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Integration of Fault Analysis and Interlock Controller Synthesis for Batch Processes 被引量:2
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作者 Susumu Hashizume Tomoyuki Yajima Yukiko Kuwashita Katsuaki Onogi 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2008年第1期57-61,共5页
Integration amongst various decision-making processes, such as planning, design, and operation is necessary to dynamic and flexible batch production. To achieve a batch production integration, utilization of common mo... Integration amongst various decision-making processes, such as planning, design, and operation is necessary to dynamic and flexible batch production. To achieve a batch production integration, utilization of common models used for various decision-making processes is an effective approach. From this point of view, a batch system common model as described by a Petri net is proposed. In this article, a fault diagnosis technique for batch processes is presented using information about fault propagation and the possibilities of integration of fault analysis and controller synthesis are discussed on the basis of the Petri net based common models. 展开更多
关键词 fault diagnosis batch control INTEGRATION discrete event system Petri net
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Studies on Composting Spent Coffee Grounds by <i>Aspergillus sp</i>and <i>Aspergillus sp</i>in Aerobic Static Batch Temperature Control 被引量:1
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作者 Asmak Afriliana Endar Hidayat +2 位作者 Yoshiharu Mitoma Taizo Masuda Hiroyuki Harada 《Journal of Agricultural Chemistry and Environment》 2021年第1期91-112,共22页
Spent Coffee Ground (SCG) is characterized by high organic content, in the form of insoluble polysaccharides bound and phenol compounds. Phenol compounds are toxic to nature and <span style="font-family:Verdan... Spent Coffee Ground (SCG) is characterized by high organic content, in the form of insoluble polysaccharides bound and phenol compounds. Phenol compounds are toxic to nature and <span style="font-family:Verdana;">are</span><span style="font-family:Verdana;"> a cause of environmental pollution. Composting method of this study is aerobic static batch composting with temperature control with adding activators of some fungi such as </span><i><span style="font-family:Verdana;">Aspergillus sp</span></i><span style="font-family:Verdana;">, and </span><i><span style="font-family:Verdana;">Penicillium sp. </span></i><span style="font-family:Verdana;">The purpose of the research is to fill the research gap from previous studies of spent coffee grounds compost, which requires a long time in composting, so that if it is used directly on the soil and plants, the positive effect also requires a long time. The result of composting for 28 days with this method is that mature compost has black crumb and normal pH, with characteristics of C/N ratio below 10: C1 (7.06), C2 (6.99). This value is far from the control with a C/N ratio of 8.33. Decompose rate of macromolecule are above 40% for lignin and 70% for cellulose. Implementation of compost in radish plants, resulting Germination Index above 80% which indicates that the compost is ripe: control (92.39%), C1 (183.88%), C2 (191.86%). The results of the analysis with FTIR also showed that the compost was mature and stable, and rich in minerals. So, it can be concluded </span><span style="font-family:Verdana;">that</span><span style="font-family:Verdana;"> this composting method can speed up composting time and optimize the results of compost produced.</span> 展开更多
关键词 Spent Coffee Ground (SCG) Aspergillus sp Aspergillus sp Aerobic Static batch Temperature control
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Modelling and Multi-Objective Optimal Control of Batch Processes Using Recurrent Neuro-fuzzy Networks 被引量:2
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作者 Jie Zhang 《International Journal of Automation and computing》 EI 2006年第1期1-7,共7页
In this paper, the modelling and multi-objective optimal control of batch processes, using a recurrent neuro-fuzzy network, are presented. The recurrent neuro-fuzzy network, forms a "global" nonlinear long-range pre... In this paper, the modelling and multi-objective optimal control of batch processes, using a recurrent neuro-fuzzy network, are presented. The recurrent neuro-fuzzy network, forms a "global" nonlinear long-range prediction model through the fuzzy conjunction of a number of "local" linear dynamic models. Network output is fed back to network input through one or more time delay units, which ensure that predictions from the recurrent neuro-fuzzy network are long-range. In building a recurrent neural network model, process knowledge is used initially to partition the processes non-linear characteristics into several local operating regions, and to aid in the initialisation of corresponding network weights. Process operational data is then used to train the network. Membership functions of the local regimes are identified, and local models are discovered via network training. Based on a recurrent neuro-fuzzy network model, a multi-objective optimal control policy can be obtained. The proposed technique is applied to a fed-batch reactor. 展开更多
关键词 Optimal control batch processes neural networks multi-objective optimisation.
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2D multi-model general predictive iterative learning control for semi-batch reactor with multiple reactions 被引量:2
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作者 BO Cui-mei YANG Lei +2 位作者 HUANG Qing-qing LI Jun GAO Fu-rong 《Journal of Central South University》 SCIE EI CAS CSCD 2017年第11期2613-2623,共11页
Batch to batch temperature control of a semi-batch chemical reactor with heating/cooling system was discussed in this study. Without extensive modeling investigations, a two-dimensional(2D) general predictive iterativ... Batch to batch temperature control of a semi-batch chemical reactor with heating/cooling system was discussed in this study. Without extensive modeling investigations, a two-dimensional(2D) general predictive iterative learning control(2D-MGPILC) strategy based on the multi-model with time-varying weights was introduced for optimizing the tracking performance of desired temperature profile. This strategy was modeled based on an iterative learning control(ILC) algorithm for a 2D system and designed in the generalized predictive control(GPC) framework. Firstly, a multi-model structure with time-varying weights was developed to describe the complex operation of a general semi-batch reactor. Secondly, the 2 D-MGPILC algorithm was proposed to optimize simultaneously the dynamic performance along the time and batch axes. Finally, simulation for the controller design of a semi-batch reactor with multiple reactions was involved to demonstrate that the satisfactory performance could be achieved despite of the repetitive or non-repetitive disturbances. 展开更多
关键词 two-dimensional system iterative learning control GENERAL PREDICTIVE control semi-batch REACTOR
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Batch Process Modelling and Optimal Control Based on Neural Network Model 被引量:6
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作者 JieZhang 《自动化学报》 EI CSCD 北大核心 2005年第1期19-31,共13页
This paper presents several neural network based modelling, reliable optimal control, and iterative learning control methods for batch processes. In order to overcome the lack of robustness of a single neural network,... This paper presents several neural network based modelling, reliable optimal control, and iterative learning control methods for batch processes. In order to overcome the lack of robustness of a single neural network, bootstrap aggregated neural networks are used to build reliable data based empirical models. Apart from improving the model generalisation capability, a bootstrap aggregated neural network can also provide model prediction confidence bounds. A reliable optimal control method by incorporating model prediction confidence bounds into the optimisation objective function is presented. A neural network based iterative learning control strategy is presented to overcome the problem due to unknown disturbances and model-plant mismatches. The proposed methods are demonstrated on a simulated batch polymerisation process. 展开更多
关键词 批量处理 神经网络模型 聚合 重复学习控制 最佳控制
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Re-Testing in Batch Testing Model Based on Quality Control Process for Proportion Estimation
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作者 Ronald Waliaula Wanyonyi Olivia Wanjeri Mwangi Charles Wambugu Mwangi 《Open Journal of Statistics》 2021年第1期123-136,共14页
The quality of products manufactured or procured by organizations is an important aspect of their survival in the global market. The quality control processes put in place by organizations can be resource-intensive bu... The quality of products manufactured or procured by organizations is an important aspect of their survival in the global market. The quality control processes put in place by organizations can be resource-intensive but substantial savings can be realized by using acceptance sampling in conjunction with batch testing. This paper considers the batch testing model based on the quality control process where batches that test positive are re-tested. The results show that re-testing greatly improves the efficiency over one stage batch testing based on quality control. This is observed using Asymptotic Relative Efficiency (ARE), where for values of </span><i><span style="font-family:Verdana;">p</span></i><span style="font-family:Verdana;"> computed ARE > 1 implying that our estimator has a smaller variance than the one-stage batch testing. Also, it was found that the model is more efficient than the classical two-stage batch testing for relatively high values of proportion. 展开更多
关键词 Quality control batch Testing Cut Off Value PROPORTION Re-Testing
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Run-to-run product quality control of batch processes
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作者 贾立 施继平 +1 位作者 程大帅 邱铭森 《Journal of Shanghai University(English Edition)》 CAS 2009年第4期267-269,共3页
Batch processes have been increasingly used in the production of low volume and high value added products. Consequently, optimization control in batch processes is crucial in order to derive the maximum benefit. In th... Batch processes have been increasingly used in the production of low volume and high value added products. Consequently, optimization control in batch processes is crucial in order to derive the maximum benefit. In this paper, a run-to-run product quality control based on iterative learning optimization control is developed. Moreover, a rigorous theorem is proposed and proven in this paper, which states that the tracking error under the optimal iterative learning control (ILC) law can converge to zero. In this paper, a typical nonlinear batch continuous stirred tank reactor (CSTR) is considered, and the results show that the performance of trajectory tracking is gradually improved by the ILC. 展开更多
关键词 iterative learning optimization control tracking error batch processes
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Guaranteed Cost Iterative Learning Control for Multi-Phase Batch Processes
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作者 WANG Limin WANG Runze +4 位作者 XIONG Yuting WANG Haosen ZHU Lin ZHANG Ke GAO Furong 《Journal of Shanghai Jiaotong university(Science)》 EI 2018年第6期811-819,共9页
Batch process is a typical multi-phase process. Due to the interaction between the phases of the batch process, high precision control in a single phase cannot guarantee high precision control of the whole batch proce... Batch process is a typical multi-phase process. Due to the interaction between the phases of the batch process, high precision control in a single phase cannot guarantee high precision control of the whole batch process. In order to solve this problem, the guaranteed cost iterative learning control(ILC) of multi-phase batch processes is studied in this paper. Firstly, through introducing the output error, the state error and the extended information, the multi-phase batch process is transformed into an equivalent 2D switched system which has different dimensions. In addition, under the measurable condition, the guaranteed cost iterative learning control law with extended information is designed. The proposed control law ensures not only the stability of the system but also the optimal control performance. Next, in order to study the stability of the system and the minimum running time under the condition of stable running, the multi-Lyapunov function method is used. By means of the average dwell time method, the sufficient conditions ensuring system to be exponentially stable are given in the form of linear matrix inequality(LMI). Finally, the injection molding process is taken as an example to make simulation, which shows the feasibility and effectiveness of the proposed method. 展开更多
关键词 MULTI-PHASE batch process iterative learning control (ILC) AVERAGE DWELL time hybrid guaranteed cost controller
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Predictive Sliding Mode Control to a Thermal Process for Batch Dyeing
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作者 张建新 俞利国 《Journal of Donghua University(English Edition)》 EI CAS 2012年第2期182-186,共5页
The batch dyeing process is a typical nonlinear process with time-delay,where precise controlling of temperature plays a vital role on the dyeing quality.Because the accuracy and robustness of the commonly used propor... The batch dyeing process is a typical nonlinear process with time-delay,where precise controlling of temperature plays a vital role on the dyeing quality.Because the accuracy and robustness of the commonly used proportion integration differentiation(PID) algorithm had been limited,a novel method was developed to precisely control the heating and cooling stages for batch dyeing process based on predictive sliding mode control(SMC) algorithm.Firstly,a special predictive sliding mode model was constructed according to the principle of generalized predictive control(GPC);secondly,an appropriate reference trajectory for SMC was designed based on the improved approaching law;finally,the predictive sliding mode model and the Diophantine equation were used to predict the output and then the optimized control law was derived using the generalized predictive law.This method combined GPC and the SMC with their respective advantages,so it could be applied to time-delay process,making the control system more robust.Simulation experiments show that this algorithm can well track the temperature variation for the batch dyeing process. 展开更多
关键词 temperature control generalized predictive control(GPC) sliding mode control(SMC) batch dyeing process
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Model-Based Split-Range Algorithm for the Temperature Control of a Batch Reactor
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作者 Miklós Gábor Balaton Lajos Nagy Ferenc Szeifert 《Engineering(科研)》 2012年第9期515-525,共11页
In the manufacturing processes of high value-added products in the pharmaceutical, fine chemical polymer and food industry, insufficient control might produce off-grade products. This can cause significant financial l... In the manufacturing processes of high value-added products in the pharmaceutical, fine chemical polymer and food industry, insufficient control might produce off-grade products. This can cause significant financial losses, or in the pharmaceutical industry, it can result in an unusable batch. In these industries, batch reactors are commonly used, the control of which is essentially a problem of temperature control. In the industry, an increasing number of heating-cooling systems utilising three different temperature levels can be found, which are advantageous from an economic point of view. However, it makes the control more complicated. This paper presents a split-range designing technique using the model of the controlled system with the aim to design a split-range algorithm more specific to the actual sys- tem. The algorithm described provides high control performance when using it with classical PID-based cascade temperature control of jacketed batch reactors;however, it can be used with or as part of other types of controllers, for ex- ample, model-based temperature controllers. The algorithm can be used in the case of systems where only two as well as where three temperature levels are used for temperature control. Besides the switching between the modes of opera- tion and calculating the value of the manipulated variable, one of the most important functions of the split-range algo- rithm is to keep the sign of the gain of the controlled system unchanged. However, with a more system-specific split-range solution, not only can the sign of the gain be kept unchanged, but the gain can also be constant or less de- pendent on the state of the system. Using this solution, the design of the PID controller becomes simpler and can be implemented in existing systems without serious changes. 展开更多
关键词 batch REACTOR MODEL-BASED control Split-Range Monofluid Thermoblock Temperature control
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间歇生产工艺自动化率评估
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作者 朱东利 《石油化工自动化》 2026年第1期27-31,64,共6页
介绍了间歇生产过程安全自动化、工艺控制自动化、全操作自动化现状,分析了原料药企业未实现顺控操作的原因。以反应釜典型操作单元为例,介绍了顺控流程和顺控文档编制的方法及注意事项。阐述了自动化率评估的流程,详细介绍如何确定分... 介绍了间歇生产过程安全自动化、工艺控制自动化、全操作自动化现状,分析了原料药企业未实现顺控操作的原因。以反应釜典型操作单元为例,介绍了顺控流程和顺控文档编制的方法及注意事项。阐述了自动化率评估的流程,详细介绍如何确定分析范围,以及如何评估间歇工艺的自动化率,根据评估结果提出优化建议。 展开更多
关键词 化学合成原料药 自动化率 顺序控制 批控制 间歇生产
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基于ControlLogix平台的配料系统设计研究
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作者 张艳丰 《济源职业技术学院学报》 2008年第1期28-30,共3页
开磷集团HGB项目的配料系统是以ControlLogix为硬件平台和ControlNet为网络平台,将PLC、变频器、触摸屏、称重仪表连接成一个统一的整体,对配料系统的各种机电设备进行就地/远程控制和监测,从而完成了对配料的自动化,在国内具有领先水... 开磷集团HGB项目的配料系统是以ControlLogix为硬件平台和ControlNet为网络平台,将PLC、变频器、触摸屏、称重仪表连接成一个统一的整体,对配料系统的各种机电设备进行就地/远程控制和监测,从而完成了对配料的自动化,在国内具有领先水平。对其他行业的配料控制亦有很好的借鉴和指导作用。 展开更多
关键词 controlLOGIX 控制网 配料
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基于PCS7的BATCH控制在生物制药单抗生产中的应用 被引量:6
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作者 王磊 《流体测量与控制》 2023年第2期92-97,共6页
随着生物制药的发展,单抗药物的生产越来越朝着系统化、集成化、数字化的方向发展。针对单抗药物复杂的工艺生产过程和配方多变的生产方式。本文采用西门子PCS7全集成DCS系统,利用符合ISA-S88标准的批量控制软件和配方管理,研究单抗控... 随着生物制药的发展,单抗药物的生产越来越朝着系统化、集成化、数字化的方向发展。针对单抗药物复杂的工艺生产过程和配方多变的生产方式。本文采用西门子PCS7全集成DCS系统,利用符合ISA-S88标准的批量控制软件和配方管理,研究单抗控制方案和第三方设备集成方案,设计出适用于单抗生产的批次控制DCS系统,满足其生产工艺、参数多变的柔性化需求和数据完整性要求。 展开更多
关键词 batch控制 PCS7 单抗 S88 配方控制
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EBR系统在血液制品行业的实践应用
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作者 詹佳刚 石林龙 李洪强 《数字化转型》 2026年第1期95-103,共9页
随着血液制品行业数字化转型的加速,电子批记录(EBR)系统成为提升生产管理水平与合规性的关键支撑。文章以国产平台搭建的EBR系统为研究对象,结合血液制品行业“工艺复杂、质控严苛、追溯性强”的特性,深入剖析EBR系统的应用模式、实施... 随着血液制品行业数字化转型的加速,电子批记录(EBR)系统成为提升生产管理水平与合规性的关键支撑。文章以国产平台搭建的EBR系统为研究对象,结合血液制品行业“工艺复杂、质控严苛、追溯性强”的特性,深入剖析EBR系统的应用模式、实施路径、应用优势及应对策略,揭示其在合规性强化、生产效率提升、质量控制优化等维度的作用机制。研究表明,基于国产平台的EBR系统可通过设备深度集成、业务模块定制化开发,实现对血液制品全流程数据的闭环管理。同时,通过科学的验证体系与人员培训机制,可有效解决系统集成复杂性、人员适应困难等实施难题,为血液制品行业数字化转型提供可复制的实践参考,助力行业迈向智能化生产新阶段。 展开更多
关键词 电子批记录(EBR)系统 血液制品行业 数字化转型 质量控制 法规合规
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Automatic Synthesis of Batch Process Operating Procedures
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作者 王保国 王春艳 +1 位作者 许锡恩 Allen R.Wright 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 1998年第1期46-53,共8页
A three-step synthesis strategy for the automatic synthesis of operating procedures in batch processoperations is presented in this paper.The first step is pre-operation which consists of a set of checks that mustbe c... A three-step synthesis strategy for the automatic synthesis of operating procedures in batch processoperations is presented in this paper.The first step is pre-operation which consists of a set of checks that mustbe considered before starting the basic process operation.The second step is operation which is described by a setof basic control instructions.The third step is post-operation described by a set of instructions that must becarried out when the basic process operation is terminated.The three-step synthesis method has been imple-mented as part of a prototype recipe management system. 展开更多
关键词 batch PROCESS operating PROCEDURE control STEP
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Learning control of fermentation process with an improved DHP algorithm
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作者 Dazi Li Ningjia Meng Tianheng Song 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2016年第10期1399-1405,共7页
Control of the fed-batch ethanol fermentation processes to produce maximum product ethanol is one of the key issues in the bioreactor system.However,ethanol fermentation processes exhibit complex behavior and nonlinea... Control of the fed-batch ethanol fermentation processes to produce maximum product ethanol is one of the key issues in the bioreactor system.However,ethanol fermentation processes exhibit complex behavior and nonlinear dynamics with respect to the cell mass,substrate,feed-rate,etc.An improved dual heuristic programming algorithm based on the least squares temporal difference with gradient correction(LSTDC) algorithm(LSTDC-DHP) is proposed to solve the learning control problem of a fed-batch ethanol fermentation process.As a new algorithm of adaptive critic designs,LSTDC-DHP is used to realize online learning control of chemical dynamical plants,where LSTDC is commonly employed to approximate the value functions.Application of the LSTDC-DHP algorithm to ethanol fermentation process can realize efficient online learning control in continuous spaces.Simulation results demonstrate the effectiveness of LSTDC-DHP,and show that LSTDC-DHP can obtain the near-optimal feed rate trajectory faster than other-based algorithms. 展开更多
关键词 Dual heuristic programming batch process Ethanol fermentation process Learning control
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I/A Batch在精细化工装置上的应用
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作者 顾珏 《中国仪器仪表》 2006年第3期65-68,共4页
本文介绍了I/ABatch软件的技术以及在国内某精细化工装置上的应用,并介绍了有关的硬件构架、软件组成,尤其是PHASE逻辑及配方管理。
关键词 I/A batch DDC 批量控制 PHASE逻辑 RECIPE管理
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Proficy Batch软件在烟草制丝线中的应用
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作者 尤芳胜 《工业控制计算机》 2014年第4期114-115,共2页
GE公司有着许多自动化产品,而Proficy Batch便是其中的佼佼者。Proficy Batch是一款有着高性能的自动化批次处理软件,可以在短时间内将复杂的工厂工艺建立成模型,并构建配方,实现批次管理功能。随着Proficy Batch软件的成型和发展升级,P... GE公司有着许多自动化产品,而Proficy Batch便是其中的佼佼者。Proficy Batch是一款有着高性能的自动化批次处理软件,可以在短时间内将复杂的工厂工艺建立成模型,并构建配方,实现批次管理功能。随着Proficy Batch软件的成型和发展升级,Proficy Batch软件受到了越来越多的公司的青睐。 展开更多
关键词 批次处理 配方 烟草
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Monitoring Saccharification Process in Brewery Industry Using Quality Control Charts
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作者 Samwel Manyele Nyakorema Rioba 《Engineering(科研)》 2016年第7期481-498,共18页
The aim of this study was to establish a control system for saccharification process using quality control charts. To achieve this goal, temperature, pH and brix were measured at 12 minutes intervals for 15 consecutiv... The aim of this study was to establish a control system for saccharification process using quality control charts. To achieve this goal, temperature, pH and brix were measured at 12 minutes intervals for 15 consecutive batches which took 2 hours each. The time variations for three process parameters were assessed to establish a good understanding of the saccharification process. The temperature varied between 58℃ and 62℃ while the pH decreased slowly due to oxidation, values of which varied between 5.7 and 5.0. Brix values increased linearly with time. The initial and final values of the three parameters varied from one batch to another. Of the three parameters, brix was not well represented on the quality control charts due to wide difference between initial and final values during saccharification. The final brix values varied between batches, from 10.6% to 11.6%. The control charts used in this study were X-bar and Range charts. The rules for interpreting control charts were implemented for both X-bar and R charts, results of which showed that the process was out of control, although some rules were not violated due to little number of batches studied. The values of for temperature and pH data (2.27℃ and 0.35, respectively) were lower compared to brix data (11.2%). The corresponding values of span between control limits, SP<sub>x</sub> and SP<sub>R</sub> for temperature and pH were also comparatively lower than those established from brix data. Due to larger values of for brix measurements, the corresponding control charts for brix were insensitive in identifying out-of-control points during saccharification process. 展开更多
关键词 SACCHARIFICATION batch Processing Statistical Process control control Charts control Limits Number of Subgroups
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抗程序性死亡受体1单抗关键质控项目的趋势分析
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作者 杨雅岚 祁志云 +3 位作者 刘春雨 崔永霏 郭璐韵 于传飞 《中国药事》 2025年第7期779-787,共9页
目的:对抗程序性死亡受体1(PD-1)单抗关键质控项目检测结果进行趋势分析,以评价抗PD-1单抗的批间一致性和稳定性。方法:分别将中国食品药品检定研究院(NIFDC)和某企业对93批抗PD-1单抗关键质控项目检测结果进行统计和趋势分析,包括SEC... 目的:对抗程序性死亡受体1(PD-1)单抗关键质控项目检测结果进行趋势分析,以评价抗PD-1单抗的批间一致性和稳定性。方法:分别将中国食品药品检定研究院(NIFDC)和某企业对93批抗PD-1单抗关键质控项目检测结果进行统计和趋势分析,包括SEC单体含量、HIC前峰(1+2)含量、生物学活性、蛋白含量和pH,建立警戒限和行动限,并对异常结果进行调查分析。结果:2家实验室的SEC单体含量测定结果均在99.7%~99.9%;蛋白含量、生物学活性和pH均在行动限范围内;企业和NIFDC检测的HIC前峰(1+2)含量平均值分别是(5.42±0.33)%和(5.44±0.34)%;对2家实验室的生物学活性和蛋白含量测定结果作统计学分析,结果无统计学差异;基于以上趋势分析和统计学分析,发现某企业HIC前峰(1+2)含量检测结果呈现逐年升高的趋势,NIFDC及时告知该企业启动原因调查与风险评估。结论:本研究采用的趋势分析和统计学分析相结合的质量监测策略有效识别了抗PD-1单抗生产及检测过程中潜在的质量波动风险,为确保抗PD-1单抗批间一致性及临床用药安全性提供了关键质量保障。 展开更多
关键词 抗PD-1单抗 质量控制 趋势分析 批间一致性
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