This report investigated the ordering of the alky chain of sphingomyelin （SMs） monolayers induced by cholesterol at the air/water interface using high-resolution broadband sum frequency generation vibrational spectr...This report investigated the ordering of the alky chain of sphingomyelin （SMs） monolayers induced by cholesterol at the air/water interface using high-resolution broadband sum frequency generation vibrational spectroscopy （HR-BB-SFG-VS）. The SFG spectra of the three nature sphingomyelin/cholesterol mixture monolayers with two concentrations of the cholesterol at the air/water interface are performed under different polarization combination. A new resolved CH2 symmetric stretching （d＋, ~2834 cm-1） and the CH3 symmetric stretching （r＋, ~2874 cm-1） mode are applied to characterize the conformational order in the sphingomyelin/cholesterol mixture monolayers. It was found that the cholesterol make the sphingosine backbones more conformational order. During this process, the conformational order of the N-linked acyl chain remains unaltered. Moreover, the sphingosine backbones of SMs have much larger contributions to gauche defects of SMs than one in the N-linked acyl chain. These results presented here not only shed lights on understanding of the interactions of sphingomyelin molecules with cholesterol molecules at interface but also demonstrates the ability of HR-BB-SFG to probe such complicated molecular systems.展开更多
The Fourier transform is very important to numerous applications in science and engineering. However, its usefulness is hampered by its computational expense. In this paper, in an attempt to develop a faster method fo...The Fourier transform is very important to numerous applications in science and engineering. However, its usefulness is hampered by its computational expense. In this paper, in an attempt to develop a faster method for computing Fourier transforms, the authors present parallel implementations of two new algorithms developed for the type IV Discrete Cosine Transform （DCT-IV） which support the new interleaved fast Fourier transform method. The authors discuss the realizations of their implementations using two paradigms. The first involved commodity equipment and the Message-Passing Interface （MPI） library. The second utilized the RapidMind development platform and the Cell Broadband Engine （BE） processor. These experiments indicate that the authors＇ rotation-based algorithm is preferable to their lifting-based algorithm on the platforms tested, with increased efficiency demonstrated by their MPI implementation for large data sets. Finally, the authors outline future work by discussing an architecture-oriented method for computing DCT-IVs which promises further optimization. The results indicate a promising fresh direction in the search for efficient ways to compute Fourier transforms.展开更多
基金the National Natural Science Foundation of China(No.21227802)the National Natural Science Foundation of China(Nos. 21503235, 21673251)the ICCAS for Start-up Funding
文摘This report investigated the ordering of the alky chain of sphingomyelin （SMs） monolayers induced by cholesterol at the air/water interface using high-resolution broadband sum frequency generation vibrational spectroscopy （HR-BB-SFG-VS）. The SFG spectra of the three nature sphingomyelin/cholesterol mixture monolayers with two concentrations of the cholesterol at the air/water interface are performed under different polarization combination. A new resolved CH2 symmetric stretching （d＋, ~2834 cm-1） and the CH3 symmetric stretching （r＋, ~2874 cm-1） mode are applied to characterize the conformational order in the sphingomyelin/cholesterol mixture monolayers. It was found that the cholesterol make the sphingosine backbones more conformational order. During this process, the conformational order of the N-linked acyl chain remains unaltered. Moreover, the sphingosine backbones of SMs have much larger contributions to gauche defects of SMs than one in the N-linked acyl chain. These results presented here not only shed lights on understanding of the interactions of sphingomyelin molecules with cholesterol molecules at interface but also demonstrates the ability of HR-BB-SFG to probe such complicated molecular systems.
文摘The Fourier transform is very important to numerous applications in science and engineering. However, its usefulness is hampered by its computational expense. In this paper, in an attempt to develop a faster method for computing Fourier transforms, the authors present parallel implementations of two new algorithms developed for the type IV Discrete Cosine Transform （DCT-IV） which support the new interleaved fast Fourier transform method. The authors discuss the realizations of their implementations using two paradigms. The first involved commodity equipment and the Message-Passing Interface （MPI） library. The second utilized the RapidMind development platform and the Cell Broadband Engine （BE） processor. These experiments indicate that the authors＇ rotation-based algorithm is preferable to their lifting-based algorithm on the platforms tested, with increased efficiency demonstrated by their MPI implementation for large data sets. Finally, the authors outline future work by discussing an architecture-oriented method for computing DCT-IVs which promises further optimization. The results indicate a promising fresh direction in the search for efficient ways to compute Fourier transforms.
