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Method for Behavior Recognition of Hu Sheep in Intensive Farming Based on HLNC-YOLO
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作者 JI Ronghua CHANG Hongrui +2 位作者 ZHANG Suoxiang LIU Zhongying WU Zhonghong 《农业机械学报》 北大核心 2026年第2期265-275,共11页
Behavior recognition of Hu sheep contributes to their intensive and intelligent farming.Due to the generally high density of Hu sheep farming,severe occlusion occurs among different behaviors and even among sheep perf... Behavior recognition of Hu sheep contributes to their intensive and intelligent farming.Due to the generally high density of Hu sheep farming,severe occlusion occurs among different behaviors and even among sheep performing the same behavior,leading to missing and false detection issues in existing behavior recognition methods.A high-low frequency aggregated attention and negative sample comprehensive score loss and comprehensive score soft non-maximum suppression-YOLO(HLNC-YOLO)was proposed for identifying the behavior of Hu sheep,addressing the issues of missed and erroneous detections caused by occlusion between Hu sheep in intensive farming.Firstly,images of four typical behaviors-standing,lying,eating,and drinking-were collected from the sheep farm to construct the Hu sheep behavior dataset(HSBD).Next,to solve the occlusion issues,during the training phase,the C2F-HLAtt module was integrated,which combined high-low frequency aggregation attention,into the YOLO v8 Backbone to perceive occluded objects and introduce an auxiliary reversible branch to retain more effective features.Using comprehensive score regression loss(CSLoss)to reduce the scores of suboptimal boxes and enhance the comprehensive scores of occluded object boxes.Finally,the soft comprehensive score non-maximal suppression(Soft-CS-NMS)algorithm filtered prediction boxes during the inferencing.Testing on the HSBD,HLNC-YOLO achieved a mean average precision(mAP@50)of 87.8%,with a memory footprint of 17.4 MB.This represented an improvement of 7.1,2.2,4.6,and 11 percentage points over YOLO v8,YOLO v9,YOLO v10,and Faster R-CNN,respectively.Research indicated that the HLNC-YOLO accurately identified the behavior of Hu sheep in intensive farming and possessed generalization capabilities,providing technical support for smart farming. 展开更多
关键词 behavior recognition YOLO loss function attention mechanism
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Effect of Initial Microstructure States on Flow Behavior of Al-Zn-Mg-Cu Alloy During Hot Tensile Deformation
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作者 Wang Shuyan Zhou Yuting +3 位作者 Du Ruibo Long Shuai Lin Haitao Wang Shaoyang 《稀有金属材料与工程》 北大核心 2026年第2期302-314,共13页
To investigate the influence of Al-Zn-Mg-Cu alloy with as-homogenized and as-rolled initial microstructures on the tensile flow behavior,isothermal tensile tests were conducted on a GLEEBLE-3500 isothermal simulator a... To investigate the influence of Al-Zn-Mg-Cu alloy with as-homogenized and as-rolled initial microstructures on the tensile flow behavior,isothermal tensile tests were conducted on a GLEEBLE-3500 isothermal simulator at temperatures of 380-440℃and strain rates of 0.05-1 s^(−1).The Johnson-Cook model,Hensel-Spittel model,strain-compensated Arrhenius model,and critical fracture strain model were established.Results show that through the evaluation of the models using the correlation coefficient(R)and the average absolute relative error,the strain-compensated Arrhenius model can represent the flow behavior of the alloy more accurately.Shear bands are more pronounced in the as-homogenized specimens,whereas dynamic recrystallization is predominantly observed in as-rolled specimens.Fracture morphology analysis reveals that a mixed fracture mechanism is prevalent in the as-homogenized specimen,whereas a ductile fracture mechanism is predominant in the as-rolled specimen.The processing maps indicate that the unstable region is reduced in the as-rolled specimens compared with that in the as-homogenized specimens.The optimal hot working windows for the as-homogenized and as-rolled specimens are determined as 410-440℃/0.14-1 s^(−1)and 380-400℃/0.05-0.29 s^(−1),respectively. 展开更多
关键词 Al-Zn-Mg-Cu alloy tensile flow behavior MICROSTRUCTURE constitutive modelling processing map
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Global Existence and Blow-up of Solutions for Fourth-order Parabolic Equation with p(x)-Laplacian and Variable Exponents
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作者 YANG Chunxiao YU Lifei DUAN Chenyan 《数学进展》 北大核心 2026年第1期221-239,共19页
In this paper,we consider the fourth-order parabolic equation with p(x)Laplacian and variable exponent source ut+∆^(2)u−div(|■u|^(p(x)−2■u))=|u|^(q(x))−1u.By applying potential well method,we obtain global existence... In this paper,we consider the fourth-order parabolic equation with p(x)Laplacian and variable exponent source ut+∆^(2)u−div(|■u|^(p(x)−2■u))=|u|^(q(x))−1u.By applying potential well method,we obtain global existence,asymptotic behavior and blow-up of solutions with initial energy J(u_(0))≤d.Moreover,we estimate the upper bound of the blow-up time for J(u_(0))≤0. 展开更多
关键词 fourth-order parabolic equation variable exponent source global existence asymptotic behavior BLOW-UP
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Thermodynamics of Reduction of Titania by CH_(4)-H_(2) Gas Mixture
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作者 Tian Zhenyun Chen Jiawen +2 位作者 Zhang Run Fan Gangqiang Qiu Guibao 《稀有金属材料与工程》 北大核心 2026年第3期615-626,共12页
Given the considerable global interest in the preparation of Ti and TiC,a novel reduction method for TiO_(2) in a CH_(4)-H_(2) atmosphere was proposed,and the reduction thermodynamic behavior,phase equilibrium,and ene... Given the considerable global interest in the preparation of Ti and TiC,a novel reduction method for TiO_(2) in a CH_(4)-H_(2) atmosphere was proposed,and the reduction thermodynamic behavior,phase equilibrium,and energy consumption of TiO_(2) during its reaction with a CH_(4)-H_(2) gas mixture were investigated.The results indicate that the reaction proceeds via a stepwise reduction pathway from TiO_(2) to Ti(C,O),with the Magnéli phase(TinO_(2n-1))and Ti_(3)O_(5) serving as intermediate phases.Notably,the reduction of TiO_(2) by H_(2) is more challenging than that by CH_(4),which may be attributed to the inhibitory effect of H_(2) on the surface carbon precipitation.For the complete carbonization of 1 mol TiO_(2),the total energy required at 1000,1100,and 1200℃is 1159,925,and 977 kJ/mol,respectively,which may be related to the shift of gas-phase equilibrium and the increase in side reactions at high temperatures. 展开更多
关键词 TiO_(2) TiC_(x)O_(y) reduction-carbonization thermodynamic behavior energy consumption
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Adherence to the 24-Hour Movement Guidelines is related to a lower risk of all-cause mortality:A prospective cohort study of 14,288 participants from the SUN Project
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作者 JoséFrancisco López-Gil Mark S.Tremblay +4 位作者 Maira Bes-Rastrollo Laura Moreno-Galarraga Stefanos N.Kales MiguelÁngel Martínez-González Alejandro Fernandez-Montero 《Journal of Sport and Health Science》 2026年第3期74-83,共10页
Purpose:The purpose of this study was to examine the associations between adherence to the 24-Hour Movement Guidelines and all-cause and cause-specific mortality in a large Spanish prospective cohort.Methods:We analyz... Purpose:The purpose of this study was to examine the associations between adherence to the 24-Hour Movement Guidelines and all-cause and cause-specific mortality in a large Spanish prospective cohort.Methods:We analyzed data from 14,288 participants of the Seguimiento Universidad de Navarra(SUN)Project,followed for a mean of 12.8 years(mean baseline age=38.3 years;60.1%women).Data were collected at baseline and through biennial follow-up questionnaires(up to 10 waves,depending on year of entry).The participants self-reported 24-h movement behaviors at baseline and were categorized based on the number of guidelines met(0-3).Behaviors were assessed at baseline only;changes in adherence during follow-up were not accounted for.Cox proportional hazards models were used to estimate hazard ratios(HRs)for all-cause and cause-specific mortality,adjusting for sociodemographic,lifestyle,and clinical covariates.Results:Meeting a greater number of 24-Hour Movement Guidelines at baseline was associated with a progressively lower risk of all-cause mortality.Compared with those meeting none,the multivariable-adjusted HRs were 0.52(95%confidence interval(95%CI):0.33-0.82)for meeting 1 guideline,0.47(95%CI:0.30-0.73)for meeting 2 guidelines,and 0.44(95%CI:0.28-0.71)for meeting all 3 guidelines.Only adherence to the physical activity guidelines was independently associated with a significantly lower mortality risk(HR=0.70;95%CI:0.55-0.89).A reduced risk was also observed for cancer and other-cause mortality among those meeting 2 or more guidelines.Conclusion:Adherence to the 24-Hour Movement Guidelines at baseline,particularly physical activity,was associated with a lower risk of mortality.Promoting an integrated approach to movement behaviors may be an effective strategy for improving population health and longevity. 展开更多
关键词 Physical activity Sedentary behavior Sleep duration LIFESTYLE Movement behaviors
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Urban-rural differences in residential energy-use behavior and energy-saving awareness:Evidence from a Chinese megacity
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《建筑节能(中英文)》 2026年第2期150-150,共1页
Residential energy-use behavior and energy-saving awareness play a crucial role in sustainable urban energy planning and building energy efficiency,particularly under the pressures of climate change.However,existing s... Residential energy-use behavior and energy-saving awareness play a crucial role in sustainable urban energy planning and building energy efficiency,particularly under the pressures of climate change.However,existing studies often lack comparative analysis of urban-rural differences and tend to focus excessively on behavior patterns while neglecting the dimension of energysaving awareness.With China’s urbanization rate reaching 66.16%,understanding such regional disparities has become increasingly important.To address these research gaps,this study conducts a large-scale survey on space cooling behaviors among residents in Beijing,a representative Chinese megacity.It should be noted that living standards in such megacities are generally higher than the national average,which may shape distinctive energy-use profiles.Analyzing 1573valid samples(1064 urban/442 rural)in 2024,this study employed K-Prototypes and K-Modes clustering to identify typical cooling behavior and energy-saving awareness pattems,followed by Kendall/Chi-square correlation tests and XGBoost importance analysis to determine key influencing factors,with subsequent urban-rural comparative analysis.Results indicate that urban residents are primarily heat-sensitive or heat-tolerant,with a secondary patten of mid-low temperature preference,and generally exhibit long cooling durations;rural behavior is dominated by heat-tolerant type,followed by heat-sensitive,mid-low temperature preference,and never-on types as secondary patterns;both urban and rural areas exhibit energy-savingawareness characterized by low consumption-lowwillingness,though urban areas show marginally higher motivation;energy-saving awareness correlates with cooling behavior in rural areas,but this relationship weakens significantly in urban contexts. 展开更多
关键词 behavior patterns such regional disparities energy saving awareness residential energy use behavior climate change urban rural differences China Beijing
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A Hybrid Deep Learning Approach for Real-Time Cheating Behaviour Detection in Online Exams Using Video Captured Analysis
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作者 Dao Phuc Minh Huy Gia Nhu Nguyen Dac-Nhuong Le 《Computers, Materials & Continua》 2026年第3期1179-1198,共20页
Online examinations have become a dominant assessment mode,increasing concerns over academic integrity.To address the critical challenge of detecting cheating behaviours,this study proposes a hybrid deep learning appr... Online examinations have become a dominant assessment mode,increasing concerns over academic integrity.To address the critical challenge of detecting cheating behaviours,this study proposes a hybrid deep learning approach that combines visual detection and temporal behaviour classification.The methodology utilises object detection models—You Only Look Once(YOLOv12),Faster Region-based Convolutional Neural Network(RCNN),and Single Shot Detector(SSD)MobileNet—integrated with classification models such as Convolutional Neural Networks(CNN),Bidirectional Gated Recurrent Unit(Bi-GRU),and CNN-LSTM(Long Short-Term Memory).Two distinct datasets were used:the Online Exam Proctoring(EOP)dataset from Michigan State University and the School of Computer Science,Duy Tan Unievrsity(SCS-DTU)dataset collected in a controlled classroom setting.A diverse set of cheating behaviours,including book usage,unauthorised interaction,internet access,and mobile phone use,was categorised.Comprehensive experiments evaluated the models based on accuracy,precision,recall,training time,inference speed,and memory usage.We evaluate nine detector-classifier pairings under a unified budget and score them via a calibrated harmonic mean of detection and classification accuracies,enabling deployment-oriented selection under latency and memory constraints.Macro-Precision/Recall/F1 and Receiver Operating Characteristic-Area Under the Curve(ROC-AUC)are reported for the top configurations,revealing consistent advantages of object-centric pipelines for fine-grained cheating cues.The highest overall score is achieved by YOLOv12+CNN(97.15%accuracy),while SSD-MobileNet+CNN provides the best speed-efficiency trade-off for edge devices.This research provides valuable insights into selecting and deploying appropriate deep learning models for maintaining exam integrity under varying resource constraints. 展开更多
关键词 Online exam proctoring cheating behavior detection deep learning real-time monitoring object detection human behavior recognition
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Correction: Optimizing Exciton and Charge-Carrier Behavior in Thick-Film Organic Photovoltaics: A Comprehensive Review
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作者 Lu Wei Yaxin Yang +2 位作者 Lingling Zhan Shouchun Yin Hongzheng Chen 《Nano-Micro Letters》 2026年第1期608-608,共1页
Correction to:Nano-Micro Letters(2026)18:10.https://doi.org/10.1007/s40820-025-01852-8 Following publication of the original article[1],the authors reported that the last author’s name was inadvertently misspelled.Th... Correction to:Nano-Micro Letters(2026)18:10.https://doi.org/10.1007/s40820-025-01852-8 Following publication of the original article[1],the authors reported that the last author’s name was inadvertently misspelled.The published version showed“Hongzhen Chen”,whereas the correct spelling should be“Hongzheng Chen”.The correct author name has been provided in this Correction,and the original article[1]has been corrected. 展开更多
关键词 charge carrier behavior exciton behavior comprehensive review thick film organic photovoltaics nano micro letters
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ADCP-YOLO:A High-Precision and Lightweight Model for Violation Behavior Detection in Smart Factory Workshops
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作者 Changjun Zhou Dongfang Chen +1 位作者 Chenyang Shi Taiyong Li 《Computers, Materials & Continua》 2026年第3期1895-1919,共25页
With the rapid development of smart manufacturing,intelligent safety monitoring in industrial workshops has become increasingly important.To address the challenges of complex backgrounds,target scale variation,and exc... With the rapid development of smart manufacturing,intelligent safety monitoring in industrial workshops has become increasingly important.To address the challenges of complex backgrounds,target scale variation,and excessive model parameters in worker violation detection,this study proposes ADCP-YOLO,an enhanced lightweight model based on YOLOv8.Here,“ADCP”represents four key improvements:Alterable Kernel Convolution(AKConv),Dilated-Wise Residual(DWR)module,Channel Reconstruction Global Attention Mechanism(CRGAM),and Powerful-IoU loss.These components collaboratively enhance feature extraction,multi-scale perception,and localization accuracy while effectively reducing model complexity and computational cost.Experimental results show that ADCP-YOLO achieves a mAP of 90.6%,surpassing YOLOv8 by 3.0%with a 6.6%reduction in parameters.These findings demonstrate that ADCP-YOLO successfully balances accuracy and efficiency,offering a practical solution for intelligent safety monitoring in smart factory workshops. 展开更多
关键词 YOLO violation behavior detection AKConv CRGAM DWR Powerful-IoU
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Simultaneously improving mechanical and corrosion properties of Mg-Y-Nd-Zr alloy via Sm addition
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作者 Zheng Wu Xiaoya Chen +5 位作者 Dongzhen Wang Quanan Li Yunwei Gui Baosheng Liu Zeyu Zheng Lingxiao Wang 《Journal of Magnesium and Alloys》 2026年第1期306-323,共18页
The strength-ductility trade-off in magnesium alloys remains a critical challenge urgently requiring resolution in their engineering applications.In this study,both mechanical and corrosion properties are enhanced in ... The strength-ductility trade-off in magnesium alloys remains a critical challenge urgently requiring resolution in their engineering applications.In this study,both mechanical and corrosion properties are enhanced in extruded Mg-Y-Nd-Zr alloys by Sm addition.Sm promotes dynamic recrystallization,activates non-basal slip systems and weakens basal texture intensity,leading to the sub-grain lamellar structure and rare earth texture.The EWS2 alloy exhibits an outstanding combination of high yield strength(328 MPa)and ductility(15.1%).Furthermore,the fragmented second phases in the Sm-containing alloy are uniformly distributed,reducing the subsequent corrosion driving force after micro-galvanic corrosion and facilitating the growth of a more passivating and compact corrosion film.These combined effects contribute to the lowest degradation rate in the EWS2 alloy.This study demonstrates the correlation between microstructure and properties in Sm-containing WE series alloys,providing insights for the design of other high performance magnesium alloys. 展开更多
关键词 Mg-Y-Nd-Zr alloy Sm addition Microstructure Mechanical properties Corrosion behavior
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Long-term creep of Beishan granite under uniaxial compression
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作者 Chunping Wang Xingguang Zhao +4 位作者 Jianfeng Liu Haiyang Zhang Liang Chen Hongsu Ma Ju Wang 《International Journal of Mining Science and Technology》 2026年第1期79-93,共15页
Investigations into the long-term creep behavior of Beishan granite in uniaxial compression were conducted.Four levels of axial stress(60,70,87,and 95 MPa)were applied to rock specimens.Contrasting with earlier resear... Investigations into the long-term creep behavior of Beishan granite in uniaxial compression were conducted.Four levels of axial stress(60,70,87,and 95 MPa)were applied to rock specimens.Contrasting with earlier research,the long-term creep data in this work present a substantial advancement in the time dimension.Except for the sample subjected to 60 MPa axial loading,which did not fail after a loading duration of 1650 d,the specimens under the other three stresses all failed after sustained constant loading durations of 1204,1023,and 839 d,respectively.A lower envelope of driving stress-ratio for crystalline rocks was obtained,tending towards approximately 0.45 over an infinite time scale.According to the experimental results,as axial stress increases,both the axial strain accumulated in the transient creep process and the strain rate associated with steady-state creep deformation increase exponentially;however,the share of steady-state creep strain remains nearly constant at about82.53%.A novel damage-based creep model was put forward.It provides an enhanced depiction of the comprehensive creep process in rocks,notably improving the accuracy in forecasting the accelerated creep phase,which significantly impacts the long-term stability of engineering structures. 展开更多
关键词 Long-term strength Creep model DAMAGE Creep behavior
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Deviation Behavior Analysis and Detection Based on Flight Trajectory Data
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作者 WU Yexin ZHAO Yifei WANG Hongyong 《Transactions of Nanjing University of Aeronautics and Astronautics》 2026年第1期127-144,共18页
Flight behavior analysis provides the fundamental basis for the future development of air traffic management(ATM).The characteristics of aircraft behavior are inherently reflected in their flight trajectories,impactin... Flight behavior analysis provides the fundamental basis for the future development of air traffic management(ATM).The characteristics of aircraft behavior are inherently reflected in their flight trajectories,impacting flight efficiency and safety levels.However,existing research largely addresses inefficient or abnormal trajectories from a single perspective,with an absence of a unified evaluation standard.This paper introduces a method for analyzing flight deviation behavior based on automatic dependent surveillance-broadcast(ADS-B)data,defining novel metrics of trajectory redundancy and trajectory deviation.An adaptive detection algorithm is developed to capture diverse deviation patterns.Results reveal that higher trajectory redundancy is linked to lower operational efficiency,while trajectory deviation effectively identify stepped descents,holding patterns,detours,and other behaviors.The approach offers data-driven support for anomaly detection,performance evaluation and air traffic management,with substantial significance for civil aviation applications. 展开更多
关键词 deviation behavior flight trajectory flight safety operational efficiency DATA-DRIVEN
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Escape behavior and refuge selection preferences by two common urban birds
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作者 Haijie Zhang Yining Li +3 位作者 Yiran Wang Guofen Zhu Jiaojiao Wang Laikun Ma 《Avian Research》 2026年第1期84-94,共11页
Urbanization destroys wildlife habitats,fragmenting them into small patches with poor connectivity,leading to population declines in species sensitive to such chan ges.Escape is the most common anti-predator strategy ... Urbanization destroys wildlife habitats,fragmenting them into small patches with poor connectivity,leading to population declines in species sensitive to such chan ges.Escape is the most common anti-predator strategy adopted by birds,refuges in habitats reduce or eliminate predation risk.Therefore,creating habitats with suitable refuges for birds has significant implications for their conservation.However,there have been few studies on refuge selection in birds.This study examined the Eurasian Tree Sparrow(Passer montanus)and Oriental Magpie(Pica serica)in urban and rural areas of Chengde City,northern China by measuring their alert distance(AD),flight initiation distance(FID),an d distance fled(DF)and analyzed their refuge selection characteristics after escaping.The FID/AD ratio was employed to assess the behavioral differences of birds in the risk trade-off.The results showed that the FID and FID/AD of both species were lower in urban areas than in rural areas and were negatively correlated with immediate human density.Sparrow FID was significantly affected by group size and landing substrate type.The FID of sparrows was positively correlated with the group size.The sparrows that fled to bushes escaped earlier.In urban and rural areas,sparrows exhibited significantly lower FID,DF,and FID/AD than magpies.The species adopted different refuge selection strategies,with magpies preferentially selecting trees with greater vertical height and sparrows selecting both trees and bushes.Further analysis indicated that the horizontal and vertical distances fled of both species were lower when fleeing to bushes.Urban planning and conservation areas construction should incorporate the ecological needs of local bird species to rationally configure their habitat structure,thereby optimizing the effect of avian conservation. 展开更多
关键词 Anti-predator behavior Avian tolerance Flight initiation distance REFUGE URBANIZATION
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Optimizing strength-ductility synergy in low-Mn lightweight steel via multi-microalloying element design
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作者 Lei Liu Yue-Biao Yang +2 位作者 Xiao-Hong Chu Feng Zhou Zheng-Zhi Zhao 《Journal of Iron and Steel Research International》 2026年第1期482-499,共18页
The strength-ductility trade-off in low-Mn lightweight steels is a significant challenge due to the low thermal stability of austenite and the presence ofδ-ferrite.Two types of low-Mn lightweight steels containing V ... The strength-ductility trade-off in low-Mn lightweight steels is a significant challenge due to the low thermal stability of austenite and the presence ofδ-ferrite.Two types of low-Mn lightweight steels containing V and NbVMo microalloying elements were developed by warm rolling.Among these,NbVMo steel demonstrated superior properties,achieving a tensile strength of~1.2 GPa and a product of strength and elongation exceeding 45 GPa%.In-depth mechanism analysis by atom probe tomography and quasi-in-situ electron backscatter diffraction revealed that different microalloying compositions influence the mechanical properties by strengtheningδ-ferrite,refining retained austenite and homogenizing matrix strain.In NbVMo steel,δ-ferrite strengthening is attributed to the synergistic effects of(V,Mo,Cr,Nb)C composite precipitation,fine NbC and MoC precipitates,and the solid solution strengthening of Mo.These mechanisms collectively contribute to a higher yield strength andδ-ferrite microhardness compared to V steel.Consequently,δ-ferrite and the surrounding matrix in NbVMo steel exhibit coordinated elongation during deformation,enhancing the ductility.The improved microstructural and strain uniformity in NbVMo steel mitigates stress concentration effects onδ-ferrite deformation and serves as a barrier that delays the transformation of retained austenite.In contrast,the retained austenite in V steel exhibits a blocky morphology with larger grain sizes,resulting in lower stability.Combined with localized stress concentrations due to non-uniform strain distribution,this leads to premature transformation of retained austenite to alleviate stress,ultimately impairing elongation and the continuity of strain hardening.Furthermore,the precipitation mechanisms of(V,Mo,Cr,Nb)C composite precipitates are elucidated. 展开更多
关键词 Low-Mn lightweight steel MICROALLOYING Δ-FERRITE Retained austenite Deformation behavior
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Photobiomodulation and Addiction:Exploring Mechanisms,Therapeutic Potential,and Future Directions in Substance Use Disorders
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作者 Xiujiao Qin Hongyuan Li +1 位作者 Huiying Zhao Xiaohui Wang 《Neuroscience Bulletin》 2026年第2期471-475,共5页
Addiction,a complex and chronic neurobiological disorder,is characterized by compulsive substance use despite harmful consequences,leading to persistent alterations in brain function,particularly within the reward,mot... Addiction,a complex and chronic neurobiological disorder,is characterized by compulsive substance use despite harmful consequences,leading to persistent alterations in brain function,particularly within the reward,motivation,and decision-making systems.Despite the availability of a range of treatment options,including pharmacotherapy and behavioral therapies,relapse remains a major challenge,with many individuals struggling to maintain long-term recovery.Current treatments often show limited efficacy,underscoring the need for novel therapeutic strategies that can address the underlying neurobiological disruptions in addiction. 展开更多
关键词 PHOTOBIOMODULATION MOTIVATION behavioral therapiesrelapse therapeutic potential substance use disorders neurobiological disorder MECHANISMS ADDICTION
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Self-management and help-seeking behavior for gastroesophageal reflux symptoms:A population-based survey
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作者 Lotte J Huibertse Jasmijn Sijben +1 位作者 Yonne Peters Peter D Siersema 《World Journal of Gastroenterology》 2026年第2期124-134,共11页
BACKGROUND Despite societal guidelines recommending targeted screening for Barrett’s esophagus(BE)and esophageal adenocarcinoma(EAC)in individuals with gastroesophageal reflux symptoms(GERS),screening adherence is su... BACKGROUND Despite societal guidelines recommending targeted screening for Barrett’s esophagus(BE)and esophageal adenocarcinoma(EAC)in individuals with gastroesophageal reflux symptoms(GERS),screening adherence is suboptimal.Current screening approaches fail to identify individuals not seeking medical consultation for GERS or whose GERS are managed with‘over-the-counter’(OTC)acid suppressant therapies.AIM To assess patients’self-management and help-seeking behavior for GERS.METHODS This cross-sectional study collected data from the Dutch general population aged 18-75 years between January and April 2023 using a web-based survey.The survey included questions regarding self-management(e.g.,use of acid suppressant therapy with or without prescription)and help-seeking behavior(e.g.,consulting a primary care provider)for GERS.Simple random sampling was performed to select individuals within the target age group.In total,18156 randomly selected individuals were invited to participate.The study protocol was registered in ClinicalTrials.gov(identifier:NCT05689918).RESULTS Of the 18156 invited individuals,3214 participants(17.7%)completed the survey,of which 1572 participants(48.9%)reported GERS.Of these,904 participants(57.5%)had never consulted a primary care provider for these symptoms,of which 331 participants(36.6%)reported taking OTC acid suppressant therapy in the past six months and 100 participants(11.1%)fulfilled the screening criteria for BE and EAC according to the European Society of Gastrointestinal Endoscopy Guideline.CONCLUSION The population fulfilling the screening criteria for BE and EAC is incompletely identified,suggesting potential underutilization of medical consultation.Raising public awareness of GERS as a risk factor for EAC is needed. 展开更多
关键词 Gastroesophageal reflux disease AWARENESS SELF-MANAGEMENT Help-seeking behavior Health promotion Patientreported outcomes
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Role of miRNAs from mesenchymal stem cell-derived extracellular vesicles in neuroinflammation and behavioral impairments induced by chronic alcohol consumption in female mice
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作者 Susana Mellado Najoua Touahri +6 位作者 Sandra Montagud-Romero Carla Perpiñá-Clérigues Francisco García-García Victoria Moreno-Manzano Consuelo Guerri Marta Rodríguez-Arias María Pascual 《Neural Regeneration Research》 2026年第6期2370-2379,共10页
Mesenchymal stem cell-derived extracellular vesicles have emerged as a promising form of regenerative and immunomodulatory therapy;indeed,micro(mi)RNAs contained within mesenchymal stem cell-derived extracellular vesi... Mesenchymal stem cell-derived extracellular vesicles have emerged as a promising form of regenerative and immunomodulatory therapy;indeed,micro(mi)RNAs contained within mesenchymal stem cell-derived extracellular vesicles modulate target gene expression and impact disease-associated pathways.Chronic alcohol consumption leads to neuroinflammation,brain damage,and impaired cognition.Evidence indicates that females are more vulnerable to alcohol-induced damage than males.While mesenchymal stem cell-derived extracellular vesicles have been studied in various neuroinflammatory conditions,their potential to counteract alcohol-induced brain damage remains unclear.In this study,we investigated whether repeated intravenous administration of mesenchymal stem cell-derived extracellular vesicles could ameliorate neuroinflammation and behavioral impairment induced by chronic alcohol consumption in female mice.Mesenchymal stem cell-derived extracellular vesicles diminished the increased binding of a micro-positron emission tomography tracer(^(18)F-FDG)when analyzing whole-brain 3D images and brain coronal sections of ethanol-treated mice.Mesenchymal stem cell-derived extracellular vesicle administration protected against ethanol-induced proinflammatory gene upregulation,cognitive dysfunction,and the conditioned rewarding effects of cocaine.MiRNA sequencing data from mesenchymal stem cell-derived extracellular vesicles revealed the elevated expression of extracellular vesicle-derived miR-483-5p and miR-140-3p in the brains of ethanol-treated female mice following mesenchymal stem cell-derived extracellular vesicle administration.In addition,mesenchymal stem cell-derived extracellular vesicles modulated the expression of pro-inflammatory-related miRNA target genes(e.g.,Socs3,Tnf,Mtor,and Atf6)in the brains of ethanol-treated female mice.These results suggest that mesenchymal stem cell-derived extracellular vesicles could function as a neuroprotective therapy to ameliorate the neuroinflammation,cognitive dysfunction,and conditioned rewarding effects of cocaine associated with chronic alcohol consumption. 展开更多
关键词 behavior chronic alcohol consumption cognitive ethanol extracellular vesicles female mesenchymal stem cells MIRNAS NEUROINFLAMMATION
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Exploring the Associations between Sedentary Time,Social Support,Social Rejection and Psychological Distress:A Network Analysis in Students
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作者 Yuyang Nie Kunkun Jiang +5 位作者 Tianci Wang Cong Liu Kangli Du Yuxian Cao Guofeng Qu Lijia Hou 《International Journal of Mental Health Promotion》 2026年第1期47-59,共13页
Background:Amid the global rise in adolescent sedentary behavior and psychological distress,extant research has largely focused on variable-level associations,neglecting symptom-level interactions.This study applies n... Background:Amid the global rise in adolescent sedentary behavior and psychological distress,extant research has largely focused on variable-level associations,neglecting symptom-level interactions.This study applies network analysis,aims to delineate the interconnections among sedentary time,social support,social exclusion,and psychological distress in Chinese students,and to identify core and bridge symptoms to inform targeted interventions.Methods:This study employed a cross-sectional design to investigate the complex relationships among sedentary behavior,social support,social exclusion,and psychological distress among Chinese students.The research involved 459 high school and university students,using network analysis and mediation models to examine these relationships.Results:Network analysis revealed that the network had a density of 58.33%and an average edge weight of 0.11.In terms of centrality,stress had the highest expected influence(EI=1.135),acting as the core amplifier in the network.Sedentary behavior demonstrated the highest bridging expected influence,functioning as a critical bridge for cross-community transmission.Conversely,friend support showed the lowest bridging EI with a negative value,indicating its effectiveness in blocking cross-community diffusion and alleviating symptoms.Conclusion:With stress acting as the most influential“core engine”within the symptom network and sedentary behavior serving as the key“bridge”for cross-community transmission,interventions should first target stress to weaken the overall symptom cascade,followed by reducing sedentary behavior or enhancing friend support to disrupt cross-community pathways,thereby achieving a core-bridge dual blockade. 展开更多
关键词 Sedentary behavior psychological distress social support social exclusion network analysis
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Characterizing the dynamic behavior and progressive damage evolution of carbonaceous slate under cyclic impact loading
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作者 Zhuang Li Nuwen Xu +4 位作者 Zhiqiang Sun Huabo Xiao Can Yang Huaizhong Liu Biao Li 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第2期1060-1072,共13页
Drilling and blasting tunneling is a cyclic process in which tunnel rock undergoes repeated blast loading,affecting its dynamic characteristics,energy evolution,and damage progression.To explore the dynamic mechanical... Drilling and blasting tunneling is a cyclic process in which tunnel rock undergoes repeated blast loading,affecting its dynamic characteristics,energy evolution,and damage progression.To explore the dynamic mechanical properties and damage mechanisms of carbonaceous slate under cyclic impact loads of varying intensities,cyclic dynamic tests are conducted using a triaxial split Hopkinson pressure bar.This study analyzes the stress-strain relationship,energy damage evolution,and macro-to-micro failure characteristics.The results show that peak stress and strain are significantly influenced by impact intensity and the number of impacts.The initial dynamic stress is positively correlated with the impact intensity,but with more impact,the dynamic stress decreases while the peak strain increases.Energy evolution follows a pattern of"slow growthfluctuating growthrapid growth,"with the crack initiation stress and its proportion decreasing.CT and SEM analyses reveal that as the impact intensity increases,failure becomes more chaotic,the fracture volume increases,and the fracture mode shifts from interlayer and intergranular to through-layer and trans-granular fractures.These findings provide an experimental basis for soft rock tunnel stability analysis. 展开更多
关键词 Split Hopkinson pressure bar Cyclic impact Dynamic behavior Cumulative damage MICROSTRUCTURE
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