Objective:To systematically investigate the research status,research hotspots,and developmental trends of robotic techniques in stroke rehabilitation through bibliometric and visualization analysis.Methods:Literature ...Objective:To systematically investigate the research status,research hotspots,and developmental trends of robotic techniques in stroke rehabilitation through bibliometric and visualization analysis.Methods:Literature published in the Web of Science from 2004 to 2024 were screened.VOSviewer,CiteSpace,R Software,Microsoft Office Excel 2021,and“bibliometric.com”were employed to conduct bibliometric analysis and network visualization.Results:A total of 3,704 documents were retrieved.Northwestern University was the most productive institution.Krebs Hermano Igo was the most prolific author.The Journal of NeuroEngineering and Rehabilitation had the highest publication volume.The United States currently holds a leading position in various aspects,including the overall volume of publications,institutional contributions,author output,and funding support.Keywords such as“deep learning”“physical human-robot interaction”“wearable robotics”“mirror therapy”“telerehabilitation”“soft robotics”“augmented reality”“functional near-infrared spectroscopy,”and“impedance control”highlight the current research hotspots and frontiers.Conclusion:Rehabilitation robotics is a field with vigorous growth,progressively advancing toward intelligent,personalized,accessible,and efficient rehabilitation solutions with substantial future potential.展开更多
Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research o...Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research on Kawasaki disease in children,drawing from articles published in the CNKI and Web of Science core collection databases from January 1,2014,to January 1,2024.Key analysis components included authors,institutions,and keywords,supported by the creation of a corresponding knowledge map.Results:Literature Publications:Over the past decade,the analysis encompassed a total of 309 Chinese articles on nursing care for children with Kawasaki disease,with an average annual publication rate of 30.9 articles.Additionally,251 foreign language articles were scrutinized,exhibiting an average annual publication rate of 25.1 articles.Author and Institution Analysis:In Chinese literature,the notable figure of Huang Rimei emerged as a prolific author,with the Children's Hospital Affiliated with Zhengzhou University standing out as a high-yielding institution.Conversely,in English literature,the prolific authors Burns and Jane C were prominent,alongside the University of California,San Diego,which emerged as a high-yielding institution.Keyword and Research Hotspots Analysis:The focal points of research in Chinese literature revolved around continuous nursing,cardiovascular complications,clinical nursing pathways,rehabilitation effects,holistic nursing,and gamma globulin.Conversely,English literature emphasized research hotspots such as cardiovascular complications,treatment modalities,diagnostic approaches,long-term management strategies,gamma globulin therapy,steroid pulse therapy,and pediatric multisystem inflammatory syndrome.Conclusions:The quantity of Chinese literature concerning nursing care for children with Kawasaki disease appears comparatively scant,underscored by an uneven distribution of issuing institutions and a lack of influence.To address this,future endeavors should prioritize bolstering collaboration across diverse regions and institutions,conducting multi-center,cross-regional research,implementing clinical nursing pathways,and augmenting the continuity of care.Conversely,the upsurge in English literature publications regarding nursing care for children with Kawasaki disease signals a burgeoning interest,primarily concentrated on treatment modalities.This trend advocates for the integration of medical and nursing care and emphasizes the importance of remaining abreast of advancements in managing Kawasaki disease in children.展开更多
Objective:To analyze the current status,hotspot and trend of mental health research in patients with chronic kidney disease at home and abroad.Methods:China National Knowledge Infrastructure,WanFang,VIP,China Biology ...Objective:To analyze the current status,hotspot and trend of mental health research in patients with chronic kidney disease at home and abroad.Methods:China National Knowledge Infrastructure,WanFang,VIP,China Biology Medicine database,PubMed,and Web of Science core collection database were used as search sources from January 2004 to December 2024,and CiteSpace software was used for visual analysis and knowledge mapping.Results:A total of 2059 Chinese and 1678 foreign literatures were included.The number of publications showed a fluctuating upward trend,but the collaboration among authors was relatively loose.Negative psychology,such as depression and anxiety,as well as the quality of life of chronic kidney disease patients,were the main research hotspots.Conclusion:In the future,it is necessary to enhance cooperation and communication among researchers,continue to explore the mechanism of mental health,optimize research designs,innovate psychological nursing intervention measures,and focus on improving the psychological resilience and social support levels of patients.展开更多
Background:In recent years,the increase of pollen allergy encourages people to do a lot of research on the disease.This paper conducted a bibliometric study on pollen allergy,to explore the risk factors,as well as the...Background:In recent years,the increase of pollen allergy encourages people to do a lot of research on the disease.This paper conducted a bibliometric study on pollen allergy,to explore the risk factors,as well as the current status,hotspots and development trends,so as to provide reference for researchers in related fields.Method:The visual analysis method was used to analyze the related literature of pollen allergy-related based on CiteSpace(6.2.R4)software,which were searched in the database of Web of Science Core Collection(WoSCC)from 2005 to 24 February 2025.Results:Finally,5318 documents were included in this study.Results showed that the country with the most published articles is USA.The research institution with the most publications is Medical University of Vienna.The analysis demonstrates strong international research collaboration,with particularly intensive connections observed within Europe.Professor Valenta Rudolf from the Medical University of Vienna is the most prolific author.High frequency keywords in this field include“asthma”,“allergic rhinitis”,“children”,“sensitization”and“food allergy”.It is worth noting that the emerging terms up to 2025 include“allergen immunotherapy”,“air pollution”,“risk”,“allergenic pollen”,“airborne pollen”,“exposure”,and“climate change”.Allergy and the Journal of Allergy and Clinical Immunology(JACI)are the two most-cited journals,both exhibiting high impact factors and centrality.The review article by Bousquet J.(2018)published in Allergy has been cited 137 times,representing the most cited publication with a betweenness centrality of 0.17.The research focus in the field has shifted to using research methods based on protein and peptides and DNA vaccines for the prevention and treatment of immune reactions induced by tree pollen.The study of recombinant fragments of purified proteins with specific allergens for preventive treatment has broad application prospects.Conclusion:Its conclusion provides comprehensive and beneficial reference information for the prevention and treatment of pollen allergy.展开更多
Objective:To conduct a visual analysis of the current status and hotspots of adolescent obesity research based on CiteSpace,to provide evidence-based basis for research directions and ideas in this field.Methods:This ...Objective:To conduct a visual analysis of the current status and hotspots of adolescent obesity research based on CiteSpace,to provide evidence-based basis for research directions and ideas in this field.Methods:This study used subject words and free words to retrieve literature from China National Knowledge Infrastructure,Wanfang Database,and VIP Core database.The retrieval time was from January 1,2010 to December 31,2024.CiteSpace6.3.R2 software was used to perform cluster sub-visualization analysis of the number of articles,authors,and keywords of literature on adolescent obesity.Results:A total of 523 Chinese articles were included.Since 2010,the number of articles on adolescent obesity in China showed an increasing trend,with an average annual growth rate of 12.3%.From the perspective of spatial distribution,more regions,institutions,and researchers have begun to pay attention to the research in this field,exploring the impact of dietary imbalance and insufficient exercise on adolescent obesity in different regions and the management methods.From the perspective of cooperation,the cooperation of various regions and institutions showed the characteristics of regional concentration or professional concentration,mainly distributed in medicine and physical education.High-frequency keywords included“living standard”,“exercise intervention”,“physical activity”,“mental health”,“body fat rate”,and“body fat rate”.After 2020,“intelligent weight management platform”and“remote follow-up”emerged to reflect the deep integration of technology and health management.Keyword cluster analysis showed that research hotspots focused on the etiological mechanism of obesity,intervention models,regional characteristics in different regions,and the risk of obesity-related metabolic diseases.With the launch of the national“Weight Management Year”initiative,research has been tilted to community health promotion and multi-sectoral collaboration,focusing on obesity prevention of preschool children and AI-driven personalized intervention programs[1].However,there is a bottleneck of lack of tracking mechanisms for long-term effects such as adolescent development and metabolic adaptability.Conclusions:The research status and hotspots of adolescent obesity have gradually shifted from early etiological exploration to precise intervention models driven by technology empowerment.In the future,researchers can build an obesity prevention and control network covering the whole life cycle and the whole region through the three-dimensional drive of“technological innovation×policy empowerment×disciplinary integration”,and eventually achieve the goal of reducing the obesity rate in adolescents.展开更多
Objective:To explore the current status of sepsis-associated acute kidney injury(SA-AKI)research and predict its future research directions.Methods:The bibliometric overview of publications was conducted in the field ...Objective:To explore the current status of sepsis-associated acute kidney injury(SA-AKI)research and predict its future research directions.Methods:The bibliometric overview of publications was conducted in the field of SA-AKI based on Web of Science Core Collection database from January 2013 to August 2023.This study employed software such as CiteSpace and VOSviewer to conduct bibliometric and visualization analysis of the included literature,including publication trends,geographic distribution characteristics,author contributions,citations,funding sources characteristics,and keyword clustering.Results:A total of 6509 articles were analyzed,and the number of publications and citations increased from 2013 to 2022.The United States had the highest number of publications in SA-AKI,while France was the country with the highest number of citations per publication.Keyword clustering analysis showed that the pathophysiology and definition of SA-AKI were the research focus,and the research hotspots were"machine learning","vitamin C","kinase","hemodynamics","renal microcirculation"and"mitochondria".Literature coupling analysis indicated that exploring the management and treatment of SA-AKI was the research frontier.Conclusions:Over the past decade,SA-AKI research has shown a upward trend in terms of the number of publication.Research primarily focuses on exploring mechanisms and improving early warning systems.Mechanisms involve microcirculatory dysfunction,inflammation,and other pathophysiological factors.Future recommendations include continuing basic research,achieving clinical application of novel biomarkers,and prioritizing renal recovery mechanisms in treatment strategies.展开更多
Objective:To conduct a visual analysis of the current status and hotspots in the postoperative nursing of ureterocutaneostomy based on CiteSpace,in order to provide an evidence-based basis for the research direction a...Objective:To conduct a visual analysis of the current status and hotspots in the postoperative nursing of ureterocutaneostomy based on CiteSpace,in order to provide an evidence-based basis for the research direction and thinking in this field.Methods:In this study,the subject words and free words were used to search the China National Knowledge Infrastructure(CNKI),Wanfang Database,VIP Database,and Web of Science Core Database as the literature sources.The search time limit was from January 1,1999 to December 31,2024.CiteSpace 6.3.R2 software was used to conduct a visual analysis of the publication volume,authors,and keyword clusters of the literature related to ureterocutaneostomy nursing.Results:A total of 129 Chinese literary works were finally included.The results showed that 2019 was the peak year of publication volume(20 domestic articles);the First Affiliated Hospital of Nanchang University was the institution with the highest publication volume(13 articles);the high-frequency keywords included“bladder cancer”(42 times),“nursing”(29 times),and“quality of life”(16 times);the keyword cluster analysis showed that the research hotspots were concentrated in complication management,continuous nursing,and the application of intelligent technology.Conclusion:The nursing of ureterocutaneostomy has developed from a single technical operation to a multi-dimensional comprehensive intervention system,and the nursing shows a trend of multidisciplinary integration.In the future,it is necessary to strengthen the research and development of intelligent technology,the promotion of standardized nursing processes,and the balanced allocation of regional resources.展开更多
[Objectives]This study was conducted to perform visual analysis of the research hotspots and development trends of Cyperi Rhizoma in the field of antidepressant based on CiteSpace,so as to explore the application and ...[Objectives]This study was conducted to perform visual analysis of the research hotspots and development trends of Cyperi Rhizoma in the field of antidepressant based on CiteSpace,so as to explore the application and development direction of Cyperi Rhizoma in the field of antidepressant.[Methods]Highly-relevant literatures were selected from the core database of China National Knowledge Infrastructure(CNKI),and CiteSpace and WPS office software were employed to visually analyze relevant contents such as publishing institutions,scholars,keywords,publishing time,and citation frequency.[Results]A total of 297 domestic relevant literatures were selected.Most of the publications,institutions and authors were concentrated in universities,affiliated institutions and scientific research institutes of traditional Chinese medicine in China,and no relatively novel applied research direction has emerged.At present,the hot spots and frontiers of application were mostly concentrated in its role in treating depression,anxiety,gynecological diseases and other disorders.[Conclusions]The research on Cyperi Rhizoma for its antidepressant effects in China originated in the late 20 th century.From 2004 to 2024,studies have primarily focused on its pharmacological principles,mechanisms of action,and classification,while the exploration of its application in specific depressive disorders was limited.Overall,research progress has been relatively slow.Currently,further efforts are needed to optimize the active antidepressant components of Cyperi Rhizoma and clarify its mechanisms of action,which will facilitate its broader application in treating various stages of depressive disorders.展开更多
Based on the CiteSpace visualization knowledge graph,this article conducts a visual analysis of the evolution of publication volume,distribution of national institutions,keyword clustering,and other related literature...Based on the CiteSpace visualization knowledge graph,this article conducts a visual analysis of the evolution of publication volume,distribution of national institutions,keyword clustering,and other related literature on aging friendly bathroom facilities in 502 Chinese and English articles,in order to analyze the research status,hotspots,and future research directions in this field.Through analysis,it was found that research in this field is showing an increasing trend,but there is still a need for relevant experts to actively engage in cross institutional,cross disciplinary,and cross national exchanges and cooperation.Emerging concepts such as smart homes and informatization have become new research hotspots.Moreover,research trend has shifted from macro level discussions to specific optimizations,and has shown characteristics of disciplinary integration and technology driven development.Overall,this study has identified the development direction for improving the level of technological application,emphasizing the importance of interdisciplinary and international cooperation,and providing certain guidance for the construction of a research system for aging friendly bathroom facilities.展开更多
Objective To analyze the current research status and development trend of active surveillance of drug safety in China,and to provide reference and suggestions for future research.Methods Using bibliometric methods and...Objective To analyze the current research status and development trend of active surveillance of drug safety in China,and to provide reference and suggestions for future research.Methods Using bibliometric methods and with the help of the CiteSpace 6.1.R6,the literature on active surveillance of drug safety in CNKI from 2010 to 2022 was visualized and analyzed in terms of authors,institutions and keywords.Results and Conclusion The research on active surveillance of drug safety in China started late and is in a stable development period.Some Chinese scholars have done more work on active surveillance of drug safety.Additionally,a number of institutions have published some articles and surveillance objects,surveillance methods,and surveillance results are the main research content.However,the cross-institutional cooperation is not close.The traditional Chinese medicine injection,centralized surveillance,and automatic surveillance are the hot spots of research.It is the latest research frontier to use the Chinese hospital pharmacovigilance system to actively monitor drug safety.At present,the research related to active surveillance of drug safety in China is still in the early stage,and more in-depth research is needed to follow up.展开更多
AIM:To provide a comprehensive review of the advances in research on diabetes-associated dry eye(DADE),highlighting its pathophysiological mechanisms,risk factors,and demographic characteristics,laying the foundation ...AIM:To provide a comprehensive review of the advances in research on diabetes-associated dry eye(DADE),highlighting its pathophysiological mechanisms,risk factors,and demographic characteristics,laying the foundation for further investigation into its pathogenesis and treatment strategies.METHODS:A systemic review of the documents related to DADE had been performed based on the Web of Science database prior to achieving the plain text files of authors,titles,journals,and abstracts which afterwards had been imported into Citespace and VOSviewer software for data cleansing.The visual analysis was implemented from the following aspects:journals’publications,author and national cooperation,keyword co-occurrence,timeline analysis,and burst detection.RESULTS:The 318 documents in 167 journals had been incorporated with the overall annual citations and annual publications respectively growing significantly since 2014 and 2016.The keyword co-occurrence networks formed 4 clusters,with the representative keywords being dry eye,diabetes mellitus,prevalence,and diabetic retinopathy.Both the timeline map and the burst detection demonstrated that in the exploration of the pathogenesis of DADE,initial research was dedicated to Sjögren’s syndrome,followed by cross-sectional statistical analysis of the pertinent contributing factors of DADE using online databases.Precisely the oxidative stress seemed to surge into the research spotlight presently.The key pathogenic mechanisms of DADE include inflammation,oxidative stress and corneal neuropathy,contributing to the development of dry eye symptoms.CONCLUSION:Age,gender,diabetes duration,and diabetic retinopathy are strongly associated with the development of DADE,but the impact of other systemic factors require further investigation.With high prevalence of dry eye in Asia,valuable resources like the Korea National Health and Nutrition Examination Survey(KNHANES)database offer crucial data for developing risk prediction models for DADE.Building risk prediction models using machine learning algorithms is a promising future research direction,enabling physicians to identify high-risk individuals and implement early interventions.展开更多
Under the trend of economic globalization,the importance of supply chains has gradually become prominent,especially with the transformation and upgrading of China’s industrial chains in recent years.Supply chain tran...Under the trend of economic globalization,the importance of supply chains has gradually become prominent,especially with the transformation and upgrading of China’s industrial chains in recent years.Supply chain transformation has emerged as a significant focus of current academic research,and the construction of smart supply chains represents an inevitable development trend.This paper utilizes 1,051 research articles on smart supply chains published in core journals on China National Knowledge Infrastructure(CNKI)from 2014 to 2024 as the data source.It analyzes the literature data using CiteSpace software,visually exploring and revealing the frontiers and hotspots of domestic research on smart supply chains.The data analysis reveals that academic research in this field is at a stage of steady and healthy development.Domestic research trends include the cooperative mechanisms of smart supply chains in manufacturing,the operational mechanisms of smart supply chains in agriculture,and systematic research on influencing factors of smart supply chains.展开更多
In order to gain insight into the current research status and development trend of problem-based learning(PBL)in colleges and universities,this study employs the bibliometric method to conduct statistical and analytic...In order to gain insight into the current research status and development trend of problem-based learning(PBL)in colleges and universities,this study employs the bibliometric method to conduct statistical and analytical studies based on the examination of journal papers and review papers within the Web of Science(WOS)database.The objective is to provide a reference point for research in related fields.The findings indicate a sustained expansion in PBL research output at universities,with the United States accounting for most documents in the field,while European research institutions such as Aalborg University and Maastricht University are at the forefront.Nevertheless,the density of collaborative networks between authors is relatively low,and cross-institutional and interdisciplinary collaboration still requires further strengthening.The majority of research results are published in academic journals such as Academic Medicine and the International Journal of Sustainability in Higher Education.Presently,the focal point of PBL research in colleges and universities is undergoing a transition from a“single-discipline focus”to an“interdisciplinary integration.”This integration is profoundly intertwined with the nascent fields of modern educational technology and education for sustainable development,thereby offering a novel avenue for the advancement of pedagogical approaches and educational equity.展开更多
Background: Scar contractions caused by hand burns seriously impact both the function and appearance of the hand.Consequently,post-burn hand reconstruction is a primary focus of secondary reconstructive surgery perfor...Background: Scar contractions caused by hand burns seriously impact both the function and appearance of the hand.Consequently,post-burn hand reconstruction is a primary focus of secondary reconstructive surgery performed within the first 10 years after a burn injury.This study aimed to identify developmental trends and research hotspots in post-burn hand reconstruction,providing insights and recommendations for researchers.Methods: Bibliometric and visualization analyses were conducted using Cite Space v6.4.R1(64-bit) and VOS viewer.The Web of Science Core Collection served as the data source.A total of 136 articles between 1997 and2025 were included based on the following keywords: “postburn hand reconstruction” or “postburn hand” or“scar contraction hand deformity.”Results: The field of post-burn hand reconstruction is advancing,as indicated by the overall and annual increase in publications.The United States leads in number of published papers.However,major institutions show low centrality,indicating weak collaboration between countries and regions,with research still dominated by singlecenter studies.The top three most prolific authors were Paul P M van Zuijlen,Fatih Uyghur,and Ersin Uyghur.The keywords “double Z-plasty” and the cluster “flap” not only have high emergence intensity but also appear frequently in recent studies,marking them as current research hotspots.Conclusion: The lack of long-term research and consensus limits further advancements in post-burn hand reconstruction.To address this,multi-center and multi-disciplinary collaborations should be encouraged.Additionally,integrating basic medical research with biomedical engineering could enhance the management and outcomes of post-burn hand reconstruction.展开更多
AIM:To gain insight into the future research directions in scleral contact lenses(SCLs)through a comprehensive bibliometrics study.METHODS:The publications related to SCLs were screened from the Web of Science Core Co...AIM:To gain insight into the future research directions in scleral contact lenses(SCLs)through a comprehensive bibliometrics study.METHODS:The publications related to SCLs were screened from the Web of Science Core Collection(WOSCC)database.All bibliographic information was extracted and used to conduct a performance analysis.CiteSpace and VOSviewer were employed to visualize annual publication counts,journals,authors,countries,institutions,collaboration networks,keywords,and references.RESULTS:A total of 498 articles were included in our analysis and the number of publications about SCLs showed a significant yearly increase.These publications predominantly emanated from 523 institutions across 38 countries,with the United States and Australia leading in frequency.Totally 1361 authors were identified,among whom Vincent J.Stephen exhibited the highest number of publications,while Jacobs S.Deborah received the most citations.Notably,the journal Contact Lens&Anterior Eye emerged as the primary publisher of studies,and it also boasted the highest citation rate.“Fluid-ventilated,gas-permeable scleral contact lens is an effective option for managing severe ocular surface disease and many corneal disorders that would otherwise require penetrating keratoplasty”was the most cited paper published in eye&contact lens in 2005.The most prevalent keywords encompassed“keratoconus”,“scleral contact lenses”,“management”,“contact lenses”,“scleral contact lens”,“ocular surface disease”,“dry eye”,and“contact lens”.CONCLUSION:Although SCLs have demonstrated significant potential in ophthalmological care,the results offer valuable insights pertinent to future research directions and clinical practice.Greater emphasis should be placed on developing enhancements in design,materials,and fitting technique,as well as on reducing the complications associated with SCLs.展开更多
Stem cells have been confirmed to be involved in the occurrence and development of diabetic retinopathy;however,the underlying mechanisms remain unclear.In this study,we used Citespace software to visually analyze 552...Stem cells have been confirmed to be involved in the occurrence and development of diabetic retinopathy;however,the underlying mechanisms remain unclear.In this study,we used Citespace software to visually analyze 552 articles exploring the stem cell-based treatment of diabetic retinopathy over the past 20 years,which were included in the Web of Science Core Collection.We found the following:(1)a co-citation analysis of the references cited by all 552 articles indicated 15 clusters.In cluster#0,representing the stem cell field,some highly cited landmark studies emerged between 2009–2013.For example,endothelial progenitor cells and diabetic retinopathy gradually received the full attention of scholars,in terms of their relationship and therapeutic prospects.Some researchers also verified the potential of adipose-derived stem cells to differentiate into stable retinal perivascular cells,using a variety of animal models of retinal vascular disease.All of these achievements provided references for the subsequent stem cell research.(2)An analysis of popular keywords among the 552 articles revealed that,during the past 20 years,a relative increase in basic research articles examining stem cells and endothelial progenitor cells for the treatment of diabetic retinopathy was observed.The contents of these articles primarily involved the expression of vascular endothelial growth factor,vascular regeneration,oxidative stress,and inflammatory response.(3)A burst analysis of keywords used in the 552 articles indicated that genetic and cytological research regarding the promotion of angiogenesis was an issue of concern from 2001 to 2012,including several studies addressing the expression of various growth factor genes;from 2014 to 2020,mouse models of diabetic retinopathy were recognized as mature animal models,and the most recent research has focused on macular degeneration,macular edema,neurodegeneration,and inflammatory changes in diabetic animal models.(4)Globally,the current authoritative studies have focused on basic research towards the stem cell treatment of diabetic retinopathy.Existing clinical studies are of low quality and have insufficient evidence levels,and their findings have not yet been widely accepted in clinical practice.Major challenges during stem cell transplantation remain,including stem cell heterogeneity,cell delivery,and the effective homing of stem cells to damaged tissue.However,clinical trials examining potential stem cell-based treatments of diabetic retinopathy,including the use of pluripotent stem cells,retinal pigment epithelial cells,bone marrow mesenchymal stem cells,and endothelial progenitor cells,are currently ongoing,and high-quality clinical evidence is likely to appear in the future,to promote clinical transformation.展开更多
Neurogenic bladder is a dysfunction of the lower urinary tract caused by nervous system disor- der. We investigated the trends in publication of articles under the topic ＂neurogenic bladder＂ using bibliometric analy...Neurogenic bladder is a dysfunction of the lower urinary tract caused by nervous system disor- der. We investigated the trends in publication of articles under the topic ＂neurogenic bladder＂ using bibliometric analysis. Articles on neurogenic bladder, published between 1995 and 2014, were retrieved from the ISI Web of Science citation database. We analyzed the search results for authors, countries, institutions, journals, and top-cited papers. A total of 1,904 articles were re- trieved. There was a small increase in the number of articles on neurogenic bladder from 1995 （n = 43） to 2014 （n = 117）. The USA was the leading country in the total number of articles （n = 598）. However, the number of publications from China has rapidly increased, and China was ranked second in 2014. Emmanuel Chartier-Kastler （n = 65） was the most productive author, and University of Paris VI （Paris 6） （n = 61） was the most productive institution. The Journal of Urology published the greatest number of artides on this topic （n = 285）. Articles on neurogenic bladder were often published in a professional journal under the category Urology ＆ Nephrology, Neurosciences ＆ Neurology, or Rehabilitation. Visualization analysis based on co-citation networks was conducted using CiteSpace III. Visualization analysis revealed that the hot spots in neurogenic bladder were botulinum toxin-A, prazosin, bethanechol, and afferent pathways. These findings provide new insight into the publication trends and hot spots in neurogenic bladder.展开更多
Objective:The objective of this study is to explore the current situation,clinical research hot spots,and trends of traditional Chinese medicine(TCM)nursing technology in rheumatoid arthritis(RA),to draw a panorama of...Objective:The objective of this study is to explore the current situation,clinical research hot spots,and trends of traditional Chinese medicine(TCM)nursing technology in rheumatoid arthritis(RA),to draw a panorama of clinical research,to provide the basis and clues for subsequent high-level evidence integration and further in-depth research.Materials and Methods:Seven databases including China National Knowledge Infrastructure,Chinese Scientific Journal Database(VIP),Wanfang Database,Chinese Biomedical Literature Database(Sino-Med),PubMed,Embase,and the Cochrane Library were searched.The bibliometric method and visualization software CiteSpace were used to conduct a multi-dimensional analysis of the included literature.Results:A total of 805 pieces of literature were included(of them,one was written in German and four in English),and the number of published literature showed an increasing trend year by year.There were only 30(3.73%)pieces of literature published in nursing journals.The hot spots of the co-occurrence map were concentrated in:(1)the nursing of fumigation in RA;(2)the efficacy evaluation of TCM nursing technology on pain,joint malformation,and joint dysfunction caused by RA.The included literature themes focused on five TCM technologies:fumigation,moxibustion,acupoint patching,acupoint injection,and Chinese herbal soaking.The beginning year and strength in TCM fumigation were 2012 and 5.2,and those in moxibustion were 2011 and 3.38.Conclusion:The related studies are on the rise.It has entered the field of international readers with clear research hot spots.However,there are still shortcomings such as little literature published in Chinese nursing core journals,few non-Chinese-related documents,and a lack of international exchanges and cooperation.The current research hot spots in this field are TCM fumigation,and the cutting-edge trend of future research may be fumigation and moxibustion technology.It is suggested that further research can focus on evidence integration and original research on the self-optimization of these two techniques.展开更多
[Objectives]Based on the related literature of benefit finding in China National Knowledge Infrastructure(CNKI),this paper analyzes the research status,hot spots and trends in this field.[Methods]To search for the rel...[Objectives]Based on the related literature of benefit finding in China National Knowledge Infrastructure(CNKI),this paper analyzes the research status,hot spots and trends in this field.[Methods]To search for the related literature on benefit finding in China National Knowledge Infrastructure(CNKI),and use Citespace software to visually analyze the number of papers,authors,institutions and keywords.[Results]A total of 204 related papers were obtained,and the annual number of published papers showed a gradual increasing trend.The authors of published papers were represented by Zhang Fenglan,Liu Zhunzhun and Zhang Ting,and the Nursing College of Anhui Medical University published the most papers.The research focus was on social support,coping method and other influencing factors,and qualitative research was the main research type.The key population was breast cancer,stroke patients and their caregivers,and the development trend focused on reliability and validity test and correlation analysis.[Conclusions]The field of benefit finding in China is in the initial exploration stage,and there is little cooperation and exchange between authors and institutions.In the future,academic exchanges and multidisciplinary assistance should be strengthened to promote the rapid development of this field.展开更多
文摘Objective:To systematically investigate the research status,research hotspots,and developmental trends of robotic techniques in stroke rehabilitation through bibliometric and visualization analysis.Methods:Literature published in the Web of Science from 2004 to 2024 were screened.VOSviewer,CiteSpace,R Software,Microsoft Office Excel 2021,and“bibliometric.com”were employed to conduct bibliometric analysis and network visualization.Results:A total of 3,704 documents were retrieved.Northwestern University was the most productive institution.Krebs Hermano Igo was the most prolific author.The Journal of NeuroEngineering and Rehabilitation had the highest publication volume.The United States currently holds a leading position in various aspects,including the overall volume of publications,institutional contributions,author output,and funding support.Keywords such as“deep learning”“physical human-robot interaction”“wearable robotics”“mirror therapy”“telerehabilitation”“soft robotics”“augmented reality”“functional near-infrared spectroscopy,”and“impedance control”highlight the current research hotspots and frontiers.Conclusion:Rehabilitation robotics is a field with vigorous growth,progressively advancing toward intelligent,personalized,accessible,and efficient rehabilitation solutions with substantial future potential.
基金Kunming Health Science and Technology Talent Cultivation Project(Project No.:2023-Cultivation Category-00)Health Research Project of Kunming Municipal Health Commission(Project No.:2022-14-04-006)。
文摘Objective:This study aims to analyze the research hotspots and trends in nursing care for children with Kawasaki disease.Methods:The study utilized the CiteSpace 6.1.R6 software to visualize nursing-related research on Kawasaki disease in children,drawing from articles published in the CNKI and Web of Science core collection databases from January 1,2014,to January 1,2024.Key analysis components included authors,institutions,and keywords,supported by the creation of a corresponding knowledge map.Results:Literature Publications:Over the past decade,the analysis encompassed a total of 309 Chinese articles on nursing care for children with Kawasaki disease,with an average annual publication rate of 30.9 articles.Additionally,251 foreign language articles were scrutinized,exhibiting an average annual publication rate of 25.1 articles.Author and Institution Analysis:In Chinese literature,the notable figure of Huang Rimei emerged as a prolific author,with the Children's Hospital Affiliated with Zhengzhou University standing out as a high-yielding institution.Conversely,in English literature,the prolific authors Burns and Jane C were prominent,alongside the University of California,San Diego,which emerged as a high-yielding institution.Keyword and Research Hotspots Analysis:The focal points of research in Chinese literature revolved around continuous nursing,cardiovascular complications,clinical nursing pathways,rehabilitation effects,holistic nursing,and gamma globulin.Conversely,English literature emphasized research hotspots such as cardiovascular complications,treatment modalities,diagnostic approaches,long-term management strategies,gamma globulin therapy,steroid pulse therapy,and pediatric multisystem inflammatory syndrome.Conclusions:The quantity of Chinese literature concerning nursing care for children with Kawasaki disease appears comparatively scant,underscored by an uneven distribution of issuing institutions and a lack of influence.To address this,future endeavors should prioritize bolstering collaboration across diverse regions and institutions,conducting multi-center,cross-regional research,implementing clinical nursing pathways,and augmenting the continuity of care.Conversely,the upsurge in English literature publications regarding nursing care for children with Kawasaki disease signals a burgeoning interest,primarily concentrated on treatment modalities.This trend advocates for the integration of medical and nursing care and emphasizes the importance of remaining abreast of advancements in managing Kawasaki disease in children.
基金Tianjin Medical Key Discipline Construction Project(Project No.:TJYXZDXK-071C)。
文摘Objective:To analyze the current status,hotspot and trend of mental health research in patients with chronic kidney disease at home and abroad.Methods:China National Knowledge Infrastructure,WanFang,VIP,China Biology Medicine database,PubMed,and Web of Science core collection database were used as search sources from January 2004 to December 2024,and CiteSpace software was used for visual analysis and knowledge mapping.Results:A total of 2059 Chinese and 1678 foreign literatures were included.The number of publications showed a fluctuating upward trend,but the collaboration among authors was relatively loose.Negative psychology,such as depression and anxiety,as well as the quality of life of chronic kidney disease patients,were the main research hotspots.Conclusion:In the future,it is necessary to enhance cooperation and communication among researchers,continue to explore the mechanism of mental health,optimize research designs,innovate psychological nursing intervention measures,and focus on improving the psychological resilience and social support levels of patients.
文摘Background:In recent years,the increase of pollen allergy encourages people to do a lot of research on the disease.This paper conducted a bibliometric study on pollen allergy,to explore the risk factors,as well as the current status,hotspots and development trends,so as to provide reference for researchers in related fields.Method:The visual analysis method was used to analyze the related literature of pollen allergy-related based on CiteSpace(6.2.R4)software,which were searched in the database of Web of Science Core Collection(WoSCC)from 2005 to 24 February 2025.Results:Finally,5318 documents were included in this study.Results showed that the country with the most published articles is USA.The research institution with the most publications is Medical University of Vienna.The analysis demonstrates strong international research collaboration,with particularly intensive connections observed within Europe.Professor Valenta Rudolf from the Medical University of Vienna is the most prolific author.High frequency keywords in this field include“asthma”,“allergic rhinitis”,“children”,“sensitization”and“food allergy”.It is worth noting that the emerging terms up to 2025 include“allergen immunotherapy”,“air pollution”,“risk”,“allergenic pollen”,“airborne pollen”,“exposure”,and“climate change”.Allergy and the Journal of Allergy and Clinical Immunology(JACI)are the two most-cited journals,both exhibiting high impact factors and centrality.The review article by Bousquet J.(2018)published in Allergy has been cited 137 times,representing the most cited publication with a betweenness centrality of 0.17.The research focus in the field has shifted to using research methods based on protein and peptides and DNA vaccines for the prevention and treatment of immune reactions induced by tree pollen.The study of recombinant fragments of purified proteins with specific allergens for preventive treatment has broad application prospects.Conclusion:Its conclusion provides comprehensive and beneficial reference information for the prevention and treatment of pollen allergy.
文摘Objective:To conduct a visual analysis of the current status and hotspots of adolescent obesity research based on CiteSpace,to provide evidence-based basis for research directions and ideas in this field.Methods:This study used subject words and free words to retrieve literature from China National Knowledge Infrastructure,Wanfang Database,and VIP Core database.The retrieval time was from January 1,2010 to December 31,2024.CiteSpace6.3.R2 software was used to perform cluster sub-visualization analysis of the number of articles,authors,and keywords of literature on adolescent obesity.Results:A total of 523 Chinese articles were included.Since 2010,the number of articles on adolescent obesity in China showed an increasing trend,with an average annual growth rate of 12.3%.From the perspective of spatial distribution,more regions,institutions,and researchers have begun to pay attention to the research in this field,exploring the impact of dietary imbalance and insufficient exercise on adolescent obesity in different regions and the management methods.From the perspective of cooperation,the cooperation of various regions and institutions showed the characteristics of regional concentration or professional concentration,mainly distributed in medicine and physical education.High-frequency keywords included“living standard”,“exercise intervention”,“physical activity”,“mental health”,“body fat rate”,and“body fat rate”.After 2020,“intelligent weight management platform”and“remote follow-up”emerged to reflect the deep integration of technology and health management.Keyword cluster analysis showed that research hotspots focused on the etiological mechanism of obesity,intervention models,regional characteristics in different regions,and the risk of obesity-related metabolic diseases.With the launch of the national“Weight Management Year”initiative,research has been tilted to community health promotion and multi-sectoral collaboration,focusing on obesity prevention of preschool children and AI-driven personalized intervention programs[1].However,there is a bottleneck of lack of tracking mechanisms for long-term effects such as adolescent development and metabolic adaptability.Conclusions:The research status and hotspots of adolescent obesity have gradually shifted from early etiological exploration to precise intervention models driven by technology empowerment.In the future,researchers can build an obesity prevention and control network covering the whole life cycle and the whole region through the three-dimensional drive of“technological innovation×policy empowerment×disciplinary integration”,and eventually achieve the goal of reducing the obesity rate in adolescents.
文摘Objective:To explore the current status of sepsis-associated acute kidney injury(SA-AKI)research and predict its future research directions.Methods:The bibliometric overview of publications was conducted in the field of SA-AKI based on Web of Science Core Collection database from January 2013 to August 2023.This study employed software such as CiteSpace and VOSviewer to conduct bibliometric and visualization analysis of the included literature,including publication trends,geographic distribution characteristics,author contributions,citations,funding sources characteristics,and keyword clustering.Results:A total of 6509 articles were analyzed,and the number of publications and citations increased from 2013 to 2022.The United States had the highest number of publications in SA-AKI,while France was the country with the highest number of citations per publication.Keyword clustering analysis showed that the pathophysiology and definition of SA-AKI were the research focus,and the research hotspots were"machine learning","vitamin C","kinase","hemodynamics","renal microcirculation"and"mitochondria".Literature coupling analysis indicated that exploring the management and treatment of SA-AKI was the research frontier.Conclusions:Over the past decade,SA-AKI research has shown a upward trend in terms of the number of publication.Research primarily focuses on exploring mechanisms and improving early warning systems.Mechanisms involve microcirculatory dysfunction,inflammation,and other pathophysiological factors.Future recommendations include continuing basic research,achieving clinical application of novel biomarkers,and prioritizing renal recovery mechanisms in treatment strategies.
基金Research Project of the First Affiliated Hospital of Shihezi University(HL202102)。
文摘Objective:To conduct a visual analysis of the current status and hotspots in the postoperative nursing of ureterocutaneostomy based on CiteSpace,in order to provide an evidence-based basis for the research direction and thinking in this field.Methods:In this study,the subject words and free words were used to search the China National Knowledge Infrastructure(CNKI),Wanfang Database,VIP Database,and Web of Science Core Database as the literature sources.The search time limit was from January 1,1999 to December 31,2024.CiteSpace 6.3.R2 software was used to conduct a visual analysis of the publication volume,authors,and keyword clusters of the literature related to ureterocutaneostomy nursing.Results:A total of 129 Chinese literary works were finally included.The results showed that 2019 was the peak year of publication volume(20 domestic articles);the First Affiliated Hospital of Nanchang University was the institution with the highest publication volume(13 articles);the high-frequency keywords included“bladder cancer”(42 times),“nursing”(29 times),and“quality of life”(16 times);the keyword cluster analysis showed that the research hotspots were concentrated in complication management,continuous nursing,and the application of intelligent technology.Conclusion:The nursing of ureterocutaneostomy has developed from a single technical operation to a multi-dimensional comprehensive intervention system,and the nursing shows a trend of multidisciplinary integration.In the future,it is necessary to strengthen the research and development of intelligent technology,the promotion of standardized nursing processes,and the balanced allocation of regional resources.
基金Supported by Undergraduate Innovation and Enterpreneurship Training Program of Guangxi(S202310600067)Guangxi First-class Discipline Construction Project(GJKY[2022]1).
文摘[Objectives]This study was conducted to perform visual analysis of the research hotspots and development trends of Cyperi Rhizoma in the field of antidepressant based on CiteSpace,so as to explore the application and development direction of Cyperi Rhizoma in the field of antidepressant.[Methods]Highly-relevant literatures were selected from the core database of China National Knowledge Infrastructure(CNKI),and CiteSpace and WPS office software were employed to visually analyze relevant contents such as publishing institutions,scholars,keywords,publishing time,and citation frequency.[Results]A total of 297 domestic relevant literatures were selected.Most of the publications,institutions and authors were concentrated in universities,affiliated institutions and scientific research institutes of traditional Chinese medicine in China,and no relatively novel applied research direction has emerged.At present,the hot spots and frontiers of application were mostly concentrated in its role in treating depression,anxiety,gynecological diseases and other disorders.[Conclusions]The research on Cyperi Rhizoma for its antidepressant effects in China originated in the late 20 th century.From 2004 to 2024,studies have primarily focused on its pharmacological principles,mechanisms of action,and classification,while the exploration of its application in specific depressive disorders was limited.Overall,research progress has been relatively slow.Currently,further efforts are needed to optimize the active antidepressant components of Cyperi Rhizoma and clarify its mechanisms of action,which will facilitate its broader application in treating various stages of depressive disorders.
文摘Based on the CiteSpace visualization knowledge graph,this article conducts a visual analysis of the evolution of publication volume,distribution of national institutions,keyword clustering,and other related literature on aging friendly bathroom facilities in 502 Chinese and English articles,in order to analyze the research status,hotspots,and future research directions in this field.Through analysis,it was found that research in this field is showing an increasing trend,but there is still a need for relevant experts to actively engage in cross institutional,cross disciplinary,and cross national exchanges and cooperation.Emerging concepts such as smart homes and informatization have become new research hotspots.Moreover,research trend has shifted from macro level discussions to specific optimizations,and has shown characteristics of disciplinary integration and technology driven development.Overall,this study has identified the development direction for improving the level of technological application,emphasizing the importance of interdisciplinary and international cooperation,and providing certain guidance for the construction of a research system for aging friendly bathroom facilities.
文摘Objective To analyze the current research status and development trend of active surveillance of drug safety in China,and to provide reference and suggestions for future research.Methods Using bibliometric methods and with the help of the CiteSpace 6.1.R6,the literature on active surveillance of drug safety in CNKI from 2010 to 2022 was visualized and analyzed in terms of authors,institutions and keywords.Results and Conclusion The research on active surveillance of drug safety in China started late and is in a stable development period.Some Chinese scholars have done more work on active surveillance of drug safety.Additionally,a number of institutions have published some articles and surveillance objects,surveillance methods,and surveillance results are the main research content.However,the cross-institutional cooperation is not close.The traditional Chinese medicine injection,centralized surveillance,and automatic surveillance are the hot spots of research.It is the latest research frontier to use the Chinese hospital pharmacovigilance system to actively monitor drug safety.At present,the research related to active surveillance of drug safety in China is still in the early stage,and more in-depth research is needed to follow up.
基金Supported by the Exploratory Project of The Second Affiliated Hospital of Xi’an Jiaotong University[No.2020YJ(ZYTS)154].
文摘AIM:To provide a comprehensive review of the advances in research on diabetes-associated dry eye(DADE),highlighting its pathophysiological mechanisms,risk factors,and demographic characteristics,laying the foundation for further investigation into its pathogenesis and treatment strategies.METHODS:A systemic review of the documents related to DADE had been performed based on the Web of Science database prior to achieving the plain text files of authors,titles,journals,and abstracts which afterwards had been imported into Citespace and VOSviewer software for data cleansing.The visual analysis was implemented from the following aspects:journals’publications,author and national cooperation,keyword co-occurrence,timeline analysis,and burst detection.RESULTS:The 318 documents in 167 journals had been incorporated with the overall annual citations and annual publications respectively growing significantly since 2014 and 2016.The keyword co-occurrence networks formed 4 clusters,with the representative keywords being dry eye,diabetes mellitus,prevalence,and diabetic retinopathy.Both the timeline map and the burst detection demonstrated that in the exploration of the pathogenesis of DADE,initial research was dedicated to Sjögren’s syndrome,followed by cross-sectional statistical analysis of the pertinent contributing factors of DADE using online databases.Precisely the oxidative stress seemed to surge into the research spotlight presently.The key pathogenic mechanisms of DADE include inflammation,oxidative stress and corneal neuropathy,contributing to the development of dry eye symptoms.CONCLUSION:Age,gender,diabetes duration,and diabetic retinopathy are strongly associated with the development of DADE,but the impact of other systemic factors require further investigation.With high prevalence of dry eye in Asia,valuable resources like the Korea National Health and Nutrition Examination Survey(KNHANES)database offer crucial data for developing risk prediction models for DADE.Building risk prediction models using machine learning algorithms is a promising future research direction,enabling physicians to identify high-risk individuals and implement early interventions.
文摘Under the trend of economic globalization,the importance of supply chains has gradually become prominent,especially with the transformation and upgrading of China’s industrial chains in recent years.Supply chain transformation has emerged as a significant focus of current academic research,and the construction of smart supply chains represents an inevitable development trend.This paper utilizes 1,051 research articles on smart supply chains published in core journals on China National Knowledge Infrastructure(CNKI)from 2014 to 2024 as the data source.It analyzes the literature data using CiteSpace software,visually exploring and revealing the frontiers and hotspots of domestic research on smart supply chains.The data analysis reveals that academic research in this field is at a stage of steady and healthy development.Domestic research trends include the cooperative mechanisms of smart supply chains in manufacturing,the operational mechanisms of smart supply chains in agriculture,and systematic research on influencing factors of smart supply chains.
文摘In order to gain insight into the current research status and development trend of problem-based learning(PBL)in colleges and universities,this study employs the bibliometric method to conduct statistical and analytical studies based on the examination of journal papers and review papers within the Web of Science(WOS)database.The objective is to provide a reference point for research in related fields.The findings indicate a sustained expansion in PBL research output at universities,with the United States accounting for most documents in the field,while European research institutions such as Aalborg University and Maastricht University are at the forefront.Nevertheless,the density of collaborative networks between authors is relatively low,and cross-institutional and interdisciplinary collaboration still requires further strengthening.The majority of research results are published in academic journals such as Academic Medicine and the International Journal of Sustainability in Higher Education.Presently,the focal point of PBL research in colleges and universities is undergoing a transition from a“single-discipline focus”to an“interdisciplinary integration.”This integration is profoundly intertwined with the nascent fields of modern educational technology and education for sustainable development,thereby offering a novel avenue for the advancement of pedagogical approaches and educational equity.
文摘Background: Scar contractions caused by hand burns seriously impact both the function and appearance of the hand.Consequently,post-burn hand reconstruction is a primary focus of secondary reconstructive surgery performed within the first 10 years after a burn injury.This study aimed to identify developmental trends and research hotspots in post-burn hand reconstruction,providing insights and recommendations for researchers.Methods: Bibliometric and visualization analyses were conducted using Cite Space v6.4.R1(64-bit) and VOS viewer.The Web of Science Core Collection served as the data source.A total of 136 articles between 1997 and2025 were included based on the following keywords: “postburn hand reconstruction” or “postburn hand” or“scar contraction hand deformity.”Results: The field of post-burn hand reconstruction is advancing,as indicated by the overall and annual increase in publications.The United States leads in number of published papers.However,major institutions show low centrality,indicating weak collaboration between countries and regions,with research still dominated by singlecenter studies.The top three most prolific authors were Paul P M van Zuijlen,Fatih Uyghur,and Ersin Uyghur.The keywords “double Z-plasty” and the cluster “flap” not only have high emergence intensity but also appear frequently in recent studies,marking them as current research hotspots.Conclusion: The lack of long-term research and consensus limits further advancements in post-burn hand reconstruction.To address this,multi-center and multi-disciplinary collaborations should be encouraged.Additionally,integrating basic medical research with biomedical engineering could enhance the management and outcomes of post-burn hand reconstruction.
文摘AIM:To gain insight into the future research directions in scleral contact lenses(SCLs)through a comprehensive bibliometrics study.METHODS:The publications related to SCLs were screened from the Web of Science Core Collection(WOSCC)database.All bibliographic information was extracted and used to conduct a performance analysis.CiteSpace and VOSviewer were employed to visualize annual publication counts,journals,authors,countries,institutions,collaboration networks,keywords,and references.RESULTS:A total of 498 articles were included in our analysis and the number of publications about SCLs showed a significant yearly increase.These publications predominantly emanated from 523 institutions across 38 countries,with the United States and Australia leading in frequency.Totally 1361 authors were identified,among whom Vincent J.Stephen exhibited the highest number of publications,while Jacobs S.Deborah received the most citations.Notably,the journal Contact Lens&Anterior Eye emerged as the primary publisher of studies,and it also boasted the highest citation rate.“Fluid-ventilated,gas-permeable scleral contact lens is an effective option for managing severe ocular surface disease and many corneal disorders that would otherwise require penetrating keratoplasty”was the most cited paper published in eye&contact lens in 2005.The most prevalent keywords encompassed“keratoconus”,“scleral contact lenses”,“management”,“contact lenses”,“scleral contact lens”,“ocular surface disease”,“dry eye”,and“contact lens”.CONCLUSION:Although SCLs have demonstrated significant potential in ophthalmological care,the results offer valuable insights pertinent to future research directions and clinical practice.Greater emphasis should be placed on developing enhancements in design,materials,and fitting technique,as well as on reducing the complications associated with SCLs.
基金This study was supported by the Natural Science Foundation of Jilin Province of China,No.20200201495JCJilin Province Health Technology Innovation Project,No.2017J089。
文摘Stem cells have been confirmed to be involved in the occurrence and development of diabetic retinopathy;however,the underlying mechanisms remain unclear.In this study,we used Citespace software to visually analyze 552 articles exploring the stem cell-based treatment of diabetic retinopathy over the past 20 years,which were included in the Web of Science Core Collection.We found the following:(1)a co-citation analysis of the references cited by all 552 articles indicated 15 clusters.In cluster#0,representing the stem cell field,some highly cited landmark studies emerged between 2009–2013.For example,endothelial progenitor cells and diabetic retinopathy gradually received the full attention of scholars,in terms of their relationship and therapeutic prospects.Some researchers also verified the potential of adipose-derived stem cells to differentiate into stable retinal perivascular cells,using a variety of animal models of retinal vascular disease.All of these achievements provided references for the subsequent stem cell research.(2)An analysis of popular keywords among the 552 articles revealed that,during the past 20 years,a relative increase in basic research articles examining stem cells and endothelial progenitor cells for the treatment of diabetic retinopathy was observed.The contents of these articles primarily involved the expression of vascular endothelial growth factor,vascular regeneration,oxidative stress,and inflammatory response.(3)A burst analysis of keywords used in the 552 articles indicated that genetic and cytological research regarding the promotion of angiogenesis was an issue of concern from 2001 to 2012,including several studies addressing the expression of various growth factor genes;from 2014 to 2020,mouse models of diabetic retinopathy were recognized as mature animal models,and the most recent research has focused on macular degeneration,macular edema,neurodegeneration,and inflammatory changes in diabetic animal models.(4)Globally,the current authoritative studies have focused on basic research towards the stem cell treatment of diabetic retinopathy.Existing clinical studies are of low quality and have insufficient evidence levels,and their findings have not yet been widely accepted in clinical practice.Major challenges during stem cell transplantation remain,including stem cell heterogeneity,cell delivery,and the effective homing of stem cells to damaged tissue.However,clinical trials examining potential stem cell-based treatments of diabetic retinopathy,including the use of pluripotent stem cells,retinal pigment epithelial cells,bone marrow mesenchymal stem cells,and endothelial progenitor cells,are currently ongoing,and high-quality clinical evidence is likely to appear in the future,to promote clinical transformation.
文摘Neurogenic bladder is a dysfunction of the lower urinary tract caused by nervous system disor- der. We investigated the trends in publication of articles under the topic ＂neurogenic bladder＂ using bibliometric analysis. Articles on neurogenic bladder, published between 1995 and 2014, were retrieved from the ISI Web of Science citation database. We analyzed the search results for authors, countries, institutions, journals, and top-cited papers. A total of 1,904 articles were re- trieved. There was a small increase in the number of articles on neurogenic bladder from 1995 （n = 43） to 2014 （n = 117）. The USA was the leading country in the total number of articles （n = 598）. However, the number of publications from China has rapidly increased, and China was ranked second in 2014. Emmanuel Chartier-Kastler （n = 65） was the most productive author, and University of Paris VI （Paris 6） （n = 61） was the most productive institution. The Journal of Urology published the greatest number of artides on this topic （n = 285）. Articles on neurogenic bladder were often published in a professional journal under the category Urology ＆ Nephrology, Neurosciences ＆ Neurology, or Rehabilitation. Visualization analysis based on co-citation networks was conducted using CiteSpace III. Visualization analysis revealed that the hot spots in neurogenic bladder were botulinum toxin-A, prazosin, bethanechol, and afferent pathways. These findings provide new insight into the publication trends and hot spots in neurogenic bladder.
基金supported by the Research Project on Medical Education launched by the Medical Education Branch of the Chinese Medical Association and the Medical Education Professional Committee of the Chinese Society of Higher Education in 2018(2018B-N18075)the Education Science Research Project of Beijing University of Chinese Medicine(XJYB2029)the Fundamental Research Funds for the Central Universities(2020-JYB-ZDGG-082).
文摘Objective:The objective of this study is to explore the current situation,clinical research hot spots,and trends of traditional Chinese medicine(TCM)nursing technology in rheumatoid arthritis(RA),to draw a panorama of clinical research,to provide the basis and clues for subsequent high-level evidence integration and further in-depth research.Materials and Methods:Seven databases including China National Knowledge Infrastructure,Chinese Scientific Journal Database(VIP),Wanfang Database,Chinese Biomedical Literature Database(Sino-Med),PubMed,Embase,and the Cochrane Library were searched.The bibliometric method and visualization software CiteSpace were used to conduct a multi-dimensional analysis of the included literature.Results:A total of 805 pieces of literature were included(of them,one was written in German and four in English),and the number of published literature showed an increasing trend year by year.There were only 30(3.73%)pieces of literature published in nursing journals.The hot spots of the co-occurrence map were concentrated in:(1)the nursing of fumigation in RA;(2)the efficacy evaluation of TCM nursing technology on pain,joint malformation,and joint dysfunction caused by RA.The included literature themes focused on five TCM technologies:fumigation,moxibustion,acupoint patching,acupoint injection,and Chinese herbal soaking.The beginning year and strength in TCM fumigation were 2012 and 5.2,and those in moxibustion were 2011 and 3.38.Conclusion:The related studies are on the rise.It has entered the field of international readers with clear research hot spots.However,there are still shortcomings such as little literature published in Chinese nursing core journals,few non-Chinese-related documents,and a lack of international exchanges and cooperation.The current research hot spots in this field are TCM fumigation,and the cutting-edge trend of future research may be fumigation and moxibustion technology.It is suggested that further research can focus on evidence integration and original research on the self-optimization of these two techniques.
基金Supported by National Natural Science Foundation of China(71774049)。
文摘[Objectives]Based on the related literature of benefit finding in China National Knowledge Infrastructure(CNKI),this paper analyzes the research status,hot spots and trends in this field.[Methods]To search for the related literature on benefit finding in China National Knowledge Infrastructure(CNKI),and use Citespace software to visually analyze the number of papers,authors,institutions and keywords.[Results]A total of 204 related papers were obtained,and the annual number of published papers showed a gradual increasing trend.The authors of published papers were represented by Zhang Fenglan,Liu Zhunzhun and Zhang Ting,and the Nursing College of Anhui Medical University published the most papers.The research focus was on social support,coping method and other influencing factors,and qualitative research was the main research type.The key population was breast cancer,stroke patients and their caregivers,and the development trend focused on reliability and validity test and correlation analysis.[Conclusions]The field of benefit finding in China is in the initial exploration stage,and there is little cooperation and exchange between authors and institutions.In the future,academic exchanges and multidisciplinary assistance should be strengthened to promote the rapid development of this field.
