The bicyclic cryptand 1,4,7, 10,13,16,21, 24-octaaza-bigcyclo [8, 8,8] hexacosan-3, 8, 12, 17, 20, 25-hex-one (COBH) bearing diaminoethane groups along the eight-atom bridges was synthesized. The structure consists of...The bicyclic cryptand 1,4,7, 10,13,16,21, 24-octaaza-bigcyclo [8, 8,8] hexacosan-3, 8, 12, 17, 20, 25-hex-one (COBH) bearing diaminoethane groups along the eight-atom bridges was synthesized. The structure consists of discrete neutral macrobicyclic units; the two cycles share the two tertiary amine nitrogen atoms, which exhibit an endo-cndo conformation. Three identical branches formed by 1, 2-diaminoethane link the two tertiary amine groups. The protonation reactions of cryptand (COBH) and its complex formation with copper (II) were investigated by potentiometry in water and in a DMSO/water (80:20 in mass ratio) mixture as solvents. The cryptand acts as a his-base through its two N-bridgehead and exhibits a strong cooperativity that favors the first protonation and makes the second one difficult (△pK= 5.0). An inward rotation of the amide groups to form hydrogen bonds accounts for this cooperativity. The interaction of COBH with copper (II) leads to several binuclear complex proton contents.展开更多
Up to now,how the secretion modes of intestinal fluid(i.e.,pancreaticobiliary secretion and wall secretion)can regulate intestinal acid-base environment has not been fully understood.Understanding the regulation mecha...Up to now,how the secretion modes of intestinal fluid(i.e.,pancreaticobiliary secretion and wall secretion)can regulate intestinal acid-base environment has not been fully understood.Understanding the regulation mechanism is not only of great significance for intestinal health but may also lead to optimized designs for bio-inspired soft elastic reactors(SERs).In this work,the mixing and reaction of acidic gastric juice and alkaline intestinal fluid in a 3D duodenum with moving walls were modelled.A unique feature of this model is the implementation of both pancreaticobiliary and wall secretion of intestinal fluid as boundary conditions.This model allowed us to quantitatively explore the influence of secretion modes on pH regulation.The results demonstrated that coexistence of both pancreaticobiliary and wall secretions is the key to maintain the average pH in the duodenum at about 7.4.Their coexistence synergistically promotes the mixing and reaction of acid-base digestion liquids and provides a suitable catalytic environment for lipase in the intestine.展开更多
Water management within the membrane electrode assemblies(MEAs)of electrochemical hydrogen compressors(EHCs)plays a crucial role in optimizing overall performance,particularly under low relative humidity(RH),where the...Water management within the membrane electrode assemblies(MEAs)of electrochemical hydrogen compressors(EHCs)plays a crucial role in optimizing overall performance,particularly under low relative humidity(RH),where the anode side tends to dry out.Hollow mesoporous silica nanoparticles functionalized with amino groups(HMSNs-NH_(2))were integrated into the anode catalyst layers of EHCs to establish humidity-independent proton pathways through acid-base interactions with Nafion ionomers.These acid-base pairs between grafted–NH_(2)and sulfonic acid groups create continuous“proton highways”,enabling efficient conduction via the Grotthuss mechanism even at 50%RH.With only 2.5 wt%HMSNs-NH_(2)in the anode catalyst layer,hydrogen was compressed to 0.9 MPa in 60±3 s at 50%RH,representing a 55%reduction in compression time compared to MEAs with conventional Pt/C catalyst layers under the same conditions.This work overcomes the critical water-management bottleneck in EHCs,advancing the deployment of hydrogen energy technologies in arid environments.展开更多
The most widely used bisphenol A-type epoxy resin(DGEBA)in electrical engineering demonstrates excellent mechanical and electrical properties.However,the insoluble and infusible characteristics of cured DGEBA make it ...The most widely used bisphenol A-type epoxy resin(DGEBA)in electrical engineering demonstrates excellent mechanical and electrical properties.However,the insoluble and infusible characteristics of cured DGEBA make it difficult to efficiently degrade and recycle decommissioned electrical equipment.In this study,a degradable itaconic acid-based epoxy resin incorporating dynamic covalent bonds was prepared through the integration of ester bonds and disulfide bonds,with itaconic acid as the precursor.The covalent bonding effects on the mechanical,thermal,electrical,and degradation characteristics were systematically evaluated.The experimental results revealed that the introduction of dynamic ester bonds enhanced the mechanical properties and thermal stability of the resin system,achieving a flexural strength of 141.57 MPa and an initial decomposition temperature T_(5%)of up to 344.9℃.The resin system containing dynamic disulfide bonds exhibited a dielectric breakdown strength of 41.11 k V/mm.Simultaneously,the incorporation of disulfide bonds endowed the epoxy resin with remarkable degradability,enabling complete dissolution within 1.5 h at 90℃ in a mixed solution of dithiothreitol(DTT)and N-methylpyrrolidone(NMP).This research provides a valuable reference for the application of itaconic acid-based vitrimer with dynamic covalent bonds in electrical materials,contributing to the development and utilization of environmentally friendly electrical equipment.展开更多
Behavior recognition of Hu sheep contributes to their intensive and intelligent farming.Due to the generally high density of Hu sheep farming,severe occlusion occurs among different behaviors and even among sheep perf...Behavior recognition of Hu sheep contributes to their intensive and intelligent farming.Due to the generally high density of Hu sheep farming,severe occlusion occurs among different behaviors and even among sheep performing the same behavior,leading to missing and false detection issues in existing behavior recognition methods.A high-low frequency aggregated attention and negative sample comprehensive score loss and comprehensive score soft non-maximum suppression-YOLO(HLNC-YOLO)was proposed for identifying the behavior of Hu sheep,addressing the issues of missed and erroneous detections caused by occlusion between Hu sheep in intensive farming.Firstly,images of four typical behaviors-standing,lying,eating,and drinking-were collected from the sheep farm to construct the Hu sheep behavior dataset(HSBD).Next,to solve the occlusion issues,during the training phase,the C2F-HLAtt module was integrated,which combined high-low frequency aggregation attention,into the YOLO v8 Backbone to perceive occluded objects and introduce an auxiliary reversible branch to retain more effective features.Using comprehensive score regression loss(CSLoss)to reduce the scores of suboptimal boxes and enhance the comprehensive scores of occluded object boxes.Finally,the soft comprehensive score non-maximal suppression(Soft-CS-NMS)algorithm filtered prediction boxes during the inferencing.Testing on the HSBD,HLNC-YOLO achieved a mean average precision(mAP@50)of 87.8%,with a memory footprint of 17.4 MB.This represented an improvement of 7.1,2.2,4.6,and 11 percentage points over YOLO v8,YOLO v9,YOLO v10,and Faster R-CNN,respectively.Research indicated that the HLNC-YOLO accurately identified the behavior of Hu sheep in intensive farming and possessed generalization capabilities,providing technical support for smart farming.展开更多
To investigate the influence of Al-Zn-Mg-Cu alloy with as-homogenized and as-rolled initial microstructures on the tensile flow behavior,isothermal tensile tests were conducted on a GLEEBLE-3500 isothermal simulator a...To investigate the influence of Al-Zn-Mg-Cu alloy with as-homogenized and as-rolled initial microstructures on the tensile flow behavior,isothermal tensile tests were conducted on a GLEEBLE-3500 isothermal simulator at temperatures of 380-440℃and strain rates of 0.05-1 s^(−1).The Johnson-Cook model,Hensel-Spittel model,strain-compensated Arrhenius model,and critical fracture strain model were established.Results show that through the evaluation of the models using the correlation coefficient(R)and the average absolute relative error,the strain-compensated Arrhenius model can represent the flow behavior of the alloy more accurately.Shear bands are more pronounced in the as-homogenized specimens,whereas dynamic recrystallization is predominantly observed in as-rolled specimens.Fracture morphology analysis reveals that a mixed fracture mechanism is prevalent in the as-homogenized specimen,whereas a ductile fracture mechanism is predominant in the as-rolled specimen.The processing maps indicate that the unstable region is reduced in the as-rolled specimens compared with that in the as-homogenized specimens.The optimal hot working windows for the as-homogenized and as-rolled specimens are determined as 410-440℃/0.14-1 s^(−1)and 380-400℃/0.05-0.29 s^(−1),respectively.展开更多
Correction to:Nano-Micro Letters(2026)18:10.https://doi.org/10.1007/s40820-025-01852-8 Following publication of the original article[1],the authors reported that the last author’s name was inadvertently misspelled.Th...Correction to:Nano-Micro Letters(2026)18:10.https://doi.org/10.1007/s40820-025-01852-8 Following publication of the original article[1],the authors reported that the last author’s name was inadvertently misspelled.The published version showed“Hongzhen Chen”,whereas the correct spelling should be“Hongzheng Chen”.The correct author name has been provided in this Correction,and the original article[1]has been corrected.展开更多
Residential energy-use behavior and energy-saving awareness play a crucial role in sustainable urban energy planning and building energy efficiency,particularly under the pressures of climate change.However,existing s...Residential energy-use behavior and energy-saving awareness play a crucial role in sustainable urban energy planning and building energy efficiency,particularly under the pressures of climate change.However,existing studies often lack comparative analysis of urban-rural differences and tend to focus excessively on behavior patterns while neglecting the dimension of energysaving awareness.With China’s urbanization rate reaching 66.16%,understanding such regional disparities has become increasingly important.To address these research gaps,this study conducts a large-scale survey on space cooling behaviors among residents in Beijing,a representative Chinese megacity.It should be noted that living standards in such megacities are generally higher than the national average,which may shape distinctive energy-use profiles.Analyzing 1573valid samples(1064 urban/442 rural)in 2024,this study employed K-Prototypes and K-Modes clustering to identify typical cooling behavior and energy-saving awareness pattems,followed by Kendall/Chi-square correlation tests and XGBoost importance analysis to determine key influencing factors,with subsequent urban-rural comparative analysis.Results indicate that urban residents are primarily heat-sensitive or heat-tolerant,with a secondary patten of mid-low temperature preference,and generally exhibit long cooling durations;rural behavior is dominated by heat-tolerant type,followed by heat-sensitive,mid-low temperature preference,and never-on types as secondary patterns;both urban and rural areas exhibit energy-savingawareness characterized by low consumption-lowwillingness,though urban areas show marginally higher motivation;energy-saving awareness correlates with cooling behavior in rural areas,but this relationship weakens significantly in urban contexts.展开更多
With the rapid development of smart manufacturing,intelligent safety monitoring in industrial workshops has become increasingly important.To address the challenges of complex backgrounds,target scale variation,and exc...With the rapid development of smart manufacturing,intelligent safety monitoring in industrial workshops has become increasingly important.To address the challenges of complex backgrounds,target scale variation,and excessive model parameters in worker violation detection,this study proposes ADCP-YOLO,an enhanced lightweight model based on YOLOv8.Here,“ADCP”represents four key improvements:Alterable Kernel Convolution(AKConv),Dilated-Wise Residual(DWR)module,Channel Reconstruction Global Attention Mechanism(CRGAM),and Powerful-IoU loss.These components collaboratively enhance feature extraction,multi-scale perception,and localization accuracy while effectively reducing model complexity and computational cost.Experimental results show that ADCP-YOLO achieves a mAP of 90.6%,surpassing YOLOv8 by 3.0%with a 6.6%reduction in parameters.These findings demonstrate that ADCP-YOLO successfully balances accuracy and efficiency,offering a practical solution for intelligent safety monitoring in smart factory workshops.展开更多
This study utilizes wet/dry cyclic corrosion testing combined with corrosion big data technology to investigate the mechanism by which chloride ions(Cl^(-))influence the corrosion behavior of 650 MPa high-strength low...This study utilizes wet/dry cyclic corrosion testing combined with corrosion big data technology to investigate the mechanism by which chloride ions(Cl^(-))influence the corrosion behavior of 650 MPa high-strength low-alloy(HSLA)steel in industrially polluted environments.The corrosion process of 650 MPa HSLA steel occurred in two distinct stages:an initial corrosion stage and a stable corrosion stage.During the initial phase,the weight loss rate increased rapidly owing to the instability of the rust layer.Notably,this study demonstrated that 650 MPa HSLA steel exhibited superior corrosion resistance in Cl-containing environments.The formation of a corrosion-product film eventually reduced the weight-loss rate.However,the intrusion of Cl^(-)at increasing concentrations gradually destabilized theα/γ^(*)phases of the rust layer,leading to a looser structure and lower polarization resistance(R_(p)).The application of corrosion big data technology in this study facilitated the validation and analysis of the experimental results,offering new insights into the corrosion mechanisms of HSLA steel in chloride-rich environments.展开更多
Flight behavior analysis provides the fundamental basis for the future development of air traffic management(ATM).The characteristics of aircraft behavior are inherently reflected in their flight trajectories,impactin...Flight behavior analysis provides the fundamental basis for the future development of air traffic management(ATM).The characteristics of aircraft behavior are inherently reflected in their flight trajectories,impacting flight efficiency and safety levels.However,existing research largely addresses inefficient or abnormal trajectories from a single perspective,with an absence of a unified evaluation standard.This paper introduces a method for analyzing flight deviation behavior based on automatic dependent surveillance-broadcast(ADS-B)data,defining novel metrics of trajectory redundancy and trajectory deviation.An adaptive detection algorithm is developed to capture diverse deviation patterns.Results reveal that higher trajectory redundancy is linked to lower operational efficiency,while trajectory deviation effectively identify stepped descents,holding patterns,detours,and other behaviors.The approach offers data-driven support for anomaly detection,performance evaluation and air traffic management,with substantial significance for civil aviation applications.展开更多
Urbanization destroys wildlife habitats,fragmenting them into small patches with poor connectivity,leading to population declines in species sensitive to such chan ges.Escape is the most common anti-predator strategy ...Urbanization destroys wildlife habitats,fragmenting them into small patches with poor connectivity,leading to population declines in species sensitive to such chan ges.Escape is the most common anti-predator strategy adopted by birds,refuges in habitats reduce or eliminate predation risk.Therefore,creating habitats with suitable refuges for birds has significant implications for their conservation.However,there have been few studies on refuge selection in birds.This study examined the Eurasian Tree Sparrow(Passer montanus)and Oriental Magpie(Pica serica)in urban and rural areas of Chengde City,northern China by measuring their alert distance(AD),flight initiation distance(FID),an d distance fled(DF)and analyzed their refuge selection characteristics after escaping.The FID/AD ratio was employed to assess the behavioral differences of birds in the risk trade-off.The results showed that the FID and FID/AD of both species were lower in urban areas than in rural areas and were negatively correlated with immediate human density.Sparrow FID was significantly affected by group size and landing substrate type.The FID of sparrows was positively correlated with the group size.The sparrows that fled to bushes escaped earlier.In urban and rural areas,sparrows exhibited significantly lower FID,DF,and FID/AD than magpies.The species adopted different refuge selection strategies,with magpies preferentially selecting trees with greater vertical height and sparrows selecting both trees and bushes.Further analysis indicated that the horizontal and vertical distances fled of both species were lower when fleeing to bushes.Urban planning and conservation areas construction should incorporate the ecological needs of local bird species to rationally configure their habitat structure,thereby optimizing the effect of avian conservation.展开更多
High-performance magnesium alloys are in great demand to meet the lightweight design requirements of aircraft.Grain size has long been recognized as a key factor influencing the mechanical properties of alloys.This st...High-performance magnesium alloys are in great demand to meet the lightweight design requirements of aircraft.Grain size has long been recognized as a key factor influencing the mechanical properties of alloys.This study investigates the effect of grain size,controlled by Zr addition,on the fatigue behavior of a recently developed low-cost Mg-2.6Nd-0.35Zn alloy,through systematic characterization and analysis of stress-life(S-N)curves,fatigue crack propagation,fracture surface morphology,stress intensity factor,and crack propagation threshold.The results show that after heat treatment(solution at 525±5℃ for 8 h and water quenching at 60-80℃,followed by aging at 250±5℃for 14 h and then air cooling),coarse-grained specimens(average grain size approximately 596μm)containing 0.12wt.%Zr exhibit greater resistance to fatigue crack propagation than fine-grained specimens(average grain size approximately 94μm)containing 0.46wt.%Zr.Coarse grains promote intergranular fracture,while fine grains favor transgranular fracture.In addition,coarse grains reduce the sensitivity of the crack tip to stress concentration.Furthermore,fine-grained samples demonstrate a longer total fatigue life,owing to their superior resistance to crack initiation,which significantly prolongs the crack initiation stage.These findings highlight the importance of optimizing grain size to achieve the best possible fatigue resistance in Mg-Nd-Zn-Zr alloys for practical engineering applications.展开更多
BACKGROUND Despite societal guidelines recommending targeted screening for Barrett’s esophagus(BE)and esophageal adenocarcinoma(EAC)in individuals with gastroesophageal reflux symptoms(GERS),screening adherence is su...BACKGROUND Despite societal guidelines recommending targeted screening for Barrett’s esophagus(BE)and esophageal adenocarcinoma(EAC)in individuals with gastroesophageal reflux symptoms(GERS),screening adherence is suboptimal.Current screening approaches fail to identify individuals not seeking medical consultation for GERS or whose GERS are managed with‘over-the-counter’(OTC)acid suppressant therapies.AIM To assess patients’self-management and help-seeking behavior for GERS.METHODS This cross-sectional study collected data from the Dutch general population aged 18-75 years between January and April 2023 using a web-based survey.The survey included questions regarding self-management(e.g.,use of acid suppressant therapy with or without prescription)and help-seeking behavior(e.g.,consulting a primary care provider)for GERS.Simple random sampling was performed to select individuals within the target age group.In total,18156 randomly selected individuals were invited to participate.The study protocol was registered in ClinicalTrials.gov(identifier:NCT05689918).RESULTS Of the 18156 invited individuals,3214 participants(17.7%)completed the survey,of which 1572 participants(48.9%)reported GERS.Of these,904 participants(57.5%)had never consulted a primary care provider for these symptoms,of which 331 participants(36.6%)reported taking OTC acid suppressant therapy in the past six months and 100 participants(11.1%)fulfilled the screening criteria for BE and EAC according to the European Society of Gastrointestinal Endoscopy Guideline.CONCLUSION The population fulfilling the screening criteria for BE and EAC is incompletely identified,suggesting potential underutilization of medical consultation.Raising public awareness of GERS as a risk factor for EAC is needed.展开更多
There is a strong coupling relationship between the friction characteristics of the ball-groove interface and the ball motion behavior.However,available studies tend to consider ball motion and frictional behavior sep...There is a strong coupling relationship between the friction characteristics of the ball-groove interface and the ball motion behavior.However,available studies tend to consider ball motion and frictional behavior separately.In this paper,a unified tribology-kinematic model is established considering the coupling effect between friction and the ball velocity vector.The friction in ball-groove contact and ball speed are simultaneously measured by a newly developed disc-ball-disc device for studying friction and movement in ball screws.A comprehensive analysis of rubbing interface behavior and ball motion is conducted.The results show that the coupling effect between friction in ball-groove contact and ball motion is quite obvious.The sliding velocity of the ball is much higher with coupling effect than that when ignoring coupling influence,especially at high-speed conditions.The friction in ball-groove contact decreases at first and then shows a dramatic increase with the gradual rise of rotation speed,which is caused by the coupling variation of sliding speed.The studies show that the disc-ball-disc approach is an innovative and valuable method to investigate friction and ball motion in ball screws.展开更多
To investigate the aging mechanisms and elucidate the correlations between unstable microstructure and performance in biodegradable Zn alloys,the accelerated aging experiment was conducted on a high-performance wrough...To investigate the aging mechanisms and elucidate the correlations between unstable microstructure and performance in biodegradable Zn alloys,the accelerated aging experiment was conducted on a high-performance wrought Zn−0.1Mg alloy by annealing at 200℃ for varying durations.The findings reveal that the tensile strength of the alloy rapidly and significantly declines with prolonged annealing time,decreasing from 383 MPa for the as-received alloy to 102 MPa for the alloy subjected to 1440 min of annealing.The primary factors contributing to this considerable reduction in strength are static recrystallization,grain coarsening,and dislocation annihilation.Initially,the ductility of the alloy shows fluctuations,ultimately experiencing a marked decrease after extended annealing.This decline is linked to the grain growth and heightened texture intensity,while the unusual increase in ductility observed between 30 and 120 min of annealing is likely due to the formation of twins.In addition,due to rapid grain growth and an increase in precipitates and twins,the corrosion resistance of the alloy in Hank’s solution has worsened,with the corrosion rate rising from 0.037 to 0.069 mm/a following 300 min of annealing.展开更多
Turbine blades,due to their intricate geometry,are exposed to multiaxial stresses during operation.Consequently,it is imperative to examine the anisotropy of their stress-rupture behavior across various testing scenar...Turbine blades,due to their intricate geometry,are exposed to multiaxial stresses during operation.Consequently,it is imperative to examine the anisotropy of their stress-rupture behavior across various testing scenarios,particularly under high-temperature conditions.Stress-rupture behavior of a Ni-based single crystal superalloy was investigated under a load varying from 100 MPa to 137 MPa at 1,100℃ for both[001]-and[111]-orientated specimens.Results demonstrate that the rupture behavior of[111]-orientated specimens exhibits obviously higher sensitive to applied stress compared to[001]-orientated specimens.This difference is primarily attributed to the orientation dependentγ'coarsening behavior and distinct dislocation interactions atγ/γ'interfaces.In[001]-oriented specimens,plate-likeγ/γ'rafts rapidly form alongside well-developed interfacial dislocation networks,where theγ/γ'misfit stress dominates the microstructural evolution.In contrast,the[111]-orientated specimens exhibit retained,coarsenedγ'precipitates embedded within theγmatrix,accompanied by poorly developed interfacial dislocation networks.展开更多
To enhance the mechanical reliability of dental prostheses under long-term service conditions,this study aimed to evaluate the fracture behavior and energy dissipation characteristics of three commonly used prosthetic...To enhance the mechanical reliability of dental prostheses under long-term service conditions,this study aimed to evaluate the fracture behavior and energy dissipation characteristics of three commonly used prosthetic materials,namely,zirconia ceramics(ZrO_(2)),cobalt-chromium alloy(Co-Cr),and titanium-zirconium alloy(Ti-13Zr),under various crack configurations.A three-dimensional finite element model of a single-crown prosthesis incorporating predefined cracks was established,and both axial and oblique multidirectional loads were applied.Using LS-DYNA software,the deformation patterns,principal stress distribution,and energy release characteristics during crack propagation were systematically analyzed.The experimental results indicate that Ti-13Zr alloy exhibited the highest crack resistance,making it particularly suitable for patients with insufficient bone volume or limited implant space.Co-Cr alloy demonstrated favorable structural stability and mechanical performance under high-load conditions.In contrast,due to its inherent brittleness,ZrO_(2)was more prone to rapid fracture propagation in long-span or high-stress scenarios,although it remains a preferred option for anterior esthetic zones and patients with metal sensitivities.Furthermore,the simulation outcomes were theoretically validated using Griffith's energy-based fracture criterion,reinforcing the accuracy of failure predictions based on principal stress analysis.This study elucidates the differences in clinical applicability among prosthetic materials and reveals their distinct fracture mechanisms,thereby providing a theoretical foundation for optimizing material selection and structural design.The findings contribute to improving the long-term safety and functional stability of implant-supported dental restorations.展开更多
BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and of...BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and often the condition is prolonged,and the patients are prone to anxiety and uneasiness,which may be related to the harshness of the plateau environment,somatic discomfort due to the lack of oxygen,anxiety about the disease,and other factors.AIM To investigate the effects of cognitive behavioral therapy(CBT)on anxiety,sleep disorders,and hypoxia tolerance in patients with high-altitude respiratory diseases.METHODS A total of 2337 patients with high-altitude-related respiratory diseases treated at our hospital between November 2023 and January 2024 were selected as the study subjects.The subjects’pre-high-altitude residential altitude was approximately 1700 meters.They were divided into two groups.Both groups were given symptomatic treatment,and the control group implemented conventional nursing intervention,while the research group simultaneously conducted CBT intervention;assessed the degree of health knowledge of the two groups,and applied the Hamilton Anxiety Scale and the Pittsburgh Sleep Quality Index to assess the anxiety and sleep quality of the patients before and after the intervention,respectively.It also observed the length and efficiency of sleep,and detected the level of serum hypoxia inducible factor-1α,erythropoietin(EPO)and clinical intervention before and after intervention.EPO levels,and investigated satisfaction with the clinical intervention.RESULTS The rate of excellent health knowledge in the intervention group was 93.64%,which was higher than that in the control group(74.23%;P<0.05).Before the intervention,there was no significant difference in Hamilton Anxiety Scale and Pittsburgh Sleep Quality Index scores between the two groups(P>0.05),and after the intervention,the scores of the study group were significantly lower than those of the control group(P<0.05).There was no significant difference in sleep duration and sleep efficiency between the groups before the intervention(P>0.05),and after the intervention,the scores of the study group were significantly larger than those of the control group(P<0.05).There was no significant difference in serum hypoxia inducible factor-1αand EPO between the two groups before intervention(P>0.05),and both research groups were significantly lower than the control group after intervention(P<0.05).According to the questionnaire survey,the intervention satisfaction of the study group was 95.53%,which was higher than that of the control group(80.14%;P<0.05).CONCLUSION The CBT intervention in the treatment of patients with high-altitude-related respiratory diseases helps improve patients'health knowledge,relieve anxiety,improve sleep quality and hypoxia tolerance,and improve nursing satisfaction.展开更多
To address the challenge of low survival rates and limited data collection efficiency in current virtual probe deployments,which results from anomaly detection mechanisms in location-based service(LBS)applications,thi...To address the challenge of low survival rates and limited data collection efficiency in current virtual probe deployments,which results from anomaly detection mechanisms in location-based service(LBS)applications,this paper proposes a novel virtual probe deployment method based on user behavioral feature analysis.The core idea is to circumvent LBS anomaly detection by mimicking real-user behavior patterns.First,we design an automated data extraction algorithm that recognizes graphical user interface(GUI)elements to collect spatio-temporal behavior data.Then,by analyzing the automatically collected user data,we identify normal users’spatio-temporal patterns and extract their features such as high-activity time windows and spatial clustering characteristics.Subsequently,an antidetection scheduling strategy is developed,integrating spatial clustering optimization,load-balanced allocation,and time window control to generate probe scheduling schemes.Additionally,a self-correction mechanism based on an exponential backoff strategy is implemented to rectify anomalous behaviors andmaintain system stability.Experiments in real-world environments demonstrate that the proposed method significantly outperforms baseline methods in terms of both probe ban rate and task completion rate,while maintaining high time efficiency.This study provides a more reliable and clandestine solution for geosocial data collection and lays the foundation for building more robust virtual probe systems.展开更多
基金the National Natural Science Foundation of China (No.29875018) and the Natural Science Foundation of Gansu Province (ZS991-A25-
文摘The bicyclic cryptand 1,4,7, 10,13,16,21, 24-octaaza-bigcyclo [8, 8,8] hexacosan-3, 8, 12, 17, 20, 25-hex-one (COBH) bearing diaminoethane groups along the eight-atom bridges was synthesized. The structure consists of discrete neutral macrobicyclic units; the two cycles share the two tertiary amine nitrogen atoms, which exhibit an endo-cndo conformation. Three identical branches formed by 1, 2-diaminoethane link the two tertiary amine groups. The protonation reactions of cryptand (COBH) and its complex formation with copper (II) were investigated by potentiometry in water and in a DMSO/water (80:20 in mass ratio) mixture as solvents. The cryptand acts as a his-base through its two N-bridgehead and exhibits a strong cooperativity that favors the first protonation and makes the second one difficult (△pK= 5.0). An inward rotation of the amide groups to form hydrogen bonds accounts for this cooperativity. The interaction of COBH with copper (II) leads to several binuclear complex proton contents.
基金the National Natural Science Foundation of China(21978184)the“Jiangsu Innovation and Entrepreneurship(Shuang Chuang)Program”,the“Jiangsu Specially-Appointed Professors Program”the“Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions”.
文摘Up to now,how the secretion modes of intestinal fluid(i.e.,pancreaticobiliary secretion and wall secretion)can regulate intestinal acid-base environment has not been fully understood.Understanding the regulation mechanism is not only of great significance for intestinal health but may also lead to optimized designs for bio-inspired soft elastic reactors(SERs).In this work,the mixing and reaction of acidic gastric juice and alkaline intestinal fluid in a 3D duodenum with moving walls were modelled.A unique feature of this model is the implementation of both pancreaticobiliary and wall secretion of intestinal fluid as boundary conditions.This model allowed us to quantitatively explore the influence of secretion modes on pH regulation.The results demonstrated that coexistence of both pancreaticobiliary and wall secretions is the key to maintain the average pH in the duodenum at about 7.4.Their coexistence synergistically promotes the mixing and reaction of acid-base digestion liquids and provides a suitable catalytic environment for lipase in the intestine.
基金supported by the National Natural Science Foundation of China(No.22208376,No.UA22A20429)the Fundamental Research Funds for the Central Universities(buctrc202118,No.25CX07002A)+1 种基金the Qingdao New Energy Shandong Laboratory Open Project(QNESL OP 202303)the Shandong Provincial Natural Science Foundation(ZR2024QB175 and ZR2023LFG005)。
文摘Water management within the membrane electrode assemblies(MEAs)of electrochemical hydrogen compressors(EHCs)plays a crucial role in optimizing overall performance,particularly under low relative humidity(RH),where the anode side tends to dry out.Hollow mesoporous silica nanoparticles functionalized with amino groups(HMSNs-NH_(2))were integrated into the anode catalyst layers of EHCs to establish humidity-independent proton pathways through acid-base interactions with Nafion ionomers.These acid-base pairs between grafted–NH_(2)and sulfonic acid groups create continuous“proton highways”,enabling efficient conduction via the Grotthuss mechanism even at 50%RH.With only 2.5 wt%HMSNs-NH_(2)in the anode catalyst layer,hydrogen was compressed to 0.9 MPa in 60±3 s at 50%RH,representing a 55%reduction in compression time compared to MEAs with conventional Pt/C catalyst layers under the same conditions.This work overcomes the critical water-management bottleneck in EHCs,advancing the deployment of hydrogen energy technologies in arid environments.
基金financially supported by the National Natural Science Foundation of China(No.52377025)。
文摘The most widely used bisphenol A-type epoxy resin(DGEBA)in electrical engineering demonstrates excellent mechanical and electrical properties.However,the insoluble and infusible characteristics of cured DGEBA make it difficult to efficiently degrade and recycle decommissioned electrical equipment.In this study,a degradable itaconic acid-based epoxy resin incorporating dynamic covalent bonds was prepared through the integration of ester bonds and disulfide bonds,with itaconic acid as the precursor.The covalent bonding effects on the mechanical,thermal,electrical,and degradation characteristics were systematically evaluated.The experimental results revealed that the introduction of dynamic ester bonds enhanced the mechanical properties and thermal stability of the resin system,achieving a flexural strength of 141.57 MPa and an initial decomposition temperature T_(5%)of up to 344.9℃.The resin system containing dynamic disulfide bonds exhibited a dielectric breakdown strength of 41.11 k V/mm.Simultaneously,the incorporation of disulfide bonds endowed the epoxy resin with remarkable degradability,enabling complete dissolution within 1.5 h at 90℃ in a mixed solution of dithiothreitol(DTT)and N-methylpyrrolidone(NMP).This research provides a valuable reference for the application of itaconic acid-based vitrimer with dynamic covalent bonds in electrical materials,contributing to the development and utilization of environmentally friendly electrical equipment.
文摘Behavior recognition of Hu sheep contributes to their intensive and intelligent farming.Due to the generally high density of Hu sheep farming,severe occlusion occurs among different behaviors and even among sheep performing the same behavior,leading to missing and false detection issues in existing behavior recognition methods.A high-low frequency aggregated attention and negative sample comprehensive score loss and comprehensive score soft non-maximum suppression-YOLO(HLNC-YOLO)was proposed for identifying the behavior of Hu sheep,addressing the issues of missed and erroneous detections caused by occlusion between Hu sheep in intensive farming.Firstly,images of four typical behaviors-standing,lying,eating,and drinking-were collected from the sheep farm to construct the Hu sheep behavior dataset(HSBD).Next,to solve the occlusion issues,during the training phase,the C2F-HLAtt module was integrated,which combined high-low frequency aggregation attention,into the YOLO v8 Backbone to perceive occluded objects and introduce an auxiliary reversible branch to retain more effective features.Using comprehensive score regression loss(CSLoss)to reduce the scores of suboptimal boxes and enhance the comprehensive scores of occluded object boxes.Finally,the soft comprehensive score non-maximal suppression(Soft-CS-NMS)algorithm filtered prediction boxes during the inferencing.Testing on the HSBD,HLNC-YOLO achieved a mean average precision(mAP@50)of 87.8%,with a memory footprint of 17.4 MB.This represented an improvement of 7.1,2.2,4.6,and 11 percentage points over YOLO v8,YOLO v9,YOLO v10,and Faster R-CNN,respectively.Research indicated that the HLNC-YOLO accurately identified the behavior of Hu sheep in intensive farming and possessed generalization capabilities,providing technical support for smart farming.
文摘To investigate the influence of Al-Zn-Mg-Cu alloy with as-homogenized and as-rolled initial microstructures on the tensile flow behavior,isothermal tensile tests were conducted on a GLEEBLE-3500 isothermal simulator at temperatures of 380-440℃and strain rates of 0.05-1 s^(−1).The Johnson-Cook model,Hensel-Spittel model,strain-compensated Arrhenius model,and critical fracture strain model were established.Results show that through the evaluation of the models using the correlation coefficient(R)and the average absolute relative error,the strain-compensated Arrhenius model can represent the flow behavior of the alloy more accurately.Shear bands are more pronounced in the as-homogenized specimens,whereas dynamic recrystallization is predominantly observed in as-rolled specimens.Fracture morphology analysis reveals that a mixed fracture mechanism is prevalent in the as-homogenized specimen,whereas a ductile fracture mechanism is predominant in the as-rolled specimen.The processing maps indicate that the unstable region is reduced in the as-rolled specimens compared with that in the as-homogenized specimens.The optimal hot working windows for the as-homogenized and as-rolled specimens are determined as 410-440℃/0.14-1 s^(−1)and 380-400℃/0.05-0.29 s^(−1),respectively.
文摘Correction to:Nano-Micro Letters(2026)18:10.https://doi.org/10.1007/s40820-025-01852-8 Following publication of the original article[1],the authors reported that the last author’s name was inadvertently misspelled.The published version showed“Hongzhen Chen”,whereas the correct spelling should be“Hongzheng Chen”.The correct author name has been provided in this Correction,and the original article[1]has been corrected.
文摘Residential energy-use behavior and energy-saving awareness play a crucial role in sustainable urban energy planning and building energy efficiency,particularly under the pressures of climate change.However,existing studies often lack comparative analysis of urban-rural differences and tend to focus excessively on behavior patterns while neglecting the dimension of energysaving awareness.With China’s urbanization rate reaching 66.16%,understanding such regional disparities has become increasingly important.To address these research gaps,this study conducts a large-scale survey on space cooling behaviors among residents in Beijing,a representative Chinese megacity.It should be noted that living standards in such megacities are generally higher than the national average,which may shape distinctive energy-use profiles.Analyzing 1573valid samples(1064 urban/442 rural)in 2024,this study employed K-Prototypes and K-Modes clustering to identify typical cooling behavior and energy-saving awareness pattems,followed by Kendall/Chi-square correlation tests and XGBoost importance analysis to determine key influencing factors,with subsequent urban-rural comparative analysis.Results indicate that urban residents are primarily heat-sensitive or heat-tolerant,with a secondary patten of mid-low temperature preference,and generally exhibit long cooling durations;rural behavior is dominated by heat-tolerant type,followed by heat-sensitive,mid-low temperature preference,and never-on types as secondary patterns;both urban and rural areas exhibit energy-savingawareness characterized by low consumption-lowwillingness,though urban areas show marginally higher motivation;energy-saving awareness correlates with cooling behavior in rural areas,but this relationship weakens significantly in urban contexts.
基金TheNationalNatural Science Foundation ofChina(Nos.62272418,62102058)Zhejiang Provincial Natural Science Foundation Major Project(No.LD24F020004)the Major Open Project of Key Laboratory for Advanced Design and Intelligent Computing of the Ministry of Education(No.ADIC2023ZD001).
文摘With the rapid development of smart manufacturing,intelligent safety monitoring in industrial workshops has become increasingly important.To address the challenges of complex backgrounds,target scale variation,and excessive model parameters in worker violation detection,this study proposes ADCP-YOLO,an enhanced lightweight model based on YOLOv8.Here,“ADCP”represents four key improvements:Alterable Kernel Convolution(AKConv),Dilated-Wise Residual(DWR)module,Channel Reconstruction Global Attention Mechanism(CRGAM),and Powerful-IoU loss.These components collaboratively enhance feature extraction,multi-scale perception,and localization accuracy while effectively reducing model complexity and computational cost.Experimental results show that ADCP-YOLO achieves a mAP of 90.6%,surpassing YOLOv8 by 3.0%with a 6.6%reduction in parameters.These findings demonstrate that ADCP-YOLO successfully balances accuracy and efficiency,offering a practical solution for intelligent safety monitoring in smart factory workshops.
基金financially supported by the National Natural Science Foundation of China(Nos.52104319 and 52374323)。
文摘This study utilizes wet/dry cyclic corrosion testing combined with corrosion big data technology to investigate the mechanism by which chloride ions(Cl^(-))influence the corrosion behavior of 650 MPa high-strength low-alloy(HSLA)steel in industrially polluted environments.The corrosion process of 650 MPa HSLA steel occurred in two distinct stages:an initial corrosion stage and a stable corrosion stage.During the initial phase,the weight loss rate increased rapidly owing to the instability of the rust layer.Notably,this study demonstrated that 650 MPa HSLA steel exhibited superior corrosion resistance in Cl-containing environments.The formation of a corrosion-product film eventually reduced the weight-loss rate.However,the intrusion of Cl^(-)at increasing concentrations gradually destabilized theα/γ^(*)phases of the rust layer,leading to a looser structure and lower polarization resistance(R_(p)).The application of corrosion big data technology in this study facilitated the validation and analysis of the experimental results,offering new insights into the corrosion mechanisms of HSLA steel in chloride-rich environments.
基金supported in part by the National Key Research and Development Program of China(No.2023YFB4302903)the Fundamental Research Funds for the Central Universities(No.210525001464)。
文摘Flight behavior analysis provides the fundamental basis for the future development of air traffic management(ATM).The characteristics of aircraft behavior are inherently reflected in their flight trajectories,impacting flight efficiency and safety levels.However,existing research largely addresses inefficient or abnormal trajectories from a single perspective,with an absence of a unified evaluation standard.This paper introduces a method for analyzing flight deviation behavior based on automatic dependent surveillance-broadcast(ADS-B)data,defining novel metrics of trajectory redundancy and trajectory deviation.An adaptive detection algorithm is developed to capture diverse deviation patterns.Results reveal that higher trajectory redundancy is linked to lower operational efficiency,while trajectory deviation effectively identify stepped descents,holding patterns,detours,and other behaviors.The approach offers data-driven support for anomaly detection,performance evaluation and air traffic management,with substantial significance for civil aviation applications.
基金funded by the Natural Science Foundation of Hebei Province(C2025201032 to J.W.)High-Level Talents Research Start-Up Project of Hebei University(521100222044 to J.W.)+1 种基金the Huizhi Lead Innovation Space Project in High-tech Zone of Chengde City(HZLC202410 to L.M.)National Undergraduate Innovation and Entrepreneurship Training Program(202510098011 to H.Z.)。
文摘Urbanization destroys wildlife habitats,fragmenting them into small patches with poor connectivity,leading to population declines in species sensitive to such chan ges.Escape is the most common anti-predator strategy adopted by birds,refuges in habitats reduce or eliminate predation risk.Therefore,creating habitats with suitable refuges for birds has significant implications for their conservation.However,there have been few studies on refuge selection in birds.This study examined the Eurasian Tree Sparrow(Passer montanus)and Oriental Magpie(Pica serica)in urban and rural areas of Chengde City,northern China by measuring their alert distance(AD),flight initiation distance(FID),an d distance fled(DF)and analyzed their refuge selection characteristics after escaping.The FID/AD ratio was employed to assess the behavioral differences of birds in the risk trade-off.The results showed that the FID and FID/AD of both species were lower in urban areas than in rural areas and were negatively correlated with immediate human density.Sparrow FID was significantly affected by group size and landing substrate type.The FID of sparrows was positively correlated with the group size.The sparrows that fled to bushes escaped earlier.In urban and rural areas,sparrows exhibited significantly lower FID,DF,and FID/AD than magpies.The species adopted different refuge selection strategies,with magpies preferentially selecting trees with greater vertical height and sparrows selecting both trees and bushes.Further analysis indicated that the horizontal and vertical distances fled of both species were lower when fleeing to bushes.Urban planning and conservation areas construction should incorporate the ecological needs of local bird species to rationally configure their habitat structure,thereby optimizing the effect of avian conservation.
文摘High-performance magnesium alloys are in great demand to meet the lightweight design requirements of aircraft.Grain size has long been recognized as a key factor influencing the mechanical properties of alloys.This study investigates the effect of grain size,controlled by Zr addition,on the fatigue behavior of a recently developed low-cost Mg-2.6Nd-0.35Zn alloy,through systematic characterization and analysis of stress-life(S-N)curves,fatigue crack propagation,fracture surface morphology,stress intensity factor,and crack propagation threshold.The results show that after heat treatment(solution at 525±5℃ for 8 h and water quenching at 60-80℃,followed by aging at 250±5℃for 14 h and then air cooling),coarse-grained specimens(average grain size approximately 596μm)containing 0.12wt.%Zr exhibit greater resistance to fatigue crack propagation than fine-grained specimens(average grain size approximately 94μm)containing 0.46wt.%Zr.Coarse grains promote intergranular fracture,while fine grains favor transgranular fracture.In addition,coarse grains reduce the sensitivity of the crack tip to stress concentration.Furthermore,fine-grained samples demonstrate a longer total fatigue life,owing to their superior resistance to crack initiation,which significantly prolongs the crack initiation stage.These findings highlight the importance of optimizing grain size to achieve the best possible fatigue resistance in Mg-Nd-Zn-Zr alloys for practical engineering applications.
文摘BACKGROUND Despite societal guidelines recommending targeted screening for Barrett’s esophagus(BE)and esophageal adenocarcinoma(EAC)in individuals with gastroesophageal reflux symptoms(GERS),screening adherence is suboptimal.Current screening approaches fail to identify individuals not seeking medical consultation for GERS or whose GERS are managed with‘over-the-counter’(OTC)acid suppressant therapies.AIM To assess patients’self-management and help-seeking behavior for GERS.METHODS This cross-sectional study collected data from the Dutch general population aged 18-75 years between January and April 2023 using a web-based survey.The survey included questions regarding self-management(e.g.,use of acid suppressant therapy with or without prescription)and help-seeking behavior(e.g.,consulting a primary care provider)for GERS.Simple random sampling was performed to select individuals within the target age group.In total,18156 randomly selected individuals were invited to participate.The study protocol was registered in ClinicalTrials.gov(identifier:NCT05689918).RESULTS Of the 18156 invited individuals,3214 participants(17.7%)completed the survey,of which 1572 participants(48.9%)reported GERS.Of these,904 participants(57.5%)had never consulted a primary care provider for these symptoms,of which 331 participants(36.6%)reported taking OTC acid suppressant therapy in the past six months and 100 participants(11.1%)fulfilled the screening criteria for BE and EAC according to the European Society of Gastrointestinal Endoscopy Guideline.CONCLUSION The population fulfilling the screening criteria for BE and EAC is incompletely identified,suggesting potential underutilization of medical consultation.Raising public awareness of GERS as a risk factor for EAC is needed.
基金Supported by National Natural Science Foundation of China(Grant No.52275206).
文摘There is a strong coupling relationship between the friction characteristics of the ball-groove interface and the ball motion behavior.However,available studies tend to consider ball motion and frictional behavior separately.In this paper,a unified tribology-kinematic model is established considering the coupling effect between friction and the ball velocity vector.The friction in ball-groove contact and ball speed are simultaneously measured by a newly developed disc-ball-disc device for studying friction and movement in ball screws.A comprehensive analysis of rubbing interface behavior and ball motion is conducted.The results show that the coupling effect between friction in ball-groove contact and ball motion is quite obvious.The sliding velocity of the ball is much higher with coupling effect than that when ignoring coupling influence,especially at high-speed conditions.The friction in ball-groove contact decreases at first and then shows a dramatic increase with the gradual rise of rotation speed,which is caused by the coupling variation of sliding speed.The studies show that the disc-ball-disc approach is an innovative and valuable method to investigate friction and ball motion in ball screws.
基金supported by the National Natural Science Foundation of China(No.52271101)Suzhou Science and Technology Project,China(Nos.SYG202312,SJC2023005,SZS2023023)+1 种基金Nanjing Major Science and Technology Project,China(No.202309015)the Opening Project of Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology,China(No.ASMA202305)。
文摘To investigate the aging mechanisms and elucidate the correlations between unstable microstructure and performance in biodegradable Zn alloys,the accelerated aging experiment was conducted on a high-performance wrought Zn−0.1Mg alloy by annealing at 200℃ for varying durations.The findings reveal that the tensile strength of the alloy rapidly and significantly declines with prolonged annealing time,decreasing from 383 MPa for the as-received alloy to 102 MPa for the alloy subjected to 1440 min of annealing.The primary factors contributing to this considerable reduction in strength are static recrystallization,grain coarsening,and dislocation annihilation.Initially,the ductility of the alloy shows fluctuations,ultimately experiencing a marked decrease after extended annealing.This decline is linked to the grain growth and heightened texture intensity,while the unusual increase in ductility observed between 30 and 120 min of annealing is likely due to the formation of twins.In addition,due to rapid grain growth and an increase in precipitates and twins,the corrosion resistance of the alloy in Hank’s solution has worsened,with the corrosion rate rising from 0.037 to 0.069 mm/a following 300 min of annealing.
基金financially supported by the National Science and Technology Major Project of China(No.2019-VII-0019-0161 and No.2019-VII-0004-0144)the National Natural Science Foundation of China(No.92360302)the Shandong Provincial Natural Science Foundation of China(No.ZR2021QE103)。
文摘Turbine blades,due to their intricate geometry,are exposed to multiaxial stresses during operation.Consequently,it is imperative to examine the anisotropy of their stress-rupture behavior across various testing scenarios,particularly under high-temperature conditions.Stress-rupture behavior of a Ni-based single crystal superalloy was investigated under a load varying from 100 MPa to 137 MPa at 1,100℃ for both[001]-and[111]-orientated specimens.Results demonstrate that the rupture behavior of[111]-orientated specimens exhibits obviously higher sensitive to applied stress compared to[001]-orientated specimens.This difference is primarily attributed to the orientation dependentγ'coarsening behavior and distinct dislocation interactions atγ/γ'interfaces.In[001]-oriented specimens,plate-likeγ/γ'rafts rapidly form alongside well-developed interfacial dislocation networks,where theγ/γ'misfit stress dominates the microstructural evolution.In contrast,the[111]-orientated specimens exhibit retained,coarsenedγ'precipitates embedded within theγmatrix,accompanied by poorly developed interfacial dislocation networks.
基金Funded by the National Key R&D Program of China(No.2023YFC2412300)the Technology Development Project of Shan-dong Weigao Orthopedic Materials Co.,Ltd.(No.20221h0074)the Independent Innovation Research Fund of Wuhan University of Technology(No.104972024ZHZXhp0027)。
文摘To enhance the mechanical reliability of dental prostheses under long-term service conditions,this study aimed to evaluate the fracture behavior and energy dissipation characteristics of three commonly used prosthetic materials,namely,zirconia ceramics(ZrO_(2)),cobalt-chromium alloy(Co-Cr),and titanium-zirconium alloy(Ti-13Zr),under various crack configurations.A three-dimensional finite element model of a single-crown prosthesis incorporating predefined cracks was established,and both axial and oblique multidirectional loads were applied.Using LS-DYNA software,the deformation patterns,principal stress distribution,and energy release characteristics during crack propagation were systematically analyzed.The experimental results indicate that Ti-13Zr alloy exhibited the highest crack resistance,making it particularly suitable for patients with insufficient bone volume or limited implant space.Co-Cr alloy demonstrated favorable structural stability and mechanical performance under high-load conditions.In contrast,due to its inherent brittleness,ZrO_(2)was more prone to rapid fracture propagation in long-span or high-stress scenarios,although it remains a preferred option for anterior esthetic zones and patients with metal sensitivities.Furthermore,the simulation outcomes were theoretically validated using Griffith's energy-based fracture criterion,reinforcing the accuracy of failure predictions based on principal stress analysis.This study elucidates the differences in clinical applicability among prosthetic materials and reveals their distinct fracture mechanisms,thereby providing a theoretical foundation for optimizing material selection and structural design.The findings contribute to improving the long-term safety and functional stability of implant-supported dental restorations.
基金Supported by Army Logistics Department Health Bureau Project,No.QJGYXYJZX-012.
文摘BACKGROUND Due to the dry and cold climate,the obvious temperature difference between day and night,and the low oxygen content of the air in the plateau area,people are prone to upper respiratory tract diseases,and often the condition is prolonged,and the patients are prone to anxiety and uneasiness,which may be related to the harshness of the plateau environment,somatic discomfort due to the lack of oxygen,anxiety about the disease,and other factors.AIM To investigate the effects of cognitive behavioral therapy(CBT)on anxiety,sleep disorders,and hypoxia tolerance in patients with high-altitude respiratory diseases.METHODS A total of 2337 patients with high-altitude-related respiratory diseases treated at our hospital between November 2023 and January 2024 were selected as the study subjects.The subjects’pre-high-altitude residential altitude was approximately 1700 meters.They were divided into two groups.Both groups were given symptomatic treatment,and the control group implemented conventional nursing intervention,while the research group simultaneously conducted CBT intervention;assessed the degree of health knowledge of the two groups,and applied the Hamilton Anxiety Scale and the Pittsburgh Sleep Quality Index to assess the anxiety and sleep quality of the patients before and after the intervention,respectively.It also observed the length and efficiency of sleep,and detected the level of serum hypoxia inducible factor-1α,erythropoietin(EPO)and clinical intervention before and after intervention.EPO levels,and investigated satisfaction with the clinical intervention.RESULTS The rate of excellent health knowledge in the intervention group was 93.64%,which was higher than that in the control group(74.23%;P<0.05).Before the intervention,there was no significant difference in Hamilton Anxiety Scale and Pittsburgh Sleep Quality Index scores between the two groups(P>0.05),and after the intervention,the scores of the study group were significantly lower than those of the control group(P<0.05).There was no significant difference in sleep duration and sleep efficiency between the groups before the intervention(P>0.05),and after the intervention,the scores of the study group were significantly larger than those of the control group(P<0.05).There was no significant difference in serum hypoxia inducible factor-1αand EPO between the two groups before intervention(P>0.05),and both research groups were significantly lower than the control group after intervention(P<0.05).According to the questionnaire survey,the intervention satisfaction of the study group was 95.53%,which was higher than that of the control group(80.14%;P<0.05).CONCLUSION The CBT intervention in the treatment of patients with high-altitude-related respiratory diseases helps improve patients'health knowledge,relieve anxiety,improve sleep quality and hypoxia tolerance,and improve nursing satisfaction.
基金supported by theNationalNatural Science Foundation of China(No.U23A20305)National Key Research and Development Program of China(No.2022YFB3102900)+1 种基金Innovation Scientists and Technicians Troop Construction Projects of Henan Province,China(No.254000510007)Key Research and Development Project of Henan Province(No.221111321200).
文摘To address the challenge of low survival rates and limited data collection efficiency in current virtual probe deployments,which results from anomaly detection mechanisms in location-based service(LBS)applications,this paper proposes a novel virtual probe deployment method based on user behavioral feature analysis.The core idea is to circumvent LBS anomaly detection by mimicking real-user behavior patterns.First,we design an automated data extraction algorithm that recognizes graphical user interface(GUI)elements to collect spatio-temporal behavior data.Then,by analyzing the automatically collected user data,we identify normal users’spatio-temporal patterns and extract their features such as high-activity time windows and spatial clustering characteristics.Subsequently,an antidetection scheduling strategy is developed,integrating spatial clustering optimization,load-balanced allocation,and time window control to generate probe scheduling schemes.Additionally,a self-correction mechanism based on an exponential backoff strategy is implemented to rectify anomalous behaviors andmaintain system stability.Experiments in real-world environments demonstrate that the proposed method significantly outperforms baseline methods in terms of both probe ban rate and task completion rate,while maintaining high time efficiency.This study provides a more reliable and clandestine solution for geosocial data collection and lays the foundation for building more robust virtual probe systems.
