the current implementation status of nurses’non-pharmacological prescription authority and analyze the barriers encountered during its implementation in China,providing countermeasu...Objective:To systematically review the current implementation status of nurses’non-pharmacological prescription authority and analyze the barriers encountered during its implementation in China,providing countermeasures and references for promoting the standardized implementation of nurses’non-pharmacological prescription authority.Methods:A secondary analysis of literature was conducted to systematically search for domestic and international literature related to nurses’non-pharmacological prescription authority.Meta-analysis was performed on eligible literature to evaluate the implementation effects.Simultaneously,semi-structured in-depth interviews were conducted with healthcare workers,patients,and policymakers.Content analysis was used to organize the interview data and extract core issues and barriers.Results:A total of 46 international articles were included in the Meta-analysis,which revealed that the implementation of nurses’non-pharmacological prescription authority significantly improved patients’health management outcomes,enhanced healthcare service efficiency,and increased patient satisfaction.Conclusion:The implementation of nurses’non-pharmacological prescription authority has demonstrated significant positive effects.However,China faces multiple barriers in its advancement,necessitating efforts in optimizing policy systems,constructing collaborative models,strengthening professional skills training,and improving social awareness to guide the scientific and rational implementation of nurses’non-pharmacological prescription authority.展开更多
While conventional FISH and IHC methods struggle to decode complex tissue heterogeneity and comprehensive molecular diagnosis due to low-throughput spatial information,spatial omics technologies enable high-throughput...While conventional FISH and IHC methods struggle to decode complex tissue heterogeneity and comprehensive molecular diagnosis due to low-throughput spatial information,spatial omics technologies enable high-throughput molecular mapping across tissue microenvironments.These technologies are emerging as transformative tools in molecular diagnostics and medical research.By integrating histopathological morphology with spatial multi-omics profiling(genome,transcriptome,epigenome,and proteome),spatial omics technologies open an avenue for understanding disease progression,therapeutic resistance mechanisms,and precise diagnosis.It particularly enhances tumor microenvironment analysis by mapping immune cell distributions and functional states,which may greatly facilitate tumor molecular subtyping,prognostic assessment,and prediction of the radiotherapy and chemotherapy efficacy.Despite the substantial advancements in spatial omics,the translation of spatial omics into clinical applications remains challenging due to robustness,efficacy,clinical validation,and cost constraints.In this review,we summarize the current progress and prospects of spatial omics technologies,particularly in medical research and diagnostic applications.展开更多
Objective:To explore the application effect of flipped classroom combined with case-based learning teaching methods in pharmacoeconomics teaching.Methods:The students majoring in clinical pharmacy in 2019 were selecte...Objective:To explore the application effect of flipped classroom combined with case-based learning teaching methods in pharmacoeconomics teaching.Methods:The students majoring in clinical pharmacy in 2019 were selected as the study subjects,and the cost-effectiveness analysis of different dosage forms of Yinzhihuang in the treatment of neonatal jaundice was selected as the teaching case.The flipped classroom combined with case-based learning teaching method was used to carry out theoretical teaching to the students.After the course,questionnaires were distributed through the Sojump platform to evaluate the teaching effect.Results:The results of the questionnaire showed that 85.71%of the students believed that the flipped classroom combined with case-based learning teaching method was helpful in mobilizing the learning enthusiasm and initiative,and improving the comprehensive application ability of the knowledge of pharmacoeconomics.92.86%of the students think that it is conducive to the understanding and memorization of learning content,as well as the cultivation of teamwork,communication,etc.Conclusion:Flipped classroom combined with case-based learning teaching method can improve students’knowledge mastery,thinking skills,and practical application skills,as well as optimize and improve teachers’teaching levels.展开更多
As a vital food crop,rice is an important part of global food crops.Studying the spatiotemporal changes in rice cultivation facilitates early prediction of production risks and provides support for agricultural policy...As a vital food crop,rice is an important part of global food crops.Studying the spatiotemporal changes in rice cultivation facilitates early prediction of production risks and provides support for agricultural policy decisions related to rice.With the increasing application of satellite remote sensing technology in crop monitoring,remote sensing for rice cultivation has emerged as a novel approach,offering new perspectives for monitoring rice planting.This paper briefly outlined the current research and development status of satellite remote sensing for monitoring rice cultivation both at home and abroad.Foreign scholars have made innovations in data sources and methodologies for satellite remote sensing monitoring,and utilized multi-source satellite information and machine learning algorithms to enhance the accuracy of rice planting monitoring.Scholars in China have achieved significant results in the study of satellite remote sensing for monitoring rice cultivation.Their research and application in monitoring rice planting areas provide valuable references for agricultural production management.However,satellite remote sensing monitoring of rice still faces challenges such as low spatiotemporal resolution and difficulties related to cloud cover and data fusion,which require further in-depth investigation.Additionally,there are shortcomings in the accuracy of remote sensing monitoring for fragmented farmland plots and smallholder farming.To address these issues,future efforts should focus on developing multi-source heterogeneous data fusion analysis technologies and researching monitoring systems.These advancements are expected to enable high-precision large-scale acquisition of rice planting information,laying a foundation for future smart agriculture.展开更多
Educational cooperation,as the cornerstone and vanguard of people-to-people exchanges and practical cooperation between China and Africa,holds irreplaceable strategic significance for enhancing the quality of Africa&#...Educational cooperation,as the cornerstone and vanguard of people-to-people exchanges and practical cooperation between China and Africa,holds irreplaceable strategic significance for enhancing the quality of Africa's human capital and accelerating its structural transformation and modernization process.This paper employs“demand–supply–adaptation”as its core analytical framework and aims to systematically explore how the educational cooperation between China and Africa can serve Africa's goal of modernization more precisely and effectively.First,through reviewing and analyzing the domestic and international research literature,this paper clarifies the focus,paradigms,and shortcomings of existing research,identifying the knowledge contribution of this study.Second,utilizing detailed macro-level data,case studies,and comparative research methods,it comprehensively presents the multidimensional status,structural characteristics,and development trends of China–Africa educational cooperation in areas such as student exchanges,cooperative education,vocational and technical training,language and cultural exchange,and emerging digital education.This paper also deeply analyzes the pressing and specific demands placed on the education system by Africa's modernization development across key dimensions like economic diversification,industrialization,agricultural modernization,social governance upgrading,and digital transformation.Third,based on the cooperative principle of“Africa's needs and China's strengths,”this paper innovatively proposes systematic countermeasures and suggestions for constructing new,multi-level,high-quality,sustainable,and future-oriented pathways for China–Africa educational cooperation:(a)promoting the strategic focus of cooperation to extend from“hard infrastructure”support to empowering“soft infrastructure”;(b)deepening the integration of industry and education and school–enterprise collaboration to precisely align with Africa's industrial development needs;vigorously developing digital education and jointly building a smart education ecosystem to help Africa bridge the digital divide;(c)improving an evidence-based,third-party evaluation system for cooperative effectiveness and a full-process quality assurance system;and(d)promoting the collaborative participation of multiple actors including governments,schools,enterprises,think tanks,and social organizations to build a new cooperative pattern of coconstruction,co-governance,and shared benefits.展开更多
Nanjing’s determination to transform itself from a production base to a research center reflects China’s evolution toward higher-quality development.A refrigerator that thaws frozen meat in 10 minutes and then keeps...Nanjing’s determination to transform itself from a production base to a research center reflects China’s evolution toward higher-quality development.A refrigerator that thaws frozen meat in 10 minutes and then keeps it fresh,a cooker hood that remains clean even after 10 years without disassembling it for cleaning.展开更多
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the most prominent cause of dementia.In 2019,over 57.4million people were living with AD and other dementia subtypes,a number which is ex...Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the most prominent cause of dementia.In 2019,over 57.4million people were living with AD and other dementia subtypes,a number which is expected to increase to over 152.8 million in the next 25years.This ever-increasing burden has resulted in AD and other neurodegenerative diseases rising to one of the top 10 causes of death globally (O'Connell et al.,2024).展开更多
Taking the Changli Institute of Pomology,Hebei Academy of Agriculture and Forestry Sciences(hereinafter referred to as the Changli Institute of Pomology)as a case study,this paper explores the practical pathways throu...Taking the Changli Institute of Pomology,Hebei Academy of Agriculture and Forestry Sciences(hereinafter referred to as the Changli Institute of Pomology)as a case study,this paper explores the practical pathways through which Party building leads to the high-quality development of fruit tree research from three dimensions:theoretical convergence points,current development status,and functional mechanisms.It proposes that Party building should focus on its core roles of steering political direction,enhancing team cohesion,and upholding ethical standards.Deep integration of Party building and scientific research should be achieved through concrete platforms,with the effectiveness measured by breakthroughs in critical"bottleneck"technologies and increased income for fruit growers.The study aims to provide a practical reference for integrating Party building with professional work in the agricultural research sector.展开更多
To increase the efficiency of the multidisciplinary optimization of aircraft, an aerodynamic approximation model is improved. Based on the study of aerodynamic approximation model constructed by the scaling correction...To increase the efficiency of the multidisciplinary optimization of aircraft, an aerodynamic approximation model is improved. Based on the study of aerodynamic approximation model constructed by the scaling correction model, case-based reasoning technique is introduced to improve the approximation model for optimization. The aircraft case model is constructed by utilizing the plane parameters related to aerodynamic characteristics as attributes of cases, and the formula of case retrieving is improved. Finally, the aerodynamic approximation model for optimization is improved by reusing the correction factors of the most similar aircraft to the current one. The multidisciplinary optimization of a civil aircraft concept is carried out with the improved aerodynamic approximation model. The results demonstrate that the precision and the efficiency of the optimization can be improved by utilizing the improved aerodynamic approximation model with ease-based reasoning technique.展开更多
基金supported by the Teaching Reform Project of Stomatology College of Chongqing Medical University(KQJ202215,KQJ202204)the Teaching Reform Project of Chongqing Medical University(JY20220317).
文摘As the most critical part of post-graduate education,the Chinese government launched Standard Resident Training in 2013 to solve the regional inequality of medical quality and meet the increasing social requirement for better medical service.We integrated problem-based learning(PBL)and case-based learning(CBL)in the Endodontics Standard Resident Training.By evaluating with objective parameters including theoretical knowledge and clinical practice skill,and subjective parameters including questionnaire,it was found that PBL+CBL played a positive role in endodontic resident training with a significant difference(P<0.05).This combined training model is instructive for China’s resident training,and this result can provide a rudimentary reference to current postgraduate teaching reform.
基金2023 Higher Education Teaching Research and Reform Project of Southwest Medical University(Project No.:JG2023jdyb033)。
文摘Objective:To explore the effect of implementing the case-based three-dimensional teaching method guided by evidence-based thinking in the teaching of trainee nurses in the rehabilitation department.Method:Eighty nursing practice nurses who were conducting clinical practice learning in the Rehabilitation Department of Deyang People’s Hospital from June 2024 to May 2025 were selected as the research subjects.By using the controlled grouping method,the practice nurses from June 2024 to November 2024 were taken as the control group(n=40).The period from December 2024 to May 2025 was taken as the experimental group(n=40 students),the control group was taught by traditional teaching methods,and the experimental group was taught by evidence-based nursing combined with case teaching method.The clinical thinking ability,autonomous learning ability,exit assessment scores and teaching satisfaction of the two groups of intern nurses at the time of leaving the department were compared.Results:At the time of leaving the department,the scores of each dimension and the total score of clinical thinking ability of the intern nurses in the experimental group were higher than those in the control group(t=9.268,6.354,6.199)9.694,all p<0.05).At the time of leaving the department the scores of each dimension and the total score of the autonomous learning ability of the intern nurses in the experimental group were higher than those in the control group(t=6.998,7.333,5.503,5.977,22.244)all p<0.05).At the time of leaving the department the theoretical assessment scores and operational assessment scores of the experimental group were both higher than those of the control group(t=14.546,11.676,all p<0.05).At the time of graduation,the teaching satisfaction of the experimental group was higher than that of the control group(χ^(2)=7.314,p<0.05.Conclusion:The adoption of the case-based three-dimensional teaching.Rehabilitation method guided by the evidence-based ideology during the teaching process can effectively improve the clinical thinking ability,autonomous learning ability,departmental assessment results and teaching satisfaction of the intern nurses in the rehabilitation department,which is worthy of reference.
基金supported by the National Natural Science Foundation of China(72101263)the Natural Science Foundation of Hunan Province(2023JJ40677).
文摘Aiming at the characteristics of autonomy,confrontation,and uncertainty in unmanned aerial vehicle(UAV)swarm operations,case-based reasoning(CBR)technology with advantages such as weak dependence on domain knowledge and efficient problem-solving is introduced,and a recommendation method for UAV swarm operation strategies based on CBR is proposed.Firstly,we design a universal framework for UAV swarm operation strategies from three dimensions:operation effectiveness,time,and cost.Secondly,based on the representation of operation cases,certain,fuzzy,interval,and classification attribute similarity calculation methods,as well as entropybased attribute weight allocation methods,are suggested to support the calculation of global similarity of cases.This method is utilized to match the source case with the most similarity from the historical case library,to obtain the optimal recommendation strategy for the target case.Finally,in the form of red blue confrontation,a UAV swarm operation strategy recommendation case is constructed based on actual battle cases,and a system simulation analysis is conducted.The results show that the strategy given in the example performs the best in three evaluation indicators,including cost-effectiveness,and overall outperforms other operation strategies.Therefore,the proposed method has advantages such as high real-time performance and interpretability,and can address the issue of recommending UAV swarm operation strategies in complex battlefield environments across both online and offline modes.At the same time,this study could also provide new ideas for the selection of UAV swarm operation strategies.
文摘The combination of case-based reasoning （CBR） and genetic algorithm （GA） is considered in the problem of failure mode identification in aeronautical component failure analysis. Several imple- mentation issues such as matching attributes selection, similarity measure calculation, weights learning and training evaluation policies are carefully studied. The testing applications illustrate that an accuracy of 74.67 % can be achieved with 75 balanced-distributed failure cases covering 3 failure modes, and that the resulting learning weight vector can be well applied to the other 2 failure modes, achieving 73.3 % of recognition accuracy. It is also proved that its popularizing capability is good to the recognition of even more mixed failure modes.
文摘Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.
文摘In 2025,I had the honor of delivering keynote speeches at the conferences of the International Society for Diet and Activity Methods in Toronto,Canada,and the International Society of Behavioural Nutrition and Physical Activity in Auckland,Aotearoa,New Zealand.These opportunities prompted deep reflection on scientific research in general,and on physical activity and health research specifically.
基金Supported by Shandong Provincial Key Research and Development Program(2023TZXD034)2024 National Undergraduate Innovation Training Program(202410061062).
文摘Yam(Dioscorea opposita)is an important economic crop,and the development of its the cultivation tecchnology is of great significance for increasing yield,improving quality,and reducing the occurrence of pests and diseases.With the progression of agricultural technology and changes in market demands,the cultivation tecchnology of yam is constantly innovating and improving.This paper reviewed recent research advances in yam cultivation tecchnology,covering aspects such as soil improvement,variety selection,technological innovations,green pest control,and harvesting and storage.The goal is to provide references for the sustainable development of the yam industry.
文摘I offer suggestions to increase the probability of success of an international research project.Collaborative studies often produce more innovative and transformative scientific results than work done by a single investigator or an isolated team.My advice is intended for early-career scientists.The product of the collaboration may be high-impact research publications,enhanced geophysical monitoring capabilities in a foreign country,or an advanced training course.Choosing the right international partner is the most important step.Keeping an open mind and being receptive to suggestions to modify the initial concept is critical.Other key steps include having a mutually agreed upon plan with achievable goals and well-defined expected outcomes.International cooperation is a richly rewarding experience that accelerates progress in the Earth Sciences.
文摘A soft X-ray energy materials research beamline(BL20U2),a branch of energy materials beamline(E-line),has been constructed in the Shanghai Synchrotron Radiation Facility(SSRF)Phase-Ⅱ project.It is now operational for soft X-ray resonant emission spectroscopy(RXES)and soft X-ray resonant elastic scattering(REXS)investigations.Optical optimization was implemented for high performance,e.g.,photon flux,energy-resolving power,and focus spot size.RXES experiments show that the energy range extends from 150 to 1500 eV.The elastic peak measured near titanium absorption edge(@445 eV)indicates an energy resolution of the RXES spectrometer of 65 meV.The measured photon flux is 3×10^(12)photons/s at 244 eV at the RXES sample position for an SSRF electron energy of 3.5 GeV and a projected ring current as 300 mA.The spot size at the RXES sample position is 23μm in the horizontal direction and 7.9μm in the vertical direction,respectively.Moreover,the angular resolution of elastic REXS scatterometer reaches 0.005°through measurement of X-ray reflection from the single-crystal silicon wafers.A sample of the REXS scatterometer is vibrationally decoupled from its chamber and cooled using copper braids connected from an open cycle liquid helium cryo reservoir,whereas the minimum sample temperature is below 15 K.
基金Scientific Research Fund Project of Yunnan Provincial Department of Education(Project No.:2024J2130)。
文摘Objective:To systematically review the current implementation status of nurses’non-pharmacological prescription authority and analyze the barriers encountered during its implementation in China,providing countermeasures and references for promoting the standardized implementation of nurses’non-pharmacological prescription authority.Methods:A secondary analysis of literature was conducted to systematically search for domestic and international literature related to nurses’non-pharmacological prescription authority.Meta-analysis was performed on eligible literature to evaluate the implementation effects.Simultaneously,semi-structured in-depth interviews were conducted with healthcare workers,patients,and policymakers.Content analysis was used to organize the interview data and extract core issues and barriers.Results:A total of 46 international articles were included in the Meta-analysis,which revealed that the implementation of nurses’non-pharmacological prescription authority significantly improved patients’health management outcomes,enhanced healthcare service efficiency,and increased patient satisfaction.Conclusion:The implementation of nurses’non-pharmacological prescription authority has demonstrated significant positive effects.However,China faces multiple barriers in its advancement,necessitating efforts in optimizing policy systems,constructing collaborative models,strengthening professional skills training,and improving social awareness to guide the scientific and rational implementation of nurses’non-pharmacological prescription authority.
基金supported by the National Natural Science Foundation of China(32171022,32221005,and 32401246).
文摘While conventional FISH and IHC methods struggle to decode complex tissue heterogeneity and comprehensive molecular diagnosis due to low-throughput spatial information,spatial omics technologies enable high-throughput molecular mapping across tissue microenvironments.These technologies are emerging as transformative tools in molecular diagnostics and medical research.By integrating histopathological morphology with spatial multi-omics profiling(genome,transcriptome,epigenome,and proteome),spatial omics technologies open an avenue for understanding disease progression,therapeutic resistance mechanisms,and precise diagnosis.It particularly enhances tumor microenvironment analysis by mapping immune cell distributions and functional states,which may greatly facilitate tumor molecular subtyping,prognostic assessment,and prediction of the radiotherapy and chemotherapy efficacy.Despite the substantial advancements in spatial omics,the translation of spatial omics into clinical applications remains challenging due to robustness,efficacy,clinical validation,and cost constraints.In this review,we summarize the current progress and prospects of spatial omics technologies,particularly in medical research and diagnostic applications.
基金2022 Medical Innovation and Development Project of Lanzhou University(lzuyxcx-2022-40)2022 Education and Teaching Reform Research Project of Lanzhou University General Project(202201)The Foundation of the First Hospital of Lanzhou University(ldyyyn 2021-92)。
文摘Objective:To explore the application effect of flipped classroom combined with case-based learning teaching methods in pharmacoeconomics teaching.Methods:The students majoring in clinical pharmacy in 2019 were selected as the study subjects,and the cost-effectiveness analysis of different dosage forms of Yinzhihuang in the treatment of neonatal jaundice was selected as the teaching case.The flipped classroom combined with case-based learning teaching method was used to carry out theoretical teaching to the students.After the course,questionnaires were distributed through the Sojump platform to evaluate the teaching effect.Results:The results of the questionnaire showed that 85.71%of the students believed that the flipped classroom combined with case-based learning teaching method was helpful in mobilizing the learning enthusiasm and initiative,and improving the comprehensive application ability of the knowledge of pharmacoeconomics.92.86%of the students think that it is conducive to the understanding and memorization of learning content,as well as the cultivation of teamwork,communication,etc.Conclusion:Flipped classroom combined with case-based learning teaching method can improve students’knowledge mastery,thinking skills,and practical application skills,as well as optimize and improve teachers’teaching levels.
基金Supported by Natural Science Foundation General Project of Heilongjiang Province(C2018050).
文摘As a vital food crop,rice is an important part of global food crops.Studying the spatiotemporal changes in rice cultivation facilitates early prediction of production risks and provides support for agricultural policy decisions related to rice.With the increasing application of satellite remote sensing technology in crop monitoring,remote sensing for rice cultivation has emerged as a novel approach,offering new perspectives for monitoring rice planting.This paper briefly outlined the current research and development status of satellite remote sensing for monitoring rice cultivation both at home and abroad.Foreign scholars have made innovations in data sources and methodologies for satellite remote sensing monitoring,and utilized multi-source satellite information and machine learning algorithms to enhance the accuracy of rice planting monitoring.Scholars in China have achieved significant results in the study of satellite remote sensing for monitoring rice cultivation.Their research and application in monitoring rice planting areas provide valuable references for agricultural production management.However,satellite remote sensing monitoring of rice still faces challenges such as low spatiotemporal resolution and difficulties related to cloud cover and data fusion,which require further in-depth investigation.Additionally,there are shortcomings in the accuracy of remote sensing monitoring for fragmented farmland plots and smallholder farming.To address these issues,future efforts should focus on developing multi-source heterogeneous data fusion analysis technologies and researching monitoring systems.These advancements are expected to enable high-precision large-scale acquisition of rice planting information,laying a foundation for future smart agriculture.
文摘Educational cooperation,as the cornerstone and vanguard of people-to-people exchanges and practical cooperation between China and Africa,holds irreplaceable strategic significance for enhancing the quality of Africa's human capital and accelerating its structural transformation and modernization process.This paper employs“demand–supply–adaptation”as its core analytical framework and aims to systematically explore how the educational cooperation between China and Africa can serve Africa's goal of modernization more precisely and effectively.First,through reviewing and analyzing the domestic and international research literature,this paper clarifies the focus,paradigms,and shortcomings of existing research,identifying the knowledge contribution of this study.Second,utilizing detailed macro-level data,case studies,and comparative research methods,it comprehensively presents the multidimensional status,structural characteristics,and development trends of China–Africa educational cooperation in areas such as student exchanges,cooperative education,vocational and technical training,language and cultural exchange,and emerging digital education.This paper also deeply analyzes the pressing and specific demands placed on the education system by Africa's modernization development across key dimensions like economic diversification,industrialization,agricultural modernization,social governance upgrading,and digital transformation.Third,based on the cooperative principle of“Africa's needs and China's strengths,”this paper innovatively proposes systematic countermeasures and suggestions for constructing new,multi-level,high-quality,sustainable,and future-oriented pathways for China–Africa educational cooperation:(a)promoting the strategic focus of cooperation to extend from“hard infrastructure”support to empowering“soft infrastructure”;(b)deepening the integration of industry and education and school–enterprise collaboration to precisely align with Africa's industrial development needs;vigorously developing digital education and jointly building a smart education ecosystem to help Africa bridge the digital divide;(c)improving an evidence-based,third-party evaluation system for cooperative effectiveness and a full-process quality assurance system;and(d)promoting the collaborative participation of multiple actors including governments,schools,enterprises,think tanks,and social organizations to build a new cooperative pattern of coconstruction,co-governance,and shared benefits.
文摘Nanjing’s determination to transform itself from a production base to a research center reflects China’s evolution toward higher-quality development.A refrigerator that thaws frozen meat in 10 minutes and then keeps it fresh,a cooker hood that remains clean even after 10 years without disassembling it for cleaning.
文摘Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the most prominent cause of dementia.In 2019,over 57.4million people were living with AD and other dementia subtypes,a number which is expected to increase to over 152.8 million in the next 25years.This ever-increasing burden has resulted in AD and other neurodegenerative diseases rising to one of the top 10 causes of death globally (O'Connell et al.,2024).
基金Supported by Qinhuangdao Social Sciences Development Research Project(2025LX378).
文摘Taking the Changli Institute of Pomology,Hebei Academy of Agriculture and Forestry Sciences(hereinafter referred to as the Changli Institute of Pomology)as a case study,this paper explores the practical pathways through which Party building leads to the high-quality development of fruit tree research from three dimensions:theoretical convergence points,current development status,and functional mechanisms.It proposes that Party building should focus on its core roles of steering political direction,enhancing team cohesion,and upholding ethical standards.Deep integration of Party building and scientific research should be achieved through concrete platforms,with the effectiveness measured by breakthroughs in critical"bottleneck"technologies and increased income for fruit growers.The study aims to provide a practical reference for integrating Party building with professional work in the agricultural research sector.
文摘To increase the efficiency of the multidisciplinary optimization of aircraft, an aerodynamic approximation model is improved. Based on the study of aerodynamic approximation model constructed by the scaling correction model, case-based reasoning technique is introduced to improve the approximation model for optimization. The aircraft case model is constructed by utilizing the plane parameters related to aerodynamic characteristics as attributes of cases, and the formula of case retrieving is improved. Finally, the aerodynamic approximation model for optimization is improved by reusing the correction factors of the most similar aircraft to the current one. The multidisciplinary optimization of a civil aircraft concept is carried out with the improved aerodynamic approximation model. The results demonstrate that the precision and the efficiency of the optimization can be improved by utilizing the improved aerodynamic approximation model with ease-based reasoning technique.
