Vacuum treatment and ion-beam bombardment are two major processes in the low energy ion-beam implantation. To accurately study the contributions of these two major factors to the bioeffects separately, the M1 generati...Vacuum treatment and ion-beam bombardment are two major processes in the low energy ion-beam implantation. To accurately study the contributions of these two major factors to the bioeffects separately, the M1 generation variation of Arabidopsis thaliana with ion-beam implantation and vacuum treatment were compared through a series of key plant development parameters including morphological observation, biochemical assay and RAPD （random amplified polymorphic DNA） analysis. The results showed that ion-beam implantation had obvious effect on almost all of these parameters, and the vacuum treatment had some impacts on several morphological parameters such as the bolting time and the length of the primary stem. Taking the results together, the indication is that vacuum treatment has some slight contributions to the bioeffects of ion-beam implantation while ion-beam bombardment itself is the major creator of the bioeffects.展开更多
Gravity-driven membrane filtration(GDM)has increasingly captured researchers'attention due to its low energy consumption and operation&maintenance.However,severe membrane fouling and permeate DOC increase rest...Gravity-driven membrane filtration(GDM)has increasingly captured researchers'attention due to its low energy consumption and operation&maintenance.However,severe membrane fouling and permeate DOC increase restricted GDM's widespread application.This study combined granular active carbon(GAC)and magnetic particles to address this issue and results suggested that GDM3 achieved highly effective pollutant removals(85%COD_(Mn),95% UV_(254),and 65% DOC)and significant flux improvement(96%)than GDM itself.GAC pretreatment before the membrane mainly helped to reduce pollutant load and improve permeated quality while magnetic particles in situ on the membrane surface contributed to engineering more open and connected structures with less extracellular polymeric substance(EPS)and soluble microbial products(SMP)than other GDM groups due to their bioeffect.GDM3 was cost-effective and had the lowest total cost with a decrease of 7.5%and 5.7%to GDM1 and GDM2.The findings provided a deep insight into the combined GAC and magnetic particles in GDM performance improvement and played a fundamental role in developing sustainable and environmentally friendly GDM processes.展开更多
In China,rare earth elements(REE)are widely utilized in agriculture.Many studieson REE toxicology,pharmacology and biochemistry have been made both at home andabroad.However,REE damage to the functions of human memory...In China,rare earth elements(REE)are widely utilized in agriculture.Many studieson REE toxicology,pharmacology and biochemistry have been made both at home andabroad.However,REE damage to the functions of human memory,thinking andreasoning in animal experiments cannot be directly demonstrated.展开更多
The athermal bioeffects caused by nanosecond electromagnetic pulses with body cells was studied by using a broad band transverse EM-wave cell (BTEM CELL). The experimental system and preliminary mechanism analysis wer...The athermal bioeffects caused by nanosecond electromagnetic pulses with body cells was studied by using a broad band transverse EM-wave cell (BTEM CELL). The experimental system and preliminary mechanism analysis were presented.展开更多
Gravity alterations in space cause significant adaptive effects on the human body,including changes to the muscular,skeletal,and vestibular systems.However,multiple factors besides gravity exist in space;therefore,it ...Gravity alterations in space cause significant adaptive effects on the human body,including changes to the muscular,skeletal,and vestibular systems.However,multiple factors besides gravity exist in space;therefore,it is difficult to distinguish gravity-related bioeffects from those of the other factors,including radiation.Although everything on the Earth surface is subject to gravity,gravity-induced effects are not explicitly clear.Here,different research methods that have been used in gravity alterations,including parabolic flight,diamagnetic levitation,and centrifuge,are reviewed and compared.The bioeffects that are reported to be associated with altered gravity in animals are summarized,and the potential risks of hypergravity and microgravity are discussed,with a focus on microgravity,which has been studied more extensively.It should be noted that although various microgravity and hypergravity research methods have their limitations,such as the inevitable magnetic field effects in diamagnetic levitation and short duration of parabolic flight,it is evident that ground-based clinical,animal,and cellular experiments that simulate gravity alterations have served as important and necessary complements to space research.These researches not only provide critical and fundamental biological information on the effects of gravity from biomechanics and the biophysical perspectives,but also help in developing future countermeasures for astronauts.展开更多
The bioeffects of silica nanoparticles (SiNP), phosphorylate-terminated nanoparticles (PO4- NP) and amino-terminated nanoparticles (NH2NP) on HaCaT cell line have been studied in this paper. The effects of the three k...The bioeffects of silica nanoparticles (SiNP), phosphorylate-terminated nanoparticles (PO4- NP) and amino-terminated nanoparticles (NH2NP) on HaCaT cell line have been studied in this paper. The effects of the three kinds of functionalized silica nanoparticles on adherence, proliferation and cycle of HaCaT cells have been investigated. And the cel- lular uptake of the three kinds of functionalized silica nanoparticles by HaCaT cells has also been exam- ined. Results indicated that the bioeffects of the three kinds of functionalized nanoparticles on HaCaT cells were concentration-dependent. And the three kinds of functionalized nanoparticles all exhibited well bio- compatibility if the concentration was below 0.2 μg/μL. While the cytotoxicities of the three kinds of function- alized nanoparticles on HaCaT cells would increase with the increasing of nanoparticles concentration, and the following order was observed: NH2NP > SiNP > PO4NP. In addition, the quantity and rapidity of cellular uptake of nanoparticles by HaCaT cells were diverse due to the different functional groups. Under the same conditions, NH2NP was most and fast internalized by HaCaT cells, followed by SiNP, and PO4NP was the least and slowest. These results provided theoretical foundation for the safe applica- tion and further modification of silica nanoparticles, which could broaden the application of silica nano- particles in biomedicine.展开更多
基金supported by National Science Fund for Distinguished Young Scholars (No. 10225526)
文摘Vacuum treatment and ion-beam bombardment are two major processes in the low energy ion-beam implantation. To accurately study the contributions of these two major factors to the bioeffects separately, the M1 generation variation of Arabidopsis thaliana with ion-beam implantation and vacuum treatment were compared through a series of key plant development parameters including morphological observation, biochemical assay and RAPD （random amplified polymorphic DNA） analysis. The results showed that ion-beam implantation had obvious effect on almost all of these parameters, and the vacuum treatment had some impacts on several morphological parameters such as the bolting time and the length of the primary stem. Taking the results together, the indication is that vacuum treatment has some slight contributions to the bioeffects of ion-beam implantation while ion-beam bombardment itself is the major creator of the bioeffects.
基金supported by the National Key Research and Development Program of China(No.2023YFC3208002)National Natural Science Foundation of China(No.52370007)+1 种基金Excellent Youth Foundation of Hei Long Jiang Province of China(No.YQ2022E034)Anhui Provincial Key Laboratory of Environmental Pollution Control and Resource Reuse(No.2021EPC02)。
文摘Gravity-driven membrane filtration(GDM)has increasingly captured researchers'attention due to its low energy consumption and operation&maintenance.However,severe membrane fouling and permeate DOC increase restricted GDM's widespread application.This study combined granular active carbon(GAC)and magnetic particles to address this issue and results suggested that GDM3 achieved highly effective pollutant removals(85%COD_(Mn),95% UV_(254),and 65% DOC)and significant flux improvement(96%)than GDM itself.GAC pretreatment before the membrane mainly helped to reduce pollutant load and improve permeated quality while magnetic particles in situ on the membrane surface contributed to engineering more open and connected structures with less extracellular polymeric substance(EPS)and soluble microbial products(SMP)than other GDM groups due to their bioeffect.GDM3 was cost-effective and had the lowest total cost with a decrease of 7.5%and 5.7%to GDM1 and GDM2.The findings provided a deep insight into the combined GAC and magnetic particles in GDM performance improvement and played a fundamental role in developing sustainable and environmentally friendly GDM processes.
基金supported by the ResourcesEnvironmental Bureau, Chinese Academy of Sciences.
文摘In China,rare earth elements(REE)are widely utilized in agriculture.Many studieson REE toxicology,pharmacology and biochemistry have been made both at home andabroad.However,REE damage to the functions of human memory,thinking andreasoning in animal experiments cannot be directly demonstrated.
基金Project supported by the National Natural Science Foundation of China.
文摘The athermal bioeffects caused by nanosecond electromagnetic pulses with body cells was studied by using a broad band transverse EM-wave cell (BTEM CELL). The experimental system and preliminary mechanism analysis were presented.
基金Supported by the National Natural Science Foundation of China(U21A20148)Collaborative Innovation Program of Hefei Science Center CAS(2022HSC-CIP002).
文摘Gravity alterations in space cause significant adaptive effects on the human body,including changes to the muscular,skeletal,and vestibular systems.However,multiple factors besides gravity exist in space;therefore,it is difficult to distinguish gravity-related bioeffects from those of the other factors,including radiation.Although everything on the Earth surface is subject to gravity,gravity-induced effects are not explicitly clear.Here,different research methods that have been used in gravity alterations,including parabolic flight,diamagnetic levitation,and centrifuge,are reviewed and compared.The bioeffects that are reported to be associated with altered gravity in animals are summarized,and the potential risks of hypergravity and microgravity are discussed,with a focus on microgravity,which has been studied more extensively.It should be noted that although various microgravity and hypergravity research methods have their limitations,such as the inevitable magnetic field effects in diamagnetic levitation and short duration of parabolic flight,it is evident that ground-based clinical,animal,and cellular experiments that simulate gravity alterations have served as important and necessary complements to space research.These researches not only provide critical and fundamental biological information on the effects of gravity from biomechanics and the biophysical perspectives,but also help in developing future countermeasures for astronauts.
基金This work was supported by the Key Project of Natural Science Foundation of China （Grant No. 20135010）National Key Basic Research Program （Grant No. 2002CB513100-10）+2 种基金Key Technologies Research and Development Program （Grant No. 2003 BA310A16）High-Tech Research and Development （863） Program （Grant No. 2003AA302250） the National Natural Science Foundation of China （Grant No. 20405005）.
文摘The bioeffects of silica nanoparticles (SiNP), phosphorylate-terminated nanoparticles (PO4- NP) and amino-terminated nanoparticles (NH2NP) on HaCaT cell line have been studied in this paper. The effects of the three kinds of functionalized silica nanoparticles on adherence, proliferation and cycle of HaCaT cells have been investigated. And the cel- lular uptake of the three kinds of functionalized silica nanoparticles by HaCaT cells has also been exam- ined. Results indicated that the bioeffects of the three kinds of functionalized nanoparticles on HaCaT cells were concentration-dependent. And the three kinds of functionalized nanoparticles all exhibited well bio- compatibility if the concentration was below 0.2 μg/μL. While the cytotoxicities of the three kinds of function- alized nanoparticles on HaCaT cells would increase with the increasing of nanoparticles concentration, and the following order was observed: NH2NP > SiNP > PO4NP. In addition, the quantity and rapidity of cellular uptake of nanoparticles by HaCaT cells were diverse due to the different functional groups. Under the same conditions, NH2NP was most and fast internalized by HaCaT cells, followed by SiNP, and PO4NP was the least and slowest. These results provided theoretical foundation for the safe applica- tion and further modification of silica nanoparticles, which could broaden the application of silica nano- particles in biomedicine.
